• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: MAFB.p2

Z-value: 3.050

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_73509925	88.456	NM_153457	Rtn1	reticulon 1
chr12_-_73509537	74.162		Rtn1	reticulon 1
chr2_+_90729768	71.200		C1qtnf4	C1q and tumor necrosis factor related protein 4
chr3_+_133903056	66.897	NM_001004367	Cxxc4	CXXC finger 4
chr6_-_113841295	62.085		Atp2b2	ATPase, Ca++ transporting, plasma membrane 2
chr14_-_68742863	59.235		Nefm	neurofilament, medium polypeptide
chrX_-_20498021	59.045	NM_001110780 NM_013680	Syn1	synapsin I
chr2_+_90730089	55.244		C1qtnf4	C1q and tumor necrosis factor related protein 4
chr16_-_67621054	54.545	NM_001145977 NM_178721	Cadm2	cell adhesion molecule 2
chr4_-_133053867	54.263		Trnp1	TMF1-regulated nuclear protein 1
chr19_+_6427922	53.979	NM_020253	Nrxn2	neurexin II
chr14_-_68743060	53.562	NM_008691	Nefm	neurofilament, medium polypeptide
chr11_-_4847968	53.013	NM_010904	Nefh	neurofilament, heavy polypeptide
chr4_-_133054355	52.210	NM_001081156	Trnp1	TMF1-regulated nuclear protein 1
chr6_-_113841356	52.165	NM_001036684	Atp2b2	ATPase, Ca++ transporting, plasma membrane 2
chr14_-_13655558	48.100		Cadps	Ca2+-dependent secretion activator
chr4_-_151235861	48.004	NM_001081557 NM_001195565	Camta1	calmodulin binding transcription activator 1
chr7_-_31230463	46.591		Aplp1	amyloid beta (A4) precursor-like protein 1
chr14_-_13655592	46.471	NM_001042617 NM_012061	Cadps	Ca2+-dependent secretion activator
chr7_-_31230577	46.371	NM_007467	Aplp1	amyloid beta (A4) precursor-like protein 1
chr16_-_20621287	45.505	NM_028420	Camk2n2	calcium/calmodulin-dependent protein kinase II inhibitor 2
chr7_-_31230564	45.432		Aplp1	amyloid beta (A4) precursor-like protein 1
chr5_-_108978950	44.094	NM_007756	Cplx1	complexin 1
chr9_-_86775154	43.820	NM_013669	Snap91	synaptosomal-associated protein 91
chr13_+_118391270	43.437		Hcn1	hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr13_-_78337844	43.309		Nr2f1	nuclear receptor subfamily 2, group F, member 1
chr2_-_80421054	42.904	NM_016965	Nckap1	NCK-associated protein 1
chr2_-_156817751	42.426	NM_013865 NM_180956	Ndrg3	N-myc downstream regulated gene 3
chr13_+_48356795	42.016	NM_031166	Id4	inhibitor of DNA binding 4
chr6_-_58857000	39.811	NM_021432	Nap1l5	nucleosome assembly protein 1-like 5
chr4_-_154719714	38.842		Prkcz	protein kinase C, zeta
chr12_-_73509668	38.827		Rtn1	reticulon 1
chr11_+_104092809	37.548		Mapt	microtubule-associated protein tau
chr1_-_177422630	34.021	NM_001199003 NM_011880	Rgs7	regulator of G protein signaling 7
chr10_-_80945445	33.990	NM_176954	Celf5	CUGBP, Elav-like family member 5
chr12_+_16660245	33.765	NM_008747	Ntsr2	neurotensin receptor 2
chr3_-_55987612	33.315	NM_030595	Nbea	neurobeachin
chr6_-_113991945	32.310	NM_009723	Atp2b2	ATPase, Ca++ transporting, plasma membrane 2
chr12_+_16660521	31.892		Ntsr2	neurotensin receptor 2
chr3_+_13471681	31.551		Ralyl	RALY RNA binding protein-like
chr12_+_50484907	31.159		Foxg1	forkhead box G1
chr6_+_115084919	31.038	NM_001111015 NM_013681	Syn2	synapsin II
chr11_+_54117703	30.478	NM_001033597 NM_144823	Acsl6	acyl-CoA synthetase long-chain family member 6
chr18_+_37303622	29.889	NM_001003672	Pcdhac2	protocadherin alpha subfamily C, 2
chr6_+_115085096	28.898		Syn2	synapsin II
chr18_-_43059156	28.596		Ppp2r2b	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr18_+_45719732	28.310	NM_080465	Kcnn2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr4_-_154719834	28.282	NM_001039079	Prkcz	protein kinase C, zeta
chr14_-_24823370	27.904	NM_010610	Kcnma1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr4_+_129662110	27.754		Bai2	brain-specific angiogenesis inhibitor 2
chr14_-_55531726	27.564	NM_021551	Slc22a17	solute carrier family 22 (organic cation transporter), member 17
