Motif ID: SP1.p2

Z-value: 1.730


Transcription factors associated with SP1.p2:

Gene SymbolEntrez IDGene Name
Sp1 20683 trans-acting transcription factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sp1chr15_+_1022367090.417.4e-09Click!


Activity profile for motif SP1.p2.

activity profile for motif SP1.p2


Sorted Z-values histogram for motif SP1.p2

Sorted Z-values for motif SP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_24393435 20.146 NM_178665
Lpp
LIM domain containing preferred translocation partner in lipoma
chr2_-_76486033 18.493 NM_011871
Prkra
protein kinase, interferon inducible double stranded RNA dependent activator
chr3_+_21975544 18.102 NM_030732
Tbl1xr1
transducin (beta)-like 1X-linked receptor 1
chr16_-_22163035 17.545 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr15_+_102236709 17.535 NM_013672
Sp1
trans-acting transcription factor 1
chr1_-_155179844 17.290 NM_010683
Lamc1
laminin, gamma 1
chr2_-_76486065 16.009 Prkra
protein kinase, interferon inducible double stranded RNA dependent activator
chr4_-_40800983 15.159 B4galt1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr4_-_16090542 15.092 NM_138952
Ripk2
receptor (TNFRSF)-interacting serine-threonine kinase 2
chr4_-_106925932 15.032 Lrrc42
leucine rich repeat containing 42
chr17_+_31701700 14.893 NM_016670
Pknox1
Pbx/knotted 1 homeobox
chr4_-_106926041 14.304 NM_029985
Lrrc42
leucine rich repeat containing 42
chr1_-_82287990 13.993 NM_010570
Irs1
insulin receptor substrate 1
chr2_-_26788845 13.848 Surf4
surfeit gene 4
chr19_+_7049639 13.824 Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr6_+_42299820 13.789 NM_011777
Zyx
zyxin
chr19_+_7049425 13.572 NM_008889
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr17_+_35196041 13.504 Ddah2
dimethylarginine dimethylaminohydrolase 2
chr17_-_71201055 13.434 NM_001164075
Tgif1
TGFB-induced factor homeobox 1
chr4_-_134828699 13.281 Clic4
chloride intracellular channel 4 (mitochondrial)
chr4_-_40800995 13.238 NM_022305
B4galt1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr17_+_35195979 13.143 NM_001190449
NM_016765
Ddah2

dimethylarginine dimethylaminohydrolase 2

chr14_-_52634206 13.132 Zfp219
zinc finger protein 219
chr7_+_28233013 12.779 Blvrb
biliverdin reductase B (flavin reductase (NADPH))
chr7_+_28232980 12.714 NM_144923
Blvrb
biliverdin reductase B (flavin reductase (NADPH))
chr6_+_124613114 12.642 NM_145130
Lpcat3
lysophosphatidylcholine acyltransferase 3
chr18_+_70727897 12.185 NM_010773
Mbd2
methyl-CpG binding domain protein 2
chr1_-_52557130 12.114 NM_008667
Nab1
Ngfi-A binding protein 1
chr12_+_8778260 12.041 Sdc1
syndecan 1
chr5_-_114358647 11.985 NM_011779
Coro1c
coronin, actin binding protein 1C
chr9_-_122203459 11.960 Ano10
anoctamin 10
chr16_+_4594742 11.952 Glis2
GLIS family zinc finger 2
chr18_+_83084023 11.890 NM_001177464
Zfp516
zinc finger protein 516
chr11_-_109472715 11.813 Wipi1
WD repeat domain, phosphoinositide interacting 1
chr2_+_18598644 11.604 NM_007552
Bmi1
Bmi1 polycomb ring finger oncogene
chr11_-_115971521 11.313 Trim47
tripartite motif-containing 47
chr11_-_62462024 11.275 NM_198861
BC046404
cDNA sequence BC046404
chr1_-_36615225 11.202 NM_001126047
Sema4c
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr10_+_57786213 11.137 NM_026148
Lims1
LIM and senescent cell antigen-like domains 1
chr9_-_107612238 11.120 Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr4_-_151370212 11.056 NM_172705
Phf13
PHD finger protein 13
chr8_-_123112974 11.034 NM_178856
Gins2
GINS complex subunit 2 (Psf2 homolog)
chr7_+_148661329 10.958 Tspan4
tetraspanin 4
chr12_-_73186299 10.927 NM_026038
2810055F11Rik
RIKEN cDNA 2810055F11 gene
chr7_+_148661138 10.917 NM_053082
Tspan4
tetraspanin 4
chr11_-_115873976 10.887 NM_016905
Galk1
galactokinase 1
chr1_+_75378688 10.815 NM_001085371
Speg
SPEG complex locus
chrX_-_71491851 10.799 NM_010227
Flna
filamin, alpha
chr2_+_117937623 10.793 NM_011580
Thbs1
thrombospondin 1
chr17_-_45732442 10.717 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr15_+_78813475 10.691 NM_001024716
Triobp
TRIO and F-actin binding protein
chrX_+_74756540 10.660 NM_020601
Tbl1x
transducin (beta)-like 1 X-linked
chr16_+_4594703 10.645 NM_031184
Glis2
GLIS family zinc finger 2
chr1_-_36614888 10.629 Sema4c
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr11_-_109472694 10.573 Wipi1
WD repeat domain, phosphoinositide interacting 1
chr11_+_20531941 10.570 NM_001038625
Sertad2
SERTA domain containing 2
chr8_-_123112925 10.442 Gins2
GINS complex subunit 2 (Psf2 homolog)
chr12_+_34642676 10.332 Twist1
twist homolog 1 (Drosophila)
chr7_+_26471968 10.242 NM_011577
Tgfb1
transforming growth factor, beta 1
chr4_-_128925666 10.211 NM_001033189
C77080
expressed sequence C77080
chr4_-_16090763 10.207 Ripk2
receptor (TNFRSF)-interacting serine-threonine kinase 2
chr11_+_117127516 10.177 NM_001113487
Sept9
septin 9
chr7_+_52273317 10.149 NM_009101
Rras
Harvey rat sarcoma oncogene, subgroup R
chr5_-_141306258 10.112 NM_010302
Gna12
guanine nucleotide binding protein, alpha 12
chr7_+_3290587 10.031 Myadm
myeloid-associated differentiation marker
chrX_-_136406046 9.961 NM_001193309
NM_029413
Morc4

microrchidia 4

chrX_+_139115908 9.960 NM_177592
Tmem164
transmembrane protein 164
chr12_+_86940285 9.937 NM_030887
Jdp2
Jun dimerization protein 2
chr2_-_26789021 9.933 NM_011512
Surf4
surfeit gene 4
chr13_-_49311308 9.851 NM_026738
1110007C09Rik
RIKEN cDNA 1110007C09 gene
chr3_+_104591946 9.817 NM_007484
Rhoc
ras homolog gene family, member C
chr8_+_131209614 9.636 Itgb1
integrin beta 1 (fibronectin receptor beta)
chrX_+_74756332 9.567 Tbl1x
transducin (beta)-like 1 X-linked
chr4_-_55545211 9.519 Klf4
Kruppel-like factor 4 (gut)
chr4_+_140258090 9.500 Rcc2
regulator of chromosome condensation 2
chr14_+_21748602 9.345 Vcl
vinculin
chr19_+_38129500 9.306 NM_028293
NM_001164362
NM_028760
Cep55


