Motif ID: SNAI1..3.p2

Z-value: 3.087


Transcription factors associated with SNAI1..3.p2:

Gene SymbolEntrez IDGene Name
Snai1 20613 snail homolog 1 (Drosophila)
Snai2 20583 snail homolog 2 (Drosophila)
Snai3 30927 snail homolog 3 (Drosophila)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Snai1chr2_+_167363696,
chr2_+_167363769
-0.402.6e-08Click!
Snai3chr8_-_124984513-0.153.8e-02Click!
Snai2chr16_+_14705932-0.129.9e-02Click!


Activity profile for motif SNAI1..3.p2.

activity profile for motif SNAI1..3.p2


Sorted Z-values histogram for motif SNAI1..3.p2

Sorted Z-values for motif SNAI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SNAI1..3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_69778907 105.323 NM_016887
Cldn7
claudin 7
chr11_+_69778998 94.841 Cldn7
claudin 7
chr7_-_30066867 81.075 Spint2
serine protease inhibitor, Kunitz type 2
chr7_-_30066910 80.944 NM_001082548
NM_011464
Spint2

serine protease inhibitor, Kunitz type 2

chr7_-_30066642 79.335 Spint2
serine protease inhibitor, Kunitz type 2
chr15_+_54402914 71.308 NM_178920
Mal2
mal, T-cell differentiation protein 2
chr15_+_54402988 57.946 Mal2
mal, T-cell differentiation protein 2
chr12_-_74647339 48.321 NM_178715
Tmem30b
transmembrane protein 30B
chr13_-_101322672 47.759 Ocln
occludin
chr13_-_101322557 47.544 Ocln
occludin
chr13_-_101322416 45.767 NM_008756
Ocln
occludin
chr8_+_109127326 44.275 Cdh1
cadherin 1
chr11_+_115685417 41.742 Llgl2
lethal giant larvae homolog 2 (Drosophila)
chr4_-_11313886 41.551 NM_194055
Esrp1
epithelial splicing regulatory protein 1
chr2_+_119063194 41.061


chr11_+_115685365 39.790 NM_145438
Llgl2
lethal giant larvae homolog 2 (Drosophila)
chr1_+_137715174 38.435 NM_133664
Lad1
ladinin
chr1_+_137715339 37.412 Lad1
ladinin
chr9_-_30939272 36.853 St14
suppression of tumorigenicity 14 (colon carcinoma)
chr2_+_167906462 36.526 NM_021409
Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr7_-_31758390 36.492 NM_001164184
NM_001164185
NM_017405
Lsr


lipolysis stimulated lipoprotein receptor


chr3_-_108339375 35.905 NM_001033304
5330417C22Rik
RIKEN cDNA 5330417C22 gene
chr8_+_87514471 35.517 NM_001167991
NM_133255
Hook2

hook homolog 2 (Drosophila)

chr1_+_137715515 35.413 Lad1
ladinin
chr15_+_101242832 35.263 NM_033073
Krt7
keratin 7
chr9_-_50554613 35.216 NM_025865
2310030G06Rik
RIKEN cDNA 2310030G06 gene
chr17_+_57201623 34.812 NM_177638
Crb3
crumbs homolog 3 (Drosophila)
chr18_-_64820573 33.850 NM_001001488
Atp8b1
ATPase, class I, type 8B, member 1
chr15_-_76444249 33.833 Slc39a4
solute carrier family 39 (zinc transporter), member 4
chr2_+_126378563 33.059 NM_011978
Slc27a2
solute carrier family 27 (fatty acid transporter), member 2
chr1_+_173367685 32.932 NM_172647
F11r
F11 receptor
chr8_+_3587791 32.827 2310057J16Rik
RIKEN cDNA 2310057J16 gene
chr9_-_21116703 32.284 Ap1m2
adaptor protein complex AP-1, mu 2 subunit
chr8_+_109127245 31.904 NM_009864
Cdh1
cadherin 1
chr9_-_21116749 31.830 NM_001110300
NM_009678
Ap1m2

adaptor protein complex AP-1, mu 2 subunit

chr4_+_133074877 31.736 NM_001083916
NM_133707
1810019J16Rik

RIKEN cDNA 1810019J16 gene

chr5_-_53604673 31.185 NM_172710
Sel1l3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr5_-_44492908 31.062 NM_001163577
NM_008935
Prom1