chr2_+_119625249	27.303	NM_019392	Tyro3	TYRO3 protein tyrosine kinase 3
chr10_+_106708886	27.182	NM_001033223 NM_001039354	Lin7a	lin-7 homolog A (C. elegans)
chr10_+_59569052	26.874		Spock2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr8_-_67171692	26.274		Cpe	carboxypeptidase E
chr18_-_25912171	26.259		Celf4	CUGBP, Elav-like family member 4
chr8_+_128519295	26.092		Kcnk1	potassium channel, subfamily K, member 1
chrX_+_7496899	26.026	NM_013892	Pcsk1n	proprotein convertase subtilisin/kexin type 1 inhibitor
chr8_-_67171481	25.870		Cpe	carboxypeptidase E
chr8_-_67171805	25.853	NM_013494	Cpe	carboxypeptidase E
chr4_+_129662284	25.853	NM_173071	Bai2	brain-specific angiogenesis inhibitor 2
chr17_-_24826873	25.791	NM_011522	Syngr3	synaptogyrin 3
chr15_+_87455659	25.774	NM_134096	Fam19a5	family with sequence similarity 19, member A5
chr2_-_167014273	25.655	NM_008420	Kcnb1	potassium voltage gated channel, Shab-related subfamily, member 1
chr5_+_110973321	25.299	NM_198306	Galnt9	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr18_+_45719464	25.274		Kcnn2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr6_-_77929660	25.240	NM_001109764 NM_009819 NM_145732	Ctnna2	catenin (cadherin associated protein), alpha 2
chr7_+_28438881	25.212	NM_028417	Ttc9b	tetratricopeptide repeat domain 9B
chr18_-_43219062	24.926	NM_028392	Ppp2r2b	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chrX_+_7215705	24.846	NM_009305	Syp	synaptophysin
chr3_-_57651409	24.582		Pfn2	profilin 2
chr13_+_118391126	24.465	NM_010408	Hcn1	hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr1_-_177422520	24.272		Rgs7	regulator of G protein signaling 7
chr8_-_87461251	24.105	NM_019945	Mast1	microtubule associated serine/threonine kinase 1
chr9_-_91259829	24.095		Zic1	zinc finger protein of the cerebellum 1
chr7_+_106415956	23.776	NM_001048167 NM_010837	Mtap6	microtubule-associated protein 6
chr10_+_69903653	23.730	NM_001143776 NM_024244	Fam13c	family with sequence similarity 13, member C
chr13_-_69138164	23.717		Adcy2	adenylate cyclase 2
chr16_-_45724422	23.626	NM_019754	Tagln3	transgelin 3
chr19_+_4745119	23.396		Spnb3	spectrin beta 3
chr13_+_54472806	23.389		Cplx2	complexin 2
chr13_+_104899869	23.338	NM_144838	Sgtb	small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr13_+_104899814	23.215		Sgtb	small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr6_-_92431385	23.134	NM_001134460	Prickle2	prickle homolog 2 (Drosophila)
chr9_-_108499855	23.107	NM_028944	P4htm	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr15_-_90880241	22.837	NM_001109040 NM_001109041 NM_001109042 NM_016705	Kif21a	kinesin family member 21A
chr1_+_160292665	22.747		Astn1	astrotactin 1
chr5_-_52957466	22.705		Lgi2	leucine-rich repeat LGI family, member 2
chr19_-_4989865	22.700	NM_153553	Npas4	neuronal PAS domain protein 4
chr2_+_136539143	22.600	NM_011428	Snap25	synaptosomal-associated protein 25
chr15_-_44584003	22.419	NM_178765	Sybu	syntabulin (syntaxin-interacting)
chr9_+_74918979	22.029	NM_010864	Myo5a	myosin VA
chr12_+_45429966	21.949		Nrcam	neuron-glia-CAM-related cell adhesion molecule
chr13_-_25361773	21.701	NM_009513	Nrsn1	neurensin 1
chr13_-_69138229	21.657		Adcy2	adenylate cyclase 2
chr13_-_69138418	21.636	NM_153534	Adcy2	adenylate cyclase 2
chr5_+_34339351	21.594		Nat8l	N-acetyltransferase 8-like
chr4_+_102432879	21.576		Sgip1	SH3-domain GRB2-like (endophilin) interacting protein 1
chr16_-_45724720	21.504		Tagln3	transgelin 3
chrX_+_91881454	21.478		Gspt2	G1 to S phase transition 2
chr5_+_37633353	21.172		Crmp1	collapsin response mediator protein 1
chr10_-_80945379	21.170		Celf5	CUGBP, Elav-like family member 5
chr17_-_24826812	21.154		Syngr3	synaptogyrin 3
