Motif ID: RUNX1..3.p2

Z-value: 3.019


Transcription factors associated with RUNX1..3.p2:

Gene SymbolEntrez IDGene Name
Runx1 12394 runt related transcription factor 1
Runx2 12393 runt related transcription factor 2
Runx3 12399 runt related transcription factor 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Runx1chr16_-_928263070.815.0e-44Click!
Runx3chr4_+_1346765590.722.0e-30Click!
Runx2chr17_-_44951745,
chr17_-_44873596
0.467.7e-11Click!


Activity profile for motif RUNX1..3.p2.

activity profile for motif RUNX1..3.p2


Sorted Z-values histogram for motif RUNX1..3.p2

Sorted Z-values for motif RUNX1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RUNX1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_103664214 86.993 NM_008979
Ptpn22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr16_-_92826307 85.281 NM_001111021
NM_001111022
Runx1

runt related transcription factor 1

chr11_-_79337178 77.643 Evi2b
ecotropic viral integration site 2b
chr1_-_146096156 69.422 NM_015811
Rgs1
regulator of G-protein signaling 1
chr1_-_140071818 68.324 NM_001111316
NM_011210
Ptprc

protein tyrosine phosphatase, receptor type, C

chr16_-_92826239 65.739 Runx1
runt related transcription factor 1
chr4_+_134676559 65.635 NM_019732
Runx3
runt related transcription factor 3
chr19_+_12873063 62.262 NM_134152
Lpxn
leupaxin
chr19_+_12873115 61.537 Lpxn
leupaxin
chr4_-_143571878 55.480 3930401B19Rik
RIKEN cDNA 3930401B19 gene
chr11_-_79337251 54.250 NM_001077496
Evi2b
ecotropic viral integration site 2b
chr2_-_58012447 52.050 NM_139200
Cytip
cytohesin 1 interacting protein
chr11_-_83462722 48.654 NM_011337
Ccl3
chemokine (C-C motif) ligand 3
chr19_-_20465115 47.543 Anxa1
annexin A1
chr17_-_44951745 45.086 NM_001146038
NM_009820
Runx2

runt related transcription factor 2

chr7_+_51827801 44.337 NM_008437
Napsa
napsin A aspartic peptidase
chr1_-_140071630 44.221 Ptprc
protein tyrosine phosphatase, receptor type, C
chr5_-_65324796 43.712 Tlr1
toll-like receptor 1
chr3_-_135271247 43.686 Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
chr15_-_9459496 43.420 Il7r
interleukin 7 receptor
chr15_-_9459612 43.062 NM_008372
Il7r
interleukin 7 receptor
chr8_+_90806890 42.231 NM_001109756
Adcy7
adenylate cyclase 7
chr3_-_135271190 42.060 Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
chr1_-_133096633 42.007 Rassf5
Ras association (RalGDS/AF-6) domain family member 5
chrX_-_7667574 40.781 NM_009515
Was
Wiskott-Aldrich syndrome homolog (human)
chr11_+_82878590 40.558 NM_011408
Slfn2
schlafen 2
chr10_-_61970481 40.356 NM_011157
Srgn
serglycin
chr2_-_34813633 39.167 Traf1
TNF receptor-associated factor 1
chr10_+_79457716 37.695 Cnn2
calponin 2
chrX_+_104344953 37.273 NM_175442
A630033H20Rik
RIKEN cDNA A630033H20 gene
chr2_-_34813680 36.924 Traf1
TNF receptor-associated factor 1
chr7_+_133728451 35.908 Apobr
apolipoprotein B receptor
chr2_+_150396150 35.846 NM_009977
Cst7
cystatin F (leukocystatin)
chr7_-_133848235 35.002 NM_009898
Coro1a
coronin, actin binding protein 1A
chr3_-_58905678 34.846 NM_173398
Gpr171
G protein-coupled receptor 171
chrX_-_54591905 33.799 NM_152801
Arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr5_-_138312923 32.689 NM_001024932
Pilrb2
paired immunoglobin-like type 2 receptor beta 2
chr15_-_78403110 32.443 NM_009008
Rac2
RAS-related C3 botulinum substrate 2
chr17_+_29629987 32.118 Pim1
proviral integration site 1
chr14_+_75576599 32.072 Lcp1
lymphocyte cytosolic protein 1
chr3_-_94946256 31.377 NM_027206
Tnfaip8l2
tumor necrosis factor, alpha-induced protein 8-like 2
chr1_-_133176085 30.851 NM_019777
Ikbke
inhibitor of kappaB kinase epsilon
chr7_-_50788445 30.563 Cd33
CD33 antigen
chr11_-_79343891 30.294 Evi2a
ecotropic viral integration site 2a
chr7_+_129432585 29.930 NM_008855
Prkcb
protein kinase C, beta
chr19_-_20465158 29.783 NM_010730
Anxa1
annexin A1
chrX_+_104451216 29.559 NM_001177781
NM_001033251
Gpr174

