Motif ID: NHLH1,2.p2

Z-value: 1.656


Transcription factors associated with NHLH1,2.p2:

Gene SymbolEntrez IDGene Name
Nhlh1 18071 nescient helix loop helix 1
Nhlh2 18072 nescient helix loop helix 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nhlh2chr3_+_1018140590.248.8e-04Click!
Nhlh1chr1_-_173987681-0.215.4e-03Click!


Activity profile for motif NHLH1,2.p2.

activity profile for motif NHLH1,2.p2


Sorted Z-values histogram for motif NHLH1,2.p2

Sorted Z-values for motif NHLH1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NHLH1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_91270319 46.074 Olig1
oligodendrocyte transcription factor 1
chr14_-_68742863 29.219 Nefm
neurofilament, medium polypeptide
chr8_+_128519295 28.887 Kcnk1
potassium channel, subfamily K, member 1
chr14_-_13655592 28.833 NM_001042617
NM_012061
Cadps

Ca2+-dependent secretion activator

chr14_-_13655558 27.335 Cadps
Ca2+-dependent secretion activator
chr2_+_158201373 24.092 NM_175692
Snhg11
small nucleolar RNA host gene 11
chr8_+_128519001 23.842 NM_008430
Kcnk1
potassium channel, subfamily K, member 1
chr9_-_53823107 22.035 NM_177769
Elmod1
ELMO domain containing 1
chr12_+_109572514 21.448 NM_010010
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr19_+_47089168 19.621 NM_146100
Ina
internexin neuronal intermediate filament protein, alpha
chrX_-_119510890 19.605 NM_138742
Nap1l3
nucleosome assembly protein 1-like 3
chr4_+_137263376 19.171 Rap1gap
Rap1 GTPase-activating protein
chr1_-_84692750 18.475 NM_152915
Dner
delta/notch-like EGF-related receptor
chr15_+_78744802 17.809 Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr18_+_82723920 17.498 Mbp
myelin basic protein
chr14_-_124026357 17.359 NM_177393
Nalcn
sodium leak channel, non-selective
chr15_+_78744576 17.125 Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr5_-_108978950 16.631 NM_007756
Cplx1
complexin 1
chr7_+_53651811 16.414 NM_008421
NM_001112739
Kcnc1

potassium voltage gated channel, Shaw-related subfamily, member 1

chr4_-_133053867 16.372 Trnp1
TMF1-regulated nuclear protein 1
chrX_+_7496899 16.340 NM_013892
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr7_+_64845887 16.314 NM_001038701
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr4_-_133054355 16.255 NM_001081156
Trnp1
TMF1-regulated nuclear protein 1
chr7_+_4071087 15.146 NM_001001454
NM_001109765
NM_021324
Ttyh1


tweety homolog 1 (Drosophila)


chr8_-_73011217 14.855 NM_182991
Tmem59l
transmembrane protein 59-like
chr9_+_103014463 14.852 Rab6b
RAB6B, member RAS oncogene family
chr15_+_78744862 14.810 Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr18_+_45719464 14.237 Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr7_+_134094045 14.042 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr8_+_46744023 13.835 Sorbs2
sorbin and SH3 domain containing 2
chr18_+_45719732 13.598 NM_080465
Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr12_-_73509925 13.212 NM_153457
Rtn1
reticulon 1
chr4_-_57003214 13.203 NM_001142965
6430704M03Rik
RIKEN cDNA 6430704M03 gene
chr1_-_166387998 13.132 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr9_-_54349409 13.063 NM_172771
Dmxl2
Dmx-like 2
chr2_+_132607398 12.896 Chgb
chromogranin B
chr9_-_53822931 12.812 Elmod1
ELMO domain containing 1
chr2_+_132607408 12.702 Chgb
chromogranin B
chr2_+_90730089 12.617 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr9_-_75459046 12.591 Tmod2
tropomodulin 2
chr9_+_103014374 12.565 NM_173781
Rab6b
RAB6B, member RAS oncogene family
chr10_-_108447894 12.468 Syt1
synaptotagmin I
chr5_-_67009869 12.350 NM_009686
Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr10_-_108447996 12.228 Syt1
synaptotagmin I
chr5_-_67009992 12.075 Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr4_-_154719714 12.050 Prkcz
protein kinase C, zeta
chr11_-_58751993 11.917 Rnf187
ring finger protein 187
chrX_-_159081510 11.914 NM_178256
Reps2
RALBP1 associated Eps domain containing protein 2
chr10_-_108448003 11.871 Syt1
synaptotagmin I
chr8_-_48374715 11.774 Stox2
storkhead box 2
chr7_-_31911884 11.756 NM_011322
Scn1b
sodium channel, voltage-gated, type I, beta
chr2_+_132607432 11.748 Chgb
chromogranin B
chr1_-_84692352 11.633 Dner
delta/notch-like EGF-related receptor
chr7_-_13623543 11.610 NM_001168469
Ube2m
ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)
chrX_+_162676870 11.534 NM_001177961
NM_001177962
NM_023122
Gpm6b