chr10_+_59569206	21.119		Spock2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr6_-_28781687	21.026	NM_138682	Lrrc4	leucine rich repeat containing 4
chr14_-_30534966	20.788	NM_009785	Cacna2d3	calcium channel, voltage-dependent, alpha2/delta subunit 3
chr2_+_136539202	20.630		Snap25	synaptosomal-associated protein 25
chr18_+_35020867	20.598		Egr1	early growth response 1
chr9_+_110147867	20.404		Cspg5	chondroitin sulfate proteoglycan 5
chr1_+_160292470	20.232	NM_007495	Astn1	astrotactin 1
chr4_-_126430511	20.187	NM_011986	Ncdn	neurochondrin
chr18_-_16967100	20.170		Cdh2	cadherin 2
chr2_+_119625463	20.108		Tyro3	TYRO3 protein tyrosine kinase 3
chr2_-_151458299	20.087		Snph	syntaphilin
chr15_+_103333554	20.070	NM_008800	Pde1b	phosphodiesterase 1B, Ca2+-calmodulin dependent
chr8_+_125935470	20.050		Tubb3	tubulin, beta 3
chr13_+_54472705	19.926	NM_009946	Cplx2	complexin 2
chr4_+_102432943	19.909	NM_144906	Sgip1	SH3-domain GRB2-like (endophilin) interacting protein 1
chr2_-_79294977	19.806		Neurod1	neurogenic differentiation 1
chr9_-_86775282	19.673		Snap91	synaptosomal-associated protein 91
chr5_+_37633317	19.511	NM_001136058	Crmp1	collapsin response mediator protein 1
chr2_-_25174498	19.274		Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr8_-_87461220	19.157		Mast1	microtubule associated serine/threonine kinase 1
chr15_-_77137015	19.056		Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_+_119625505	19.017		Tyro3	TYRO3 protein tyrosine kinase 3
chr1_+_66221851	18.962	NM_001039934 NM_008632	Mtap2	microtubule-associated protein 2
chr2_-_102241003	18.946		Trim44	tripartite motif-containing 44
chr4_-_109960078	18.922	NM_001038698	Elavl4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr15_-_37389073	18.776	NM_001170867 NM_001170868	Ncald	neurocalcin delta
chr9_-_69989285	18.638	NM_029784	Fam81a	family with sequence similarity 81, member A
chr9_-_62384483	18.603		Coro2b	coronin, actin binding protein, 2B
chr15_+_74394184	18.546		Bai1	brain-specific angiogenesis inhibitor 1
chr3_-_117063090	18.523		D3Bwg0562e	DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr13_+_58909236	18.444		Ntrk2	neurotrophic tyrosine kinase, receptor, type 2
chr14_-_55734213	18.341	NM_001003829	Jph4	junctophilin 4
chr5_-_21850490	18.299	NM_011261	Reln	reelin
chr11_-_6375845	17.945	NM_011221	Purb	purine rich element binding protein B
chr11_-_118770859	17.841		Rbfox3	RNA binding protein, fox-1 homolog (C. elegans) 3
chr15_-_77136972	17.720		Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr13_+_48356487	17.715		Id4	inhibitor of DNA binding 4
chr9_+_14080805	17.656		Sesn3	sestrin 3
chr15_+_30102306	17.625	NM_008729	Ctnnd2	catenin (cadherin associated protein), delta 2
chr9_-_69989168	17.598		Fam81a	family with sequence similarity 81, member A
chr6_-_77929543	17.519		Ctnna2	catenin (cadherin associated protein), alpha 2
chr4_+_103292164	17.360		Dab1	disabled homolog 1 (Drosophila)
chr11_+_54117299	17.343	NM_001033598	Acsl6	acyl-CoA synthetase long-chain family member 6
chr6_+_5675638	17.300	NM_001191023 NM_001191025 NM_001191026 NM_001191027 NM_010063	Dync1i1	dynein cytoplasmic 1 intermediate chain 1
chr10_+_34017221	17.274	NM_030203	Tspyl4	TSPY-like 4
chr18_+_45719101	17.225		Kcnn2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr15_+_54402914	17.214	NM_178920	Mal2	mal, T-cell differentiation protein 2
chr4_+_101180625	17.144		Dnajc6	DnaJ (Hsp40) homolog, subfamily C, member 6
chr1_-_33964439	17.121	NM_177235	Bend6	BEN domain containing 6
chr14_+_64225366	17.049	NM_173393	Xkr6	X Kell blood group precursor related family member 6 homolog
chr12_-_113749361	16.981		Tmem179	transmembrane protein 179
chr9_+_106356125	16.934	NM_021567	Pcbp4	poly(rC) binding protein 4
chr11_-_116274124	16.651		Rnf157	ring finger protein 157
