Motif ID: MYB.p2

Z-value: 3.848


Transcription factors associated with MYB.p2:

Gene SymbolEntrez IDGene Name
Myb 17863 myeloblastosis oncogene

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mybchr10_-_208805590.366.4e-07Click!


Activity profile for motif MYB.p2.

activity profile for motif MYB.p2


Sorted Z-values histogram for motif MYB.p2

Sorted Z-values for motif MYB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_83132289 46.315 NM_133948
Psip1
PC4 and SFRS1 interacting protein 1
chr1_-_171461510 38.032 NM_023284
Nuf2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr6_+_116214215 36.917 NM_001081317
Anubl1
AN1, ubiquitin-like, homolog (Xenopus laevis)
chr2_-_37558794 36.548 Strbp
spermatid perinuclear RNA binding protein
chr3_+_40549303 36.509 Hspa4l
heat shock protein 4 like
chr14_-_32064403 35.746 NM_027949
Phf7
PHD finger protein 7
chr2_-_172195998 35.068 NM_011497
Aurka
aurora kinase A
chr9_+_72286335 34.232 NM_008613
Mns1
meiosis-specific nuclear structural protein 1
chr4_-_118109775 34.209 NM_023223
Cdc20
cell division cycle 20 homolog (S. cerevisiae)
chr8_+_86239094 33.880 NM_197982
Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr18_-_46685557 31.960 NM_173423
Fem1c
fem-1 homolog c (C.elegans)
chr19_-_9210094 31.876 Asrgl1
asparaginase like 1
chr2_+_118872854 31.803 NM_029617
Casc5
cancer susceptibility candidate 5
chr18_-_46685512 31.043 Fem1c
fem-1 homolog c (C.elegans)
chr4_-_124614072 30.844 NM_026560
Cdca8
cell division cycle associated 8
chr14_+_47380215 30.756 NM_028222
Cdkn3
cyclin-dependent kinase inhibitor 3
chr1_-_133034721 30.495 NM_145508
Dyrk3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr19_-_9210047 29.791 NM_025610
Asrgl1
asparaginase like 1
chr8_+_85913750 28.949 NM_009904
Clgn
calmegin
chr14_-_66696533 28.731 NM_009618
Adam2
a disintegrin and metallopeptidase domain 2
chr14_+_47380287 28.611 Cdkn3
cyclin-dependent kinase inhibitor 3
chr2_+_17986187 28.339 Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr17_+_8358382 28.314 NM_001197046
NM_201230
Fgfr1op

Fgfr1 oncogene partner

chr16_-_16073490 28.002 2310008H04Rik
RIKEN cDNA 2310008H04 gene
chr18_+_34784277 27.952 NM_001166407
Kif20a
kinesin family member 20A
chr1_-_193399412 27.841 NM_029766
Dtl
denticleless homolog (Drosophila)
chr5_-_31522889 27.722 NM_008014
Ppm1g
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr8_+_86239131 27.692 Ddx39
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
chr9_+_106183391 27.120 NM_027354
Poc1a
POC1 centriolar protein homolog A (Chlamydomonas)
chr2_-_127657532 26.909 NM_001113179
NM_009772
Bub1

budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)

chr7_+_134005943 26.805 Hirip3
HIRA interacting protein 3
chr14_+_70240213 25.912 NM_028526
NM_028560
Pebp4

phosphatidylethanolamine binding protein 4

chr11_+_69749297 25.776 NM_016875
Ybx2
Y box protein 2
chr1_-_44159187 25.752 NM_029368
1700029F09Rik
RIKEN cDNA 1700029F09 gene
chr3_+_116297899 25.714 NM_028349
Sass6
spindle assembly 6 homolog (C. elegans)
chrX_+_130842622 25.623 Cenpi
centromere protein I
chr2_-_126959605 25.622 NM_144818
Ncaph
non-SMC condensin I complex, subunit H
chr5_+_124199713 25.535 NM_001042421
Kntc1
kinetochore associated 1
chr17_-_71200462 25.346 NM_009372
Tgif1
TGFB-induced factor homeobox 1
chr6_+_145564482 25.230 NM_009449
Tuba3b
tubulin, alpha 3B
chrX_+_130842701 25.205 NM_145924
Cenpi
centromere protein I
chr18_+_34784589 24.816 NM_009004
NM_001166406
Kif20a

