Motif ID: MYFfamily.p2

Z-value: 1.973


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
Myf5 17877 myogenic factor 5
Myf6 17878 myogenic factor 6
Myod1 17927 myogenic differentiation 1
Myog 17928 myogenin

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Myf5chr10_-_106922986-0.272.0e-04Click!
Myod1chr7_+_53631843-0.154.5e-02Click!
Myogchr1_+_136186579-0.101.9e-01Click!
Myf6chr10_-_106931783-0.064.0e-01Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_119510890 63.551 NM_138742
 Nap1l3
nucleosome assembly protein 1-like 3
chr8_-_9771020 52.359 NM_173446
 Fam155a
family with sequence similarity 155, member A
chr9_-_112088452 40.676 NM_001177618
 Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr2_+_83652846 35.894 NM_175514
 Fam171b
family with sequence similarity 171, member B
chr4_+_104829951 30.944 NM_080555
 Ppap2b
phosphatidic acid phosphatase type 2B
chr18_+_45719732 29.479 NM_080465
 Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr4_+_104829963 28.668 Ppap2b
phosphatidic acid phosphatase type 2B
chr9_+_75473524 27.256 NM_027309
 Lysmd2
LysM, putative peptidoglycan-binding, domain containing 2
chr2_+_48805027 26.314 NM_029924
 Mbd5
methyl-CpG binding domain protein 5
chr12_-_73509668 25.503 Rtn1
reticulon 1
chr6_-_77929543 24.716 Ctnna2
catenin (cadherin associated protein), alpha 2
chr2_+_157387284 23.863 Nnat
neuronatin
chr4_+_104830022 23.681 Ppap2b
phosphatidic acid phosphatase type 2B
chr18_+_45719464 23.458 Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr6_-_77929685 23.375 Ctnna2
catenin (cadherin associated protein), alpha 2
chr17_+_35373506 23.325 NM_023179
 Atp6v1g2
ATPase, H+ transporting, lysosomal V1 subunit G2
chr12_-_71448600 23.250 NM_001110202
NM_001110203
NM_053167
 Trim9


tripartite motif-containing 9


chr9_+_27598853 23.020 NM_177906
 Opcml
opioid binding protein/cell adhesion molecule-like
chr6_-_126690651 22.792 NM_013568
 Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr12_-_73509537 22.481 Rtn1
reticulon 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 115 entries
Enrichment   P-value GO Accession GO Term
3.81 4.51e-04 GO:0010464 regulation of mesenchymal cell proliferation
3.66 9.69e-03 GO:0048814 regulation of dendrite morphogenesis
3.55 1.54e-02 GO:0046928 regulation of neurotransmitter secretion
3.47 1.25e-03 GO:0050773 regulation of dendrite development
3.45 2.38e-02 GO:0002053 positive regulation of mesenchymal cell proliferation
3.11 3.19e-02 GO:0007269 neurotransmitter secretion
2.98 2.08e-03 GO:0070588 calcium ion transmembrane transport
2.76 9.92e-03 GO:0017157 regulation of exocytosis
2.56 9.02e-08 GO:0010975 regulation of neuron projection development
2.54 3.17e-02 GO:0001505 regulation of neurotransmitter levels
2.53 1.02e-02 GO:0050770 regulation of axonogenesis
2.44 2.10e-02 GO:0031589 cell-substrate adhesion
2.33 2.76e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.33 2.76e-04 GO:0022604 regulation of cell morphogenesis
2.32 1.87e-06 GO:0031344 regulation of cell projection organization
2.25 5.30e-08 GO:0007268 synaptic transmission
2.22 1.83e-04 GO:0043062 extracellular structure organization
2.22 1.14e-02 GO:0007611 learning or memory
2.21 6.98e-03 GO:0050890 cognition
2.19 1.33e-07 GO:0045664 regulation of neuron differentiation

Gene overrepresentation in compartment category:

Showing 1 to 20 of 62 entries
Enrichment   P-value GO Accession GO Term
5.63 1.94e-02 GO:0060053 neurofilament cytoskeleton
4.60 6.60e-04 GO:0034704 calcium channel complex
3.71 1.19e-02 GO:0005581 collagen
3.13 2.65e-02 GO:0005795 Golgi stack
2.97 9.44e-03 GO:0043195 terminal button
2.90 6.16e-10 GO:0019717 synaptosome
2.87 1.49e-04 GO:0043197 dendritic spine
2.79 2.73e-04 GO:0044309 neuron spine
2.68 1.60e-07 GO:0033267 axon part
2.68 6.46e-04 GO:0043679 axon terminus
2.61 5.69e-06 GO:0044420 extracellular matrix part
2.59 9.09e-04 GO:0030427 site of polarized growth
2.59 9.09e-04 GO:0044306 neuron projection terminus
2.58 1.44e-03 GO:0030426 growth cone
2.56 3.23e-18 GO:0044456 synapse part
2.52 3.07e-04 GO:0008021 synaptic vesicle
2.52 2.40e-03 GO:0014069 postsynaptic density
2.48 2.43e-02 GO:0031227 intrinsic to endoplasmic reticulum membrane
2.40 1.00e-03 GO:0034703 cation channel complex
2.37 5.65e-12 GO:0030425 dendrite

Gene overrepresentation in function category:

Showing 1 to 20 of 40 entries
Enrichment   P-value GO Accession GO Term
3.00 8.57e-04 GO:0004714 transmembrane receptor protein tyrosine kinase activity
2.76 1.02e-03 GO:0019199 transmembrane receptor protein kinase activity
2.57 1.02e-02 GO:0005262 calcium channel activity
2.45 7.06e-04 GO:0019838 growth factor binding
2.42 1.46e-04 GO:0005516 calmodulin binding
2.24 2.73e-08 GO:0005261 cation channel activity
2.21 2.33e-03 GO:0022843 voltage-gated cation channel activity
2.18 2.80e-02 GO:0015276 ligand-gated ion channel activity
2.18 2.80e-02 GO:0022834 ligand-gated channel activity
2.13 5.93e-03 GO:0005539 glycosaminoglycan binding
2.10 3.88e-04 GO:0005244 voltage-gated ion channel activity
2.10 3.88e-04 GO:0022832 voltage-gated channel activity
2.08 5.59e-07 GO:0022836 gated channel activity
2.08 3.26e-02 GO:0005267 potassium channel activity
2.06 5.65e-03 GO:0001871 pattern binding
2.06 5.65e-03 GO:0030247 polysaccharide binding
1.98 7.21e-08 GO:0005216 ion channel activity
1.94 2.42e-07 GO:0022838 substrate-specific channel activity
1.89 2.61e-09 GO:0005509 calcium ion binding
1.88 1.35e-06 GO:0015267 channel activity