chr7_+_64846558	16.631		Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr2_+_48805027	16.511	NM_029924	Mbd5	methyl-CpG binding domain protein 5
chr1_+_87791084	16.508	NM_022417	Itm2c	integral membrane protein 2C
chr5_-_8622882	16.492	NM_198620	Rundc3b	RUN domain containing 3B
chr4_-_4065585	16.416	NM_001002927	Penk	preproenkephalin
chr12_+_45429857	16.415	NM_001146031 NM_176930	Nrcam	neuron-glia-CAM-related cell adhesion molecule
chr6_-_8728481	16.406	NM_010492	Ica1	islet cell autoantigen 1
chr18_-_25912453	16.404	NM_001146292 NM_001146293 NM_001146294 NM_001146295 NM_001174074 NM_133195	Celf4	CUGBP, Elav-like family member 4
chr6_-_77929575	16.389		Ctnna2	catenin (cadherin associated protein), alpha 2
chr11_+_104092749	16.341	NM_001038609 NM_010838	Mapt	microtubule-associated protein tau
chr12_+_53604952	16.237		Arhgap5	Rho GTPase activating protein 5
chr12_-_113749313	16.182		Tmem179	transmembrane protein 179
chr3_+_69120782	16.046	NM_178726	Ppm1l	protein phosphatase 1 (formerly 2C)-like
chr2_-_151458256	16.030	NM_198214	Snph	syntaphilin
chr14_+_68701838	15.888	NM_010910	Nefl	neurofilament, light polypeptide
chr6_+_107479719	15.883	NM_008516	Lrrn1	leucine rich repeat protein 1, neuronal
chr7_+_129432810	15.777		Prkcb	protein kinase C, beta
chr3_+_64913564	15.648	NM_010597	Kcnab1	potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr9_+_14080744	15.622	NM_030261	Sesn3	sestrin 3
chr7_-_25774918	15.558		Atp1a3	ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr9_-_97933599	15.528		Clstn2	calsyntenin 2
chr14_+_76362274	15.460		Kctd4	potassium channel tetramerisation domain containing 4
chr6_-_77929685	15.319		Ctnna2	catenin (cadherin associated protein), alpha 2
chr3_-_57651621	15.238	NM_019410	Pfn2	profilin 2
chr15_+_54402988	15.236		Mal2	mal, T-cell differentiation protein 2
chr1_+_60466499	15.011		Abi2	abl-interactor 2
chr15_-_77950450	15.009		Cacng2	calcium channel, voltage-dependent, gamma subunit 2
chr18_+_36446680	14.969		Pura	purine rich element binding protein A
chr1_+_60466568	14.880		Abi2	abl-interactor 2
chrX_+_5624820	14.771		Nudt11	nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr16_+_20695034	14.623	NM_133778	Fam131a	family with sequence similarity 131, member A
chr12_-_113749363	14.619	NM_178915	Tmem179	transmembrane protein 179
chr1_+_60466462	14.607	NM_001198570 NM_001198571 NM_198127	Abi2	abl-interactor 2
chr1_+_169528492	14.576	NM_009107	Rxrg	retinoid X receptor gamma
chr2_+_124962427	14.574	NM_001162934	Ctxn2	cortexin 2
chr3_-_84063605	14.472		Trim2	tripartite motif-containing 2
chr9_+_43875175	14.464		Usp2	ubiquitin specific peptidase 2
chr5_+_88994386	14.386		Rufy3	RUN and FYVE domain containing 3
chr3_-_87804277	14.173	NM_001109758 NM_007529	Bcan	brevican
chr11_-_75609557	14.158	NM_007873	Doc2b	double C2, beta
chr2_+_58998938	14.024		Pkp4	plakophilin 4
chr12_+_112127468	13.998	NM_001081057	Tecpr2	tectonin beta-propeller repeat containing 2
chr2_+_156301651	13.840		Epb4.1l1	erythrocyte protein band 4.1-like 1
chr1_+_74331503	13.828	NM_001039509 NM_025580	Pnkd	paroxysmal nonkinesiogenic dyskinesia

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.89	3.78e-28	GO:0007399	nervous system development
1.46	4.93e-24	GO:0051179	localization
1.99	1.50e-21	GO:0048699	generation of neurons
1.95	2.03e-21	GO:0022008	neurogenesis
1.48	2.77e-21	GO:0051234	establishment of localization
1.48	1.20e-20	GO:0006810	transport
2.05	3.32e-16	GO:0030182	neuron differentiation
2.14	1.63e-14	GO:0048666	neuron development
1.42	3.69e-14	GO:0048731	system development
1.39	1.84e-13	GO:0048856	anatomical structure development
2.20	2.63e-12	GO:0031175	neuron projection development
2.13	3.73e-11	GO:0019226	transmission of nerve impulse
2.13	3.73e-11	GO:0035637	multicellular organismal signaling
