• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: POU2F1..3.p2

Z-value: 1.588

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr13_-_23775827	32.197	NM_178189	Hist1h2ac	histone cluster 1, H2ac
chr13_+_23838602	28.552	NM_175664	Hist1h2bb	histone cluster 1, H2bb
chr6_+_68375560	27.796		Igkv16-104	immunoglobulin kappa variable 16-104
chr19_-_41069024	25.002	NM_008528	Blnk	B-cell linker
chr19_-_41068625	24.088		Blnk	B-cell linker
chr3_-_96044172	23.119	NM_013549 NM_178212	Hist2h2aa1 Hist2h2aa2	histone cluster 2, H2aa1 histone cluster 2, H2aa2
chr2_-_180008165	20.184	NM_145851	Cables2	CDK5 and Abl enzyme substrate 2
chr3_+_96049419	19.403	NM_013549 NM_178212	Hist2h3c1 Hist2h2aa1 Hist2h2aa2	histone cluster 2, H3c1 histone cluster 2, H2aa1 histone cluster 2, H2aa2
chr6_+_70557402	18.267
chr6_+_67846144	17.211
chr13_-_22127419	17.168	NM_175659	Hist1h2ah	histone cluster 1, H2ah
chr13_-_21879086	16.768	NM_178184	Hist1h2an	histone cluster 1, H2an
chr13_-_22134795	16.708	NM_178186	Hist1h2ag Hist1h2ai	histone cluster 1, H2ag histone cluster 1, H2ai
chr6_+_70648433	16.690		Igkv3-2	immunoglobulin kappa variable 3-2
chr19_+_9016335	16.526	NM_011842	Mta2	metastasis-associated gene family, member 2
chr13_-_23663006	16.165	NM_178187	Hist1h2ae	histone cluster 1, H2ae
chr4_+_3605207	15.757	NM_001111096 NM_010747	Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
chr19_+_12535268	15.202	NM_010821	Mpeg1	macrophage expressed gene 1
chr13_+_21902235	15.101	NM_178185 NM_001177544	Hist1h2ah Hist1h2ap Hist1h2ai Hist1h2ao	histone cluster 1, H2ah histone cluster 1, H2ap histone cluster 1, H2ai histone cluster 1, H2ao
chr13_+_23666249	14.800	NM_178188	Hist1h2ad Hist1h2ai	histone cluster 1, H2ad histone cluster 1, H2ai
chr15_-_74593991	14.798	NM_010742	Ly6d	lymphocyte antigen 6 complex, locus D
chr6_-_69765093	14.210
chr13_-_23677831	14.073		Hist1h2be	histone cluster 1, H2be
chr13_+_21813912	14.065	NM_178200	Hist1h2bm	histone cluster 1, H2bm
chr13_+_22127689	13.993	NM_175665	Hist1h2bk	histone cluster 1, H2bk
chr13_+_23663264	13.962	NM_178196	Hist1h2bg	histone cluster 1, H2bg
chr13_-_23635220	13.729	NM_178197	Hist1h2bh	histone cluster 1, H2bh
chr19_+_9016466	13.388		Mta2	metastasis-associated gene family, member 2
chr13_-_23666058	13.285	NM_178195	Hist1h2bf	histone cluster 1, H2bf
chr11_-_106175797	13.213	NM_008339	Cd79b	CD79B antigen
chr8_+_71404491	12.359		Lpl	lipoprotein lipase
chr17_+_29627697	12.201		Pim1	proviral integration site 1
chr13_+_23776066	12.164	NM_023422	Hist1h2bc	histone cluster 1, H2bc
chr13_+_22135065	12.084	NM_178198	Hist1h2bj	histone cluster 1, H2bj
chr12_-_115286643	11.741		Igh-V11	immunoglobulin heavy chain (V11 family)
chr7_+_129432585	11.589	NM_008855	Prkcb	protein kinase C, beta
chr4_-_106812064	11.049		2210012G02Rik	RIKEN cDNA 2210012G02 gene
chr8_+_71404452	10.545	NM_008509	Lpl	lipoprotein lipase
chr5_-_109987907	10.499	NM_001164735 NM_016715	Crlf2	cytokine receptor-like factor 2