centrosomal protein 55


chr2_-_143836838 9.285 NM_024281
NM_133626
Rrbp1

ribosome binding protein 1

chr4_+_111392665 9.232 Spata6
spermatogenesis associated 6
chr2_+_154616830 9.208 NM_001139511
NM_001139512
NM_001139513
NM_023130
Raly



hnRNP-associated with lethal yellow



chr2_+_156665812 9.177 NM_173396
Tgif2
TGFB-induced factor homeobox 2
chr5_-_122286849 9.175 Sh2b3
SH2B adaptor protein 3
chr7_-_52071930 9.171 Atf5
activating transcription factor 5
chr17_-_71200462 9.142 NM_009372
Tgif1
TGFB-induced factor homeobox 1
chr13_+_72766425 9.121 NM_010574
Irx2
Iroquois related homeobox 2 (Drosophila)
chr9_-_122203483 9.059 NM_133979
Ano10
anoctamin 10
chr11_-_115971327 9.043 NM_172570
Trim47
tripartite motif-containing 47
chr10_-_80893737 9.025 Nfic
nuclear factor I/C
chr12_-_86113948 9.019 NM_023409
Npc2
Niemann Pick type C2
chr15_+_78813524 8.978 Triobp
TRIO and F-actin binding protein
chr5_+_145016060 8.968 NM_018772
Bri3
brain protein I3
chr16_-_17928207 8.916 Slc25a1
solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
chr19_-_5424694 8.902 Drap1
Dr1 associated protein 1 (negative cofactor 2 alpha)
chr5_+_53132801 8.864 NM_025951
NM_028744
Pi4k2b

phosphatidylinositol 4-kinase type 2 beta

chr12_+_111685516 8.837 Ppp2r5c
protein phosphatase 2, regulatory subunit B (B56), gamma isoform
chrX_-_147247483 8.788 Maged2
melanoma antigen, family D, 2
chr17_-_35653683 8.757 NM_001163763
NM_001163764
NM_025674
Tcf19


transcription factor 19


chr12_-_86113816 8.701 Npc2
Niemann Pick type C2
chr13_-_104899571 8.699 NM_029447
Nln
neurolysin (metallopeptidase M3 family)
chr1_-_157659936 8.699 NM_001024945
NM_023268
Qsox1

quiescin Q6 sulfhydryl oxidase 1

chr4_-_55545337 8.674 NM_010637
Klf4
Kruppel-like factor 4 (gut)
chr11_+_75469516 8.646 NM_001080775
Myo1c
myosin IC
chr11_+_20443168 8.567 NM_021372
Sertad2
SERTA domain containing 2
chr4_+_111392628 8.536 Spata6
spermatogenesis associated 6
chr5_-_65826956 8.531 Ugdh
UDP-glucose dehydrogenase
chr13_+_54890763 8.516 NM_028841
Tspan17
tetraspanin 17
chr11_-_70468019 8.475 Pfn1
profilin 1
chr15_+_31154178 8.457 Dap
death-associated protein
chr7_-_134170532 8.455 Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr8_+_131209680 8.407 Itgb1
integrin beta 1 (fibronectin receptor beta)
chr18_+_64500017 8.401 NM_194268
Onecut2
one cut domain, family member 2
chr17_-_45736533 8.393 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr4_-_134828503 8.379 NM_013885
Clic4
chloride intracellular channel 4 (mitochondrial)
chr14_-_32643594 8.374 NM_001024604
Ankrd28
ankyrin repeat domain 28
chr7_+_3290622 8.329 Myadm
myeloid-associated differentiation marker
chr7_-_149763980 8.318 H19
H19 fetal liver mRNA
chr3_+_68808879 8.276 NM_133786
Smc4
structural maintenance of chromosomes 4
chr5_+_53132872 8.240 Pi4k2b
phosphatidylinositol 4-kinase type 2 beta
chr10_+_126415973 8.226 Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr15_-_35085306 8.206 NM_019635
Stk3
serine/threonine kinase 3 (Ste20, yeast homolog)
chr9_+_106356125 8.194 NM_021567
Pcbp4
poly(rC) binding protein 4
chr2_-_60800904 8.148 Rbms1
RNA binding motif, single stranded interacting protein 1
chr7_+_37483093 8.138 NM_172298
Tshz3
teashirt zinc finger family member 3
chr8_-_73905790 8.135 NM_010150
Nr2f6
nuclear receptor subfamily 2, group F, member 6
chr11_-_77326748 8.074 NM_001024920
Trp53i13
transformation related protein 53 inducible protein 13
chr18_-_89063572 8.051 NM_018821
Socs6
suppressor of cytokine signaling 6
chr6_+_42300005 8.036 Zyx
zyxin
chr5_-_122286761 7.988 NM_008507
Sh2b3
SH2B adaptor protein 3
chr17_+_45823255 7.987 NM_026732
Mrpl14
mitochondrial ribosomal protein L14
chr14_+_21748646 7.972 NM_009502
Vcl
vinculin
chrX_-_159326220 7.965 NM_025932
Syap1
synapse associated protein 1
chr8_-_35040236 7.964 Rbpms
RNA binding protein gene with multiple splicing
chr16_+_92058498 7.902 NM_080456
NM_017391
Mrps6
Slc5a3
mitochondrial ribosomal protein S6
solute carrier family 5 (inositol transporters), member 3
chr12_+_8778201 7.900 NM_011519
Sdc1
syndecan 1
chr6_-_97155541 7.878 NM_001111106
NM_011666
Uba3

ubiquitin-like modifier activating enzyme 3

chr19_+_5474686 7.860 NM_021474
NM_001164352
Efemp2

epidermal growth factor-containing fibulin-like extracellular matrix protein 2

chr7_-_134852110 7.841 Bcl7c
B-cell CLL/lymphoma 7C
chr10_-_121534134 7.838 NM_153059
Tmem5
transmembrane protein 5
chr3_+_88336316 7.834 NM_001029890
Mex3a
mex3 homolog A (C. elegans)
chrX_-_147248183 7.812 Maged2
melanoma antigen, family D, 2
chr9_-_65427840 7.795 NM_153119
Plekho2
pleckstrin homology domain containing, family O member 2
chr2_+_143741243 7.748 Dstn
destrin
chr5_-_134932407 7.728 NM_001081462
NM_001081463
NM_001081464
NM_001081466
NM_001081467
NM_001081468
NM_001081469
NM_001081470
NM_020331
Gtf2ird1








general transcription factor II I repeat domain-containing 1








chr6_-_124867872 7.693 Ptms
parathymosin
chr5_-_65826969 7.679 NM_009466
Ugdh
UDP-glucose dehydrogenase
chr4_+_3866023 7.669 NM_001190323
NM_001190324
NM_001190322
NM_181391
Chchd7



coiled-coil-helix-coiled-coil-helix domain containing 7



chr15_+_78757148 7.649 NM_008495
Lgals1
lectin, galactose binding, soluble 1
chr16_+_58408609 7.642 NM_028523
Dcbld2
discoidin, CUB and LCCL domain containing 2
chr16_-_22163264 7.600 NM_183029
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr12_+_34642516 7.600 NM_011658
Twist1
twist homolog 1 (Drosophila)
chr7_-_52071027 7.577 NM_030693
Atf5
activating transcription factor 5
chr3_+_108186721 7.566 NM_001190161
NM_019976
Psrc1

proline/serine-rich coiled-coil 1

chr7_+_3646102 7.530 NM_024168
Tsen34
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr5_+_145875080 7.489 NM_023142
Arpc1b
actin related protein 2/3 complex, subunit 1B
chr11_-_74982551 7.489 Hic1
hypermethylated in cancer 1
chr4_-_43536296 7.466 Tpm2
tropomyosin 2, beta
chr9_-_31019412 7.408 Aplp2
amyloid beta (A4) precursor-like protein 2
chr7_-_108971734 7.395


chr15_+_98860321 7.386 NM_009448
Tuba1c
tubulin, alpha 1C
chr8_-_35040277 7.385 NM_001042674
NM_001042675
NM_019733
Rbpms


