Motif ID: SOX2.p2

Z-value: 1.469


Transcription factors associated with SOX2.p2:

Gene SymbolEntrez IDGene Name
Sox2 20674 SRY-box containing gene 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox2chr3_+_345489160.402.6e-08Click!


Activity profile for motif SOX2.p2.

activity profile for motif SOX2.p2


Sorted Z-values histogram for motif SOX2.p2

Sorted Z-values for motif SOX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_120058842 48.487 NM_001039364
NM_001039365
NM_008614
 Mobp


myelin-associated oligodendrocytic basic protein


chr17_-_51878720 30.302 Satb1
special AT-rich sequence binding protein 1
chr12_-_73337534 27.861 Rtn1
reticulon 1
chr18_-_43219062 23.566 NM_028392
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr18_+_37157533 20.873 NM_138661
 Pcdha9
protocadherin alpha 9
chrX_+_155897136 20.371 Mtap7d2
MAP7 domain containing 2
chrX_+_132424640 19.898 Bhlhb9
basic helix-loop-helix domain containing, class B9
chr17_-_90436488 19.059 Nrxn1
neurexin I
chr2_-_170232008 17.517 Bcas1
breast carcinoma amplified sequence 1
chr18_-_23197156 17.084 NM_001161483
 Nol4
nucleolar protein 4
chrX_+_155897056 16.717 Mtap7d2
MAP7 domain containing 2
chrX_-_149078963 16.214 Shroom2
shroom family member 2
chr18_+_37120093 16.075 NM_009959
 Pcdha5
protocadherin alpha 5
chr12_+_91570569 15.454 Nrxn3
neurexin III
chr5_+_67067477 14.810 Uchl1
ubiquitin carboxy-terminal hydrolase L1
chr18_+_82723920 14.755 Mbp
myelin basic protein
chr9_-_49311823 14.704 Ncam1
neural cell adhesion molecule 1
chr18_+_37112301 14.460 NM_001174154
NM_007766
 Pcdha4-g
Pcdha4
protocadherin alpha 4-gamma
protocadherin alpha 4
chr10_-_30375572 14.288 NM_001111267
 Ncoa7
nuclear receptor coactivator 7
chr18_+_37127284 14.093 NM_007767
 Pcdha6
protocadherin alpha 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 49 entries
Enrichment   P-value GO Accession GO Term
2.21 1.58e-02 GO:0007411 axon guidance
2.19 9.39e-06 GO:0007409 axonogenesis
2.17 1.33e-06 GO:0048812 neuron projection morphogenesis
2.10 2.29e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
2.07 1.90e-07 GO:0031175 neuron projection development
2.06 9.22e-07 GO:0048858 cell projection morphogenesis
2.02 2.47e-06 GO:0032990 cell part morphogenesis
1.99 2.44e-02 GO:0010975 regulation of neuron projection development
1.93 2.27e-07 GO:0048666 neuron development
1.86 2.30e-03 GO:0045664 regulation of neuron differentiation
1.84 9.24e-04 GO:0000904 cell morphogenesis involved in differentiation
1.79 1.07e-06 GO:0030182 neuron differentiation
1.78 1.74e-02 GO:0008380 RNA splicing
1.77 8.14e-05 GO:0000902 cell morphogenesis
1.77 2.93e-03 GO:0050767 regulation of neurogenesis
1.74 4.39e-05 GO:0030030 cell projection organization
1.74 7.56e-03 GO:0016568 chromatin modification
1.71 1.76e-08 GO:0048699 generation of neurons
1.69 6.24e-03 GO:0006325 chromatin organization
1.68 3.34e-08 GO:0022008 neurogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 24 entries
Enrichment   P-value GO Accession GO Term
8.05 1.34e-02 GO:0001520 outer dense fiber
5.12 4.29e-02 GO:0071565 nBAF complex
2.96 4.78e-02 GO:0005720 nuclear heterochromatin
2.48 4.38e-03 GO:0016585 chromatin remodeling complex
2.38 1.40e-02 GO:0030426 growth cone
2.33 2.17e-02 GO:0014069 postsynaptic density
2.30 2.68e-02 GO:0030427 site of polarized growth
1.98 2.72e-07 GO:0044456 synapse part
1.82 1.19e-07 GO:0045202 synapse
1.77 4.21e-03 GO:0005874 microtubule
1.76 5.35e-03 GO:0030424 axon
1.64 2.65e-05 GO:0043005 neuron projection
1.63 1.87e-03 GO:0044463 cell projection part
1.62 7.47e-05 GO:0015630 microtubule cytoskeleton
1.60 2.99e-02 GO:0044297 cell body
1.58 1.17e-07 GO:0044430 cytoskeletal part
1.50 2.01e-03 GO:0030054 cell junction
1.48 4.29e-06 GO:0042995 cell projection
1.44 3.44e-07 GO:0005856 cytoskeleton
1.27 9.53e-05 GO:0043228 non-membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
6.90 1.69e-02 GO:0008331 high voltage-gated calcium channel activity
1.82 2.48e-02 GO:0003682 chromatin binding
1.50 1.88e-02 GO:0019904 protein domain specific binding
1.36 3.21e-02 GO:XXXXXXX unannotated
1.34 2.01e-03 GO:0008270 zinc ion binding
1.31 7.69e-04 GO:0003677 DNA binding
1.28 1.67e-05 GO:0003676 nucleic acid binding
1.14 1.89e-03 GO:0005515 protein binding