glycoprotein m6b


chr15_+_81641832 11.529 NM_017376
Tef
thyrotroph embryonic factor
chr8_-_112692071 11.507 NM_007586
Calb2
calbindin 2
chr7_-_31911733 11.485 Scn1b
sodium channel, voltage-gated, type I, beta
chr17_-_26338254 11.452 NM_008113
Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr16_-_85173930 11.430 App
amyloid beta (A4) precursor protein
chr7_+_64846558 11.426 Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr19_-_7292086 11.343 NM_007750
Cox8a
cytochrome c oxidase, subunit VIIIa
chr19_-_7292057 11.329 Cox8a
cytochrome c oxidase, subunit VIIIa
chr5_-_34630913 11.240 NM_001015039
Zfyve28
zinc finger, FYVE domain containing 28
chr17_-_26338106 11.239 Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr13_-_47110187 11.156 NM_175340
Nhlrc1
NHL repeat containing 1
chr19_+_6427922 11.135 NM_020253
Nrxn2
neurexin II
chr3_+_13471681 11.129 Ralyl
RALY RNA binding protein-like
chr3_+_107698740 10.980 NM_010360
Gstm5
glutathione S-transferase, mu 5
chr6_-_77929660 10.970 NM_001109764
NM_009819
NM_145732
Ctnna2


catenin (cadherin associated protein), alpha 2


chr12_+_101437735 10.950 NM_009790
Calm1
calmodulin 1
chr9_+_103014445 10.902 Rab6b
RAB6B, member RAS oncogene family
chr3_-_125641429 10.901 NM_011674
Ugt8a
UDP galactosyltransferase 8A
chr12_+_16660245 10.863 NM_008747
Ntsr2
neurotensin receptor 2
chr4_+_53453302 10.810 Slc44a1
solute carrier family 44, member 1
chrX_+_162676903 10.757 Gpm6b
glycoprotein m6b
chr17_+_44215761 10.729 NM_032003
NM_001168620
Enpp5

ectonucleotide pyrophosphatase/phosphodiesterase 5

chr16_-_85173851 10.727 App
amyloid beta (A4) precursor protein
chr15_+_78744328 10.653 NM_020271
Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr16_-_85173918 10.579 App
amyloid beta (A4) precursor protein
chr12_+_16660521 10.577 Ntsr2
neurotensin receptor 2
chr9_+_103014279 10.559 Rab6b
RAB6B, member RAS oncogene family
chr9_-_75458865 10.539 Tmod2
tropomodulin 2
chr16_-_4419586 10.503 NM_009624
Adcy9
adenylate cyclase 9
chr17_+_44215851 10.435 Enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr2_+_90729768 10.430 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr6_+_115085096 10.367 Syn2
synapsin II
chr4_+_129662110 10.339 Bai2
brain-specific angiogenesis inhibitor 2
chr9_-_35365985 10.291 NM_013932
Ddx25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr5_+_137506122 10.225 NM_001039385
Vgf
VGF nerve growth factor inducible
chr17_-_25073897 10.206 NM_001163447
NM_001163448
NM_001163449
NM_001163450
NM_001163451
NM_001163453
NM_013931
Mapk8ip3






mitogen-activated protein kinase 8 interacting protein 3






chr4_+_129985957 10.201 NM_010174
Fabp3
fatty acid binding protein 3, muscle and heart
chr9_+_69137694 10.200 Rora
RAR-related orphan receptor alpha
chr16_-_85173944 10.190 NM_001198823
NM_001198824
NM_001198825
NM_001198826
NM_007471
App




