Motif ID: RREB1.p2

Z-value: 1.383


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
Rreb1 68750 ras responsive element binding protein 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rreb1chr13_+_37918780,
chr13_+_37919261,
chr13_+_37917906		-0.431.0e-09Click!


Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_110783593 24.228 Meg3
maternally expressed 3
chr7_-_31838140 21.233 Fxyd1
FXYD domain-containing ion transport regulator 1
chr9_+_36640268 18.884 Fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr12_+_110783786 18.042 Meg3
maternally expressed 3
chr18_-_33623069 17.801 NM_001109990
 D0H4S114
DNA segment, human D4S114
chr18_-_33623668 17.497 NM_001109988
 D0H4S114
DNA segment, human D4S114
chr18_-_33623400 15.653 NM_001109989
 D0H4S114
DNA segment, human D4S114
chr4_-_150482562 14.539 Camta1
calmodulin binding transcription activator 1
chr1_-_125942073 13.597 NM_199021
 Dpp10
dipeptidylpeptidase 10
chr13_-_78337844 13.192 Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr11_-_59263437 12.869 NM_144521
 Snap47
synaptosomal-associated protein, 47
chr18_-_33623287 12.774 NM_053078
 D0H4S114
DNA segment, human D4S114
chr2_+_92439758 12.443 NM_023850
 Chst1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr6_+_88775664 12.279 Mgll
monoglyceride lipase
chr17_+_37210011 11.764 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_-_70847078 11.666 NM_134022
 6330403K07Rik
RIKEN cDNA 6330403K07 gene
chr12_+_110782654 11.323 Meg3
maternally expressed 3
chr4_-_82150687 11.213 Nfib
nuclear factor I/B
chr11_-_70846926 11.002 6330403K07Rik
RIKEN cDNA 6330403K07 gene
chr3_-_84063605 10.963 Trim2
tripartite motif-containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 160 entries
Enrichment   P-value GO Accession GO Term
6.05 3.37e-02 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway
3.84 2.78e-03 GO:0051966 regulation of synaptic transmission, glutamatergic
3.66 5.76e-04 GO:0046928 regulation of neurotransmitter secretion
3.27 4.91e-03 GO:0051588 regulation of neurotransmitter transport
2.98 1.42e-02 GO:0007270 nerve-nerve synaptic transmission
2.96 2.89e-02 GO:0021549 cerebellum development
2.53 3.35e-06 GO:0003012 muscle system process
2.50 2.14e-02 GO:0032409 regulation of transporter activity
2.45 1.67e-04 GO:0006936 muscle contraction
2.39 7.84e-04 GO:0031346 positive regulation of cell projection organization
2.33 2.09e-02 GO:0050770 regulation of axonogenesis
2.28 3.22e-06 GO:0042391 regulation of membrane potential
2.27 6.06e-08 GO:0051969 regulation of transmission of nerve impulse
2.27 3.52e-07 GO:0050804 regulation of synaptic transmission
2.25 4.45e-02 GO:0031589 cell-substrate adhesion
2.24 9.52e-06 GO:0010975 regulation of neuron projection development
2.24 1.25e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.24 1.25e-04 GO:0022604 regulation of cell morphogenesis
2.23 5.12e-07 GO:0031344 regulation of cell projection organization
2.23 3.97e-02 GO:0034765 regulation of ion transmembrane transport

Gene overrepresentation in compartment category:

Showing 1 to 20 of 83 entries
Enrichment   P-value GO Accession GO Term
5.32 3.98e-04 GO:0005583 fibrillar collagen
3.62 2.63e-02 GO:0034704 calcium channel complex
3.57 1.36e-03 GO:0030672 synaptic vesicle membrane
3.45 1.25e-04 GO:0043198 dendritic shaft
3.34 3.95e-03 GO:0044304 main axon
3.00 1.01e-03 GO:0043195 terminal button
2.95 1.61e-06 GO:0044309 neuron spine
2.94 8.62e-03 GO:0042734 presynaptic membrane
2.89 2.64e-10 GO:0044420 extracellular matrix part
2.84 1.42e-05 GO:0043197 dendritic spine
2.82 3.76e-06 GO:0005604 basement membrane
2.82 3.76e-06 GO:0030426 growth cone
2.80 2.73e-06 GO:0030427 site of polarized growth
2.77 2.30e-10 GO:0033267 axon part
2.76 1.87e-21 GO:0030424 axon
2.66 8.33e-05 GO:0043679 axon terminus
2.62 4.78e-03 GO:0005901 caveola
2.58 1.13e-04 GO:0042383 sarcolemma
2.57 5.58e-19 GO:0030425 dendrite
2.55 1.55e-04 GO:0044306 neuron projection terminus

Gene overrepresentation in function category:

Showing 1 to 20 of 51 entries
Enrichment   P-value GO Accession GO Term
6.91 8.61e-03 GO:0008113 peptide-methionine-(S)-S-oxide reductase activity
5.18 3.76e-03 GO:0005159 insulin-like growth factor receptor binding
4.61 6.15e-04 GO:0004683 calmodulin-dependent protein kinase activity
3.34 1.46e-02 GO:0005201 extracellular matrix structural constituent
2.87 2.52e-10 GO:0005516 calmodulin binding
2.69 4.51e-09 GO:0022843 voltage-gated cation channel activity
2.69 9.99e-06 GO:0005249 voltage-gated potassium channel activity
2.46 5.21e-03 GO:0019199 transmembrane receptor protein kinase activity
2.46 4.10e-02 GO:0004714 transmembrane receptor protein tyrosine kinase activity
2.40 1.31e-05 GO:0005267 potassium channel activity
2.37 2.65e-04 GO:0019838 growth factor binding
2.30 1.23e-07 GO:0005244 voltage-gated ion channel activity
2.30 1.23e-07 GO:0022832 voltage-gated channel activity
2.18 5.77e-05 GO:0001871 pattern binding
2.18 5.77e-05 GO:0030247 polysaccharide binding
2.18 2.65e-04 GO:0005539 glycosaminoglycan binding
2.10 2.78e-02 GO:0008201 heparin binding
2.06 2.73e-08 GO:0022836 gated channel activity
2.03 1.99e-08 GO:0003779 actin binding
1.94 9.75e-13 GO:0008092 cytoskeletal protein binding