Motif ID: PAX4.p2

Z-value: 1.229


Transcription factors associated with PAX4.p2:

Gene SymbolEntrez IDGene Name
Pax4 18506 paired box gene 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax4chr6_-_28399248-0.281.2e-04Click!


Activity profile for motif PAX4.p2.

activity profile for motif PAX4.p2


Sorted Z-values histogram for motif PAX4.p2

Sorted Z-values for motif PAX4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_9014351 18.464 Cybb
cytochrome b-245, beta polypeptide
chr5_+_67067477 15.329 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr4_+_102242664 15.226 NM_001177980
Pde4b
phosphodiesterase 4B, cAMP specific
chr5_+_67067497 15.200 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr16_-_36666078 14.956 NM_019388
Cd86
CD86 antigen
chr5_+_67067359 14.623 NM_011670
Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr11_-_83343962 10.798 NM_013653
Ccl5
chemokine (C-C motif) ligand 5
chr12_+_118896501 10.267 Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
chr1_+_90031368 9.809 NM_145079
Ugt1a6a
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr14_-_13655592 9.766 NM_001042617
NM_012061
Cadps

Ca2+-dependent secretion activator

chr14_-_13655558 9.711 Cadps
Ca2+-dependent secretion activator
chr6_+_137359231 9.464 NM_001164402
NM_001164403
Ptpro

protein tyrosine phosphatase, receptor type, O

chr1_+_89999782 9.278 NM_201410
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr5_+_91201521 9.228 Pf4
platelet factor 4
chr5_+_30960594 9.145


chr5_+_91201538 8.854 Pf4
platelet factor 4
chr5_-_92776160 8.841 Cxcl10
chemokine (C-X-C motif) ligand 10
chr6_+_113433507 8.731 NM_133930
Creld1
cysteine-rich with EGF-like domains 1
chr14_-_67422871 8.447 Dpysl2
dihydropyrimidinase-like 2
chr5_+_91201460 8.225 NM_019932
Pf4
platelet factor 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
6.95 5.68e-03 GO:0030433 ER-associated protein catabolic process
2.83 8.50e-03 GO:0010975 regulation of neuron projection development
2.64 1.33e-02 GO:0031344 regulation of cell projection organization
2.43 4.01e-02 GO:0051129 negative regulation of cellular component organization
2.40 9.43e-03 GO:0045664 regulation of neuron differentiation
2.17 2.99e-02 GO:0050767 regulation of neurogenesis
1.63 2.40e-02 GO:0032879 regulation of localization
1.44 3.79e-04 GO:0051234 establishment of localization
1.43 2.37e-05 GO:0051179 localization
1.43 7.79e-04 GO:0006810 transport

Gene overrepresentation in compartment category:

Showing 1 to 20 of 24 entries
Enrichment   P-value GO Accession GO Term
2.66 4.74e-02 GO:0019717 synaptosome
1.84 6.44e-03 GO:0043005 neuron projection
1.76 2.99e-04 GO:0005626 insoluble fraction
1.74 1.25e-05 GO:0000267 cell fraction
1.72 1.40e-03 GO:0005624 membrane fraction
1.69 1.54e-03 GO:0005794 Golgi apparatus
1.64 1.28e-03 GO:0042995 cell projection
1.61 1.18e-03 GO:0031090 organelle membrane
1.48 1.08e-02 GO:0005829 cytosol
1.46 1.45e-08 GO:0071944 cell periphery
1.46 1.80e-02 GO:0005739 mitochondrion
1.45 2.47e-14 GO:0044444 cytoplasmic part
1.45 6.15e-08 GO:0005886 plasma membrane
1.41 2.41e-02 GO:0044459 plasma membrane part
1.37 9.84e-19 GO:0005737 cytoplasm
1.26 7.62e-16 GO:0005622 intracellular
1.25 1.07e-14 GO:0044424 intracellular part
1.23 3.35e-08 GO:0043229 intracellular organelle
1.23 3.74e-08 GO:0043226 organelle
1.23 1.01e-06 GO:0043227 membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
1.34 4.88e-08 GO:0005515 protein binding
1.17 2.59e-06 GO:0005488 binding