Motif ID: PRRX1,2.p2

Z-value: 1.504


Transcription factors associated with PRRX1,2.p2:

Gene SymbolEntrez IDGene Name
Prrx1 18933 paired related homeobox 1
Prrx2 20204 paired related homeobox 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Prrx1chr1_-_165243777-0.231.6e-03Click!
Prrx2chr2_+_30700800-0.214.6e-03Click!


Activity profile for motif PRRX1,2.p2.

activity profile for motif PRRX1,2.p2


Sorted Z-values histogram for motif PRRX1,2.p2

Sorted Z-values for motif PRRX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PRRX1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_146622545 27.166 NM_022881
Rgs18
regulator of G-protein signaling 18
chr14_+_27813547 24.268 NM_010420
Hesx1
homeobox gene expressed in ES cells
chr1_-_140071818 24.121 NM_001111316
NM_011210
Ptprc

protein tyrosine phosphatase, receptor type, C

chr17_-_51878720 22.006 Satb1
special AT-rich sequence binding protein 1
chr6_-_13785233 20.996 Gpr85
G protein-coupled receptor 85
chr1_+_6720153 18.318 St18
suppression of tumorigenicity 18
chr2_-_44965866 18.252 Zeb2
zinc finger E-box binding homeobox 2
chr2_-_7317824 18.032 NM_001110231
Celf2
CUGBP, Elav-like family member 2
chr2_-_73291933 17.722 Wipf1
WAS/WASL interacting protein family, member 1
chr2_-_7317513 17.530 NM_001110232
Celf2
CUGBP, Elav-like family member 2
chr3_+_17695743 17.415 6430547I21Rik
RIKEN cDNA 6430547I21 gene
chr6_-_16848352 17.311 NM_031198
Tcfec
transcription factor EC
chr1_+_6720087 16.877 NM_173868
St18
suppression of tumorigenicity 18
chr10_+_89280918 16.833 Uhrf1bp1l
UHRF1 (ICBP90) binding protein 1-like
chr15_-_66644127 16.348 NM_009192
Sla
src-like adaptor
chr14_-_109313333 15.727 Slitrk1
SLIT and NTRK-like family, member 1
chr1_-_140071630 15.584 Ptprc
protein tyrosine phosphatase, receptor type, C
chr2_-_30952019 15.329 NM_001177650
Fnbp1
formin binding protein 1
chr1_+_97230610 15.124 Fam174a
family with sequence similarity 174, member A
chr2_+_61642509 14.955 NM_009322
Tbr1
T-box brain gene 1
chr1_+_40497472 14.793 NM_001025602
Il1rl1
interleukin 1 receptor-like 1
chr4_-_106812064 14.749 2210012G02Rik
RIKEN cDNA 2210012G02 gene
chr14_-_109313298 14.742 Slitrk1
SLIT and NTRK-like family, member 1
chr6_-_16848314 14.735 Tcfec
transcription factor EC
chr6_+_97941776 14.149 NM_008601
Mitf
microphthalmia-associated transcription factor
chr16_-_75909440 14.090 NM_023380
Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
chr3_+_55586431 13.816 NM_010750
Mab21l1
mab-21-like 1 (C. elegans)
chr12_-_119474010 13.709 Sp4
trans-acting transcription factor 4
chr6_+_30400873 13.249


chr3_+_60432922 12.831 Mbnl1
muscleblind-like 1 (Drosophila)
chrX_+_83115611 12.459 NM_001163539
5430427O19Rik
RIKEN cDNA 5430427O19 gene
chr5_+_90919768 12.284 Afp
alpha fetoprotein
chrX_+_156146532 12.164 NM_021389
Sh3kbp1
SH3-domain kinase binding protein 1
chr14_+_79915429 12.155 Elf1
E74-like factor 1
chr5_+_90919758 12.134 Afp
alpha fetoprotein
chr3_+_136598485 12.034 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr2_-_44968508 11.737 Zeb2
zinc finger E-box binding homeobox 2
chr6_-_136890189 11.530 NM_007486
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr5_+_90919739 11.400 NM_007423
Afp
alpha fetoprotein
chr15_-_66644199 11.275 Sla
src-like adaptor
chr3_+_13946371 11.113 NM_001163329
NM_001163330
Ralyl

