Motif ID: MAZ.p2

Z-value: 1.740


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
Maz 17188 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mazchr7_-_134169581-0.263.1e-04Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_156224757 28.090 NM_001039094
NM_177274
 Negr1

neuronal growth regulator 1

chrX_+_53985133 25.499 NM_001077361
 Fhl1
four and a half LIM domains 1
chr13_-_78337844 23.555 Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr14_-_46149660 23.329 NM_146054
 Fermt2
fermitin family homolog 2 (Drosophila)
chr1_-_82287990 23.171 NM_010570
 Irs1
insulin receptor substrate 1
chrX_+_53984926 22.920 NM_010211
 Fhl1
four and a half LIM domains 1
chr4_-_82151590 21.417 Nfib
nuclear factor I/B
chr15_+_98465328 20.054 Cacnb3
calcium channel, voltage-dependent, beta 3 subunit
chr4_+_138011061 19.593 NM_025451
 Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr19_-_44482138 19.589 NM_009127
 Scd1
stearoyl-Coenzyme A desaturase 1
chr9_+_98325217 19.213 Rbp1
retinol binding protein 1, cellular
chr19_-_44482033 18.936 Scd1
stearoyl-Coenzyme A desaturase 1
chr9_+_43893029 18.850 Usp2
ubiquitin specific peptidase 2
chrX_+_70728939 18.178 NM_007542
 Bgn
biglycan
chr4_+_137283714 18.176 Rap1gap
Rap1 GTPase-activating protein
chr9_+_106356125 17.883 NM_021567
 Pcbp4
poly(rC) binding protein 4
chr9_+_43892984 17.735 NM_198091
 Usp2
ubiquitin specific peptidase 2
chr19_+_27292039 17.529 Vldlr
very low density lipoprotein receptor
chr6_+_4455686 17.296 NM_007743
 Col1a2
collagen, type I, alpha 2
chr7_-_17200285 16.482 NM_172739
 Grlf1
glucocorticoid receptor DNA binding factor 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 239 entries
Enrichment   P-value GO Accession GO Term
2.24 4.61e-02 GO:0072006 nephron development
2.17 2.55e-02 GO:0030010 establishment of cell polarity
2.10 8.91e-05 GO:0007163 establishment or maintenance of cell polarity
2.10 3.23e-03 GO:0007269 neurotransmitter secretion
1.81 6.73e-03 GO:0001505 regulation of neurotransmitter levels
1.80 2.90e-02 GO:0045667 regulation of osteoblast differentiation
1.78 1.05e-04 GO:0003001 generation of a signal involved in cell-cell signaling
1.78 1.05e-04 GO:0023061 signal release
1.72 1.87e-03 GO:0031346 positive regulation of cell projection organization
1.63 8.33e-04 GO:0030811 regulation of nucleotide catabolic process
1.63 8.33e-04 GO:0033121 regulation of purine nucleotide catabolic process
1.62 5.70e-03 GO:0043087 regulation of GTPase activity
1.61 8.34e-03 GO:0033124 regulation of GTP catabolic process
1.61 3.49e-02 GO:0001822 kidney development
1.60 4.51e-02 GO:0072001 renal system development
1.57 2.79e-02 GO:0030111 regulation of Wnt receptor signaling pathway
1.54 3.18e-05 GO:0051056 regulation of small GTPase mediated signal transduction
1.53 2.89e-02 GO:0048511 rhythmic process
1.52 4.28e-07 GO:0009894 regulation of catabolic process
1.52 3.52e-02 GO:0042692 muscle cell differentiation

Gene overrepresentation in compartment category:

Showing 1 to 20 of 90 entries
Enrichment   P-value GO Accession GO Term
2.14 9.75e-05 GO:0005913 cell-cell adherens junction
1.96 3.58e-02 GO:0000118 histone deacetylase complex
1.90 1.22e-06 GO:0016327 apicolateral plasma membrane
1.87 4.45e-06 GO:0043296 apical junction complex
1.80 4.02e-04 GO:0005923 tight junction
1.80 4.02e-04 GO:0070160 occluding junction
1.78 6.95e-07 GO:0005912 adherens junction
1.74 1.17e-06 GO:0070161 anchoring junction
1.73 3.46e-03 GO:0014069 postsynaptic density
1.71 1.44e-02 GO:0044309 neuron spine
1.70 1.17e-02 GO:0005925 focal adhesion
1.69 8.47e-03 GO:0030027 lamellipodium
1.68 4.31e-02 GO:0043197 dendritic spine
1.66 1.25e-11 GO:0030425 dendrite
1.66 2.46e-02 GO:0005924 cell-substrate adherens junction
1.64 1.75e-02 GO:0030055 cell-substrate junction
1.63 5.83e-06 GO:0031252 cell leading edge
1.62 6.62e-08 GO:0005911 cell-cell junction
1.60 7.28e-04 GO:0019717 synaptosome
1.58 1.36e-06 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

Showing 1 to 20 of 60 entries
Enrichment   P-value GO Accession GO Term
2.63 7.07e-03 GO:0004407 histone deacetylase activity
2.63 7.07e-03 GO:0033558 protein deacetylase activity
2.59 4.93e-02 GO:0017136 NAD-dependent histone deacetylase activity
2.59 4.93e-02 GO:0034979 NAD-dependent protein deacetylase activity
2.31 4.90e-02 GO:0005520 insulin-like growth factor binding
1.79 1.56e-02 GO:0019902 phosphatase binding
1.71 6.72e-05 GO:0051020 GTPase binding
1.68 2.12e-03 GO:0019838 growth factor binding
1.66 2.58e-03 GO:0031267 small GTPase binding
1.66 6.81e-03 GO:0017016 Ras GTPase binding
1.59 1.21e-07 GO:0005083 small GTPase regulator activity
1.57 4.41e-07 GO:0019901 protein kinase binding
1.56 1.56e-08 GO:0019900 kinase binding
1.54 6.39e-03 GO:0005085 guanyl-nucleotide exchange factor activity
1.52 3.26e-13 GO:0019904 protein domain specific binding
1.51 1.52e-12 GO:0008092 cytoskeletal protein binding
1.51 1.04e-09 GO:0060589 nucleoside-triphosphatase regulator activity
1.51 2.18e-09 GO:0030695 GTPase regulator activity
1.49 3.10e-06 GO:0003779 actin binding
1.47 9.10e-07 GO:0032403 protein complex binding