prominin 1

chr5_-_53604536 30.604 Sel1l3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr4_+_118199847 30.201 NM_025572
2610528J11Rik
RIKEN cDNA 2610528J11 gene
chr5_+_135462204 30.162 Cldn3
claudin 3
chr5_+_135462067 29.920 NM_009902
Cldn3
claudin 3
chr11_-_80593259 29.747 NM_177390
Myo1d
myosin ID
chr6_+_68375560 29.083 Igkv16-104
immunoglobulin kappa variable 16-104
chr5_-_93473976 28.289 NM_175270
Ankrd56
ankyrin repeat domain 56
chr11_-_100007218 28.162 NM_008471
Krt19
keratin 19
chr4_+_133074949 28.147 1810019J16Rik
RIKEN cDNA 1810019J16 gene
chr16_+_36694118 27.674 NM_134109
Ildr1
immunoglobulin-like domain containing receptor 1
chr2_+_119063134 27.458 Spint1
serine protease inhibitor, Kunitz type 1
chr3_-_151828863 27.265 NM_016867
Gipc2
GIPC PDZ domain containing family, member 2
chr2_+_164388211 27.237 NM_026323
Wfdc2
WAP four-disulfide core domain 2
chr16_+_36694063 27.140 Ildr1
immunoglobulin-like domain containing receptor 1
chr2_+_119063090 26.904 NM_016907
Spint1
serine protease inhibitor, Kunitz type 1
chr5_-_140290195 26.744 NM_001161548
Tmem184a
transmembrane protein 184a
chr18_+_74602260 26.729 NM_201600
Myo5b
myosin VB
chr8_+_3587675 26.212 2310057J16Rik
RIKEN cDNA 2310057J16 gene
chr4_+_133074976 26.195 1810019J16Rik
RIKEN cDNA 1810019J16 gene
chr17_+_28906259 26.141 NM_011950
Mapk13
mitogen-activated protein kinase 13
chr7_-_4741145 25.440 NM_029384
2210411K11Rik
RIKEN cDNA 2210411K11 gene
chr10_+_19868725 24.562 NM_001198635
NM_008635
Mtap7

microtubule-associated protein 7

chr9_-_41932195 24.037 Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr2_+_119063436 23.960 Spint1
serine protease inhibitor, Kunitz type 1
chr1_+_74455956 23.855 NM_009509
Vil1
villin 1
chr18_+_20716598 23.739 NM_007883
Dsg2
desmoglein 2
chr7_-_31758185 23.523 Lsr
lipolysis stimulated lipoprotein receptor
chr6_+_125271356 23.503 NM_011324
Scnn1a
sodium channel, nonvoltage-gated 1 alpha
chr10_+_75356142 23.442 NM_024440
Derl3
Der1-like domain family, member 3
chr8_+_58773380 23.284 Hpgd
hydroxyprostaglandin dehydrogenase 15 (NAD)
chr8_+_58773321 23.276 NM_008278
Hpgd
hydroxyprostaglandin dehydrogenase 15 (NAD)
chr15_-_75839859 23.083 NM_001168253
Fam83h
family with sequence similarity 83, member H
chr1_-_155033576 22.921 NM_008485
Lamc2
laminin, gamma 2
chr16_-_88563421 22.353 NM_018778
Cldn8
claudin 8
chr9_-_41932371 21.956 NM_011436
Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr9_-_114753191 21.846 NM_027294
Cmtm8
CKLF-like MARVEL transmembrane domain containing 8
chr4_-_115840142 21.797 NM_133681
Tspan1
tetraspanin 1
chr11_-_100259061 21.503 Jup
junction plakoglobin
chr2_-_65962685 21.346 NM_015736
Galnt3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3
chr8_-_108660711 21.288 Esrp2
epithelial splicing regulatory protein 2
chr8_-_108660736 21.274 NM_176838
Esrp2
epithelial splicing regulatory protein 2
chr11_+_115024626 20.934 NM_012030
Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr7_+_28856254 20.825 NM_001122603
Fcgbp
Fc fragment of IgG binding protein
chr4_+_114761644 20.631 Pdzk1ip1
PDZK1 interacting protein 1
chr5_-_66542161 20.509 NM_178446
Rbm47
RNA binding motif protein 47
chr15_-_37162895 20.501 Gm16136
predicted gene 16136
chr15_-_34608840 20.497 Nipal2
NIPA-like domain containing 2
chr1_+_78306890 20.313 NM_001004173
Sgpp2
sphingosine-1-phosphate phosphotase 2
chr16_-_88563379 20.299 Cldn8
claudin 8
chr19_+_25484006 20.222 Kank1
KN motif and ankyrin repeat domains 1
chr15_-_37162666 20.123 Grhl2
grainyhead-like 2 (Drosophila)
chr19_+_6306456 20.112 NM_001033342
Cdc42bpg
CDC42 binding protein kinase gamma (DMPK-like)
chr3_-_88351996 19.971 NM_016899
Rab25
RAB25, member RAS oncogene family
chr16_-_97832640 19.862 Tmprss2
transmembrane protease, serine 2
chr5_-_66542128 19.784 Rbm47
RNA binding motif protein 47
chr5_+_102194207 19.758 Cds1
CDP-diacylglycerol synthase 1
chr9_+_53109774 19.535 NM_176846
Exph5
exophilin 5
chr4_-_118216327 19.460 NM_172383
Tmem125
transmembrane protein 125
chr5_-_145118920 19.445 NM_025833
Baiap2l1
BAI1-associated protein 2-like 1
chr16_+_16213397 19.274 Pkp2
plakophilin 2
chr12_-_112907828 19.236 Ckb
creatine kinase, brain
chr16_-_97832672 18.849 Tmprss2
transmembrane protease, serine 2
chr2_+_122463622 18.810 NM_001004174
AA467197
expressed sequence AA467197
chr11_+_96790581 18.623 NM_146026
Prr15l
proline rich 15-like
chr5_+_102194126 18.556 NM_173370
Cds1
CDP-diacylglycerol synthase 1
chr4_+_114761312 18.539 NM_001164557
NM_001164558
NM_026018
Pdzk1ip1


