• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: SPI1.p2

Z-value: 4.314

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_+_78075220	100.253	NM_008677	Ncf4	neutrophil cytosolic factor 4
chr17_+_34726750	76.746	NM_134116	Gpsm3	G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr17_+_34727032	69.542		Gpsm3	G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr11_-_16908631	63.096	NM_019549	Plek	pleckstrin
chr15_-_102062309	59.277		Itgb7	integrin beta 7
chr11_-_69479553	54.821	NM_009853	Cd68	CD68 antigen
chr3_-_106592919	53.996	NM_007651	Cd53	CD53 antigen
chr19_-_6932673	53.462	NM_001081291	Ccdc88b	coiled-coil domain containing 88B
chr15_+_103284200	53.001	NM_153505	Nckap1l	NCK associated protein 1 like
chrX_-_20508314	52.823		Cfp	complement factor properdin
chr1_-_173164404	52.173	NM_010185	Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide
chr7_-_52494453	51.119		Cd37	CD37 antigen
chr6_+_145070255	50.793	NM_008511	Lrmp	lymphoid-restricted membrane protein
chrX_-_7667574	50.291	NM_009515	Was	Wiskott-Aldrich syndrome homolog (human)
chr9_-_57492978	48.465	NM_007783	Csk	c-src tyrosine kinase
chrX_-_98463514	48.264	NM_013563	Il2rg	interleukin 2 receptor, gamma chain
chr7_+_133728483	46.882	NM_138310	Apobr	apolipoprotein B receptor
chr15_-_102062331	46.853	NM_013566	Itgb7	integrin beta 7
chr11_-_79337178	46.154		Evi2b	ecotropic viral integration site 2b
chr2_+_92024338	44.800	NM_138755	Phf21a	PHD finger protein 21A
chr11_+_95703598	44.411	NM_023121	Gngt2	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr18_+_65590615	43.773	NM_172833	Malt1	mucosa associated lymphoid tissue lymphoma translocation gene 1
chr17_+_36003527	43.696	NM_175242	2310014H01Rik	RIKEN cDNA 2310014H01 gene
chr19_+_10917432	42.635		Slc15a3	solute carrier family 15, member 3
chr7_-_3820753	41.588		Gm10693	predicted pseudogene 10693
chr9_-_57493393	40.426		Csk	c-src tyrosine kinase
chr19_+_10917005	40.283	NM_023044	Slc15a3	solute carrier family 15, member 3
chr4_+_130469187	40.161	NM_010686	Laptm5	lysosomal-associated protein transmembrane 5
chr9_-_32348863	39.822	NM_008026	Fli1	Friend leukemia integration 1
chr2_-_25052129	38.837		A830007P12Rik	RIKEN cDNA A830007P12 gene
chr4_+_130469048	38.548		Laptm5	lysosomal-associated protein transmembrane 5
chr11_-_34597324	37.069	NM_033374	Dock2	dedicator of cyto-kinesis 2
chr14_-_33998251	37.059	NM_001146022	Wdfy4	WD repeat and FYVE domain containing 4
chr8_-_124956759	35.712	NM_007806	Cyba	cytochrome b-245, alpha polypeptide
chr7_-_3867085	35.638	NM_011087 NM_011090	Pira1 Lilra6	paired-Ig-like receptor A1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr16_+_52031704	35.546		Cblb	Casitas B-lineage lymphoma b
chr19_-_5661634	34.912		Sipa1	signal-induced proliferation associated gene 1
chr7_+_133728451	34.775		Apobr	apolipoprotein B receptor
chrX_-_71527052	34.694	NM_027109	Dnase1l1	deoxyribonuclease 1-like 1
chr11_-_83462722	34.508	NM_011337	Ccl3	chemokine (C-C motif) ligand 3
chr8_+_90818102	34.301	NM_001037724	Adcy7	adenylate cyclase 7
chr19_+_10917326	34.292		Slc15a3	solute carrier family 15, member 3
chr11_+_68245608	34.191	NM_177320	Pik3r5	phosphoinositide-3-kinase, regulatory subunit 5, p101
chr13_-_117814079	34.094		Parp8	poly (ADP-ribose) polymerase family, member 8
chr7_-_29164215	34.039	NM_011756	Zfp36	zinc finger protein 36
chr16_-_75909440	34.016	NM_023380	Samsn1	SAM domain, SH3 domain and nuclear localization signals, 1
chr7_-_52494097	33.940	NM_007645	Cd37	CD37 antigen
chr19_+_12873115	33.824		Lpxn	leupaxin
chr11_+_33946927	33.223		Lcp2	lymphocyte cytosolic protein 2
chr7_-_3671918	33.106	NM_011095	Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
chr19_+_12873063	32.240	NM_134152	Lpxn	leupaxin
chrX_+_155693729	32.122		Rps6ka3	ribosomal protein S6 kinase polypeptide 3
chr13_-_55122654	32.046		Hk3	hexokinase 3
chr1_-_133173495	31.979		Ikbke	inhibitor of kappaB kinase epsilon
chrX_-_71526939	31.880		Dnase1l1	deoxyribonuclease 1-like 1
chr3_+_90472990	31.658	NM_013650	S100a8	S100 calcium binding protein A8 (calgranulin A)
chr11_+_60955985	31.311		Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b
chr13_+_52678541	31.127		Sykb	spleen tyrosine kinase
chr7_-_109398578	30.923	NM_019566	Rhog	ras homolog gene family, member G
chr11_+_62389367	30.822		Trpv2	transient receptor potential cation channel, subfamily V, member 2
chr9_+_55937776	30.684	NM_011193	Pstpip1	proline-serine-threonine phosphatase-interacting protein 1
chr11_-_79337251	30.626	NM_001077496	Evi2b	ecotropic viral integration site 2b
chr1_+_154654953	30.624	NM_010877	Ncf2	neutrophil cytosolic factor 2
chr1_+_173319048	30.529	NM_001005508	Arhgap30	Rho GTPase activating protein 30
chr11_-_114995194	30.443	NM_001169153 NM_145634	Cd300lf	CD300 antigen like family member F
