Motif ID: PAX2.p2

Z-value: 1.322


Transcription factors associated with PAX2.p2:

Gene SymbolEntrez IDGene Name
Pax2 18504 paired box gene 2



Activity profile for motif PAX2.p2.

activity profile for motif PAX2.p2


Sorted Z-values histogram for motif PAX2.p2

Sorted Z-values for motif PAX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_83936038 18.620 Sult4a1
sulfotransferase family 4A, member 1
chr4_-_151851624 14.091 Kcnab2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr4_-_151851574 13.307 NM_010598
Kcnab2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr11_+_69154265 12.847 A030009H04Rik
RIKEN cDNA A030009H04 gene
chr5_-_108978950 11.892 NM_007756
Cplx1
complexin 1
chr11_+_78136681 11.867 Aldoc
aldolase C, fructose-bisphosphate
chr16_-_44139087 10.939 NM_007508
Atp6v1a
ATPase, H+ transporting, lysosomal V1 subunit A
chr11_+_78136690 10.896 Aldoc
aldolase C, fructose-bisphosphate
chrX_-_132602648 10.778 NM_009749
Bex2
brain expressed X-linked 2
chrX_-_20498021 10.436 NM_001110780
NM_013680
Syn1

synapsin I

chr7_-_28338127 8.816 NM_011116
Pld3
phospholipase D family, member 3
chr9_-_64101429 8.417 Map2k1
mitogen-activated protein kinase kinase 1
chr4_-_147412872 8.253 NM_011929
Clcn6
chloride channel 6
chr6_+_116158049 8.218 NM_026585
D6Wsu116e
DNA segment, Chr 6, Wayne State University 116, expressed
chr12_+_88288287 7.684 NM_173735
2310044G17Rik
RIKEN cDNA 2310044G17 gene
chr10_+_110601745 7.680 NM_001003717
NM_175489
Osbpl8

oxysterol binding protein-like 8

chr15_-_83936183 7.501 NM_013873
Sult4a1
sulfotransferase family 4A, member 1
chr9_-_64101138 7.412 Map2k1
mitogen-activated protein kinase kinase 1
chr5_-_124022937 7.323 NM_029929
Vps33a
vacuolar protein sorting 33A (yeast)
chrX_+_149574498 7.291 NM_001004154
Rragb
Ras-related GTP binding B
chr9_-_97933599 7.264 Clstn2
calsyntenin 2
chr9_-_64101354 7.185 NM_008927
Map2k1
mitogen-activated protein kinase kinase 1
chrX_-_132749976 7.013 NM_009052
Bex1
brain expressed gene 1
chr6_+_49772688 6.827 NM_023456
Npy
neuropeptide Y
chr9_-_91260597 6.686 Zic1
zinc finger protein of the cerebellum 1
chr3_+_82162037 6.659 Mtap9
microtubule-associated protein 9
chr9_-_91260619 6.405 NM_009573
Zic1
zinc finger protein of the cerebellum 1
chr4_-_147412919 6.206 Clcn6
chloride channel 6
chr3_+_82162091 6.204 Mtap9
microtubule-associated protein 9
chr13_+_118391270 6.121 Hcn1
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr8_+_128822478 6.035 NM_175434
Slc35f3
solute carrier family 35, member F3
chr6_+_115085096 6.011 Syn2
synapsin II
chr17_-_66426165 5.959 Ankrd12
ankyrin repeat domain 12
chr13_+_46597461 5.957 Cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr12_+_4082573 5.943 NM_153082
Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chrX_+_133200982 5.936 Tceal3
transcription elongation factor A (SII)-like 3
chr3_-_10440061 5.797 NM_001127191
NM_029068
Snx16