PDZK1 interacting protein 1


chr15_-_88991213 18.516 Plxnb2
plexin B2
chr16_-_14201162 18.162 Myh11
myosin, heavy polypeptide 11, smooth muscle
chr16_-_97985323 18.080 NM_023663
Ripk4
receptor-interacting serine-threonine kinase 4
chr9_+_83441886 17.821 NM_172507
Sh3bgrl2
SH3 domain binding glutamic acid-rich protein like 2
chr10_+_43298969 17.812 NM_009846
Cd24a
CD24a antigen
chr12_-_36769054 17.594 NM_025359
Tspan13
tetraspanin 13
chr6_-_8728094 17.587 Ica1
islet cell autoantigen 1
chr8_+_3587449 17.426 NM_001163749
NM_027171
2310057J16Rik

RIKEN cDNA 2310057J16 gene

chr7_-_3629111 17.334 NM_181820
Tmc4
transmembrane channel-like gene family 4
chrX_+_136145321 17.189 Rnf128
ring finger protein 128
chr15_-_34608600 17.064 Nipal2
NIPA-like domain containing 2
chr5_+_75971011 16.830 NM_001122733
NM_021099
Kit

kit oncogene

chr6_+_43215604 16.819 NM_133674
Arhgef5
Rho guanine nucleotide exchange factor (GEF) 5
chr4_-_133785006 16.592 Cnksr1
connector enhancer of kinase suppressor of Ras 1
chr7_+_108470264 16.434 Stard10
START domain containing 10
chr17_+_88036128 16.271 Epcam
epithelial cell adhesion molecule
chr15_-_101834713 16.266 Krt8
keratin 8
chr4_-_154735351 16.244 NM_008860
Prkcz
protein kinase C, zeta
chr7_+_148401781 16.165 Rassf7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr17_+_47573557 16.153 NM_145489
AI661453
expressed sequence AI661453
chr15_-_101834741 16.147 Krt8
keratin 8
chr15_-_101834744 16.094 Krt8
keratin 8
chr15_-_101834746 16.076 NM_031170
Krt8
keratin 8
chrX_+_98572571 15.979 NM_008124
Gjb1
gap junction protein, beta 1
chr10_-_61573705 15.947 NM_027251
2010107G23Rik
RIKEN cDNA 2010107G23 gene
chr15_-_78236262 15.852 NM_009437
Tst
thiosulfate sulfurtransferase, mitochondrial
chr14_+_102129129 15.781 NM_201529
Lmo7
LIM domain only 7
chr10_+_88348725 15.554 NM_145423
Slc5a8
solute carrier family 5 (iodide transporter), member 8
chr16_-_5132502 15.533 NM_008909
Ppl
periplakin
chr4_+_84851330 15.511 NM_019535
Sh3gl2
SH3-domain GRB2-like 2
chr7_-_3629066 15.488 Tmc4
transmembrane channel-like gene family 4
chr7_+_148401731 15.457 NM_025886
Rassf7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr3_-_94590356 15.455 NM_001037711
Cgn
cingulin
chr18_+_36508277 15.449 NM_001081365
0610010O12Rik
RIKEN cDNA 0610010O12 gene
chr4_-_129952771 15.372 NM_172702
Serinc2
serine incorporator 2
chr1_-_52784161 15.204 NM_133829
NM_178081
Mfsd6