RALY RNA binding protein-like

chr1_+_173770709 10.891 NM_013489
Cd84
CD84 antigen
chr10_-_117252126 10.870


chr17_-_90487479 10.755 Nrxn1
neurexin I
chr3_-_78949796 10.714 NM_001099624
Rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr6_+_17616617 10.659 Capza2
capping protein (actin filament) muscle Z-line, alpha 2
chr1_-_167090729 10.456 NM_032005
Tbx19
T-box 19
chr2_-_72931338 10.375


chr13_-_55122556 10.363 Hk3
hexokinase 3
chr13_-_55122654 10.197 Hk3
hexokinase 3
chrX_+_156411885 10.137 Sh3kbp1
SH3-domain kinase binding protein 1
chr5_-_23012407 10.095 Srpk2
serine/arginine-rich protein specific kinase 2
chr13_+_20564928 9.849 NM_198093
Elmo1
engulfment and cell motility 1, ced-12 homolog (C. elegans)
chr13_-_55122670 9.847 NM_001033245
Hk3
hexokinase 3
chr12_+_33535650 9.700 Nampt
nicotinamide phosphoribosyltransferase
chr2_-_44965603 9.571 Zeb2
zinc finger E-box binding homeobox 2
chr7_+_138712015 9.546 Bub3
budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae)
chr1_-_152313294 9.443 NM_001110146
NM_021400
Prg4

proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)

chr11_+_79845841 9.258 Suz12
suppressor of zeste 12 homolog (Drosophila)
chr9_+_7792286 9.224 Tmem123
transmembrane protein 123
chr13_+_97408920 9.220 Col4a3bp
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr15_-_72929166 9.202 2310051F07Rik
RIKEN cDNA 2310051F07 gene
chr10_+_40199817 9.155 Cdk19
cyclin-dependent kinase 19
chr1_-_36330235 9.069 NM_153408
Neurl3
neuralized homolog 3 homolog (Drosophila)
chr4_+_34841027 8.992 NM_009889
Cga
glycoprotein hormones, alpha subunit
chr5_-_52541869 8.867 Dhx15
DEAH (Asp-Glu-Ala-His) box polypeptide 15
chr8_+_68910191 8.848 NM_001166375
March1
membrane-associated ring finger (C3HC4) 1
chr14_-_73762324 8.748 Itm2b
integral membrane protein 2B
chr4_+_19207954 8.693 NM_013927
Cngb3
cyclic nucleotide gated channel beta 3
chr2_-_6466116 8.664 Celf2
CUGBP, Elav-like family member 2
chr6_-_129422702 8.659 NM_020008
Clec7a
C-type lectin domain family 7, member a
chr11_-_94154354 8.613 Luc7l3
LUC7-like 3 (S. cerevisiae)
chr6_-_50604391 8.491 NM_021892
Npvf
neuropeptide VF precursor
chr14_-_109313447 8.489 NM_199065
Slitrk1
SLIT and NTRK-like family, member 1
chr6_-_13789847 8.423 NM_145066
Gpr85
G protein-coupled receptor 85
chr19_-_4287408 8.353 Adrbk1
adrenergic receptor kinase, beta 1
chr3_+_95354031 8.346 Ctss
cathepsin S
chr14_-_34195326 8.320 Mapk8
mitogen-activated protein kinase 8
chr12_+_33987379 8.284 NM_001033436
Atxn7l1
ataxin 7-like 1
chr16_-_89818596 8.254 NM_001145887
Tiam1
T-cell lymphoma invasion and metastasis 1
chr2_-_58012447 8.159 NM_139200
Cytip
cytohesin 1 interacting protein
chr12_+_99506844 8.083 NM_008152
Gpr65
G-protein coupled receptor 65
chr3_+_89586320 8.032 Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chr12_+_87027595 7.944 NM_016767
Batf
basic leucine zipper transcription factor, ATF-like
chr11_-_79056525 7.883 NM_001042565
Wsb1
WD repeat and SOCS box-containing 1
chr3_+_132772586 7.731 Ints12
integrator complex subunit 12
chr11_+_87032504 7.726 Trim37
tripartite motif-containing 37
chr11_-_79337251 7.544 NM_001077496
Evi2b
ecotropic viral integration site 2b
chr3_-_80606500 7.469 Gria2
glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr5_-_65351226 7.402 NM_011604
Tlr6
toll-like receptor 6
chr1_+_19093102 7.382 NM_153154
Tcfap2d
transcription factor AP-2, delta
chr3_+_136598184 7.365 Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr13_-_16115192 7.362 B230303A05Rik
RIKEN cDNA B230303A05 gene
chr9_-_103595136 7.325 Tmem108
transmembrane protein 108
chr7_+_104840013 7.318 Rsf1
remodeling and spacing factor 1
chr5_+_19413335 7.278 NM_001170745
NM_015823
Magi2