amyloid beta (A4) precursor protein




chr15_+_81641869 10.093 Tef
thyrotroph embryonic factor
chr14_-_55531726 10.092 NM_021551
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr5_-_17866110 10.061 NM_010305
Gnai1
guanine nucleotide binding protein (G protein), alpha inhibiting 1
chr5_+_34326081 10.058 NM_001033458
Gm1673
predicted gene 1673
chr12_+_70994091 10.046 NM_178628
Atl1
atlastin GTPase 1
chr17_+_25854439 9.924 Gng13
guanine nucleotide binding protein (G protein), gamma 13
chr4_-_139802683 9.876 NM_198610
Igsf21
immunoglobin superfamily, member 21
chr7_+_129432810 9.875 Prkcb
protein kinase C, beta
chr11_+_101017307 9.827 Tubg2
tubulin, gamma 2
chrX_-_56387565 9.808 NM_010200
Fgf13
fibroblast growth factor 13
chr19_-_7292009 9.807 Cox8a
cytochrome c oxidase, subunit VIIIa
chr4_+_155068566 9.714 NM_178699
B930041F14Rik
RIKEN cDNA B930041F14 gene
chr16_-_4419805 9.690 Adcy9
adenylate cyclase 9
chrX_-_20498021 9.678 NM_001110780
NM_013680
Syn1

synapsin I

chr13_-_25029458 9.656 NM_172532
Aldh5a1
aldhehyde dehydrogenase family 5, subfamily A1
chr8_-_113917651 9.639 NM_178086
Fa2h
fatty acid 2-hydroxylase
chr7_+_19876447 9.582 NM_001025364
Rtn2
reticulon 2 (Z-band associated protein)
chr2_+_132607013 9.547 NM_007694
Chgb
chromogranin B
chr16_-_85173978 9.482 App
amyloid beta (A4) precursor protein
chr17_+_69506165 9.475 Epb4.1l3
erythrocyte protein band 4.1-like 3
chr13_+_64263131 9.419 NM_019986
Habp4
hyaluronic acid binding protein 4
chr10_-_108447674 9.408 NM_009306
Syt1
synaptotagmin I
chr15_-_33617572 9.320 NM_001085421
Tspyl5
testis-specific protein, Y-encoded-like 5
chr18_+_82754377 9.309 Mbp
myelin basic protein
chr4_+_155068450 9.168 B930041F14Rik
RIKEN cDNA B930041F14 gene
chr16_-_20621287 9.121 NM_028420
Camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr7_-_13623158 9.115 NM_145578
Ube2m
ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)
chr15_-_98638348 8.949 NM_001013741
Ddn
dendrin
chr7_+_64846528 8.941 NM_008071
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr18_+_82723854 8.859 NM_001025251
NM_001025255
NM_001025256
NM_001025258
NM_001025259
NM_001025254
Mbp





myelin basic protein





chr16_+_91270009 8.818 NM_016968
Olig1
oligodendrocyte transcription factor 1
chr8_-_41720091 8.788 NM_001040699
Mtmr7
myotubularin related protein 7
chr2_+_25258568 8.779 NM_008721
Npdc1
neural proliferation, differentiation and control gene 1
chr10_+_77315603 8.766 NM_001162944
Gm10318
predicted gene 10318
chr3_+_138405156 8.720 NM_019571
Tspan5
tetraspanin 5
chr4_-_91066674 8.692 NM_207685
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_-_148558110 8.647 NM_019632
Napb
N-ethylmaleimide sensitive fusion protein attachment protein beta
chr15_+_30102306 8.637 NM_008729
Ctnnd2
catenin (cadherin associated protein), delta 2
chr4_-_124527811 8.590 NM_001142727
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr11_-_86887549 8.570 NM_025638
Gdpd1
glycerophosphodiester phosphodiesterase domain containing 1
chr18_+_82723907 8.552 Mbp
myelin basic protein
chr3_+_31048841 8.503 NM_008770
Cldn11
claudin 11
chr3_+_7366586 8.446 NM_008862
Pkia
protein kinase inhibitor, alpha
chr7_-_52230091 8.306 Cpt1c
carnitine palmitoyltransferase 1c
chr7_-_52230117 8.248 NM_153679
Cpt1c
carnitine palmitoyltransferase 1c
chr18_+_82753560 8.225 Mbp
myelin basic protein
chr9_+_69137659 8.222 Rora
RAR-related orphan receptor alpha
chr9_-_86775282 8.201 Snap91
synaptosomal-associated protein 91
chr7_-_31911754 8.198 Scn1b
sodium channel, voltage-gated, type I, beta
chr2_-_130468507 8.181 NM_197945
Prosapip1
ProSAPiP1 protein
chr11_-_4847968 8.170 NM_010904
Nefh
neurofilament, heavy polypeptide
chr14_-_119324535 8.144 Dzip1
DAZ interacting protein 1
chr10_+_98377759 8.136 NM_026482
Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
chr14_-_46277274 8.090 Ddhd1
DDHD domain containing 1
chr2_-_156817751 8.015 NM_013865
NM_180956
Ndrg3

