• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: NRF1.p2

Z-value: 4.836

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_-_90727466	36.566	NM_025642	2610039C10Rik	RIKEN cDNA 2610039C10 gene
chr7_-_4610551	35.360	NM_172894	Ppp6r1	protein phosphatase 6, regulatory subunit 1
chr11_-_33063024	34.747	NM_008722	Npm1	nucleophosmin 1
chr11_-_69734838	33.796	NM_001166589 NM_001166591 NM_181582	Eif5a	eukaryotic translation initiation factor 5A
chr7_-_4610179	33.369		Ppp6r1	protein phosphatase 6, regulatory subunit 1
chr7_+_52071622	31.665	NM_001171024 NM_053074	Nup62-il4i1 Nup62	Nup62-Il4i1 protein nucleoporin 62
chr7_+_52071438	31.536		Nup62	nucleoporin 62
chr5_-_138227400	30.204		Mepce	methylphosphate capping enzyme
chr8_+_125091889	29.943	NM_026014	Cdt1	chromatin licensing and DNA replication factor 1
chr2_-_172195998	29.767	NM_011497	Aurka	aurora kinase A
chr11_-_40546863	29.705	NM_013552	Hmmr	hyaluronan mediated motility receptor (RHAMM)
chr17_-_24388262	29.492	NM_007634	Ccnf	cyclin F
chr8_+_125091925	29.437		Cdt1	chromatin licensing and DNA replication factor 1
chr6_+_66485368	28.241	NM_019499	Mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)
chr11_+_40547368	27.147		Nudcd2	NudC domain containing 2
chr11_+_97177029	26.553	NM_025927	Mrpl45	mitochondrial ribosomal protein L45
chr4_+_55362949	26.449		Rad23b	RAD23b homolog (S. cerevisiae)
chr5_+_107393340	26.382	NM_009863	Cdc7	cell division cycle 7 (S. cerevisiae)
chr11_-_34647110	26.323	NM_027411	Ccdc99	coiled-coil domain containing 99
chr15_+_84753875	26.291		Nup50	nucleoporin 50
chr13_-_68720969	25.974	NM_172480	Mtrr	5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr19_-_7315495	25.761	NM_027643	Naa40	N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr17_-_53828596	25.572	NM_028232	Sgol1	shugoshin-like 1 (S. pombe)
chr11_-_69735459	24.338	NM_001166593	Eif5a	eukaryotic translation initiation factor 5A
chr10_-_80261226	24.265	NM_023900	Plekhj1	pleckstrin homology domain containing, family J member 1
chr17_+_35031503	24.055	NM_198886	Zbtb12	zinc finger and BTB domain containing 12
chr11_+_100981384	23.775	NM_134024	Tubg1	tubulin, gamma 1
chr5_-_121902350	23.361	NM_026129	Erp29	endoplasmic reticulum protein 29
chr11_+_40547143	23.329	NM_026023	Nudcd2	NudC domain containing 2
chr6_-_126889539	22.898	NM_009013	Rad51ap1	RAD51 associated protein 1
chr15_+_84753817	22.672	NM_016714	Nup50	nucleoporin 50
chr2_-_126959605	21.991	NM_144818	Ncaph	non-SMC condensin I complex, subunit H
chr15_-_51823257	21.927	NM_009009	Rad21	RAD21 homolog (S. pombe)
chr15_+_103070840	21.459	NM_001039129 NM_010447	Hnrnpa1	heterogeneous nuclear ribonucleoprotein A1
chr15_-_102501463	21.184	NM_026468	Atp5g2	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)
chr17_+_35118956	21.139	NM_030597	Lsm2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr10_+_127669118	20.993	NM_001136082 NM_001164080 NM_001164081	Timeless	timeless homolog (Drosophila)
chr13_-_14705281	20.873	NM_029271	Mrpl32	mitochondrial ribosomal protein L32
chr11_+_3190334	20.798	NM_019574	Patz1	POZ (BTB) and AT hook containing zinc finger 1
chr5_-_138227888	20.669	NM_144913	Mepce	methylphosphate capping enzyme
chr6_-_86683191	20.471		Gmcl1	germ cell-less homolog 1 (Drosophila)
chr10_+_127669154	20.451		Timeless	timeless homolog (Drosophila)
chr1_-_167932735	20.228	NM_011137 NM_198932	Pou2f1	POU domain, class 2, transcription factor 1
chr4_+_140703968	20.029		Fbxo42	F-box protein 42
chr17_+_35118792	19.998	NM_001110101	Lsm2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr3_+_40603872	19.842	NM_011495	Plk4	polo-like kinase 4 (Drosophila)
chr11_-_69734709	19.827	NM_001166595	Eif5a	eukaryotic translation initiation factor 5A
chr3_+_79433000	19.759	NM_029482	4930579G24Rik	RIKEN cDNA 4930579G24 gene
chr11_-_11708917	19.729	NM_001163359 NM_001163360 NM_021891	Fignl1	fidgetin-like 1