chr13_-_21925343	10.224	NM_178185 NM_001177544	Hist1h2ah Hist1h2ap Hist1h2ai Hist1h2ao	histone cluster 1, H2ah histone cluster 1, H2ap histone cluster 1, H2ai histone cluster 1, H2ao
chr17_+_29627950	9.998	NM_008842	Pim1	proviral integration site 1
chr13_-_24026024	9.835	NM_175663	Hist1h2ba	histone cluster 1, H2ba
chr6_+_123073333	9.662	NM_001170333 NM_011999	Clec4a2	C-type lectin domain family 4, member a2
chr13_+_103483611	9.624	NM_008533	Cd180	CD180 antigen
chr9_+_108893946	9.606	NM_173019	Pfkfb4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr10_+_75411056	9.290	NM_009514	Vpreb3	pre-B lymphocyte gene 3
chr1_-_167865030	9.189	NM_198933 NM_198934	Pou2f1	POU domain, class 2, transcription factor 1
chr11_-_70468061	8.894		Pfn1	profilin 1
chr11_+_33946927	8.678		Lcp2	lymphocyte cytosolic protein 2
chr3_-_96024766	8.498	NM_175662	Hist2h2ac	histone cluster 2, H2ac
chr1_+_133534852	8.489	NM_007799	Ctse	cathepsin E
chr11_-_86621130	8.150	NM_026191	Dhx40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chrX_-_163647088	7.700	NM_021278	Tmsb4x	thymosin, beta 4, X chromosome
chr15_+_78778153	7.540	NM_001039155 NM_001039156 NM_138579	Triobp	TRIO and F-actin binding protein
chrX_-_163647057	7.479		Tmsb4x	thymosin, beta 4, X chromosome
chr6_-_135197901	7.470	NM_001080552	Gsg1	germ cell-specific gene 1
chr11_-_86621074	7.461		Dhx40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr12_-_35213738	7.410	NM_024124	Hdac9	histone deacetylase 9
chr6_+_123073408	7.312		Clec4a2	C-type lectin domain family 4, member a2
chr7_+_132695758	7.181	NM_001008700	Il4ra	interleukin 4 receptor, alpha
chr2_-_3339919	7.164	NM_008579	Meig1	meiosis expressed gene 1
chr1_-_53813191	7.046
chr5_+_123465266	6.944		Orai1	ORAI calcium release-activated calcium modulator 1
chr7_+_133920438	6.929	NM_025347 NM_026875	Ypel3	yippee-like 3 (Drosophila)
chr1_+_6720153	6.756		St18	suppression of tumorigenicity 18
chr17_-_51878720	6.752		Satb1	special AT-rich sequence binding protein 1
chr7_-_117987922	6.715		Rnf141	ring finger protein 141
chr17_-_28623006	6.480	NM_010220	Fkbp5	FK506 binding protein 5
chr5_-_88956788	6.410	NM_152839	Igj	immunoglobulin joining chain
chr5_+_138070341	6.398	NM_001168652 NM_146164	Lrch4-sap25 Lrch4	Lrch4-Sap25 gene leucine-rich repeats and calponin homology (CH) domain containing 4
chr5_-_66489416	6.287	NM_139065	Rbm47	RNA binding motif protein 47
chr7_+_26067197	6.197	NM_001110131 NM_001110132 NM_027882	Cic	capicua homolog (Drosophila)
chr13_+_21879356	6.110	NM_178202	Hist1h2bp	histone cluster 1, H2bp
chr12_-_80397239	6.094	NM_001008550	Zfyve26	zinc finger, FYVE domain containing 26
chr4_+_102243272	6.086		Pde4b	phosphodiesterase 4B, cAMP specific
chr4_+_102243132	6.073		Pde4b	phosphodiesterase 4B, cAMP specific
chr1_+_16678513	6.053		Ly96	lymphocyte antigen 96
chr6_-_66987377	6.002	NM_007836	Gadd45a	growth arrest and DNA-damage-inducible 45 alpha
chr7_+_4967081	5.987	NM_025324	Zfp524	zinc finger protein 524