chr4_+_3605207	30.179	NM_001111096 NM_010747	Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
chr7_+_4225744	30.172	NM_011093 NM_008848	Pira6	paired-Ig-like receptor A6
chr10_+_40069255	29.507		Cdk19	cyclin-dependent kinase 19
chr9_+_108941083	29.297	NM_025858	Shisa5	shisa homolog 5 (Xenopus laevis)
chr4_-_133684552	29.089		Sh3bgrl3	SH3 domain binding glutamic acid-rich protein-like 3
chr11_+_83476085	28.921	NM_013652	Ccl4	chemokine (C-C motif) ligand 4
chr11_-_114862859	28.790		AF251705	cDNA sequence AF251705
chr12_-_32893074	28.779	NM_001146201 NM_020272 NM_001146200	Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr19_-_41459518	28.730	NM_031376	Pik3ap1	phosphoinositide-3-kinase adaptor protein 1
chr5_+_150076605	28.726	NM_009663	Alox5ap	arachidonate 5-lipoxygenase activating protein
chr4_-_43467398	28.710	NM_001110320 NM_001110321 NM_001110322 NM_007654	Cd72	CD72 antigen
chr10_-_117282901	28.305		Rap1b	RAS related protein 1b
chr9_+_55937980	28.244		Pstpip1	proline-serine-threonine phosphatase-interacting protein 1
chr8_+_87225355	28.243	NM_008535	Lyl1	lymphoblastomic leukemia 1
chr17_+_33692639	27.884	NM_053214	Myo1f	myosin IF
chr7_+_31208322	27.748	NM_172142	Nfkbid	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr19_-_18706239	27.613	NM_017375	Ostf1	osteoclast stimulating factor 1
chr7_+_134628622	27.344	NM_010183	Fbrs	fibrosin
chr17_+_48439264	27.306	NM_001033405	Treml2	triggering receptor expressed on myeloid cells-like 2
chr5_+_145875080	26.957	NM_023142	Arpc1b	actin related protein 2/3 complex, subunit 1B
chr2_+_79095582	26.898	NM_010576	Itga4	integrin alpha 4
chr17_+_35187325	26.876		Clic1	chloride intracellular channel 1
chr11_+_4136787	26.840	NM_001013365	Osm	oncostatin M
chr6_-_124683046	26.633	NM_013545	Ptpn6	protein tyrosine phosphatase, non-receptor type 6
chr1_+_34529567	26.484		Ptpn18	protein tyrosine phosphatase, non-receptor type 18
chr15_-_77599271	26.129		Myh9	myosin, heavy polypeptide 9, non-muscle
chr4_-_123427465	25.961	NM_023423	Akirin1	akirin 1
chr1_-_97564139	25.801	NM_001159745 NM_009183	St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr19_-_18706181	25.744		Ostf1	osteoclast stimulating factor 1
chr18_-_36886307	25.524	NM_009841	Cd14	CD14 antigen
chr17_+_36005333	25.301		2310014H01Rik	RIKEN cDNA 2310014H01 gene
chr2_+_43604343	24.570	NM_153820 NM_001025377	Arhgap15	Rho GTPase activating protein 15
chr11_+_3190334	24.418	NM_019574	Patz1	POZ (BTB) and AT hook containing zinc finger 1
chr8_+_90812964	24.402	NM_001037723	Adcy7	adenylate cyclase 7
chr11_-_109334909	24.309	NM_001029842	Slc16a6	solute carrier family 16 (monocarboxylic acid transporters), member 6
chr17_+_36003000	24.279	NM_001146710	2310014H01Rik	RIKEN cDNA 2310014H01 gene
chr11_+_33947115	23.996	NM_010696	Lcp2	lymphocyte cytosolic protein 2
chr18_-_36886375	23.820		Cd14	CD14 antigen
chr10_+_127080013	23.735	NM_009284	Stat6	signal transducer and activator of transcription 6
chr14_-_103381744	23.418	NM_177715	Kctd12	potassium channel tetramerisation domain containing 12
chr13_-_117814322	23.226	NM_001081009	Parp8	poly (ADP-ribose) polymerase family, member 8
chr10_+_57834201	23.158	NM_201242	Lims1	LIM and senescent cell antigen-like domains 1
chr3_+_87180308	23.061	NM_001136236 NM_153090 NM_178165	Fcrl1	Fc receptor-like 1
chr13_+_52678805	22.994	NM_001198977	Sykb	spleen tyrosine kinase
chr18_-_36886051	22.957		Cd14	CD14 antigen
chr1_+_173612173	22.905	NM_007649	Cd48	CD48 antigen
chr12_-_56087322	22.765	NM_013815	Baz1a	bromodomain adjacent to zinc finger domain 1A
chrX_+_33428784	22.653	NM_001009947	Dock11	dedicator of cytokinesis 11
chr12_+_113998865	22.557	NM_178911	Pld4	phospholipase D family, member 4
chr17_+_88840048	22.296	NM_180974	Foxn2	forkhead box N2
chr10_+_41196119	22.202	NM_001164433 NM_138315	Mical1	microtubule associated monoxygenase, calponin and LIM domain containing 1
chr17_+_35331446	22.140	NM_008518	Ltb	lymphotoxin B
chr19_+_3935169	21.902	NM_001161428 NM_019449	Unc93b1	unc-93 homolog B1 (C. elegans)
chr17_+_35400983	21.592		H2-D1	histocompatibility 2, D region locus 1
chr6_-_123239886	21.421	NM_019948	Clec4e	C-type lectin domain family 4, member e
chr3_+_87161790	21.293	NM_009690	Cd5l	CD5 antigen-like
chr15_+_6529846	21.257	NM_011815	Fyb	FYN binding protein
chr8_-_125222837	21.074	NM_009824	Cbfa2t3	core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr5_-_122286849	21.062		Sh2b3	SH2B adaptor protein 3
chr2_-_113688771	20.998	NM_181416	Arhgap11a	Rho GTPase activating protein 11A
chr17_+_36002537	20.922	NM_001146711	2310014H01Rik	RIKEN cDNA 2310014H01 gene
chr10_-_60561786	20.670
chr2_-_34813633	20.532		Traf1	TNF receptor-associated factor 1
chr17_-_35325354	20.468	NM_010734	Lst1	leukocyte specific transcript 1
