Motif ID: NANOG.p2

Z-value: 0.953


Transcription factors associated with NANOG.p2:

Gene SymbolEntrez IDGene Name
Nanog 71950 Nanog homeobox

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nanogchr6_+_1226575060.223.5e-03Click!


Activity profile for motif NANOG.p2.

activity profile for motif NANOG.p2


Sorted Z-values histogram for motif NANOG.p2

Sorted Z-values for motif NANOG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_118450875 15.558 NM_010024
Dct
dopachrome tautomerase
chr4_+_80480116 13.078 NM_031202
Tyrp1
tyrosinase-related protein 1
chr14_-_49282546 11.901 NM_144841
Otx2
orthodenticle homolog 2 (Drosophila)
chr14_-_37911383 10.214 NM_130878
Cdhr1
cadherin-related family member 1
chr3_+_17695743 8.589 6430547I21Rik
RIKEN cDNA 6430547I21 gene
chr3_+_107895985 8.162 NM_008141
Gnat2
guanine nucleotide binding protein, alpha transducing 2
chr9_-_96978102 6.951 Slc25a36
solute carrier family 25, member 36
chr12_-_11215753 6.816 NM_019544
Msgn1
mesogenin 1
chr3_-_86352170 6.771 NM_011839
Mab21l2
mab-21-like 2 (C. elegans)
chr19_+_54003803 6.757 Pdcd4
programmed cell death 4
chr2_+_119000244 6.682 NM_001039223
Gm14137
predicted gene 14137
chr19_-_12840121 6.652 NM_170786
Cntf
ciliary neurotrophic factor
chr10_+_73284612 6.585 NM_001142735
NM_001142736
NM_001142737
NM_001142738
NM_001142739
NM_001142740
NM_001142741
NM_001142742
NM_001142743
NM_001142746
NM_001142747
NM_001142748
NM_001142760
NM_023115
Pcdh15













protocadherin 15













chr3_+_121747377 6.566 NM_007378
Abca4
ATP-binding cassette, sub-family A (ABC1), member 4
chr1_+_6720153 6.284 St18
suppression of tumorigenicity 18
chr14_+_79915429 6.232 Elf1
E74-like factor 1
chr4_-_109959366 6.179 NM_001163399
NM_010488
Elavl4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr1_-_4350323 6.031 NM_011283
Rp1
retinitis pigmentosa 1 (human)
chr2_-_62321694 5.899 NM_008100
Gcg
glucagon
chr11_-_99184254 5.689 NM_133730
Krt25
keratin 25
chr17_-_51878720 5.660 Satb1
special AT-rich sequence binding protein 1
chr2_+_129838084 5.551 NM_009374
Tgm3
transglutaminase 3, E polypeptide
chr3_+_101814059 5.465 NM_178777
Nhlh2
nescient helix loop helix 2
chr9_+_64658817 5.323 NM_001162917
Dennd4a
DENN/MADD domain containing 4A
chr6_-_72382855 5.252


chr9_+_46721685 5.109 2900052N01Rik
RIKEN cDNA 2900052N01 gene
chr13_-_64599099 4.864 NM_001195435
1190003K10Rik
RIKEN cDNA 1190003K10 gene
chr18_-_81183260 4.852 NM_178280
Sall3
sal-like 3 (Drosophila)
chr4_-_109959185 4.782 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr11_+_87032504 4.745 Trim37
tripartite motif-containing 37
chr11_-_99212407 4.661 NM_010666
Krt27
keratin 27
chr7_-_150085870 4.488 NM_009377
Th
tyrosine hydroxylase
chr1_-_65097587 4.479 NM_007777
Cryge
crystallin, gamma E
chr6_-_136730254 4.357 NM_001127318
NM_145067
Gucy2c

guanylate cyclase 2c

chr7_+_97535516 4.334 Sytl2
synaptotagmin-like 2
chr2_+_69058005 4.274 NM_021331
G6pc2
glucose-6-phosphatase, catalytic, 2
chr2_+_153988342 4.235 NM_025990
2310021H06Rik
RIKEN cDNA 2310021H06 gene
chr6_+_128995918 4.207 NM_153094
Klrb1f
killer cell lectin-like receptor subfamily B member 1F
chr6_-_116666759 4.082 NM_178768
Tmem72
transmembrane protein 72
chr7_-_16465217 4.081 NM_007770
Crx
cone-rod homeobox containing gene
chr10_+_39332739 4.059 NM_134000
Traf3ip2
TRAF3 interacting protein 2
chr10_+_39332934 3.967 Traf3ip2
TRAF3 interacting protein 2
chr10_+_126437764 3.916 NM_009635
Avil
advillin
chr4_-_109078858 3.893