chr7_+_132695735	5.969		Il4ra	interleukin 4 receptor, alpha
chr1_+_6720087	5.876	NM_173868	St18	suppression of tumorigenicity 18
chr9_-_43951401	5.757
chr19_+_12535536	5.586		Mpeg1	macrophage expressed gene 1
chr16_-_17144301	5.437	NM_001164606	Ccdc116	coiled-coil domain containing 116
chr5_+_144951154	5.405	NM_010800	Bhlha15	basic helix-loop-helix family, member a15
chr13_-_54789548	5.351	NM_001146027	Rnf44	ring finger protein 44
chr12_-_36769054	5.297	NM_025359	Tspan13	tetraspanin 13
chr14_+_32973077	5.272	NM_001033988	Ncoa4	nuclear receptor coactivator 4
chr1_+_16678536	5.048	NM_001159711 NM_016923	Ly96	lymphocyte antigen 96
chr2_-_11475555	4.976	NM_001177758	Pfkfb3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr8_+_123059756	4.943	NM_001145897	Gse1	genetic suppressor element 1
chr11_+_98821784	4.782	NM_001176528	Rara	retinoic acid receptor, alpha
chr14_-_68333897	4.770	NM_175384	Cdca2	cell division cycle associated 2
chr10_-_80813198	4.759	NM_001163166	Hmg20b	high mobility group 20 B
chr15_-_66663390	4.753	NM_001029841	Sla	src-like adaptor
chrX_+_7455387	4.738	NM_138606	Pim2	proviral integration site 2
chr5_+_137384005	4.713	NM_026073	Rabl5	RAB, member of RAS oncogene family-like 5
chr6_-_54922563	4.640	NM_172729	Nod1	nucleotide-binding oligomerization domain containing 1
chr2_-_119096952	4.597	NM_145530	Rhov	ras homolog gene family, member V
chr7_+_129432810	4.555		Prkcb	protein kinase C, beta
chr2_-_11475504	4.408		Pfkfb3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr14_-_68333397	4.400		Cdca2	cell division cycle associated 2
chr5_+_117724658	4.344		Taok3	TAO kinase 3
chr12_-_36768992	4.325		Tspan13	tetraspanin 13
chr16_-_17144515	4.280	NM_029779	Ccdc116	coiled-coil domain containing 116
chr14_-_68333666	4.267	NM_001110162	Cdca2	cell division cycle associated 2
chr13_+_16106279	4.255	NM_008380	Inhba	inhibin beta-A
chr5_-_46248719	4.135	NM_001163073 NM_178142	Lcorl	ligand dependent nuclear receptor corepressor-like
chr1_-_93309713	4.101	NM_019479	Hes6	hairy and enhancer of split 6 (Drosophila)
chr2_-_38781939	4.098	NM_010264	Nr6a1	nuclear receptor subfamily 6, group A, member 1
chr18_-_81183260	4.078	NM_178280	Sall3	sal-like 3 (Drosophila)
chr7_+_52273317	4.059	NM_009101	Rras	Harvey rat sarcoma oncogene, subgroup R
chr5_+_73305509	4.048	NM_001113423 NM_153567	Slain2	SLAIN motif family, member 2
chr2_+_155207581	3.895	NM_178111	Trp53inp2	transformation related protein 53 inducible nuclear protein 2
chr16_+_10488270	3.879	NM_007575	Ciita	class II transactivator
chr7_-_117987867	3.660	NM_025999	Rnf141	ring finger protein 141
chr1_-_135586436	3.614	NM_172842 NM_001159649	Lax1	lymphocyte transmembrane adaptor 1
chr1_+_154597680	3.606	NM_001081197	Apobec4	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr7_+_148381017	3.573	NM_153777	Lrrc56	leucine rich repeat containing 56
chr13_-_46060325	3.558	NM_009124	Atxn1	ataxin 1
chr11_+_95198329	3.486	NM_172543	Fam117a	family with sequence similarity 117, memberA