sorting nexin 16

chrX_+_133200913 5.778 NM_001029978
Tceal3
transcription elongation factor A (SII)-like 3
chr9_-_97933533 5.738 NM_022319
Clstn2
calsyntenin 2
chr13_-_47110187 5.711 NM_175340
Nhlrc1
NHL repeat containing 1
chr12_+_33505175 5.631 NM_021524
Nampt
nicotinamide phosphoribosyltransferase
chr10_-_18735154 5.575 NM_009397
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr3_-_117063317 5.441 D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr8_-_75877407 5.435 Large
like-glycosyltransferase
chr2_-_74416925 5.383 NM_001110209
NM_027133
Lnp

limb and neural patterns

chr7_-_133942767 5.373 NM_007438
Aldoa
aldolase A, fructose-bisphosphate
chr2_-_25211822 5.370 NM_031843
Dpp7
dipeptidylpeptidase 7
chr3_+_95428870 5.365 NM_001026212
NM_019561
Ensa

endosulfine alpha

chr14_-_30534966 5.356 NM_009785
Cacna2d3
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr17_-_27076365 5.335 NM_026307
NM_026948
Cuta

cutA divalent cation tolerance homolog (E. coli)

chr2_-_164683125 5.309 NM_011125
Pltp
phospholipid transfer protein
chr3_-_87804062 5.226 Bcan
brevican
chr17_+_25270317 5.127 NM_011930
Clcn7
chloride channel 7
chr12_+_4082739 5.123 Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr9_-_103664100 5.112 NM_178638
Tmem108
transmembrane protein 108
chr1_+_154802144 5.101 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr17_+_87506971 5.086 NM_019654
Socs5
suppressor of cytokine signaling 5
chr1_-_177422630 5.077 NM_001199003
NM_011880
Rgs7

regulator of G protein signaling 7

chr1_+_154802091 5.067 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr7_+_94732677 5.029 NM_001081414
NM_001143834
Grm5

glutamate receptor, metabotropic 5

chr8_+_73278577 5.007 NM_001166399
NM_009001
Rab3a

RAB3A, member RAS oncogene family

chr12_+_33505307 4.948 Nampt
nicotinamide phosphoribosyltransferase
chr7_-_25772525 4.936 Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr16_-_20621287 4.929 NM_028420
Camk2n2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chrX_-_131135346 4.926 NM_013463
Gla
galactosidase, alpha
chr4_+_129985957 4.899 NM_010174
Fabp3
fatty acid binding protein 3, muscle and heart
chr9_+_58430210 4.884 Nptn
neuroplastin
chr1_+_24685475 4.864 Lmbrd1
LMBR1 domain containing 1
chr17_+_6106857 4.835 Tulp4
tubby like protein 4
chr5_-_118694869 4.819 NM_172998
NM_001109902
Rnft2

ring finger protein, transmembrane 2

chr1_+_108068405 4.796 NM_133821
Phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chr3_-_87804277 4.796 NM_001109758
NM_007529
Bcan

brevican

chr17_+_6106829 4.751 NM_001103181
Tulp4
tubby like protein 4
chr12_+_33505364 4.738 Nampt
nicotinamide phosphoribosyltransferase
chr6_+_7505070 4.724 NM_009311
Tac1
tachykinin 1
chr13_+_58909254 4.717 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr7_+_134985435 4.684 Stx4a
syntaxin 4A (placental)
chr4_-_117559857 4.673 NM_033617
Atp6v0b
ATPase, H+ transporting, lysosomal V0 subunit B
chr7_+_64845887 4.607 NM_001038701
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr3_+_82161952 4.558 NM_001081230
Mtap9
microtubule-associated protein 9
chr14_-_70205438 4.540 Rhobtb2
Rho-related BTB domain containing 2
chr1_-_94998418 4.520 NM_001110315
NM_008440
Kif1a

