Motif ID: PRDM1.p3

Z-value: 2.358


Transcription factors associated with PRDM1.p3:

Gene SymbolEntrez IDGene Name
Prdm1 12142 PR domain containing 1, with ZNF domain

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prdm1chr10_-_441784740.394.1e-08Click!


Activity profile for motif PRDM1.p3.

activity profile for motif PRDM1.p3


Sorted Z-values histogram for motif PRDM1.p3

Sorted Z-values for motif PRDM1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM1.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_193007202 75.029 NM_007498
 Atf3
activating transcription factor 3
chr9_+_5308846 67.477 NM_007609
 Casp4
caspase 4, apoptosis-related cysteine peptidase
chr3_+_142283605 57.587 NM_010260
 Gbp2
guanylate binding protein 2
chr19_+_34715368 56.882 NM_008331
 Ifit1
interferon-induced protein with tetratricopeptide repeats 1
chr10_+_51210768 56.364 NM_013532
 Lilrb4
leukocyte immunoglobulin-like receptor, subfamily B, member 4
chr7_-_52494453 53.344 Cd37
CD37 antigen
chr1_-_193006986 50.941 Atf3
activating transcription factor 3
chr19_+_29446941 49.737 Cd274
CD274 antigen
chr1_-_174520562 47.778 NM_029084
 Slamf8
SLAM family member 8
chr6_+_145070255 43.876 NM_008511
 Lrmp
lymphoid-restricted membrane protein
chr7_-_52494097 43.043 NM_007645
 Cd37
CD37 antigen
chr8_-_84926440 42.169 NM_008357
 Il15
interleukin 15
chr13_+_74777303 38.606 NM_030711
 Erap1
endoplasmic reticulum aminopeptidase 1
chr2_-_28771940 37.862 NM_019446
NM_001164186
 Barhl1

BarH-like 1 (Drosophila)

chr8_-_125075222 37.116 NM_001037298
 Fam38a
family with sequence similarity 38, member A
chr3_+_106285556 36.984 Dennd2d
DENN/MADD domain containing 2D
chr6_-_39050297 35.828 Parp12
poly (ADP-ribose) polymerase family, member 12
chr1_-_79668530 35.139 NM_183027
 Ap1s3
adaptor-related protein complex AP-1, sigma 3
chr19_-_11124897 32.833 NM_001177351
 AW112010
expressed sequence AW112010
chr11_-_70273434 31.790 Cxcl16
chemokine (C-X-C motif) ligand 16

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 25 entries
Enrichment   P-value GO Accession GO Term
45.14 2.43e-02 GO:0032823 regulation of natural killer cell differentiation
45.14 2.43e-02 GO:0032825 positive regulation of natural killer cell differentiation
24.08 1.67e-02 GO:0071346 cellular response to interferon-gamma
22.57 2.21e-02 GO:0001562 response to protozoan
22.57 2.21e-02 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
22.57 2.21e-02 GO:0042832 defense response to protozoan
21.07 2.74e-05 GO:0034341 response to interferon-gamma
19.01 4.59e-02 GO:0032814 regulation of natural killer cell activation
15.63 4.59e-06 GO:0019882 antigen processing and presentation
6.29 1.36e-03 GO:0045087 innate immune response
5.59 2.36e-08 GO:0006955 immune response
5.38 1.65e-02 GO:0002697 regulation of immune effector process
5.35 4.54e-02 GO:0002696 positive regulation of leukocyte activation
4.67 9.95e-03 GO:0002694 regulation of leukocyte activation
4.48 1.52e-02 GO:0050865 regulation of cell activation
4.22 2.72e-03 GO:0051707 response to other organism
4.08 1.09e-06 GO:0002682 regulation of immune system process
4.02 6.86e-11 GO:0002376 immune system process
4.00 4.61e-02 GO:0019941 modification-dependent protein catabolic process
3.97 4.94e-02 GO:0043632 modification-dependent macromolecule catabolic process

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
19.01 7.86e-03 GO:0005839 proteasome core complex
2.64 6.08e-04 GO:0044421 extracellular region part

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
21.25 5.78e-03 GO:0003950 NAD+ ADP-ribosyltransferase activity
17.20 1.41e-02 GO:0004298 threonine-type endopeptidase activity
17.20 1.41e-02 GO:0070003 threonine-type peptidase activity
4.52 3.35e-02 GO:0005125 cytokine activity
1.43 1.95e-02 GO:0005515 protein binding