Motif ID: RFX1..5_RFXANK_RFXAP.p2

Z-value: 5.544


Transcription factors associated with RFX1..5_RFXANK_RFXAP.p2:

Gene SymbolEntrez IDGene Name
Rfx1 19724 regulatory factor X, 1 (influences HLA class II expression)
Rfx2 19725 regulatory factor X, 2 (influences HLA class II expression)
Rfx3 19726 regulatory factor X, 3 (influences HLA class II expression)
Rfx4 71137 regulatory factor X, 4 (influences HLA class II expression)
Rfx5 53970 regulatory factor X, 5 (influences HLA class II expression)
Rfxank 19727 regulatory factor X-associated ankyrin-containing protein
Rfxap 170767 regulatory factor X-associated protein

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rfx4chr10_+_842187920.754.0e-34Click!
Rfx3chr19_-_280855340.643.1e-22Click!
Rfxankchr8_-_72662994-0.365.1e-07Click!
Rfxapchr3_-_546116630.296.6e-05Click!
Rfx1chr8_+_865907180.241.3e-03Click!
Rfx2chr17_-_569703320.191.1e-02Click!
Rfx5chr3_+_94758056,
chr3_+_94758936
-0.018.6e-01Click!


Activity profile for motif RFX1..5_RFXANK_RFXAP.p2.

activity profile for motif RFX1..5_RFXANK_RFXAP.p2


Sorted Z-values histogram for motif RFX1..5_RFXANK_RFXAP.p2

Sorted Z-values for motif RFX1..5_RFXANK_RFXAP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RFX1..5_RFXANK_RFXAP.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_7496899 182.767 NM_013892
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr9_-_60535699 150.267 Lrrc49
leucine rich repeat containing 49
chr10_+_34017221 99.331 NM_030203
Tspyl4
TSPY-like 4
chr12_-_73509668 87.579 Rtn1
reticulon 1
chr12_-_73509537 87.042 Rtn1
reticulon 1
chr14_-_9142289 86.656 NM_183187
Fam107a
family with sequence similarity 107, member A
chr11_-_70846926 78.512 6330403K07Rik
RIKEN cDNA 6330403K07 gene
chr4_+_122860705 73.543 NM_174998
Hpcal4
hippocalcin-like 4
chr11_-_70847078 71.999 NM_134022
6330403K07Rik
RIKEN cDNA 6330403K07 gene
chr9_-_60535841 70.860 NM_001146046
NM_145616
Lrrc49

leucine rich repeat containing 49

chrX_+_133527693 70.541 NM_001035509
NM_001035510
NM_025893
Zcchc18


zinc finger, CCHC domain containing 18


chr5_+_31117077 68.075 NM_133350
Mapre3
microtubule-associated protein, RP/EB family, member 3
chr17_+_27822162 68.048 NM_178365
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr10_+_74500008 67.746 Rab36
RAB36, member RAS oncogene family
chr17_+_46390828 66.941 NM_001111142
Gm88
predicted gene 88
chr7_+_17530050 61.493 Pnmal2
PNMA-like 2
chr3_+_82162091 60.630 Mtap9
microtubule-associated protein 9
chr7_+_17529961 60.338 NM_001099636
Pnmal2
PNMA-like 2
chrX_+_33735898 58.016 NM_028325
Zcchc12
zinc finger, CCHC domain containing 12
chr18_-_43847367 57.453 NM_001163637
Jakmip2
janus kinase and microtubule interacting protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
9.54 1.38e-08 GO:0042384 cilium assembly
8.26 8.66e-09 GO:0060271 cilium morphogenesis
5.40 1.32e-05 GO:0010927 cellular component assembly involved in morphogenesis
4.51 9.76e-05 GO:0030031 cell projection assembly
2.44 3.38e-02 GO:0007283 spermatogenesis
2.44 3.38e-02 GO:0048232 male gamete generation
1.35 5.12e-13 GO:0008150 biological_process

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
Enrichment   P-value GO Accession GO Term
12.40 4.09e-02 GO:0034464 BBSome
9.92 3.91e-03 GO:0035085 cilium axoneme
8.00 5.58e-05 GO:0005930 axoneme
7.97 8.34e-10 GO:0019861 flagellum
7.44 4.55e-04 GO:0044441 cilium part
6.43 1.87e-02 GO:0005932 microtubule basal body
6.43 1.87e-02 GO:0009434 microtubule-based flagellum
5.99 6.37e-19 GO:0005929 cilium
3.29 1.54e-07 GO:0005874 microtubule
2.60 7.18e-09 GO:0015630 microtubule cytoskeleton
2.30 4.45e-04 GO:0044463 cell projection part
2.15 1.01e-09 GO:0042995 cell projection
1.73 5.19e-03 GO:0044430 cytoskeletal part
1.69 7.22e-05 GO:0005856 cytoskeleton
1.32 1.87e-09 GO:0005575 cellular_component

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
8.26 1.68e-02 GO:0051018 protein kinase A binding
1.28 1.50e-09 GO:0003674 molecular_function