membrane associated guanylate kinase, WW and PDZ domain containing 2

chr10_-_31410391 7.257 Nkain2
Na+/K+ transporting ATPase interacting 2
chr1_+_109407998 7.238 NM_001174170
NM_011111
Serpinb2

serine (or cysteine) peptidase inhibitor, clade B, member 2

chr1_-_38014596 7.231 NM_027111
Lyg1
lysozyme G-like 1
chr10_+_98486068 7.223 Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
chr6_+_38868942 7.185 NM_011539
Tbxas1
thromboxane A synthase 1, platelet
chr5_-_100465086 7.169 Hnrpdl
heterogeneous nuclear ribonucleoprotein D-like
chr11_-_76322920 7.127 NM_198018
Abr
active BCR-related gene
chr5_+_106039499 6.961 Lrrc8c
leucine rich repeat containing 8 family, member C
chr7_-_80686630 6.883 NM_001081345
Chd2
chromodomain helicase DNA binding protein 2
chr9_-_112134984 6.829 NM_001177616
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr1_+_152166546 6.823 NM_001159730
NM_024458
Pdc

phosducin

chr6_+_15750966 6.751 Mdfic
MyoD family inhibitor domain containing
chrX_+_156278399 6.726 NM_001135728
Sh3kbp1
SH3-domain kinase binding protein 1
chr16_-_29544883 6.719 NM_001164613
Atp13a4
ATPase type 13A4
chr12_-_11215753 6.646 NM_019544
Msgn1
mesogenin 1
chr11_-_99949426 6.570 NM_001159374
Krt32
keratin 32
chr18_-_6202199 6.533 Kif5b
kinesin family member 5B
chr6_+_134874663 6.531 Cdkn1b
cyclin-dependent kinase inhibitor 1B
chr14_+_120830603 6.523 Mbnl2
muscleblind-like 2
chr15_+_91991704 6.517 NM_001159647
Cntn1
contactin 1
chr14_-_13178341 6.495 NM_080433
Fezf2
Fez family zinc finger 2
chr9_+_94570310 6.491 NM_177909
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr1_-_160286359 6.430 NM_207583
Fam5b
family with sequence similarity 5, member B
chr6_-_129225348 6.419 NM_001033122
Cd69
CD69 antigen
chr9_-_16182674 6.371 NM_001080814
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr9_-_112134930 6.361 Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr16_-_88826362 6.361 NM_013707
Krtap14
keratin associated protein 14
chr14_-_49282546 6.314 NM_144841
Otx2
orthodenticle homolog 2 (Drosophila)
chr13_+_24895094 6.293 BC005537
cDNA sequence BC005537
chr4_+_101180625 6.274 Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr1_+_154654953 6.270 NM_010877
Ncf2
neutrophil cytosolic factor 2
chr4_-_35792385 6.235 NM_001166001
NM_175516
Lingo2

leucine rich repeat and Ig domain containing 2

chr8_-_70342105 6.234 NM_027626
Psd3
pleckstrin and Sec7 domain containing 3
chr16_-_16560240 6.220 NM_139232
NM_139234
Fgd4

