Motif ID: NANOG.p2

Z-value: 0.953


Transcription factors associated with NANOG.p2:

Gene SymbolEntrez IDGene Name
Nanog 71950 Nanog homeobox

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nanogchr6_+_1226575060.223.5e-03Click!


Activity profile for motif NANOG.p2.

activity profile for motif NANOG.p2


Sorted Z-values histogram for motif NANOG.p2

Sorted Z-values for motif NANOG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_118450875 15.558 NM_010024
 Dct
dopachrome tautomerase
chr4_+_80480116 13.078 NM_031202
 Tyrp1
tyrosinase-related protein 1
chr14_-_49282546 11.901 NM_144841
 Otx2
orthodenticle homolog 2 (Drosophila)
chr14_-_37911383 10.214 NM_130878
 Cdhr1
cadherin-related family member 1
chr3_+_17695743 8.589 6430547I21Rik
RIKEN cDNA 6430547I21 gene
chr3_+_107895985 8.162 NM_008141
 Gnat2
guanine nucleotide binding protein, alpha transducing 2
chr9_-_96978102 6.951 Slc25a36
solute carrier family 25, member 36
chr12_-_11215753 6.816 NM_019544
 Msgn1
mesogenin 1
chr3_-_86352170 6.771 NM_011839
 Mab21l2
mab-21-like 2 (C. elegans)
chr19_+_54003803 6.757 Pdcd4
programmed cell death 4
chr2_+_119000244 6.682 NM_001039223
 Gm14137
predicted gene 14137
chr19_-_12840121 6.652 NM_170786
 Cntf
ciliary neurotrophic factor
chr10_+_73284612 6.585 NM_001142735
NM_001142736
NM_001142737
NM_001142738
NM_001142739
NM_001142740
NM_001142741
NM_001142742
NM_001142743
NM_001142746
NM_001142747
NM_001142748
NM_001142760
NM_023115
 Pcdh15













protocadherin 15













chr3_+_121747377 6.566 NM_007378
 Abca4
ATP-binding cassette, sub-family A (ABC1), member 4
chr1_+_6720153 6.284 St18
suppression of tumorigenicity 18
chr14_+_79915429 6.232 Elf1
E74-like factor 1
chr4_-_109959366 6.179 NM_001163399
NM_010488
 Elavl4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr1_-_4350323 6.031 NM_011283
 Rp1
retinitis pigmentosa 1 (human)
chr2_-_62321694 5.899 NM_008100
 Gcg
glucagon
chr11_-_99184254 5.689 NM_133730
 Krt25
keratin 25

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 85 entries
Enrichment   P-value GO Accession GO Term
8.32 6.14e-03 GO:0045168 cell-cell signaling involved in cell fate commitment
7.56 1.34e-02 GO:0008543 fibroblast growth factor receptor signaling pathway
4.10 3.01e-02 GO:0042471 ear morphogenesis
4.02 5.68e-05 GO:0045165 cell fate commitment
3.55 4.05e-02 GO:0043583 ear development
3.41 3.36e-03 GO:0043010 camera-type eye development
3.34 8.41e-04 GO:0001654 eye development
3.23 2.08e-06 GO:0007423 sensory organ development
3.14 2.05e-02 GO:0048562 embryonic organ morphogenesis
3.02 6.61e-04 GO:0048568 embryonic organ development
2.89 4.10e-02 GO:0030900 forebrain development
2.84 1.50e-04 GO:0007389 pattern specification process
2.78 1.90e-02 GO:0003002 regionalization
2.74 1.84e-03 GO:0007420 brain development
2.72 7.57e-05 GO:0007417 central nervous system development
2.52 8.10e-06 GO:0009887 organ morphogenesis
2.51 1.53e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.50 3.77e-03 GO:0007267 cell-cell signaling
2.46 3.68e-03 GO:0048598 embryonic morphogenesis
2.28 2.72e-05 GO:0045595 regulation of cell differentiation

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
9.85 4.72e-03 GO:0042470 melanosome
9.85 4.72e-03 GO:0048770 pigment granule
6.83 1.32e-02 GO:0045095 keratin filament
4.39 1.48e-05 GO:0005882 intermediate filament
3.97 1.80e-05 GO:0045111 intermediate filament cytoskeleton
1.62 8.74e-04 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
Enrichment   P-value GO Accession GO Term
2.69 1.28e-03 GO:0016564 transcription repressor activity
2.47 8.12e-08 GO:0001071 nucleic acid binding transcription factor activity
2.47 8.12e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
2.36 2.58e-02 GO:0016563 transcription activator activity
2.35 4.07e-08 GO:0030528 transcription regulator activity
2.22 2.11e-04 GO:0043565 sequence-specific DNA binding
1.81 2.37e-06 GO:0003677 DNA binding
1.75 1.69e-02 GO:0005102 receptor binding
1.54 2.09e-04 GO:0003676 nucleic acid binding
1.31 4.54e-04 GO:0005515 protein binding
1.22 1.25e-06 GO:0005488 binding