• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: ONECUT1,2.p2

Z-value: 1.151

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr18_+_60963495	29.938	NM_001042605 NM_010545	Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
chr17_-_32557807	21.802		Pglyrp2	peptidoglycan recognition protein 2
chr17_-_32557916	21.459	NM_021319	Pglyrp2	peptidoglycan recognition protein 2
chr9_-_113563906	20.770		Pdcd6ip	programmed cell death 6 interacting protein
chr17_-_45724536	17.511		Slc29a1	solute carrier family 29 (nucleoside transporters), member 1
chr1_-_140071818	17.241	NM_001111316 NM_011210	Ptprc	protein tyrosine phosphatase, receptor type, C
chr1_+_89999782	15.996	NM_201410	Ugt1a6b	UDP glucuronosyltransferase 1 family, polypeptide A6B
chr17_+_35404109	15.756
chr6_-_128476708	14.124	NM_007376	Pzp	pregnancy zone protein
chr17_-_57354126	13.219		C3	complement component 3
chr3_+_19869841	12.334		Cp	ceruloplasmin
chr3_-_10208575	12.011	NM_024406	Fabp4	fatty acid binding protein 4, adipocyte
chr17_+_35403998	11.726
chr5_+_104868321	11.467		Spp1	secreted phosphoprotein 1
chr2_-_91035226	11.172	NM_001177730	Nr1h3	nuclear receptor subfamily 1, group H, member 3
chr3_+_60432922	11.014		Mbnl1	muscleblind-like 1 (Drosophila)
chr5_-_17355533	10.920	NM_001159556 NM_001159557	Cd36	CD36 antigen
chr12_-_105195097	10.655	NM_009247	Serpina1e	serine (or cysteine) peptidase inhibitor, clade A, member 1E
chr1_+_90031368	10.457	NM_145079	Ugt1a6a	UDP glucuronosyltransferase 1 family, polypeptide A6A
chr17_-_34999068	10.299		Cfb	complement factor B
chr3_+_19857053	9.936	NM_001042611 NM_007752	Cp	ceruloplasmin
chr11_+_98913612	9.872
chr6_+_115372083	9.853	NM_011146	Pparg	peroxisome proliferator activated receptor gamma
chr17_-_34134101	9.478		H2-K1	histocompatibility 2, K1, K region
chr3_-_15426426	9.294	NM_001002898	Sirpb1a	signal-regulatory protein beta 1A
chr13_-_56280161	9.161	NM_001168615 NM_145976	Tifab	TRAF-interacting protein with forkhead-associated domain, family member B
chr3_-_15748418	9.051	NM_001173459	LOC100038947 Sirpb1a	signal-regulatory protein beta 1-like signal-regulatory protein beta 1A
chr1_-_140071630	8.563		Ptprc	protein tyrosine phosphatase, receptor type, C
chr9_+_65738150	8.453		2810417H13Rik	RIKEN cDNA 2810417H13 gene
chr3_-_57105840	8.020	NM_008536	Tm4sf1	transmembrane 4 superfamily member 1
chr17_-_34999458	7.962	NM_001142706 NM_008198	Cfb	complement factor B
chr12_+_82049290	7.941		Srsf5	serine/arginine-rich splicing factor 5
chr9_+_108239210	7.914		Rhoa	ras homolog gene family, member A
chr3_+_19857375	7.885		Cp	ceruloplasmin
chr17_+_35403130	7.851		H2-D1	histocompatibility 2, D region locus 1
chr2_-_84281089	7.673		Tfpi	tissue factor pathway inhibitor
chr12_-_71328615	7.600		Pygl	liver glycogen phosphorylase
chr12_-_104976382	7.550	NM_009244	Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B
chr12_-_71328622	7.478	NM_133198	Pygl	liver glycogen phosphorylase
chr12_-_104976324	7.402		Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B
chr1_+_45368443	7.281		Col3a1	collagen, type III, alpha 1
chr1_-_175842977	7.272	NM_001033450	Ifi204 Mnda	interferon activated gene 204 myeloid cell nuclear differentiation antigen
chr4_+_109015660	7.255	NM_001159964	Eps15	epidermal growth factor receptor pathway substrate 15
chr9_+_89094110	7.128	NM_007534	Bcl2a1a Bcl2a1b	B-cell leukemia/lymphoma 2 related protein A1a B-cell leukemia/lymphoma 2 related protein A1b