kinesin family member 1A

chr18_-_31769504 4.476 NM_026165
Slc25a46
solute carrier family 25, member 46
chr10_-_57252251 4.418 Serinc1
serine incorporator 1
chr17_-_90487479 4.404 Nrxn1
neurexin I
chr6_+_48487648 4.396 Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
chr16_+_94592307 4.389 NM_009441
Ttc3
tetratricopeptide repeat domain 3
chr1_-_177422520 4.380 Rgs7
regulator of G protein signaling 7
chr19_-_6141100 4.375 NM_019722
Arl2
ADP-ribosylation factor-like 2
chr10_-_57252184 4.361 Serinc1
serine incorporator 1
chr4_+_129662110 4.358 Bai2
brain-specific angiogenesis inhibitor 2
chr17_-_27075896 4.348 Cuta
cutA divalent cation tolerance homolog (E. coli)
chr15_+_82105647 4.314 Sept3
septin 3
chr3_+_95428905 4.273 Ensa
endosulfine alpha
chr10_+_67000613 4.202 NM_010118
Egr2
early growth response 2
chr1_+_154802198 4.201 NM_175460
Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr17_+_21082459 4.184 Ppp2r1a
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
chr9_+_89804612 4.151 NM_001039655
NM_011245
Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr3_-_117063090 4.151 D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr17_+_37187550 4.143 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr4_+_43394824 4.142 NM_001037709
Rusc2
RUN and SH3 domain containing 2
chr6_+_129483154 4.140 Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr14_-_51550327 4.126 NM_001033271
Tmem55b
transmembrane protein 55b
chr16_+_94592373 4.119 Ttc3
tetratricopeptide repeat domain 3
chr15_-_84387921 4.105 Ldoc1l
leucine zipper, down-regulated in cancer 1-like
chr4_+_43394949 4.098 Rusc2
RUN and SH3 domain containing 2
chr3_-_80606500 4.070 Gria2
glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr7_+_129432810 4.069 Prkcb
protein kinase C, beta
chr13_+_58909168 4.064 NM_001025074
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr18_+_38115192 4.048 NM_153793
Rell2
RELT-like 2
chr13_+_46597448 4.040 Cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr17_+_37187984 4.027 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr19_+_45122281 4.014 Sfxn3
sideroflexin 3
chr5_+_98609872 4.002 NM_029947
Prdm8
PR domain containing 8
chr2_-_134469754 3.989 Tmx4
thioredoxin-related transmembrane protein 4
chr10_-_57252252 3.985 NM_019760
Serinc1
serine incorporator 1
chr4_+_101223198 3.944 NM_001164583
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr9_-_69989168 3.940 Fam81a
family with sequence similarity 81, member A
chr15_-_84388245 3.910 NM_177630
Ldoc1l
leucine zipper, down-regulated in cancer 1-like
chrX_+_131135770 3.904 NM_019868
Hnrnph2
heterogeneous nuclear ribonucleoprotein H2
chr18_+_40416615 3.902 2900055J20Rik
RIKEN cDNA 2900055J20 gene
chr4_+_42965965 3.895 NM_019874
Dnajb5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr17_+_81343933 3.883 NM_026516
Tmem178
transmembrane protein 178
chr15_-_84388113 3.876 Ldoc1l
leucine zipper, down-regulated in cancer 1-like
chr19_-_6984020 3.874 NM_012021
Prdx5
peroxiredoxin 5
chr13_+_58909236 3.869 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr7_+_134985164 3.858 NM_009294
Stx4a
syntaxin 4A (placental)
chr11_-_90252208 3.850 Hlf
hepatic leukemia factor
chr7_-_133942605 3.808 NM_001177307
Aldoa
aldolase A, fructose-bisphosphate
chr1_-_137064124 3.803 NM_134438
Gpr37l1
G protein-coupled receptor 37-like 1
chr2_+_121121189 3.796 NM_001173506
Mtap1a
microtubule-associated protein 1 A
chr12_-_80273320 3.789 NM_016800
Vti1b
vesicle transport through interaction with t-SNAREs 1B homolog
chr11_+_29592946 3.781 Rtn4
reticulon 4
chr7_+_28338239 3.779 NM_175107
2310022A10Rik
RIKEN cDNA 2310022A10 gene
chr5_-_140865121 3.766 NM_172277
Snx8
sorting nexin 8
chr7_+_16683891 3.766 NM_025898
Napa
N-ethylmaleimide sensitive fusion protein attachment protein alpha
chr3_-_80606641 3.747 Gria2
glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr2_-_167014273 3.740 NM_008420
Kcnb1
potassium voltage gated channel, Shab-related subfamily, member 1
chr2_-_91284778 3.735 NM_175123
1110051M20Rik
RIKEN cDNA 1110051M20 gene
chr9_+_58430031 3.732 NM_009145
Nptn
neuroplastin
chr17_-_66426361 3.686 NM_001025572
Ankrd12
ankyrin repeat domain 12
chr1_-_94998392 3.685 Kif1a
kinesin family member 1A
chr13_+_97841524 3.681 NM_001100458
Fam169a
family with sequence similarity 169, member A
chr6_-_126658429 3.676