chr5_-_101001191 3.783 Plac8
placenta-specific 8
chrX_+_104871850 3.748 NM_145224
Tbx22
T-box 22
chr7_+_97535490 3.741 NM_001040087
NM_001040088
Sytl2

synaptotagmin-like 2

chr5_+_138628733 3.738 NM_178612
Cnpy4
canopy 4 homolog (zebrafish)
chr2_-_58012447 3.563 NM_139200
Cytip
cytohesin 1 interacting protein
chr9_-_85637765 3.555 NM_001081282
Ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr16_-_57754816 3.550 NM_007739
Col8a1
collagen, type VIII, alpha 1
chr15_+_101303908 3.536 NM_010667
Krt86
keratin 86
chr9_+_91263809 3.528 NM_009576
Zic4
zinc finger protein of the cerebellum 4
chr19_+_7344253 3.505 NM_054048
Rcor2
REST corepressor 2
chr1_+_19198994 3.420 NM_009334
Tcfap2b
transcription factor AP-2 beta
chr9_-_109986879 3.411 Dhx30
DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr14_+_27813547 3.396 NM_010420
Hesx1
homeobox gene expressed in ES cells
chr1_+_169298077 3.394 Aldh9a1
aldehyde dehydrogenase 9, subfamily A1
chr7_-_26506741 3.170


chr12_+_72456427 3.128


chr7_-_86531587 3.093 Rlbp1
retinaldehyde binding protein 1
chr4_+_15211137 2.944 Tmem64
transmembrane protein 64
chr6_+_143156520 2.897 Etnk1
ethanolamine kinase 1
chr7_+_29666674 2.885 NM_001110807
Capn12
calpain 12
chr7_+_119253816 2.827 Usp47
ubiquitin specific peptidase 47
chr5_-_101001209 2.824 NM_139198
Plac8
placenta-specific 8
chr5_+_23919268 2.778 NM_183000
Accn3
amiloride-sensitive cation channel 3
chr9_+_92502076 2.776


chrX_-_153853209 2.771 NM_011077
Phex
phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)
chr2_+_129949020 2.748 NM_177726
Tgm6
transglutaminase 6
chr4_+_109650629 2.731 NM_172296
Dmrta2
doublesex and mab-3 related transcription factor like family A2
chr11_+_94871620 2.731 Samd14
sterile alpha motif domain containing 14
chr4_-_109960078 2.707 NM_001038698
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr5_-_54098762 2.692 NM_009827
Cckar
cholecystokinin A receptor
chr14_+_124059330 2.685 NM_145467
Itgbl1
integrin, beta-like 1
chr12_-_88579550 2.670 NM_027744
4933437F05Rik
RIKEN cDNA 4933437F05 gene
chr3_+_89586320 2.668 Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chr17_+_80706746 2.648 NM_001145452
Arhgef33
Rho guanine nucleotide exchange factor (GEF) 33
chr15_-_102196701 2.615 NM_130458
Sp7
Sp7 transcription factor 7
chr8_-_3625251 2.501 NM_008790
Pcp2
Purkinje cell protein 2 (L7)
chr11_+_95885858 2.479 NM_008119
Gip
gastric inhibitory polypeptide
chr1_-_180259089 2.473 Hnrnpu
heterogeneous nuclear ribonucleoprotein U
chr6_+_30491641 2.461 NM_001024698
Cpa2
carboxypeptidase A2, pancreatic
chr10_-_116333934 2.460 NM_001033333
Gm239
predicted gene 239
chr1_+_6720087 2.421 NM_173868
St18
suppression of tumorigenicity 18
chr1_-_89291303 2.396 NM_001110227
Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr1_-_167865030 2.373 NM_198933
NM_198934
Pou2f1

