Motif ID: PBX1.p2

Z-value: 1.273


Transcription factors associated with PBX1.p2:

Gene SymbolEntrez IDGene Name
Pbx1 18514 pre B-cell leukemia transcription factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pbx1chr1_-_170362298-0.214.3e-03Click!


Activity profile for motif PBX1.p2.

activity profile for motif PBX1.p2


Sorted Z-values histogram for motif PBX1.p2

Sorted Z-values for motif PBX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PBX1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_65738168 29.416 2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr9_+_65738150 27.927 2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr5_+_111268995 26.002 Chek2
CHK2 checkpoint homolog (S. pombe)
chr13_-_21925343 25.189 NM_178185
NM_001177544
 Hist1h2ah
Hist1h2ap
Hist1h2ai
Hist1h2ao
histone cluster 1, H2ah
histone cluster 1, H2ap
histone cluster 1, H2ai
histone cluster 1, H2ao
chr13_+_23666249 24.790 NM_178188
 Hist1h2ad
Hist1h2ai
histone cluster 1, H2ad
histone cluster 1, H2ai
chr9_+_65738129 24.010 NM_026515
 2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr8_-_4779533 23.719 NM_011369
 Shcbp1
Shc SH2-domain binding protein 1
chr2_-_172195998 21.695 NM_011497
 Aurka
aurora kinase A
chr13_-_23775827 21.668 NM_178189
 Hist1h2ac
histone cluster 1, H2ac
chr5_+_111269020 21.460 NM_016681
 Chek2
CHK2 checkpoint homolog (S. pombe)
chr2_+_164595447 20.463 Ube2c
ubiquitin-conjugating enzyme E2C
chr2_+_164595415 18.181 NM_026785
 Ube2c
ubiquitin-conjugating enzyme E2C
chr16_-_15637390 14.150 NM_008565
 Mcm4
minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chr11_-_40568524 13.644 Ccng1
cyclin G1
chr5_-_111268743 13.223 NM_153571
 Hscb
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr11_-_40568710 12.710 NM_009831
 Ccng1
cyclin G1
chr8_+_59990639 12.140 NM_008252
 Hmgb2
high mobility group box 2
chrX_-_71470766 11.998 Flna
filamin, alpha
chr1_-_45559866 11.715 Col5a2
collagen, type V, alpha 2
chr1_-_45559904 11.439 Col5a2
collagen, type V, alpha 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 64 entries
Enrichment   P-value GO Accession GO Term
3.74 2.92e-03 GO:0045165 cell fate commitment
3.74 4.14e-02 GO:0001503 ossification
3.49 6.98e-04 GO:0000087 M phase of mitotic cell cycle
3.25 7.22e-03 GO:0000280 nuclear division
3.25 7.22e-03 GO:0007067 mitosis
3.25 3.73e-02 GO:0009952 anterior/posterior pattern formation
3.12 1.33e-02 GO:0048285 organelle fission
3.11 1.34e-04 GO:0000279 M phase
3.00 1.47e-05 GO:0022403 cell cycle phase
2.96 1.39e-04 GO:0000278 mitotic cell cycle
2.69 1.17e-05 GO:0022402 cell cycle process
2.51 9.76e-07 GO:0007049 cell cycle
2.41 3.99e-03 GO:0048646 anatomical structure formation involved in morphogenesis
2.41 8.10e-03 GO:0006259 DNA metabolic process
2.38 1.05e-02 GO:0043009 chordate embryonic development
2.35 1.42e-02 GO:0009792 embryo development ending in birth or egg hatching
2.22 1.29e-04 GO:0009888 tissue development
2.16 2.54e-02 GO:0009887 organ morphogenesis
1.98 3.11e-02 GO:0009790 embryo development
1.79 3.69e-08 GO:0010468 regulation of gene expression

Gene overrepresentation in compartment category:

Showing 1 to 20 of 27 entries
Enrichment   P-value GO Accession GO Term
9.70 6.13e-03 GO:0042611 MHC protein complex
5.01 2.79e-03 GO:0032993 protein-DNA complex
4.27 6.01e-03 GO:0000793 condensed chromosome
4.13 3.71e-02 GO:0000776 kinetochore
3.42 2.86e-02 GO:0000775 chromosome, centromeric region
2.88 3.54e-06 GO:0005694 chromosome
2.69 1.67e-04 GO:0044427 chromosomal part
1.92 1.44e-03 GO:0005654 nucleoplasm
1.80 2.97e-04 GO:0031981 nuclear lumen
1.72 3.19e-04 GO:0031974 membrane-enclosed lumen
1.70 9.51e-04 GO:0070013 intracellular organelle lumen
1.69 1.02e-03 GO:0043233 organelle lumen
1.68 7.01e-04 GO:0044428 nuclear part
1.62 1.09e-12 GO:0005634 nucleus
1.59 4.83e-09 GO:0044422 organelle part
1.59 6.51e-09 GO:0044446 intracellular organelle part
1.58 4.51e-04 GO:0043228 non-membrane-bounded organelle
1.58 4.51e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.46 7.88e-03 GO:0043234 protein complex
1.45 1.40e-03 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
2.98 2.14e-02 GO:0003682 chromatin binding
1.95 8.81e-08 GO:0003677 DNA binding
1.94 1.71e-02 GO:0001071 nucleic acid binding transcription factor activity
1.94 1.71e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.79 1.67e-08 GO:0003676 nucleic acid binding
1.65 1.68e-02 GO:0005524 ATP binding
1.64 1.82e-02 GO:0030554 adenyl nucleotide binding
1.62 2.83e-02 GO:0032559 adenyl ribonucleotide binding
1.49 3.27e-02 GO:0000166 nucleotide binding
1.24 3.75e-07 GO:0005488 binding