Motif ID: NFE2L1.p2

Z-value: 2.057


Transcription factors associated with NFE2L1.p2:

Gene SymbolEntrez IDGene Name
Nfe2l1 18023 nuclear factor, erythroid derived 2,-like 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfe2l1chr11_-_966907840.645.9e-22Click!


Activity profile for motif NFE2L1.p2.

activity profile for motif NFE2L1.p2


Sorted Z-values histogram for motif NFE2L1.p2

Sorted Z-values for motif NFE2L1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_126646303 37.267 NM_001034168
 Ank2
ankyrin 2, brain
chr9_-_66880619 31.593 Tpm1
tropomyosin 1, alpha
chr8_-_126417352 29.156 Acta1
actin, alpha 1, skeletal muscle
chr19_+_5492584 26.411


chr11_+_78137699 22.056 NM_009657
 Aldoc
aldolase C, fructose-bisphosphate
chr3_+_67868723 19.791 NM_001113420
NM_001113421
 Schip1

schwannomin interacting protein 1

chr5_+_136363769 19.770 NM_013560
 Hspb1
heat shock protein 1
chr4_-_126427788 19.111 Ncdn
neurochondrin
chr5_+_136363810 18.653 Hspb1
heat shock protein 1
chr4_+_103236110 18.261


chr1_-_71686889 18.241 Fn1
fibronectin 1
chr18_+_36526187 18.139 0610010O12Rik
RIKEN cDNA 0610010O12 gene
chr6_-_125112509 17.492 Gapdh
Gm5523
Gm10481
glyceraldehyde-3-phosphate dehydrogenase
glyceraldehyde-3-phosphate dehydrogenase pseudogene
glyceraldehyde-3-phosphate dehydrogenase pseudogene
chr4_+_138012860 17.251 Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr5_+_136363914 16.920 Hspb1
heat shock protein 1
chr5_+_104868321 16.858 Spp1
secreted phosphoprotein 1
chrX_-_22797942 16.741 Klhl13
kelch-like 13 (Drosophila)
chr19_-_10175969 16.517 Fads2
fatty acid desaturase 2
chr1_-_166368439 16.415 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr12_-_102988596 16.194



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 185 entries
Enrichment   P-value GO Accession GO Term
5.05 3.93e-02 GO:0072384 organelle transport along microtubule
3.85 2.18e-03 GO:0006096 glycolysis
3.49 5.29e-03 GO:0043242 negative regulation of protein complex disassembly
3.40 1.45e-04 GO:0006754 ATP biosynthetic process
3.37 1.88e-02 GO:0006084 acetyl-CoA metabolic process
3.33 3.06e-03 GO:0006007 glucose catabolic process
3.22 7.35e-05 GO:0009145 purine nucleoside triphosphate biosynthetic process
3.16 1.48e-02 GO:0031333 negative regulation of protein complex assembly
3.14 2.41e-04 GO:0009206 purine ribonucleoside triphosphate biosynthetic process
3.14 9.02e-03 GO:0019320 hexose catabolic process
3.13 1.48e-04 GO:0009142 nucleoside triphosphate biosynthetic process
3.10 3.38e-04 GO:0009201 ribonucleoside triphosphate biosynthetic process
3.03 2.88e-02 GO:0043244 regulation of protein complex disassembly
3.02 1.75e-02 GO:0046365 monosaccharide catabolic process
2.81 6.57e-04 GO:0009152 purine ribonucleotide biosynthetic process
2.77 1.05e-02 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
2.77 1.73e-02 GO:0046164 alcohol catabolic process
2.77 1.73e-02 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.77 1.73e-02 GO:0051494 negative regulation of cytoskeleton organization
2.73 1.38e-02 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

Gene overrepresentation in compartment category:

Showing 1 to 20 of 95 entries
Enrichment   P-value GO Accession GO Term
6.32 3.38e-02 GO:0019773 proteasome core complex, alpha-subunit complex
4.43 9.79e-03 GO:0005839 proteasome core complex
3.71 3.14e-07 GO:0000502 proteasome complex
3.61 2.13e-03 GO:0030666 endocytic vesicle membrane
3.41 4.88e-03 GO:0016469 proton-transporting two-sector ATPase complex
3.39 2.23e-09 GO:0030017 sarcomere
3.28 1.89e-04 GO:0030018 Z disc
3.24 1.92e-05 GO:0031674 I band
3.21 2.39e-09 GO:0044449 contractile fiber part
3.19 4.09e-11 GO:0043292 contractile fiber
3.18 5.65e-10 GO:0030016 myofibril
2.99 1.74e-02 GO:0005905 coated pit
2.96 3.87e-03 GO:0030665 clathrin coated vesicle membrane
2.89 4.33e-04 GO:0030662 coated vesicle membrane
2.76 1.25e-02 GO:0005901 caveola
2.72 9.93e-03 GO:0030117 membrane coat
2.72 9.93e-03 GO:0048475 coated membrane
2.61 7.95e-03 GO:0030139 endocytic vesicle
2.60 1.46e-06 GO:0019717 synaptosome
2.57 1.20e-14 GO:0030425 dendrite

Gene overrepresentation in function category:

Showing 1 to 20 of 41 entries
Enrichment   P-value GO Accession GO Term
6.12 4.16e-03 GO:0046933 hydrogen ion transporting ATP synthase activity, rotational mechanism
2.72 1.67e-02 GO:0042625 ATPase activity, coupled to transmembrane movement of ions
2.19 1.11e-02 GO:0005516 calmodulin binding
2.14 9.99e-10 GO:0032403 protein complex binding
2.06 1.42e-02 GO:0015077 monovalent inorganic cation transmembrane transporter activity
2.05 1.12e-06 GO:0003779 actin binding
1.96 2.46e-10 GO:0008092 cytoskeletal protein binding
1.89 1.85e-02 GO:0022890 inorganic cation transmembrane transporter activity
1.70 4.30e-02 GO:0022836 gated channel activity
1.66 1.65e-02 GO:0019001 guanyl nucleotide binding
1.66 1.65e-02 GO:0032561 guanyl ribonucleotide binding
1.66 2.32e-02 GO:0005525 GTP binding
1.59 1.98e-03 GO:0019904 protein domain specific binding
1.58 3.86e-06 GO:0019899 enzyme binding
1.58 5.96e-03 GO:0008324 cation transmembrane transporter activity
1.54 7.34e-04 GO:0015075 ion transmembrane transporter activity
1.53 2.27e-05 GO:0022892 substrate-specific transporter activity
1.53 1.82e-04 GO:0022891 substrate-specific transmembrane transporter activity
1.51 3.55e-02 GO:0005509 calcium ion binding
1.50 8.74e-03 GO:0017111 nucleoside-triphosphatase activity