kinesin family member 20A

chr17_+_31701700 24.752 NM_016670
Pknox1
Pbx/knotted 1 homeobox
chr8_+_86479405 24.727 NM_024184
Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr11_+_23565673 24.491 NM_001033654
NM_028956
Pus10

pseudouridylate synthase 10

chr10_-_22451738 24.109 Tbpl1
TATA box binding protein-like 1
chr3_+_40549475 23.914 NM_011020
Hspa4l
heat shock protein 4 like
chr11_+_23565975 23.206 NM_028304
Pus10
pseudouridylate synthase 10
chr17_-_7165497 23.049 NM_147155
Tagap1
T-cell activation GTPase activating protein 1
chr6_-_125141525 22.957 NM_146171
Ncapd2
non-SMC condensin I complex, subunit D2
chr4_+_140258090 22.612 Rcc2
regulator of chromosome condensation 2
chr10_+_127114119 21.986 NM_001113211
NM_173732
Tmem194

transmembrane protein 194

chr5_+_135625533 21.811 NM_013763
Tbl2
transducin (beta)-like 2
chr4_-_44180323 21.706 NM_175201
Rnf38
ring finger protein 38
chr13_-_26861883 21.290 NM_008232
Hdgfl1
hepatoma derived growth factor-like 1
chr8_+_106774774 21.282 NM_029295
NM_001037841
Cklf

chemokine-like factor

chr5_+_38611707 21.263 NM_025281
Lyar
Ly1 antibody reactive clone
chr11_+_87430665 21.251 NM_001045527
Hsf5
heat shock transcription factor family member 5
chr2_+_118639930 21.229 D2Ertd750e
DNA segment, Chr 2, ERATO Doi 750, expressed
chr12_-_80292805 21.220 NM_021557
Rdh11
retinol dehydrogenase 11
chr2_+_118639738 20.996 NM_026412
D2Ertd750e
DNA segment, Chr 2, ERATO Doi 750, expressed
chr1_+_58052814 20.405 NM_199007
Sgol2
shugoshin-like 2 (S. pombe)
chr5_-_8422533 20.212 NM_001190717
NM_013726
Dbf4

DBF4 homolog (S. cerevisiae)

chr17_-_34027575 19.371 NM_001195298
Kifc1
kinesin family member C1
chr11_+_105043195 19.302 Tlk2
tousled-like kinase 2 (Arabidopsis)
chr11_+_102526898 19.134 NM_001127576
Gm1564
predicted gene 1564
chr9_+_20833816 18.648 NM_023892
Icam4
intercellular adhesion molecule 4, Landsteiner-Wiener blood group
chr17_-_34027488 18.509 Kifc1
kinesin family member C1
chr1_-_193399352 18.392 Dtl
denticleless homolog (Drosophila)
chr2_-_164860272 18.239 NM_144892
Ncoa5
nuclear receptor coactivator 5
chr12_-_80292830 18.229 Rdh11
retinol dehydrogenase 11
chr11_+_83116262 18.196 Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr10_-_119913990 18.101 NM_010441
Hmga2
high mobility group AT-hook 2
chr6_-_146902928 17.940 NM_001164236
NM_028509
1700034J05Rik