RNA binding protein gene with multiple splicing


chr12_+_33505307 7.369 Nampt
nicotinamide phosphoribosyltransferase
chr13_-_49311136 7.351 1110007C09Rik
RIKEN cDNA 1110007C09 gene
chr1_+_95375503 7.350 NM_001159717
NM_001159718
NM_010891
NM_001159719
Sept2



septin 2



chr19_+_4214263 7.338 Clcf1
cardiotrophin-like cytokine factor 1
chr7_-_52309439 7.325 Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr18_+_73732352 7.317 NM_001039214
Mex3c
mex3 homolog C (C. elegans)
chr19_-_5424856 7.287 NM_024176
Drap1
Dr1 associated protein 1 (negative cofactor 2 alpha)
chr1_-_75313930 7.252 NM_001110831
Dnpep
aspartyl aminopeptidase
chr19_-_5424751 7.248 Drap1
Dr1 associated protein 1 (negative cofactor 2 alpha)
chr19_+_5475020 7.234 Efemp2
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr17_+_64213350 7.223 Fert2
fer (fms/fps related) protein kinase, testis specific 2
chr9_-_88376937 7.200 NM_019666
NM_019796
Syncrip

synaptotagmin binding, cytoplasmic RNA interacting protein

chrX_-_71491736 7.158 Flna
filamin, alpha
chr14_-_26588341 7.135 NM_001101433
Zcchc24
zinc finger, CCHC domain containing 24
chr2_-_167174531 7.128 NM_019835
B4galt5
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
chr7_-_20334814 7.113 Pvrl2
poliovirus receptor-related 2
chr8_+_131209787 7.102 Itgb1
integrin beta 1 (fibronectin receptor beta)
chr2_-_91864276 7.087 NM_011957
Creb3l1
cAMP responsive element binding protein 3-like 1
chr9_+_72510153 7.054 NM_010890
Nedd4
neural precursor cell expressed, developmentally down-regulated 4
chr11_+_62462155 7.038 NM_175002
Mmgt2
membrane magnesium transporter 2
chr15_+_5093855 7.037 NM_001013367
Prkaa1
protein kinase, AMP-activated, alpha 1 catalytic subunit
chr15_+_61816895 7.020 NM_001177352
NM_001177353
NM_001177354
NM_010849
Myc



myelocytomatosis oncogene



chr5_+_73305509 7.020 NM_001113423
NM_153567
Slain2

SLAIN motif family, member 2

chr11_+_69794546 7.001 NM_026017
Ctdnep1
CTD nuclear envelope phosphatase 1
chr10_+_31033188 6.996 NM_027168
Hddc2
HD domain containing 2
chr7_+_147311582 6.993 NM_153783
Paox
polyamine oxidase (exo-N4-amino)
chr4_+_151648348 6.990 NM_178406
Gpr153
G protein-coupled receptor 153
chr6_+_28373521 6.978 NM_007480
Arf5
ADP-ribosylation factor 5
chr8_-_124431245 6.955 Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr7_-_134169938 6.950 NM_010772
Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr7_-_52347489 6.926 NM_026555
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chrX_-_35918177 6.922 Cul4b
cullin 4B
chr4_+_154937914 6.885 NM_001159637
Nadk
NAD kinase
chr10_+_126415772 6.874 NM_001113470
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr6_+_7795223 6.850 NM_052993
C1galt1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr4_-_3865501 6.842 NM_019969
Plag1
pleiomorphic adenoma gene 1
chr11_+_102465684 6.833 NM_020510
Fzd2
frizzled homolog 2 (Drosophila)
chr16_-_17928270 6.823 NM_153150
Slc25a1
solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
chr9_-_71959599 6.809 NM_011544
Tcf12
transcription factor 12
chr11_+_74433123 6.786 E130309D14Rik
RIKEN cDNA E130309D14 gene

