Motif ID: NKX3-1.p2

Z-value: 1.013


Transcription factors associated with NKX3-1.p2:

Gene SymbolEntrez IDGene Name
Nkx3-1 18095 NK-3 transcription factor, locus 1 (Drosophila)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx3-1chr14_+_69808694-0.305.2e-05Click!


Activity profile for motif NKX3-1.p2.

activity profile for motif NKX3-1.p2


Sorted Z-values histogram for motif NKX3-1.p2

Sorted Z-values for motif NKX3-1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_52484889 22.028 AI593442
expressed sequence AI593442
chr8_+_56040193 21.538 Gpm6a
glycoprotein m6a
chr8_+_56040211 20.623 Gpm6a
glycoprotein m6a
chr13_+_59234737 19.509 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr12_+_110798661 18.733 Meg3
maternally expressed 3
chr13_+_42961598 17.127 Phactr1
phosphatase and actin regulator 1
chr6_-_126658429 16.501


chr12_-_73509537 16.469 Rtn1
reticulon 1
chr8_+_56040080 15.570 NM_153581
Gpm6a
glycoprotein m6a
chr15_-_44584003 13.889 NM_178765
Sybu
syntabulin (syntaxin-interacting)
chr18_+_37663917 13.151 NM_053145
Pcdhb20
protocadherin beta 20
chr17_-_85461840 12.879 Prepl
prolyl endopeptidase-like
chr4_-_109959185 12.550 Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr18_+_37157533 12.518 NM_138661
Pcdha9
protocadherin alpha 9
chr4_-_109959366 12.179 NM_001163399
NM_010488
Elavl4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr4_-_136891931 12.033 Cdc42
cell division cycle 42 homolog (S. cerevisiae)
chr3_-_113277601 11.486 NM_007446
Amy1
amylase 1, salivary
chrX_+_162782484 11.294 NM_001177955
NM_001177956
NM_001177957
NM_001177958
NM_001177959
NM_001177960
Gpm6b





glycoprotein m6b





chr3_-_59024076 11.030 P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr12_+_101447480 10.801 Calm1
calmodulin 1
chr12_+_101447413 10.770 Calm1
calmodulin 1
chr10_+_4978808 10.537 Syne1
synaptic nuclear envelope 1
chr5_-_44162032 10.436 Fbxl5
F-box and leucine-rich repeat protein 5
chr11_-_97372344 10.375 Srcin1
SRC kinase signaling inhibitor 1
chr14_-_71029960 10.313 NM_013514
Epb4.9
erythrocyte protein band 4.9
chrX_-_40627962 10.238 NM_011855
Odz1
odd Oz/ten-m homolog 1 (Drosophila)
chr1_-_79436564 10.110 NM_009129
Scg2
secretogranin II
chr2_-_79748552 9.243 NM_001009978
NM_001009979
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr17_-_90487479 8.970 Nrxn1
neurexin I
chr6_-_92517359 8.713 NM_001134461
Prickle2
prickle homolog 2 (Drosophila)
chr4_-_96258099 8.275 NM_028979
Cyp2j9
cytochrome P450, family 2, subfamily j, polypeptide 9
chr5_-_139606339 8.267 Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr6_-_24905939 8.173 NM_177013
Tmem229a
transmembrane protein 229A
chrX_-_147091911 7.711 NM_001002272
NM_019548
Tro

trophinin

chr8_-_55809700 7.642 NM_001172152
Wdr17
WD repeat domain 17
chr19_+_30020236 7.391 NM_001164724
Il33
interleukin 33
chr19_-_41674337 7.346


chr10_+_20760625 7.324 NM_001177776
Ahi1
Abelson helper integration site 1
chr5_+_29524545 7.257 NM_021470
Rnf32
ring finger protein 32
chr7_+_107423813 7.177 Pgm2l1
phosphoglucomutase 2-like 1
chr11_+_104189978 7.013 Mapt
microtubule-associated protein tau
chr3_+_13946371 7.009 NM_001163329
NM_001163330
Ralyl

RALY RNA binding protein-like

chrX_-_100381703 6.746 Nap1l2
nucleosome assembly protein 1-like 2
chr12_+_110800212 6.646 Meg3
maternally expressed 3
chr7_-_125832234 6.011


chr11_+_97702591 5.954 B230217C12Rik
RIKEN cDNA B230217C12 gene
chr14_+_76354807 5.913 NM_026214
Kctd4
potassium channel tetramerisation domain containing 4
chr18_+_37105758 5.886 NM_138662
Pcdha3
protocadherin alpha 3
chr1_+_9591347 5.884 NM_178399
3110035E14Rik
RIKEN cDNA 3110035E14 gene
chr5_-_104543106 5.857 NM_010097
Sparcl1
SPARC-like 1
chr1_-_42749940 5.825 2610017I09Rik
RIKEN cDNA 2610017I09 gene
chr7_-_91520991 5.610 Arnt2
aryl hydrocarbon receptor nuclear translocator 2
chr2_+_91386476 5.522 NM_001165989
NM_029437
Ckap5