major facilitator superfamily domain containing 6

chr15_-_97738692 15.143 NM_009504
Vdr
vitamin D receptor
chr17_+_24544500 14.828 Abca3
ATP-binding cassette, sub-family A (ABC1), member 3
chr15_-_34608458 14.546 NM_145469
Nipal2
NIPA-like domain containing 2
chr15_+_101858606 14.492 NM_010664
Krt18
keratin 18
chr5_-_145118758 14.364 Baiap2l1
BAI1-associated protein 2-like 1
chr16_+_16213434 14.327 NM_026163
Pkp2
plakophilin 2
chr11_-_100259048 14.316 NM_010593
Jup
junction plakoglobin
chr14_+_102239673 14.297 Lmo7
LIM domain only 7
chr10_-_18463500 14.216 NM_001033258
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr16_-_52452766 14.165 Alcam
activated leukocyte cell adhesion molecule
chr4_+_106295053 14.141 NM_177667
Ttc22
tetratricopeptide repeat domain 22
chr2_-_93302538 13.748 Cd82
CD82 antigen
chr8_-_113917651 13.666 NM_178086
Fa2h
fatty acid 2-hydroxylase
chr4_-_75779379 13.623 NM_001014288
Ptprd
protein tyrosine phosphatase, receptor type, D
chr7_+_114738722 13.555 Ppfibp2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr2_-_93302621 13.513 NM_007656
Cd82
CD82 antigen
chr17_-_35109068 13.499 NM_010479
Hspa1a
heat shock protein 1A
chr4_+_95634005 13.468 NM_030014
Hook1
hook homolog 1 (Drosophila)
chr17_+_23797470 13.446 NM_153784
Ccdc64b
coiled-coil domain containing 64B
chr5_-_75098910 13.432 NM_001159577
Lnx1
ligand of numb-protein X 1
chr17_-_35096167 13.415 NM_010478
Hspa1b
Hspa1a
heat shock protein 1B
heat shock protein 1A
chr13_-_96661704 13.367 NM_027711
Iqgap2
IQ motif containing GTPase activating protein 2
chr4_-_136448748 13.358 NM_007574
C1qc
complement component 1, q subcomponent, C chain
chr4_-_128925666 13.324 NM_001033189
C77080
expressed sequence C77080
chr13_-_62989595 13.253 NM_019395
Fbp1
fructose bisphosphatase 1
chr1_+_132723258 13.198 NM_011082
Pigr
polymeric immunoglobulin receptor
chr7_-_148286422 13.183 NM_023059
Sigirr
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr10_+_19868276 13.132 Mtap7
microtubule-associated protein 7
chr10_-_61693914 13.010 Tspan15
tetraspanin 15
chr2_-_157972041 12.973 NM_009373
Tgm2
transglutaminase 2, C polypeptide
chr6_-_8728481 12.931 NM_010492
Ica1
islet cell autoantigen 1
chr7_+_28914482 12.930 NM_001164655
9530053A07Rik
RIKEN cDNA 9530053A07 gene
chr1_+_132723277 12.862 Pigr
polymeric immunoglobulin receptor
chr13_-_101386865 12.747 NM_178410
NM_001038602
Marveld2

MARVEL (membrane-associating) domain containing 2

chr3_+_95392919 12.735 Golph3l
golgi phosphoprotein 3-like
chr13_+_109004589 12.678 NM_029001
Elovl7
ELOVL family member 7, elongation of long chain fatty acids (yeast)
chr11_-_35793590 12.575 NM_170779
Wwc1
WW, C2 and coiled-coil domain containing 1
chr10_+_79285371 12.569 9130017N09Rik
RIKEN cDNA 9130017N09 gene
chr3_+_89032973 12.525 NM_013605
Muc1
mucin 1, transmembrane
chr17_-_28697643 12.511 NM_025469
Clps
colipase, pancreatic
chr4_-_57156490 12.508 Epb4.1l4b
erythrocyte protein band 4.1-like 4b
chr16_-_97832775 12.503 NM_015775
Tmprss2
transmembrane protease, serine 2
chr15_+_80502276 12.399 NM_145986
Fam83f
family with sequence similarity 83, member F
chr8_+_12915892 12.352 NM_178076
Mcf2l
mcf.2 transforming sequence-like
chr2_-_92210955 12.247 NM_001166633
NM_172670
Gyltl1b

glycosyltransferase-like 1B

chr16_-_20716002 12.188 Clcn2
chloride channel 2
chr11_-_74403603 12.148 NM_001015046
Rap1gap2
RAP1 GTPase activating protein 2
chr11_-_115229039 11.991 C630004H02Rik
RIKEN cDNA C630004H02 gene
chr5_-_91069499 11.859 NM_028478
Rassf6
Ras association (RalGDS/AF-6) domain family member 6
chr1_+_40738460 11.813 Slc9a2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr7_+_35904347 11.722 Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr4_+_109088251 11.623 NM_001145948
Ttc39a
tetratricopeptide repeat domain 39A
chr10_-_61693963 11.564 NM_197996
Tspan15
tetraspanin 15
chr18_+_12492494 11.447 NM_010680
Lama3
laminin, alpha 3
chr6_+_116287992 11.417 March8
membrane-associated ring finger (C3HC4) 8
chr1_+_194979305 11.407 NM_016851
Irf6
interferon regulatory factor 6
chr3_+_90341208 11.388 S100a16
S100 calcium binding protein A16
chr7_-_31861665 11.277 NM_008557
Fxyd3
FXYD domain-containing ion transport regulator 3
chr9_+_46037941 11.225


chr6_+_116288075 11.178 NM_027920
March8
membrane-associated ring finger (C3HC4) 8