chr8_-_67373608 3.643 Klhl2
kelch-like 2, Mayven (Drosophila)
chr15_+_38591604 3.630 NM_025494
Atp6v1c1
ATPase, H+ transporting, lysosomal V1 subunit C1
chr4_-_70195870 3.605 Megf9
multiple EGF-like-domains 9
chr11_+_68901989 3.586 Vamp2
vesicle-associated membrane protein 2
chr3_+_13471681 3.568 Ralyl
RALY RNA binding protein-like
chrX_+_162782484 3.556 NM_001177955
NM_001177956
NM_001177957
NM_001177958
NM_001177959
NM_001177960
Gpm6b





glycoprotein m6b





chrX_+_149574541 3.548 Rragb
Ras-related GTP binding B
chr3_-_107320881 3.525 NM_172271
Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr5_+_137506122 3.511 NM_001039385
Vgf
VGF nerve growth factor inducible
chr2_+_119420031 3.509 1700020I14Rik
RIKEN cDNA 1700020I14 gene
chr11_-_30549383 3.506 NM_029344
Acyp2
acylphosphatase 2, muscle type
chr19_-_6984433 3.501 Prdx5
peroxiredoxin 5
chr4_-_70195952 3.500 NM_172694
Megf9
multiple EGF-like-domains 9
chrX_+_78316003 3.500 Tmem47
transmembrane protein 47
chr6_+_54402876 3.474 NM_001167860
NM_001167861
Wipf3

WAS/WASL interacting protein family, member 3

chr13_+_118391126 3.460 NM_010408
Hcn1
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr16_+_11066390 3.455 NM_009223
Snn
stannin
chr6_+_72047563 3.450 NM_001035228
NM_011375
St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chr2_-_91284827 3.446 1110051M20Rik
RIKEN cDNA 1110051M20 gene
chr14_+_14286471 3.431 NM_001163032
Synpr
synaptoporin
chr19_-_36811137 3.391 Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr9_+_108710676 3.382 NM_030729
Nckipsd
NCK interacting protein with SH3 domain
chr2_-_30141815 3.370 Dolk
dolichol kinase
chr15_+_79921725 3.368 NM_009303
NM_207708
Syngr1

synaptogyrin 1

chr3_+_99966396 3.366 Gdap2
ganglioside-induced differentiation-associated-protein 2
chr14_-_78936606 3.347 NM_001164503
Akap11
A kinase (PRKA) anchor protein 11
chr2_+_129024496 3.338 NM_001159593
NM_015747
Slc20a1

