Motif ID: SPZ1.p2

Z-value: 1.285


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
Spz1 79401 spermatogenic leucine zipper 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Spz1chr13_-_933461260.121.2e-01Click!


Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_73509668 13.015 Rtn1
reticulon 1
chr12_-_73509537 11.675 Rtn1
reticulon 1
chr14_+_66587319 10.656 NM_013492
 Clu
clusterin
chr15_+_91881593 10.069 NM_001159648
 Cntn1
contactin 1
chr4_+_129662284 9.334 NM_173071
 Bai2
brain-specific angiogenesis inhibitor 2
chr4_+_104040160 8.583 NM_010014
NM_177259
 Dab1

disabled homolog 1 (Drosophila)

chr9_-_29219382 8.122 Ntm
neurotrimin
chr9_-_86775282 8.032 Snap91
synaptosomal-associated protein 91
chr10_-_108447894 7.911 Syt1
synaptotagmin I
chr9_-_86775154 7.819 NM_013669
 Snap91
synaptosomal-associated protein 91
chr11_+_98629709 7.657


chr2_+_28048779 7.515 Olfm1
olfactomedin 1
chr10_-_108448003 6.976 Syt1
synaptotagmin I
chr4_+_129662110 6.972 Bai2
brain-specific angiogenesis inhibitor 2
chr6_-_119280616 6.865 NM_172492
 Lrtm2
leucine-rich repeats and transmembrane domains 2
chr14_-_55734213 6.654 NM_001003829
 Jph4
junctophilin 4
chr4_-_41587115 6.640 Enho
energy homeostasis associated
chr6_-_113841295 6.534 Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr7_+_53651811 6.517 NM_008421
NM_001112739
 Kcnc1

potassium voltage gated channel, Shaw-related subfamily, member 1

chr9_-_44688946 6.319 Mll1
myeloid/lymphoid or mixed-lineage leukemia 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 108 entries
Enrichment   P-value GO Accession GO Term
2.82 1.19e-02 GO:0043401 steroid hormone mediated signaling pathway
2.66 1.43e-02 GO:0006754 ATP biosynthetic process
2.55 8.18e-03 GO:0009755 hormone-mediated signaling pathway
2.44 2.12e-02 GO:0009142 nucleoside triphosphate biosynthetic process
2.42 3.94e-02 GO:0009145 purine nucleoside triphosphate biosynthetic process
2.12 3.95e-03 GO:0043087 regulation of GTPase activity
2.11 4.96e-03 GO:0033124 regulation of GTP catabolic process
2.09 4.67e-02 GO:0032318 regulation of Ras GTPase activity
2.04 4.16e-03 GO:0030811 regulation of nucleotide catabolic process
2.04 4.16e-03 GO:0033121 regulation of purine nucleotide catabolic process
1.96 1.44e-05 GO:0048812 neuron projection morphogenesis
1.94 2.18e-04 GO:0007409 axonogenesis
1.90 7.22e-07 GO:0019226 transmission of nerve impulse
1.90 7.22e-07 GO:0035637 multicellular organismal signaling
1.90 1.11e-06 GO:0031175 neuron projection development
1.89 7.66e-05 GO:0007268 synaptic transmission
1.89 5.00e-03 GO:0050804 regulation of synaptic transmission
1.88 2.16e-06 GO:0009894 regulation of catabolic process
1.88 3.33e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.86 3.52e-02 GO:0042391 regulation of membrane potential

Gene overrepresentation in compartment category:

Showing 1 to 20 of 36 entries
Enrichment   P-value GO Accession GO Term
3.66 4.49e-02 GO:0080008 CUL4 RING ubiquitin ligase complex
2.96 3.55e-03 GO:0042734 presynaptic membrane
2.74 4.66e-03 GO:0043204 perikaryon
2.29 8.94e-06 GO:0033267 axon part
2.20 6.69e-11 GO:0030424 axon
2.04 1.44e-04 GO:0045211 postsynaptic membrane
2.00 1.32e-09 GO:0043025 neuronal cell body
1.99 8.42e-10 GO:0044297 cell body
1.92 2.72e-08 GO:0044456 synapse part
1.89 9.72e-12 GO:0045202 synapse
1.85 1.15e-12 GO:0043005 neuron projection
1.73 3.77e-04 GO:0030425 dendrite
1.67 1.03e-08 GO:0030054 cell junction
1.64 8.69e-05 GO:0044463 cell projection part
1.53 7.57e-10 GO:0042995 cell projection
1.44 3.37e-04 GO:0031982 vesicle
1.43 7.66e-05 GO:0005624 membrane fraction
1.42 5.36e-05 GO:0005626 insoluble fraction
1.42 6.26e-05 GO:0005794 Golgi apparatus
1.39 8.46e-03 GO:0031410 cytoplasmic vesicle

Gene overrepresentation in function category:

Showing 1 to 20 of 37 entries
Enrichment   P-value GO Accession GO Term
3.87 4.37e-02 GO:0015079 potassium ion transmembrane transporter activity
2.63 1.82e-02 GO:0003707 steroid hormone receptor activity
2.58 2.57e-02 GO:0004879 ligand-dependent nuclear receptor activity
2.55 5.41e-03 GO:0042625 ATPase activity, coupled to transmembrane movement of ions
2.19 3.92e-04 GO:0005516 calmodulin binding
2.04 1.73e-07 GO:0005083 small GTPase regulator activity
1.79 2.15e-02 GO:0005244 voltage-gated ion channel activity
1.79 2.15e-02 GO:0022832 voltage-gated channel activity
1.75 5.24e-04 GO:0022836 gated channel activity
1.72 6.29e-06 GO:0060589 nucleoside-triphosphatase regulator activity
1.71 1.94e-05 GO:0030695 GTPase regulator activity
1.70 6.75e-03 GO:0005261 cation channel activity
1.58 2.32e-04 GO:0008324 cation transmembrane transporter activity
1.58 3.13e-02 GO:0008047 enzyme activator activity
1.57 8.10e-03 GO:0005216 ion channel activity
1.53 1.44e-02 GO:0022803 passive transmembrane transporter activity
1.53 1.95e-02 GO:0022838 substrate-specific channel activity
1.52 2.26e-02 GO:0015267 channel activity
1.51 2.39e-03 GO:0008092 cytoskeletal protein binding
1.48 3.96e-04 GO:0015075 ion transmembrane transporter activity