N-myc downstream regulated gene 3

chr4_+_155068604 7.992 B930041F14Rik
RIKEN cDNA B930041F14 gene
chr6_-_77929543 7.984 Ctnna2
catenin (cadherin associated protein), alpha 2
chr17_+_87506971 7.917 NM_019654
Socs5
suppressor of cytokine signaling 5
chr17_+_24641034 7.887 Caskin1
CASK interacting protein 1
chr9_-_86775154 7.860 NM_013669
Snap91
synaptosomal-associated protein 91
chr19_+_4855128 7.858 NM_019861
Ctsf
cathepsin F
chr1_-_46910333 7.828 NM_172653
Slc39a10
solute carrier family 39 (zinc transporter), member 10
chr1_+_160292470 7.818 NM_007495
Astn1
astrotactin 1
chr7_-_52230179 7.786 Cpt1c
carnitine palmitoyltransferase 1c
chr8_-_75877407 7.781 Large
like-glycosyltransferase
chr11_-_74424353 7.716 Rap1gap2
RAP1 GTPase activating protein 2
chr8_-_87461251 7.711 NM_019945
Mast1
microtubule associated serine/threonine kinase 1
chr17_+_74154214 7.705 Ehd3
EH-domain containing 3
chr18_+_82754829 7.690 Mbp
myelin basic protein
chr8_-_48374755 7.684 NM_001114311
Stox2
storkhead box 2
chr14_-_46277772 7.634 Ddhd1
DDHD domain containing 1
chr19_-_45890238 7.601 NM_030716
NM_145703
NM_145704
Kcnip2


Kv channel-interacting protein 2


chr11_-_59263437 7.551 NM_144521
Snap47
synaptosomal-associated protein, 47
chr7_+_17530050 7.529 Pnmal2
PNMA-like 2
chr15_+_74394184 7.527 Bai1
brain-specific angiogenesis inhibitor 1
chr6_-_92484838 7.526 NM_001134459
Prickle2
prickle homolog 2 (Drosophila)
chr2_+_3035629 7.501 NM_001081161
Fam171a1
family with sequence similarity 171, member A1
chr1_-_166388431 7.494 NM_009721
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr9_-_75458954 7.429 Tmod2
tropomodulin 2
chr13_+_48356795 7.370 NM_031166
Id4
inhibitor of DNA binding 4
chr17_+_46390828 7.356 NM_001111142
Gm88
predicted gene 88
chr7_+_17529961 7.352 NM_001099636
Pnmal2
PNMA-like 2
chr2_+_164312087 7.345 Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr17_+_43938887 7.333 Rcan2
regulator of calcineurin 2
chr17_-_37160143 7.296 Mog
myelin oligodendrocyte glycoprotein
chr19_+_47089736 7.296 Ina
internexin neuronal intermediate filament protein, alpha
chr2_+_25258653 7.292 Npdc1
neural proliferation, differentiation and control gene 1
chr2_+_157387284 7.225 Nnat
neuronatin
chr3_+_14886253 7.224 NM_009801
Car2
carbonic anhydrase 2
chr4_-_154719834 7.218 NM_001039079
Prkcz
protein kinase C, zeta
chr9_+_106356125 7.198 NM_021567
Pcbp4
poly(rC) binding protein 4
chr2_+_97306600 7.185


