Motif ID: NKX2-1,4.p2

Z-value: 0.993


Transcription factors associated with NKX2-1,4.p2:

Gene SymbolEntrez IDGene Name
Nkx2-1 21869 NK2 homeobox 1
Nkx2-4 228731 NK2 transcription factor related, locus 4 (Drosophila)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx2-1chr12_-_576378940.145.7e-02Click!
Nkx2-4chr2_-_1469110800.102.0e-01Click!


Activity profile for motif NKX2-1,4.p2.

activity profile for motif NKX2-1,4.p2


Sorted Z-values histogram for motif NKX2-1,4.p2

Sorted Z-values for motif NKX2-1,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-1,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_104284572 22.641 NM_172435
P2ry10
purinergic receptor P2Y, G-protein coupled 10
chr18_-_9995729 15.031 Usp14
ubiquitin specific peptidase 14
chr15_-_102062309 14.139 Itgb7
integrin beta 7
chr6_-_122560002 13.990 Gdf3
growth differentiation factor 3
chr7_-_31663995 12.759 NM_009845
Cd22
CD22 antigen
chr10_+_7552260 11.922 NM_172785
Zc3h12d
zinc finger CCCH type containing 12D
chr3_+_116564564 11.465 NM_009146
Frrs1
ferric-chelate reductase 1
chr6_-_122560022 10.996 NM_008108
Gdf3
growth differentiation factor 3
chr15_-_102062331 9.607 NM_013566
Itgb7
integrin beta 7
chr5_-_65323937 9.564 NM_030682
Tlr1
toll-like receptor 1
chr8_-_8666771 9.461 Arglu1
arginine and glutamate rich 1
chr7_-_53971038 8.685 NM_011315
Saa3
serum amyloid A 3
chr15_-_78603874 7.728 NM_008595
Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr15_-_78403110 7.718 NM_009008
Rac2
RAS-related C3 botulinum substrate 2
chr17_+_88382830 7.653 Msh6
mutS homolog 6 (E. coli)
chr10_+_87553816 7.634 NM_029971
Pmch
pro-melanin-concentrating hormone
chr2_-_73291933 7.532 Wipf1
WAS/WASL interacting protein family, member 1
chr2_+_61642509 7.249 NM_009322
Tbr1
T-box brain gene 1
chr13_-_108516475 7.205 Zswim6
zinc finger, SWIM domain containing 6
chr17_-_57333491 7.024 NM_019418
Tnfsf14
tumor necrosis factor (ligand) superfamily, member 14

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
2.27 1.43e-02 GO:0002376 immune system process

Nothing significant found in compartment category.

Nothing significant found in function category.