Motif ID: POU5F1.p2

Z-value: 1.586


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
Pou5f1 18999 POU domain, class 5, transcription factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou5f1chr17_+_35642981-0.073.3e-01Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_74150754 42.698 Unc13a
unc-13 homolog A (C. elegans)
chr15_+_91991704 31.967 NM_001159647
 Cntn1
contactin 1
chr8_+_56040080 31.091 NM_153581
 Gpm6a
glycoprotein m6a
chr3_+_13946371 30.204 NM_001163329
NM_001163330
 Ralyl

RALY RNA binding protein-like

chrX_+_162782484 25.949 NM_001177955
NM_001177956
NM_001177957
NM_001177958
NM_001177959
NM_001177960
 Gpm6b





glycoprotein m6b





chr9_-_91255831 25.906 Zic1
zinc finger protein of the cerebellum 1
chr2_-_6466116 23.955 Celf2
CUGBP, Elav-like family member 2
chr10_+_34018323 22.868 Tspyl4
TSPY-like 4
chr12_+_91050912 22.140 Nrxn3
neurexin III
chr3_-_80606500 20.796 Gria2
glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr7_+_129432810 20.003 Prkcb
protein kinase C, beta
chr11_-_69419419 19.659 NM_013415
 Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr8_+_56040445 19.561 Gpm6a
glycoprotein m6a
chr2_-_73497987 19.108 Chn1
chimerin (chimaerin) 1
chr9_-_29770699 18.996 NM_172290
 Ntm
neurotrimin
chr2_-_66278870 18.943 NM_018733
 Scn1a
sodium channel, voltage-gated, type I, alpha
chr8_+_56040193 18.466 Gpm6a
glycoprotein m6a
chr8_+_56040553 18.434 Gpm6a
glycoprotein m6a
chr5_+_135526788 18.325


chr11_-_69419330 18.299 Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 53 entries
Enrichment   P-value GO Accession GO Term
3.36 2.97e-02 GO:0050808 synapse organization
2.35 1.36e-04 GO:0031644 regulation of neurological system process
2.33 6.94e-04 GO:0051969 regulation of transmission of nerve impulse
2.33 1.92e-03 GO:0050804 regulation of synaptic transmission
2.28 7.32e-05 GO:0007268 synaptic transmission
2.28 9.62e-04 GO:0007409 axonogenesis
2.23 7.50e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
2.22 4.33e-04 GO:0048812 neuron projection morphogenesis
2.15 6.55e-04 GO:0045664 regulation of neuron differentiation
2.10 1.60e-04 GO:0031175 neuron projection development
2.09 1.44e-04 GO:0019226 transmission of nerve impulse
2.09 1.44e-04 GO:0035637 multicellular organismal signaling
2.01 4.47e-05 GO:0048666 neuron development
1.99 4.12e-03 GO:0048858 cell projection morphogenesis
1.97 3.14e-03 GO:0050767 regulation of neurogenesis
1.96 7.46e-03 GO:0032990 cell part morphogenesis
1.92 6.99e-04 GO:0007267 cell-cell signaling
1.91 7.88e-05 GO:0030030 cell projection organization
1.91 2.26e-02 GO:0000904 cell morphogenesis involved in differentiation
1.88 2.82e-03 GO:0060284 regulation of cell development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 37 entries
Enrichment   P-value GO Accession GO Term
5.31 2.64e-05 GO:0044304 main axon
3.40 2.34e-05 GO:0014069 postsynaptic density
3.29 1.09e-08 GO:0019717 synaptosome
2.66 2.60e-02 GO:0030427 site of polarized growth
2.59 6.55e-04 GO:0033267 axon part
2.37 3.73e-13 GO:0045202 synapse
2.37 8.81e-09 GO:0044456 synapse part
2.35 1.90e-06 GO:0030424 axon
2.27 2.61e-06 GO:0030425 dendrite
2.27 5.26e-03 GO:0045211 postsynaptic membrane
2.21 3.46e-12 GO:0043005 neuron projection
1.98 1.22e-05 GO:0044463 cell projection part
1.92 8.87e-04 GO:0044297 cell body
1.90 2.08e-03 GO:0043025 neuronal cell body
1.70 4.58e-07 GO:0005626 insoluble fraction
1.69 2.40e-06 GO:0005624 membrane fraction
1.66 8.38e-04 GO:0030054 cell junction
1.64 3.41e-07 GO:0042995 cell projection
1.58 2.42e-06 GO:0000267 cell fraction
1.48 6.50e-03 GO:0044430 cytoskeletal part

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
2.69 1.62e-02 GO:0030165 PDZ domain binding
1.97 5.62e-07 GO:0019904 protein domain specific binding
1.86 3.04e-02 GO:0022836 gated channel activity
1.70 3.10e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.63 2.50e-02 GO:0008092 cytoskeletal protein binding
1.61 3.21e-03 GO:0015075 ion transmembrane transporter activity
1.51 2.01e-02 GO:0022891 substrate-specific transmembrane transporter activity
1.46 3.71e-02 GO:0022857 transmembrane transporter activity
1.35 4.67e-16 GO:0005515 protein binding
1.19 3.15e-15 GO:0005488 binding