chr6_-_77929685 7.181 Ctnna2
catenin (cadherin associated protein), alpha 2
chr11_-_120645428 7.172 NM_009053
Rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr15_-_58654964 7.132 NM_175212
Tmem65
transmembrane protein 65
chr17_+_74154180 7.117 NM_020578
Ehd3
EH-domain containing 3
chr13_-_25361773 7.101 NM_009513
Nrsn1
neurensin 1
chr4_-_57002965 7.002 6430704M03Rik
RIKEN cDNA 6430704M03 gene
chr16_+_17276384 6.990 NM_177473
Tmem191c
transmembrane protein 191C
chr18_-_60783889 6.988 Synpo
synaptopodin
chr6_+_107479719 6.981 NM_008516
Lrrn1
leucine rich repeat protein 1, neuronal
chr14_-_46277816 6.964 NM_001039106
NM_001042719
NM_176845
Ddhd1


DDHD domain containing 1


chr19_+_10525829 6.961


chrX_+_100551808 6.936 NM_009767
Chic1
cysteine-rich hydrophobic domain 1
chr5_+_27143896 6.917 NM_010075
Dpp6
dipeptidylpeptidase 6
chr4_+_53453277 6.913 NM_001159633
NM_133891
Slc44a1

solute carrier family 44, member 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.44 3.37e-21 GO:0051179 localization
1.46 1.29e-18 GO:0051234 establishment of localization
1.46 3.88e-18 GO:0006810 transport
1.59 4.74e-11 GO:0007399 nervous system development
2.01 7.93e-08 GO:0031175 neuron projection development
1.60 1.61e-07 GO:0051128 regulation of cellular component organization
1.80 2.18e-07 GO:0030030 cell projection organization
1.29 3.26e-07 GO:0016043 cellular component organization
2.12 3.45e-07 GO:0048812 neuron projection morphogenesis
1.99 6.64e-07 GO:0048858 cell projection morphogenesis
1.58 1.06e-06 GO:0022008 neurogenesis
1.60 1.29e-06 GO:0048699 generation of neurons
1.95 1.92e-06 GO:0032990 cell part morphogenesis
1.33 2.23e-06 GO:0071842 cellular component organization at cellular level
1.78 8.43e-06 GO:0048666 neuron development
1.26 1.02e-05 GO:0071840 cellular component organization or biogenesis
1.43 2.05e-05 GO:0033036 macromolecule localization
1.65 4.63e-05 GO:0030182 neuron differentiation
1.60 6.67e-05 GO:0016192 vesicle-mediated transport
1.52 7.03e-05 GO:0015031 protein transport
1.29 9.04e-05 GO:0071841 cellular component organization or biogenesis at cellular level
2.00 1.46e-04 GO:0007409 axonogenesis
1.89 1.68e-04 GO:0045664 regulation of neuron differentiation
1.95 1.78e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
2.14 1.90e-04 GO:0010975 regulation of neuron projection development
1.50 1.98e-04 GO:0045184 establishment of protein localization
1.44 2.23e-04 GO:0008104 protein localization
1.35 4.89e-04 GO:0023051 regulation of signaling
1.23 5.74e-04 GO:0007275 multicellular organismal development
1.42 7.16e-04 GO:0051641 cellular localization
1.24 7.90e-04 GO:0048856 anatomical structure development
1.41 8.97e-04 GO:0032879 regulation of localization
1.98 1.01e-03 GO:0031344 regulation of cell projection organization
1.60 1.05e-03 GO:0030001 metal ion transport
1.45 1.09e-03 GO:0022607 cellular component assembly
1.21 1.24e-03 GO:0032502 developmental process
2.05 1.32e-03 GO:0042391 regulation of membrane potential
1.44 1.74e-03 GO:0051649 establishment of localization in cell
1.29 1.97e-03 GO:0065008 regulation of biological quality
1.53 2.41e-03 GO:0006812 cation transport
1.47 2.53e-03 GO:0051049 regulation of transport
1.75 2.54e-03 GO:0015672 monovalent inorganic cation transport
1.59 2.66e-03 GO:0032989 cellular component morphogenesis
1.24 3.03e-03 GO:0048731 system development
1.61 3.32e-03 GO:0007010 cytoskeleton organization
1.44 4.73e-03 GO:0006811 ion transport
1.70 4.81e-03 GO:0050767 regulation of neurogenesis
1.98 6.89e-03 GO:0051493 regulation of cytoskeleton organization
1.68 7.00e-03 GO:0019226 transmission of nerve impulse
1.68 7.00e-03 GO:0035637 multicellular organismal signaling
2.23 7.84e-03 GO:0032970 regulation of actin filament-based process
2.24 9.03e-03 GO:0032956 regulation of actin cytoskeleton organization
1.58 1.14e-02 GO:0000902 cell morphogenesis
1.34 1.28e-02 GO:0050790 regulation of catalytic activity
1.29 1.73e-02 GO:0051239 regulation of multicellular organismal process
1.36 1.74e-02 GO:0035556 intracellular signal transduction
1.49 1.76e-02 GO:0071844 cellular component assembly at cellular level
1.78 1.99e-02 GO:0030029 actin filament-based process
1.59 2.10e-02 GO:0044057 regulation of system process
1.79 2.48e-02 GO:0051129 negative regulation of cellular component organization
1.29 2.57e-02 GO:0065009 regulation of molecular function
1.47 2.66e-02 GO:0046907 intracellular transport
1.31 3.24e-02 GO:0009056 catabolic process
1.74 3.33e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.63 3.48e-02 GO:0006886 intracellular protein transport
1.64 3.70e-02 GO:0009894 regulation of catabolic process
1.65 3.95e-02 GO:0000904 cell morphogenesis involved in differentiation
1.96 3.99e-02 GO:0006813 potassium ion transport
1.80 4.42e-02 GO:0044087 regulation of cellular component biogenesis