G protein-coupled receptor 174

chr5_-_101001191 29.266 Plac8
placenta-specific 8
chr7_+_51827955 28.698 Napsa
napsin A aspartic peptidase
chr7_+_150191542 28.395 NM_001128081
NM_001128082
NM_020286
Tspan32


tetraspanin 32


chr7_-_50788540 28.199 NM_001111058
NM_021293
Cd33

CD33 antigen

chr5_-_101001209 28.108 NM_139198
Plac8
placenta-specific 8
chr7_+_129432810 28.095 Prkcb
protein kinase C, beta
chr7_+_25155279 28.048 NM_001163510
NM_008433
Kcnn4

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

chr5_-_138299171 27.577 NM_133209
Pilrb1
paired immunoglobin-like type 2 receptor beta 1
chr7_+_133728483 27.366 NM_138310
Apobr
apolipoprotein B receptor
chr10_-_61960613 27.274 Srgn
serglycin
chrX_+_104284572 26.382 NM_172435
P2ry10
purinergic receptor P2Y, G-protein coupled 10
chr1_+_60803231 26.245 NM_007642
Cd28
CD28 antigen
chr11_+_100740999 25.854 Stat5a
signal transducer and activator of transcription 5A
chr11_-_79344055 25.817 NM_001033711
NM_010161
NM_146023
Evi2a

Evi2b
ecotropic viral integration site 2a

ecotropic viral integration site 2b
chr3_-_135271220 25.699 Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
chr12_+_87027595 25.528 NM_016767
Batf
basic leucine zipper transcription factor, ATF-like
chr13_-_55122556 25.488 Hk3
hexokinase 3
chr1_+_173319048 25.087 NM_001005508
Arhgap30
Rho GTPase activating protein 30
chr6_-_122552269 24.400 NM_001134391
NM_031159
Apobec1

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1

chr17_+_47736273 24.338 Ccnd3
cyclin D3
chr7_-_134281327 23.985 NM_001037810
NM_009259
Spn

sialophorin

chr3_+_84470230 23.882 Tmem154
transmembrane protein 154
chr13_-_55122670 23.487 NM_001033245
Hk3
hexokinase 3
chr19_+_5878465 23.382 NM_134154
Slc25a45
solute carrier family 25, member 45
chr7_-_147174332 23.280 Adam8
a disintegrin and metallopeptidase domain 8
chr7_+_25155455 23.142 Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr11_-_106175797 22.905 NM_008339
Cd79b
CD79B antigen
chr3_+_84470113 22.747 NM_177260
Tmem154
transmembrane protein 154
chr3_-_106592919 22.684 NM_007651
Cd53
CD53 antigen
chrX_-_98929396 22.618 NM_009910
Cxcr3
chemokine (C-X-C motif) receptor 3
chr6_-_123239765 22.602 Clec4e
C-type lectin domain family 4, member e
chr19_+_4154645 22.295 NM_016933
Ptprcap
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chrX_+_83115611 21.483 NM_001163539
5430427O19Rik
RIKEN cDNA 5430427O19 gene
chr13_-_55122654 20.638 Hk3
hexokinase 3
chr1_+_58859345 20.343 NM_001080126
Casp8
caspase 8
chr5_-_114280434 20.185 NM_009151
Selplg
selectin, platelet (p-selectin) ligand
chr14_+_71174110 20.027 NM_010071
Dok2
docking protein 2
chr11_+_102297953 19.833


chr1_+_40522396 19.821 NM_001161842
NM_001161843
Il18r1

interleukin 18 receptor 1

chr7_+_26471968 19.628 NM_011577
Tgfb1
transforming growth factor, beta 1
chr11_-_95703752 19.502 NM_025659
NM_001163464
Abi3