chr12_-_71328603	6.966		Pygl	liver glycogen phosphorylase
chr13_+_95335701	6.731
chr9_+_89094190	6.617		Bcl2a1a	B-cell leukemia/lymphoma 2 related protein A1a
chr3_-_81779636	6.613	NM_019911	Tdo2	tryptophan 2,3-dioxygenase
chr3_+_135128934	6.487		Ube2d3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr12_-_105101825	6.420	NM_009243	Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A
chr2_+_122310676	6.373	NM_001085518	Gm14085	predicted gene 14085
chr5_+_90893032	6.331		Alb	albumin
chr3_+_28596824	6.174	NM_031197	Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2
chr12_-_105101768	6.159		Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A
chr12_-_105101743	6.109		Serpina1a Serpina1b Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1A serine (or cysteine) preptidase inhibitor, clade A, member 1B serine (or cysteine) peptidase inhibitor, clade A, member 1C
chr3_-_10208480	6.032		Fabp4 Fabp9	fatty acid binding protein 4, adipocyte fatty acid binding protein 9, testis
chr12_-_105066203	5.890		Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B
chr19_+_12535536	5.818		Mpeg1	macrophage expressed gene 1
chr1_+_58859345	5.738	NM_001080126	Casp8	caspase 8
chr10_+_126503214	5.636		Cdk4	cyclin-dependent kinase 4
chr1_-_64167574	5.575		Klf7	Kruppel-like factor 7 (ubiquitous)
chr10_+_128227964	5.531	NM_001164197 NM_021412	Mmp19	matrix metallopeptidase 19
chr12_-_105143089	5.515		Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C
chr7_-_113102453	5.468	NM_001039160 NM_029000	Gvin1	GTPase, very large interferon inducible 1
chr7_-_113358823	5.468	NM_001039160 NM_029000	Gvin1	GTPase, very large interferon inducible 1
chr9_+_21142267	5.407	NM_152808	Slc44a2	solute carrier family 44, member 2
chr17_-_44951745	5.376	NM_001146038 NM_009820	Runx2	runt related transcription factor 2
chr6_+_48634576	5.299	NM_174990 NM_175048	Gimap4	GTPase, IMAP family member 4
chr10_-_36855292	5.284		Marcks	myristoylated alanine rich protein kinase C substrate
chr9_+_65738168	5.245		2810417H13Rik	RIKEN cDNA 2810417H13 gene
chr1_-_182186429	5.191	NM_001128605	Psen2	presenilin 2
chr8_-_46347384	5.119	NM_028066	F11	coagulation factor XI
chr8_-_124948837	5.080
chr15_-_96861590	5.075		Slc38a4	solute carrier family 38, member 4
chr7_+_148645664	5.068		Pnpla2	patatin-like phospholipase domain containing 2
chr9_+_88851757	4.976	NM_009742	Bcl2a1a	B-cell leukemia/lymphoma 2 related protein A1a
chr2_-_163462584	4.971		Serinc3	serine incorporator 3
chr6_-_119305193	4.967		Adipor2	adiponectin receptor 2
chr8_-_46347363	4.965		F11	coagulation factor XI
chr1_-_64167952	4.954	NM_033563	Klf7	Kruppel-like factor 7 (ubiquitous)
chr14_+_71174110	4.932	NM_010071	Dok2	docking protein 2
chr2_-_10052196	4.893	NM_010582	Itih2	inter-alpha trypsin inhibitor, heavy chain 2
chrX_+_156411885	4.869		Sh3kbp1	SH3-domain kinase binding protein 1
chr8_+_74662546	4.841		Tpm4	tropomyosin 4
chr12_+_105625371	4.800	NM_009253	Serpina3m	serine (or cysteine) peptidase inhibitor, clade A, member 3M
chr1_-_173579128	4.753		Slamf7	SLAM family member 7
chr7_+_138712015	4.734		Bub3	budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae)
chr6_-_124586102	4.731	NM_173864	Gm5077	predicted gene 5077
chr19_+_12535268	4.726	NM_010821	Mpeg1	macrophage expressed gene 1
chr10_-_61960613	4.724		Srgn	serglycin
chr16_-_8672226	4.644		Carhsp1	calcium regulated heat stable protein 1