POU domain, class 2, transcription factor 1

chr6_+_115881925 2.354 NM_145383
Rho
rhodopsin
chr16_+_88829238 2.336 NM_013713
Krtap15
keratin associated protein 15
chr5_-_123438517 2.320 NM_001005866
Kdm2b
lysine (K)-specific demethylase 2B
chr3_-_63654912 2.319 NM_001177732
NM_001177733
NM_183191
Plch1


phospholipase C, eta 1


chr12_+_87702066 2.257 NM_001159500
Esrrb
estrogen related receptor, beta
chr7_-_149865451 2.226 NM_001185083
NM_001185084
NM_008387
Ins2


insulin II


chrX_-_35087783 2.209 NM_001100465
Rhox2h
reproductive homeobox 2H
chr11_-_33103458 2.197 NM_019916
Tlx3
T-cell leukemia, homeobox 3
chr1_+_106665395 2.179 NM_011800
Cdh20
cadherin 20
chr11_+_11014018 2.170 NM_177033
Vwc2
von Willebrand factor C domain containing 2
chr1_-_79436564 2.132 NM_009129
Scg2
secretogranin II
chr19_-_29409041 2.132 NM_011272
Rln1
relaxin 1
chrX_+_34944974 2.127 NM_001085348
Rhox2e
reproductive homeobox 2E
chr11_-_94154354 2.127 Luc7l3
LUC7-like 3 (S. cerevisiae)
chr11_-_99427891 2.120 NM_023511
Krtap3-1
keratin associated protein 3-1
chr12_+_39510297 2.095 NM_001163154
Etv1
ets variant gene 1
chr7_-_91763744 2.054 Zfand6
zinc finger, AN1-type domain 6
chr3_-_154718282 2.035 NM_177066
Tnni3k
TNNI3 interacting kinase
chr15_-_101723333 2.025 NM_001033177
Krt76
keratin 76
chr10_-_20880559 2.019 NM_001198914
NM_010848
Myb

myeloblastosis oncogene

chr11_-_102807774 2.007 NM_011795
C1ql1
complement component 1, q subcomponent-like 1
chr9_+_69855789 1.996 Bnip2
BCL2/adenovirus E1B interacting protein 2
chr12_-_105711324 1.989 NM_010351
Gsc
goosecoid homeobox
chr18_+_44264117 1.951 NM_030061
Spink12
serine peptidase inhibitor, Kazal type 11
chr10_+_41250456 1.931 Cd164
CD164 antigen
chr11_+_101848369 1.926 NM_029287
1700006E09Rik
RIKEN cDNA 1700006E09 gene
chrX_+_34784986 1.923 NM_001085348
NM_029203
Rhox2e
Rhox2a
reproductive homeobox 2E
reproductive homeobox 2A
chr17_+_47047407 1.922 NM_008938
Prph2
peripherin 2
chr16_+_37580238 1.893 NM_013547
Hgd
homogentisate 1, 2-dioxygenase
chr17_+_49754460 1.877 NM_177052
Kif6
kinesin family member 6
chr6_+_134874663 1.874 Cdkn1b
cyclin-dependent kinase inhibitor 1B
chr8_+_13037791 1.853 F10
coagulation factor X
chr6_-_98877291 1.853


chrX_-_35057976 1.845 NM_001114153
Rhox2g
reproductive homeobox 2G
chr15_-_66644199 1.841 Sla
src-like adaptor
chr1_-_65149923 1.791 NM_007774
Cryga
crystallin, gamma A
chr11_-_99199267 1.776 NM_001033397
Krt26
keratin 26
chr15_+_39491073 1.769 Rims2
regulating synaptic membrane exocytosis 2
chr18_+_57628139 1.765 NM_001134697
Ctxn3
cortexin 3
chr15_+_80453912 1.741 NM_010815
Grap2
GRB2-related adaptor protein 2
chr4_+_64785795 1.720 Pappa
pregnancy-associated plasma protein A
chr17_-_72102224 1.719 NM_146082
BC027072
cDNA sequence BC027072
chr12_+_53800302 1.718 Akap6
A kinase (PRKA) anchor protein 6
chr18_+_37467108 1.715 NM_053129
Pcdhb4
protocadherin beta 4
chr2_+_163372889 1.705 NM_008261
Hnf4a
hepatic nuclear factor 4, alpha
chr7_+_130267661 1.682 Tnrc6a
trinucleotide repeat containing 6a
chr11_-_33893151 1.668 NM_001190886
Kcnip1
Kv channel-interacting protein 1
chr5_+_140019846 1.659 NM_013702
Uncx
UNC homeobox
chr2_-_165709697 1.655 Zmynd8
zinc finger, MYND-type containing 8
chr15_-_101404334 1.649 NM_133357
Krt75
keratin 75
chr5_+_27588462 1.642 NM_001136060
Dpp6
dipeptidylpeptidase 6
chr10_-_106922986 1.639 NM_008656
Myf5
myogenic factor 5
chr6_+_54251485 1.635