chr13_-_55122670	20.188	NM_001033245	Hk3	hexokinase 3
chr4_-_133684599	20.157	NM_080559	Sh3bgrl3	SH3 domain binding glutamic acid-rich protein-like 3
chr10_+_40069113	19.983	NM_001168304 NM_198164	Cdk19	cyclin-dependent kinase 19
chr19_-_11679293	19.950	NM_026835	Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D
chr16_+_52031661	19.946	NM_001033238	Cblb	Casitas B-lineage lymphoma b
chr17_+_34729159	19.902		Pbx2	pre B-cell leukemia transcription factor 2
chr1_-_146622545	19.883	NM_022881	Rgs18	regulator of G-protein signaling 18
chr19_-_11679242	19.783		Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D
chr10_+_96079634	19.781	NM_007569	Btg1	B-cell translocation gene 1, anti-proliferative
chr8_+_106864488	19.772	NM_024217	Cmtm3	CKLF-like MARVEL transmembrane domain containing 3
chr11_+_95703981	19.387	NM_001038664	Gngt2	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr19_-_41068625	19.331		Blnk	B-cell linker
chr1_-_97564064	19.210		St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr18_+_70727897	19.195	NM_010773	Mbd2	methyl-CpG binding domain protein 2
chr11_-_117830554	19.065	NM_007707	Socs3	suppressor of cytokine signaling 3
chrX_-_20508584	19.012	NM_008823	Cfp	complement factor properdin
chr15_+_84155149	18.985	NM_022321	Parvg	parvin, gamma
chr13_-_55122556	18.922		Hk3	hexokinase 3
chr17_-_35338849	18.777	NM_013693	Tnf	tumor necrosis factor
chr1_-_133096633	18.743		Rassf5	Ras association (RalGDS/AF-6) domain family member 5
chr10_+_79460226	18.725	NM_013850	Abca7	ATP-binding cassette, sub-family A (ABC1), member 7
chr7_-_108112785	18.670	NM_183168	P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6
chr7_-_53176218	18.636	NM_001146346	Emp3	epithelial membrane protein 3
chr2_-_25052245	18.554	NM_146115	A830007P12Rik	RIKEN cDNA A830007P12 gene
chr7_+_29767872	18.473	NM_008279	Map4k1	mitogen-activated protein kinase kinase kinase kinase 1
chr1_-_140071818	18.435	NM_001111316 NM_011210	Ptprc	protein tyrosine phosphatase, receptor type, C
chrX_+_103338609	18.401	NM_205820	Tlr13	toll-like receptor 13
chr13_-_37141055	18.381	NM_028784	F13a1	coagulation factor XIII, A1 subunit
chr14_+_103446193	18.218		Irg1	immunoresponsive gene 1
chr16_-_32165509	18.078	NM_146069	Lrrc33	leucine rich repeat containing 33
chr7_+_135273060	17.982	NM_021334	Itgax	integrin alpha X
chr10_-_60561763	17.966
chr10_-_117283020	17.946	NM_024457	Rap1b	RAS related protein 1b
chr9_+_7764067	17.906	NM_133739	Tmem123	transmembrane protein 123
chr1_-_99558490	17.856	NM_133825	D1Ertd622e	DNA segment, Chr 1, ERATO Doi 622, expressed
chr2_-_126317267	17.785	NM_001080944	Atp8b4	ATPase, class I, type 8B, member 4
chr8_+_108583449	17.760	NM_010901	Nfatc3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr1_+_133763777	17.753	NM_144875	Rab7l1	RAB7, member RAS oncogene family-like 1
chr5_-_141476549	17.722	NM_175362	Card11	caspase recruitment domain family, member 11
chr13_-_12742377	17.468		Gpr137b-ps Gpr137b	G protein-coupled receptor 137B, pseudogene G protein-coupled receptor 137B
chr1_-_99558252	17.383		D1Ertd622e	DNA segment, Chr 1, ERATO Doi 622, expressed
chr10_-_94407211	17.375	NM_018797	Plxnc1	plexin C1
chr19_+_4154645	17.356	NM_016933	Ptprcap	protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr13_+_83663817	17.346		Mef2c	myocyte enhancer factor 2C
chr17_+_35187185	17.279	NM_033444	Clic1	chloride intracellular channel 1
chr2_-_34813680	17.229		Traf1	TNF receptor-associated factor 1
chr3_-_90499611	17.156	NM_009114	S100a9	S100 calcium binding protein A9 (calgranulin B)
chr19_-_4190836	17.125	NM_178650	Tbc1d10c	TBC1 domain family, member 10c
chr3_+_89883564	17.093		Tpm3	tropomyosin 3, gamma
chr7_+_17491838	17.066	NM_008967	Ptgir	prostaglandin I receptor (IP)
chr19_-_3907120	17.007	NM_001136091	Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
chr17_+_34729396	16.980	NM_017463	Pbx2	pre B-cell leukemia transcription factor 2
chr13_-_51889012	16.957	NM_013660	Sema4d	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr2_+_131012677	16.730	NM_001111075 NM_023117	Cdc25b	cell division cycle 25 homolog B (S. pombe)
chr11_+_93857338	16.607	NM_027569	Spag9	sperm associated antigen 9
chr13_+_52678866	16.525		Sykb	spleen tyrosine kinase
chr1_+_173770709	16.495	NM_013489	Cd84	CD84 antigen
chr6_+_29479250	16.408		Irf5	interferon regulatory factor 5
chr2_+_167757867	16.405		Ptpn1	protein tyrosine phosphatase, non-receptor type 1
chr11_+_53583515	16.392	NM_001159393 NM_008390	Irf1	interferon regulatory factor 1
chr2_+_4480799	16.377	NM_001177844	Frmd4a	FERM domain containing 4A
chr1_-_64167818	16.329		Klf7	Kruppel-like factor 7 (ubiquitous)
chr14_+_75576599	16.307		Lcp1	lymphocyte cytosolic protein 1
chr8_-_40727989	16.194	NM_001113326 NM_031195	Msr1	macrophage scavenger receptor 1