chr11_-_21222127	4.639		Ugp2	UDP-glucose pyrophosphorylase 2
chr12_-_105143108	4.613	NM_009245	Serpina1c	serine (or cysteine) peptidase inhibitor, clade A, member 1C
chr10_+_21097094	4.611	NM_178713	Aldh8a1	aldehyde dehydrogenase 8 family, member A1
chr10_+_82359714	4.539		Txnrd1	thioredoxin reductase 1
chr18_+_54113094	4.359		Csnk1g3	casein kinase 1, gamma 3
chr4_+_140258090	4.293		Rcc2	regulator of chromosome condensation 2
chr6_+_48634586	4.281		Gimap4	GTPase, IMAP family member 4
chr18_+_21119972	4.209		Rnf125	ring finger protein 125
chr12_-_105011767	4.188		Serpina1d	serine (or cysteine) peptidase inhibitor, clade A, member 1D
chr7_-_52068757	4.177		Atf5	activating transcription factor 5
chr11_+_82988687	4.159	NM_011410	Slfn4	schlafen 4
chr1_+_9788206	4.137	NM_133220 NM_177547	Sgk3	serum/glucocorticoid regulated kinase 3
chr16_+_17331507	4.136		Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1
chr17_-_46168654	4.132		Vegfa	vascular endothelial growth factor A
chr6_+_97941776	4.110	NM_008601	Mitf	microphthalmia-associated transcription factor
chr9_+_65738129	4.094	NM_026515	2810417H13Rik	RIKEN cDNA 2810417H13 gene
chr12_-_105011795	4.055		Serpina1d	serine (or cysteine) peptidase inhibitor, clade A, member 1D
chr7_+_126904427	4.035	NM_016870 NM_212441 NM_212442	Acsm3	acyl-CoA synthetase medium-chain family member 3
chr12_-_105011807	4.025	NM_009246	Serpina1d	serine (or cysteine) peptidase inhibitor, clade A, member 1D
chr15_-_66644127	4.023	NM_009192	Sla	src-like adaptor
chr1_-_175872522	4.012	NM_008328 NM_001045481	Ifi203	interferon activated gene 203
chr15_+_54943978	3.956	NM_145470	Deptor	DEP domain containing MTOR-interacting protein
chrX_+_12870471	3.954		Ddx3x	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
chr2_-_3283840	3.885	NM_145921	Olah	oleoyl-ACP hydrolase
chr17_-_34134309	3.767		H2-K1	histocompatibility 2, K1, K region
chr15_-_57702643	3.699		Derl1	Der1-like domain family, member 1
chr14_+_51748742	3.683	NM_030098	Rnase6	ribonuclease, RNase A family, 6
chr9_-_96379093	3.681		Rnf7	ring finger protein 7
chr17_+_57498108	3.668	NM_010130	Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1
chr8_+_47620401	3.659		Acsl1	acyl-CoA synthetase long-chain family member 1
chr16_+_17331463	3.628	NM_008223	Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1
chr15_-_99609024	3.623		Lima1	LIM domain and actin binding 1
chr1_-_174825067	3.609		Apcs	serum amyloid P-component
chr17_-_34941343	3.588	NM_009995	Cyp21a1	cytochrome P450, family 21, subfamily a, polypeptide 1
chr5_-_104058250	3.563	NM_029415	Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr1_-_64167818	3.555		Klf7	Kruppel-like factor 7 (ubiquitous)
chr7_+_147960463	3.526		Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1
chr9_-_43951401	3.495
chr14_+_18814157	3.492	NM_009380	Thrb	thyroid hormone receptor beta
chr4_+_140257340	3.479	NM_173867	Rcc2	regulator of chromosome condensation 2
chr2_-_25483295	3.456		Fcna	ficolin A
chr7_+_29225955	3.453	NM_001039192	Gmfg	glia maturation factor, gamma
chr16_-_8672242	3.450	NM_025821	Carhsp1	calcium regulated heat stable protein 1
chr2_-_147872704	3.445	NM_010446	Foxa2	forkhead box A2
chr7_-_80686630	3.439	NM_001081345	Chd2	chromodomain helicase DNA binding protein 2
chr3_+_89006824	3.435	NM_001077411 NM_008094	Gba	glucosidase, beta, acid
chr15_+_54943878	3.428		Deptor	DEP domain containing MTOR-interacting protein
