Motif ID: POU6F1.p2

Z-value: 0.604


Transcription factors associated with POU6F1.p2:

Gene SymbolEntrez IDGene Name
Pou6f1 19009 POU domain, class 6, transcription factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou6f1chr15_-_100416795-0.001.0e+00Click!


Activity profile for motif POU6F1.p2.

activity profile for motif POU6F1.p2


Sorted Z-values histogram for motif POU6F1.p2

Sorted Z-values for motif POU6F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU6F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_49282546 6.738 NM_144841
Otx2
orthodenticle homolog 2 (Drosophila)
chr15_+_91991704 6.084 NM_001159647
Cntn1
contactin 1
chr1_+_12682572 5.701 Sulf1
sulfatase 1
chr1_+_12682510 5.370 NM_001198565
NM_001198566
Sulf1

sulfatase 1

chr2_-_140485267 5.332 Flrt3
fibronectin leucine rich transmembrane protein 3
chr14_+_28689289 5.206 Erc2
ELKS/RAB6-interacting/CAST family member 2
chr19_+_8665743 4.569 NM_001164634
NM_031194
Slc22a8

solute carrier family 22 (organic anion transporter), member 8

chr18_+_37663917 4.117 NM_053145
Pcdhb20
protocadherin beta 20
chr5_-_87174825 4.105 NM_172880
Tmprss11e
transmembrane protease, serine 11e
chr1_-_65097587 4.031 NM_007777
Cryge
crystallin, gamma E
chr2_-_160773804 3.477 Chd6
chromodomain helicase DNA binding protein 6
chr14_-_104213981 3.218


chr3_-_63654912 2.781 NM_001177732
NM_001177733
NM_183191
Plch1


phospholipase C, eta 1


chr7_+_71330344 2.690 NM_018752
Trpm1
transient receptor potential cation channel, subfamily M, member 1
chr7_+_53172414 2.566


chrX_+_54032858 2.556 NM_001077362
Fhl1
four and a half LIM domains 1
chr18_-_32196584 2.462 NM_032394
Myo7b
myosin VIIB
chr19_-_34736879 2.444 Gm14446
predicted gene 14446
chr8_+_62984911 2.374 NM_011834
Aadat
aminoadipate aminotransferase
chr7_+_53339469 2.309


chr4_-_41516463 2.223 NM_001159583
NM_027993
2310028H24Rik

RIKEN cDNA 2310028H24 gene

chr10_+_69487700 2.202 Ank3
ankyrin 3, epithelial
chr8_+_12984287 2.198 Mcf2l
mcf.2 transforming sequence-like
chrX_+_54032914 2.143 Fhl1
four and a half LIM domains 1
chr11_-_99283568 2.020 NM_010661
Krt12
keratin 12
chr1_+_141398282 1.854 NM_031164
F13b
coagulation factor XIII, beta subunit
chr3_-_115956312 1.837 NM_022427
Gpr88
G-protein coupled receptor 88
chr14_+_55506625 1.796 Bcl2l2
BCL2-like 2
chr1_-_89291303 1.778 NM_001110227
Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr9_-_21820860 1.778 Elavl3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr10_+_69488049 1.764 Ank3
ankyrin 3, epithelial
chr6_-_36761360 1.755 NM_008973
Ptn
pleiotrophin
chr11_+_28767772 1.737 Efemp1
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
chr12_-_82669460 1.728 NM_020330
Adam21
a disintegrin and metallopeptidase domain 21
chr19_+_32694494 1.722 NM_011864
Papss2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr5_-_86947601 1.696 NM_177162
9930032O22Rik
RIKEN cDNA 9930032O22 gene
chr13_-_56649769 1.688 Lect2
leukocyte cell-derived chemotaxin 2
chr4_+_115273542 1.597 NM_001100181
Cyp4a32
cytochrome P450, family 4, subfamily a, polypeptide 32
chr11_+_75007475 1.562 NM_177708
Rtn4rl1
reticulon 4 receptor-like 1
chr18_+_80315134 1.533 Pard6g
par-6 partitioning defective 6 homolog gamma (C. elegans)
chr6_-_122560002 1.514 Gdf3
growth differentiation factor 3
chr5_-_51945054 1.480 NM_008904
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr14_+_103912557 1.454 NM_022886
Scel
sciellin
chr1_-_157589156 1.449 NM_010712
Lhx4
LIM homeobox protein 4
chr11_-_96678887 1.441 Nfe2l1
nuclear factor, erythroid derived 2,-like 1
chr13_-_56649898 1.437 NM_010702
Lect2
leukocyte cell-derived chemotaxin 2
chr1_+_59543450 1.379