chrX_-_163645313	3.472		Tmsb4x	thymosin, beta 4, X chromosome
chr6_+_115372083	3.468	NM_011146	Pparg	peroxisome proliferator activated receptor gamma
chr7_-_27951724	3.423	NM_053208	Egln2	EGL nine homolog 2 (C. elegans)
chrX_-_137077639	3.421	NM_010286	Tsc22d3	TSC22 domain family, member 3
chr1_-_137155012	3.392	NM_001163131 NM_007921	Elf3	E74-like factor 3
chr4_+_102242664	3.374	NM_001177980	Pde4b	phosphodiesterase 4B, cAMP specific
chr2_+_80171439	3.364		Dnajc10	DnaJ (Hsp40) homolog, subfamily C, member 10
chrX_+_13788273	3.352	NM_001034100	Gm5382	predicted gene 5382
chr15_+_98538624	3.329	NM_153518	Ccdc65	coiled-coil domain containing 65
chr13_-_54789148	3.328	NM_001146025 NM_001146026 NM_134064	Rnf44	ring finger protein 44
chrX_-_76916773	3.323	NM_028025	Mageb16	melanoma antigen family B, 16
chr10_-_90545046	3.269		Apaf1	apoptotic peptidase activating factor 1
chr13_-_21902031	3.268	NM_001097979 NM_001110555	Hist1h2bj Hist1h2bq Hist1h2br	histone cluster 1, H2bj histone cluster 1, H2bq histone cluster 1 H2br
chr4_-_140366562	3.245	NM_011060	Padi3	peptidyl arginine deiminase, type III
chr7_+_52253028	3.216	NM_016849	Irf3	interferon regulatory factor 3
chr2_-_25483461	3.215	NM_007995	Fcna	ficolin A
chr4_-_129374039	3.192	NM_199305	Tmem39b	transmembrane protein 39b
chr5_+_123465011	3.113	NM_175423	Orai1	ORAI calcium release-activated calcium modulator 1
chr12_+_118997623	3.086		Rapgef5	Rap guanine nucleotide exchange factor (GEF) 5
chr13_-_55201655	3.024	NM_011307	Uimc1	ubiquitin interaction motif containing 1
chr10_-_90545406	3.011		Apaf1	apoptotic peptidase activating factor 1
chr17_+_27693821	2.975		Hmga1	high mobility group AT-hook 1
chr7_-_27951432	2.943		Egln2	EGL nine homolog 2 (C. elegans)
chr6_+_67966702	2.922
chr19_-_20802015	2.887	NM_011921	Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7
chr1_-_84741605	2.870		Trip12	thyroid hormone receptor interactor 12
chr13_+_21925611	2.852	NM_001097979 NM_001110555	Hist1h2bj Hist1h2bq Hist1h2br	histone cluster 1, H2bj histone cluster 1, H2bq histone cluster 1 H2br
chr17_+_27693518	2.753	NM_001166476 NM_001166477 NM_001025427 NM_001039356 NM_001166535 NM_001166536 NM_001166539 NM_001166540 NM_001166541 NM_001166542 NM_001166543 NM_001166544 NM_001166545 NM_001166546 NM_001166537 NM_016660	Hmga1-rs1 Hmga1	high mobility group AT-hook I, related sequence 1 high mobility group AT-hook 1
chr2_-_25052245	2.752	NM_146115	A830007P12Rik	RIKEN cDNA A830007P12 gene
chr9_-_44334460	2.672	NM_007551	Cxcr5	chemokine (C-X-C motif) receptor 5
chr2_+_24200807	2.671	NM_001159562	Il1rn	interleukin 1 receptor antagonist
chr7_-_29157512	2.646	NM_001083912 NM_138752	Plekhg2	pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr2_-_103143314	2.645		Ehf	ets homologous factor
chr13_-_55201578	2.636		Uimc1	ubiquitin interaction motif containing 1
chr6_+_136467388	2.605		Atf7ip	activating transcription factor 7 interacting protein