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.53 1.94e-31 GO:0051179 localization
1.58 8.65e-31 GO:0051234 establishment of localization
1.58 4.45e-30 GO:0006810 transport
1.53 2.25e-15 GO:0065008 regulation of biological quality
1.21 5.00e-15 GO:0008152 metabolic process
1.53 7.87e-14 GO:0044281 small molecule metabolic process
1.60 1.58e-12 GO:0033036 macromolecule localization
1.70 5.95e-11 GO:0006629 lipid metabolic process
1.62 6.75e-11 GO:0008104 protein localization
1.45 1.81e-09 GO:0048583 regulation of response to stimulus
1.66 2.02e-09 GO:0045184 establishment of protein localization
1.69 5.19e-09 GO:0055085 transmembrane transport
1.66 6.61e-09 GO:0015031 protein transport
1.32 8.26e-09 GO:0048856 anatomical structure development
1.34 9.28e-09 GO:0048731 system development
1.18 1.19e-08 GO:0044238 primary metabolic process
1.51 1.30e-08 GO:0009966 regulation of signal transduction
1.41 1.56e-08 GO:0042221 response to chemical stimulus
1.46 2.11e-08 GO:0023051 regulation of signaling
1.31 3.26e-08 GO:0048518 positive regulation of biological process
1.69 6.01e-08 GO:0042180 cellular ketone metabolic process
1.28 7.82e-08 GO:0032502 developmental process
1.69 9.19e-08 GO:0006082 organic acid metabolic process
1.43 1.09e-07 GO:0065009 regulation of molecular function
1.53 1.09e-07 GO:0032879 regulation of localization
1.69 1.14e-07 GO:0019752 carboxylic acid metabolic process
1.69 1.14e-07 GO:0043436 oxoacid metabolic process
1.29 1.29e-07 GO:0016043 cellular component organization
1.61 1.53e-07 GO:0055114 oxidation-reduction process
1.90 3.83e-07 GO:0071702 organic substance transport
1.28 4.49e-07 GO:0007275 multicellular organismal development
1.55 8.06e-07 GO:0009888 tissue development
1.49 1.10e-06 GO:0035556 intracellular signal transduction
1.50 1.20e-06 GO:0051641 cellular localization
1.65 2.11e-06 GO:0016192 vesicle-mediated transport
1.56 2.63e-06 GO:0006811 ion transport
1.29 2.68e-06 GO:0048522 positive regulation of cellular process
1.36 3.92e-06 GO:0048513 organ development
1.89 4.09e-06 GO:0009894 regulation of catabolic process
1.91 4.55e-06 GO:0034220 ion transmembrane transport
1.44 5.35e-06 GO:0050790 regulation of catalytic activity
1.64 7.37e-06 GO:0044255 cellular lipid metabolic process
1.64 7.65e-06 GO:0006812 cation transport
1.51 8.31e-06 GO:0042592 homeostatic process
1.77 9.41e-06 GO:0060429 epithelium development
1.95 1.44e-05 GO:0031329 regulation of cellular catabolic process
1.38 1.52e-05 GO:0051239 regulation of multicellular organismal process
1.15 1.74e-05 GO:0044237 cellular metabolic process
1.29 2.60e-05 GO:0048519 negative regulation of biological process
2.97 2.86e-05 GO:0034330 cell junction organization
2.63 2.97e-05 GO:0000041 transition metal ion transport
1.58 3.46e-05 GO:0070887 cellular response to chemical stimulus
1.30 3.48e-05 GO:0048523 negative regulation of cellular process
1.69 6.00e-05 GO:0044283 small molecule biosynthetic process
1.24 7.21e-05 GO:0071840 cellular component organization or biogenesis
1.65 7.50e-05 GO:0030001 metal ion transport
1.58 7.77e-05 GO:0048878 chemical homeostasis
1.80 1.01e-04 GO:0044271 cellular nitrogen compound biosynthetic process
3.16 1.09e-04 GO:0006826 iron ion transport
1.74 1.43e-04 GO:0006066 alcohol metabolic process
1.48 1.48e-04 GO:0051649 establishment of localization in cell
3.27 1.75e-04 GO:0034329 cell junction assembly
1.68 2.30e-04 GO:0061024 membrane organization
1.50 2.31e-04 GO:0051049 regulation of transport
1.46 2.54e-04 GO:2000026 regulation of multicellular organismal development
2.09 3.32e-04 GO:0071705 nitrogen compound transport
1.67 3.49e-04 GO:0016044 cellular membrane organization
1.44 4.11e-04 GO:0042127 regulation of cell proliferation
1.35 4.58e-04 GO:0009653 anatomical structure morphogenesis
1.41 5.05e-04 GO:0010941 regulation of cell death
2.66 5.76e-04 GO:0055123 digestive system development
3.51 6.50e-04 GO:0034976 response to endoplasmic reticulum stress
1.75 7.08e-04 GO:0035295 tube development
1.53 7.08e-04 GO:0012501 programmed cell death
1.53 7.10e-04 GO:0006915 apoptosis
1.87 7.40e-04 GO:0051056 regulation of small GTPase mediated signal transduction
1.41 1.08e-03 GO:0043067 regulation of programmed cell death
2.07 1.13e-03 GO:0030855 epithelial cell differentiation
1.18 1.26e-03 GO:0019222 regulation of metabolic process