ABI gene family, member 3

chr7_+_25155415 19.377 Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr10_-_116719183 19.261 NM_017372
Lyz2
lysozyme 2
chr3_-_20142068 19.261 NM_007753
Cpa3
carboxypeptidase A3, mast cell
chr2_+_164773719 18.882 NM_013599
Mmp9
matrix metallopeptidase 9
chr5_-_136606906 18.009 Lrwd1
leucine-rich repeats and WD repeat domain containing 1
chr6_-_98877291 17.676


chr6_+_48986501 17.574 NM_053110
Gpnmb
glycoprotein (transmembrane) nmb
chr10_+_117878101 17.474 NM_008337
Ifng
interferon gamma
chr10_+_51210768 17.449 NM_013532
Lilrb4
leukocyte immunoglobulin-like receptor, subfamily B, member 4
chr14_-_33998251 17.371 NM_001146022
Wdfy4
WD repeat and FYVE domain containing 4
chr9_+_108239210 17.009 Rhoa
ras homolog gene family, member A
chr5_+_34892224 16.806 NM_001145859
NM_001136088
Sh3bp2

SH3-domain binding protein 2

chr11_-_82834223 16.775 NM_001167743
NM_181545
Slfn8

schlafen 8

chr6_-_87483228 16.484 NM_001037727
Arhgap25
Rho GTPase activating protein 25
chr1_+_16678513 16.438 Ly96
lymphocyte antigen 96
chr13_+_55471165 16.302 Rgs14
regulator of G-protein signaling 14
chr17_+_33692639 16.255 NM_053214
Myo1f
myosin IF
chr8_+_28370796 16.199 NM_007918
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
chr19_+_4214263 16.189 Clcf1
cardiotrophin-like cytokine factor 1
chr14_-_56880985 16.126 NM_013542
Gzmb
granzyme B
chr12_+_105474449 15.987 Serpina3g
serine (or cysteine) peptidase inhibitor, clade A, member 3G
chr2_+_32576591 15.685 NM_013781
Sh2d3c
SH2 domain containing 3C
chr2_-_73323746 15.641 Wipf1
WAS/WASL interacting protein family, member 1
chr10_+_79482419 15.614 NM_027521
Hmha1
histocompatibility (minor) HA-1
chr1_-_196957694 15.588 NM_013499
Cr1l
complement component (3b/4b) receptor 1-like
chr19_-_6932673 15.542 NM_001081291
Ccdc88b
coiled-coil domain containing 88B
chr5_+_65522325 15.476 NM_175174
Klhl5
kelch-like 5 (Drosophila)
chr2_-_60590923 15.446 Rbms1
RNA binding motif, single stranded interacting protein 1
chr7_+_129776837 15.395 Prkcb
protein kinase C, beta
chr1_+_173489323 15.242 NM_018729
Cd244
LOC677008
CD244 natural killer cell receptor 2B4
natural killer cell receptor 2B4-like
chr19_+_9026020 15.172 Mta2
metastasis-associated gene family, member 2
chr9_-_57110250 15.132 NM_028820
1700017B05Rik
RIKEN cDNA 1700017B05 gene
chr4_-_46417054 15.123 NM_053149
Hemgn
hemogen
chrX_+_104344265 15.056 NM_001122596
A630033H20Rik
RIKEN cDNA A630033H20 gene
chrX_+_7156801 15.020 NM_054039
Foxp3
forkhead box P3
chr1_+_16678536 14.927 NM_001159711
NM_016923
Ly96

lymphocyte antigen 96

chr18_+_54113094 14.876 Csnk1g3
casein kinase 1, gamma 3
chr13_+_55471092 14.832 NM_016758
Rgs14
regulator of G-protein signaling 14
chr12_+_105452740 14.796 NM_009251
NM_001168294
NM_001168295
NM_001033335
Serpina3g
Serpina3f