chr12_+_33063653	16.137	NM_001162903	2010109K11Rik	RIKEN cDNA 2010109K11 gene
chr12_+_103521355	16.042		Rin3	Ras and Rab interactor 3
chr1_-_80661844	16.035		Dock10	dedicator of cytokinesis 10
chr11_-_115560691	15.969		Grb2	growth factor receptor bound protein 2
chr2_+_22629846	15.743	NM_019456	Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr10_+_129759907	15.719	NM_183264	5830405N20Rik	RIKEN cDNA 5830405N20 gene
chr10_+_122116066	15.708		Ppm1h	protein phosphatase 1H (PP2C domain containing)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.45	9.39e-64	GO:0044260	cellular macromolecule metabolic process
1.52	4.71e-60	GO:0031323	regulation of cellular metabolic process
1.40	3.02e-59	GO:0043170	macromolecule metabolic process
1.51	2.30e-57	GO:0080090	regulation of primary metabolic process
1.61	1.29e-55	GO:0010556	regulation of macromolecule biosynthetic process
1.59	1.34e-55	GO:0051171	regulation of nitrogen compound metabolic process
1.46	2.03e-55	GO:0019222	regulation of metabolic process
1.51	2.13e-55	GO:0060255	regulation of macromolecule metabolic process
1.59	1.03e-54	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59	1.90e-54	GO:0010468	regulation of gene expression
1.58	3.20e-54	GO:0009889	regulation of biosynthetic process
1.61	4.56e-54	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.58	7.27e-54	GO:0031326	regulation of cellular biosynthetic process
1.58	1.89e-53	GO:0090304	nucleic acid metabolic process
1.62	3.56e-51	GO:0051252	regulation of RNA metabolic process
1.62	7.25e-50	GO:0006355	regulation of transcription, DNA-dependent
1.61	2.45e-49	GO:0016070	RNA metabolic process
1.50	3.18e-49	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.57	9.49e-48	GO:0010467	gene expression
1.30	7.42e-45	GO:0044238	primary metabolic process
1.30	2.80e-43	GO:0044237	cellular metabolic process
1.65	1.28e-40	GO:0032774	RNA biosynthetic process
1.65	3.18e-40	GO:0006351	transcription, DNA-dependent
1.43	3.84e-40	GO:0034641	cellular nitrogen compound metabolic process
1.42	1.01e-39	GO:0006807	nitrogen compound metabolic process
1.52	4.27e-37	GO:0009059	macromolecule biosynthetic process
1.52	7.99e-37	GO:0034645	cellular macromolecule biosynthetic process
1.24	2.54e-34	GO:0008152	metabolic process
1.84	1.19e-32	GO:0002376	immune system process
1.44	1.33e-31	GO:0048518	positive regulation of biological process
1.45	4.21e-29	GO:0048522	positive regulation of cellular process
1.37	4.87e-25	GO:0044249	cellular biosynthetic process
1.43	1.13e-24	GO:0048519	negative regulation of biological process
1.36	3.34e-24	GO:0009058	biosynthetic process
1.44	3.51e-23	GO:0048523	negative regulation of cellular process
1.12	5.14e-22	GO:0009987	cellular process
1.55	3.22e-20	GO:0010604	positive regulation of macromolecule metabolic process
1.52	1.35e-19	GO:0009893	positive regulation of metabolic process
1.54	1.41e-19	GO:0031325	positive regulation of cellular metabolic process
1.51	2.41e-19	GO:0006996	organelle organization
1.61	3.31e-18	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.78	1.94e-17	GO:0002682	regulation of immune system process
1.61	1.97e-17	GO:0031328	positive regulation of cellular biosynthetic process
1.63	2.45e-17	GO:0010557	positive regulation of macromolecule biosynthetic process
1.32	3.66e-17	GO:0071840	cellular component organization or biogenesis
1.59	1.60e-16	GO:0009891	positive regulation of biosynthetic process
1.64	2.22e-16	GO:0010628	positive regulation of gene expression
1.55	3.09e-16	GO:0009892	negative regulation of metabolic process
1.93	3.42e-16	GO:0002684	positive regulation of immune system process
1.31	1.21e-15	GO:0016043	cellular component organization
2.12	3.10e-15	GO:0045321	leukocyte activation
1.56	3.63e-15	GO:0031324	negative regulation of cellular metabolic process
1.42	1.01e-14	GO:0048583	regulation of response to stimulus
1.55	1.43e-14	GO:0010605	negative regulation of macromolecule metabolic process
1.15	1.58e-14	GO:0050794	regulation of cellular process
1.57	3.66e-14	GO:0051173	positive regulation of nitrogen compound metabolic process
1.62	5.51e-14	GO:0045893	positive regulation of transcription, DNA-dependent
2.00	6.13e-14	GO:0001775	cell activation
1.53	6.81e-14	GO:0010941	regulation of cell death
1.61	1.19e-13	GO:0051254	positive regulation of RNA metabolic process
1.34	1.20e-13	GO:0044267	cellular protein metabolic process
1.34	1.35e-13	GO:0071841	cellular component organization or biogenesis at cellular level
1.53	2.69e-13	GO:0043067	regulation of programmed cell death
1.56	3.04e-13	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.55	3.79e-13	GO:0042127	regulation of cell proliferation
1.52	5.05e-13	GO:0042981	regulation of apoptosis
1.34	8.49e-13	GO:0071842	cellular component organization at cellular level
