Motif ID: LMO2.p2

Z-value: 1.967


Transcription factors associated with LMO2.p2:

Gene SymbolEntrez IDGene Name
Lmo2 16909 LIM domain only 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Lmo2chr2_+_103809709,
chr2_+_103798150		-0.181.5e-02Click!


Activity profile for motif LMO2.p2.

activity profile for motif LMO2.p2


Sorted Z-values histogram for motif LMO2.p2

Sorted Z-values for motif LMO2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LMO2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_41720091 49.371 NM_001040699
 Mtmr7
myotubularin related protein 7
chr8_+_128519001 43.646 NM_008430
 Kcnk1
potassium channel, subfamily K, member 1
chr8_+_128519295 40.662 Kcnk1
potassium channel, subfamily K, member 1
chrX_+_162676903 39.731 Gpm6b
glycoprotein m6b
chr14_-_55531726 39.465 NM_021551
 Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr15_+_78744862 35.528 Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr4_-_133053867 32.869 Trnp1
TMF1-regulated nuclear protein 1
chr6_+_118016385 32.865 NM_027526
 Rasgef1a
RasGEF domain family, member 1A
chr11_-_69419330 31.989 Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr14_-_30534966 29.891 NM_009785
 Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr7_+_114514258 29.874 NM_021889
 Syt9
synaptotagmin IX
chr2_+_49474840 29.324 Kif5c
kinesin family member 5C
chrX_+_162676870 29.002 NM_001177961
NM_001177962
NM_023122
 Gpm6b


glycoprotein m6b


chr10_-_18463500 28.474 NM_001033258
 D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr12_+_110798661 27.050 Meg3
maternally expressed 3
chr2_+_157387284 26.808 Nnat
neuronatin
chr4_-_133054355 26.205 NM_001081156
 Trnp1
TMF1-regulated nuclear protein 1
chr6_-_23789048 25.390 Cadps2
Ca2+-dependent activator protein for secretion 2
chr7_+_52955153 24.985 NM_009800
 Car11
carbonic anhydrase 11
chr18_+_82753560 24.204 Mbp
myelin basic protein

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 59 entries
Enrichment   P-value GO Accession GO Term
4.63 1.64e-03 GO:0010970 microtubule-based transport
4.63 1.64e-03 GO:0030705 cytoskeleton-dependent intracellular transport
3.31 1.27e-02 GO:0007269 neurotransmitter secretion
3.31 1.27e-02 GO:0050773 regulation of dendrite development
3.18 4.28e-02 GO:0048168 regulation of neuronal synaptic plasticity
2.59 3.54e-02 GO:0001505 regulation of neurotransmitter levels
2.54 9.65e-03 GO:0006836 neurotransmitter transport
2.47 3.37e-06 GO:0010975 regulation of neuron projection development
2.17 1.10e-06 GO:0045664 regulation of neuron differentiation
2.16 2.69e-04 GO:0031344 regulation of cell projection organization
2.05 4.32e-03 GO:0050804 regulation of synaptic transmission
2.04 1.82e-06 GO:0050767 regulation of neurogenesis
1.98 6.96e-03 GO:0051969 regulation of transmission of nerve impulse
1.96 8.40e-04 GO:0007268 synaptic transmission
1.95 2.25e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.94 3.75e-05 GO:0019226 transmission of nerve impulse
1.94 3.75e-05 GO:0035637 multicellular organismal signaling
1.90 3.06e-05 GO:0051960 regulation of nervous system development
1.90 1.58e-02 GO:0031644 regulation of neurological system process
1.87 2.15e-05 GO:0060284 regulation of cell development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 50 entries
Enrichment   P-value GO Accession GO Term
2.98 1.81e-02 GO:0005913 cell-cell adherens junction
2.68 7.71e-05 GO:0008021 synaptic vesicle
2.58 9.32e-03 GO:0043197 dendritic spine
2.51 1.49e-02 GO:0044309 neuron spine
2.49 1.86e-15 GO:0044456 synapse part
2.43 1.76e-02 GO:0030426 growth cone
2.35 7.19e-19 GO:0045202 synapse
2.34 8.05e-05 GO:0030136 clathrin-coated vesicle
2.34 3.29e-02 GO:0030427 site of polarized growth
2.30 5.29e-09 GO:0030424 axon
2.27 1.07e-03 GO:0033267 axon part
2.26 8.03e-04 GO:0019717 synaptosome
2.23 1.74e-04 GO:0045211 postsynaptic membrane
2.22 1.57e-04 GO:0030135 coated vesicle
2.11 2.35e-15 GO:0043005 neuron projection
2.07 1.12e-06 GO:0030425 dendrite
1.99 1.45e-06 GO:0043025 neuronal cell body
1.96 3.68e-08 GO:0044463 cell projection part
1.96 1.07e-02 GO:0034702 ion channel complex
1.95 1.63e-12 GO:0030054 cell junction

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
Enrichment   P-value GO Accession GO Term
2.16 1.95e-02 GO:0005516 calmodulin binding
2.04 3.80e-05 GO:0005083 small GTPase regulator activity
1.89 2.52e-06 GO:0030695 GTPase regulator activity
1.88 2.42e-06 GO:0060589 nucleoside-triphosphatase regulator activity
1.84 1.16e-07 GO:0008092 cytoskeletal protein binding
1.77 4.11e-03 GO:0003779 actin binding
1.60 2.81e-02 GO:0015267 channel activity
1.60 3.07e-02 GO:0022803 passive transmembrane transporter activity
1.46 1.61e-03 GO:0030234 enzyme regulator activity
1.41 1.77e-02 GO:0022857 transmembrane transporter activity
1.41 2.37e-02 GO:0016301 kinase activity
1.40 2.23e-03 GO:0005215 transporter activity
1.39 2.87e-02 GO:0022892 substrate-specific transporter activity
1.27 2.36e-02 GO:0032555 purine ribonucleotide binding
1.27 2.46e-02 GO:0032553 ribonucleotide binding
1.27 2.82e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.26 3.14e-02 GO:0017076 purine nucleotide binding
1.25 1.27e-02 GO:0000166 nucleotide binding
1.21 2.38e-08 GO:0005515 protein binding
1.19 1.96e-02 GO:0046872 metal ion binding