RIKEN cDNA 1700034J05 gene

chr2_-_144156799 17.579 Ovol2
ovo-like 2 (Drosophila)
chr7_-_52689639 17.578 Ruvbl2
RuvB-like protein 2
chr4_+_129168433 17.515 NM_001085491
1700125D06Rik
RIKEN cDNA 1700125D06 gene
chr18_+_56867378 17.351 NM_010721
Lmnb1
lamin B1
chr11_-_105042428 17.294 1700052K11Rik
RIKEN cDNA 1700052K11 gene
chr19_-_29399819 17.152 Insl6
insulin-like 6
chr1_-_168168870 17.110 NM_175296
Mael
maelstrom homolog (Drosophila)
chr12_+_66326503 17.064 NM_027614
Wdr20b
WD repeat domain 20b
chr5_-_31522802 16.968 Ppm1g
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr17_-_34027547 16.898 Kifc1
kinesin family member C1
chr6_+_8459595 16.836 NM_133236
Glcci1
glucocorticoid induced transcript 1
chr1_-_158233462 16.812 NM_001134741
Tdrd5
tudor domain containing 5
chr6_-_88834347 16.731 Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr2_-_121239527 16.539 NM_153075
Catsper2
cation channel, sperm associated 2
chr7_-_17509228 16.523 NM_007590
Calm3
calmodulin 3
chr11_+_62875160 16.362 NM_027660
Tekt3
tektin 3
chr14_-_87540995 16.218 Diap3
diaphanous homolog 3 (Drosophila)
chr6_-_28211600 16.159 NM_001081678
Zfp800
zinc finger protein 800
chr19_-_29399804 16.150 NM_013754
Insl6
insulin-like 6
chr5_+_34001199 16.143 Tacc3
transforming, acidic coiled-coil containing protein 3
chr12_-_92622769 16.137 NM_181815
4930534B04Rik
RIKEN cDNA 4930534B04 gene
chr6_-_28211910 16.015 Zfp800
zinc finger protein 800
chr1_-_158869650 15.984 NM_001159965
NM_001159967
NM_001159968
NM_023884
Ralgps2



Ral GEF with PH domain and SH3 binding motif 2



chr2_-_144157097 15.892 NM_152947
Ovol2
ovo-like 2 (Drosophila)
chr5_+_3657003 15.781 NM_029141
NM_029154
4930511M11Rik

RIKEN cDNA 4930511M11 gene

chr10_+_79689342 15.745 NM_023431
Mum1
melanoma associated antigen (mutated) 1
chr7_+_13610047 15.741 Trim28
tripartite motif-containing 28
chr3_+_146067763 15.593 Ssx2ip
synovial sarcoma, X breakpoint 2 interacting protein
chr8_-_25836259 15.587 NM_009619
Adam3
a disintegrin and metallopeptidase domain 3 (cyritestin)
chr7_+_134005485 15.540 NM_172746
Hirip3
HIRA interacting protein 3
chrX_+_97821403 15.482 NM_008446
Kif4
kinesin family member 4
chr2_-_3336293 15.242 Meig1
meiosis expressed gene 1
chr3_+_146067605 15.158 NM_138744
Ssx2ip
synovial sarcoma, X breakpoint 2 interacting protein
chr6_+_136467388 15.111 Atf7ip
activating transcription factor 7 interacting protein
chr9_+_107449628 15.108 NM_053253
Zmynd10
zinc finger, MYND domain containing 10
chr9_-_35365985 15.097 NM_013932
Ddx25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr7_+_52071438 15.026 Nup62
nucleoporin 62
chr11_-_33413625 14.921 Ranbp17
RAN binding protein 17
chr3_-_51144470 14.829 Elf2
E74-like factor 2
chr1_-_158869401 14.710 NM_001159966
Ralgps2
Ral GEF with PH domain and SH3 binding motif 2
chr1_+_193645351 14.694 NM_010892
Nek2
NIMA (never in mitosis gene a)-related expressed kinase 2
chr15_-_103260834 14.638 NM_028797
Gtsf1
gametocyte specific factor 1
chr8_+_73118329 14.624 NM_023627
Isyna1
myo-inositol 1-phosphate synthase A1
chr6_+_89594017 14.617 Txnrd3
thioredoxin reductase 3
chr7_+_52071622 14.534 NM_001171024
NM_053074
Nup62-il4i1
Nup62
Nup62-Il4i1 protein
nucleoporin 62
chrX_+_20002809 14.517 Phf16
PHD finger protein 16
chr11_+_62660624 14.499 NM_001033669
Fbxw10
F-box and WD-40 domain protein 10
chr4_-_43512476 14.490 NM_001013377
E130306D19Rik
RIKEN cDNA E130306D19 gene
chr6_+_54766562 14.460 NM_199143
Znrf2
zinc and ring finger 2
chr10_-_88906629 14.430 NM_001033331
NM_001079876
Gas2l3