Serpina3h
serine (or cysteine) peptidase inhibitor, clade A, member 3G
serine (or cysteine) peptidase inhibitor, clade A, member 3F


serine (or cysteine) peptidase inhibitor, clade A, member 3H
chr15_-_5058532 14.727 NM_001163138
Card6
caspase recruitment domain family, member 6
chr16_+_57353389 14.548 NM_001040397
Filip1l
filamin A interacting protein 1-like
chr10_-_116719364 14.470 Lyz2
lysozyme 2
chr13_-_37142112 14.290 NM_001166391
F13a1
coagulation factor XIII, A1 subunit
chr11_-_115884712 14.239 H3f3b
H3 histone, family 3B
chr10_+_66648458 14.211 Jmjd1c
jumonji domain containing 1C
chr6_+_57531124 14.185 Herc6
hect domain and RLD 6
chr10_+_28388165 13.973 NM_178666
Themis
thymocyte selection associated
chr4_+_63221260 13.845 NM_144905
6330416G13Rik
RIKEN cDNA 6330416G13 gene
chr1_-_175157322 13.818 NM_010184
Fcer1a
Fc receptor, IgE, high affinity I, alpha polypeptide
chr11_-_16908631 13.756 NM_019549
Plek
pleckstrin
chr5_-_39267928 13.720 NM_013748
Clnk
cytokine-dependent hematopoietic cell linker
chr6_-_87740264 13.538 Rab43
RAB43, member RAS oncogene family
chr6_+_17616617 13.525 Capza2
capping protein (actin filament) muscle Z-line, alpha 2
chr6_+_17699145 13.469 NM_001083315
NM_022332
St7

suppression of tumorigenicity 7

chr9_+_5298516 13.393 NM_009807
Casp1
caspase 1
chr1_+_174405490 13.310 NM_029612
Slamf9
SLAM family member 9
chr8_-_112102946 13.232 Hp
haptoglobin
chr5_-_65351226 13.173 NM_011604
Tlr6
toll-like receptor 6
chr12_-_32893074 13.124 NM_001146201
NM_020272
NM_001146200
Pik3cg


phosphoinositide-3-kinase, catalytic, gamma polypeptide


chr5_+_116005777 13.041 Pxn
paxillin
chr13_+_55701256 13.020 NM_146045
B4galt7
xylosylprotein beta1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
chr3_-_58329346 12.976 Serp1
stress-associated endoplasmic reticulum protein 1
chr7_-_113102453 12.973 NM_001039160
NM_029000
Gvin1

GTPase, very large interferon inducible 1

chr7_-_113358823 12.973 NM_001039160
NM_029000
Gvin1

GTPase, very large interferon inducible 1

chr10_+_79321979 12.961 Ptbp1
polypyrimidine tract binding protein 1
chr19_-_4305954 12.955 NM_130863
Adrbk1
adrenergic receptor kinase, beta 1
chr6_-_123239886 12.924 NM_019948
Clec4e
C-type lectin domain family 4, member e
chr7_-_133727793 12.841 NM_001146311
Cln3
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr8_-_112103065 12.632 NM_017370
Hp
haptoglobin
chr4_-_129250806 12.571 NM_001162433
Lck
lymphocyte protein tyrosine kinase
chr7_+_150190950 12.542 NM_001128080
Tspan32
tetraspanin 32
chr13_+_51740600 12.524 NM_025415
Cks2
CDC28 protein kinase regulatory subunit 2
chr6_-_40535762 12.477 NM_001038604
NM_021364
Clec5a

C-type lectin domain family 5, member a

chr2_+_172219293 12.433 NM_001033538
NM_001080820
Cass4

Cas scaffolding protein family member 4

chr4_-_118954780 12.417 Ybx1
Y box protein 1
chr9_-_113563906 12.388 Pdcd6ip
programmed cell death 6 interacting protein
chr9_+_108953672 12.366 Shisa5
shisa homolog 5 (Xenopus laevis)
chrX_-_71156567 12.271 NM_001162423
NM_001162424
NM_138630
Arhgap4


Rho GTPase activating protein 4


chr5_-_148211881 12.207 NM_010229
Flt3
FMS-like tyrosine kinase 3
chr10_+_32803288 12.202 NM_029726
Trdn
triadin
chr10_-_124765435 12.122 NM_011391
Slc16a7
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr1_-_195027508 12.092 NM_153137
Traf3ip3
TRAF3 interacting protein 3
chr4_-_46416895 12.090 Hemgn
hemogen
chr16_+_44765848 12.090 NM_021325
Cd200r1
CD200 receptor 1
chrX_+_104344792 12.080 NM_001122595
A630033H20Rik
RIKEN cDNA A630033H20 gene
chr2_-_156712810 12.060 NM_029983
Sla2
Src-like-adaptor 2
chr14_+_56590264 12.035 NM_001024714
Cma2
chymase 2, mast cell
chr8_-_112102961 12.011 Hp
haptoglobin
chrX_-_71526939 11.947 Dnase1l1
deoxyribonuclease 1-like 1
chr17_+_4995073 11.944 NM_001085355
Arid1b
AT rich interactive domain 1B (SWI-like)
chr6_+_48986625 11.935 Gpnmb
glycoprotein (transmembrane) nmb
chr11_-_117630476 11.876 Tmc6
transmembrane channel-like gene family 6
chr9_+_108953692 11.871 Shisa5
shisa homolog 5 (Xenopus laevis)
chr13_+_63116293 11.604 NM_028079
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr11_+_75345164 11.539 NM_173388
Slc43a2
solute carrier family 43, member 2
chr2_+_156393681 11.527