1.40 1.28e-03 GO:0050793 regulation of developmental process
1.79 1.43e-03 GO:0002009 morphogenesis of an epithelium
1.80 1.43e-03 GO:0007264 small GTPase mediated signal transduction
2.12 1.52e-03 GO:0030811 regulation of nucleotide catabolic process
2.12 1.52e-03 GO:0033121 regulation of purine nucleotide catabolic process
1.27 1.74e-03 GO:0048869 cellular developmental process
1.64 1.77e-03 GO:0009719 response to endogenous stimulus
1.70 1.78e-03 GO:0044106 cellular amine metabolic process
3.94 1.82e-03 GO:0015988 energy coupled proton transport, against electrochemical gradient
3.94 1.82e-03 GO:0015991 ATP hydrolysis coupled proton transport
1.60 1.91e-03 GO:0034613 cellular protein localization
1.89 2.14e-03 GO:0046578 regulation of Ras protein signal transduction
1.55 2.27e-03 GO:0019725 cellular homeostasis
1.27 2.31e-03 GO:0030154 cell differentiation
2.07 2.54e-03 GO:0019216 regulation of lipid metabolic process
1.59 2.69e-03 GO:0070727 cellular macromolecule localization
1.39 2.74e-03 GO:0042981 regulation of apoptosis
1.43 2.75e-03 GO:0051128 regulation of cellular component organization
1.42 2.90e-03 GO:0022607 cellular component assembly
2.69 2.99e-03 GO:0048565 digestive tract development
1.95 3.07e-03 GO:0010035 response to inorganic substance
3.64 3.20e-03 GO:0015682 ferric iron transport
3.64 3.20e-03 GO:0033572 transferrin transport
2.17 3.46e-03 GO:0030324 lung development
1.52 3.97e-03 GO:0071844 cellular component assembly at cellular level
1.50 4.25e-03 GO:0046907 intracellular transport
1.37 4.31e-03 GO:0010646 regulation of cell communication
1.60 4.36e-03 GO:0009308 amine metabolic process
1.46 4.88e-03 GO:0008219 cell death
1.57 4.98e-03 GO:0071310 cellular response to organic substance
2.14 5.43e-03 GO:0030323 respiratory tube development
1.46 5.49e-03 GO:0016265 death
1.63 5.54e-03 GO:0090066 regulation of anatomical structure size
1.33 5.88e-03 GO:0009056 catabolic process
1.36 6.07e-03 GO:0010033 response to organic substance
1.25 6.69e-03 GO:0071842 cellular component organization at cellular level
1.54 6.96e-03 GO:0048585 negative regulation of response to stimulus
2.49 7.64e-03 GO:0016485 protein processing
1.41 7.98e-03 GO:0048468 cell development
1.21 8.11e-03 GO:0019538 protein metabolic process
1.47 8.40e-03 GO:0007154 cell communication
2.20 8.63e-03 GO:0032970 regulation of actin filament-based process
1.59 8.73e-03 GO:0051338 regulation of transferase activity
1.87 9.01e-03 GO:0046486 glycerolipid metabolic process
2.21 9.63e-03 GO:0032956 regulation of actin cytoskeleton organization
1.69 9.64e-03 GO:0032787 monocarboxylic acid metabolic process
1.73 9.92e-03 GO:0006520 cellular amino acid metabolic process
2.10 1.18e-02 GO:0043087 regulation of GTPase activity
1.42 1.29e-02 GO:0045595 regulation of cell differentiation
1.61 1.37e-02 GO:0045859 regulation of protein kinase activity
1.47 1.41e-02 GO:0046483 heterocycle metabolic process
1.87 1.45e-02 GO:0008202 steroid metabolic process
1.59 1.45e-02 GO:0043549 regulation of kinase activity
2.08 1.46e-02 GO:0033124 regulation of GTP catabolic process
2.02 1.47e-02 GO:0015837 amine transport
2.60 1.59e-02 GO:0006818 hydrogen transport
2.36 1.69e-02 GO:0051604 protein maturation
2.01 1.79e-02 GO:0060541 respiratory system development
2.28 1.85e-02 GO:0006662 glycerol ether metabolic process
2.11 1.89e-02 GO:0010038 response to metal ion
1.89 1.93e-02 GO:0010817 regulation of hormone levels
1.33 2.02e-02 GO:0007399 nervous system development
1.45 2.13e-02 GO:0043085 positive regulation of catalytic activity
2.51 2.13e-02 GO:0046890 regulation of lipid biosynthetic process
1.07 2.18e-02 GO:0009987 cellular process
1.99 2.18e-02 GO:0050878 regulation of body fluid levels
1.59 2.42e-02 GO:0009968 negative regulation of signal transduction
1.84 2.76e-02 GO:0030155 regulation of cell adhesion
2.23 3.03e-02 GO:0018904 organic ether metabolic process
2.17 3.07e-02 GO:0070482 response to oxygen levels
2.64 3.11e-02 GO:0006518 peptide metabolic process
2.64 3.11e-02 GO:0006754 ATP biosynthetic process
1.40 3.42e-02 GO:0044093 positive regulation of molecular function
3.31 3.42e-02 GO:0007044 cell-substrate junction assembly
2.31 4.06e-02 GO:0071216 cellular response to biotic stimulus
2.54 4.22e-02 GO:0015992 proton transport
1.77 4.37e-02 GO:0071495 cellular response to endogenous stimulus