1.14	9.23e-13	GO:0050789	regulation of biological process
2.14	1.52e-12	GO:0046649	lymphocyte activation
1.59	1.92e-12	GO:0009890	negative regulation of biosynthetic process
1.61	3.70e-12	GO:0016265	death
1.73	3.89e-12	GO:0051276	chromosome organization
1.59	4.53e-12	GO:0031327	negative regulation of cellular biosynthetic process
1.13	5.62e-12	GO:0065007	biological regulation
1.37	5.63e-12	GO:0043412	macromolecule modification
1.63	6.54e-12	GO:0012501	programmed cell death
1.59	6.77e-12	GO:0010558	negative regulation of macromolecule biosynthetic process
1.25	8.84e-12	GO:0032502	developmental process
1.38	9.40e-12	GO:0006464	protein modification process
1.48	1.51e-11	GO:0035556	intracellular signal transduction
1.60	1.52e-11	GO:0008219	cell death
1.88	1.72e-11	GO:0016568	chromatin modification
1.63	2.53e-11	GO:0006915	apoptosis
1.30	2.73e-11	GO:0048731	system development
1.86	3.53e-11	GO:0050776	regulation of immune response
1.59	3.63e-11	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.28	4.70e-11	GO:0019538	protein metabolic process
1.80	4.79e-11	GO:0006955	immune response
1.65	5.03e-11	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.28	5.16e-11	GO:0048856	anatomical structure development
1.59	5.66e-11	GO:0010629	negative regulation of gene expression
1.35	6.67e-11	GO:0048513	organ development
1.58	1.03e-10	GO:0051172	negative regulation of nitrogen compound metabolic process
1.79	1.36e-10	GO:0006325	chromatin organization
1.57	2.33e-10	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59	2.50e-10	GO:0070887	cellular response to chemical stimulus
1.81	2.70e-10	GO:0002520	immune system development
1.65	3.75e-10	GO:0008284	positive regulation of cell proliferation
1.25	7.12e-10	GO:0007275	multicellular organismal development
1.93	1.45e-09	GO:0050778	positive regulation of immune response
1.58	1.85e-09	GO:0045892	negative regulation of transcription, DNA-dependent
2.16	2.29e-09	GO:0002521	leukocyte differentiation
1.58	2.58e-09	GO:0051253	negative regulation of RNA metabolic process
1.85	2.81e-09	GO:0030097	hemopoiesis
1.30	3.86e-09	GO:0048869	cellular developmental process
1.78	7.87e-09	GO:0048534	hemopoietic or lymphoid organ development
1.30	8.89e-09	GO:0030154	cell differentiation
1.49	1.17e-08	GO:0007049	cell cycle
1.35	1.82e-08	GO:0051239	regulation of multicellular organismal process
1.65	1.84e-08	GO:0051726	regulation of cell cycle
1.38	3.66e-08	GO:0009966	regulation of signal transduction
2.18	4.96e-08	GO:0002757	immune response-activating signal transduction
1.41	5.73e-08	GO:0050793	regulation of developmental process
2.15	7.52e-08	GO:0002764	immune response-regulating signaling pathway
1.42	8.41e-08	GO:0032268	regulation of cellular protein metabolic process
1.44	1.40e-07	GO:2000026	regulation of multicellular organismal development
1.37	1.52e-07	GO:0033036	macromolecule localization
1.74	1.94e-07	GO:0051098	regulation of binding
2.02	2.03e-07	GO:0002253	activation of immune response
1.46	3.27e-07	GO:0048584	positive regulation of response to stimulus
1.60	3.33e-07	GO:0071310	cellular response to organic substance
1.64	5.78e-07	GO:0032583	regulation of gene-specific transcription
1.94	6.04e-07	GO:0016569	covalent chromatin modification
1.95	6.38e-07	GO:0016570	histone modification
1.45	7.77e-07	GO:0045595	regulation of cell differentiation
1.57	8.53e-07	GO:0043068	positive regulation of programmed cell death
1.56	8.78e-07	GO:0010942	positive regulation of cell death
1.58	9.82e-07	GO:0043069	negative regulation of programmed cell death
2.04	1.01e-06	GO:0002252	immune effector process
1.57	1.19e-06	GO:0060548	negative regulation of cell death
1.59	1.22e-06	GO:0043066	negative regulation of apoptosis
2.09	1.64e-06	GO:0042110	T cell activation
1.37	2.31e-06	GO:0051246	regulation of protein metabolic process
1.55	2.89e-06	GO:0043065	positive regulation of apoptosis
1.79	3.63e-06	GO:0051101	regulation of DNA binding
1.98	3.80e-06	GO:0031349	positive regulation of defense response
2.01	4.31e-06	GO:0002696	positive regulation of leukocyte activation
1.30	4.47e-06	GO:0065009	regulation of molecular function
2.05	4.89e-06	GO:0051251	positive regulation of lymphocyte activation
1.85	5.25e-06	GO:0051249	regulation of lymphocyte activation
2.11	5.30e-06	GO:0030098	lymphocyte differentiation
1.47	5.84e-06	GO:0019220	regulation of phosphate metabolic process
1.47	5.84e-06	GO:0051174	regulation of phosphorus metabolic process
1.82	7.15e-06	GO:0030036	actin cytoskeleton organization
1.28	8.02e-06	GO:0006950	response to stress
1.78	8.60e-06	GO:0002694	regulation of leukocyte activation
1.78	8.60e-06	GO:0030029	actin filament-based process
1.37	8.87e-06	GO:0006796	phosphate metabolic process
1.43	9.08e-06	GO:0031399	regulation of protein modification process