chr5_-_148211857 11.477 Flt3
FMS-like tyrosine kinase 3
chr17_+_35958628 11.372 NM_133662
Ier3
immediate early response 3
chr19_+_4214369 11.226 NM_019952
Clcf1
cardiotrophin-like cytokine factor 1
chr7_+_148578056 11.152 NM_011528
Taldo1
transaldolase 1
chr8_-_73223897 11.106 Gm11175
predicted gene 11175
chr9_+_114640266 11.064 NM_026036
Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr7_-_148202779 11.057 NM_001033632
Ifitm6
interferon induced transmembrane protein 6
chr1_-_158604396 10.979 NM_023141
Tor3a
torsin family 3, member A
chr19_-_5468482 10.927 NM_009985
Ctsw
cathepsin W
chr6_-_129573858 10.918 NM_001083322
Klrk1
killer cell lectin-like receptor subfamily K, member 1
chr5_+_77694506 10.916 NM_011263
Rest
RE1-silencing transcription factor
chr19_+_8840883 10.847 Nxf1
nuclear RNA export factor 1 homolog (S. cerevisiae)
chr1_+_172949049 10.826 NM_144559
Fcgr4
Fc receptor, IgG, low affinity IV
chr3_+_95466898 10.743


chr13_+_51740804 10.737 Cks2
CDC28 protein kinase regulatory subunit 2
chr1_-_87633103 10.689 NM_177055
A630001G21Rik
RIKEN cDNA A630001G21 gene