1.83	4.11e-11	GO:0006812	cation transport
1.51	5.88e-11	GO:0023051	regulation of signaling
1.70	7.55e-11	GO:0006811	ion transport
1.20	1.00e-10	GO:0044237	cellular metabolic process
1.34	1.38e-10	GO:0048518	positive regulation of biological process
2.28	1.88e-10	GO:0048812	neuron projection morphogenesis
1.33	1.97e-10	GO:0007275	multicellular organismal development
2.25	2.04e-10	GO:0007268	synaptic transmission
1.31	2.09e-10	GO:0032502	developmental process
1.36	4.08e-10	GO:0048522	positive regulation of cellular process
1.65	6.28e-10	GO:0048468	cell development
1.26	8.99e-10	GO:0019222	regulation of metabolic process
2.27	9.29e-10	GO:0048667	cell morphogenesis involved in neuron differentiation
1.74	1.03e-09	GO:0007154	cell communication
1.85	1.31e-09	GO:0030001	metal ion transport
1.67	3.04e-09	GO:0051049	regulation of transport
2.30	3.22e-09	GO:0007409	axonogenesis
1.39	3.24e-09	GO:0030154	cell differentiation
1.85	3.87e-09	GO:0030030	cell projection organization
1.27	5.14e-09	GO:0031323	regulation of cellular metabolic process
1.38	1.06e-08	GO:0048869	cellular developmental process
2.11	1.71e-08	GO:0045664	regulation of neuron differentiation
2.04	2.14e-08	GO:0048858	cell projection morphogenesis
1.55	2.73e-08	GO:0006793	phosphorus metabolic process
1.54	3.61e-08	GO:0032879	regulation of localization
1.98	4.21e-08	GO:0050767	regulation of neurogenesis
1.30	5.02e-08	GO:0016043	cellular component organization
1.34	5.23e-08	GO:0044267	cellular protein metabolic process
1.54	6.94e-08	GO:0006796	phosphate metabolic process
2.00	7.13e-08	GO:0032990	cell part morphogenesis
1.58	8.56e-08	GO:0051649	establishment of localization in cell
1.91	1.01e-07	GO:0051960	regulation of nervous system development
1.40	1.37e-07	GO:0006464	protein modification process
1.99	1.66e-07	GO:0000904	cell morphogenesis involved in differentiation
2.16	1.95e-07	GO:0031644	regulation of neurological system process
1.52	2.36e-07	GO:0051641	cellular localization
1.83	4.48e-07	GO:0007267	cell-cell signaling
2.18	5.18e-07	GO:0051969	regulation of transmission of nerve impulse
1.37	6.44e-07	GO:0043412	macromolecule modification
1.82	9.62e-07	GO:0060284	regulation of cell development
1.15	1.12e-06	GO:0008152	metabolic process
1.09	1.20e-06	GO:0009987	cellular process
1.55	1.40e-06	GO:0051128	regulation of cellular component organization
1.24	1.70e-06	GO:0080090	regulation of primary metabolic process
1.64	2.43e-06	GO:0016192	vesicle-mediated transport
2.18	2.77e-06	GO:0050804	regulation of synaptic transmission
1.26	3.44e-06	GO:0071840	cellular component organization or biogenesis
1.47	4.28e-06	GO:0010646	regulation of cell communication
1.75	4.46e-06	GO:0000902	cell morphogenesis
2.22	7.95e-06	GO:0010975	regulation of neuron projection development
1.31	1.04e-05	GO:0071842	cellular component organization at cellular level
1.88	1.27e-05	GO:0015672	monovalent inorganic cation transport
1.19	1.30e-05	GO:0044260	cellular macromolecule metabolic process
1.37	1.51e-05	GO:0065009	regulation of molecular function
1.72	1.90e-05	GO:0060341	regulation of cellular localization
1.71	2.15e-05	GO:0007417	central nervous system development
2.26	2.83e-05	GO:0006813	potassium ion transport
1.15	3.14e-05	GO:0044238	primary metabolic process
1.76	3.18e-05	GO:0007610	behavior
1.74	3.60e-05	GO:0072521	purine-containing compound metabolic process
1.59	4.95e-05	GO:0046907	intracellular transport
1.36	4.97e-05	GO:0051239	regulation of multicellular organismal process
1.73	5.50e-05	GO:0044057	regulation of system process
1.50	5.82e-05	GO:0016310	phosphorylation
2.04	7.52e-05	GO:0031344	regulation of cell projection organization
1.43	9.95e-05	GO:0035556	intracellular signal transduction
3.37	1.49e-04	GO:0007269	neurotransmitter secretion
1.64	1.63e-04	GO:0032989	cellular component morphogenesis