chr15_+_8918001 1.634 NM_198024
Ranbp3l
RAN binding protein 3-like
chr19_-_39723518 1.613 NM_001024719
Cyp2c67
cytochrome P450, family 2, subfamily c, polypeptide 67
chr4_-_126540249 1.610 Zmym4
zinc finger, MYM-type 4
chr7_+_104840013 1.601 Rsf1
remodeling and spacing factor 1
chr2_-_127346987 1.599 Kcnip3
Kv channel interacting protein 3, calsenilin
chr10_+_128143313 1.580 NM_021882
Pmel
premelanosome protein
chr1_-_175157322 1.573 NM_010184
Fcer1a
Fc receptor, IgE, high affinity I, alpha polypeptide
chr1_-_173165051 1.572


chr4_+_133109291 1.566 NM_011850
Nr0b2
nuclear receptor subfamily 0, group B, member 2
chr7_+_86418127 1.561 NM_018811
Abhd2
abhydrolase domain containing 2
chr11_+_94871643 1.560 Samd14
sterile alpha motif domain containing 14
chr9_+_75623899 1.549 Bmp5
bone morphogenetic protein 5
chr1_+_109258889 1.529 NM_025867
Serpinb11
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr4_-_129167980 1.518 NM_080442
Tssk3
testis-specific serine kinase 3
chr2_-_27118325 1.511 Vav2
vav 2 oncogene
chr4_+_150302107 1.507 NM_001077509
Tnfrsf9
tumor necrosis factor receptor superfamily, member 9
chr5_+_19413335 1.496 NM_001170745
NM_015823
Magi2

membrane associated guanylate kinase, WW and PDZ domain containing 2

chr19_-_8040489 1.493 NM_134256
AB056442
cDNA sequence AB056442
chr5_-_138628389 1.476 NM_009315
Taf6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_-_167124096 1.465


chr7_-_19895354 1.464 NM_008036
Fosb
FBJ osteosarcoma oncogene B
chr1_+_174486066 1.459 NM_177723
Vsig8
V-set and immunoglobulin domain containing 8
chr8_-_3625510 1.458 NM_001129803
Pcp2
Purkinje cell protein 2 (L7)
chr15_+_58731646 1.452 Rnf139
ring finger protein 139
chr17_-_27304602 1.439 NM_173027
Ip6k3
inositol hexaphosphate kinase 3
chr5_-_52541869 1.430 Dhx15
DEAH (Asp-Glu-Ala-His) box polypeptide 15
chr9_+_118387306 1.425 NM_001164789
NM_010136
Eomes

eomesodermin homolog (Xenopus laevis)

chr2_-_127347102 1.423 NM_019789
Kcnip3
Kv channel interacting protein 3, calsenilin
chr7_+_36234110 1.422 NM_001199015
NM_001199016
NM_021291
Slc7a9