growth arrest-specific 2 like 3

chr19_+_36484237 14.386 Pcgf5
polycomb group ring finger 5
chr17_+_47736273 14.255 Ccnd3
cyclin D3
chr2_+_122463622 14.218 NM_001004174
AA467197
expressed sequence AA467197
chr7_-_52689833 14.191 NM_011304
Ruvbl2
RuvB-like protein 2
chr14_+_56364551 14.153 2610027L16Rik
RIKEN cDNA 2610027L16 gene
chr6_+_89593981 14.089 NM_001178058
NM_001178059
NM_001178060
NM_153162
Txnrd3



thioredoxin reductase 3



chr7_-_104886507 14.074 Aqp11
aquaporin 11
chr14_+_56364519 14.071 NM_026403
2610027L16Rik
RIKEN cDNA 2610027L16 gene
chr3_+_137527448 14.051 NM_016750
H2afz
H2A histone family, member Z
chr11_+_100575163 14.042 NM_029307
Hspb9
heat shock protein, alpha-crystallin-related, B9
chr7_+_29225955 14.021 NM_001039192
Gmfg
glia maturation factor, gamma
chr3_+_40512792 14.014 NM_178386
Slc25a31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr2_-_164860303 13.975 Ncoa5
nuclear receptor coactivator 5
chr2_-_119303348 13.863 NM_026574
Ino80
INO80 homolog (S. cerevisiae)
chr6_-_113327472 13.860 NM_133932
Tada3
transcriptional adaptor 3
chr14_+_35487052 13.804 NM_001004436
Wapal
wings apart-like homolog (Drosophila)
chr4_-_107356766 13.761 NM_019872
Dmrtb1
DMRT-like family B with proline-rich C-terminal, 1
chr13_+_22073049 13.737 NM_001162928
NM_001162929
Pom121l2

POM121 membrane glycoprotein-like 2 (rat)

chr11_+_105043224 13.723 Tlk2
tousled-like kinase 2 (Arabidopsis)
chr4_-_116855158 13.539 NM_134471
Kif2c
kinesin family member 2C
chr1_-_163806710 13.509 NM_172645
AI848100
expressed sequence AI848100
chr5_-_123439064 13.473 NM_001003953
Kdm2b
lysine (K)-specific demethylase 2B
chr18_-_70689894 13.470 NM_011972
Poli
polymerase (DNA directed), iota
chr9_+_108295164 13.420 NM_053216
1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr3_-_68930721 13.391 Kpna4
karyopherin (importin) alpha 4
chr1_+_75139300 13.350 NM_170755
Fam134a
family with sequence similarity 134, member A
chr15_+_4848736 13.341 NM_001166066
Heatr7b2
XVHEAT repeat family member 7B2
chr16_+_36935029 13.333 NM_008225
Hcls1
hematopoietic cell specific Lyn substrate 1
chr19_-_41876509 13.296 NM_001163495
NM_027667
Arhgap19