1.78	1.67e-04	GO:0051046	regulation of secretion
1.28	2.03e-04	GO:0048523	negative regulation of cellular process
1.76	2.24e-04	GO:0007420	brain development
1.26	2.28e-04	GO:0048519	negative regulation of biological process
1.21	2.66e-04	GO:0060255	regulation of macromolecule metabolic process
1.38	2.77e-04	GO:0009966	regulation of signal transduction
1.24	3.20e-04	GO:0019538	protein metabolic process
2.10	3.38e-04	GO:0060627	regulation of vesicle-mediated transport
1.38	3.67e-04	GO:0050790	regulation of catalytic activity
1.52	3.79e-04	GO:0019220	regulation of phosphate metabolic process
1.52	3.79e-04	GO:0051174	regulation of phosphorus metabolic process
1.94	4.03e-04	GO:0030900	forebrain development
1.72	4.44e-04	GO:0006163	purine nucleotide metabolic process
4.22	4.47e-04	GO:0010970	microtubule-based transport
4.22	4.47e-04	GO:0030705	cytoskeleton-dependent intracellular transport
1.26	4.50e-04	GO:0071841	cellular component organization or biogenesis at cellular level
1.55	5.03e-04	GO:0040011	locomotion
1.47	5.46e-04	GO:0045595	regulation of cell differentiation
1.35	5.68e-04	GO:0009653	anatomical structure morphogenesis
1.50	5.99e-04	GO:0006468	protein phosphorylation
1.30	7.06e-04	GO:0065008	regulation of biological quality
1.22	1.94e-03	GO:0051171	regulation of nitrogen compound metabolic process
4.95	2.08e-03	GO:0072384	organelle transport along microtubule
1.42	2.34e-03	GO:2000026	regulation of multicellular organismal development
1.53	2.37e-03	GO:0009605	response to external stimulus
1.61	2.72e-03	GO:0061024	membrane organization
1.76	2.88e-03	GO:0009144	purine nucleoside triphosphate metabolic process
1.22	3.09e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22	3.15e-03	GO:0009889	regulation of biosynthetic process
1.60	3.32e-03	GO:0006873	cellular ion homeostasis
1.59	3.46e-03	GO:0055082	cellular chemical homeostasis
1.73	3.76e-03	GO:0009150	purine ribonucleotide metabolic process
1.14	3.82e-03	GO:0043170	macromolecule metabolic process
1.60	4.00e-03	GO:0016044	cellular membrane organization
1.73	4.42e-03	GO:0009141	nucleoside triphosphate metabolic process
1.37	4.46e-03	GO:0050793	regulation of developmental process
1.53	4.82e-03	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
2.07	4.83e-03	GO:0007626	locomotory behavior
2.23	5.19e-03	GO:0003001	generation of a signal involved in cell-cell signaling
2.23	5.19e-03	GO:0023061	signal release
3.37	5.21e-03	GO:0046928	regulation of neurotransmitter secretion
1.75	5.22e-03	GO:0009205	purine ribonucleoside triphosphate metabolic process
1.44	5.53e-03	GO:0031399	regulation of protein modification process
2.49	6.66e-03	GO:0001505	regulation of neurotransmitter levels
1.74	6.96e-03	GO:0009199	ribonucleoside triphosphate metabolic process
3.20	7.01e-03	GO:0051588	regulation of neurotransmitter transport
1.63	7.25e-03	GO:0051050	positive regulation of transport
1.94	7.27e-03	GO:0042391	regulation of membrane potential
1.28	7.43e-03	GO:0048583	regulation of response to stimulus
2.12	7.70e-03	GO:0007411	axon guidance
3.78	7.73e-03	GO:0007215	glutamate signaling pathway
2.19	8.42e-03	GO:0051640	organelle localization
1.44	8.46e-03	GO:0055085	transmembrane transport
1.10	8.66e-03	GO:0050794	regulation of cellular process
1.21	8.69e-03	GO:0031326	regulation of cellular biosynthetic process
2.35	1.08e-02	GO:0050770	regulation of axonogenesis
1.09	1.15e-02	GO:0065007	biological regulation
1.51	1.18e-02	GO:0019725	cellular homeostasis
2.42	1.21e-02	GO:0001764	neuron migration
1.54	1.25e-02	GO:0050801	ion homeostasis
1.68	1.28e-02	GO:0009259	ribonucleotide metabolic process
2.30	1.32e-02	GO:0006836	neurotransmitter transport
1.46	1.36e-02	GO:0042325	regulation of phosphorylation
1.74	1.48e-02	GO:0072523	purine-containing compound catabolic process