solute carrier family 20, member 1

chr2_+_19579607 3.333 NM_027715
Otud1
OTU domain containing 1
chr3_-_152331083 3.332 NM_001081277
Ak5
adenylate kinase 5
chr4_-_150026205 3.322 NM_173774
Slc45a1
solute carrier family 45, member 1
chr12_+_16660245 3.314 NM_008747
Ntsr2
neurotensin receptor 2
chr17_-_24306262 3.313 NM_009729
Atp6v0c-ps2
Atp6v0c
ATPase, H+ transporting, lysosomal V0 subunit C, pseudogene 2
ATPase, H+ transporting, lysosomal V0 subunit C
chr10_-_79602040 3.296 Dos
downstream of Stk11
chr18_+_23910833 3.262 NM_001162942
Mapre2
microtubule-associated protein, RP/EB family, member 2
chrX_+_33735898 3.259 NM_028325
Zcchc12
zinc finger, CCHC domain containing 12
chr16_-_18343944 3.253 NM_138583
D16H22S680E
DNA segment, Chr 16, human D22S680E, expressed
chrX_+_160346948 3.250 NM_026887
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr17_+_24625709 3.248 NM_027937
Caskin1
CASK interacting protein 1
chr17_+_21082444 3.234 Ppp2r1a
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
chr18_+_35020867 3.227 Egr1
early growth response 1
chr11_+_70658271 3.220 Rabep1
rabaptin, RAB GTPase binding effector protein 1
chr14_-_73725546 3.217 Rb1
retinoblastoma 1
chr2_+_166631011 3.209 NM_001085495
Arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr16_+_6349108 3.197 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr7_-_107806887 3.193 NM_001163183
NM_001163184
NM_001163185
Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr15_-_91403685 3.192 NM_001033633
Slc2a13
solute carrier family 2 (facilitated glucose transporter), member 13
chr18_+_35020859 3.192 NM_007913
Egr1
early growth response 1
chr13_+_64533703 3.184 NM_053180
Cdk20
cyclin-dependent kinase 20
chr17_-_87846158 3.157 NM_007589
Calm2
calmodulin 2
chr14_-_16271386 3.149 NM_146052
Lrrc3b
leucine rich repeat containing 3B
chr9_-_69989285 3.143 NM_029784
Fam81a
family with sequence similarity 81, member A
chr9_+_59598963 3.138 NM_173018
Myo9a
myosin IXa
chr3_+_28680248 3.137 Eif5a2
eukaryotic translation initiation factor 5A2
chr5_+_110973321 3.137 NM_198306
Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr18_+_64425037 3.115 St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr11_-_86570918 3.109 NM_001003908
Cltc
clathrin, heavy polypeptide (Hc)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.51 1.71e-17 GO:0051179 localization
1.55 1.65e-16 GO:0051234 establishment of localization
1.55 1.73e-16 GO:0006810 transport
1.72 1.21e-10 GO:0033036 macromolecule localization
1.78 2.31e-10 GO:0008104 protein localization
1.88 1.11e-09 GO:0015031 protein transport
1.86 1.36e-09 GO:0045184 establishment of protein localization
1.81 4.01e-09 GO:0051649 establishment of localization in cell
1.72 8.37e-09 GO:0051641 cellular localization
1.23 3.75e-08 GO:0044237 cellular metabolic process
2.13 5.52e-06 GO:0019226 transmission of nerve impulse
2.13 5.52e-06 GO:0035637 multicellular organismal signaling
1.81 7.51e-06 GO:0046907 intracellular transport
1.81 8.26e-06 GO:0016192 vesicle-mediated transport
1.17 5.50e-05 GO:0008152 metabolic process
1.10 5.70e-05 GO:0009987 cellular process
2.17 1.05e-04 GO:0007268 synaptic transmission
1.18 1.17e-04 GO:0044238 primary metabolic process