Rho GTPase activating protein 19

chr6_+_136467315 13.291 NM_019426
Atf7ip
activating transcription factor 7 interacting protein
chr10_-_22451093 13.240 Tbpl1
TATA box binding protein-like 1
chr6_-_131338465 13.229 NM_011733
NM_139117
Csda

cold shock domain protein A

chr1_+_40497472 13.213 NM_001025602
Il1rl1
interleukin 1 receptor-like 1
chr1_-_60155312 13.203 NM_001199060
Wdr12
WD repeat domain 12
chr4_-_116300533 13.160 NM_016777
Nasp
nuclear autoantigenic sperm protein (histone-binding)
chr18_-_25327116 12.945 5730494M16Rik
RIKEN cDNA 5730494M16 gene
chr3_+_137527575 12.838 H2afz
H2A histone family, member Z
chr12_+_34000269 12.828 Atxn7l1
ataxin 7-like 1
chr12_-_70299271 12.809 NM_027269
1110034A24Rik
RIKEN cDNA 1110034A24 gene
chr15_-_36538484 12.806 Pabpc1
poly(A) binding protein, cytoplasmic 1
chr11_-_82577789 12.778 NM_009839
Cct6b
chaperonin containing Tcp1, subunit 6b (zeta)
chr9_+_30838224 12.727 NM_001115130
NM_172765
Zbtb44

zinc finger and BTB domain containing 44

chr5_-_125342474 12.666 NM_144819
Ccdc92
coiled-coil domain containing 92
chr7_-_134169938 12.632 NM_010772
Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chrX_-_99352341 12.626 NM_146235
Ercc6l
excision repair cross-complementing rodent repair deficiency complementation group 6 - like
chr8_-_25785199 12.623 NM_010084
Adam18
a disintegrin and metallopeptidase domain 18
chr14_-_63379948 12.581 NM_008715
Ints6
integrator complex subunit 6
chr2_+_172196428 12.555 NM_024199
Cstf1
cleavage stimulation factor, 3' pre-RNA, subunit 1
chr8_-_75072164 12.529 NM_027485
Med26
mediator complex subunit 26
chr17_-_71876127 12.525 Ndc80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr5_+_7304126 12.525 NM_027603
4921511H03Rik
RIKEN cDNA 4921511H03 gene
chr6_-_113327369 12.492 Tada3
transcriptional adaptor 3
chr1_-_55419550 12.486 NM_001113367
Boll
bol, boule-like (Drosophila)
chr12_-_85489188 12.472 NM_027438
Pnma1
paraneoplastic antigen MA1
chr15_-_83749802 12.456 NM_001161629
Efcab6
EF-hand calcium binding domain 6
chr18_-_34911152 12.454 NM_009860
Cdc25c
cell division cycle 25 homolog C (S. pombe)
chr11_+_23156482 12.438 Xpo1
exportin 1, CRM1 homolog (yeast)
chr15_+_57743727 12.437 NM_001081396
NM_001167679
Wdr67