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.28 2.55e-33 GO:0005737 cytoplasm
1.19 8.18e-27 GO:0005622 intracellular
1.34 1.27e-26 GO:0044444 cytoplasmic part
1.18 8.55e-24 GO:0044424 intracellular part
1.79 4.74e-20 GO:0042995 cell projection
2.13 5.25e-20 GO:0043005 neuron projection
2.03 3.63e-14 GO:0045202 synapse
1.16 4.80e-13 GO:0043229 intracellular organelle
1.16 5.76e-13 GO:0043226 organelle
1.08 1.32e-12 GO:0005623 cell
1.08 1.32e-12 GO:0044464 cell part
2.02 1.29e-11 GO:0044463 cell projection part
1.64 2.33e-11 GO:0005794 Golgi apparatus
2.18 2.41e-10 GO:0030425 dendrite
2.07 2.69e-10 GO:0044297 cell body
2.08 5.20e-10 GO:0043025 neuronal cell body
1.52 1.56e-09 GO:0031090 organelle membrane
1.51 5.24e-09 GO:0000267 cell fraction
1.99 1.06e-08 GO:0044456 synapse part
2.11 2.71e-08 GO:0030424 axon
1.14 2.85e-08 GO:0016020 membrane
1.14 3.00e-08 GO:0043231 intracellular membrane-bounded organelle
1.14 3.25e-08 GO:0043227 membrane-bounded organelle
1.53 1.76e-07 GO:0005626 insoluble fraction
1.94 8.45e-07 GO:0048471 perinuclear region of cytoplasm
1.95 1.01e-06 GO:0044431 Golgi apparatus part
1.22 2.40e-06 GO:0071944 cell periphery
1.51 2.83e-06 GO:0005624 membrane fraction
1.60 4.21e-06 GO:0030054 cell junction
1.37 7.50e-06 GO:0005739 mitochondrion
2.38 7.60e-06 GO:0033267 axon part
1.37 7.72e-06 GO:0005829 cytosol
1.22 1.08e-05 GO:0005886 plasma membrane
1.48 1.27e-04 GO:0031982 vesicle
1.29 2.37e-04 GO:0044459 plasma membrane part
1.68 4.21e-04 GO:0005625 soluble fraction
1.47 4.51e-04 GO:0031410 cytoplasmic vesicle
1.61 7.93e-04 GO:0031966 mitochondrial membrane
1.60 9.06e-04 GO:0005740 mitochondrial envelope
1.92 2.56e-03 GO:0031252 cell leading edge
1.49 3.17e-03 GO:0044429 mitochondrial part
1.16 3.18e-03 GO:0044422 organelle part
2.04 3.47e-03 GO:0019717 synaptosome
2.23 4.30e-03 GO:0008021 synaptic vesicle
1.39 7.00e-03 GO:0012505 endomembrane system
1.15 7.32e-03 GO:0044446 intracellular organelle part
1.27 1.03e-02 GO:0005856 cytoskeleton
1.43 1.12e-02 GO:0031975 envelope
1.19 1.25e-02 GO:0043234 protein complex
1.10 1.52e-02 GO:0044425 membrane part
2.34 1.80e-02 GO:0043197 dendritic spine
1.41 2.22e-02 GO:0031967 organelle envelope
2.23 2.23e-02 GO:0042383 sarcolemma
1.86 2.36e-02 GO:0000139 Golgi membrane
6.11 2.48e-02 GO:0033180 proton-transporting V-type ATPase, V1 domain
1.31 2.54e-02 GO:0005783 endoplasmic reticulum
2.21 2.80e-02 GO:0030427 site of polarized growth