chr6_+_83028608	19.637		Pcgf1	polycomb group ring finger 1
chr6_-_86683330	19.527	NM_011818	Gmcl1	germ cell-less homolog 1 (Drosophila)
chr10_+_79727708	19.262	NM_001122604 NM_001122605 NM_133188	Dazap1	DAZ associated protein 1
chr18_-_70632130	19.123	NM_172967	4930503L19Rik	RIKEN cDNA 4930503L19 gene
chr19_-_5964187	18.708	NM_001164057 NM_008893	Pola2	polymerase (DNA directed), alpha 2
chr2_-_169956719	18.437	NM_001033299	Zfp217	zinc finger protein 217
chr5_+_33361386	18.166	NM_011738	Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr6_+_83028337	18.004	NM_197992	Pcgf1	polycomb group ring finger 1
chr5_-_137943570	17.989	NM_028753	Pop7	processing of precursor 7, ribonuclease P family, (S. cerevisiae)
chr2_-_156832762	17.917	NM_025853	Dsn1	DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr5_-_77738960	17.736	NM_019836	2610024G14Rik	RIKEN cDNA 2610024G14 gene
chr17_-_23810808	17.512		Thoc6	THO complex 6 homolog (Drosophila)
chr19_+_5490454	17.299	NM_007687	Cfl1	cofilin 1, non-muscle
chr17_+_56812647	17.226	NM_027933	Ranbp3	RAN binding protein 3
chr13_-_22134795	17.157	NM_178186	Hist1h2ag Hist1h2ai	histone cluster 1, H2ag histone cluster 1, H2ai
chr17_-_23810736	17.056	NM_001008425	Thoc6	THO complex 6 homolog (Drosophila)
chr4_-_131901576	17.032	NM_001197082 NM_133878	Rcc1	regulator of chromosome condensation 1
chr12_+_79962662	17.000		Eif2s1	eukaryotic translation initiation factor 2, subunit 1 alpha
chr12_+_101122706	16.946	NM_028354	Tdp1	tyrosyl-DNA phosphodiesterase 1
chr7_+_31017305	16.926		Polr2i	polymerase (RNA) II (DNA directed) polypeptide I
chr17_+_35035898	16.792	NM_145830	Ehmt2	euchromatic histone lysine N-methyltransferase 2
chr16_+_18498805	16.767	NM_001081682	Gnb1l	guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr16_+_10412017	16.669	NM_011955	Nubp1	nucleotide binding protein 1
chr1_-_193399412	16.323	NM_029766	Dtl	denticleless homolog (Drosophila)
chr7_+_13610047	16.276		Trim28	tripartite motif-containing 28
chr10_+_79144868	16.250	NM_177613	Cdc34	cell division cycle 34 homolog (S. cerevisiae)
chr6_+_42214999	16.105	NM_007610	Casp2	caspase 2
chr2_-_128769687	15.961	NM_020594	Zc3h8	zinc finger CCCH type containing 8
chr18_-_70632157	15.909		4930503L19Rik	RIKEN cDNA 4930503L19 gene
chr15_-_51823107	15.828		Rad21	RAD21 homolog (S. pombe)
chr11_+_77796215	15.517	NM_174852	Phf12	PHD finger protein 12
chrX_+_7455387	15.486	NM_138606	Pim2	proviral integration site 2
chr3_-_89222140	15.329	NM_016904	Cks1b	CDC28 protein kinase 1b
chr9_+_21420612	15.177	NM_001174078 NM_001174079 NM_011417	Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr5_-_136410488	15.143	NM_018871	Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr15_+_78744862	15.126		Pdxp	pyridoxal (pyridoxine, vitamin B6) phosphatase
chr10_-_80260968	15.114		Plekhj1	pleckstrin homology domain containing, family J member 1
chr2_+_120393393	15.090	NM_001177792 NM_001177793 NM_009222	Snap23	synaptosomal-associated protein 23
chr17_-_75951137	15.059	NM_133747	Fam98a	family with sequence similarity 98, member A
chr11_+_86358491	15.056	NM_001199045 NM_001199046 NM_001199047 NM_019756	Tubd1	tubulin, delta 1
chr11_-_34647016	15.042		Ccdc99	coiled-coil domain containing 99
chr2_+_172825687	15.008		Rae1	RAE1 RNA export 1 homolog (S. pombe)
chr10_-_116661519	14.928	NM_026570	Yeats4	YEATS domain containing 4
chr4_+_55362895	14.859	NM_009011	Rad23b	RAD23b homolog (S. cerevisiae)
chr2_-_174298383	14.784		Slmo2	slowmo homolog 2 (Drosophila)
chr5_+_33361571	14.756		Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr15_-_94373918	14.676	NM_172437	Pus7l	pseudouridylate synthase 7 homolog (S. cerevisiae)-like
chr2_+_172825651	14.446		Rae1	RAE1 RNA export 1 homolog (S. pombe)
chr4_+_140703847	14.321		Fbxo42	F-box protein 42
chr16_+_18498963	14.300	NM_023120	Gnb1l	guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr10_-_126959446	14.281	NM_028230	Shmt2	serine hydroxymethyltransferase 2 (mitochondrial)