cytoskeleton associated protein 5

chr2_-_79969095 5.480 NM_016744
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr8_-_48437701 5.477 NM_175162
Stox2
storkhead box 2
chr13_-_108516475 5.413 Zswim6
zinc finger, SWIM domain containing 6
chr18_+_37133455 5.221 NM_009957
Pcdha7
protocadherin alpha 7
chr15_-_54751515 5.213 NM_001136077
NM_015744
Enpp2

ectonucleotide pyrophosphatase/phosphodiesterase 2

chr13_+_14722494 5.155 NM_001104646
AW209491
expressed sequence AW209491
chr12_-_42212538 5.105 Lrrn3
leucine rich repeat protein 3, neuronal
chr13_+_14722530 5.075 AW209491
expressed sequence AW209491
chr19_-_21467250 4.997 Gda
guanine deaminase
chr6_-_128493413 4.814 BC048546
cDNA sequence BC048546
chr11_-_72016872 4.706 NM_028963
4933427D14Rik
RIKEN cDNA 4933427D14 gene
chr2_-_24618566 4.684 NM_001042528
NM_007579
Cacna1b

calcium channel, voltage-dependent, N type, alpha 1B subunit

chr7_-_86531587 4.641 Rlbp1
retinaldehyde binding protein 1
chr18_-_23197156 4.561 NM_001161483
Nol4
nucleolar protein 4
chr8_-_113917651 4.500 NM_178086
Fa2h
fatty acid 2-hydroxylase
chr17_+_74898763 4.491 Yipf4
Yip1 domain family, member 4
chr3_-_14778441 4.491 NM_001083957
Car1
carbonic anhydrase 1
chr10_-_80693488 4.487 NM_178662
Atcay
ataxia, cerebellar, Cayman type homolog (human)
chr2_+_97306600 4.454


chr3_+_136566015 4.402 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr18_+_38476622 4.385


chr14_+_80400057 4.364 NM_001030294
Olfm4
olfactomedin 4
chr2_+_128604653 4.350 Mertk
c-mer proto-oncogene tyrosine kinase
chr3_-_32884000 4.310 NM_001163517
Pex5l
peroxisomal biogenesis factor 5-like
chr6_+_143156520 4.283 Etnk1
ethanolamine kinase 1
chr1_+_66368571 4.205 Mtap2
microtubule-associated protein 2
chr13_+_14722520 4.155 NM_134067
AW209491
expressed sequence AW209491
chr9_+_104472090 4.046 NM_028719
Cpne4
copine IV
chr1_-_42724504 4.038 2610017I09Rik
RIKEN cDNA 2610017I09 gene
chr3_-_83967952 4.017 Trim2
tripartite motif-containing 2
chr7_+_107789414 3.983 Rab6
RAB6, member RAS oncogene family
chr10_-_4707228 3.947 NM_011702
Vip
vasoactive intestinal polypeptide
chr9_+_111277323 3.941 Trank1
tetratricopeptide repeat and ankyrin repeat containing 1
chr18_+_69843588 3.930 Tcf4
transcription factor 4
chr17_+_70774131 3.913 NM_027712
NM_177639
Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr12_-_73509668 3.897 Rtn1
reticulon 1
chr2_+_121121189 3.870 NM_001173506
Mtap1a
microtubule-associated protein 1 A
chrY_-_133778 3.860 NM_009570
Zfy1
zinc finger protein 1, Y linked
chrX_+_139997806 3.859 NM_008778
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr11_-_51799215 3.854 Ube2b
ubiquitin-conjugating enzyme E2B, RAD6 homology (S. cerevisiae)
chr3_-_113280650 3.849 NM_001110505
Amy1
amylase 1, salivary
chr2_+_20431673 3.828 NM_029895
NM_178059
Etl4

enhancer trap locus 4

chr11_+_79498993 3.822 Rab11fip4
RAB11 family interacting protein 4 (class II)
chr11_-_36757743 3.749 NM_011856
Odz2
odd Oz/ten-m homolog 2 (Drosophila)
chr3_+_51299646 3.709