chr5_+_27231234 1.375 NM_001198886
Dpp6
dipeptidylpeptidase 6
chr5_-_52957343 1.371 Lgi2
leucine-rich repeat LGI family, member 2
chr4_-_75779379 1.356 NM_001014288
Ptprd
protein tyrosine phosphatase, receptor type, D
chr6_-_130143018 1.345 NM_010651
Klra5
Klra6
Klra9
killer cell lectin-like receptor, subfamily A, member 5
killer cell lectin-like receptor, subfamily A, member 6
killer cell lectin-like receptor subfamily A, member 9
chr12_-_74147683 1.336 Six1
sine oculis-related homeobox 1 homolog (Drosophila)
chr10_+_99823971 1.294 NM_001166638
NM_001166639
NM_001166641
Gm4303
Gm4305
Gm4307
predicted gene 4303
predicted gene 4305
predicted gene 4307
chr10_+_99803471 1.283 NM_001166638
NM_001166639
NM_001166641
Gm4303
Gm4305
Gm4307
predicted gene 4303
predicted gene 4305
predicted gene 4307
chr5_-_71233855 1.274 NM_010252
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr9_-_39066263 1.265 NM_146506
Olfr945
olfactory receptor 945
chr10_+_99813724 1.263 NM_001166634
NM_001166638
NM_001166639
NM_001166641
Gm4302
Gm4303
Gm4305
Gm4307
predicted gene 4302
predicted gene 4303
predicted gene 4305
predicted gene 4307
chr2_-_168559743 1.236 Atp9a
ATPase, class II, type 9A
chr10_+_99808603 1.235 NM_001166634
NM_001166638
NM_001166639
NM_001166641
Gm4302
Gm4303
Gm4305
Gm4307
predicted gene 4302
predicted gene 4303
predicted gene 4305
predicted gene 4307
chr16_+_22892156 1.232 Ahsg
alpha-2-HS-glycoprotein
chr10_-_99845190 1.220 NM_001166637
NM_001166636
Gm4301
Gm4303
Gm4312
predicted gene 4301
predicted gene 4303
predicted gene 4312
chr18_+_37633193 1.203 NM_053140
Pcdhb15
protocadherin beta 15
chr4_+_135979438 1.199 NM_008309
Htr1d
5-hydroxytryptamine (serotonin) receptor 1D
chr17_-_85461840 1.198 Prepl
prolyl endopeptidase-like
chr13_-_56649852 1.196 Lect2
leukocyte cell-derived chemotaxin 2
chr16_+_22892112 1.185 NM_013465
Ahsg
alpha-2-HS-glycoprotein
chrX_-_104035877 1.183 NM_199468
Zcchc5
zinc finger, CCHC domain containing 5
chr3_-_113277601 1.174 NM_007446
Amy1
amylase 1, salivary
chr2_+_181501718 1.145 NM_001171616
NM_008665
Myt1