chr4_-_127938134	2.591	NM_027036	Hmgb4	high-mobility group box 4
chr3_+_129883794	2.580	NM_029838 NM_198711	Col25a1	collagen, type XXV, alpha 1
chr9_+_47338449	2.567		Cadm1	cell adhesion molecule 1
chr4_-_151851624	2.559		Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr4_-_151851574	2.486	NM_010598	Kcnab2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chrX_-_9149516	2.476	NM_001085517	Gm5132	predicted gene 5132
chr11_+_121007456	2.449	NM_028602	Tex19.1	testis expressed gene 19.1
chr13_-_108680257	2.435	NM_145456	Zswim6	zinc finger, SWIM domain containing 6
chrX_-_9046362	2.421	NM_007807	Cybb	cytochrome b-245, beta polypeptide
chr11_+_98821723	2.413		Rara	retinoic acid receptor, alpha
chr6_+_125271356	2.400	NM_011324	Scnn1a	sodium channel, nonvoltage-gated 1 alpha
chr6_+_136467315	2.380	NM_019426	Atf7ip	activating transcription factor 7 interacting protein
chr11_-_115353104	2.377	NM_015807	Nt5c	5',3'-nucleotidase, cytosolic
chr13_+_113078658	2.374	NM_001168403 NM_001168405 NM_029898 NM_001168404	Ankrd55	ankyrin repeat domain 55
chrX_+_10889059	2.347	NM_001025260	Gm14484	predicted gene 14484
chr11_-_70468130	2.329	NM_011072	Pfn1	profilin 1
chr11_+_79845841	2.297		Suz12	suppressor of zeste 12 homolog (Drosophila)
chr8_+_34681015	2.285	NM_031374	Tex15	testis expressed gene 15
chr10_-_8605668	2.269	NM_175155	Sash1	SAM and SH3 domain containing 1
chr2_+_24201033	2.257		Il1rn	interleukin 1 receptor antagonist
chr8_-_96059606	2.229	NM_001003951	Ces5a	carboxylesterase 5A
chr11_-_118254729	2.223		Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein
chr1_+_93437120	2.214	NM_001039126	Asb1	ankyrin repeat and SOCS box-containing 1
chr13_-_35118959	2.212
chr2_+_24200925	2.127		Il1rn	interleukin 1 receptor antagonist
chr4_-_128483355	2.117	NM_001081098	Zfp362	zinc finger protein 362
chr7_+_97574821	2.095	NM_027298	Ccdc89	coiled-coil domain containing 89
chrX_+_10885885	2.090	NM_001111037	Gm14483	predicted gene 14483
chr10_-_90545483	2.068	NM_001042558 NM_009684	Apaf1	apoptotic peptidase activating factor 1
chrX_-_49325948	2.047	NM_028851	1700080O16Rik	RIKEN cDNA 1700080O16 gene
chr2_-_103143352	2.026	NM_007914	Ehf	ets homologous factor
chr16_-_92697567	2.018	NM_001111023 NM_009821	Runx1	runt related transcription factor 1
chrX_+_10876382	2.007	NM_001111037	Gm14483	predicted gene 14483
chr17_+_24879324	1.999		Sepx1	selenoprotein X 1
chr6_+_125271727	1.999		Scnn1a	sodium channel, nonvoltage-gated 1 alpha
chr9_-_35597630	1.996	NM_026593	D730048I06Rik	RIKEN cDNA D730048I06 gene
chr5_+_136592559	1.980	NM_011293	Polr2j	polymerase (RNA) II (DNA directed) polypeptide J
chr13_+_4190423	1.968	NM_013778	Akr1c13	aldo-keto reductase family 1, member C13
chrX_+_8927724	1.889	NM_001085537	Gm14501	predicted gene 14501
chr3_-_101091814	1.863	NM_013486	Cd2	CD2 antigen
chrX_+_8860889	1.861	NM_029588	1700012L04Rik	RIKEN cDNA 1700012L04 gene
chr11_+_33947115	1.848	NM_010696	Lcp2	lymphocyte cytosolic protein 2