FYVE, RhoGEF and PH domain containing 4

chr15_+_18750083 6.135 NM_009865
Cdh10
cadherin 10
chr12_-_88605193 6.134 NM_134044
Vipar
VPS33B interacting protein, apical-basolateral polarity regulator
chr13_+_20182408 6.122 Elmo1
engulfment and cell motility 1, ced-12 homolog (C. elegans)
chr9_+_89094190 6.115 Bcl2a1a
B-cell leukemia/lymphoma 2 related protein A1a
chr12_+_91570569 6.109 Nrxn3
neurexin III
chr6_-_130287518 6.084 NM_010648
Klra3
killer cell lectin-like receptor, subfamily A, member 3
chr17_+_40948047 6.078 NM_011269
Rhag
Rhesus blood group-associated A glycoprotein
chr9_+_118387306 6.011 NM_001164789
NM_010136
Eomes

eomesodermin homolog (Xenopus laevis)

chr10_-_85474581 5.957 NM_177772
Bpil2
bactericidal/permeability-increasing protein-like 2
chr5_-_33590505 5.954


chr14_+_28689289 5.942 Erc2
ELKS/RAB6-interacting/CAST family member 2
chr3_-_15748418 5.924 NM_001173459
LOC100038947
Sirpb1a
signal-regulatory protein beta 1-like
signal-regulatory protein beta 1A
chr6_+_116123984 5.895 Gm8203
predicted pseudogene 8203
chr18_+_35750406 5.881 Matr3
matrin 3
chr3_-_59024076 5.877 P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr2_-_167124096 5.862


chr10_+_32803288 5.799 NM_029726
Trdn
triadin
chr6_+_77192839 5.748 Lrrtm1
leucine rich repeat transmembrane neuronal 1
chr16_+_33500899 5.747 Zfp148
zinc finger protein 148
chr2_-_6805937 5.714 NM_001110228
NM_001160293
NM_010160
Celf2


CUGBP, Elav-like family member 2


chr15_-_42508294 5.712 NM_009640
Angpt1
angiopoietin 1
chr17_+_71168939 5.699 Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr12_+_110798661 5.666 Meg3
maternally expressed 3
chr7_-_128217980 5.645 NM_030691
Igsf6
immunoglobulin superfamily, member 6
chr8_-_40727989 5.639 NM_001113326
NM_031195
Msr1

macrophage scavenger receptor 1

chr8_-_8666771 5.633 Arglu1
arginine and glutamate rich 1
chr11_+_46254601 5.621 Med7
mediator complex subunit 7
chr10_-_124765435 5.607 NM_011391
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr8_+_123651742 5.606 Foxl1
forkhead box L1
chr3_+_94968227 5.600 NM_011351
Sema6c
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
chr9_-_112090150 5.598 NM_033264
NM_001177615
NM_001177620
NM_028755
Arpp21



cyclic AMP-regulated phosphoprotein, 21



chr10_+_67000613 5.597 NM_010118
Egr2
early growth response 2
chr11_+_33946927 5.587 Lcp2
lymphocyte cytosolic protein 2
chr2_-_44968728 5.577 NM_015753
Zeb2
zinc finger E-box binding homeobox 2
chr14_-_122314994 5.540 NM_182806
Gpr18
G protein-coupled receptor 18
chr1_+_40572206 5.537 NM_010553
Il18rap
interleukin 18 receptor accessory protein
chr6_-_138028436 5.535 NM_177787
Slc15a5
solute carrier family 15, member 5
chr16_+_7069971 5.520 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr3_+_94217197 5.495 NM_028307
Tdrkh
tudor and KH domain containing protein
chr2_-_37225800 5.493 Rc3h2
ring finger and CCCH-type zinc finger domains 2
chr16_-_19983049 5.461 NM_183390
Klhl6
kelch-like 6 (Drosophila)
chr9_-_88626434 5.428 Bcl2a1d
B-cell leukemia/lymphoma 2 related protein A1d
chr3_+_84470230 5.415 Tmem154
transmembrane protein 154
chr19_+_12873115 5.413 Lpxn
leupaxin
chrX_-_135619753 5.375 NM_177920
Serpina7
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr11_-_51414445 5.328