myelin transcription factor 1

chr10_+_99798309 1.115 NM_001166637
NM_001166636
Gm4301
Gm4312
predicted gene 4301
predicted gene 4312
chr13_+_75227306 1.106 NM_013628
Pcsk1
proprotein convertase subtilisin/kexin type 1
chr2_+_112307393 1.099 2900064A13Rik
RIKEN cDNA 2900064A13 gene
chr6_-_122560022 1.017 NM_008108
Gdf3
growth differentiation factor 3
chr6_-_141895336 1.006 NM_013797
Slco1a1
solute carrier organic anion transporter family, member 1a1
chr12_-_74147698 1.003 NM_009189
Six1
sine oculis-related homeobox 1 homolog (Drosophila)
chr16_+_22892125 1.002 Ahsg
alpha-2-HS-glycoprotein
chr14_+_75642093 0.999 NM_019775
Cpb2
carboxypeptidase B2 (plasma)
chr10_+_99829132 0.998 NM_001166637
NM_001166636
Gm4301
Gm4312
predicted gene 4301
predicted gene 4312
chr11_-_99250663 0.997 NM_010660
Krt10
keratin 10
chr11_-_83343962 0.992 NM_013653
Ccl5
chemokine (C-C motif) ligand 5
chr5_-_143665305 0.977 Actb
actin, beta
chr10_+_127238205 0.965 NM_009040
Rdh16
retinol dehydrogenase 16
chr13_+_43218207 0.962 NM_001005748
Phactr1
phosphatase and actin regulator 1
chr1_+_6720087 0.940 NM_173868
St18
suppression of tumorigenicity 18
chr4_+_115190888 0.922 NM_010011
Cyp4a10
Cyp4a31
cytochrome P450, family 4, subfamily a, polypeptide 10
cytochrome P450, family 4, subfamily a, polypeptide 31
chr12_-_106003060 0.897 Clmn
calmin
chr11_+_92960603 0.881 NM_028296
Car10
carbonic anhydrase 10
chr17_-_33053945 0.847 NM_022434
Cyp4f14
cytochrome P450, family 4, subfamily f, polypeptide 14
chr7_-_93924317 0.840 NM_001159706
NM_016770
Folh1

folate hydrolase

chr11_-_107209443 0.830 Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr11_-_11790403 0.829 NM_016672
Ddc
dopa decarboxylase
chr14_-_100548982 0.824 NM_010636
Klf12
Kruppel-like factor 12
chrX_+_93650774 0.821 NM_001159628
NM_010417
Heph

hephaestin

chr16_+_14705932 0.791 NM_011415
Snai2
snail homolog 2 (Drosophila)
chr4_-_36665923 0.781 NM_001166000
Lingo2
leucine rich repeat and Ig domain containing 2
chr4_+_151712739 0.778 NM_001081376
NM_029216
Chd5

