Motif ID: NR1H4.p2

Z-value: 1.603


Transcription factors associated with NR1H4.p2:

Gene SymbolEntrez IDGene Name
Nr1h4 20186 nuclear receptor subfamily 1, group H, member 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr1h4chr10_-_889693710.281.7e-04Click!


Activity profile for motif NR1H4.p2.

activity profile for motif NR1H4.p2


Sorted Z-values histogram for motif NR1H4.p2

Sorted Z-values for motif NR1H4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR1H4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_94407548 35.279 Bhmt
betaine-homocysteine methyltransferase
chr19_-_38199737 32.702 NM_001159487
 Rbp4
retinol binding protein 4, plasma
chr19_-_38199291 32.471 NM_011255
 Rbp4
retinol binding protein 4, plasma
chr19_-_38199036 32.458 Rbp4
retinol binding protein 4, plasma
chr16_+_23146608 32.175 NM_009605
 Adipoq
adiponectin, C1Q and collagen domain containing
chr16_+_23146631 31.186 Adipoq
adiponectin, C1Q and collagen domain containing
chr6_-_124492297 31.027 NM_144938
NM_001097617
 C1s

complement component 1, s subcomponent

chr19_-_38199267 30.971 Rbp4
retinol binding protein 4, plasma
chr7_-_31839825 30.504 NM_052991
NM_194321
 Fxyd1

FXYD domain-containing ion transport regulator 1

chr19_-_38199112 29.614 Rbp4
retinol binding protein 4, plasma
chr7_-_31840647 25.282 NM_019503
NM_052992
 Fxyd1

FXYD domain-containing ion transport regulator 1

chr10_-_76175108 20.920 Col6a1
collagen, type VI, alpha 1
chr17_+_75404893 20.770 Ltbp1
latent transforming growth factor beta binding protein 1
chr11_-_75236018 20.734 Serpinf1
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr11_-_75236012 20.491 Serpinf1
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr4_-_129851941 20.150 Tinagl1
tubulointerstitial nephritis antigen-like 1
chr17_+_75404865 20.125 NM_019919
 Ltbp1
latent transforming growth factor beta binding protein 1
chr10_-_76188683 20.000 NM_009933
 Col6a1
collagen, type VI, alpha 1
chr4_-_129852030 19.297 NM_001168333
 Tinagl1
tubulointerstitial nephritis antigen-like 1
chr11_-_75236085 19.229 NM_011340
 Serpinf1
serine (or cysteine) peptidase inhibitor, clade F, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
Enrichment   P-value GO Accession GO Term
12.50 4.18e-02 GO:0009698 phenylpropanoid metabolic process
10.94 2.57e-03 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
7.69 1.01e-02 GO:0019439 aromatic compound catabolic process
5.10 3.81e-02 GO:0043401 steroid hormone mediated signaling pathway
4.41 2.76e-02 GO:0071383 cellular response to steroid hormone stimulus
2.39 2.81e-02 GO:0032787 monocarboxylic acid metabolic process
2.27 2.71e-05 GO:0006082 organic acid metabolic process
2.19 1.95e-04 GO:0019752 carboxylic acid metabolic process
2.19 1.95e-04 GO:0043436 oxoacid metabolic process
2.14 4.51e-04 GO:0042180 cellular ketone metabolic process
2.08 1.71e-02 GO:0072358 cardiovascular system development
2.08 1.71e-02 GO:0072359 circulatory system development
1.98 1.16e-03 GO:0055114 oxidation-reduction process
1.63 1.34e-03 GO:0044281 small molecule metabolic process
1.22 6.96e-03 GO:0008152 metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 18 of 18 entries
Enrichment   P-value GO Accession GO Term
17.50 4.83e-06 GO:0042612 MHC class I protein complex
7.96 4.50e-03 GO:0042611 MHC protein complex
3.40 1.69e-02 GO:0044455 mitochondrial membrane part
2.34 3.18e-04 GO:0031966 mitochondrial membrane
2.31 7.45e-03 GO:0005743 mitochondrial inner membrane
2.29 2.21e-02 GO:0005578 proteinaceous extracellular matrix
2.25 1.25e-02 GO:0031012 extracellular matrix
2.24 9.01e-04 GO:0005740 mitochondrial envelope
2.21 3.03e-02 GO:0005792 microsome
2.19 1.94e-02 GO:0019866 organelle inner membrane
2.15 4.64e-02 GO:0042598 vesicular fraction
2.01 3.18e-03 GO:0044429 mitochondrial part
1.73 3.87e-03 GO:0044421 extracellular region part
1.66 1.13e-05 GO:0005576 extracellular region
1.61 9.75e-04 GO:0005739 mitochondrion
1.59 1.33e-02 GO:0031090 organelle membrane
1.33 5.80e-06 GO:0044444 cytoplasmic part
1.16 4.96e-02 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
Enrichment   P-value GO Accession GO Term
6.25 4.06e-02 GO:0070330 aromatase activity
5.50 1.57e-03 GO:0003707 steroid hormone receptor activity
5.39 1.93e-03 GO:0004879 ligand-dependent nuclear receptor activity
3.01 4.97e-03 GO:0031406 carboxylic acid binding
2.68 1.82e-02 GO:0005506 iron ion binding
2.55 5.60e-03 GO:0048037 cofactor binding
2.39 2.93e-04 GO:0008289 lipid binding
1.50 1.87e-02 GO:0046914 transition metal ion binding
1.38 9.56e-04 GO:0043167 ion binding
1.38 1.16e-03 GO:0043169 cation binding
1.37 1.99e-03 GO:0046872 metal ion binding
1.26 9.07e-03 GO:0003824 catalytic activity
1.14 1.58e-02 GO:0005488 binding