solute carrier family 7 (cationic amino acid transporter, y+ system), member 9


chr6_+_13821522 1.420 1110019D14Rik
RIKEN cDNA 1110019D14 gene
chr8_+_4238862 1.409 Map2k7
mitogen-activated protein kinase kinase 7
chr11_-_99471502 1.391 NM_001099346
Gm11937
predicted gene 11937
chr1_-_180259336 1.373 Hnrnpu
heterogeneous nuclear ribonucleoprotein U
chr7_-_52965801 1.372 Sphk2
sphingosine kinase 2
chr16_+_37580303 1.371 Hgd
homogentisate 1, 2-dioxygenase
chr8_+_97197870 1.367 Arl2bp
ADP-ribosylation factor-like 2 binding protein
chr19_+_31943250 1.362 NM_001081074
A1cf
APOBEC1 complementation factor
chr12_+_53800369 1.360 NM_198111
Akap6
A kinase (PRKA) anchor protein 6
chr5_+_37442095 1.346 NM_178394
Jakmip1
janus kinase and microtubule interacting protein 1
chr4_-_136891931 1.344 Cdc42
cell division cycle 42 homolog (S. cerevisiae)
chr10_+_58866370 1.343 NM_023530
Pla2g12b
phospholipase A2, group XIIB
chr5_+_29972960 1.334 Ube3c
ubiquitin protein ligase E3C
chr9_+_32201569 1.332 NM_001168354
Kcnj1
potassium inwardly-rectifying channel, subfamily J, member 1
chr2_-_79296732 1.329 NM_010894
Neurod1
neurogenic differentiation 1
chr1_-_89283173 1.322


chr2_+_9802878 1.319 4930412O13Rik
RIKEN cDNA 4930412O13 gene
chr7_-_94641859 1.313 NM_011661
Tyr
tyrosinase
chr7_+_86418082 1.301 Abhd2
abhydrolase domain containing 2
chr17_+_35670145 1.299 NM_020576
Psors1c2
psoriasis susceptibility 1 candidate 2 (human)
chr3_+_89324085 1.298 NM_080466
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr3_-_20142068 1.298 NM_007753
Cpa3
carboxypeptidase A3, mast cell
chr5_+_27588579 1.292 Dpp6
dipeptidylpeptidase 6
chr16_+_20692792 1.279


chr7_+_130267398 1.267 NM_144925
Tnrc6a
trinucleotide repeat containing 6a
chr13_+_8202111 1.263 NM_052977
Adarb2
adenosine deaminase, RNA-specific, B2
chr6_+_57159851 1.256 NM_053235
Vmn1r13
vomeronasal 1 receptor 13
chr9_+_106366204 1.255


