Motif ID: MTF1.p2

Z-value: 2.688


Transcription factors associated with MTF1.p2:

Gene SymbolEntrez IDGene Name
Mtf1 17764 metal response element binding transcription factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mtf1chr4_+_124479785-0.381.1e-07Click!


Activity profile for motif MTF1.p2.

activity profile for motif MTF1.p2


Sorted Z-values histogram for motif MTF1.p2

Sorted Z-values for motif MTF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MTF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_68298129 64.173 Schip1
schwannomin interacting protein 1
chr15_+_30102306 57.794 NM_008729
 Ctnnd2
catenin (cadherin associated protein), delta 2
chr4_-_151235861 55.054 NM_001081557
NM_001195565
 Camta1

calmodulin binding transcription activator 1

chr11_-_5965743 53.900 NM_001174053
NM_001174054
NM_007595
 Camk2b


calcium/calmodulin-dependent protein kinase II, beta


chr13_+_19040215 51.797 NM_175007
 Amph
amphiphysin
chr8_+_96696677 51.161 Mt2
metallothionein 2
chr8_+_96703145 47.067 Mt1
metallothionein 1
chrX_+_162676870 46.679 NM_001177961
NM_001177962
NM_023122
 Gpm6b


glycoprotein m6b


chr8_+_96696512 43.679 NM_008630
 Mt2
metallothionein 2
chrX_+_53985133 43.038 NM_001077361
 Fhl1
four and a half LIM domains 1
chr4_+_129662110 42.937 Bai2
brain-specific angiogenesis inhibitor 2
chr4_+_148960604 42.694 NM_023051
 Clstn1
calsyntenin 1
chr4_+_129662284 42.628 NM_173071
 Bai2
brain-specific angiogenesis inhibitor 2
chr11_-_5965555 42.135 Camk2b
calcium/calmodulin-dependent protein kinase II, beta
chrX_+_78315963 40.888 NM_138751
 Tmem47
transmembrane protein 47
chr7_+_53651811 39.932 NM_008421
NM_001112739
 Kcnc1

potassium voltage gated channel, Shaw-related subfamily, member 1

chr5_+_34339258 39.795 Nat8l
N-acetyltransferase 8-like
chr11_-_5965544 37.328 Camk2b
calcium/calmodulin-dependent protein kinase II, beta
chrX_+_162676903 37.126 Gpm6b
glycoprotein m6b
chr17_+_25945986 36.347 NM_001164225
 Fbxl16
F-box and leucine-rich repeat protein 16

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 261 entries
Enrichment   P-value GO Accession GO Term
5.73 5.81e-03 GO:0021697 cerebellar cortex formation
4.78 1.89e-02 GO:0007416 synapse assembly
4.42 1.79e-02 GO:0021696 cerebellar cortex morphogenesis
4.20 3.51e-02 GO:0008038 neuron recognition
4.17 1.54e-02 GO:0021795 cerebral cortex cell migration
3.95 2.38e-03 GO:0007431 salivary gland development
3.95 2.38e-03 GO:0030837 negative regulation of actin filament polymerization
3.82 1.36e-05 GO:0007269 neurotransmitter secretion
3.82 1.36e-05 GO:0007270 nerve-nerve synaptic transmission
3.82 2.18e-02 GO:0007435 salivary gland morphogenesis
3.68 3.70e-02 GO:0021587 cerebellum morphogenesis
3.53 1.66e-03 GO:0035272 exocrine system development
3.46 1.18e-03 GO:0048489 synaptic vesicle transport
3.45 4.29e-02 GO:0022029 telencephalon cell migration
3.44 2.64e-03 GO:0021954 central nervous system neuron development
3.41 2.36e-05 GO:0050808 synapse organization
3.38 1.85e-03 GO:0048168 regulation of neuronal synaptic plasticity
3.37 2.99e-02 GO:0021885 forebrain cell migration
3.33 9.23e-03 GO:0048741 skeletal muscle fiber development
3.30 2.06e-02 GO:0032272 negative regulation of protein polymerization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 77 entries
Enrichment   P-value GO Accession GO Term
4.20 1.83e-07 GO:0042734 presynaptic membrane
4.02 2.20e-02 GO:0008328 ionotropic glutamate receptor complex
3.58 1.74e-03 GO:0008287 protein serine/threonine phosphatase complex
3.28 7.57e-09 GO:0030427 site of polarized growth
3.23 6.40e-04 GO:0005905 coated pit
3.21 5.52e-08 GO:0030426 growth cone
3.04 5.65e-07 GO:0014069 postsynaptic density
2.96 1.20e-05 GO:0044309 neuron spine
2.93 2.55e-05 GO:0043197 dendritic spine
2.87 4.41e-02 GO:0031594 neuromuscular junction
2.82 1.88e-02 GO:0005913 cell-cell adherens junction
2.66 7.44e-10 GO:0045211 postsynaptic membrane
2.65 2.23e-18 GO:0030425 dendrite
2.64 5.87e-08 GO:0019717 synaptosome
2.59 1.12e-02 GO:0030117 membrane coat
2.59 1.12e-02 GO:0048475 coated membrane
2.57 1.11e-19 GO:0044456 synapse part
2.55 4.06e-28 GO:0045202 synapse
2.51 5.34e-03 GO:0019897 extrinsic to plasma membrane
2.50 7.66e-09 GO:0031252 cell leading edge

Gene overrepresentation in function category:

Showing 1 to 20 of 61 entries
Enrichment   P-value GO Accession GO Term
5.35 6.56e-06 GO:0035255 ionotropic glutamate receptor binding
4.54 8.64e-07 GO:0035254 glutamate receptor binding
4.25 2.04e-02 GO:0004683 calmodulin-dependent protein kinase activity
3.82 2.91e-02 GO:0005520 insulin-like growth factor binding
3.66 4.92e-02 GO:0005245 voltage-gated calcium channel activity
2.98 4.83e-04 GO:0004714 transmembrane receptor protein tyrosine kinase activity
2.93 4.40e-05 GO:0019199 transmembrane receptor protein kinase activity
2.67 4.09e-07 GO:0005516 calmodulin binding
2.62 1.87e-05 GO:0019838 growth factor binding
2.49 9.27e-04 GO:0030165 PDZ domain binding
2.09 1.13e-02 GO:0004713 protein tyrosine kinase activity
2.06 2.24e-06 GO:0005083 small GTPase regulator activity
2.04 1.69e-07 GO:0003779 actin binding
2.04 1.94e-02 GO:0022843 voltage-gated cation channel activity
2.00 8.66e-10 GO:0060589 nucleoside-triphosphatase regulator activity
2.00 1.67e-09 GO:0030695 GTPase regulator activity
2.00 1.69e-03 GO:0005244 voltage-gated ion channel activity
2.00 1.69e-03 GO:0022832 voltage-gated channel activity
1.93 5.19e-11 GO:0008092 cytoskeletal protein binding
1.93 1.49e-03 GO:0005096 GTPase activator activity