chr9_-_73781373 3.701 NM_001081153
Unc13c
unc-13 homolog C (C. elegans)
chr3_-_146432922 3.700 Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr13_+_42776161 3.683 Phactr1
phosphatase and actin regulator 1
chr9_+_32031833 3.652 NM_177379
Arhgap32
Rho GTPase activating protein 32
chr3_+_75878452 3.644 NM_178673
Fstl5
follistatin-like 5
chr7_-_149069070 3.606 Tollip
toll interacting protein
chr8_-_74150754 3.597 Unc13a
unc-13 homolog A (C. elegans)
chr4_-_61179982 3.474 Mup1
major urinary protein 1
chr6_-_87338847 3.441 NM_026860
Gkn3
gastrokine 3
chrX_+_80194208 3.432 NM_007868
Dmd
dystrophin, muscular dystrophy
chr10_+_105907394 3.382 NM_177373
Ppfia2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr3_+_95985065 3.346 NM_022030
Sv2a
synaptic vesicle glycoprotein 2 a
chr11_-_41814008 3.308 NM_008073
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr6_+_90424727 3.301 Klf15
Kruppel-like factor 15
chr12_+_91570569 3.269 Nrxn3
neurexin III
chr8_+_59934719 3.264 NM_009136
Scrg1
scrapie responsive gene 1
chrX_+_109608882 3.210 NM_001168590
NM_026333
2010106E10Rik

RIKEN cDNA 2010106E10 gene

chr14_+_14286471 3.172 NM_001163032
Synpr
synaptoporin
chr4_-_60594469 3.156 Mup1
major urinary protein 1
chr15_-_90764873 3.131 Kif21a
kinesin family member 21A
chr9_-_103129187 3.130 Trf
transferrin
chr5_+_107926763 3.095 NM_001007574
NM_001168557
A830010M20Rik

RIKEN cDNA A830010M20 gene

chr4_-_33010429 3.078 NM_001012450
NM_080471
Ankrd6

ankyrin repeat domain 6

chr16_-_85030543 2.958 App
amyloid beta (A4) precursor protein
chrX_-_100381973 2.892 NM_008671
Nap1l2
nucleosome assembly protein 1-like 2
chr19_+_53214934 2.836 NM_001164099
NM_001164101
Add3

adducin 3 (gamma)

chr6_-_90612275 2.834 Iqsec1
IQ motif and Sec7 domain 1
chr18_+_37127284 2.800 NM_007767
Pcdha6
protocadherin alpha 6
chr10_+_60552061 2.773 NM_025273
Pcbd1
pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1
chr5_-_63157309 2.757 NM_178407
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_155756310 2.736 Glul
glutamate-ammonia ligase (glutamine synthetase)
chr7_-_110976438 2.733 Hbb-b1
hemoglobin, beta adult major chain
chr11_-_50745128 2.727 NM_013744
Zfp354b
zinc finger protein 354B
chr16_+_17045125 2.726 Mapk1
mitogen-activated protein kinase 1
chr5_-_31597792 2.706 NM_022424
Fndc4
fibronectin type III domain containing 4
chr9_+_107948285 2.700 Ip6k1
inositol hexaphosphate kinase 1
chr18_+_43923976 2.693 NM_054038
Scgb3a2
secretoglobin, family 3A, member 2
chr4_-_41464365 2.665 NM_001048005
1110017D15Rik
RIKEN cDNA 1110017D15 gene
chr4_+_45310018 2.664 NM_027266
Rg9mtd3
RNA (guanine-9-) methyltransferase domain containing 3
chr10_+_34018323 2.658 Tspyl4
TSPY-like 4
chr15_-_57309179 2.648 NM_172378
BC026439
cDNA sequence BC026439
chr7_-_16457733 2.639 NM_001113330
Crx
cone-rod homeobox containing gene
chr8_+_115093942 2.628 NM_130457
Cntnap4
contactin associated protein-like 4
chr9_-_40792541 2.627 Crtam
cytotoxic and regulatory T cell molecule
chr12_-_60305853 2.613 Fbxo33
F-box protein 33
chr2_+_14310024 2.601 NM_001012305
Slc39a12
solute carrier family 39 (zinc transporter), member 12
chr15_+_92427539 2.586 NM_001164594
Pdzrn4
PDZ domain containing RING finger 4
chr7_+_51480806 2.563 NM_010639
Klk1
kallikrein 1
chr17_-_23908488 2.554 NM_153791
Flywch1
FLYWCH-type zinc finger 1
chrX_-_73088288 2.518 NM_001166454
Pls3
plastin 3 (T-isoform)
chr18_+_34480612 2.507 Apc
adenomatosis polyposis coli
chr1_+_5073161 2.459 NM_133826
Atp6v1h
ATPase, H+ transporting, lysosomal V1 subunit H
chr3_-_113126814 2.447 NM_001160150
NM_001160151
NM_001160152
NM_001042711
Amy2a4
Amy2a3
Amy2a2
Amy2a5
amylase 2a4
amylase 2a3
amylase 2a2
amylase 2a5
chr18_+_69753035 2.446 Tcf4
transcription factor 4
chr3_-_27795287 2.424 NM_001164437
Tmem212
transmembrane protein 212
chr13_+_27149438 2.417 NM_001163530
NM_011164
Prl