chr8_+_13338741	14.238		Tfdp1	transcription factor Dp 1
chr10_+_58786043	14.236	NM_011030	P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
chr7_-_134160552	14.155		2900092E17Rik	RIKEN cDNA 2900092E17 gene
chr6_+_113554785	14.012		6720456B07Rik	RIKEN cDNA 6720456B07 gene
chr8_-_109948891	13.931	NM_026277	Nob1	NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr7_+_133792793	13.833	NM_029339	Ccdc101	coiled-coil domain containing 101
chr10_-_59465798	13.716		Anapc16	anaphase promoting complex subunit 16
chr8_-_86781160	13.693	NM_026423	Mri1	methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
chr11_-_70468130	13.595	NM_011072	Pfn1	profilin 1
chr19_+_8797973	13.555		Snhg1	small nucleolar RNA host gene (non-protein coding) 1
chr5_-_122821971	13.509	NM_026883	1500011H22Rik	RIKEN cDNA 1500011H22 gene
chr14_+_70945119	13.495		Reep4	receptor accessory protein 4
chr10_-_79862025	13.482		Mbd3	methyl-CpG binding domain protein 3
chr8_-_82235601	13.439	NM_015751	Abce1	ATP-binding cassette, sub-family E (OABP), member 1
chr13_-_23663006	13.385	NM_178187	Hist1h2ae	histone cluster 1, H2ae
chr17_-_48548973	13.289	NM_001110832 NM_010913	Nfya	nuclear transcription factor-Y alpha
chr7_-_134160864	13.253	NM_030240	2900092E17Rik	RIKEN cDNA 2900092E17 gene
chr11_+_69794546	13.248	NM_026017	Ctdnep1	CTD nuclear envelope phosphatase 1
chr3_-_36470904	13.095	NM_009828	Ccna2	cyclin A2
chr7_+_87439301	13.076	NM_145150	Prc1	protein regulator of cytokinesis 1
chr10_-_80841099	13.069	NM_019757	Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)
chr13_-_23775827	13.013	NM_178189	Hist1h2ac	histone cluster 1, H2ac
chr8_+_34842513	13.005	NM_026584	Gtf2e2	general transcription factor II E, polypeptide 2 (beta subunit)
chr15_+_78744802	12.996		Pdxp	pyridoxal (pyridoxine, vitamin B6) phosphatase
chr15_-_11329374	12.990		Tars	threonyl-tRNA synthetase
chr1_+_55145132	12.947		Hspe1	heat shock protein 1 (chaperonin 10)
chr7_-_52722144	12.920	NM_007527	Bax	BCL2-associated X protein
chr10_-_59465725	12.803		Anapc16	anaphase promoting complex subunit 16
chr3_-_68848657	12.797	NM_025863	Trim59	tripartite motif-containing 59
chr9_-_21092394	12.791	NM_145416	Kri1	KRI1 homolog (S. cerevisiae)
chr13_+_73604668	12.791		Lpcat1	lysophosphatidylcholine acyltransferase 1
chr15_-_11329310	12.776		Tars	threonyl-tRNA synthetase
chr11_-_72951771	12.769	NM_010353	Gsg2	germ cell-specific gene 2
chr10_+_74674793	12.754	NM_153406	Specc1l	sperm antigen with calponin homology and coiled-coil domains 1-like
chr15_-_11329385	12.740	NM_033074	Tars	threonyl-tRNA synthetase
chr11_-_70468061	12.704		Pfn1	profilin 1
chr17_-_6317399	12.683	NM_001166629	Dynlt1c Dynlt1a	dynein light chain Tctex-type 1C dynein light chain Tctex-type 1A
chr15_-_11329379	12.661		Tars	threonyl-tRNA synthetase
chr3_-_36470845	12.630		Ccna2	cyclin A2
chr18_+_80403593	12.529	NM_001042408	Txnl4a	thioredoxin-like 4A
chr5_+_33361479	12.495		Ywhah	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr14_+_102053172	12.491	NM_016723	Uchl3	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr10_-_126959397	12.489		Shmt2	serine hydroxymethyltransferase 2 (mitochondrial)
chr3_-_68848588	12.467		Trim59	tripartite motif-containing 59
chr7_+_29595894	12.453	NM_177301	Hnrnpl	heterogeneous nuclear ribonucleoprotein L
chrX_+_130842622	12.398		Cenpi	centromere protein I
chr3_+_88101037	12.365	NM_009836	Cct3	chaperonin containing Tcp1, subunit 3 (gamma)
chr18_+_44540137	12.351	NM_027490	Dcp2	DCP2 decapping enzyme homolog (S. cerevisiae)
chrX_+_130842701	12.314	NM_145924	Cenpi	centromere protein I
chr8_-_23704176	12.193	NM_001198998 NM_011696	Vdac3	voltage-dependent anion channel 3
chr8_+_90661746	12.183	NM_172757	Heatr3	HEAT repeat containing 3
chr14_-_47896531	12.137	NM_172598	Wdhd1	WD repeat and HMG-box DNA binding protein 1