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.34 2.08e-51 GO:0005737 cytoplasm
1.41 5.46e-40 GO:0044444 cytoplasmic part
1.21 4.29e-36 GO:0005622 intracellular
1.21 6.71e-33 GO:0044424 intracellular part
1.10 3.37e-20 GO:0005623 cell
1.10 3.37e-20 GO:0044464 cell part
1.72 1.11e-19 GO:0031090 organelle membrane
1.19 1.78e-19 GO:0043226 organelle
1.19 6.27e-19 GO:0043229 intracellular organelle
1.19 4.39e-17 GO:0043227 membrane-bounded organelle
1.19 1.13e-16 GO:0043231 intracellular membrane-bounded organelle
1.18 8.55e-15 GO:0016020 membrane
1.49 1.71e-14 GO:0044459 plasma membrane part
1.60 1.63e-13 GO:0000267 cell fraction
1.74 3.49e-13 GO:0012505 endomembrane system
1.62 1.36e-12 GO:0005783 endoplasmic reticulum
1.65 3.99e-12 GO:0005626 insoluble fraction
1.29 4.27e-12 GO:0071944 cell periphery
2.32 5.54e-12 GO:0045177 apical part of cell
1.63 1.08e-11 GO:0005794 Golgi apparatus
1.29 1.54e-11 GO:0005886 plasma membrane
2.51 2.60e-11 GO:0016324 apical plasma membrane
1.64 3.97e-11 GO:0005624 membrane fraction
1.76 1.26e-10 GO:0030054 cell junction
2.02 3.17e-09 GO:0042598 vesicular fraction
2.03 4.17e-09 GO:0005792 microsome
2.21 4.91e-09 GO:0005911 cell-cell junction
2.09 5.71e-09 GO:0042175 nuclear membrane-endoplasmic reticulum network
2.03 5.84e-09 GO:0044432 endoplasmic reticulum part
2.10 8.36e-09 GO:0005789 endoplasmic reticulum membrane
2.92 1.40e-08 GO:0016327 apicolateral plasma membrane
1.61 1.74e-08 GO:0031982 vesicle
2.84 1.21e-07 GO:0043296 apical junction complex
1.22 1.53e-07 GO:0044422 organelle part
1.22 2.82e-07 GO:0044446 intracellular organelle part
1.58 6.23e-07 GO:0031410 cytoplasmic vesicle
1.66 8.72e-07 GO:0031988 membrane-bounded vesicle
1.15 1.45e-06 GO:0044425 membrane part
1.85 3.28e-06 GO:0005743 mitochondrial inner membrane
1.82 4.56e-06 GO:0019866 organelle inner membrane
2.72 1.03e-05 GO:0005923 tight junction
2.72 1.03e-05 GO:0070160 occluding junction
1.35 1.06e-05 GO:0005739 mitochondrion
1.98 1.57e-05 GO:0016323 basolateral plasma membrane
1.35 2.34e-05 GO:0005829 cytosol
1.81 2.96e-05 GO:0048471 perinuclear region of cytoplasm
1.61 3.43e-05 GO:0016023 cytoplasmic membrane-bounded vesicle
2.08 3.89e-05 GO:0031252 cell leading edge
2.22 1.14e-04 GO:0005912 adherens junction
1.41 1.39e-04 GO:0044421 extracellular region part
2.14 1.63e-04 GO:0031300 intrinsic to organelle membrane
1.63 2.28e-04 GO:0031966 mitochondrial membrane
2.22 2.28e-04 GO:0031301 integral to organelle membrane
1.61 2.77e-04 GO:0005768 endosome
1.36 4.66e-04 GO:0042995 cell projection
2.08 6.17e-04 GO:0070161 anchoring junction
1.48 8.74e-04 GO:0031967 organelle envelope
1.58 9.75e-04 GO:0005740 mitochondrial envelope
1.30 1.08e-03 GO:0005856 cytoskeleton
1.47 1.18e-03 GO:0031975 envelope
2.21 2.57e-03 GO:0031253 cell projection membrane
1.68 2.76e-03 GO:0044431 Golgi apparatus part
3.14 2.80e-03 GO:0016469 proton-transporting two-sector ATPase complex
1.48 2.90e-03 GO:0044429 mitochondrial part
1.90 2.99e-03 GO:0012506 vesicle membrane
1.41 4.37e-03 GO:0005615 extracellular space
1.65 7.38e-03 GO:0005773 vacuole
2.04 9.37e-03 GO:0044420 extracellular matrix part
1.85 1.10e-02 GO:0030135 coated vesicle
3.11 1.18e-02 GO:0005793 ER-Golgi intermediate compartment
2.34 1.19e-02 GO:0001726 ruffle
2.60 2.20e-02 GO:0030176 integral to endoplasmic reticulum membrane
2.67 2.21e-02 GO:0005913 cell-cell adherens junction
1.57 2.32e-02 GO:0031012 extracellular matrix
1.87 2.38e-02 GO:0030136 clathrin-coated vesicle
1.61 2.65e-02 GO:0015629 actin cytoskeleton
2.43 2.76e-02 GO:0005903 brush border
1.83 2.85e-02 GO:0030659 cytoplasmic vesicle membrane
1.81 2.85e-02 GO:0044433 cytoplasmic vesicle part
2.31 3.12e-02 GO:0031227 intrinsic to endoplasmic reticulum membrane
1.45 3.34e-02 GO:0045202 synapse
2.02 3.64e-02 GO:0019898 extrinsic to membrane
1.59 3.73e-02 GO:0005578 proteinaceous extracellular matrix
1.99 3.84e-02 GO:0005777 peroxisome
1.99 3.84e-02 GO:0042579 microbody

