Motif ID: MYBL2.p2

Z-value: 1.142


Transcription factors associated with MYBL2.p2:

Gene SymbolEntrez IDGene Name
Mybl2 17865 myeloblastosis oncogene-like 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mybl2chr2_+_162880370-0.401.4e-08Click!


Activity profile for motif MYBL2.p2.

activity profile for motif MYBL2.p2


Sorted Z-values histogram for motif MYBL2.p2

Sorted Z-values for motif MYBL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYBL2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_104543106 21.059 NM_010097
 Sparcl1
SPARC-like 1
chr13_+_49704471 18.717 Ogn
osteoglycin
chr16_+_35002066 13.966 Mylk
myosin, light polypeptide kinase
chr11_+_93905443 12.478 Spag9
sperm associated antigen 9
chr6_+_70676428 12.473


chr13_+_83803830 11.751 Mef2c
myocyte enhancer factor 2C
chr11_+_87607531 11.364 Mpo
myeloperoxidase
chr16_+_96422243 11.089 Sh3bgr
SH3-binding domain glutamic acid-rich protein
chr11_+_87607285 10.710 NM_010824
 Mpo
myeloperoxidase
chr11_+_93905557 10.568 Spag9
sperm associated antigen 9
chr4_-_60594496 10.201 Mup1
major urinary protein 1
chr4_-_60889249 9.959 NM_001134674
 Mup13
Mup19
Mup1
major urinary protein 13
major urinary protein 19
major urinary protein 1
chr4_-_60594469 9.716 Mup1
major urinary protein 1
chrX_+_54032858 9.573 NM_001077362
 Fhl1
four and a half LIM domains 1
chr2_+_103798150 9.494 NM_001142337
 Lmo2
LIM domain only 2
chr4_+_138012860 9.261 Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr16_+_96422076 9.201 NM_015825
 Sh3bgr
SH3-binding domain glutamic acid-rich protein
chr16_+_35001358 8.902 Mylk
myosin, light polypeptide kinase
chr6_-_60779848 8.699 NM_009221
 Snca
synuclein, alpha
chrX_+_54032914 8.674 Fhl1
four and a half LIM domains 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
Enrichment   P-value GO Accession GO Term
7.82 1.04e-02 GO:0032272 negative regulation of protein polymerization
6.78 9.56e-03 GO:0031333 negative regulation of protein complex assembly
6.48 4.47e-04 GO:0051494 negative regulation of cytoskeleton organization
4.52 4.35e-03 GO:0010639 negative regulation of organelle organization
3.95 4.33e-02 GO:0010466 negative regulation of peptidase activity
2.32 2.63e-03 GO:0022610 biological adhesion
2.27 5.52e-03 GO:0007155 cell adhesion
1.77 5.45e-03 GO:0051239 regulation of multicellular organismal process
1.66 3.86e-02 GO:0048583 regulation of response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
4.33 1.15e-03 GO:0044420 extracellular matrix part
4.33 1.23e-02 GO:0030017 sarcomere
4.14 8.82e-03 GO:0044449 contractile fiber part
3.81 1.99e-02 GO:0030016 myofibril
3.79 1.05e-02 GO:0043292 contractile fiber
3.31 2.69e-05 GO:0005578 proteinaceous extracellular matrix
2.91 3.25e-04 GO:0031012 extracellular matrix
2.71 1.03e-02 GO:0015629 actin cytoskeleton
2.43 1.05e-03 GO:0045202 synapse
2.02 7.10e-03 GO:0005615 extracellular space
1.96 1.28e-03 GO:0044421 extracellular region part
1.81 1.09e-05 GO:0005576 extracellular region
1.44 5.57e-04 GO:0071944 cell periphery
1.44 7.89e-04 GO:0005886 plasma membrane
1.20 2.99e-02 GO:0005737 cytoplasm
1.15 3.40e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 20 of 24 entries
Enrichment   P-value GO Accession GO Term
21.71 3.07e-05 GO:0004522 pancreatic ribonuclease activity
18.09 1.29e-04 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters
12.77 1.53e-03 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters
6.67 2.63e-02 GO:0004521 endoribonuclease activity
5.71 8.99e-03 GO:0004540 ribonuclease activity
4.47 2.86e-02 GO:0008017 microtubule binding
4.14 1.23e-02 GO:0004867 serine-type endopeptidase inhibitor activity
3.90 4.42e-02 GO:0008201 heparin binding
3.88 3.67e-04 GO:0030414 peptidase inhibitor activity
3.87 7.53e-04 GO:0004866 endopeptidase inhibitor activity
3.81 1.84e-03 GO:0001871 pattern binding
3.81 1.84e-03 GO:0030247 polysaccharide binding
3.73 1.26e-03 GO:0061135 endopeptidase regulator activity
3.73 9.17e-03 GO:0005539 glycosaminoglycan binding
3.44 3.19e-05 GO:0004857 enzyme inhibitor activity
3.32 3.31e-03 GO:0061134 peptidase regulator activity
3.14 1.10e-04 GO:0003779 actin binding
2.93 3.25e-07 GO:0008092 cytoskeletal protein binding
2.44 7.78e-03 GO:0060589 nucleoside-triphosphatase regulator activity
2.42 1.25e-02 GO:0030695 GTPase regulator activity