chr17_-_33783578 5.323 Hnrnpm
heterogeneous nuclear ribonucleoprotein M
chr18_+_63158808 5.310 Napg
N-ethylmaleimide sensitive fusion protein attachment protein gamma
chr3_-_115956312 5.308 NM_022427
Gpr88
G-protein coupled receptor 88
chr14_-_118450875 5.303 NM_010024
Dct
dopachrome tautomerase
chr3_+_17954689 5.221 Bhlhe22
basic helix-loop-helix family, member e22
chr19_+_21354915 5.219 Zfand5
zinc finger, AN1-type domain 5
chr1_+_40082201 5.205 Map4k4
mitogen-activated protein kinase kinase kinase kinase 4
chr7_-_53922712 5.200 NM_001136084
Tph1
tryptophan hydroxylase 1
chr14_+_75576599 5.171 Lcp1
lymphocyte cytosolic protein 1
chr4_-_19849637 5.158 Atp6v0d2
ATPase, H+ transporting, lysosomal V0 subunit D2
chr9_-_91255831 5.151 Zic1
zinc finger protein of the cerebellum 1
chr5_+_138628733 5.135 NM_178612
Cnpy4
canopy 4 homolog (zebrafish)
chrX_+_45499599 5.126 NM_028773
Sash3
SAM and SH3 domain containing 3
chr9_-_96371668 5.119 Rnf7
ring finger protein 7
chr1_-_127289729 5.089