2.28 2.96e-02 GO:0044309 neuron spine
2.18 3.50e-02 GO:0030027 lamellipodium
1.55 4.25e-02 GO:0019866 organelle inner membrane
1.57 4.27e-02 GO:0005743 mitochondrial inner membrane
1.85 4.75e-02 GO:0030136 clathrin-coated vesicle
4.01 4.94e-02 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.27 1.82e-17 GO:0005515 protein binding
1.14 3.98e-13 GO:0005488 binding
1.84 8.21e-10 GO:0008092 cytoskeletal protein binding
2.00 1.54e-07 GO:0003779 actin binding
1.71 2.74e-06 GO:0008324 cation transmembrane transporter activity
1.78 3.24e-06 GO:0060589 nucleoside-triphosphatase regulator activity
1.76 1.16e-05 GO:0030695 GTPase regulator activity
1.47 4.08e-05 GO:0022892 substrate-specific transporter activity
1.47 7.40e-05 GO:0030234 enzyme regulator activity
1.41 9.97e-05 GO:0005215 transporter activity
1.50 4.03e-04 GO:0015075 ion transmembrane transporter activity
1.85 4.13e-04 GO:0005261 cation channel activity
1.90 1.11e-03 GO:0005096 GTPase activator activity
1.43 2.44e-03 GO:0022891 substrate-specific transmembrane transporter activity
1.24 3.09e-03 GO:0000166 nucleotide binding
2.14 3.13e-03 GO:0005516 calmodulin binding
1.68 3.52e-03 GO:0008047 enzyme activator activity
1.75 4.70e-03 GO:0005083 small GTPase regulator activity
1.26 4.85e-03 GO:0032553 ribonucleotide binding
1.90 5.37e-03 GO:0005244 voltage-gated ion channel activity
1.90 5.37e-03 GO:0022832 voltage-gated channel activity
3.26 5.84e-03 GO:0019905 syntaxin binding
2.07 6.04e-03 GO:0022843 voltage-gated cation channel activity
1.26 6.32e-03 GO:0032555 purine ribonucleotide binding
1.69 8.47e-03 GO:0022836 gated channel activity
1.25 8.88e-03 GO:0017076 purine nucleotide binding
2.07 1.02e-02 GO:0005267 potassium channel activity
1.38 1.03e-02 GO:0022857 transmembrane transporter activity
1.58 1.33e-02 GO:0005216 ion channel activity
1.59 1.37e-02 GO:0032403 protein complex binding
1.25 1.46e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.57 1.70e-02 GO:0022838 substrate-specific channel activity
1.60 2.11e-02 GO:0005525 GTP binding
2.88 2.19e-02 GO:0000149 SNARE binding
1.54 3.18e-02 GO:0015267 channel activity
1.57 3.48e-02 GO:0019001 guanyl nucleotide binding
1.57 3.48e-02 GO:0032561 guanyl ribonucleotide binding
3.73 3.49e-02 GO:0019829 cation-transporting ATPase activity
1.53 3.51e-02 GO:0022803 passive transmembrane transporter activity
1.32 3.77e-02 GO:0005102 receptor binding
2.41 4.10e-02 GO:0019902 phosphatase binding