chr17_-_43013320	3.421	NM_009847	Cd2ap	CD2-associated protein
chr2_+_40412520	3.367		Eef1a1	eukaryotic translation elongation factor 1 alpha 1
chr5_-_134705423	3.360	NM_010876	Ncf1	neutrophil cytosolic factor 1
chr2_-_25483461	3.313	NM_007995	Fcna	ficolin A
chr10_+_75052084	3.252	NM_011820	Ggt5	gamma-glutamyltransferase 5
chr8_+_34763709	3.220	NM_010344	Gsr	glutathione reductase
chr10_-_31134240	3.218	NM_011509	Gm3258	predicted gene 3258
chr6_+_141634834	3.178
chr7_+_147949637	3.160		Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1
chr1_+_70772288	3.156	NM_177164	Vwc2l	von Willebrand factor C domain-containing protein 2-like
chr13_-_13097596	3.152	NM_031191	Prl2c2	prolactin family 2, subfamily c, member 2
chr9_-_114299732	3.151	NM_019922	Crtap	cartilage associated protein
chr6_-_119338677	3.149		Adipor2	adiponectin receptor 2
chr10_-_127935725	3.091	NM_172259	Myl6b	myosin, light polypeptide 6B
chr6_+_54839147	3.087		Znrf2	zinc and ring finger 2
chrX_+_9829439	3.078	NM_008769	Otc	ornithine transcarbamylase
chr16_+_37580238	3.062	NM_013547	Hgd	homogentisate 1, 2-dioxygenase
chr12_+_110089325	3.037	NM_001012310	Slc25a47	solute carrier family 25, member 47
chr5_-_114292851	3.006		Coro1c	coronin, actin binding protein 1C
chr15_+_25901865	3.004		Fam134b	family with sequence similarity 134, member B
chr13_-_12892317	2.999	NM_011118 NM_011954	Prl2c3 Prl2c4	prolactin family 2, subfamily c, member 3 prolactin family 2, subfamily c, member 4
chr10_+_127452270	2.995	NM_008921	Prim1	DNA primase, p49 subunit
chr8_-_4779533	2.986	NM_011369	Shcbp1	Shc SH2-domain binding protein 1
chr17_+_24879324	2.941		Sepx1	selenoprotein X 1
chr5_-_143666064	2.935		Actb	actin, beta
chr19_-_40261753	2.927	NM_145499	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70
chr18_-_46887869	2.919	NM_033037	Cdo1	cysteine dioxygenase 1, cytosolic
chr10_-_61441817	2.912		Col13a1	collagen, type XIII, alpha 1
chr17_+_35189798	2.909
chr9_-_78326621	2.896		Eef1a1	eukaryotic translation elongation factor 1 alpha 1
chr9_-_62644026	2.887		Fem1b	feminization 1 homolog b (C. elegans)
chr7_+_35829312	2.872		Pepd	peptidase D
chr15_+_102289600	2.859	NM_001170911 NM_025385	Prr13	proline rich 13
chr4_-_108790523	2.849		Osbpl9	oxysterol binding protein-like 9
chrX_+_156278399	2.845	NM_001135728	Sh3kbp1	SH3-domain kinase binding protein 1
chr2_-_60590923	2.842		Rbms1	RNA binding motif, single stranded interacting protein 1
chr12_-_105094033	2.836		Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A
chr1_+_6720087	2.802	NM_173868	St18	suppression of tumorigenicity 18
chr5_-_52541869	2.802		Dhx15	DEAH (Asp-Glu-Ala-His) box polypeptide 15
chr1_+_6720153	2.773		St18	suppression of tumorigenicity 18
chr19_-_30623890	2.759	NM_010051	Dkk1	dickkopf homolog 1 (Xenopus laevis)
chr15_-_99609351	2.752		Lima1	LIM domain and actin binding 1
chr1_+_133534852	2.728	NM_007799	Ctse	cathepsin E
chr1_-_173579057	2.716		Slamf7	SLAM family member 7
chr10_+_127452219	2.715		Prim1	DNA primase, p49 subunit
chr2_-_58012447	2.712	NM_139200	Cytip	cytohesin 1 interacting protein
chr5_-_146821173	2.696	NM_019792	Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25
chr5_+_136559785	2.690	NM_001039103 NM_133914	Rasa4	RAS p21 protein activator 4
chr11_-_29501956	2.684
chr1_-_128727208	2.645	NM_001081756 NM_176957	Nckap5	NCK-associated protein 5
chr13_+_49639847	2.645		Aspn	asporin
chr3_-_148617598	2.617	NM_001081298	Lphn2	latrophilin 2