chromodomain helicase DNA binding protein 5

chrX_-_146893563 0.764 NM_001164683
Tmem29
transmembrane protein 29
chr9_-_96233411 0.750 Atp1b3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr8_-_5105158 0.742 NM_011388
Slc10a2
solute carrier family 10, member 2
chr12_-_105282485 0.736 NM_026535
Serpina12
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chr11_+_75007300 0.730 Rtn4rl1
reticulon 4 receptor-like 1
chr3_-_92242684 0.715 NM_009265
Sprr1b
small proline-rich protein 1B
chr2_-_77357674 0.712 NM_001113400
Zfp385b
zinc finger protein 385B
chr19_-_32182638 0.692 Asah2
N-acylsphingosine amidohydrolase 2
chr10_-_28706096 0.688 NM_026336
2310057J18Rik
RIKEN cDNA 2310057J18 gene
chr19_-_39961258 0.684 NM_001104525
Cyp2c69
cytochrome P450, family 2, subfamily c, polypeptide 69
chr10_+_126437764 0.675 NM_009635
Avil
advillin
chr5_-_52957518 0.673 NM_144945
Lgi2
leucine-rich repeat LGI family, member 2
chr8_-_55804030 0.672 NM_028220
Wdr17
WD repeat domain 17
chr6_-_3444484 0.672 NM_178899
Hepacam2
HEPACAM family member 2
chr6_+_57063418 0.671 NM_053231
Vmn1r10
vomeronasal 1 receptor 10
chr16_+_37580303 0.664 Hgd
homogentisate 1, 2-dioxygenase
chr7_-_115210309 0.655 NM_020291
Olfr480
olfactory receptor 480
chr9_+_36651243 0.652 NM_183171
Fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr2_-_164025823 0.643 NM_183271
Wfdc15a
WAP four-disulfide core domain 15A
chr1_+_6720153 0.624 St18
suppression of tumorigenicity 18
chr6_-_13785233 0.618 Gpr85
G protein-coupled receptor 85
chr16_-_58928469 0.616 NM_146999
Olfr181
olfactory receptor 181
chr19_-_40261753 0.614 NM_145499
Cyp2c70
cytochrome P450, family 2, subfamily c, polypeptide 70
chr6_+_29479250 0.614 Irf5
interferon regulatory factor 5
chr2_+_97307652 0.605 NM_178725
Lrrc4c
leucine rich repeat containing 4C
chr7_-_29910144 0.592 NM_009109
Ryr1
ryanodine receptor 1, skeletal muscle
chr12_+_25741653 0.586 Kidins220
kinase D-interacting substrate 220
chr18_-_12914177 0.585 Osbpl1a
oxysterol binding protein-like 1A
chr9_-_73781373 0.583 NM_001081153
Unc13c
unc-13 homolog C (C. elegans)
chr1_+_136186565 0.577 Myog
myogenin
chr1_+_136186579 0.576 NM_031189
Myog
myogenin
chr4_+_41516826 0.571 NM_175138
Dnaic1
dynein, axonemal, intermediate chain 1
chr4_+_42339258 0.567 NM_001100596
NM_001099348
NM_010550
Gm2002
Gm13305
Il11ra2
predicted gene 2002
predicted gene 13305
interleukin 11 receptor, alpha chain 2
chr2_+_162813260 0.567 Sgk2
serum/glucocorticoid regulated kinase 2
chr11_-_60013141 0.563 Srebf1
sterol regulatory element binding transcription factor 1
chr6_-_141895265 0.562 Slco1a1
solute carrier organic anion transporter family, member 1a1
chr15_-_77363703 0.561 NM_175391
Apol7c
apolipoprotein L 7c
chr11_-_50655047 0.560 NM_173387
Zfp879
zinc figer protein 879
chrX_+_106392094 0.548 NM_001037917
Gm6377
predicted gene 6377
chr14_-_79647102 0.546 NM_001033215
Zfp957
zinc finger protein 957
chr9_-_53475591 0.529 Cul5
cullin 5
chr4_-_42039325 0.521 NM_001100596
NM_001099348
NM_010550
Gm2002
Gm13305
Il11ra2
predicted gene 2002
predicted gene 13305
interleukin 11 receptor, alpha chain 2
chr2_-_77008655 0.519 NM_001025576
Ccdc141
coiled-coil domain containing 141
chr3_+_51299646 0.515


chr5_-_107003702 0.512 Gm8350
predicted gene 8350
chr18_-_80443840 0.511 NM_001136181
Hsbp1l1
heat shock factor binding protein 1-like 1
chrX_+_149216463 0.499 NM_010951
Gpr143
G protein-coupled receptor 143
chr3_+_30645214 0.495 NM_029489
Samd7
sterile alpha motif domain containing 7
chr5_-_92682184 0.494 NM_011148
Ppef2
protein phosphatase, EF hand calcium-binding domain 2
chr17_-_24210437 0.492 NM_027008
Kctd5
potassium channel tetramerisation domain containing 5
chr8_-_89996089 0.490 Cbln1
cerebellin 1 precursor protein
chr4_+_43867163 0.490 NM_019473
Olfr155
olfactory receptor 155
chr17_+_17539635 0.486 NM_025681
Lix1
limb expression 1 homolog (chicken)
chr17_-_33054270 0.477 Cyp4f14
cytochrome P450, family 4, subfamily f, polypeptide 14
chrX_-_18038399 0.473 NM_175228
4930578C19Rik
RIKEN cDNA 4930578C19 gene
chr3_+_5090275 0.473