chr19_+_8894752	12.119		Hnrnpul2	heterogeneous nuclear ribonucleoprotein U-like 2
chr13_+_21902235	12.100	NM_178185 NM_001177544	Hist1h2ah Hist1h2ap Hist1h2ai Hist1h2ao	histone cluster 1, H2ah histone cluster 1, H2ap histone cluster 1, H2ai histone cluster 1, H2ao
chr1_-_55144687	12.091	NM_010477	Hspd1	heat shock protein 1 (chaperonin)
chr9_-_57493393	12.085		Csk	c-src tyrosine kinase
chr11_+_57917712	12.082		Cnot8	CCR4-NOT transcription complex, subunit 8
chr8_-_122082604	12.032	NM_001167910 NM_019709	Mbtps1	membrane-bound transcription factor peptidase, site 1
chr1_-_55144637	12.006		Hspd1	heat shock protein 1 (chaperonin)
chr8_-_72758275	11.979	NM_133972	Armc6	armadillo repeat containing 6
chr12_-_111934448	11.903		Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1
chr14_+_32150060	11.881		Capn7	calpain 7
chr5_-_122822329	11.873		1500011H22Rik	RIKEN cDNA 1500011H22 gene
chr14_-_47896464	11.867		Wdhd1	WD repeat and HMG-box DNA binding protein 1
chr5_-_136410216	11.804		Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr8_-_72758007	11.789		Armc6	armadillo repeat containing 6
chr13_-_22127419	11.768	NM_175659	Hist1h2ah	histone cluster 1, H2ah
chr3_-_36470882	11.768		Ccna2	cyclin A2
chr5_-_145726643	11.765	NM_001038627 NM_029438	Smurf1	SMAD specific E3 ubiquitin protein ligase 1
chr13_+_51740804	11.758		Cks2	CDC28 protein kinase regulatory subunit 2
chr13_+_51740600	11.753	NM_025415	Cks2	CDC28 protein kinase regulatory subunit 2
chr7_+_13609719	11.671		Trim28	tripartite motif-containing 28
chr4_-_120242805	11.608	NM_016748	Ctps	cytidine 5'-triphosphate synthase
chr6_-_83267540	11.575	NM_008638	Mthfd2	methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
chr5_+_122822505	11.534	NM_024216	Gpn3	GPN-loop GTPase 3
chr15_-_64143929	11.460		Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1
chr9_-_53056152	11.414	NM_029936	Ddx10	DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr18_+_6765174	11.412	NM_181070	Rab18	RAB18, member RAS oncogene family
chr5_+_125343060	11.404	NM_001081750	Zfp664	zinc finger protein 664
chr10_-_117147722	11.376		Mdm2	transformed mouse 3T3 cell double minute 2
chr7_-_29766721	11.348	NM_028659	Eif3k	eukaryotic translation initiation factor 3, subunit K
chr7_+_25332168	11.254	NM_009532	Xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1
chr18_-_74367362	11.226		Ska1	spindle and kinetochore associated complex subunit 1
chr17_-_71876150	11.205	NM_023294	Ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr3_+_68808879	11.159	NM_133786	Smc4	structural maintenance of chromosomes 4
chr7_-_134160841	11.153		2900092E17Rik	RIKEN cDNA 2900092E17 gene
chr17_-_71876127	11.146		Ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr3_-_35831775	11.111		Dcun1d1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)
chr2_+_172196161	11.087		Cstf1	cleavage stimulation factor, 3' pre-RNA, subunit 1
chr7_-_16973112	11.080	NM_019748	Sae1	SUMO1 activating enzyme subunit 1
chr1_-_46910333	11.057	NM_172653	Slc39a10	solute carrier family 39 (zinc transporter), member 10
chr11_+_118884275	11.052	NM_007623	Cbx2	chromobox homolog 2 (Drosophila Pc class)
chr6_+_92041408	11.043	NM_011630	Nr2c2	nuclear receptor subfamily 2, group C, member 2
chr1_+_136859153	11.040	NM_026024	Ube2t	ubiquitin-conjugating enzyme E2T (putative)
chr18_+_80403581	11.019	NM_178604	Txnl4a	thioredoxin-like 4A
chr2_-_174298441	10.996	NM_025531	Slmo2	slowmo homolog 2 (Drosophila)
chr8_+_34842810	10.979	NM_001167922	Gtf2e2	general transcription factor II E, polypeptide 2 (beta subunit)
chr11_-_86071041	10.974	NM_027421	Ints2	integrator complex subunit 2
chr1_+_74552600	10.967	NM_021383	Rqcd1	rcd1 (required for cell differentiation) homolog 1 (S. pombe)
chr10_+_21015762	10.910	NM_001042593 NM_001145209 NM_019702	Hbs1l	Hbs1-like (S. cerevisiae)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.82	7.78e-83	GO:0044260	cellular macromolecule metabolic process