1.21	1.50e-02	GO:0010468	regulation of gene expression
3.81	1.57e-02	GO:0016079	synaptic vesicle exocytosis
3.04	1.76e-02	GO:0021954	central nervous system neuron development
2.52	1.80e-02	GO:0017157	regulation of exocytosis
1.36	1.98e-02	GO:0032268	regulation of cellular protein metabolic process
2.91	2.04e-02	GO:0016358	dendrite development
1.73	2.67e-02	GO:0006195	purine nucleotide catabolic process
1.76	3.19e-02	GO:0009207	purine ribonucleoside triphosphate catabolic process
1.58	3.40e-02	GO:0016477	cell migration
1.76	3.70e-02	GO:0009203	ribonucleoside triphosphate catabolic process
1.50	3.94e-02	GO:0006753	nucleoside phosphate metabolic process
1.50	3.94e-02	GO:0009117	nucleotide metabolic process
2.06	4.02e-02	GO:0006887	exocytosis
2.16	4.11e-02	GO:0021953	central nervous system neuron differentiation
1.09	4.46e-02	GO:0050789	regulation of biological process
1.33	4.58e-02	GO:0044248	cellular catabolic process
1.71	4.73e-02	GO:0051056	regulation of small GTPase mediated signal transduction
1.74	4.95e-02	GO:0009146	purine nucleoside triphosphate catabolic process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.28	6.51e-36	GO:0005737	cytoplasm
2.48	1.20e-35	GO:0043005	neuron projection
1.20	6.85e-34	GO:0005622	intracellular
1.21	8.12e-33	GO:0044424	intracellular part
2.52	8.21e-32	GO:0045202	synapse
1.83	1.33e-23	GO:0042995	cell projection
2.57	3.21e-23	GO:0044456	synapse part
2.72	3.21e-21	GO:0030424	axon
2.63	5.63e-21	GO:0030425	dendrite
1.10	6.04e-20	GO:0005623	cell
1.10	6.04e-20	GO:0044464	cell part
2.41	2.70e-19	GO:0044297	cell body
2.45	3.20e-19	GO:0043025	neuronal cell body
1.40	9.19e-16	GO:0043234	protein complex
1.25	2.43e-15	GO:0044444	cytoplasmic part
2.12	3.38e-15	GO:0044463	cell projection part
1.32	5.61e-15	GO:0071944	cell periphery
1.32	8.78e-15	GO:0005886	plasma membrane
1.16	1.85e-14	GO:0043226	organelle
1.16	2.80e-14	GO:0043229	intracellular organelle
3.02	9.18e-14	GO:0033267	axon part
1.32	1.39e-12	GO:0032991	macromolecular complex
1.42	1.01e-10	GO:0044459	plasma membrane part
1.15	1.33e-10	GO:0043227	membrane-bounded organelle
1.15	2.81e-10	GO:0043231	intracellular membrane-bounded organelle
1.73	7.65e-10	GO:0030054	cell junction
2.51	9.47e-10	GO:0045211	postsynaptic membrane
1.57	4.29e-09	GO:0005626	insoluble fraction
1.57	1.09e-08	GO:0005624	membrane fraction
1.48	1.32e-08	GO:0000267	cell fraction
1.42	3.59e-08	GO:0005829	cytosol
2.97	6.42e-08	GO:0030427	site of polarized growth
3.00	8.36e-08	GO:0030426	growth cone
3.03	1.08e-07	GO:0043679	axon terminus
2.40	1.91e-07	GO:0030136	clathrin-coated vesicle
2.89	2.91e-07	GO:0044306	neuron projection terminus
1.57	3.06e-07	GO:0031982	vesicle
1.92	4.01e-07	GO:0048471	perinuclear region of cytoplasm
1.44	4.26e-07	GO:0031090	organelle membrane
2.28	4.33e-07	GO:0030135	coated vesicle
1.57	8.94e-07	GO:0031410	cytoplasmic vesicle
2.66	1.10e-06	GO:0008021	synaptic vesicle
2.18	2.42e-06	GO:0012506	vesicle membrane
1.63	3.79e-06	GO:0031988	membrane-bounded vesicle
2.19	1.02e-05	GO:0030659	cytoplasmic vesicle membrane
1.63	1.10e-05	GO:0016023	cytoplasmic membrane-bounded vesicle
2.17	1.17e-05	GO:0044433	cytoplasmic vesicle part
2.28	1.24e-05	GO:0019717	synaptosome
1.19	1.61e-05	GO:0044422	organelle part
3.12	1.91e-05	GO:0030665	clathrin coated vesicle membrane
1.19	2.73e-05	GO:0044446	intracellular organelle part
2.08	2.84e-05	GO:0034702	ion channel complex
2.70	5.18e-05	GO:0044309	neuron spine
3.23	6.11e-05	GO:0043195	terminal button
2.68	1.01e-04	GO:0043197	dendritic spine
2.70	1.38e-04	GO:0030662	coated vesicle membrane
2.34	2.12e-04	GO:0034703	cation channel complex
1.11	2.97e-04	GO:0016020	membrane
1.43	4.79e-04	GO:0012505	endomembrane system
3.20	5.11e-04	GO:0042734	presynaptic membrane