1.71 1.43e-04 GO:0007154 cell communication
1.30 2.22e-04 GO:0016043 cellular component organization
1.38 4.51e-04 GO:0065008 regulation of biological quality
2.96 7.81e-04 GO:0006836 neurotransmitter transport
4.00 7.86e-04 GO:0007269 neurotransmitter secretion
1.28 8.94e-04 GO:0071840 cellular component organization or biogenesis
3.13 1.21e-03 GO:0001505 regulation of neurotransmitter levels
1.33 1.75e-03 GO:0071842 cellular component organization at cellular level
1.49 2.17e-03 GO:0035556 intracellular signal transduction
2.11 2.41e-03 GO:0006091 generation of precursor metabolites and energy
1.40 3.34e-03 GO:0023051 regulation of signaling
1.77 4.47e-03 GO:0016044 cellular membrane organization
1.31 4.67e-03 GO:0071841 cellular component organization or biogenesis at cellular level
4.78 4.77e-03 GO:0015988 energy coupled proton transport, against electrochemical gradient
4.78 4.77e-03 GO:0015991 ATP hydrolysis coupled proton transport
1.70 5.18e-03 GO:0030001 metal ion transport
1.73 5.30e-03 GO:0070727 cellular macromolecule localization
1.76 5.35e-03 GO:0061024 membrane organization
1.39 5.85e-03 GO:0006996 organelle organization
1.38 6.94e-03 GO:0065009 regulation of molecular function
1.76 7.29e-03 GO:0007267 cell-cell signaling
1.86 7.45e-03 GO:0006886 intracellular protein transport
4.60 7.83e-03 GO:0007040 lysosome organization
1.72 8.00e-03 GO:0034613 cellular protein localization
1.70 8.27e-03 GO:0006753 nucleoside phosphate metabolic process
1.70 8.27e-03 GO:0009117 nucleotide metabolic process
3.60 9.03e-03 GO:0007033 vacuole organization
3.61 1.75e-02 GO:0048168 regulation of neuronal synaptic plasticity
1.20 1.97e-02 GO:0019222 regulation of metabolic process
1.77 2.30e-02 GO:0006163 purine nucleotide metabolic process
1.63 2.66e-02 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.98 2.92e-02 GO:0031644 regulation of neurological system process
4.14 2.96e-02 GO:0015682 ferric iron transport
4.14 2.96e-02 GO:0033572 transferrin transport
1.93 3.42e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.58 3.52e-02 GO:0006812 cation transport
1.40 3.53e-02 GO:0050790 regulation of catalytic activity
1.18 3.68e-02 GO:0044260 cellular macromolecule metabolic process
2.05 4.10e-02 GO:0050804 regulation of synaptic transmission
1.71 4.17e-02 GO:0072521 purine-containing compound metabolic process
1.83 4.78e-02 GO:0009150 purine ribonucleotide metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.34 4.27e-32 GO:0005737 cytoplasm
1.25 1.95e-30 GO:0005622 intracellular
1.24 3.09e-28 GO:0044424 intracellular part
1.42 2.52e-26 GO:0044444 cytoplasmic part
1.27 2.43e-20 GO:0043227 membrane-bounded organelle
1.27 2.93e-20 GO:0043231 intracellular membrane-bounded organelle
1.24 5.05e-20 GO:0043229 intracellular organelle
1.24 6.24e-20 GO:0043226 organelle
1.11 1.12e-14 GO:0005623 cell
1.11 1.12e-14 GO:0044464 cell part
2.14 7.81e-13 GO:0043005 neuron projection
2.65 2.94e-12 GO:0005773 vacuole
2.15 6.80e-11 GO:0045202 synapse
1.68 1.08e-10 GO:0031090 organelle membrane
2.62 9.25e-10 GO:0000323 lytic vacuole
2.62 9.25e-10 GO:0005764 lysosome
2.12 3.06e-09 GO:0005768 endosome
2.24 2.08e-08 GO:0044456 synapse part
1.69 2.46e-08 GO:0005794 Golgi apparatus