1.96	1.11e-05	GO:0050867	positive regulation of cell activation
1.36	1.12e-05	GO:0006793	phosphorus metabolic process
1.72	1.16e-05	GO:0031347	regulation of defense response
1.46	1.63e-05	GO:0042325	regulation of phosphorylation
1.64	1.64e-05	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.75	1.95e-05	GO:0050865	regulation of cell activation
1.36	1.96e-05	GO:0008104	protein localization
2.71	2.23e-05	GO:0019882	antigen processing and presentation
1.56	2.34e-05	GO:0022403	cell cycle phase
1.40	2.46e-05	GO:0045184	establishment of protein localization
1.50	2.54e-05	GO:0051094	positive regulation of developmental process
1.46	2.63e-05	GO:0046907	intracellular transport
2.33	2.67e-05	GO:0042113	B cell activation
1.48	3.02e-05	GO:0001932	regulation of protein phosphorylation
1.55	3.48e-05	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.18	3.81e-05	GO:0051179	localization
1.76	4.32e-05	GO:0043193	positive regulation of gene-specific transcription
1.69	4.42e-05	GO:0008380	RNA splicing
1.53	4.53e-05	GO:0080134	regulation of response to stress
1.53	4.77e-05	GO:0007010	cytoskeleton organization
1.60	5.88e-05	GO:0016071	mRNA metabolic process
1.42	6.25e-05	GO:0006468	protein phosphorylation
1.85	6.46e-05	GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter
3.08	6.99e-05	GO:0002285	lymphocyte activation involved in immune response
1.28	7.85e-05	GO:0023051	regulation of signaling
1.62	8.43e-05	GO:0008283	cell proliferation
1.39	8.59e-05	GO:0015031	protein transport
1.66	8.72e-05	GO:0012502	induction of programmed cell death
1.57	9.07e-05	GO:0000278	mitotic cell cycle
1.48	1.09e-04	GO:0006396	RNA processing
1.68	1.16e-04	GO:0001817	regulation of cytokine production
1.45	1.26e-04	GO:0022402	cell cycle process
1.65	1.47e-04	GO:0006917	induction of apoptosis
1.54	1.58e-04	GO:0045597	positive regulation of cell differentiation
1.33	2.14e-04	GO:0032879	regulation of localization
1.74	2.32e-04	GO:0051090	regulation of sequence-specific DNA binding transcription factor activity
1.74	2.55e-04	GO:0006954	inflammatory response
1.58	2.80e-04	GO:0007243	intracellular protein kinase cascade
1.58	2.80e-04	GO:0023014	signal transduction via phosphorylation event
3.08	2.89e-04	GO:0046631	alpha-beta T cell activation
2.01	3.17e-04	GO:0045089	positive regulation of innate immune response
2.13	3.76e-04	GO:0001890	placenta development
1.90	4.15e-04	GO:0045088	regulation of innate immune response
2.47	4.36e-04	GO:0002263	cell activation involved in immune response
2.47	4.36e-04	GO:0002366	leukocyte activation involved in immune response
1.81	5.35e-04	GO:0002697	regulation of immune effector process
1.29	5.38e-04	GO:0050790	regulation of catalytic activity
1.73	5.46e-04	GO:0034097	response to cytokine stimulus
2.09	5.47e-04	GO:0002703	regulation of leukocyte mediated immunity
1.53	6.05e-04	GO:0010627	regulation of intracellular protein kinase cascade
1.36	6.10e-04	GO:0016310	phosphorylation
1.70	7.40e-04	GO:0090046	regulation of transcription regulator activity
1.51	7.54e-04	GO:0006974	response to DNA damage stimulus
1.35	8.11e-04	GO:0051649	establishment of localization in cell
1.62	9.35e-04	GO:0007264	small GTPase mediated signal transduction
2.49	9.46e-04	GO:0000082	G1/S transition of mitotic cell cycle
1.50	9.81e-04	GO:0032270	positive regulation of cellular protein metabolic process
1.99	9.83e-04	GO:0030099	myeloid cell differentiation
2.86	1.04e-03	GO:0048002	antigen processing and presentation of peptide antigen
1.46	1.06e-03	GO:0006259	DNA metabolic process
1.65	1.07e-03	GO:0010608	posttranscriptional regulation of gene expression
1.55	1.07e-03	GO:0051301	cell division
2.14	1.21e-03	GO:0002706	regulation of lymphocyte mediated immunity
1.69	1.41e-03	GO:0010564	regulation of cell cycle process
1.39	1.47e-03	GO:0033554	cellular response to stress
3.15	1.57e-03	GO:0019884	antigen processing and presentation of exogenous antigen
1.48	1.61e-03	GO:0051247	positive regulation of protein metabolic process
2.06	1.70e-03	GO:0002699	positive regulation of immune effector process
2.08	1.74e-03	GO:0045637	regulation of myeloid cell differentiation
1.85	1.89e-03	GO:0051169	nuclear transport
2.51	2.05e-03	GO:0050851	antigen receptor-mediated signaling pathway
1.30	2.10e-03	GO:0051641	cellular localization
1.26	2.44e-03	GO:0009653	anatomical structure morphogenesis
2.59	2.50e-03	GO:0030183	B cell differentiation
2.35	2.98e-03	GO:0002429	immune response-activating cell surface receptor signaling pathway
1.33	3.08e-03	GO:0051128	regulation of cellular component organization
1.22	3.26e-03	GO:0042221	response to chemical stimulus
1.62	3.31e-03	GO:0051056	regulation of small GTPase mediated signal transduction
1.32	3.61e-03	GO:0009888	tissue development
2.11	3.87e-03	GO:0002224	toll-like receptor signaling pathway