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.19 1.20e-26 GO:0005488 binding
1.32 4.43e-26 GO:0005515 protein binding
1.29 2.24e-18 GO:0003824 catalytic activity
2.44 1.49e-10 GO:0022890 inorganic cation transmembrane transporter activity
1.99 4.83e-08 GO:0022804 active transmembrane transporter activity
1.57 5.52e-08 GO:0019899 enzyme binding
1.74 7.48e-08 GO:0008092 cytoskeletal protein binding
1.84 8.94e-08 GO:0008289 lipid binding
1.25 1.07e-07 GO:0043167 ion binding
1.25 1.53e-07 GO:0043169 cation binding
2.55 2.64e-07 GO:0046873 metal ion transmembrane transporter activity
2.03 5.00e-07 GO:0005083 small GTPase regulator activity
1.48 5.40e-07 GO:0005215 transporter activity
1.24 5.49e-07 GO:0046872 metal ion binding
1.31 6.08e-07 GO:0016787 hydrolase activity
1.53 9.79e-07 GO:0030234 enzyme regulator activity
1.51 2.76e-06 GO:0022857 transmembrane transporter activity
1.55 6.94e-06 GO:0016491 oxidoreductase activity
1.85 1.54e-05 GO:0003779 actin binding
1.47 1.61e-05 GO:0022892 substrate-specific transporter activity
1.63 1.80e-05 GO:0005509 calcium ion binding
2.11 2.37e-05 GO:0015291 secondary active transmembrane transporter activity
1.72 2.40e-05 GO:0030695 GTPase regulator activity
1.50 3.32e-05 GO:0022891 substrate-specific transmembrane transporter activity
1.51 5.50e-05 GO:0046983 protein dimerization activity
1.69 5.99e-05 GO:0060589 nucleoside-triphosphatase regulator activity
2.18 7.63e-05 GO:0015077 monovalent inorganic cation transmembrane transporter activity
1.85 1.59e-04 GO:0048037 cofactor binding
1.48 5.82e-04 GO:0015075 ion transmembrane transporter activity
1.44 6.28e-04 GO:0042802 identical protein binding
1.29 7.20e-04 GO:0046914 transition metal ion binding
1.54 7.60e-04 GO:0019904 protein domain specific binding
4.23 8.68e-04 GO:0019829 cation-transporting ATPase activity
1.55 1.19e-03 GO:0008324 cation transmembrane transporter activity
2.65 2.80e-03 GO:0042625 ATPase activity, coupled to transmembrane movement of ions
2.37 8.30e-03 GO:0015078 hydrogen ion transmembrane transporter activity
5.98 9.83e-03 GO:0050998 nitric-oxide synthase binding
1.84 1.09e-02 GO:0005543 phospholipid binding
1.50 1.14e-02 GO:0042803 protein homodimerization activity
2.05 1.23e-02 GO:0015293 symporter activity
1.44 1.42e-02 GO:0008233 peptidase activity
3.19 2.82e-02 GO:0046915 transition metal ion transmembrane transporter activity
2.15 3.02e-02 GO:0030165 PDZ domain binding
1.27 3.32e-02 GO:0008270 zinc ion binding
2.13 3.78e-02 GO:0043492 ATPase activity, coupled to movement of substances
1.74 4.97e-02 GO:0008236 serine-type peptidase activity