1.60	1.14e-69	GO:0044237	cellular metabolic process
1.69	1.33e-67	GO:0043170	macromolecule metabolic process
2.05	2.38e-65	GO:0090304	nucleic acid metabolic process
1.92	2.35e-62	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.82	6.63e-57	GO:0034641	cellular nitrogen compound metabolic process
2.00	1.54e-55	GO:0010467	gene expression
1.52	1.20e-53	GO:0044238	primary metabolic process
1.78	3.29e-53	GO:0006807	nitrogen compound metabolic process
1.46	6.92e-52	GO:0008152	metabolic process
2.01	5.20e-51	GO:0016070	RNA metabolic process
1.83	3.69e-36	GO:0034645	cellular macromolecule biosynthetic process
1.82	3.12e-35	GO:0009059	macromolecule biosynthetic process
1.66	2.30e-31	GO:0044249	cellular biosynthetic process
2.83	8.56e-30	GO:0006396	RNA processing
1.63	8.80e-30	GO:0009058	biosynthetic process
1.76	2.99e-27	GO:0044267	cellular protein metabolic process
1.63	6.46e-24	GO:0010468	regulation of gene expression
1.65	6.65e-24	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.69	3.59e-23	GO:0071841	cellular component organization or biogenesis at cellular level
2.24	1.55e-22	GO:0007049	cell cycle
1.63	1.65e-22	GO:0010556	regulation of macromolecule biosynthetic process
1.87	2.10e-21	GO:0006996	organelle organization
1.50	1.60e-20	GO:0060255	regulation of macromolecule metabolic process
1.58	2.55e-20	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.63	2.86e-20	GO:0051252	regulation of RNA metabolic process
1.57	3.29e-20	GO:0051171	regulation of nitrogen compound metabolic process
1.74	8.86e-20	GO:0032774	RNA biosynthetic process
1.48	1.33e-19	GO:0031323	regulation of cellular metabolic process
1.74	1.36e-19	GO:0006351	transcription, DNA-dependent
2.52	3.31e-19	GO:0006259	DNA metabolic process
1.56	6.06e-19	GO:0031326	regulation of cellular biosynthetic process
1.55	6.61e-19	GO:0009889	regulation of biosynthetic process
1.43	7.83e-19	GO:0019222	regulation of metabolic process
1.61	1.72e-18	GO:0006355	regulation of transcription, DNA-dependent
1.47	2.26e-18	GO:0080090	regulation of primary metabolic process
1.17	1.28e-17	GO:0009987	cellular process
1.54	1.61e-17	GO:0019538	protein metabolic process
3.01	1.77e-17	GO:0008380	RNA splicing
2.54	4.91e-17	GO:0022403	cell cycle phase
1.62	5.00e-17	GO:0071842	cellular component organization at cellular level
2.72	5.39e-17	GO:0016071	mRNA metabolic process
1.50	9.88e-17	GO:0071840	cellular component organization or biogenesis
2.28	1.65e-16	GO:0022402	cell cycle process
2.79	6.32e-15	GO:0006281	DNA repair
1.65	6.88e-15	GO:0043412	macromolecule modification
2.31	9.95e-15	GO:0051276	chromosome organization
2.59	6.01e-14	GO:0051301	cell division
2.44	7.67e-14	GO:0006974	response to DNA damage stimulus
2.44	3.36e-13	GO:0000278	mitotic cell cycle
2.53	4.39e-13	GO:0000279	M phase
2.69	5.82e-13	GO:0006412	translation
1.61	3.42e-12	GO:0006464	protein modification process
1.44	4.41e-12	GO:0016043	cellular component organization
2.62	4.72e-12	GO:0006397	mRNA processing
2.72	1.18e-10	GO:0034660	ncRNA metabolic process
2.71	2.11e-10	GO:0000087	M phase of mitotic cell cycle
2.84	4.30e-10	GO:0071843	cellular component biogenesis at cellular level
1.94	4.41e-10	GO:0033554	cellular response to stress
2.69	8.41e-10	GO:0000280	nuclear division
2.69	8.41e-10	GO:0007067	mitosis
2.83	1.97e-09	GO:0022613	ribonucleoprotein complex biogenesis
2.33	2.55e-09	GO:0016568	chromatin modification
2.14	3.91e-09	GO:0044265	cellular macromolecule catabolic process
2.58	5.73e-09	GO:0048285	organelle fission
2.19	1.17e-08	GO:0006325	chromatin organization
2.77	1.30e-08	GO:0034470	ncRNA processing
1.68	2.10e-08	GO:0008104	protein localization
1.68	4.52e-08	GO:0010605	negative regulation of macromolecule metabolic process
1.67	4.57e-08	GO:0051641	cellular localization
3.09	5.42e-08	GO:0042254	ribosome biogenesis