chr9_-_119977358 5.087 NM_009987
Cx3cr1
chemokine (C-X3-C) receptor 1
chr8_-_3625251 5.061 NM_008790
Pcp2
Purkinje cell protein 2 (L7)
chr9_-_96632093 4.997 NM_175537
Zbtb38
zinc finger and BTB domain containing 38
chr18_+_54113094 4.976 Csnk1g3
casein kinase 1, gamma 3
chr7_+_98239230 4.959 NM_011807
Dlg2
discs, large homolog 2 (Drosophila)
chr4_-_136891931 4.957 Cdc42
cell division cycle 42 homolog (S. cerevisiae)
chr13_+_83803830 4.910 Mef2c
myocyte enhancer factor 2C
chr16_-_97392319 4.885 NM_031174
Dscam
Down syndrome cell adhesion molecule
chr6_-_136889984 4.877 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.49 5.60e-15 GO:0048731 system development
1.44 2.54e-13 GO:0048856 anatomical structure development
1.37 4.12e-13 GO:0060255 regulation of macromolecule metabolic process
1.46 9.28e-13 GO:0051252 regulation of RNA metabolic process
1.44 1.37e-12 GO:0010556 regulation of macromolecule biosynthetic process
1.46 2.30e-12 GO:0006355 regulation of transcription, DNA-dependent
1.43 4.94e-12 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.41 6.94e-12 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35 6.96e-12 GO:0080090 regulation of primary metabolic process
1.49 8.19e-12 GO:0048869 cellular developmental process
1.50 1.35e-11 GO:0030154 cell differentiation
1.40 1.59e-11 GO:0051171 regulation of nitrogen compound metabolic process
1.40 1.74e-11 GO:0009889 regulation of biosynthetic process
1.37 1.80e-11 GO:0032502 developmental process
1.34 2.80e-11 GO:0031323 regulation of cellular metabolic process
1.38 3.11e-11 GO:0007275 multicellular organismal development
1.52 3.29e-11 GO:0048513 organ development
1.40 3.39e-11 GO:0031326 regulation of cellular biosynthetic process
1.40 6.53e-11 GO:0010468 regulation of gene expression
1.51 1.04e-10 GO:0032774 RNA biosynthetic process
1.51 1.42e-10 GO:0006351 transcription, DNA-dependent
1.31 1.55e-10 GO:0019222 regulation of metabolic process
1.40 6.37e-09 GO:0016070 RNA metabolic process
1.36 2.83e-08 GO:0010467 gene expression
1.24 9.69e-08 GO:0044260 cellular macromolecule metabolic process
1.34 1.36e-07 GO:0090304 nucleic acid metabolic process
1.55 1.82e-07 GO:0007399 nervous system development
1.30 2.56e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22 3.99e-07 GO:0043170 macromolecule metabolic process
1.68 4.50e-07 GO:0048699 generation of neurons
1.82 5.23e-07 GO:0030182 neuron differentiation
1.46 1.12e-06 GO:0051239 regulation of multicellular organismal process
1.27 1.43e-06 GO:0006807 nitrogen compound metabolic process
1.27 1.58e-06 GO:0034641 cellular nitrogen compound metabolic process
1.34 1.61e-06 GO:0048522 positive regulation of cellular process
1.34 1.94e-06 GO:0009059 macromolecule biosynthetic process
1.63 2.25e-06 GO:0022008 neurogenesis
1.34 2.42e-06 GO:0048519 negative regulation of biological process
1.34 3.40e-06 GO:0034645 cellular macromolecule biosynthetic process
1.60 3.53e-06 GO:2000026 regulation of multicellular organismal development
1.30 6.08e-06 GO:0048518 positive regulation of biological process
1.45 1.34e-05 GO:0009653 anatomical structure morphogenesis
1.54 1.55e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.20 1.82e-05 GO:0007409 axonogenesis
2.11 3.89e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.50 4.72e-05 GO:0050793 regulation of developmental process
1.32 9.05e-05 GO:0048523 negative regulation of cellular process
1.80 9.27e-05 GO:0048666 neuron development
1.26 9.40e-05 GO:0044249 cellular biosynthetic process
1.26 1.09e-04 GO:0009058 biosynthetic process
1.41 1.32e-04 GO:0009893 positive regulation of metabolic process
1.50 1.52e-04 GO:0009891 positive regulation of biosynthetic process
1.92 2.03e-04 GO:0048858 cell projection morphogenesis
1.91 2.04e-04 GO:0032990 cell part morphogenesis
2.52 2.04e-04 GO:0050670 regulation of lymphocyte proliferation
2.02 2.27e-04 GO:0048812 neuron projection morphogenesis
1.42 2.38e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.75 2.51e-04 GO:0007417 central nervous system development
2.50 2.58e-04 GO:0032944 regulation of mononuclear cell proliferation
2.85 2.64e-04 GO:0050671 positive regulation of lymphocyte proliferation
1.51 2.75e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.49 3.07e-04 GO:0031328 positive regulation of cellular biosynthetic process
2.82 3.53e-04 GO:0032946 positive regulation of mononuclear cell proliferation
2.46 4.07e-04 GO:0070663 regulation of leukocyte proliferation
3.29 5.72e-04 GO:0042102 positive regulation of T cell proliferation
2.76 6.21e-04 GO:0070665 positive regulation of leukocyte proliferation
1.40 6.42e-04 GO:0031325 positive regulation of cellular metabolic process
1.50 9.04e-04 GO:0048468 cell development
1.84 9.78e-04 GO:0031175 neuron projection development
1.08 1.15e-03 GO:0009987 cellular process
1.51 2.26e-03 GO:0045595 regulation of cell differentiation
1.83 2.46e-03 GO:0000904 cell morphogenesis involved in differentiation
1.64 3.00e-03 GO:0030030 cell projection organization
2.66 3.70e-03 GO:0042129 regulation of T cell proliferation
2.51 3.76e-03 GO:0021953 central nervous system neuron differentiation
1.68 3.89e-03 GO:0000902 cell morphogenesis
1.46 3.92e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14 4.87e-03 GO:0044238 primary metabolic process
1.45 6.39e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.12 6.49e-03 GO:0050794 regulation of cellular process
1.48 7.19e-03 GO:0051254 positive regulation of RNA metabolic process
1.14 8.06e-03 GO:0044237 cellular metabolic process
2.27 9.01e-03 GO:0010638 positive regulation of organelle organization
1.11 9.47e-03 GO:0050789 regulation of biological process
1.58 9.70e-03 GO:0051094 positive regulation of developmental process
1.11 9.79e-03 GO:0065007 biological regulation
2.05 1.19e-02 GO:0045165 cell fate commitment
2.56 1.28e-02 GO:0030217 T cell differentiation
1.47 1.44e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.50 1.50e-02 GO:0010629 negative regulation of gene expression
1.45 1.72e-02 GO:0010628 positive regulation of gene expression
1.60 2.05e-02 GO:0032989 cellular component morphogenesis
1.90 2.16e-02 GO:0030900 forebrain development
2.09 2.19e-02 GO:0002696 positive regulation of leukocyte activation
2.06 2.31e-02 GO:0050867 positive regulation of cell activation
2.14 2.99e-02 GO:0042110 T cell activation
1.79 3.32e-02 GO:0045321 leukocyte activation
1.70 3.40e-02 GO:0048534 hemopoietic or lymphoid organ development
1.41 3.67e-02 GO:0042127 regulation of cell proliferation
1.72 3.93e-02 GO:0001775 cell activation
1.38 3.97e-02 GO:0032879 regulation of localization
1.45 4.00e-02 GO:0051049 regulation of transport
1.74 4.20e-02 GO:0033043 regulation of organelle organization
1.87 4.20e-02 GO:0046649 lymphocyte activation
1.60 4.65e-02 GO:0060341 regulation of cellular localization
2.09 4.97e-02 GO:0051251 positive regulation of lymphocyte activation

