Motif ID: POU2F1..3.p2

Z-value: 1.588


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
Pou2f1 18986 POU domain, class 2, transcription factor 1
Pou2f2 18987 POU domain, class 2, transcription factor 2
Pou2f3 18988 POU domain, class 2, transcription factor 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou2f2chr7_-_259174580.464.7e-11Click!
Pou2f1chr1_-_1678650300.121.1e-01Click!
Pou2f3chr9_-_43013831-0.009.7e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_23775827 32.197 NM_178189
 Hist1h2ac
histone cluster 1, H2ac
chr13_+_23838602 28.552 NM_175664
 Hist1h2bb
histone cluster 1, H2bb
chr6_+_68375560 27.796 Igkv16-104
immunoglobulin kappa variable 16-104
chr19_-_41069024 25.002 NM_008528
 Blnk
B-cell linker
chr19_-_41068625 24.088 Blnk
B-cell linker
chr3_-_96044172 23.119 NM_013549
NM_178212
 Hist2h2aa1
Hist2h2aa2
histone cluster 2, H2aa1
histone cluster 2, H2aa2
chr2_-_180008165 20.184 NM_145851
 Cables2
CDK5 and Abl enzyme substrate 2
chr3_+_96049419 19.403 NM_013549
NM_178212
 Hist2h3c1
Hist2h2aa1
Hist2h2aa2
histone cluster 2, H3c1
histone cluster 2, H2aa1
histone cluster 2, H2aa2
chr6_+_70557402 18.267


chr6_+_67846144 17.211


chr13_-_22127419 17.168 NM_175659
 Hist1h2ah
histone cluster 1, H2ah
chr13_-_21879086 16.768 NM_178184
 Hist1h2an
histone cluster 1, H2an
chr13_-_22134795 16.708 NM_178186
 Hist1h2ag
Hist1h2ai
histone cluster 1, H2ag
histone cluster 1, H2ai
chr6_+_70648433 16.690 Igkv3-2
immunoglobulin kappa variable 3-2
chr19_+_9016335 16.526 NM_011842
 Mta2
metastasis-associated gene family, member 2
chr13_-_23663006 16.165 NM_178187
 Hist1h2ae
histone cluster 1, H2ae
chr4_+_3605207 15.757 NM_001111096
NM_010747
 Lyn

Yamaguchi sarcoma viral (v-yes-1) oncogene homolog

chr19_+_12535268 15.202 NM_010821
 Mpeg1
macrophage expressed gene 1
chr13_+_21902235 15.101 NM_178185
NM_001177544
 Hist1h2ah
Hist1h2ap
Hist1h2ai
Hist1h2ao
histone cluster 1, H2ah
histone cluster 1, H2ap
histone cluster 1, H2ai
histone cluster 1, H2ao
chr13_+_23666249 14.800 NM_178188
 Hist1h2ad
Hist1h2ai
histone cluster 1, H2ad
histone cluster 1, H2ai

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 31 entries
Enrichment   P-value GO Accession GO Term
9.27 2.67e-05 GO:0071824 protein-DNA complex subunit organization
9.25 5.25e-04 GO:0006334 nucleosome assembly
9.02 1.54e-04 GO:0034728 nucleosome organization
8.86 1.83e-04 GO:0065004 protein-DNA complex assembly
8.26 1.43e-03 GO:0031497 chromatin assembly
8.16 4.11e-04 GO:0006333 chromatin assembly or disassembly
5.91 8.51e-03 GO:0006323 DNA packaging
5.64 3.56e-02 GO:0042113 B cell activation
2.81 4.16e-02 GO:0006325 chromatin organization
2.35 3.04e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.35 6.12e-04 GO:0002376 immune system process
2.31 3.37e-02 GO:0010629 negative regulation of gene expression
2.04 3.75e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.99 4.11e-02 GO:0009892 negative regulation of metabolic process
1.94 4.04e-04 GO:0006351 transcription, DNA-dependent
1.93 4.30e-04 GO:0032774 RNA biosynthetic process
1.84 1.80e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.84 8.45e-05 GO:0006355 regulation of transcription, DNA-dependent
1.82 9.24e-05 GO:0051252 regulation of RNA metabolic process
1.81 2.66e-05 GO:0010556 regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
16.78 1.02e-13 GO:0000786 nucleosome
10.54 3.15e-10 GO:0032993 protein-DNA complex
4.65 5.62e-06 GO:0000785 chromatin
2.76 3.46e-03 GO:0044427 chromosomal part
2.66 3.92e-03 GO:0005694 chromosome
1.60 4.24e-08 GO:0005634 nucleus
1.25 8.95e-03 GO:0043231 intracellular membrane-bounded organelle
1.25 1.02e-02 GO:0043227 membrane-bounded organelle
1.22 1.71e-02 GO:0043226 organelle
1.21 2.10e-02 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
2.67 1.09e-05 GO:0001071 nucleic acid binding transcription factor activity
2.67 1.09e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
2.46 2.01e-05 GO:0030528 transcription regulator activity
2.36 5.14e-03 GO:0043565 sequence-specific DNA binding
2.25 7.34e-09 GO:0003677 DNA binding
1.86 1.07e-06 GO:0003676 nucleic acid binding
1.20 1.03e-02 GO:0005488 binding