1.99	6.22e-08	GO:0009057	macromolecule catabolic process
1.66	9.80e-08	GO:0044085	cellular component biogenesis
1.85	2.39e-07	GO:0046907	intracellular transport
1.58	3.94e-07	GO:0033036	macromolecule localization
1.60	1.11e-06	GO:0009892	negative regulation of metabolic process
3.32	1.12e-06	GO:0006364	rRNA processing
1.68	1.21e-06	GO:0051649	establishment of localization in cell
2.77	2.49e-06	GO:0051169	nuclear transport
3.22	2.80e-06	GO:0016072	rRNA metabolic process
2.28	4.27e-06	GO:0010608	posttranscriptional regulation of gene expression
2.76	4.45e-06	GO:0006913	nucleocytoplasmic transport
2.48	5.75e-06	GO:0016570	histone modification
3.38	8.89e-06	GO:0006403	RNA localization
2.44	1.01e-05	GO:0016569	covalent chromatin modification
2.32	1.39e-05	GO:0010564	regulation of cell cycle process
1.58	1.47e-05	GO:0031324	negative regulation of cellular metabolic process
3.38	1.62e-05	GO:0050657	nucleic acid transport
3.38	1.62e-05	GO:0050658	RNA transport
3.38	1.62e-05	GO:0051236	establishment of RNA localization
4.20	2.14e-05	GO:0006368	transcription elongation from RNA polymerase II promoter
2.47	2.99e-05	GO:0006730	one-carbon metabolic process
1.49	3.10e-05	GO:0010604	positive regulation of macromolecule metabolic process
1.63	3.71e-05	GO:0045184	establishment of protein localization
1.59	4.25e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
1.48	4.80e-05	GO:0031325	positive regulation of cellular metabolic process
1.69	4.85e-05	GO:0010629	negative regulation of gene expression
3.08	5.37e-05	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
1.63	5.84e-05	GO:0015031	protein transport
2.78	5.84e-05	GO:0032259	methylation
2.93	6.17e-05	GO:0071156	regulation of cell cycle arrest
3.82	6.70e-05	GO:0006402	mRNA catabolic process
1.67	7.18e-05	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.83	7.91e-05	GO:0051726	regulation of cell cycle
3.94	7.95e-05	GO:0006354	transcription elongation, DNA-dependent
1.59	8.78e-05	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.88	1.02e-04	GO:0007059	chromosome segregation
1.65	1.05e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
1.57	1.21e-04	GO:0010557	positive regulation of macromolecule biosynthetic process
1.62	1.21e-04	GO:0051254	positive regulation of RNA metabolic process
3.47	1.28e-04	GO:0006302	double-strand break repair
1.66	1.29e-04	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.36	1.35e-04	GO:0051028	mRNA transport
2.87	1.85e-04	GO:0018205	peptidyl-lysine modification
2.87	1.85e-04	GO:0043414	macromolecule methylation
1.44	2.05e-04	GO:0009893	positive regulation of metabolic process
4.04	2.47e-04	GO:0000956	nuclear-transcribed mRNA catabolic process
1.98	2.52e-04	GO:0070647	protein modification by small protein conjugation or removal
1.64	2.94e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
2.50	4.56e-04	GO:0006417	regulation of translation
2.01	5.12e-04	GO:0018193	peptidyl-amino acid modification
1.59	5.41e-04	GO:0045893	positive regulation of transcription, DNA-dependent
3.22	6.26e-04	GO:0006401	RNA catabolic process
1.59	6.43e-04	GO:0031327	negative regulation of cellular biosynthetic process
1.52	6.48e-04	GO:0031328	positive regulation of cellular biosynthetic process
1.77	6.94e-04	GO:0070727	cellular macromolecule localization
1.56	6.95e-04	GO:0010628	positive regulation of gene expression
1.58	7.30e-04	GO:0009890	negative regulation of biosynthetic process
2.86	8.52e-04	GO:0000075	cell cycle checkpoint
1.65	8.95e-04	GO:0051253	negative regulation of RNA metabolic process
3.60	9.84e-04	GO:0051168	nuclear export
1.76	1.04e-03	GO:0034613	cellular protein localization
1.50	1.10e-03	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.50	1.25e-03	GO:0009891	positive regulation of biosynthetic process
2.49	1.65e-03	GO:0006366	transcription from RNA polymerase II promoter
