Motif ID: MAFB.p2

Z-value: 3.050


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
Mafb 16658 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafbchr2_-_160192500,
chr2_-_160191800		-0.299.0e-05Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_73509925 88.456 NM_153457
 Rtn1
reticulon 1
chr12_-_73509537 74.162 Rtn1
reticulon 1
chr2_+_90729768 71.200 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr3_+_133903056 66.897 NM_001004367
 Cxxc4
CXXC finger 4
chr6_-_113841295 62.085 Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr14_-_68742863 59.235 Nefm
neurofilament, medium polypeptide
chrX_-_20498021 59.045 NM_001110780
NM_013680
 Syn1

synapsin I

chr2_+_90730089 55.244 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr16_-_67621054 54.545 NM_001145977
NM_178721
 Cadm2

cell adhesion molecule 2

chr4_-_133053867 54.263 Trnp1
TMF1-regulated nuclear protein 1
chr19_+_6427922 53.979 NM_020253
 Nrxn2
neurexin II
chr14_-_68743060 53.562 NM_008691
 Nefm
neurofilament, medium polypeptide
chr11_-_4847968 53.013 NM_010904
 Nefh
neurofilament, heavy polypeptide
chr4_-_133054355 52.210 NM_001081156
 Trnp1
TMF1-regulated nuclear protein 1
chr6_-_113841356 52.165 NM_001036684
 Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr14_-_13655558 48.100 Cadps
Ca2+-dependent secretion activator
chr4_-_151235861 48.004 NM_001081557
NM_001195565
 Camta1

calmodulin binding transcription activator 1

chr7_-_31230463 46.591 Aplp1
amyloid beta (A4) precursor-like protein 1
chr14_-_13655592 46.471 NM_001042617
NM_012061
 Cadps

Ca2+-dependent secretion activator

chr7_-_31230577 46.371 NM_007467
 Aplp1
amyloid beta (A4) precursor-like protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 163 entries
Enrichment   P-value GO Accession GO Term
4.95 2.08e-03 GO:0072384 organelle transport along microtubule
4.22 4.47e-04 GO:0010970 microtubule-based transport
4.22 4.47e-04 GO:0030705 cytoskeleton-dependent intracellular transport
3.81 1.57e-02 GO:0016079 synaptic vesicle exocytosis
3.78 7.73e-03 GO:0007215 glutamate signaling pathway
3.37 1.49e-04 GO:0007269 neurotransmitter secretion
3.37 5.21e-03 GO:0046928 regulation of neurotransmitter secretion
3.20 7.01e-03 GO:0051588 regulation of neurotransmitter transport
3.04 1.76e-02 GO:0021954 central nervous system neuron development
2.91 2.04e-02 GO:0016358 dendrite development
2.52 1.80e-02 GO:0017157 regulation of exocytosis
2.49 6.66e-03 GO:0001505 regulation of neurotransmitter levels
2.42 1.21e-02 GO:0001764 neuron migration
2.35 1.08e-02 GO:0050770 regulation of axonogenesis
2.30 3.22e-09 GO:0007409 axonogenesis
2.30 1.32e-02 GO:0006836 neurotransmitter transport
2.28 1.88e-10 GO:0048812 neuron projection morphogenesis
2.27 9.29e-10 GO:0048667 cell morphogenesis involved in neuron differentiation
2.26 2.83e-05 GO:0006813 potassium ion transport
2.25 2.04e-10 GO:0007268 synaptic transmission

Gene overrepresentation in compartment category:

Showing 1 to 20 of 75 entries
Enrichment   P-value GO Accession GO Term
6.75 3.86e-02 GO:0043083 synaptic cleft
3.85 4.72e-03 GO:0034704 calcium channel complex
3.26 1.11e-02 GO:0030672 synaptic vesicle membrane
3.23 6.11e-05 GO:0043195 terminal button
3.20 5.11e-04 GO:0042734 presynaptic membrane
3.16 8.78e-03 GO:0008287 protein serine/threonine phosphatase complex
3.12 1.91e-05 GO:0030665 clathrin coated vesicle membrane
3.03 1.08e-07 GO:0043679 axon terminus
3.02 9.18e-14 GO:0033267 axon part
3.00 8.36e-08 GO:0030426 growth cone
2.97 6.42e-08 GO:0030427 site of polarized growth
2.89 2.91e-07 GO:0044306 neuron projection terminus
2.84 2.41e-02 GO:0043198 dendritic shaft
2.72 3.21e-21 GO:0030424 axon
2.70 5.18e-05 GO:0044309 neuron spine
2.70 1.38e-04 GO:0030662 coated vesicle membrane
2.68 1.01e-04 GO:0043197 dendritic spine
2.66 1.10e-06 GO:0008021 synaptic vesicle
2.63 5.63e-21 GO:0030425 dendrite
2.57 3.21e-23 GO:0044456 synapse part

Gene overrepresentation in function category:

Showing 1 to 20 of 55 entries
Enrichment   P-value GO Accession GO Term
4.12 8.35e-03 GO:0004683 calmodulin-dependent protein kinase activity
3.16 1.57e-02 GO:0019888 protein phosphatase regulator activity
2.87 2.16e-02 GO:0019208 phosphatase regulator activity
2.62 1.93e-05 GO:0005249 voltage-gated potassium channel activity
2.47 5.36e-07 GO:0022843 voltage-gated cation channel activity
2.45 2.61e-06 GO:0005267 potassium channel activity
2.25 3.36e-07 GO:0005244 voltage-gated ion channel activity
2.25 3.36e-07 GO:0022832 voltage-gated channel activity
2.25 1.99e-04 GO:0005516 calmodulin binding
2.14 7.65e-10 GO:0022836 gated channel activity
1.99 1.82e-06 GO:0005261 cation channel activity
1.97 5.26e-03 GO:0015077 monovalent inorganic cation transmembrane transporter activity
1.88 5.64e-11 GO:0008324 cation transmembrane transporter activity
1.85 1.58e-04 GO:0005083 small GTPase regulator activity
1.83 6.20e-07 GO:0005216 ion channel activity
1.81 1.01e-06 GO:0022838 substrate-specific channel activity
1.79 1.39e-06 GO:0015267 channel activity
1.79 1.33e-02 GO:0022890 inorganic cation transmembrane transporter activity
1.78 1.62e-06 GO:0022803 passive transmembrane transporter activity
1.72 2.91e-10 GO:0015075 ion transmembrane transporter activity