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.27 7.16e-80 GO:0044237 cellular metabolic process
1.24 2.73e-77 GO:0008152 metabolic process
1.26 2.48e-72 GO:0044238 primary metabolic process
1.31 1.57e-57 GO:0019222 regulation of metabolic process
1.28 1.04e-55 GO:0044260 cellular macromolecule metabolic process
1.32 3.92e-52 GO:0031323 regulation of cellular metabolic process
1.32 8.33e-52 GO:0006807 nitrogen compound metabolic process
1.25 3.70e-51 GO:0043170 macromolecule metabolic process
1.32 1.93e-50 GO:0034641 cellular nitrogen compound metabolic process
1.31 4.41e-49 GO:0080090 regulation of primary metabolic process
1.33 1.47e-47 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32 2.83e-47 GO:0060255 regulation of macromolecule metabolic process
1.36 1.94e-46 GO:0010468 regulation of gene expression
1.34 2.36e-45 GO:0071840 cellular component organization or biogenesis
1.34 4.29e-45 GO:0016043 cellular component organization
1.37 6.74e-45 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.35 1.18e-44 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35 6.18e-44 GO:0051171 regulation of nitrogen compound metabolic process
1.32 1.94e-43 GO:0009058 biosynthetic process
1.32 3.36e-43 GO:0044249 cellular biosynthetic process
1.35 1.14e-42 GO:0010556 regulation of macromolecule biosynthetic process
1.34 6.74e-42 GO:0031326 regulation of cellular biosynthetic process
1.37 8.62e-42 GO:0051252 regulation of RNA metabolic process
1.33 2.51e-41 GO:0009889 regulation of biosynthetic process
1.38 3.00e-40 GO:0048523 negative regulation of cellular process
1.36 2.32e-39 GO:0006355 regulation of transcription, DNA-dependent
1.32 7.61e-39 GO:0048518 positive regulation of biological process
1.30 2.35e-38 GO:0032502 developmental process
1.35 3.89e-38 GO:0048519 negative regulation of biological process
1.34 1.42e-37 GO:0048522 positive regulation of cellular process
1.30 1.26e-35 GO:0007275 multicellular organismal development
1.31 6.09e-35 GO:0090304 nucleic acid metabolic process
1.34 1.23e-33 GO:0071841 cellular component organization or biogenesis at cellular level
1.35 5.74e-33 GO:0071842 cellular component organization at cellular level
1.32 1.28e-31 GO:0034645 cellular macromolecule biosynthetic process
1.30 1.76e-31 GO:0048856 anatomical structure development
1.32 2.41e-31 GO:0009059 macromolecule biosynthetic process
1.26 2.06e-29 GO:0051179 localization
1.30 5.64e-28 GO:0048731 system development
1.30 1.90e-27 GO:0016070 RNA metabolic process
1.35 8.87e-27 GO:0006351 transcription, DNA-dependent
1.35 1.07e-26 GO:0032774 RNA biosynthetic process
1.09 1.21e-25 GO:0009987 cellular process
1.38 2.88e-25 GO:0006996 organelle organization
1.27 9.21e-25 GO:0010467 gene expression
1.44 1.45e-24 GO:0009892 negative regulation of metabolic process
1.45 1.19e-23 GO:0010605 negative regulation of macromolecule metabolic process
1.45 1.35e-23 GO:0031324 negative regulation of cellular metabolic process
1.31 1.96e-23 GO:0030154 cell differentiation
1.30 9.32e-23 GO:0048869 cellular developmental process
1.25 2.94e-22 GO:0051234 establishment of localization
1.26 3.64e-22 GO:0006810 transport
1.37 7.93e-22 GO:0009653 anatomical structure morphogenesis
1.38 1.17e-21 GO:0010604 positive regulation of macromolecule metabolic process
1.35 2.25e-21 GO:0023051 regulation of signaling
1.39 4.34e-21 GO:0009966 regulation of signal transduction
1.33 9.30e-21 GO:0048583 regulation of response to stimulus
1.35 1.13e-20 GO:0009893 positive regulation of metabolic process
1.32 4.32e-20 GO:0044281 small molecule metabolic process
1.42 8.48e-20 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.32 1.03e-19 GO:0006464 protein modification process
1.49 1.14e-19 GO:0010558 negative regulation of macromolecule biosynthetic process
1.47 1.70e-19 GO:0009890 negative regulation of biosynthetic process
1.35 2.85e-19 GO:0031325 positive regulation of cellular metabolic process
1.30 3.82e-19 GO:0043412 macromolecule modification
1.47 4.08e-19 GO:0031327 negative regulation of cellular biosynthetic process
1.50 4.88e-19 GO:0010629 negative regulation of gene expression
1.49 7.74e-19 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.44 1.51e-18 GO:0010628 positive regulation of gene expression
1.30 1.86e-18 GO:0048513 organ development
1.32 6.85e-18 GO:0065009 regulation of molecular function
1.36 8.25e-18 GO:0007399 nervous system development
1.26 8.45e-18 GO:0044267 cellular protein metabolic process
1.36 1.09e-17 GO:0033036 macromolecule localization
1.49 7.36e-17 GO:0051253 negative regulation of RNA metabolic process
1.38 9.43e-17 GO:0051641 cellular localization
1.41 1.37e-16 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49 1.39e-16 GO:0045892 negative regulation of transcription, DNA-dependent
1.46 1.48e-16 GO:0051172 negative regulation of nitrogen compound metabolic process
1.41 1.77e-16 GO:0010557 positive regulation of macromolecule biosynthetic process
1.46 1.99e-16 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.44 2.81e-16 GO:0045893 positive regulation of transcription, DNA-dependent
1.43 2.81e-16 GO:0051254 positive regulation of RNA metabolic process
1.42 6.02e-16 GO:0009790 embryo development
1.37 9.29e-16 GO:0050793 regulation of developmental process
1.37 1.10e-15 GO:0008104 protein localization
1.41 1.22e-15 GO:0051128 regulation of cellular component organization
1.39 1.25e-15 GO:0051173 positive regulation of nitrogen compound metabolic process
1.22 1.47e-15 GO:0019538 protein metabolic process
1.42 5.16e-15 GO:0045595 regulation of cell differentiation
1.37 8.14e-15 GO:0031328 positive regulation of cellular biosynthetic process
1.37 1.45e-14 GO:0009891 positive regulation of biosynthetic process
1.53 3.44e-14 GO:0051726 regulation of cell cycle
1.46 4.68e-14 GO:0046907 intracellular transport
1.32 4.74e-14 GO:0009056 catabolic process
1.50 4.97e-14 GO:0072358 cardiovascular system development
1.50 4.97e-14 GO:0072359 circulatory system development
1.29 8.56e-14 GO:0051239 regulation of multicellular organismal process
1.34 9.06e-14 GO:0010646 regulation of cell communication
1.50 9.31e-14 GO:0009792 embryo development ending in birth or egg hatching
1.36 2.72e-13 GO:0042127 regulation of cell proliferation
1.32 2.97e-13 GO:0050790 regulation of catalytic activity
1.35 3.16e-13 GO:0032268 regulation of cellular protein metabolic process
1.49 7.89e-13 GO:0043009 chordate embryonic development
1.38 9.23e-13 GO:0045184 establishment of protein localization
1.34 9.24e-13 GO:0042981 regulation of apoptosis
1.33 1.38e-12 GO:0010941 regulation of cell death
1.34 1.45e-12 GO:0043067 regulation of programmed cell death
1.55 2.02e-12 GO:0009968 negative regulation of signal transduction
1.38 2.23e-12 GO:0015031 protein transport
1.36 2.62e-12 GO:0051649 establishment of localization in cell
1.36 2.99e-12 GO:0009888 tissue development
1.32 4.78e-12 GO:0035556 intracellular signal transduction
1.63 8.33e-12 GO:0007507 heart development
1.51 1.00e-11 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.32 1.06e-11 GO:0044248 cellular catabolic process
1.44 1.23e-11 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.52 1.54e-11 GO:0032583 regulation of gene-specific transcription
1.51 1.69e-11 GO:0010648 negative regulation of cell communication
1.50 2.58e-11 GO:0023057 negative regulation of signaling
1.35 2.80e-11 GO:2000026 regulation of multicellular organismal development
1.31 2.93e-11 GO:0051246 regulation of protein metabolic process
1.36 4.31e-11 GO:0007049 cell cycle
1.56 4.52e-11 GO:0035295 tube development
1.41 5.68e-11 GO:0009887 organ morphogenesis
1.31 1.09e-10 GO:0006793 phosphorus metabolic process
1.31 1.17e-10 GO:0006796 phosphate metabolic process
1.36 1.59e-10 GO:0048699 generation of neurons