1.62	2.68e-03	GO:0045892	negative regulation of transcription, DNA-dependent
8.45	2.72e-03	GO:0006303	double-strand break repair via nonhomologous end joining
4.02	3.19e-03	GO:0000819	sister chromatid segregation
2.59	3.20e-03	GO:0006399	tRNA metabolic process
1.31	3.56e-03	GO:0048523	negative regulation of cellular process
2.73	3.96e-03	GO:0043543	protein acylation
1.63	4.41e-03	GO:0071844	cellular component assembly at cellular level
7.02	4.78e-03	GO:0000726	non-recombinational repair
4.09	5.63e-03	GO:0000070	mitotic sister chromatid segregation
2.26	6.53e-03	GO:0006260	DNA replication
2.85	7.14e-03	GO:0006473	protein acetylation
2.98	8.54e-03	GO:0006352	transcription initiation, DNA-dependent
2.53	1.22e-02	GO:0006310	DNA recombination
1.89	1.31e-02	GO:0006511	ubiquitin-dependent protein catabolic process
1.82	1.31e-02	GO:0030163	protein catabolic process
1.87	1.48e-02	GO:0043632	modification-dependent macromolecule catabolic process
1.27	1.74e-02	GO:0048519	negative regulation of biological process
1.26	1.83e-02	GO:0048522	positive regulation of cellular process
2.86	1.83e-02	GO:0006475	internal protein amino acid acetylation
2.86	1.83e-02	GO:0018393	internal peptidyl-lysine acetylation
2.22	1.86e-02	GO:0031396	regulation of protein ubiquitination
2.08	2.09e-02	GO:0007346	regulation of mitotic cell cycle
1.89	2.27e-02	GO:0032446	protein modification by small protein conjugation
2.82	2.34e-02	GO:0006479	protein methylation
2.82	2.34e-02	GO:0008213	protein alkylation
2.82	2.34e-02	GO:0018394	peptidyl-lysine acetylation
3.92	2.34e-02	GO:0006405	RNA export from nucleus
2.60	2.43e-02	GO:0006414	translational elongation
1.83	2.54e-02	GO:0044257	cellular protein catabolic process
1.85	2.55e-02	GO:0019941	modification-dependent protein catabolic process
1.83	3.15e-02	GO:0051603	proteolysis involved in cellular protein catabolic process
1.24	3.31e-02	GO:0048518	positive regulation of biological process
6.76	3.38e-02	GO:0071044	histone mRNA catabolic process
1.45	3.70e-02	GO:0022607	cellular component assembly
2.80	4.23e-02	GO:0016573	histone acetylation

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.43	6.36e-102	GO:0005622	intracellular
1.87	7.41e-102	GO:0005634	nucleus
1.57	3.11e-99	GO:0043231	intracellular membrane-bounded organelle
1.43	5.40e-99	GO:0044424	intracellular part
1.56	6.45e-99	GO:0043227	membrane-bounded organelle
1.51	1.06e-97	GO:0043229	intracellular organelle
1.50	5.19e-97	GO:0043226	organelle
2.30	9.78e-61	GO:0044428	nuclear part
1.75	4.41e-59	GO:0044446	intracellular organelle part
1.73	4.57e-58	GO:0044422	organelle part
2.18	4.21e-49	GO:0031974	membrane-enclosed lumen
2.30	9.60e-49	GO:0031981	nuclear lumen
2.19	2.13e-48	GO:0070013	intracellular organelle lumen
2.19	3.43e-48	GO:0043233	organelle lumen
1.72	4.75e-42	GO:0032991	macromolecular complex
2.37	6.78e-36	GO:0005654	nucleoplasm
1.32	1.03e-29	GO:0005737	cytoplasm
1.63	2.80e-26	GO:0043234	protein complex
1.67	1.74e-24	GO:0043228	non-membrane-bounded organelle
1.67	1.74e-24	GO:0043232	intracellular non-membrane-bounded organelle
1.13	5.73e-22	GO:0005623	cell
1.13	5.73e-22	GO:0044464	cell part
2.59	2.32e-21	GO:0030529	ribonucleoprotein complex
2.30	3.60e-21	GO:0044451	nucleoplasm part
2.46	2.43e-17	GO:0005694	chromosome
2.45	9.98e-16	GO:0044427	chromosomal part
2.35	4.58e-12	GO:0005730	nucleolus
1.27	1.99e-11	GO:0044444	cytoplasmic part
1.59	1.06e-10	GO:0005829	cytosol
2.53	2.96e-08	GO:0000785	chromatin
2.93	6.15e-08	GO:0000775	chromosome, centromeric region
2.61	9.36e-08	GO:0044454	nuclear chromosome part
2.47	1.62e-07	GO:0000228	nuclear chromosome
3.83	5.23e-07	GO:0000792	heterochromatin
2.99	7.67e-07	GO:0005819	spindle
2.57	9.10e-07	GO:0005840	ribosome
2.99	1.16e-05	GO:0000790	nuclear chromatin
3.41	1.70e-05	GO:0016591	DNA-directed RNA polymerase II, holoenzyme
2.59	2.90e-05	GO:0005681	spliceosomal complex
1.71	3.69e-05	GO:0015630	microtubule cytoskeleton