chr19_-_5918992	2.613	NM_026772	Cdc42ep2	CDC42 effector protein (Rho GTPase binding) 2
chr10_-_88875526	2.606		Gas2l3	growth arrest-specific 2 like 3
chr19_-_8206403	2.600	NM_001013820	Gm5631	predicted gene 5631
chr4_-_19447698	2.590		Cpne3	copine III
chr19_+_40066913	2.578	NM_010001	Cyp2c37	cytochrome P450, family 2. subfamily c, polypeptide 37
chr13_-_13097649	2.563		Prl2c2	prolactin family 2, subfamily c, member 2
chr16_-_36666078	2.562	NM_019388	Cd86	CD86 antigen
chr13_+_3564316	2.560		Gdi2	guanosine diphosphate (GDP) dissociation inhibitor 2
chr8_-_88063071	2.542
chr14_-_56407622	2.533	NM_001164107 NM_001164108 NM_019955	Ripk3	receptor-interacting serine-threonine kinase 3

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.29	2.49e-06	GO:0008152	metabolic process
1.29	1.43e-04	GO:0044237	cellular metabolic process
1.27	3.76e-04	GO:0044238	primary metabolic process
1.53	6.35e-04	GO:0048519	negative regulation of biological process
1.84	1.70e-03	GO:0042981	regulation of apoptosis
1.82	2.58e-03	GO:0043067	regulation of programmed cell death
1.80	3.25e-03	GO:0010941	regulation of cell death
1.44	3.94e-03	GO:0048518	positive regulation of biological process
1.92	4.99e-03	GO:0055114	oxidation-reduction process
2.88	6.69e-03	GO:0052547	regulation of peptidase activity
1.50	6.84e-03	GO:0048523	negative regulation of cellular process
5.98	8.86e-03	GO:0031214	biomineral tissue development
2.48	9.93e-03	GO:0032787	monocarboxylic acid metabolic process
2.10	1.09e-02	GO:0044092	negative regulation of molecular function
1.27	1.40e-02	GO:0043170	macromolecule metabolic process
2.86	1.91e-02	GO:0052548	regulation of endopeptidase activity
1.94	2.28e-02	GO:0006082	organic acid metabolic process
1.95	2.70e-02	GO:0019752	carboxylic acid metabolic process
1.95	2.70e-02	GO:0043436	oxoacid metabolic process
1.34	3.14e-02	GO:0080090	regulation of primary metabolic process
1.36	3.60e-02	GO:0009058	biosynthetic process
2.69	4.96e-02	GO:0034097	response to cytokine stimulus

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.20	2.90e-07	GO:0005622	intracellular
1.20	3.91e-07	GO:0044424	intracellular part
1.24	8.71e-06	GO:0043227	membrane-bounded organelle
1.24	1.00e-05	GO:0043231	intracellular membrane-bounded organelle
1.22	1.03e-05	GO:0043226	organelle
1.21	2.26e-05	GO:0043229	intracellular organelle
1.24	2.32e-05	GO:0005737	cytoplasm
1.30	8.57e-05	GO:0044444	cytoplasmic part
1.40	4.10e-04	GO:0032991	macromolecular complex
1.28	1.86e-03	GO:0005634	nucleus
1.41	2.43e-03	GO:0043234	protein complex
3.05	7.94e-03	GO:0005938	cell cortex
1.68	1.36e-02	GO:0044421	extracellular region part
6.76	1.66e-02	GO:0005581	collagen
2.30	2.34e-02	GO:0005578	proteinaceous extracellular matrix

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.22	1.24e-08	GO:0005488	binding
1.35	1.36e-06	GO:0005515	protein binding
2.01	3.35e-04	GO:0016491	oxidoreductase activity
3.70	3.74e-04	GO:0004497	monooxygenase activity
7.79	5.18e-04	GO:0005201	extracellular matrix structural constituent
3.04	4.20e-03	GO:0061135	endopeptidase regulator activity
3.14	4.47e-03	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
3.00	8.54e-03	GO:0004866	endopeptidase inhibitor activity
2.84	1.85e-02	GO:0030414	peptidase inhibitor activity
2.15	1.92e-02	GO:0030246	carbohydrate binding
3.35	3.15e-02	GO:0004867	serine-type endopeptidase inhibitor activity
5.28	4.54e-02	GO:0050661	NADP binding