1.49 2.71e-10 GO:0060284 regulation of cell development
1.34 3.78e-10 GO:0022008 neurogenesis
1.44 5.81e-10 GO:0048585 negative regulation of response to stimulus
1.56 6.19e-10 GO:0001701 in utero embryonic development
1.47 7.68e-10 GO:0040008 regulation of growth
1.22 8.20e-10 GO:0065008 regulation of biological quality
1.30 9.42e-10 GO:0044085 cellular component biogenesis
1.47 2.39e-09 GO:0060429 epithelium development
1.41 2.50e-09 GO:0051094 positive regulation of developmental process
1.52 2.53e-09 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.52 3.35e-09 GO:0016568 chromatin modification
1.42 4.23e-09 GO:0051276 chromosome organization
1.32 7.05e-09 GO:0048468 cell development
1.35 1.01e-08 GO:0016265 death
1.37 1.02e-08 GO:0016192 vesicle-mediated transport
1.37 1.08e-08 GO:0012501 programmed cell death
1.31 1.14e-08 GO:0022607 cellular component assembly
1.48 1.16e-08 GO:0048729 tissue morphogenesis
1.33 1.23e-08 GO:0044093 positive regulation of molecular function
1.47 1.55e-08 GO:0006325 chromatin organization
1.46 1.83e-08 GO:0045597 positive regulation of cell differentiation
1.36 2.09e-08 GO:0006915 apoptosis
1.28 2.53e-08 GO:0032879 regulation of localization
1.42 2.73e-08 GO:0070727 cellular macromolecule localization
1.34 2.97e-08 GO:0008219 cell death
1.52 3.27e-08 GO:0001568 blood vessel development
1.35 3.70e-08 GO:0033554 cellular response to stress
1.41 3.79e-08 GO:0006753 nucleoside phosphate metabolic process
1.41 3.79e-08 GO:0009117 nucleotide metabolic process
1.50 3.91e-08 GO:0001944 vasculature development
1.42 4.19e-08 GO:0034613 cellular protein localization
1.39 5.26e-08 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.36 7.13e-08 GO:0046483 heterocycle metabolic process
1.34 9.49e-08 GO:0019220 regulation of phosphate metabolic process
1.34 9.49e-08 GO:0051174 regulation of phosphorus metabolic process
1.46 1.12e-07 GO:0051960 regulation of nervous system development
1.55 1.14e-07 GO:0061061 muscle structure development
1.38 1.37e-07 GO:0048646 anatomical structure formation involved in morphogenesis
1.48 1.56e-07 GO:0050767 regulation of neurogenesis
1.51 2.42e-07 GO:0002009 morphogenesis of an epithelium
1.34 2.74e-07 GO:0042325 regulation of phosphorylation
1.47 3.30e-07 GO:0006886 intracellular protein transport
1.30 3.51e-07 GO:0016310 phosphorylation
1.40 3.72e-07 GO:0043066 negative regulation of apoptosis
1.51 4.09e-07 GO:0007264 small GTPase mediated signal transduction
1.41 4.24e-07 GO:0048598 embryonic morphogenesis
1.31 5.01e-07 GO:0031399 regulation of protein modification process
1.38 7.77e-07 GO:0060548 negative regulation of cell death
1.38 7.81e-07 GO:0043068 positive regulation of programmed cell death
1.50 9.56e-07 GO:0045664 regulation of neuron differentiation
1.47 9.67e-07 GO:0051098 regulation of binding
1.45 1.06e-06 GO:0051130 positive regulation of cellular component organization
1.37 1.32e-06 GO:0010942 positive regulation of cell death
1.46 1.60e-06 GO:0032535 regulation of cellular component size
1.54 1.66e-06 GO:0043193 positive regulation of gene-specific transcription
1.36 1.79e-06 GO:0008284 positive regulation of cell proliferation
1.38 1.97e-06 GO:0043069 negative regulation of programmed cell death
1.34 2.50e-06 GO:0071844 cellular component assembly at cellular level
1.37 2.93e-06 GO:0043065 positive regulation of apoptosis
1.38 3.57e-06 GO:0007010 cytoskeleton organization
1.41 3.98e-06 GO:0090066 regulation of anatomical structure size
1.51 3.99e-06 GO:0051101 regulation of DNA binding
1.46 4.19e-06 GO:0009259 ribonucleotide metabolic process
1.44 4.78e-06 GO:0009894 regulation of catabolic process
1.58 4.83e-06 GO:0016569 covalent chromatin modification
1.52 5.03e-06 GO:0030029 actin filament-based process
1.32 5.42e-06 GO:0043085 positive regulation of catalytic activity
1.36 6.00e-06 GO:0044282 small molecule catabolic process
1.60 6.02e-06 GO:0060562 epithelial tube morphogenesis
1.53 6.57e-06 GO:0001558 regulation of cell growth
1.53 6.86e-06 GO:0030036 actin cytoskeleton organization
1.54 7.15e-06 GO:0030900 forebrain development
1.18 7.60e-06 GO:0042221 response to chemical stimulus
1.46 7.80e-06 GO:0009150 purine ribonucleotide metabolic process
1.38 7.94e-06 GO:0051247 positive regulation of protein metabolic process
1.58 7.96e-06 GO:0016570 histone modification
1.29 8.57e-06 GO:0051049 regulation of transport
1.58 8.73e-06 GO:0007346 regulation of mitotic cell cycle
1.42 1.31e-05 GO:0007420 brain development
1.42 1.39e-05 GO:0051301 cell division
1.58 1.40e-05 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.38 1.44e-05 GO:0032270 positive regulation of cellular protein metabolic process
1.46 1.45e-05 GO:0009141 nucleoside triphosphate metabolic process
1.49 1.75e-05 GO:0010608 posttranscriptional regulation of gene expression
1.47 2.04e-05 GO:0009199 ribonucleoside triphosphate metabolic process
1.69 2.11e-05 GO:0003007 heart morphogenesis
1.52 2.53e-05 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity
1.38 2.62e-05 GO:0072521 purine-containing compound metabolic process
1.50 2.91e-05 GO:0009143 nucleoside triphosphate catabolic process
1.49 3.09e-05 GO:0048514 blood vessel morphogenesis
1.31 3.17e-05 GO:0022402 cell cycle process
1.51 3.37e-05 GO:0090046 regulation of transcription regulator activity
1.69 3.57e-05 GO:0035107 appendage morphogenesis
1.69 3.57e-05 GO:0035108 limb morphogenesis
1.68 3.62e-05 GO:0048736 appendage development
1.68 3.62e-05 GO:0060173 limb development
1.45 3.76e-05 GO:0009144 purine nucleoside triphosphate metabolic process
1.31 3.88e-05 GO:0001932 regulation of protein phosphorylation
1.58 4.17e-05 GO:0016055 Wnt receptor signaling pathway
1.50 4.42e-05 GO:0035239 tube morphogenesis
1.46 4.47e-05 GO:0009205 purine ribonucleoside triphosphate metabolic process
1.85 4.83e-05 GO:0009953 dorsal/ventral pattern formation
1.73 5.49e-05 GO:0016331 morphogenesis of embryonic epithelium
1.34 7.17e-05 GO:0005975 carbohydrate metabolic process
1.47 7.47e-05 GO:0032269 negative regulation of cellular protein metabolic process
1.47 7.47e-05 GO:0072523 purine-containing compound catabolic process
1.59 7.75e-05 GO:0045786 negative regulation of cell cycle
1.45 7.85e-05 GO:0051248 negative regulation of protein metabolic process
1.47 7.90e-05 GO:0008361 regulation of cell size
1.47 8.83e-05 GO:0006195 purine nucleotide catabolic process
1.39 9.10e-05 GO:0006163 purine nucleotide metabolic process
1.61 9.17e-05 GO:0060541 respiratory system development
1.36 9.59e-05 GO:0061024 membrane organization
1.49 1.01e-04 GO:0051129 negative regulation of cellular component organization
1.65 1.02e-04 GO:0030111 regulation of Wnt receptor signaling pathway
1.49 1.07e-04 GO:0009146 purine nucleoside triphosphate catabolic process
1.49 1.12e-04 GO:0009203 ribonucleoside triphosphate catabolic process
1.44 1.26e-04 GO:0031329 regulation of cellular catabolic process
1.51 1.28e-04 GO:0031344 regulation of cell projection organization
1.51 1.28e-04 GO:0032582 negative regulation of gene-specific transcription
1.25 1.42e-04 GO:0006629 lipid metabolic process
1.33 1.44e-04 GO:0006259 DNA metabolic process
1.41 1.50e-04 GO:0045596 negative regulation of cell differentiation
1.27 1.60e-04 GO:0006468 protein phosphorylation
1.71 1.66e-04 GO:0030326 embryonic limb morphogenesis
1.71 1.66e-04 GO:0035113 embryonic appendage morphogenesis
1.48 1.70e-04 GO:0009207 purine ribonucleoside triphosphate catabolic process
1.35 1.81e-04 GO:0016044 cellular membrane organization
1.44 1.84e-04 GO:0009166 nucleotide catabolic process
1.80 1.93e-04 GO:0030178 negative regulation of Wnt receptor signaling pathway
1.38 2.05e-04 GO:0008285 negative regulation of cell proliferation
1.41 2.28e-04 GO:0000904 cell morphogenesis involved in differentiation
1.60 2.37e-04 GO:0051169 nuclear transport