1.38	6.45e-04	GO:0005794	Golgi apparatus
2.44	6.83e-04	GO:0014069	postsynaptic density
1.15	7.52e-04	GO:0005634	nucleus
1.68	2.25e-03	GO:0044431	Golgi apparatus part
3.85	4.72e-03	GO:0034704	calcium channel complex
3.16	8.78e-03	GO:0008287	protein serine/threonine phosphatase complex
2.42	9.16e-03	GO:0008076	voltage-gated potassium channel complex
2.42	9.16e-03	GO:0034705	potassium channel complex
3.26	1.11e-02	GO:0030672	synaptic vesicle membrane
1.82	1.14e-02	GO:0031252	cell leading edge
1.85	1.75e-02	GO:0000139	Golgi membrane
2.39	2.40e-02	GO:0030133	transport vesicle
2.84	2.41e-02	GO:0043198	dendritic shaft
6.75	3.86e-02	GO:0043083	synaptic cleft
1.99	4.70e-02	GO:0019898	extrinsic to membrane

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.39	2.81e-38	GO:0005515	protein binding
1.20	2.80e-31	GO:0005488	binding
1.88	5.64e-11	GO:0008324	cation transmembrane transporter activity
1.72	2.91e-10	GO:0015075	ion transmembrane transporter activity
2.14	7.65e-10	GO:0022836	gated channel activity
1.63	4.11e-09	GO:0022891	substrate-specific transmembrane transporter activity
1.60	4.54e-09	GO:0019899	enzyme binding
1.58	6.33e-09	GO:0022892	substrate-specific transporter activity
1.34	2.63e-08	GO:0000166	nucleotide binding
1.57	2.70e-08	GO:0022857	transmembrane transporter activity
1.37	9.97e-08	GO:0032555	purine ribonucleotide binding
1.37	1.07e-07	GO:0032553	ribonucleotide binding
1.36	1.66e-07	GO:0017076	purine nucleotide binding
2.25	3.36e-07	GO:0005244	voltage-gated ion channel activity
2.25	3.36e-07	GO:0022832	voltage-gated channel activity
2.47	5.36e-07	GO:0022843	voltage-gated cation channel activity
1.36	5.81e-07	GO:0035639	purine ribonucleoside triphosphate binding
1.83	6.20e-07	GO:0005216	ion channel activity
1.81	1.01e-06	GO:0022838	substrate-specific channel activity
1.46	1.02e-06	GO:0005215	transporter activity
1.79	1.39e-06	GO:0015267	channel activity
1.78	1.62e-06	GO:0022803	passive transmembrane transporter activity
1.99	1.82e-06	GO:0005261	cation channel activity
1.58	1.90e-06	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.38	2.00e-06	GO:0032559	adenyl ribonucleotide binding
2.45	2.61e-06	GO:0005267	potassium channel activity
1.37	3.36e-06	GO:0030554	adenyl nucleotide binding
1.61	9.91e-06	GO:0004672	protein kinase activity
1.36	1.46e-05	GO:0005524	ATP binding
1.50	1.54e-05	GO:0016301	kinase activity
2.62	1.93e-05	GO:0005249	voltage-gated potassium channel activity
1.22	2.68e-05	GO:0046872	metal ion binding
1.69	3.74e-05	GO:0004674	protein serine/threonine kinase activity
1.21	4.78e-05	GO:0043167	ion binding
1.21	4.88e-05	GO:0043169	cation binding
1.43	7.30e-05	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.85	1.58e-04	GO:0005083	small GTPase regulator activity
1.45	1.63e-04	GO:0030234	enzyme regulator activity
2.25	1.99e-04	GO:0005516	calmodulin binding
1.65	2.15e-04	GO:0060589	nucleoside-triphosphatase regulator activity
1.65	3.39e-04	GO:0030695	GTPase regulator activity
1.15	6.99e-04	GO:0003824	catalytic activity
1.52	1.43e-03	GO:0019904	protein domain specific binding
1.64	1.51e-03	GO:0032403	protein complex binding
1.97	5.26e-03	GO:0015077	monovalent inorganic cation transmembrane transporter activity
1.49	6.15e-03	GO:0008092	cytoskeletal protein binding
4.12	8.35e-03	GO:0004683	calmodulin-dependent protein kinase activity
1.64	8.46e-03	GO:0019900	kinase binding
1.28	1.12e-02	GO:0008270	zinc ion binding
1.79	1.33e-02	GO:0022890	inorganic cation transmembrane transporter activity
3.16	1.57e-02	GO:0019888	protein phosphatase regulator activity
2.87	2.16e-02	GO:0019208	phosphatase regulator activity
1.58	3.00e-02	GO:0042578	phosphoric ester hydrolase activity
1.65	4.09e-02	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.50	4.62e-02	GO:0016874	ligase activity