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.97 3.85e-11 GO:0002376 immune system process
1.45 1.16e-08 GO:0048518 positive regulation of biological process
1.82 2.52e-08 GO:0042981 regulation of apoptosis
1.81 2.83e-08 GO:0043067 regulation of programmed cell death
1.79 4.42e-08 GO:0010941 regulation of cell death
1.45 1.93e-07 GO:0048522 positive regulation of cellular process
1.27 1.96e-06 GO:0043170 macromolecule metabolic process
2.37 3.01e-06 GO:0001775 cell activation
2.29 4.15e-06 GO:0050776 regulation of immune response
2.19 4.15e-06 GO:0009611 response to wounding
1.53 7.40e-06 GO:0006950 response to stress
1.90 1.38e-05 GO:0002682 regulation of immune system process
2.35 1.63e-05 GO:0006917 induction of apoptosis
2.34 1.85e-05 GO:0012502 induction of programmed cell death
1.41 1.93e-05 GO:0048519 negative regulation of biological process
2.04 2.15e-05 GO:0080134 regulation of response to stress
2.39 2.77e-05 GO:0045321 leukocyte activation
1.26 4.34e-05 GO:0044260 cellular macromolecule metabolic process
1.21 4.72e-05 GO:0044238 primary metabolic process
1.28 6.60e-05 GO:0019222 regulation of metabolic process
1.96 6.67e-05 GO:0043068 positive regulation of programmed cell death
1.94 7.92e-05 GO:0010942 positive regulation of cell death
1.31 8.09e-05 GO:0031323 regulation of cellular metabolic process
1.95 1.04e-04 GO:0043065 positive regulation of apoptosis
2.05 1.39e-04 GO:0002684 positive regulation of immune system process
1.61 1.54e-04 GO:0035556 intracellular signal transduction
1.31 1.71e-04 GO:0060255 regulation of macromolecule metabolic process
2.06 1.97e-04 GO:0006955 immune response
1.47 2.64e-04 GO:0048583 regulation of response to stimulus
3.25 2.80e-04 GO:0002703 regulation of leukocyte mediated immunity
3.45 2.82e-04 GO:0002706 regulation of lymphocyte mediated immunity
1.35 3.17e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.29 3.34e-04 GO:0080090 regulation of primary metabolic process
1.33 5.85e-04 GO:0031326 regulation of cellular biosynthetic process
1.35 6.05e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.38 6.53e-04 GO:0048523 negative regulation of cellular process
2.27 6.65e-04 GO:0050778 positive regulation of immune response
1.34 6.77e-04 GO:0019538 protein metabolic process
2.37 7.18e-04 GO:0046649 lymphocyte activation
2.58 7.31e-04 GO:0002697 regulation of immune effector process
1.33 8.32e-04 GO:0009889 regulation of biosynthetic process
2.20 9.74e-04 GO:0031347 regulation of defense response
2.35 1.37e-03 GO:0006954 inflammatory response
1.33 1.51e-03 GO:0010468 regulation of gene expression
2.04 1.88e-03 GO:0048534 hemopoietic or lymphoid organ development
2.25 2.11e-03 GO:0002694 regulation of leukocyte activation
6.38 2.25e-03 GO:0002704 negative regulation of leukocyte mediated immunity
6.38 2.25e-03 GO:0002707 negative regulation of lymphocyte mediated immunity
2.21 2.55e-03 GO:0050865 regulation of cell activation
1.80 2.99e-03 GO:0006952 defense response
1.18 3.40e-03 GO:0044237 cellular metabolic process
7.85 3.74e-03 GO:0002820 negative regulation of adaptive immune response
7.85 3.74e-03 GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
1.98 4.01e-03 GO:0002520 immune system development
3.85 5.10e-03 GO:0002698 negative regulation of immune effector process
2.44 8.51e-03 GO:0002521 leukocyte differentiation
3.90 8.83e-03 GO:0031341 regulation of cell killing
1.15 9.51e-03 GO:0008152 metabolic process
1.32 1.06e-02 GO:0051252 regulation of RNA metabolic process
2.22 1.44e-02 GO:0051249 regulation of lymphocyte activation
1.32 1.57e-02 GO:0006355 regulation of transcription, DNA-dependent
9.56 1.66e-02 GO:0002710 negative regulation of T cell mediated immunity
3.04 1.66e-02 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
2.48 1.84e-02 GO:0002764 immune response-regulating signaling pathway
2.51 2.06e-02 GO:0042110 T cell activation
2.38 2.13e-02 GO:0031349 positive regulation of defense response
1.59 2.15e-02 GO:0048584 positive regulation of response to stimulus
1.72 2.19e-02 GO:0008284 positive regulation of cell proliferation
1.65 2.48e-02 GO:0012501 programmed cell death
3.61 2.60e-02 GO:0050777 negative regulation of immune response
2.31 2.71e-02 GO:0002253 activation of immune response
2.93 2.93e-02 GO:0002819 regulation of adaptive immune response
7.44 2.97e-02 GO:0032689 negative regulation of interferon-gamma production
6.38 3.02e-02 GO:0071634 regulation of transforming growth factor-beta production
2.82 3.40e-02 GO:0002699 positive regulation of immune effector process
1.31 3.60e-02 GO:0044267 cellular protein metabolic process
1.95 4.43e-02 GO:0030097 hemopoiesis
1.59 4.66e-02 GO:0016265 death
1.27 4.83e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.13 9.13e-06 GO:0005622 intracellular
1.13 2.46e-05 GO:0044424 intracellular part
1.49 2.96e-05 GO:0005829 cytosol
1.23 8.41e-05 GO:0005634 nucleus
1.14 2.23e-04 GO:0043229 intracellular organelle
1.13 3.74e-04 GO:0043226 organelle
2.26 5.72e-04 GO:0009897 external side of plasma membrane
1.14 1.18e-03 GO:0043231 intracellular membrane-bounded organelle
1.14 1.27e-03 GO:0043227 membrane-bounded organelle
1.13 2.80e-03 GO:0005737 cytoplasm
1.74 4.08e-03 GO:0009986 cell surface
1.32 1.83e-02 GO:0005576 extracellular region
1.16 2.13e-02 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.15 1.08e-07 GO:0005488 binding
1.22 4.85e-05 GO:0005515 protein binding
1.32 8.29e-04 GO:0003676 nucleic acid binding
1.61 8.98e-03 GO:0043565 sequence-specific DNA binding
1.35 1.11e-02 GO:0003677 DNA binding
1.50 1.42e-02 GO:0030528 transcription regulator activity
1.98 1.92e-02 GO:0019901 protein kinase binding