1.33 2.48e-04 GO:0032989 cellular component morphogenesis
1.36 2.65e-04 GO:0051093 negative regulation of developmental process
1.25 2.71e-04 GO:0048584 positive regulation of response to stimulus
1.40 3.25e-04 GO:0044270 cellular nitrogen compound catabolic process
1.33 3.28e-04 GO:0044283 small molecule biosynthetic process
1.32 3.57e-04 GO:0071310 cellular response to organic substance
1.34 3.88e-04 GO:0000902 cell morphogenesis
1.59 3.93e-04 GO:0006913 nucleocytoplasmic transport
1.46 4.06e-04 GO:0009261 ribonucleotide catabolic process
1.34 4.12e-04 GO:0009719 response to endogenous stimulus
1.42 4.37e-04 GO:0001501 skeletal system development
1.62 4.52e-04 GO:0030323 respiratory tube development
1.46 4.55e-04 GO:0009154 purine ribonucleotide catabolic process
1.40 4.76e-04 GO:0033043 regulation of organelle organization
1.36 4.78e-04 GO:0007389 pattern specification process
1.56 4.85e-04 GO:0048705 skeletal system morphogenesis
1.40 5.24e-04 GO:0046700 heterocycle catabolic process
1.33 5.42e-04 GO:0007417 central nervous system development
1.36 5.46e-04 GO:0044262 cellular carbohydrate metabolic process
1.53 5.49e-04 GO:0010975 regulation of neuron projection development
1.41 5.77e-04 GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
1.41 5.77e-04 GO:0034656 nucleobase, nucleoside and nucleotide catabolic process
1.36 5.90e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.41 6.55e-04 GO:0018193 peptidyl-amino acid modification
1.74 7.49e-04 GO:0010563 negative regulation of phosphorus metabolic process
1.74 7.49e-04 GO:0045936 negative regulation of phosphate metabolic process
1.33 7.60e-04 GO:0022403 cell cycle phase
1.30 8.19e-04 GO:0023056 positive regulation of signaling
1.37 8.22e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.50 8.43e-04 GO:0009100 glycoprotein metabolic process
1.27 8.94e-04 GO:0043933 macromolecular complex subunit organization
1.27 9.44e-04 GO:0042180 cellular ketone metabolic process
1.28 9.95e-04 GO:0040011 locomotion
1.27 1.03e-03 GO:0019752 carboxylic acid metabolic process
1.27 1.03e-03 GO:0043436 oxoacid metabolic process
1.26 1.05e-03 GO:0070887 cellular response to chemical stimulus
1.29 1.15e-03 GO:0010647 positive regulation of cell communication
1.60 1.20e-03 GO:0030324 lung development
1.62 1.31e-03 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.69 1.41e-03 GO:0034504 protein localization to nucleus
1.35 1.42e-03 GO:0009725 response to hormone stimulus
1.66 1.43e-03 GO:0031346 positive regulation of cell projection organization
1.52 1.44e-03 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
1.34 1.44e-03 GO:0000278 mitotic cell cycle
1.33 1.45e-03 GO:0006974 response to DNA damage stimulus
1.36 1.49e-03 GO:0031401 positive regulation of protein modification process
1.26 1.56e-03 GO:0006082 organic acid metabolic process
1.16 1.59e-03 GO:0006950 response to stress
1.37 1.60e-03 GO:0008283 cell proliferation
1.57 1.62e-03 GO:0010720 positive regulation of cell development
1.25 1.67e-03 GO:0022414 reproductive process
1.25 1.86e-03 GO:0000003 reproduction
1.34 1.89e-03 GO:0016477 cell migration
1.31 2.06e-03 GO:0006928 cellular component movement
1.30 2.07e-03 GO:0030030 cell projection organization
1.63 2.28e-03 GO:0021915 neural tube development
1.39 2.33e-03 GO:0048568 embryonic organ development
1.30 2.37e-03 GO:0051336 regulation of hydrolase activity
1.66 2.41e-03 GO:0018205 peptidyl-lysine modification
1.45 2.56e-03 GO:0046578 regulation of Ras protein signal transduction
1.27 2.80e-03 GO:0065003 macromolecular complex assembly
1.53 2.91e-03 GO:0042692 muscle cell differentiation
1.30 3.12e-03 GO:0009967 positive regulation of signal transduction
1.29 3.13e-03 GO:0009057 macromolecule catabolic process
1.44 3.32e-03 GO:0010564 regulation of cell cycle process
1.22 3.44e-03 GO:0042592 homeostatic process
1.62 3.74e-03 GO:0042176 regulation of protein catabolic process
1.71 3.92e-03 GO:0042326 negative regulation of phosphorylation
1.31 4.04e-03 GO:0048666 neuron development
1.41 4.20e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.56 4.38e-03 GO:0046039 GTP metabolic process
1.34 4.53e-03 GO:0007423 sensory organ development
1.46 4.60e-03 GO:0033365 protein localization to organelle
1.52 4.72e-03 GO:0051099 positive regulation of binding
1.50 4.91e-03 GO:0060537 muscle tissue development
1.41 5.07e-03 GO:0032880 regulation of protein localization
1.58 5.19e-03 GO:0006184 GTP catabolic process
1.19 5.87e-03 GO:0010033 response to organic substance
1.42 6.20e-03 GO:0048732 gland development
1.48 6.36e-03 GO:0006605 protein targeting
1.62 6.51e-03 GO:0017038 protein import
1.51 6.62e-03 GO:0014706 striated muscle tissue development
1.63 6.72e-03 GO:0007265 Ras protein signal transduction
1.52 7.63e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.52 7.63e-03 GO:0022604 regulation of cell morphogenesis
1.57 8.30e-03 GO:0045792 negative regulation of cell size
1.53 8.75e-03 GO:0006417 regulation of translation
1.41 9.36e-03 GO:0051345 positive regulation of hydrolase activity
1.59 9.42e-03 GO:0050769 positive regulation of neurogenesis
1.33 1.13e-02 GO:0007243 intracellular protein kinase cascade
1.33 1.13e-02 GO:0023014 signal transduction via phosphorylation event
1.70 1.16e-02 GO:0006473 protein acetylation
1.34 1.29e-02 GO:0003006 developmental process involved in reproduction
1.31 1.45e-02 GO:0006066 alcohol metabolic process
1.05 1.49e-02 GO:0065007 biological regulation
1.25 1.58e-02 GO:0044255 cellular lipid metabolic process
1.50 1.62e-02 GO:0009101 glycoprotein biosynthetic process
1.26 1.63e-02 GO:0030182 neuron differentiation
2.01 1.69e-02 GO:0048146 positive regulation of fibroblast proliferation
1.48 1.69e-02 GO:0048545 response to steroid hormone stimulus
1.77 1.69e-02 GO:0009798 axis specification
1.29 1.77e-02 GO:0051338 regulation of transferase activity
1.88 1.87e-02 GO:0060349 bone morphogenesis
1.73 1.88e-02 GO:0016573 histone acetylation
1.73 1.88e-02 GO:0034330 cell junction organization
1.72 1.92e-02 GO:0006475 internal protein amino acid acetylation
1.72 1.92e-02 GO:0018393 internal peptidyl-lysine acetylation
1.63 1.93e-02 GO:0045787 positive regulation of cell cycle
1.33 1.94e-02 GO:0031175 neuron projection development
1.71 1.95e-02 GO:0048738 cardiac muscle tissue development
1.26 1.98e-02 GO:0044092 negative regulation of molecular function
1.48 1.99e-02 GO:0006260 DNA replication
1.29 2.03e-02 GO:0048870 cell motility
1.29 2.03e-02 GO:0051674 localization of cell
1.37 2.12e-02 GO:0003002 regionalization
1.35 2.18e-02 GO:0012502 induction of programmed cell death
1.28 2.18e-02 GO:0070271 protein complex biogenesis
1.84 2.27e-02 GO:0048145 regulation of fibroblast proliferation
1.28 2.33e-02 GO:0006461 protein complex assembly
1.29 2.33e-02 GO:0044265 cellular macromolecule catabolic process
1.56 2.33e-02 GO:0030308 negative regulation of cell growth
1.94 2.44e-02 GO:0042733 embryonic digit morphogenesis
1.28 2.63e-02 GO:0071822 protein complex subunit organization
1.53 2.75e-02 GO:0010638 positive regulation of organelle organization
1.77 2.91e-02 GO:0014020 primary neural tube formation
1.35 2.98e-02 GO:0006917 induction of apoptosis
1.47 2.99e-02 GO:0001655 urogenital system development
1.63 3.25e-02 GO:0035148 tube formation
1.72 3.29e-02 GO:0009411 response to UV
1.31 3.32e-02 GO:0008610 lipid biosynthetic process
1.71 3.34e-02 GO:0006606 protein import into nucleus
1.70 3.38e-02 GO:0018394 peptidyl-lysine acetylation
1.70 3.38e-02 GO:0051170 nuclear import
1.05 3.41e-02 GO:0050789 regulation of biological process
1.55 3.70e-02 GO:0021537 telencephalon development
1.36 3.83e-02 GO:0048812 neuron projection morphogenesis
1.96 4.09e-02 GO:0045216 cell-cell junction organization
1.46 4.22e-02 GO:0045926 negative regulation of growth

