Motif ID: NFE2.p2

Z-value: 1.302


Transcription factors associated with NFE2.p2:

Gene SymbolEntrez IDGene Name
Nfe2 18022 nuclear factor, erythroid derived 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfe2chr15_-_1030857030.064.2e-01Click!


Activity profile for motif NFE2.p2.

activity profile for motif NFE2.p2


Sorted Z-values histogram for motif NFE2.p2

Sorted Z-values for motif NFE2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_44090222 18.253 Rcan2
regulator of calcineurin 2
chr19_-_36811137 17.957 Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr17_+_44090139 17.827 NM_030598
 Rcan2
regulator of calcineurin 2
chr19_-_36811090 17.386 NM_016854
 Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr17_-_90436488 15.975 Nrxn1
neurexin I
chr14_-_68743060 15.771 NM_008691
 Nefm
neurofilament, medium polypeptide
chr14_-_68742863 15.678 Nefm
neurofilament, medium polypeptide
chr7_+_138087002 15.351 Htra1
HtrA serine peptidase 1
chr17_+_44090341 15.120 Rcan2
regulator of calcineurin 2
chr18_-_60769648 14.989 NM_001109975
 Synpo
synaptopodin
chr17_+_44090192 13.303 Rcan2
regulator of calcineurin 2
chr6_+_129483295 13.089 Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr1_+_58086804 12.690 NM_009676
 Aox1
aldehyde oxidase 1
chr6_+_129483238 12.667 Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr11_-_30549383 12.577 NM_029344
 Acyp2
acylphosphatase 2, muscle type
chr7_-_133942767 12.500 NM_007438
 Aldoa
aldolase A, fructose-bisphosphate
chr6_+_129483154 12.446 Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr7_+_147020072 12.384 NM_177469
 Gpr123
G protein-coupled receptor 123
chr14_-_52530382 12.178 Ndrg2
N-myc downstream regulated gene 2
chr2_-_80421054 12.090 NM_016965
 Nckap1
NCK-associated protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 29 entries
Enrichment   P-value GO Accession GO Term
15.40 1.10e-02 GO:0047496 vesicle transport along microtubule
9.24 4.31e-04 GO:0010970 microtubule-based transport
9.24 4.31e-04 GO:0030705 cytoskeleton-dependent intracellular transport
5.01 7.09e-03 GO:0008360 regulation of cell shape
4.84 2.57e-02 GO:0050808 synapse organization
3.02 2.08e-02 GO:0060537 muscle tissue development
2.39 4.99e-03 GO:0006163 purine nucleotide metabolic process
2.39 3.97e-02 GO:0009150 purine ribonucleotide metabolic process
2.35 2.83e-03 GO:0072521 purine-containing compound metabolic process
2.34 3.17e-04 GO:0006753 nucleoside phosphate metabolic process
2.34 3.17e-04 GO:0009117 nucleotide metabolic process
2.34 2.38e-03 GO:0043086 negative regulation of catalytic activity
2.32 2.53e-02 GO:0031401 positive regulation of protein modification process
2.16 2.92e-03 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
2.16 3.08e-03 GO:0044092 negative regulation of molecular function
2.00 8.15e-04 GO:0031399 regulation of protein modification process
2.00 8.29e-03 GO:0046483 heterocycle metabolic process
1.96 2.22e-02 GO:0046907 intracellular transport
1.92 7.74e-04 GO:0042592 homeostatic process
1.84 8.48e-03 GO:0051649 establishment of localization in cell

Gene overrepresentation in compartment category:

Showing 1 to 20 of 29 entries
Enrichment   P-value GO Accession GO Term
6.68 3.30e-07 GO:0000502 proteasome complex
3.56 4.18e-02 GO:0042383 sarcolemma
3.12 7.68e-04 GO:0031252 cell leading edge
2.98 1.74e-06 GO:0048471 perinuclear region of cytoplasm
2.44 3.23e-07 GO:0043005 neuron projection
2.43 1.64e-03 GO:0042598 vesicular fraction
2.42 5.10e-03 GO:0030425 dendrite
2.37 2.73e-03 GO:0043025 neuronal cell body
2.37 2.04e-02 GO:0030424 axon
2.34 7.13e-03 GO:0005792 microsome
2.33 2.77e-03 GO:0044297 cell body
2.32 2.33e-03 GO:0005625 soluble fraction
2.17 7.48e-04 GO:0045202 synapse
2.15 3.29e-02 GO:0044456 synapse part
2.10 8.52e-10 GO:0000267 cell fraction
2.09 1.06e-08 GO:0042995 cell projection
2.02 2.94e-06 GO:0005626 insoluble fraction
1.97 2.57e-05 GO:0005624 membrane fraction
1.68 1.16e-04 GO:0005829 cytosol
1.63 7.62e-04 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
8.21 5.85e-03 GO:0005212 structural constituent of eye lens
2.33 2.28e-05 GO:0008092 cytoskeletal protein binding
2.30 1.83e-02 GO:0003779 actin binding
1.83 1.97e-03 GO:0019899 enzyme binding
1.42 2.35e-10 GO:0005515 protein binding
1.41 2.45e-02 GO:0016787 hydrolase activity
1.33 2.13e-05 GO:0003824 catalytic activity
1.21 1.06e-07 GO:0005488 binding