chr5_+_89012600 0.471 Rufy3
RUN and FYVE domain containing 3
chr17_+_37138107 0.471 NM_001168502
Zfp57
zinc finger protein 57
chr11_+_67013553 0.461 NM_030679
Myh1
myosin, heavy polypeptide 1, skeletal muscle, adult
chr12_-_60162382 0.446 NM_030057
Trappc6b
trafficking protein particle complex 6B
chrX_-_108651553 0.431 NM_025949
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr18_+_56591785 0.422 NM_026240
Gramd3
GRAM domain containing 3
chr13_+_18809154 0.416 NM_172120
Vps41
vacuolar protein sorting 41 (yeast)
chr5_-_44162032 0.414 Fbxl5
F-box and leucine-rich repeat protein 5
chr4_+_106260649 0.413 Dhcr24
24-dehydrocholesterol reductase
chr9_-_111592643 0.411 NM_016853
Stac
src homology three (SH3) and cysteine rich domain
chr14_-_125076242 0.408 NM_207667
Fgf14
fibroblast growth factor 14
chr7_+_94732677 0.407 NM_001081414
NM_001143834
Grm5

glutamate receptor, metabotropic 5

chr9_+_54828686 0.404 NM_176844
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr11_-_41996141 0.390 NM_010250
Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr6_+_57354359 0.385 NM_134182
Vmn1r19
vomeronasal 1 receptor 19
chr9_-_53475519 0.383 Cul5
cullin 5
chr4_+_52609145 0.381 NM_026652
4930547C10Rik
RIKEN cDNA 4930547C10 gene
chr3_-_86352170 0.374 NM_011839
Mab21l2
mab-21-like 2 (C. elegans)
chr11_+_67090625 0.367 NM_177369
Myh8
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr2_+_90858663 0.366 Celf1
CUGBP, Elav-like family member 1
chr6_+_41304103 0.360 NM_001038996
Try10
trypsin 10
chr16_+_57152994 0.343 Tomm70a
translocase of outer mitochondrial membrane 70 homolog A (yeast)
chr9_-_58049842 0.340 Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr19_+_4139744 0.328 NM_206973
Gpr152
G protein-coupled receptor 152
chr13_-_54652983 0.324 4833439L19Rik
RIKEN cDNA 4833439L19 gene
chr4_-_19849712 0.322 NM_175406
Atp6v0d2
ATPase, H+ transporting, lysosomal V0 subunit D2
chr7_+_53172153 0.321


chr8_+_15057652 0.320 NM_008664
Myom2
myomesin 2
chr2_+_157740281 0.310 NM_198627
Vstm2l
V-set and transmembrane domain containing 2-like
chr2_+_14096150 0.308 NM_001081310
Fam23a
family with sequence similarity 23, member A
chr6_-_129976943 0.307 NM_008464
NM_053154
Klra6
Klra19
killer cell lectin-like receptor, subfamily A, member 6
killer cell lectin-like receptor, subfamily A, member 19
chr18_+_37501355 0.302 NM_053132
Pcdhb7
protocadherin beta 7
chr5_+_91456489 0.301 NM_053087
Epgn
epithelial mitogen
chr16_-_26526854 0.296 NM_001101640
Tmem207
transmembrane protein 207
chr3_-_91946657 0.295 NM_027042
Lelp1
4930511M18Rik
late cornified envelope-like proline-rich 1
RIKEN cDNA 4930511M18 gene
chr13_-_65307023 0.294 NM_175290
Nlrp4f
NLR family, pyrin domain containing 4F
chr6_+_122503826 0.292 NM_009645
Aicda
activation-induced cytidine deaminase
chr16_-_26755585 0.290


chr4_-_19849637 0.288 Atp6v0d2
ATPase, H+ transporting, lysosomal V0 subunit D2
chr11_-_54674080 0.285 NM_029327
Lyrm7
LYR motif containing 7
chr9_-_53475563 0.284 Cul5
cullin 5
chr2_+_170111212 0.278


chr19_+_56798916 0.278 Adrb1
adrenergic receptor, beta 1
chr18_-_61874531 0.278 Grpel2
GrpE-like 2, mitochondrial
chrX_+_9829439 0.276 NM_008769
Otc
ornithine transcarbamylase
chr18_+_65048630 0.274 Nedd4l
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr10_+_99950922 0.273 NM_146009
Cep290
centrosomal protein 290
chr14_-_120441639 0.271 NM_001001490
Oxgr1
oxoglutarate (alpha-ketoglutarate) receptor 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
4.53 1.90e-02 GO:0008509 anion transmembrane transporter activity
13.78 4.19e-02 GO:0008514 organic anion transmembrane transporter activity