3.44	1.03e-04	GO:0034708	methyltransferase complex
3.44	1.03e-04	GO:0035097	histone methyltransferase complex
4.00	1.16e-04	GO:0000922	spindle pole
1.40	1.19e-04	GO:0005739	mitochondrion
3.02	1.35e-04	GO:0071013	catalytic step 2 spliceosome
2.43	2.44e-04	GO:0016604	nuclear body
4.14	3.58e-04	GO:0015934	large ribosomal subunit
3.17	4.90e-04	GO:0000123	histone acetyltransferase complex
2.81	6.17e-04	GO:0000776	kinetochore
1.84	1.85e-03	GO:0005667	transcription factor complex
4.83	1.41e-02	GO:0000428	DNA-directed RNA polymerase complex
4.83	1.41e-02	GO:0055029	nuclear DNA-directed RNA polymerase complex
1.97	1.68e-02	GO:0005635	nuclear envelope
1.93	1.76e-02	GO:0005813	centrosome
1.44	1.97e-02	GO:0012505	endomembrane system
4.57	2.43e-02	GO:0030880	RNA polymerase complex
2.50	2.88e-02	GO:0016585	chromatin remodeling complex
5.63	3.22e-02	GO:0005665	DNA-directed RNA polymerase II, core complex
8.04	3.34e-02	GO:0070419	nonhomologous end joining complex
3.30	3.50e-02	GO:0005720	nuclear heterochromatin
4.02	3.57e-02	GO:0044452	nucleolar part
1.83	3.92e-02	GO:0005815	microtubule organizing center
3.07	4.59e-02	GO:0005643	nuclear pore

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.93	3.93e-50	GO:0003676	nucleic acid binding
2.56	2.44e-31	GO:0003723	RNA binding
1.24	6.88e-31	GO:0005488	binding
1.68	6.88e-22	GO:0000166	nucleotide binding
1.75	1.23e-21	GO:0003677	DNA binding
1.30	3.85e-13	GO:0003824	catalytic activity
1.27	1.34e-11	GO:0005515	protein binding
1.55	2.82e-11	GO:0035639	purine ribonucleoside triphosphate binding
1.54	5.54e-11	GO:0017076	purine nucleotide binding
1.54	5.90e-11	GO:0032555	purine ribonucleotide binding
1.53	6.33e-11	GO:0032553	ribonucleotide binding
1.57	1.32e-09	GO:0005524	ATP binding
1.56	1.41e-09	GO:0030554	adenyl nucleotide binding
1.56	1.49e-09	GO:0032559	adenyl ribonucleotide binding
1.68	3.77e-08	GO:0030528	transcription regulator activity
1.45	2.28e-07	GO:0016740	transferase activity
2.00	4.62e-07	GO:0016874	ligase activity
1.50	1.32e-06	GO:0008270	zinc ion binding
1.59	3.62e-06	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.97	5.63e-05	GO:0016564	transcription repressor activity
2.24	6.62e-05	GO:0003682	chromatin binding
1.55	1.40e-04	GO:0019899	enzyme binding
1.38	1.93e-04	GO:0046914	transition metal ion binding
1.91	4.03e-04	GO:0008134	transcription factor binding
2.67	4.14e-04	GO:0016779	nucleotidyltransferase activity
1.97	1.22e-03	GO:0016879	ligase activity, forming carbon-nitrogen bonds
2.04	4.03e-03	GO:0043566	structure-specific DNA binding
2.39	4.48e-03	GO:0003735	structural constituent of ribosome
2.30	5.14e-03	GO:0004386	helicase activity
2.17	5.85e-03	GO:0008168	methyltransferase activity
1.53	6.69e-03	GO:0016462	pyrophosphatase activity
1.53	8.19e-03	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.52	8.76e-03	GO:0016817	hydrolase activity, acting on acid anhydrides
3.10	1.04e-02	GO:0008276	protein methyltransferase activity
2.11	1.05e-02	GO:0016741	transferase activity, transferring one-carbon groups
2.49	1.34e-02	GO:0008135	translation factor activity, nucleic acid binding
1.51	2.07e-02	GO:0017111	nucleoside-triphosphatase activity
1.45	2.80e-02	GO:0001071	nucleic acid binding transcription factor activity
1.45	2.80e-02	GO:0003700	sequence-specific DNA binding transcription factor activity
1.84	2.87e-02	GO:0003712	transcription cofactor activity
1.81	3.15e-02	GO:0019901	protein kinase binding
1.83	3.20e-02	GO:0000989	transcription factor binding transcription factor activity
1.86	3.21e-02	GO:0016881	acid-amino acid ligase activity
3.62	3.33e-02	GO:0034061	DNA polymerase activity
1.54	3.48e-02	GO:0019904	protein domain specific binding
2.57	3.92e-02	GO:0042393	histone binding
1.81	4.38e-02	GO:0000988	protein binding transcription factor activity
1.77	4.64e-02	GO:0016887	ATPase activity
8.04	4.71e-02	GO:0008327	methyl-CpG binding