WD repeat domain 67

chr14_-_99498905 12.428 NM_028315
Dis3
DIS3 mitotic control homolog (S. cerevisiae)
chr17_-_9862538 12.406 NM_001163836
Pabpc6
poly(A) binding protein, cytoplasmic 6
chr2_+_53050461 12.243 Arl6ip6
ADP-ribosylation factor-like 6 interacting protein 6
chr2_-_72817311 12.219 NM_001098425
Sp3
trans-acting transcription factor 3
chr8_+_86132073 12.213 NM_018808
Dnajb1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr11_+_97223851 12.184 NM_138657
Socs7
suppressor of cytokine signaling 7
chr15_+_89398756 12.115 NM_013455
Acr
acrosin prepropeptide
chr9_-_62129985 12.081 NM_025721
Spesp1
sperm equatorial segment protein 1
chr11_-_78364173 12.038 NM_133706
Tmem97
transmembrane protein 97
chr13_-_101556356 12.030 NM_172301
Ccnb1
cyclin B1
chrX_+_20002875 12.027 Phf16
PHD finger protein 16
chr3_+_40512853 11.983 Slc25a31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr1_-_75139207 11.903 1810031K17Rik
RIKEN cDNA 1810031K17 gene
chr18_-_70689871 11.798 Poli
polymerase (DNA directed), iota
chr7_+_135056028 11.788 NM_026370
Myst1
MYST histone acetyltransferase 1
chr2_-_25127860 11.783 NM_023464
Ssna1
Sjogren's syndrome nuclear autoantigen 1
chr2_+_125977876 11.747 NM_026981
Dtwd1
DTW domain containing 1
chr11_-_68740550 11.731 NM_145746
Odf4
outer dense fiber of sperm tails 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.59 2.04e-33 GO:0044260 cellular macromolecule metabolic process
1.51 4.03e-29 GO:0043170 macromolecule metabolic process
1.76 6.15e-27 GO:0090304 nucleic acid metabolic process
1.81 3.22e-25 GO:0016070 RNA metabolic process
1.70 1.84e-21 GO:0010467 gene expression
1.60 5.96e-21 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.70 1.17e-20 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.66 6.22e-20 GO:0010468 regulation of gene expression
1.67 2.18e-19 GO:0010556 regulation of macromolecule biosynthetic process
1.35 6.94e-19 GO:0044238 primary metabolic process
1.63 1.14e-18 GO:0031326 regulation of cellular biosynthetic process
1.36 1.62e-18 GO:0044237 cellular metabolic process
1.54 5.44e-18 GO:0060255 regulation of macromolecule metabolic process
1.68 7.01e-18 GO:0051252 regulation of RNA metabolic process
1.61 1.01e-17 GO:0009889 regulation of biosynthetic process
1.52 1.27e-17 GO:0031323 regulation of cellular metabolic process
1.68 1.83e-17 GO:0006355 regulation of transcription, DNA-dependent
1.52 1.86e-17 GO:0080090 regulation of primary metabolic process
1.66 2.37e-17 GO:0009059 macromolecule biosynthetic process
1.66 2.42e-17 GO:0034645 cellular macromolecule biosynthetic process
1.61 3.44e-17 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.51 4.20e-17 GO:0034641 cellular nitrogen compound metabolic process
1.60 5.49e-17 GO:0051171 regulation of nitrogen compound metabolic process
1.79 6.54e-17 GO:0006351 transcription, DNA-dependent
1.79 8.32e-17 GO:0032774 RNA biosynthetic process
1.50 1.92e-16 GO:0006807 nitrogen compound metabolic process
1.44 8.12e-15 GO:0019222 regulation of metabolic process
2.15 1.13e-14 GO:0007049 cell cycle
2.63 2.24e-14 GO:0022403 cell cycle phase
1.80 1.13e-13 GO:0006996 organelle organization
2.34 1.39e-13 GO:0022402 cell cycle process
2.70 4.17e-12 GO:0000279 M phase
2.66 2.32e-11 GO:0051301 cell division
1.25 2.86e-11 GO:0008152 metabolic process
1.56 5.92e-11 GO:0044267 cellular protein metabolic process
1.45 2.03e-10 GO:0044249 cellular biosynthetic process
2.48 2.30e-10 GO:0000278 mitotic cell cycle
2.93 5.94e-10 GO:0048285 organelle fission