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.26 4.82e-200 GO:0005622 intracellular
1.27 1.59e-193 GO:0044424 intracellular part
1.27 3.01e-144 GO:0043226 organelle
1.27 3.72e-143 GO:0043229 intracellular organelle
1.28 3.20e-130 GO:0043227 membrane-bounded organelle
1.28 3.30e-129 GO:0005737 cytoplasm
1.28 1.98e-128 GO:0043231 intracellular membrane-bounded organelle
1.31 1.32e-76 GO:0005634 nucleus
1.28 3.05e-73 GO:0044444 cytoplasmic part
1.10 2.67e-66 GO:0005623 cell
1.10 2.67e-66 GO:0044464 cell part
1.29 2.61e-49 GO:0044446 intracellular organelle part
1.28 1.11e-48 GO:0044422 organelle part
1.30 3.26e-35 GO:0043234 protein complex
1.27 2.66e-34 GO:0032991 macromolecular complex
1.38 5.91e-33 GO:0044428 nuclear part
1.38 1.97e-30 GO:0043233 organelle lumen
1.38 3.02e-30 GO:0070013 intracellular organelle lumen
1.40 3.04e-30 GO:0005829 cytosol
1.37 9.52e-30 GO:0031974 membrane-enclosed lumen
1.39 2.12e-27 GO:0031981 nuclear lumen
1.42 1.76e-21 GO:0005654 nucleoplasm
1.25 3.46e-20 GO:0043228 non-membrane-bounded organelle
1.25 3.46e-20 GO:0043232 intracellular non-membrane-bounded organelle
1.41 2.68e-19 GO:0005794 Golgi apparatus
1.45 5.07e-16 GO:0044451 nucleoplasm part
1.30 1.93e-12 GO:0000267 cell fraction
1.25 1.00e-11 GO:0005739 mitochondrion
1.35 1.15e-11 GO:0012505 endomembrane system
1.25 9.49e-11 GO:0005856 cytoskeleton
1.47 4.77e-09 GO:0005625 soluble fraction
1.24 4.10e-08 GO:0031090 organelle membrane
1.40 5.74e-08 GO:0005768 endosome
1.82 1.04e-07 GO:0019898 extrinsic to membrane
1.25 1.56e-07 GO:0042995 cell projection
1.25 3.10e-07 GO:0005783 endoplasmic reticulum
1.26 4.58e-07 GO:0005626 insoluble fraction
1.47 5.23e-07 GO:0044431 Golgi apparatus part
1.29 7.43e-07 GO:0031982 vesicle
1.27 1.27e-05 GO:0031410 cytoplasmic vesicle
1.31 1.29e-05 GO:0015630 microtubule cytoskeleton
1.41 2.09e-05 GO:0005667 transcription factor complex
2.16 3.07e-05 GO:0000118 histone deacetylase complex
1.41 3.61e-05 GO:0048471 perinuclear region of cytoplasm
1.52 3.96e-05 GO:0044454 nuclear chromosome part
1.23 4.47e-05 GO:0005624 membrane fraction
1.33 5.19e-05 GO:0005694 chromosome
1.34 5.59e-05 GO:0044427 chromosomal part
1.28 6.17e-05 GO:0031967 organelle envelope
1.52 7.01e-05 GO:0031252 cell leading edge
1.82 7.34e-05 GO:0019897 extrinsic to plasma membrane
1.27 8.96e-05 GO:0031975 envelope
1.77 9.32e-05 GO:0016585 chromatin remodeling complex
1.29 9.42e-05 GO:0031988 membrane-bounded vesicle
1.87 9.60e-05 GO:0000123 histone acetyltransferase complex
1.47 9.91e-05 GO:0000228 nuclear chromosome
1.60 1.01e-04 GO:0005912 adherens junction
2.02 1.04e-04 GO:0017053 transcriptional repressor complex
1.70 1.16e-04 GO:0000790 nuclear chromatin
1.54 1.54e-04 GO:0000139 Golgi membrane
1.47 5.43e-04 GO:0005635 nuclear envelope
1.21 6.32e-04 GO:0044430 cytoskeletal part
1.62 9.08e-04 GO:0005769 early endosome
1.52 1.17e-03 GO:0070161 anchoring junction
1.24 1.29e-03 GO:0030054 cell junction
2.09 1.41e-03 GO:0005793 ER-Golgi intermediate compartment
1.27 1.49e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.14 1.76e-03 GO:0044459 plasma membrane part
1.80 2.13e-03 GO:0034708 methyltransferase complex
1.80 2.13e-03 GO:0035097 histone methyltransferase complex
2.65 2.52e-03 GO:0016581 NuRD complex
1.65 2.76e-03 GO:0009898 internal side of plasma membrane
1.35 3.25e-03 GO:0015629 actin cytoskeleton
2.37 3.59e-03 GO:0031519 PcG protein complex
1.24 4.10e-03 GO:0043005 neuron projection
1.09 5.99e-03 GO:0071944 cell periphery
1.35 7.62e-03 GO:0005874 microtubule
1.29 8.83e-03 GO:0005730 nucleolus
1.37 1.36e-02 GO:0016323 basolateral plasma membrane
1.35 1.43e-02 GO:0000323 lytic vacuole
1.35 1.43e-02 GO:0005764 lysosome
1.49 2.03e-02 GO:0031301 integral to organelle membrane
1.08 2.27e-02 GO:0005886 plasma membrane
2.46 2.29e-02 GO:0000932 cytoplasmic mRNA processing body
1.36 2.64e-02 GO:0000785 chromatin
1.44 3.33e-02 GO:0031300 intrinsic to organelle membrane
1.79 3.42e-02 GO:0005913 cell-cell adherens junction
1.79 3.42e-02 GO:0042641 actomyosin
1.28 3.58e-02 GO:0044297 cell body
1.90 4.28e-02 GO:0005834 heterotrimeric G-protein complex
1.56 4.96e-02 GO:0005802 trans-Golgi network