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.13 1.17e-10 GO:0005622 intracellular
1.13 1.76e-09 GO:0044424 intracellular part
1.24 1.97e-09 GO:0005634 nucleus
1.08 2.35e-08 GO:0005623 cell
1.08 2.35e-08 GO:0044464 cell part
1.14 8.94e-08 GO:0043226 organelle
1.14 1.54e-07 GO:0043229 intracellular organelle
1.13 1.79e-05 GO:0043227 membrane-bounded organelle
1.23 2.15e-05 GO:0071944 cell periphery
1.13 2.93e-05 GO:0043231 intracellular membrane-bounded organelle
2.28 2.93e-05 GO:0045111 intermediate filament cytoskeleton
2.42 4.12e-05 GO:0005882 intermediate filament
1.22 6.36e-05 GO:0005886 plasma membrane
1.63 7.95e-05 GO:0043005 neuron projection
1.95 9.67e-04 GO:0009897 external side of plasma membrane
1.23 1.12e-03 GO:0043234 protein complex
1.29 1.60e-03 GO:0044459 plasma membrane part
1.80 3.54e-03 GO:0030424 axon
2.03 5.02e-03 GO:0045211 postsynaptic membrane
1.36 6.36e-03 GO:0042995 cell projection
1.54 9.44e-03 GO:0045202 synapse
1.19 1.20e-02 GO:0032991 macromolecular complex
1.41 2.11e-02 GO:0031982 vesicle
1.15 2.90e-02 GO:0044422 organelle part
1.15 3.93e-02 GO:0044446 intracellular organelle part
1.47 3.98e-02 GO:0031988 membrane-bounded vesicle

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.15 1.99e-13 GO:0005488 binding
1.78 6.08e-13 GO:0030528 transcription regulator activity
1.24 1.55e-10 GO:0005515 protein binding
1.65 5.87e-07 GO:0001071 nucleic acid binding transcription factor activity
1.65 5.87e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.38 3.49e-06 GO:0003677 DNA binding
1.64 1.18e-05 GO:0043565 sequence-specific DNA binding
1.28 3.72e-05 GO:0003676 nucleic acid binding
1.77 8.95e-04 GO:0016563 transcription activator activity
1.76 2.22e-03 GO:0016564 transcription repressor activity
1.32 1.01e-02 GO:0008270 zinc ion binding
1.71 2.42e-02 GO:0046982 protein heterodimerization activity
1.18 3.51e-02 GO:0046872 metal ion binding
1.27 3.83e-02 GO:0046914 transition metal ion binding
4.43 3.96e-02 GO:0030291 protein serine/threonine kinase inhibitor activity
3.29 4.53e-02 GO:0035586 purinergic receptor activity
3.98 4.83e-02 GO:0001608 nucleotide receptor activity, G-protein coupled
3.98 4.83e-02 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled
3.46 4.94e-02 GO:0001614 purinergic nucleotide receptor activity
3.46 4.94e-02 GO:0016502 nucleotide receptor activity