1.55 6.91e-10 GO:0071842 cellular component organization at cellular level
2.92 1.01e-09 GO:0000087 M phase of mitotic cell cycle
2.93 1.41e-09 GO:0000280 nuclear division
2.93 1.41e-09 GO:0007067 mitosis
1.42 1.70e-09 GO:0009058 biosynthetic process
1.52 1.77e-09 GO:0071841 cellular component organization or biogenesis at cellular level
2.15 2.88e-08 GO:0051276 chromosome organization
2.43 4.77e-08 GO:0016568 chromatin modification
1.57 8.25e-08 GO:0006464 protein modification process
1.42 1.10e-07 GO:0019538 protein metabolic process
2.29 1.50e-07 GO:0006325 chromatin organization
1.54 2.40e-07 GO:0043412 macromolecule modification
1.90 4.10e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.85 6.80e-07 GO:0031327 negative regulation of cellular biosynthetic process
2.48 8.45e-07 GO:0007283 spermatogenesis
2.48 8.45e-07 GO:0048232 male gamete generation
2.43 8.47e-07 GO:0018193 peptidyl-amino acid modification
2.79 1.21e-06 GO:0016570 histone modification
1.87 1.43e-06 GO:0010629 negative regulation of gene expression
1.84 1.93e-06 GO:0010558 negative regulation of macromolecule biosynthetic process
2.74 2.06e-06 GO:0016569 covalent chromatin modification
1.80 2.71e-06 GO:0009890 negative regulation of biosynthetic process
1.69 3.41e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.37 5.15e-06 GO:0016043 cellular component organization
1.83 8.75e-06 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.82 9.53e-06 GO:0051172 negative regulation of nitrogen compound metabolic process
1.86 1.14e-05 GO:0051253 negative regulation of RNA metabolic process
1.35 1.37e-05 GO:0071840 cellular component organization or biogenesis
1.62 2.37e-05 GO:0009892 negative regulation of metabolic process
1.65 3.18e-05 GO:0031324 negative regulation of cellular metabolic process
2.13 3.94e-05 GO:0016071 mRNA metabolic process
1.83 4.90e-05 GO:0045892 negative regulation of transcription, DNA-dependent
3.24 7.12e-05 GO:0018205 peptidyl-lysine modification
3.62 7.83e-05 GO:0050657 nucleic acid transport
3.62 7.83e-05 GO:0050658 RNA transport
3.62 7.83e-05 GO:0051236 establishment of RNA localization
4.28 1.40e-04 GO:0051168 nuclear export
3.49 1.73e-04 GO:0006403 RNA localization
1.83 3.44e-04 GO:0006396 RNA processing
2.03 3.88e-04 GO:0007276 gamete generation
3.42 4.81e-04 GO:0006473 protein acetylation
3.54 4.85e-04 GO:0018394 peptidyl-lysine acetylation
3.20 5.44e-04 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.12 9.46e-04 GO:0006397 mRNA processing
3.51 1.05e-03 GO:0016573 histone acetylation
3.51 1.05e-03 GO:0051028 mRNA transport
2.23 1.24e-03 GO:0007017 microtubule-based process
1.84 1.50e-03 GO:0032504 multicellular organism reproduction
1.84 1.50e-03 GO:0048609 multicellular organismal reproductive process
3.42 1.75e-03 GO:0006475 internal protein amino acid acetylation
3.42 1.75e-03 GO:0018393 internal peptidyl-lysine acetylation
2.17 1.98e-03 GO:0010608 posttranscriptional regulation of gene expression
2.60 2.46e-03 GO:0006913 nucleocytoplasmic transport
1.87 2.67e-03 GO:0019953 sexual reproduction
3.03 2.70e-03 GO:0043543 protein acylation
2.54 3.93e-03 GO:0051169 nuclear transport
1.53 5.63e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.41 8.84e-03 GO:0000226 microtubule cytoskeleton organization
1.25 1.41e-02 GO:0032502 developmental process
2.01 1.67e-02 GO:0008380 RNA splicing
1.32 2.14e-02 GO:0048523 negative regulation of cellular process
1.33 2.31e-02 GO:0048869 cellular developmental process
3.03 3.89e-02 GO:0006479 protein methylation
