Motif ID: SOX17.p2

Z-value: 1.591


Transcription factors associated with SOX17.p2:

Gene SymbolEntrez IDGene Name
Sox17 20671 SRY-box containing gene 17

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox17chr1_-_4486443-0.402.3e-08Click!


Activity profile for motif SOX17.p2.

activity profile for motif SOX17.p2


Sorted Z-values histogram for motif SOX17.p2

Sorted Z-values for motif SOX17.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX17.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_11482121 22.996 NM_029499
 Ms4a4c
membrane-spanning 4-domains, subfamily A, member 4C
chr4_+_134024234 20.988 NM_019641
 Stmn1
stathmin 1
chr17_-_51878720 18.853 Satb1
special AT-rich sequence binding protein 1
chr7_-_52622323 16.901


chr16_-_17125198 15.123 NM_183287
 2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr16_+_52031704 14.738 Cblb
Casitas B-lineage lymphoma b
chr9_-_70269246 14.389 Ccnb2
cyclin B2
chr11_+_68859125 13.779 NM_011496
 Aurkb
aurora kinase B
chr7_-_80703275 13.592 1810026B05Rik
RIKEN cDNA 1810026B05 gene
chr1_+_34516650 13.443 Ptpn18
protein tyrosine phosphatase, non-receptor type 18
chr6_+_124780226 12.964 Cdca3
cell division cycle associated 3
chr1_+_34516590 12.873 NM_011206
 Ptpn18
protein tyrosine phosphatase, non-receptor type 18
chr13_-_101556356 12.673 NM_172301
 Ccnb1
cyclin B1
chr6_+_124780193 12.057 NM_013538
 Cdca3
cell division cycle associated 3
chr8_-_13677450 11.776 NM_009025
 Rasa3
RAS p21 protein activator 3
chr11_+_23156022 11.581 NM_001035226
NM_134014
 Xpo1

exportin 1, CRM1 homolog (yeast)

chr3_-_107135939 11.246 NM_001045807
 Rbm15
RNA binding motif protein 15
chr11_-_116274264 11.060 NM_027258
 Rnf157
ring finger protein 157
chr11_+_11586215 11.049 NM_001025597
NM_009578
 Ikzf1

IKAROS family zinc finger 1

chr4_-_151851624 10.832 Kcnab2
potassium voltage-gated channel, shaker-related subfamily, beta member 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 91 entries
Enrichment   P-value GO Accession GO Term
2.13 1.38e-04 GO:0030900 forebrain development
2.07 2.92e-05 GO:0007283 spermatogenesis
2.07 2.92e-05 GO:0048232 male gamete generation
2.05 4.67e-02 GO:0006260 DNA replication
1.95 5.19e-03 GO:0048285 organelle fission
1.95 7.92e-03 GO:0000280 nuclear division
1.95 7.92e-03 GO:0007067 mitosis
1.94 6.87e-03 GO:0000087 M phase of mitotic cell cycle
1.88 1.23e-04 GO:0007276 gamete generation
1.84 8.00e-04 GO:0007420 brain development
1.80 2.15e-03 GO:0000279 M phase
1.74 1.78e-02 GO:0016568 chromatin modification
1.71 2.48e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.70 1.93e-06 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.70 2.14e-06 GO:0010629 negative regulation of gene expression
1.70 3.73e-03 GO:0019953 sexual reproduction
1.70 2.60e-02 GO:0002520 immune system development
1.69 1.02e-19 GO:0006351 transcription, DNA-dependent
1.69 1.40e-19 GO:0032774 RNA biosynthetic process
1.69 5.59e-04 GO:0051276 chromosome organization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 26 entries
Enrichment   P-value GO Accession GO Term
2.15 5.05e-03 GO:0000775 chromosome, centromeric region
2.06 1.92e-04 GO:0000228 nuclear chromosome
2.03 1.91e-03 GO:0044454 nuclear chromosome part
1.73 1.80e-04 GO:0044427 chromosomal part
1.71 1.09e-04 GO:0005694 chromosome
1.61 2.83e-04 GO:0015630 microtubule cytoskeleton
1.56 2.51e-07 GO:0005654 nucleoplasm
1.56 2.08e-04 GO:0044451 nucleoplasm part
1.54 2.19e-10 GO:0031981 nuclear lumen
1.51 1.71e-11 GO:0044428 nuclear part
1.44 8.93e-32 GO:0005634 nucleus
1.41 6.63e-07 GO:0031974 membrane-enclosed lumen
1.41 6.77e-07 GO:0070013 intracellular organelle lumen
1.41 8.15e-07 GO:0043233 organelle lumen
1.29 2.55e-02 GO:0005856 cytoskeleton
1.28 1.76e-04 GO:0043228 non-membrane-bounded organelle
1.28 1.76e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.18 1.51e-13 GO:0043229 intracellular organelle
1.18 2.13e-13 GO:0043226 organelle
1.18 2.08e-11 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 17 of 17 entries
Enrichment   P-value GO Accession GO Term
1.99 3.53e-06 GO:0016564 transcription repressor activity
1.85 2.54e-12 GO:0001071 nucleic acid binding transcription factor activity
1.85 2.54e-12 GO:0003700 sequence-specific DNA binding transcription factor activity
1.85 2.64e-02 GO:0003682 chromatin binding
1.79 6.36e-13 GO:0030528 transcription regulator activity
1.71 4.22e-07 GO:0043565 sequence-specific DNA binding
1.61 1.37e-16 GO:0003677 DNA binding
1.55 1.43e-09 GO:0008270 zinc ion binding
1.52 6.81e-19 GO:0003676 nucleic acid binding
1.45 4.99e-08 GO:0046914 transition metal ion binding
1.29 3.74e-02 GO:0005524 ATP binding
1.27 2.08e-03 GO:0000166 nucleotide binding
1.20 2.81e-03 GO:0046872 metal ion binding
1.20 3.05e-03 GO:0043167 ion binding
1.20 3.47e-03 GO:0043169 cation binding
1.15 8.29e-12 GO:0005488 binding
1.15 1.17e-03 GO:0005515 protein binding