Motif ID: ONECUT1,2.p2

Z-value: 1.151


Transcription factors associated with ONECUT1,2.p2:

Gene SymbolEntrez IDGene Name
Onecut1 15379 one cut domain, family member 1
Onecut2 225631 one cut domain, family member 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Onecut1chr9_+_747096730.298.8e-05Click!
Onecut2chr18_+_645000170.198.5e-03Click!


Activity profile for motif ONECUT1,2.p2.

activity profile for motif ONECUT1,2.p2


Sorted Z-values histogram for motif ONECUT1,2.p2

Sorted Z-values for motif ONECUT1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ONECUT1,2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_60963495 29.938 NM_001042605
NM_010545
 Cd74

CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

chr17_-_32557807 21.802 Pglyrp2
peptidoglycan recognition protein 2
chr17_-_32557916 21.459 NM_021319
 Pglyrp2
peptidoglycan recognition protein 2
chr9_-_113563906 20.770 Pdcd6ip
programmed cell death 6 interacting protein
chr17_-_45724536 17.511 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr1_-_140071818 17.241 NM_001111316
NM_011210
 Ptprc

protein tyrosine phosphatase, receptor type, C

chr1_+_89999782 15.996 NM_201410
 Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr17_+_35404109 15.756


chr6_-_128476708 14.124 NM_007376
 Pzp
pregnancy zone protein
chr17_-_57354126 13.219 C3
complement component 3
chr3_+_19869841 12.334 Cp
ceruloplasmin
chr3_-_10208575 12.011 NM_024406
 Fabp4
fatty acid binding protein 4, adipocyte
chr17_+_35403998 11.726


chr5_+_104868321 11.467 Spp1
secreted phosphoprotein 1
chr2_-_91035226 11.172 NM_001177730
 Nr1h3
nuclear receptor subfamily 1, group H, member 3
chr3_+_60432922 11.014 Mbnl1
muscleblind-like 1 (Drosophila)
chr5_-_17355533 10.920 NM_001159556
NM_001159557
 Cd36

CD36 antigen

chr12_-_105195097 10.655 NM_009247
 Serpina1e
serine (or cysteine) peptidase inhibitor, clade A, member 1E
chr1_+_90031368 10.457 NM_145079
 Ugt1a6a
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr17_-_34999068 10.299 Cfb
complement factor B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 22 entries
Enrichment   P-value GO Accession GO Term
5.98 8.86e-03 GO:0031214 biomineral tissue development
2.88 6.69e-03 GO:0052547 regulation of peptidase activity
2.86 1.91e-02 GO:0052548 regulation of endopeptidase activity
2.69 4.96e-02 GO:0034097 response to cytokine stimulus
2.48 9.93e-03 GO:0032787 monocarboxylic acid metabolic process
2.10 1.09e-02 GO:0044092 negative regulation of molecular function
1.95 2.70e-02 GO:0019752 carboxylic acid metabolic process
1.95 2.70e-02 GO:0043436 oxoacid metabolic process
1.94 2.28e-02 GO:0006082 organic acid metabolic process
1.92 4.99e-03 GO:0055114 oxidation-reduction process
1.84 1.70e-03 GO:0042981 regulation of apoptosis
1.82 2.58e-03 GO:0043067 regulation of programmed cell death
1.80 3.25e-03 GO:0010941 regulation of cell death
1.53 6.35e-04 GO:0048519 negative regulation of biological process
1.50 6.84e-03 GO:0048523 negative regulation of cellular process
1.44 3.94e-03 GO:0048518 positive regulation of biological process
1.36 3.60e-02 GO:0009058 biosynthetic process
1.34 3.14e-02 GO:0080090 regulation of primary metabolic process
1.29 2.49e-06 GO:0008152 metabolic process
1.29 1.43e-04 GO:0044237 cellular metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
Enrichment   P-value GO Accession GO Term
6.76 1.66e-02 GO:0005581 collagen
3.05 7.94e-03 GO:0005938 cell cortex
2.30 2.34e-02 GO:0005578 proteinaceous extracellular matrix
1.68 1.36e-02 GO:0044421 extracellular region part
1.41 2.43e-03 GO:0043234 protein complex
1.40 4.10e-04 GO:0032991 macromolecular complex
1.30 8.57e-05 GO:0044444 cytoplasmic part
1.28 1.86e-03 GO:0005634 nucleus
1.24 8.71e-06 GO:0043227 membrane-bounded organelle
1.24 1.00e-05 GO:0043231 intracellular membrane-bounded organelle
1.24 2.32e-05 GO:0005737 cytoplasm
1.22 1.03e-05 GO:0043226 organelle
1.21 2.26e-05 GO:0043229 intracellular organelle
1.20 2.90e-07 GO:0005622 intracellular
1.20 3.91e-07 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
Enrichment   P-value GO Accession GO Term
7.79 5.18e-04 GO:0005201 extracellular matrix structural constituent
5.28 4.54e-02 GO:0050661 NADP binding
3.70 3.74e-04 GO:0004497 monooxygenase activity
3.35 3.15e-02 GO:0004867 serine-type endopeptidase inhibitor activity
3.14 4.47e-03 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
3.04 4.20e-03 GO:0061135 endopeptidase regulator activity
3.00 8.54e-03 GO:0004866 endopeptidase inhibitor activity
2.84 1.85e-02 GO:0030414 peptidase inhibitor activity
2.15 1.92e-02 GO:0030246 carbohydrate binding
2.01 3.35e-04 GO:0016491 oxidoreductase activity
1.35 1.36e-06 GO:0005515 protein binding
1.22 1.24e-08 GO:0005488 binding