chr17_+_74898763 1.247 Yipf4
Yip1 domain family, member 4
chr10_-_116786025 1.234 Cpsf6
cleavage and polyadenylation specific factor 6
chr1_-_129998984 1.223 NM_027678
Zranb3
zinc finger, RAN-binding domain containing 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.22 1.73e-13 GO:0048513 organ development
1.91 6.42e-13 GO:0048856 anatomical structure development
1.81 7.07e-13 GO:0032502 developmental process
1.91 3.31e-11 GO:0048731 system development
1.75 1.28e-09 GO:0007275 multicellular organismal development
2.09 9.09e-08 GO:0009653 anatomical structure morphogenesis
1.59 5.96e-07 GO:0060255 regulation of macromolecule metabolic process
1.81 1.68e-06 GO:0030154 cell differentiation
1.69 1.73e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.73 1.82e-06 GO:0006355 regulation of transcription, DNA-dependent
3.23 2.08e-06 GO:0007423 sensory organ development
1.68 2.27e-06 GO:0010556 regulation of macromolecule biosynthetic process
2.18 2.32e-06 GO:0050793 regulation of developmental process
1.71 3.10e-06 GO:0051252 regulation of RNA metabolic process
1.77 4.37e-06 GO:0048869 cellular developmental process
1.53 7.39e-06 GO:0031323 regulation of cellular metabolic process
2.52 8.10e-06 GO:0009887 organ morphogenesis
1.64 8.97e-06 GO:0010468 regulation of gene expression
1.66 1.20e-05 GO:0048522 positive regulation of cellular process
1.52 1.37e-05 GO:0080090 regulation of primary metabolic process
1.97 1.58e-05 GO:0010604 positive regulation of macromolecule metabolic process
2.28 2.72e-05 GO:0045595 regulation of cell differentiation
1.78 4.59e-05 GO:0006351 transcription, DNA-dependent
1.78 5.01e-05 GO:0032774 RNA biosynthetic process
1.59 5.20e-05 GO:0048518 positive regulation of biological process
4.02 5.68e-05 GO:0045165 cell fate commitment
2.72 7.57e-05 GO:0007417 central nervous system development
2.13 8.85e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
2.15 8.96e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.86 1.12e-04 GO:0009893 positive regulation of metabolic process
1.57 1.29e-04 GO:0031326 regulation of cellular biosynthetic process
2.84 1.50e-04 GO:0007389 pattern specification process
1.56 1.51e-04 GO:0009889 regulation of biosynthetic process
1.57 1.56e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.57 1.61e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.94 1.69e-04 GO:0007399 nervous system development
1.38 1.78e-04 GO:0032501 multicellular organismal process
1.44 2.44e-04 GO:0019222 regulation of metabolic process
2.04 2.52e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.09 2.81e-04 GO:0009888 tissue development
2.17 3.39e-04 GO:0051254 positive regulation of RNA metabolic process
2.08 3.42e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.26 4.54e-04 GO:0050794 regulation of cellular process
2.07 4.97e-04 GO:2000026 regulation of multicellular organismal development
2.16 5.17e-04 GO:0045893 positive regulation of transcription, DNA-dependent
2.10 5.41e-04 GO:0010628 positive regulation of gene expression
3.02 6.61e-04 GO:0048568 embryonic organ development
1.83 6.89e-04 GO:0031325 positive regulation of cellular metabolic process
1.59 7.22e-04 GO:0048519 negative regulation of biological process
3.34 8.41e-04 GO:0001654 eye development
1.75 1.75e-03 GO:0051239 regulation of multicellular organismal process
2.74 1.84e-03 GO:0007420 brain development
2.17 1.84e-03 GO:0010629 negative regulation of gene expression
2.05 1.96e-03 GO:0022008 neurogenesis
2.28 2.17e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.24 2.17e-03 GO:0050789 regulation of biological process
1.59 2.66e-03 GO:0048523 negative regulation of cellular process
1.93 2.90e-03 GO:0009891 positive regulation of biosynthetic process
3.41 3.36e-03 GO:0043010 camera-type eye development
1.94 3.38e-03 GO:0031328 positive regulation of cellular biosynthetic process
2.06 3.62e-03 GO:0048699 generation of neurons
2.46 3.68e-03 GO:0048598 embryonic morphogenesis
2.50 3.77e-03 GO:0007267 cell-cell signaling
2.20 4.27e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.99 4.72e-03 GO:0048468 cell development
2.17 5.51e-03 GO:0007155 cell adhesion
8.32 6.14e-03 GO:0045168 cell-cell signaling involved in cell fate commitment
2.16 6.24e-03 GO:0051253 negative regulation of RNA metabolic process
2.15 6.78e-03 GO:0022610 biological adhesion
1.22 6.80e-03 GO:0065007 biological regulation
2.08 7.07e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
7.56 1.34e-02 GO:0008543 fibroblast growth factor receptor signaling pathway
2.51 1.53e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.78 1.90e-02 GO:0003002 regionalization
2.00 1.95e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
3.14 2.05e-02 GO:0048562 embryonic organ morphogenesis
2.01 2.69e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.18 2.71e-02 GO:0048646 anatomical structure formation involved in morphogenesis
4.10 3.01e-02 GO:0042471 ear morphogenesis
2.16 3.48e-02 GO:0051094 positive regulation of developmental process
1.81 3.51e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.98 3.86e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
3.55 4.05e-02 GO:0043583 ear development
2.89 4.10e-02 GO:0030900 forebrain development
1.94 4.35e-02 GO:0031327 negative regulation of cellular biosynthetic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
4.39 1.48e-05 GO:0005882 intermediate filament
3.97 1.80e-05 GO:0045111 intermediate filament cytoskeleton
1.62 8.74e-04 GO:0005576 extracellular region
9.85 4.72e-03 GO:0042470 melanosome
9.85 4.72e-03 GO:0048770 pigment granule
6.83 1.32e-02 GO:0045095 keratin filament

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.35 4.07e-08 GO:0030528 transcription regulator activity
2.47 8.12e-08 GO:0001071 nucleic acid binding transcription factor activity
2.47 8.12e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
1.22 1.25e-06 GO:0005488 binding
1.81 2.37e-06 GO:0003677 DNA binding
1.54 2.09e-04 GO:0003676 nucleic acid binding
2.22 2.11e-04 GO:0043565 sequence-specific DNA binding
1.31 4.54e-04 GO:0005515 protein binding
2.69 1.28e-03 GO:0016564 transcription repressor activity
1.75 1.69e-02 GO:0005102 receptor binding
2.36 2.58e-02 GO:0016563 transcription activator activity