1.46	5.06e-03	GO:0051338	regulation of transferase activity
1.82	5.06e-03	GO:0006913	nucleocytoplasmic transport
2.28	5.10e-03	GO:0060326	cell chemotaxis
1.57	5.13e-03	GO:0018193	peptidyl-amino acid modification
2.03	5.22e-03	GO:0002218	activation of innate immune response
1.41	5.50e-03	GO:0044092	negative regulation of molecular function
1.56	6.14e-03	GO:0006397	mRNA processing
1.47	6.50e-03	GO:0043549	regulation of kinase activity
1.65	6.97e-03	GO:0046578	regulation of Ras protein signal transduction
1.81	7.19e-03	GO:0071345	cellular response to cytokine stimulus
1.78	7.22e-03	GO:0050863	regulation of T cell activation
1.91	7.39e-03	GO:0002237	response to molecule of bacterial origin
1.38	7.48e-03	GO:0040011	locomotion
1.28	7.56e-03	GO:0010033	response to organic substance
1.54	8.36e-03	GO:0033043	regulation of organelle organization
1.63	8.49e-03	GO:0006897	endocytosis
1.63	8.49e-03	GO:0010324	membrane invagination
1.47	9.03e-03	GO:0009611	response to wounding
1.48	1.04e-02	GO:0016477	cell migration
1.16	1.04e-02	GO:0051234	establishment of localization
2.02	1.12e-02	GO:0002221	pattern recognition receptor signaling pathway
2.65	1.13e-02	GO:0001776	leukocyte homeostasis
2.03	1.16e-02	GO:0030217	T cell differentiation
2.24	1.18e-02	GO:0002768	immune response-regulating cell surface receptor signaling pathway
2.20	1.22e-02	GO:0002756	MyD88-independent toll-like receptor signaling pathway
2.15	1.25e-02	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
1.49	1.44e-02	GO:0031401	positive regulation of protein modification process
1.51	1.47e-02	GO:0070647	protein modification by small protein conjugation or removal
1.49	1.51e-02	GO:0051130	positive regulation of cellular component organization
3.03	1.56e-02	GO:0046632	alpha-beta T cell differentiation
2.68	1.65e-02	GO:0002260	lymphocyte homeostasis
1.92	1.75e-02	GO:0019221	cytokine-mediated signaling pathway
1.82	1.86e-02	GO:0010638	positive regulation of organelle organization
2.43	1.93e-02	GO:0002573	myeloid leukocyte differentiation
1.46	2.09e-02	GO:0045859	regulation of protein kinase activity
1.61	2.12e-02	GO:0071900	regulation of protein serine/threonine kinase activity
2.37	2.15e-02	GO:0030595	leukocyte chemotaxis
1.97	2.19e-02	GO:0002758	innate immune response-activating signal transduction
1.61	2.36e-02	GO:0071495	cellular response to endogenous stimulus
1.90	2.37e-02	GO:0051325	interphase
1.81	2.43e-02	GO:0070663	regulation of leukocyte proliferation
2.87	2.46e-02	GO:0002200	somatic diversification of immune receptors
1.91	2.53e-02	GO:0051329	interphase of mitotic cell cycle
2.04	2.57e-02	GO:0006473	protein acetylation
1.81	2.64e-02	GO:0050670	regulation of lymphocyte proliferation
1.63	2.70e-02	GO:0032870	cellular response to hormone stimulus
1.66	2.71e-02	GO:0007346	regulation of mitotic cell cycle
2.11	2.73e-02	GO:0016573	histone acetylation
1.49	2.79e-02	GO:0051270	regulation of cellular component movement
2.60	3.05e-02	GO:0050764	regulation of phagocytosis
1.97	3.19e-02	GO:0002443	leukocyte mediated immunity
2.37	3.20e-02	GO:0032943	mononuclear cell proliferation
1.59	3.39e-02	GO:0010562	positive regulation of phosphorus metabolic process
1.59	3.39e-02	GO:0045937	positive regulation of phosphate metabolic process
1.89	3.42e-02	GO:0018205	peptidyl-lysine modification
1.80	3.45e-02	GO:0032944	regulation of mononuclear cell proliferation
1.16	3.45e-02	GO:0006810	transport
1.38	3.62e-02	GO:0006952	defense response
1.72	3.80e-02	GO:0051099	positive regulation of binding
2.11	4.03e-02	GO:0001892	embryonic placenta development
2.13	4.06e-02	GO:0001816	cytokine production
1.93	4.14e-02	GO:0043543	protein acylation
3.41	4.27e-02	GO:0002286	T cell activation involved in immune response
3.41	4.27e-02	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I
1.62	4.50e-02	GO:0001934	positive regulation of protein phosphorylation
1.57	4.91e-02	GO:0051129	negative regulation of cellular component organization

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.52	1.92e-94	GO:0005634	nucleus
1.26	3.70e-89	GO:0005622	intracellular
1.26	2.09e-83	GO:0044424	intracellular part
1.28	1.06e-72	GO:0043226	organelle
1.28	2.54e-72	GO:0043229	intracellular organelle
1.30	4.54e-71	GO:0043227	membrane-bounded organelle
1.30	1.94e-70	GO:0043231	intracellular membrane-bounded organelle
1.10	5.53e-35	GO:0005623	cell
1.10	5.53e-35	GO:0044464	cell part
1.58	2.01e-33	GO:0044428	nuclear part
1.57	1.44e-25	GO:0031981	nuclear lumen
1.18	2.70e-23	GO:0005737	cytoplasm
1.29	1.50e-22	GO:0044446	intracellular organelle part
1.65	1.72e-22	GO:0005654	nucleoplasm
1.28	1.79e-22	GO:0044422	organelle part
1.32	1.86e-21	GO:0032991	macromolecular complex
1.47	1.93e-20	GO:0043233	organelle lumen
1.47	2.18e-20	GO:0070013	intracellular organelle lumen
