Motif ID: PAX5.p2

Z-value: 1.124


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
Pax5 18507 paired box gene 5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax5chr4_-_44723311-0.145.1e-02Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_159326220 16.148 NM_025932
 Syap1
synapse associated protein 1
chrX_+_139115908 9.590 NM_177592
 Tmem164
transmembrane protein 164
chr9_+_123387818 8.818 NM_013860
 Limd1
LIM domains containing 1
chr17_+_24889931 8.199 NM_001012402
 Hs3st6
heparan sulfate (glucosamine) 3-O-sulfotransferase 6
chr2_+_71624985 8.087 NM_008397
 Itga6
integrin alpha 6
chr2_-_26459710 7.902 NM_026212
 Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr2_-_169956719 7.079 NM_001033299
 Zfp217
zinc finger protein 217
chr3_-_79371600 7.000 NM_001162999
 Fnip2
folliculin interacting protein 2
chr2_-_26459777 6.688 Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr7_-_142908061 6.218 NM_001081117
 Mki67
antigen identified by monoclonal antibody Ki 67
chr4_-_141640159 6.033 NM_145402
 Tmem51
transmembrane protein 51
chr2_+_32731648 5.889 NM_146119
 Fam129b
family with sequence similarity 129, member B
chr17_-_74694322 5.839 Memo1
mediator of cell motility 1
chr10_-_7500674 5.702 NM_145418
 BC013529
cDNA sequence BC013529
chr4_+_155336386 5.659 NM_026125
 Fam132a
family with sequence similarity 132, member A
chr6_+_17231334 5.566 NM_016900
 Cav2
caveolin 2
chr4_+_155336456 5.351 Fam132a
family with sequence similarity 132, member A
chr17_-_13185014 5.320 Wtap
Wilms' tumour 1-associating protein
chr2_+_18598644 5.167 NM_007552
 Bmi1
Bmi1 polycomb ring finger oncogene
chr4_+_136833403 5.103 NM_009523
 Wnt4
wingless-related MMTV integration site 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 438 entries
Enrichment   P-value GO Accession GO Term
4.68 2.07e-02 GO:0003170 heart valve development
3.58 9.03e-03 GO:0009950 dorsal/ventral axis specification
3.12 3.03e-05 GO:0048286 lung alveolus development
3.06 7.86e-03 GO:0048538 thymus development
2.91 4.44e-04 GO:0061035 regulation of cartilage development
2.87 8.10e-03 GO:0060603 mammary gland duct morphogenesis
2.85 3.48e-05 GO:0061180 mammary gland epithelium development
2.83 8.98e-04 GO:0035567 non-canonical Wnt receptor signaling pathway
2.72 4.49e-02 GO:0045931 positive regulation of mitotic cell cycle
2.67 3.04e-06 GO:0060070 canonical Wnt receptor signaling pathway
2.66 1.47e-03 GO:0060443 mammary gland morphogenesis
2.64 4.62e-14 GO:0030324 lung development
2.63 3.11e-14 GO:0030323 respiratory tube development
2.63 6.58e-04 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.60 3.61e-02 GO:0045669 positive regulation of osteoblast differentiation
2.59 3.40e-15 GO:0060541 respiratory system development
2.56 2.58e-05 GO:0001942 hair follicle development
2.56 2.58e-05 GO:0022404 molting cycle process
2.56 2.58e-05 GO:0022405 hair cycle process
2.52 2.96e-05 GO:0001892 embryonic placenta development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 71 entries
Enrichment   P-value GO Accession GO Term
4.68 1.32e-02 GO:0000145 exocyst
3.68 5.19e-03 GO:0000932 cytoplasmic mRNA processing body
2.55 9.46e-04 GO:0032432 actin filament bundle
2.51 3.71e-03 GO:0001725 stress fiber
2.37 2.49e-06 GO:0005924 cell-substrate adherens junction
2.37 5.69e-06 GO:0005925 focal adhesion
2.34 1.07e-02 GO:0017053 transcriptional repressor complex
2.34 1.07e-02 GO:0042641 actomyosin
2.34 1.63e-02 GO:0005643 nuclear pore
2.26 9.79e-06 GO:0030055 cell-substrate junction
2.22 9.35e-09 GO:0000775 chromosome, centromeric region
2.21 3.19e-08 GO:0005912 adherens junction
2.18 1.14e-04 GO:0000776 kinetochore
2.09 2.96e-07 GO:0070161 anchoring junction
2.08 2.21e-02 GO:0000792 heterochromatin
2.06 4.98e-02 GO:0046930 pore complex
1.94 3.16e-07 GO:0005635 nuclear envelope
1.92 2.72e-02 GO:0031965 nuclear membrane
1.91 3.08e-06 GO:0031252 cell leading edge
1.91 4.00e-02 GO:0016585 chromatin remodeling complex

Gene overrepresentation in function category:

Showing 1 to 20 of 72 entries
Enrichment   P-value GO Accession GO Term
3.83 3.99e-02 GO:0070411 I-SMAD binding
3.68 9.59e-03 GO:0030332 cyclin binding
3.64 6.18e-04 GO:0042813 Wnt receptor activity
3.56 9.82e-06 GO:0017147 Wnt-protein binding
2.88 1.27e-02 GO:0018024 histone-lysine N-methyltransferase activity
2.84 8.69e-03 GO:0016278 lysine N-methyltransferase activity
2.84 8.69e-03 GO:0016279 protein-lysine N-methyltransferase activity
2.54 2.39e-02 GO:0042054 histone methyltransferase activity
2.38 2.32e-03 GO:0046332 SMAD binding
2.21 2.75e-05 GO:0003714 transcription corepressor activity
2.21 3.09e-02 GO:0008276 protein methyltransferase activity
2.09 5.13e-03 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
2.02 9.70e-03 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.96 3.17e-14 GO:0016563 transcription activator activity
1.96 3.69e-08 GO:0003682 chromatin binding
1.96 1.94e-03 GO:0019838 growth factor binding
1.94 5.10e-13 GO:0016564 transcription repressor activity
1.91 7.65e-12 GO:0008134 transcription factor binding
1.82 3.03e-02 GO:0035091 phosphatidylinositol binding
1.81 3.06e-05 GO:0010843 promoter binding