1.28 1.03e-07 GO:0044422 organelle part
1.28 1.44e-07 GO:0044446 intracellular organelle part
2.31 4.58e-07 GO:0030424 axon
1.50 6.73e-07 GO:0005829 cytosol
1.55 1.09e-06 GO:0000267 cell fraction
1.56 2.59e-06 GO:0042995 cell projection
2.11 1.59e-05 GO:0030425 dendrite
3.83 2.72e-05 GO:0030665 clathrin coated vesicle membrane
1.31 2.94e-05 GO:0043234 protein complex
1.54 1.07e-04 GO:0005626 insoluble fraction
2.48 1.51e-04 GO:0030136 clathrin-coated vesicle
1.82 1.97e-04 GO:0044463 cell projection part
1.54 2.04e-04 GO:0005624 membrane fraction
2.51 2.41e-04 GO:0019717 synaptosome
1.24 7.01e-04 GO:0032991 macromolecular complex
3.10 7.47e-04 GO:0030662 coated vesicle membrane
2.72 7.74e-04 GO:0008021 synaptic vesicle
2.43 1.11e-03 GO:0033267 axon part
5.45 1.32e-03 GO:0033176 proton-transporting V-type ATPase complex
2.24 1.32e-03 GO:0030135 coated vesicle
2.98 1.58e-03 GO:0044437 vacuolar part
1.37 1.62e-03 GO:0005739 mitochondrion
1.53 1.95e-03 GO:0031982 vesicle
1.52 2.18e-03 GO:0012505 endomembrane system
4.28 3.24e-03 GO:0030672 synaptic vesicle membrane
1.52 4.86e-03 GO:0031410 cytoplasmic vesicle
2.89 7.26e-03 GO:0005774 vacuolar membrane
2.42 1.12e-02 GO:0010008 endosome membrane
2.42 1.12e-02 GO:0044440 endosomal part
3.36 2.84e-02 GO:0042734 presynaptic membrane
1.54 3.07e-02 GO:0031988 membrane-bounded vesicle
1.75 3.32e-02 GO:0044431 Golgi apparatus part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.19 6.05e-16 GO:0005488 binding
1.32 3.25e-15 GO:0005515 protein binding
1.45 1.05e-06 GO:0032553 ribonucleotide binding
1.44 1.45e-06 GO:0017076 purine nucleotide binding
1.44 1.60e-06 GO:0032555 purine ribonucleotide binding
1.45 1.68e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.39 1.94e-06 GO:0000166 nucleotide binding
2.26 4.68e-06 GO:0005083 small GTPase regulator activity
1.97 7.72e-06 GO:0030695 GTPase regulator activity
1.94 1.30e-05 GO:0060589 nucleoside-triphosphatase regulator activity
1.21 2.36e-05 GO:0003824 catalytic activity
1.41 3.11e-04 GO:0030554 adenyl nucleotide binding
1.41 3.40e-04 GO:0032559 adenyl ribonucleotide binding
1.58 4.38e-04 GO:0022891 substrate-specific transmembrane transporter activity
1.53 4.96e-04 GO:0022892 substrate-specific transporter activity
1.41 5.62e-04 GO:0005524 ATP binding
1.54 6.19e-04 GO:0022857 transmembrane transporter activity
1.72 6.85e-04 GO:0008324 cation transmembrane transporter activity
1.47 7.72e-04 GO:0005215 transporter activity
1.61 7.98e-04 GO:0015075 ion transmembrane transporter activity
1.65 3.20e-03 GO:0008092 cytoskeletal protein binding
1.49 5.08e-03 GO:0030234 enzyme regulator activity
2.01 1.10e-02 GO:0005096 GTPase activator activity
2.53 1.16e-02 GO:0015399 primary active transmembrane transporter activity
2.53 1.16e-02 GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity
1.79 1.57e-02 GO:0022804 active transmembrane transporter activity
2.01 1.85e-02 GO:0022890 inorganic cation transmembrane transporter activity
2.18 1.88e-02 GO:0015077 monovalent inorganic cation transmembrane transporter activity
1.78 2.07e-02 GO:0008047 enzyme activator activity
1.45 2.44e-02 GO:0019899 enzyme binding
2.25 3.41e-02 GO:0051020 GTPase binding