1.46	2.90e-20	GO:0031974	membrane-enclosed lumen
1.34	3.72e-19	GO:0043234	protein complex
1.66	6.80e-15	GO:0044451	nucleoplasm part
1.40	6.05e-13	GO:0005829	cytosol
1.26	2.38e-09	GO:0043228	non-membrane-bounded organelle
1.26	2.38e-09	GO:0043232	intracellular non-membrane-bounded organelle
1.62	1.55e-08	GO:0005694	chromosome
1.60	3.34e-07	GO:0044427	chromosomal part
4.07	4.24e-07	GO:0031519	PcG protein complex
1.13	2.51e-06	GO:0044444	cytoplasmic part
1.78	9.13e-06	GO:0000785	chromatin
1.76	2.31e-05	GO:0000228	nuclear chromosome
1.72	5.51e-05	GO:0009897	external side of plasma membrane
1.73	3.54e-04	GO:0044454	nuclear chromosome part
1.54	7.72e-04	GO:0005667	transcription factor complex
1.69	1.12e-03	GO:0005635	nuclear envelope
1.97	1.32e-03	GO:0000790	nuclear chromatin
1.43	1.63e-03	GO:0005768	endosome
1.23	1.65e-03	GO:0005856	cytoskeleton
1.13	2.10e-03	GO:0071944	cell periphery
1.75	2.26e-03	GO:0005938	cell cortex
1.41	2.29e-03	GO:0009986	cell surface
1.57	3.18e-03	GO:0000323	lytic vacuole
1.57	3.18e-03	GO:0005764	lysosome
1.74	6.83e-03	GO:0016604	nuclear body
2.40	2.12e-02	GO:0000118	histone deacetylase complex
4.04	2.44e-02	GO:0035098	ESC/E(Z) complex
1.91	2.62e-02	GO:0016585	chromatin remodeling complex
2.18	2.62e-02	GO:0005884	actin filament
1.12	2.84e-02	GO:0005886	plasma membrane
1.57	2.95e-02	GO:0045121	membrane raft
1.27	3.34e-02	GO:0012505	endomembrane system
1.25	3.58e-02	GO:0044430	cytoskeletal part

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.22	5.74e-61	GO:0005488	binding
1.35	1.45e-50	GO:0005515	protein binding
1.53	7.38e-44	GO:0003676	nucleic acid binding
1.58	1.35e-33	GO:0003677	DNA binding
1.68	3.01e-22	GO:0030528	transcription regulator activity
1.71	1.09e-16	GO:0043565	sequence-specific DNA binding
1.64	1.42e-15	GO:0001071	nucleic acid binding transcription factor activity
1.64	1.42e-15	GO:0003700	sequence-specific DNA binding transcription factor activity
1.89	1.03e-11	GO:0008134	transcription factor binding
1.30	1.74e-10	GO:0000166	nucleotide binding
1.83	2.02e-10	GO:0016564	transcription repressor activity
1.38	3.41e-10	GO:0008270	zinc ion binding
1.53	7.14e-10	GO:0003723	RNA binding
1.77	3.00e-09	GO:0016563	transcription activator activity
1.32	1.00e-08	GO:0046914	transition metal ion binding
1.45	1.01e-08	GO:0019899	enzyme binding
1.29	1.66e-07	GO:0035639	purine ribonucleoside triphosphate binding
1.88	4.24e-07	GO:0003682	chromatin binding
1.27	6.36e-07	GO:0032553	ribonucleotide binding
1.27	8.36e-07	GO:0032555	purine ribonucleotide binding
1.27	1.08e-06	GO:0017076	purine nucleotide binding
1.84	1.23e-06	GO:0000975	regulatory region DNA binding
1.84	1.23e-06	GO:0001067	regulatory region nucleic acid binding
1.84	1.23e-06	GO:0044212	transcription regulatory region DNA binding
1.82	7.74e-06	GO:0010843	promoter binding
1.36	1.07e-05	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.17	2.61e-05	GO:0043167	ion binding
1.17	3.52e-05	GO:0043169	cation binding
1.37	6.29e-05	GO:0016301	kinase activity
1.53	6.66e-05	GO:0030695	GTPase regulator activity
1.37	6.81e-05	GO:0042802	identical protein binding
1.16	7.61e-05	GO:0046872	metal ion binding
1.75	7.76e-05	GO:0005096	GTPase activator activity
1.39	8.29e-05	GO:0046983	protein dimerization activity
1.59	1.16e-04	GO:0008047	enzyme activator activity
1.59	1.60e-04	GO:0019900	kinase binding
1.26	2.45e-04	GO:0005524	ATP binding
1.50	2.60e-04	GO:0060589	nucleoside-triphosphatase regulator activity
1.24	6.82e-04	GO:0032559	adenyl ribonucleotide binding
1.69	8.13e-04	GO:0043566	structure-specific DNA binding
1.36	8.23e-04	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.24	8.55e-04	GO:0030554	adenyl nucleotide binding
1.60	1.47e-03	GO:0019901	protein kinase binding
1.21	1.58e-03	GO:0016740	transferase activity
1.31	2.20e-03	GO:0030234	enzyme regulator activity
2.05	3.01e-03	GO:0035257	nuclear hormone receptor binding
1.38	3.53e-03	GO:0004672	protein kinase activity
1.78	3.96e-03	GO:0003690	double-stranded DNA binding
1.43	5.52e-03	GO:0004674	protein serine/threonine kinase activity
1.26	1.21e-02	GO:0005102	receptor binding
1.65	1.42e-02	GO:0005126	cytokine receptor binding
2.45	1.60e-02	GO:0042379	chemokine receptor binding
1.97	1.80e-02	GO:0003705	sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.59	2.04e-02	GO:0019787	small conjugating protein ligase activity
1.35	2.14e-02	GO:0019904	protein domain specific binding
1.52	2.30e-02	GO:0005083	small GTPase regulator activity
1.87	2.57e-02	GO:0051427	hormone receptor binding
1.43	3.83e-02	GO:0005525	GTP binding
2.40	3.97e-02	GO:0004715	non-membrane spanning protein tyrosine kinase activity
1.59	4.24e-02	GO:0004842	ubiquitin-protein ligase activity
1.41	4.50e-02	GO:0032403	protein complex binding
1.90	4.58e-02	GO:0005099	Ras GTPase activator activity