prolactin

chr8_-_47292863 2.406


chr10_+_40657980 2.404 Wasf1
WASP family 1
chr6_+_41304103 2.396 NM_001038996
Try10
trypsin 10
chr2_-_66278870 2.388 NM_018733
Scn1a
sodium channel, voltage-gated, type I, alpha
chr1_-_89283173 2.366


chr12_+_75398460 2.360 NM_198866
Dbpht2
DNA binding protein with his-thr domain
chr17_+_17539635 2.351 NM_025681
Lix1
limb expression 1 homolog (chicken)
chr6_-_148937854 2.346 Dennd5b
DENN/MADD domain containing 5B
chr3_-_113159420 2.345 NM_001160150
NM_001160151
NM_001160152
NM_001042711
Amy2a4
Amy2a3
Amy2a2
Amy2a5
amylase 2a4
amylase 2a3
amylase 2a2
amylase 2a5
chr3_+_95330700 2.322 NM_021281
Ctss
cathepsin S
chr3_+_136333251 2.304 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr3_-_113094211 2.296 NM_001160150
NM_001160151
NM_001160152
NM_001042711
Amy2a4
Amy2a3
Amy2a2
Amy2a5
amylase 2a4
amylase 2a3
amylase 2a2
amylase 2a5
chr11_-_90252228 2.285 NM_172563
Hlf
hepatic leukemia factor
chr17_-_25922419 2.274 Haghl
hydroxyacylglutathione hydrolase-like
chr15_-_8660729 2.269 NM_148938
Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_-_4344470 2.245 Ncoa1
nuclear receptor coactivator 1
chr11_-_62206116 2.243 Ncor1
nuclear receptor co-repressor 1
chr17_-_43639675 2.242 NM_008585
Mep1a
meprin 1 alpha
chr9_-_112090150 2.204 NM_033264
NM_001177615
NM_001177620
NM_028755
Arpp21



cyclic AMP-regulated phosphoprotein, 21



chr15_-_95359136 2.177 NM_016743
Nell2
NEL-like 2 (chicken)
chr5_-_104542751 2.174 Sparcl1
SPARC-like 1
chr4_-_109960078 2.171 NM_001038698
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr9_+_66561492 2.162 NM_178396
Car12
carbonic anyhydrase 12
chr10_+_87553816 2.149 NM_029971
Pmch
pro-melanin-concentrating hormone
chr7_-_116651647 2.145 NM_001170912
NM_181853
Trim66

tripartite motif-containing 66

chr19_-_41151561 2.136 NM_153520
Opalin
oligodendrocytic myelin paranodal and inner loop protein
chr3_-_10197187 2.100 NM_011598
Fabp9
fatty acid binding protein 9, testis
chr4_-_138419379 2.092 NM_001122954
Pla2g5
phospholipase A2, group V
chr18_+_69753146 2.087 Tcf4
transcription factor 4
chr7_-_110976499 2.077 Hbb-b1
hemoglobin, beta adult major chain
chr5_-_44485951 2.066 NM_001163578
NM_001163581
NM_001163582
NM_001163583
NM_001163584
NM_001163585
Prom1





prominin 1





chr5_-_88128419 2.064 NM_009972
Csn2
casein beta
chr3_-_115956312 2.050 NM_022427
Gpr88
G-protein coupled receptor 88
chr18_+_38611212 2.045


chr4_-_60594496 2.030 Mup1
major urinary protein 1
chr3_+_159262144 2.011 NM_029987
Rpe65
retinal pigment epithelium 65
chr10_-_52058305 2.003 Gopc
golgi associated PDZ and coiled-coil motif containing
chr14_-_100548982 2.001 NM_010636
Klf12
Kruppel-like factor 12
chr4_-_134409044 1.997 Tmem57
transmembrane protein 57
chr5_+_34185760 1.996 NM_001081102
NM_001177884
NM_175231
Whsc1


Wolf-Hirschhorn syndrome candidate 1 (human)


chr18_+_37644390 1.989 Pcdhb17
protocadherin beta 17
chr3_-_65940346 1.986 NM_028357
Veph1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr1_+_111880313 1.983 NM_172853
Cdh7
cadherin 7, type 2
chr18_+_80315134 1.979 Pard6g
par-6 partitioning defective 6 homolog gamma (C. elegans)
chr1_-_72583137 1.973 NM_001045533
March4
membrane-associated ring finger (C3HC4) 4
chr3_-_117063793 1.967 NM_177664
D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.