Motif ID: RXRG_dimer.p3

Z-value: 0.806


Transcription factors associated with RXRG_dimer.p3:

Gene SymbolEntrez IDGene Name
Nr1h2 22260 nuclear receptor subfamily 1, group H, member 2
Ppara 19013 peroxisome proliferator activated receptor alpha
Pparg 19016 peroxisome proliferator activated receptor gamma
Rxra 20181 retinoid X receptor alpha
Rxrb 20182 retinoid X receptor beta
Rxrg 20183 retinoid X receptor gamma

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pparachr15_+_855660550.403.3e-08Click!
Ppargchr6_+_1153110780.312.6e-05Click!
Nr1h2chr7_-_518092550.281.7e-04Click!
Rxrbchr17_+_341692890.249.9e-04Click!
Rxrgchr1_+_169528706,
chr1_+_169528838		0.214.3e-03Click!
Rxrachr2_+_275326920.163.0e-02Click!


Activity profile for motif RXRG_dimer.p3.

activity profile for motif RXRG_dimer.p3


Sorted Z-values histogram for motif RXRG_dimer.p3

Sorted Z-values for motif RXRG_dimer.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of RXRG_dimer.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_172978566 19.947 NM_011044
 Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
chr7_+_50699457 7.881 NM_026695
 Etfb
electron transferring flavoprotein, beta polypeptide
chr11_+_70471297 7.504 NM_007933
 Eno3
enolase 3, beta muscle
chr9_+_108564418 7.477 NM_020520
 Slc25a20
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr15_-_27560282 7.367 NM_001013792
 Fam105b
family with sequence similarity 105, member B
chr11_+_74462965 6.683 NM_001081158
 1300001I01Rik
RIKEN cDNA 1300001I01 gene
chr18_+_70728508 6.648 Mbd2
methyl-CpG binding domain protein 2
chr11_+_70471347 5.870 Eno3
enolase 3, beta muscle
chr16_+_48872720 5.730 NM_181596
 Retnlg
resistin like gamma
chr2_+_92215590 4.892 Pex16
peroxisomal biogenesis factor 16
chr2_-_6466116 4.861 Celf2
CUGBP, Elav-like family member 2
chr14_+_122933538 4.715 NM_144844
 Pcca
propionyl-Coenzyme A carboxylase, alpha polypeptide
chr14_+_122933560 4.707 Pcca
propionyl-Coenzyme A carboxylase, alpha polypeptide
chr4_+_59594569 4.620 Hsdl2
hydroxysteroid dehydrogenase like 2
chr16_+_44139908 4.563 NM_028108
 Naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr7_+_31017305 4.420 Polr2i
polymerase (RNA) II (DNA directed) polypeptide I
chr2_+_92215395 4.346 NM_145122
 Pex16
peroxisomal biogenesis factor 16
chr17_-_34164996 4.251 NM_013543
 H2-Ke6
H2-K region expressed gene 6
chr18_+_74938827 4.124 NM_177470
 Acaa2
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)
chr6_+_70557402 4.053



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 20 entries
Enrichment   P-value GO Accession GO Term
8.60 3.45e-03 GO:0044242 cellular lipid catabolic process
8.44 2.54e-04 GO:0022900 electron transport chain
5.20 1.22e-03 GO:0006091 generation of precursor metabolites and energy
4.82 6.75e-03 GO:0006631 fatty acid metabolic process
4.35 8.54e-03 GO:0034622 cellular macromolecular complex assembly
4.16 6.45e-03 GO:0032787 monocarboxylic acid metabolic process
4.15 6.70e-03 GO:0034621 cellular macromolecular complex subunit organization
3.18 4.50e-03 GO:0044255 cellular lipid metabolic process
2.97 1.25e-02 GO:0042180 cellular ketone metabolic process
2.96 1.76e-03 GO:0055114 oxidation-reduction process
2.90 2.87e-02 GO:0019752 carboxylic acid metabolic process
2.90 2.87e-02 GO:0043436 oxoacid metabolic process
2.84 3.67e-02 GO:0043933 macromolecular complex subunit organization
2.83 3.93e-02 GO:0006082 organic acid metabolic process
2.58 3.95e-02 GO:0006629 lipid metabolic process
2.07 2.61e-02 GO:0044281 small molecule metabolic process
1.70 2.91e-02 GO:0009058 biosynthetic process
1.67 1.95e-07 GO:0044237 cellular metabolic process
1.61 4.24e-08 GO:0008152 metabolic process
1.54 1.77e-04 GO:0044238 primary metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 18 of 18 entries
Enrichment   P-value GO Accession GO Term
6.14 2.68e-02 GO:0044455 mitochondrial membrane part
5.90 1.45e-03 GO:0005759 mitochondrial matrix
4.03 2.02e-03 GO:0005743 mitochondrial inner membrane
3.84 2.22e-04 GO:0005740 mitochondrial envelope
3.82 3.65e-03 GO:0019866 organelle inner membrane
3.72 2.32e-05 GO:0044429 mitochondrial part
3.56 2.24e-03 GO:0031966 mitochondrial membrane
2.85 2.24e-08 GO:0005739 mitochondrion
2.84 8.18e-03 GO:0031967 organelle envelope
2.80 9.96e-03 GO:0031975 envelope
1.64 8.03e-06 GO:0044444 cytoplasmic part
1.38 9.20e-04 GO:0043227 membrane-bounded organelle
1.37 1.52e-03 GO:0043231 intracellular membrane-bounded organelle
1.37 1.88e-03 GO:0005737 cytoplasm
1.35 6.33e-04 GO:0043226 organelle
1.34 9.94e-04 GO:0043229 intracellular organelle
1.32 1.00e-04 GO:0044424 intracellular part
1.31 1.20e-04 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
27.09 3.20e-02 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
3.90 2.79e-02 GO:0048037 cofactor binding
1.50 5.19e-03 GO:0003824 catalytic activity
1.24 2.24e-02 GO:0005488 binding