3.03 3.89e-02 GO:0008213 protein alkylation
1.29 4.54e-02 GO:0048519 negative regulation of biological process
1.75 4.61e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.67 4.77e-48 GO:0005634 nucleus
1.29 2.16e-35 GO:0005622 intracellular
1.28 1.08e-31 GO:0044424 intracellular part
1.32 8.30e-30 GO:0043229 intracellular organelle
1.32 2.94e-29 GO:0043226 organelle
1.34 5.13e-28 GO:0043231 intracellular membrane-bounded organelle
1.34 1.15e-27 GO:0043227 membrane-bounded organelle
1.83 2.58e-20 GO:0044428 nuclear part
1.86 4.75e-17 GO:0031981 nuclear lumen
1.42 2.05e-14 GO:0044446 intracellular organelle part
1.41 3.65e-14 GO:0044422 organelle part
1.95 1.14e-13 GO:0005654 nucleoplasm
1.47 1.15e-13 GO:0032991 macromolecular complex
1.67 1.98e-12 GO:0070013 intracellular organelle lumen
1.67 2.43e-12 GO:0043233 organelle lumen
1.65 6.17e-12 GO:0031974 membrane-enclosed lumen
1.48 9.22e-12 GO:0043234 protein complex
2.07 4.30e-11 GO:0044451 nucleoplasm part
1.46 1.04e-08 GO:0043228 non-membrane-bounded organelle
1.46 1.04e-08 GO:0043232 intracellular non-membrane-bounded organelle
2.00 5.39e-08 GO:0015630 microtubule cytoskeleton
2.13 2.66e-07 GO:0044427 chromosomal part
2.08 2.99e-07 GO:0005694 chromosome
3.05 1.08e-06 GO:0000775 chromosome, centromeric region
3.98 8.13e-06 GO:0000123 histone acetyltransferase complex
1.15 1.01e-04 GO:0005737 cytoplasm
3.24 1.22e-04 GO:0000776 kinetochore
2.62 3.47e-04 GO:0016604 nuclear body
2.25 5.21e-04 GO:0000785 chromatin
1.55 5.94e-04 GO:0044430 cytoskeletal part
2.19 7.53e-04 GO:0005815 microtubule organizing center
3.46 8.25e-04 GO:0000792 heterochromatin
2.07 9.66e-04 GO:0005874 microtubule
2.17 2.44e-03 GO:0000228 nuclear chromosome
4.41 2.68e-03 GO:0035770 RNA granule
2.18 2.75e-03 GO:0005813 centrosome
1.39 3.45e-03 GO:0005856 cytoskeleton
2.21 4.97e-03 GO:0044454 nuclear chromosome part
1.68 1.15e-02 GO:0030529 ribonucleoprotein complex
2.63 1.40e-02 GO:0000790 nuclear chromatin
2.69 3.49e-02 GO:0016585 chromatin remodeling complex
4.36 4.28e-02 GO:0070461 SAGA-type complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.67 6.58e-21 GO:0003676 nucleic acid binding
1.18 5.02e-12 GO:0005488 binding
2.08 5.75e-12 GO:0003723 RNA binding
1.55 8.57e-09 GO:0003677 DNA binding
1.63 2.47e-08 GO:0008270 zinc ion binding
1.77 6.62e-08 GO:0030528 transcription regulator activity
1.43 1.43e-06 GO:0000166 nucleotide binding
1.23 1.89e-06 GO:0005515 protein binding
1.44 7.65e-05 GO:0046914 transition metal ion binding
2.26 1.41e-04 GO:0003712 transcription cofactor activity
2.25 1.60e-04 GO:0000989 transcription factor binding transcription factor activity
1.46 1.70e-04 GO:0005524 ATP binding
1.41 1.88e-04 GO:0035639 purine ribonucleoside triphosphate binding
2.05 2.23e-04 GO:0016564 transcription repressor activity
2.22 2.30e-04 GO:0000988 protein binding transcription factor activity
1.39 4.33e-04 GO:0017076 purine nucleotide binding
1.44 4.59e-04 GO:0030554 adenyl nucleotide binding
1.39 4.96e-04 GO:0032555 purine ribonucleotide binding
1.39 5.17e-04 GO:0032553 ribonucleotide binding
1.44 5.29e-04 GO:0032559 adenyl ribonucleotide binding
1.84 1.56e-03 GO:0004674 protein serine/threonine kinase activity
2.51 1.79e-03 GO:0003713 transcription coactivator activity
2.21 2.17e-03 GO:0003682 chromatin binding
1.57 1.22e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.61 1.88e-02 GO:0004672 protein kinase activity
1.49 1.92e-02 GO:0019899 enzyme binding
1.45 3.17e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups