Motif ID: PAX2.p2

Z-value: 1.322


Transcription factors associated with PAX2.p2:

Gene SymbolEntrez IDGene Name
Pax2 18504 paired box gene 2



Activity profile for motif PAX2.p2.

activity profile for motif PAX2.p2


Sorted Z-values histogram for motif PAX2.p2

Sorted Z-values for motif PAX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_83936038 18.620 Sult4a1
sulfotransferase family 4A, member 1
chr4_-_151851624 14.091 Kcnab2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr4_-_151851574 13.307 NM_010598
 Kcnab2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr11_+_69154265 12.847 A030009H04Rik
RIKEN cDNA A030009H04 gene
chr5_-_108978950 11.892 NM_007756
 Cplx1
complexin 1
chr11_+_78136681 11.867 Aldoc
aldolase C, fructose-bisphosphate
chr16_-_44139087 10.939 NM_007508
 Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
chr11_+_78136690 10.896 Aldoc
aldolase C, fructose-bisphosphate
chrX_-_132602648 10.778 NM_009749
 Bex2
brain expressed X-linked 2
chrX_-_20498021 10.436 NM_001110780
NM_013680
 Syn1

synapsin I

chr7_-_28338127 8.816 NM_011116
 Pld3
phospholipase D family, member 3
chr9_-_64101429 8.417 Map2k1
mitogen-activated protein kinase kinase 1
chr4_-_147412872 8.253 NM_011929
 Clcn6
chloride channel 6
chr6_+_116158049 8.218 NM_026585
 D6Wsu116e
DNA segment, Chr 6, Wayne State University 116, expressed
chr12_+_88288287 7.684 NM_173735
 2310044G17Rik
RIKEN cDNA 2310044G17 gene
chr10_+_110601745 7.680 NM_001003717
NM_175489
 Osbpl8

oxysterol binding protein-like 8

chr15_-_83936183 7.501 NM_013873
 Sult4a1
sulfotransferase family 4A, member 1
chr9_-_64101138 7.412 Map2k1
mitogen-activated protein kinase kinase 1
chr5_-_124022937 7.323 NM_029929
 Vps33a
vacuolar protein sorting 33A (yeast)
chrX_+_149574498 7.291 NM_001004154
 Rragb
Ras-related GTP binding B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 59 entries
Enrichment   P-value GO Accession GO Term
4.78 4.77e-03 GO:0015988 energy coupled proton transport, against electrochemical gradient
4.78 4.77e-03 GO:0015991 ATP hydrolysis coupled proton transport
4.60 7.83e-03 GO:0007040 lysosome organization
4.14 2.96e-02 GO:0015682 ferric iron transport
4.14 2.96e-02 GO:0033572 transferrin transport
4.00 7.86e-04 GO:0007269 neurotransmitter secretion
3.61 1.75e-02 GO:0048168 regulation of neuronal synaptic plasticity
3.60 9.03e-03 GO:0007033 vacuole organization
3.13 1.21e-03 GO:0001505 regulation of neurotransmitter levels
2.96 7.81e-04 GO:0006836 neurotransmitter transport
2.17 1.05e-04 GO:0007268 synaptic transmission
2.13 5.52e-06 GO:0019226 transmission of nerve impulse
2.13 5.52e-06 GO:0035637 multicellular organismal signaling
2.11 2.41e-03 GO:0006091 generation of precursor metabolites and energy
2.05 4.10e-02 GO:0050804 regulation of synaptic transmission
1.98 2.92e-02 GO:0031644 regulation of neurological system process
1.93 3.42e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.88 1.11e-09 GO:0015031 protein transport
1.86 1.36e-09 GO:0045184 establishment of protein localization
1.86 7.45e-03 GO:0006886 intracellular protein transport

Gene overrepresentation in compartment category:

Showing 1 to 20 of 51 entries
Enrichment   P-value GO Accession GO Term
5.45 1.32e-03 GO:0033176 proton-transporting V-type ATPase complex
4.28 3.24e-03 GO:0030672 synaptic vesicle membrane
3.83 2.72e-05 GO:0030665 clathrin coated vesicle membrane
3.36 2.84e-02 GO:0042734 presynaptic membrane
3.10 7.47e-04 GO:0030662 coated vesicle membrane
2.98 1.58e-03 GO:0044437 vacuolar part
2.89 7.26e-03 GO:0005774 vacuolar membrane
2.72 7.74e-04 GO:0008021 synaptic vesicle
2.65 2.94e-12 GO:0005773 vacuole
2.62 9.25e-10 GO:0000323 lytic vacuole
2.62 9.25e-10 GO:0005764 lysosome
2.51 2.41e-04 GO:0019717 synaptosome
2.48 1.51e-04 GO:0030136 clathrin-coated vesicle
2.43 1.11e-03 GO:0033267 axon part
2.42 1.12e-02 GO:0010008 endosome membrane
2.42 1.12e-02 GO:0044440 endosomal part
2.31 4.58e-07 GO:0030424 axon
2.24 2.08e-08 GO:0044456 synapse part
2.24 1.32e-03 GO:0030135 coated vesicle
2.15 6.80e-11 GO:0045202 synapse

Gene overrepresentation in function category:

Showing 1 to 20 of 31 entries
Enrichment   P-value GO Accession GO Term
2.53 1.16e-02 GO:0015399 primary active transmembrane transporter activity
2.53 1.16e-02 GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity
2.26 4.68e-06 GO:0005083 small GTPase regulator activity
2.25 3.41e-02 GO:0051020 GTPase binding
2.18 1.88e-02 GO:0015077 monovalent inorganic cation transmembrane transporter activity
2.01 1.10e-02 GO:0005096 GTPase activator activity
2.01 1.85e-02 GO:0022890 inorganic cation transmembrane transporter activity
1.97 7.72e-06 GO:0030695 GTPase regulator activity
1.94 1.30e-05 GO:0060589 nucleoside-triphosphatase regulator activity
1.79 1.57e-02 GO:0022804 active transmembrane transporter activity
1.78 2.07e-02 GO:0008047 enzyme activator activity
1.72 6.85e-04 GO:0008324 cation transmembrane transporter activity
1.65 3.20e-03 GO:0008092 cytoskeletal protein binding
1.61 7.98e-04 GO:0015075 ion transmembrane transporter activity
1.58 4.38e-04 GO:0022891 substrate-specific transmembrane transporter activity
1.54 6.19e-04 GO:0022857 transmembrane transporter activity
1.53 4.96e-04 GO:0022892 substrate-specific transporter activity
1.49 5.08e-03 GO:0030234 enzyme regulator activity
1.47 7.72e-04 GO:0005215 transporter activity
1.45 1.05e-06 GO:0032553 ribonucleotide binding