Motif ID: NFIX.p2

Z-value: 1.008


Transcription factors associated with NFIX.p2:

Gene SymbolEntrez IDGene Name
Nfix 18032 nuclear factor I/X

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfixchr8_-_872961720.467.4e-11Click!


Activity profile for motif NFIX.p2.

activity profile for motif NFIX.p2


Sorted Z-values histogram for motif NFIX.p2

Sorted Z-values for motif NFIX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIX.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_154802144 19.469 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr1_+_154802198 18.381 NM_175460
 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr12_+_30687597 18.188 Pxdn
peroxidasin homolog (Drosophila)
chr1_+_154802091 16.254 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr7_+_138079669 13.731 NM_019564
 Htra1
HtrA serine peptidase 1
chr10_-_79602040 12.757 Dos
downstream of Stk11
chr18_-_33623400 11.616 NM_001109989
 D0H4S114
DNA segment, human D4S114
chr13_-_34222209 10.945 NM_023716
 Tubb2b
tubulin, beta 2B
chr18_-_33623287 10.551 NM_053078
 D0H4S114
DNA segment, human D4S114
chr18_-_33623668 10.386 NM_001109988
 D0H4S114
DNA segment, human D4S114
chr1_+_94728217 10.371 NM_016696
 Gpc1
glypican 1
chr6_-_124807733 9.993 Leprel2
leprecan-like 2
chr17_-_23814399 9.964 Tnfrsf12a
tumor necrosis factor receptor superfamily, member 12a
chr1_+_94728419 9.891 Gpc1
glypican 1
chr17_-_23814415 9.757 NM_001161746
NM_013749
 Tnfrsf12a

tumor necrosis factor receptor superfamily, member 12a

chr10_+_24315247 8.596 NM_010217
 Ctgf
connective tissue growth factor
chr16_-_85173978 8.528 App
amyloid beta (A4) precursor protein
chr16_-_85173851 8.449 App
amyloid beta (A4) precursor protein
chr7_-_52347489 8.444 NM_026555
 Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr7_-_106501642 8.212 NM_001111043
NM_001111044
NM_009825
 Serpinh1


serine (or cysteine) peptidase inhibitor, clade H, member 1



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 25 entries
Enrichment   P-value GO Accession GO Term
4.99 1.88e-02 GO:0045667 regulation of osteoblast differentiation
2.65 3.92e-02 GO:0045664 regulation of neuron differentiation
2.49 3.60e-02 GO:0050767 regulation of neurogenesis
2.46 7.26e-03 GO:0060284 regulation of cell development
2.12 8.60e-04 GO:0048699 generation of neurons
2.10 1.59e-02 GO:0007155 cell adhesion
2.08 1.94e-02 GO:0022610 biological adhesion
2.04 9.99e-06 GO:0007399 nervous system development
2.03 2.52e-03 GO:0022008 neurogenesis
1.89 4.58e-03 GO:0006796 phosphate metabolic process
1.88 4.89e-03 GO:0006793 phosphorus metabolic process
1.74 2.47e-02 GO:0009966 regulation of signal transduction
1.67 1.98e-02 GO:0023051 regulation of signaling
1.55 1.77e-03 GO:0048731 system development
1.54 1.22e-02 GO:0048523 negative regulation of cellular process
1.53 6.07e-03 GO:0048519 negative regulation of biological process
1.53 2.05e-02 GO:0071842 cellular component organization at cellular level
1.50 3.74e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.48 9.52e-03 GO:0048856 anatomical structure development
1.46 2.42e-03 GO:0051179 localization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 28 entries
Enrichment   P-value GO Accession GO Term
2.71 3.58e-04 GO:0019866 organelle inner membrane
2.66 1.18e-03 GO:0005743 mitochondrial inner membrane
2.55 1.21e-04 GO:0005740 mitochondrial envelope
2.51 3.63e-04 GO:0031966 mitochondrial membrane
2.40 1.47e-02 GO:0043025 neuronal cell body
2.31 2.29e-04 GO:0044429 mitochondrial part
2.28 3.18e-02 GO:0044297 cell body
2.14 8.63e-04 GO:0031967 organelle envelope
2.14 1.05e-02 GO:0045202 synapse
2.11 1.25e-03 GO:0031975 envelope
2.11 3.48e-03 GO:0043005 neuron projection
1.94 4.77e-04 GO:0005626 insoluble fraction
1.92 1.19e-03 GO:0005624 membrane fraction
1.90 5.01e-05 GO:0000267 cell fraction
1.85 5.12e-04 GO:0042995 cell projection
1.73 3.17e-03 GO:0031090 organelle membrane
1.69 1.16e-03 GO:0005829 cytosol
1.64 3.35e-03 GO:0005739 mitochondrion
1.48 2.72e-10 GO:0044444 cytoplasmic part
1.45 5.17e-17 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
Enrichment   P-value GO Accession GO Term
2.13 9.38e-03 GO:0008092 cytoskeletal protein binding
2.04 2.86e-02 GO:0019904 protein domain specific binding
1.67 3.06e-03 GO:0030554 adenyl nucleotide binding
1.65 4.70e-03 GO:0032559 adenyl ribonucleotide binding
1.62 1.50e-02 GO:0005524 ATP binding
1.55 1.22e-02 GO:0017076 purine nucleotide binding
1.54 1.79e-02 GO:0032555 purine ribonucleotide binding
1.53 1.83e-02 GO:0032553 ribonucleotide binding
1.51 4.21e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.49 1.22e-02 GO:0000166 nucleotide binding
1.41 1.56e-07 GO:0005515 protein binding
1.27 3.19e-02 GO:0003824 catalytic activity
1.25 7.47e-09 GO:0005488 binding