chr6_-_87483228	1.827	NM_001037727	Arhgap25	Rho GTPase activating protein 25
chr11_+_98562626	1.809	NM_009971	Csf3	colony stimulating factor 3 (granulocyte)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.84	1.80e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.81	2.66e-05	GO:0010556	regulation of macromolecule biosynthetic process
9.27	2.67e-05	GO:0071824	protein-DNA complex subunit organization
1.64	7.38e-05	GO:0031323	regulation of cellular metabolic process
1.75	8.10e-05	GO:0031326	regulation of cellular biosynthetic process
1.84	8.45e-05	GO:0006355	regulation of transcription, DNA-dependent
1.82	9.24e-05	GO:0051252	regulation of RNA metabolic process
1.63	9.82e-05	GO:0080090	regulation of primary metabolic process
1.76	1.13e-04	GO:0010468	regulation of gene expression
1.64	1.22e-04	GO:0060255	regulation of macromolecule metabolic process
1.73	1.44e-04	GO:0009889	regulation of biosynthetic process
9.02	1.54e-04	GO:0034728	nucleosome organization
8.86	1.83e-04	GO:0065004	protein-DNA complex assembly
2.35	3.04e-04	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.71	3.88e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.94	4.04e-04	GO:0006351	transcription, DNA-dependent
8.16	4.11e-04	GO:0006333	chromatin assembly or disassembly
1.93	4.30e-04	GO:0032774	RNA biosynthetic process
1.71	4.88e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
9.25	5.25e-04	GO:0006334	nucleosome assembly
2.35	6.12e-04	GO:0002376	immune system process
8.26	1.43e-03	GO:0031497	chromatin assembly
1.50	3.32e-03	GO:0019222	regulation of metabolic process
5.91	8.51e-03	GO:0006323	DNA packaging
1.63	2.96e-02	GO:0016070	RNA metabolic process
2.31	3.37e-02	GO:0010629	negative regulation of gene expression
5.64	3.56e-02	GO:0042113	B cell activation
1.62	3.62e-02	GO:0048519	negative regulation of biological process
2.04	3.75e-02	GO:0010605	negative regulation of macromolecule metabolic process
1.99	4.11e-02	GO:0009892	negative regulation of metabolic process
2.81	4.16e-02	GO:0006325	chromatin organization

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
16.78	1.02e-13	GO:0000786	nucleosome
10.54	3.15e-10	GO:0032993	protein-DNA complex
1.60	4.24e-08	GO:0005634	nucleus
4.65	5.62e-06	GO:0000785	chromatin
2.76	3.46e-03	GO:0044427	chromosomal part
2.66	3.92e-03	GO:0005694	chromosome
1.25	8.95e-03	GO:0043231	intracellular membrane-bounded organelle
1.25	1.02e-02	GO:0043227	membrane-bounded organelle
1.22	1.71e-02	GO:0043226	organelle
1.21	2.10e-02	GO:0043229	intracellular organelle

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
2.25	7.34e-09	GO:0003677	DNA binding
1.86	1.07e-06	GO:0003676	nucleic acid binding
2.67	1.09e-05	GO:0001071	nucleic acid binding transcription factor activity
2.67	1.09e-05	GO:0003700	sequence-specific DNA binding transcription factor activity
2.46	2.01e-05	GO:0030528	transcription regulator activity
2.36	5.14e-03	GO:0043565	sequence-specific DNA binding
1.20	1.03e-02	GO:0005488	binding