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.21 5.40e-116 GO:0005488 binding
1.29 5.24e-81 GO:0005515 protein binding
1.19 9.78e-31 GO:0003824 catalytic activity
1.28 4.48e-27 GO:0003676 nucleic acid binding
1.27 1.48e-20 GO:0000166 nucleotide binding
1.21 3.88e-20 GO:0046872 metal ion binding
1.21 4.51e-20 GO:0043167 ion binding
1.21 4.70e-20 GO:0043169 cation binding
1.30 1.57e-19 GO:0003677 DNA binding
1.43 2.14e-18 GO:0019899 enzyme binding
1.29 1.42e-17 GO:0016740 transferase activity
1.40 2.60e-17 GO:0030528 transcription regulator activity
1.26 3.50e-15 GO:0035639 purine ribonucleoside triphosphate binding
1.26 4.88e-15 GO:0032553 ribonucleotide binding
1.26 6.17e-15 GO:0017076 purine nucleotide binding
1.26 6.32e-15 GO:0032555 purine ribonucleotide binding
1.27 9.90e-15 GO:0046914 transition metal ion binding
1.43 2.91e-14 GO:0043565 sequence-specific DNA binding
1.48 3.78e-14 GO:0019904 protein domain specific binding
1.39 1.04e-13 GO:0042802 identical protein binding
1.29 1.65e-13 GO:0008270 zinc ion binding
1.58 6.18e-12 GO:0008134 transcription factor binding
1.26 1.28e-11 GO:0030554 adenyl nucleotide binding
1.26 1.31e-11 GO:0032559 adenyl ribonucleotide binding
1.26 2.49e-11 GO:0005524 ATP binding
1.54 3.85e-11 GO:0016563 transcription activator activity
1.31 1.19e-10 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.35 1.20e-10 GO:0001071 nucleic acid binding transcription factor activity
1.35 1.20e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
1.53 4.57e-10 GO:0016564 transcription repressor activity
1.64 6.35e-09 GO:0010843 promoter binding
1.62 9.51e-09 GO:0000975 regulatory region DNA binding
1.62 9.51e-09 GO:0001067 regulatory region nucleic acid binding
1.62 9.51e-09 GO:0044212 transcription regulatory region DNA binding
1.38 3.09e-08 GO:0008092 cytoskeletal protein binding
1.30 9.64e-08 GO:0016301 kinase activity
1.31 1.76e-07 GO:0046983 protein dimerization activity
1.27 9.23e-07 GO:0030234 enzyme regulator activity
1.40 1.47e-06 GO:0030695 GTPase regulator activity
1.54 3.93e-06 GO:0003682 chromatin binding
1.50 4.10e-06 GO:0000989 transcription factor binding transcription factor activity
1.29 5.28e-06 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.50 6.22e-06 GO:0003712 transcription cofactor activity
1.38 6.34e-06 GO:0060589 nucleoside-triphosphatase regulator activity
1.48 1.21e-05 GO:0000988 protein binding transcription factor activity
1.34 1.78e-05 GO:0042803 protein homodimerization activity
1.41 3.63e-05 GO:0008047 enzyme activator activity
1.45 5.56e-05 GO:0019901 protein kinase binding
1.41 6.67e-05 GO:0019900 kinase binding
1.27 1.82e-04 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.26 2.19e-04 GO:0016817 hydrolase activity, acting on acid anhydrides
1.26 2.50e-04 GO:0016462 pyrophosphatase activity
1.25 2.61e-04 GO:0003723 RNA binding
1.27 2.80e-04 GO:0017111 nucleoside-triphosphatase activity
1.41 5.87e-04 GO:0005083 small GTPase regulator activity
1.13 6.28e-04 GO:0016787 hydrolase activity
1.34 7.26e-04 GO:0032403 protein complex binding
1.59 1.56e-03 GO:0017124 SH3 domain binding
1.65 1.90e-03 GO:0003714 transcription corepressor activity
1.39 2.25e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.43 2.47e-03 GO:0005096 GTPase activator activity
1.43 4.30e-03 GO:0043566 structure-specific DNA binding
1.54 5.07e-03 GO:0051020 GTPase binding
1.25 6.53e-03 GO:0004672 protein kinase activity
1.39 7.39e-03 GO:0016881 acid-amino acid ligase activity
1.29 1.02e-02 GO:0016874 ligase activity
1.49 1.14e-02 GO:0003690 double-stranded DNA binding
1.33 1.32e-02 GO:0003779 actin binding
1.71 1.55e-02 GO:0016407 acetyltransferase activity
1.54 1.60e-02 GO:0031267 small GTPase binding
1.43 2.43e-02 GO:0008022 protein C-terminus binding
1.61 2.47e-02 GO:0005099 Ras GTPase activator activity
1.29 3.60e-02 GO:0005525 GTP binding
1.44 3.73e-02 GO:0000287 magnesium ion binding
1.26 3.93e-02 GO:0004674 protein serine/threonine kinase activity
1.61 4.13e-02 GO:0008017 microtubule binding
1.75 4.24e-02 GO:0046332 SMAD binding