Motif ID: STAT5{A,B}.p2

Z-value: 0.852


Transcription factors associated with STAT5{A,B}.p2:

Gene SymbolEntrez IDGene Name
Stat5a 20850 signal transducer and activator of transcription 5A
Stat5b 20851 signal transducer and activator of transcription 5B

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Stat5achr11_+_100721765-0.231.4e-03Click!
Stat5bchr11_-_1007117850.082.6e-01Click!


Activity profile for motif STAT5{A,B}.p2.

activity profile for motif STAT5{A,B}.p2


Sorted Z-values histogram for motif STAT5{A,B}.p2

Sorted Z-values for motif STAT5{A,B}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5{A,B}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_49184445 8.037 NM_001161516
Dctd
dCMP deaminase
chr7_-_11080687 6.567 NM_009577
Zik1
zinc finger protein interacting with K protein 1
chr8_-_126383327 6.462 1700054N08Rik
RIKEN cDNA 1700054N08 gene
chr7_+_25055436 5.812 NM_009567
Zfp93
zinc finger protein 93
chr2_+_128926721 5.797 NM_009086
Polr1b
polymerase (RNA) I polypeptide B
chr17_-_43803963 5.097 NM_028711
Slc25a27
solute carrier family 25, member 27
chr11_-_6167720 5.015 NM_026538
Ddx56
DEAD (Asp-Glu-Ala-Asp) box polypeptide 56
chr2_-_156817751 4.957 NM_013865
NM_180956
Ndrg3

N-myc downstream regulated gene 3

chr13_-_111070392 4.616 NM_023852
Rab3c
RAB3C, member RAS oncogene family
chr6_-_77929685 4.583 Ctnna2
catenin (cadherin associated protein), alpha 2
chr2_-_42509117 4.448 NM_053011
Lrp1b
low density lipoprotein-related protein 1B (deleted in tumors)
chr12_+_107248419 4.300 NM_001029843
NM_001029844
NM_011705
Vrk1


vaccinia related kinase 1


chr4_+_131864590 4.279 Snhg12
small nucleolar RNA host gene 12
chr13_-_111070344 4.263 Rab3c
RAB3C, member RAS oncogene family
chr18_-_70689894 4.194 NM_011972
Poli
polymerase (DNA directed), iota
chr19_+_57527393 4.175 NM_028115
NM_029839
Trub1

TruB pseudouridine (psi) synthase homolog 1 (E. coli)

chr19_-_4012654 4.094 Ndufv1
NADH dehydrogenase (ubiquinone) flavoprotein 1
chr11_+_78312621 4.010 NM_011707
Vtn
vitronectin
chr18_-_70689871 4.002 Poli
polymerase (DNA directed), iota
chr18_-_70689791 3.934 NM_001136090
Poli
polymerase (DNA directed), iota
chr19_-_4012698 3.931 NM_133666
Ndufv1
NADH dehydrogenase (ubiquinone) flavoprotein 1
chr6_-_77929660 3.853 NM_001109764
NM_009819
NM_145732
Ctnna2


catenin (cadherin associated protein), alpha 2


chr4_-_49533914 3.801 NM_178603
Mrpl50
mitochondrial ribosomal protein L50
chr2_-_42508486 3.789 Lrp1b
low density lipoprotein-related protein 1B (deleted in tumors)
chr7_-_107810868 3.745 NM_001163182
NM_013746
Plekhb1

pleckstrin homology domain containing, family B (evectins) member 1

chr12_+_107248496 3.744 Vrk1
vaccinia related kinase 1
chr11_-_50745128 3.664 NM_013744
Zfp354b
zinc finger protein 354B
chr11_-_21471767 3.525 Mdh1
malate dehydrogenase 1, NAD (soluble)
chr19_+_57527417 3.486 Trub1
TruB pseudouridine (psi) synthase homolog 1 (E. coli)
chr3_+_96962930 3.452 Acp6
acid phosphatase 6, lysophosphatidic
chr7_-_135604669 3.444 Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr11_+_69867869 3.376 NM_009714
Asgr1
asialoglycoprotein receptor 1
chr11_-_79317471 3.373 Omg
oligodendrocyte myelin glycoprotein
chr18_+_75178416 3.277 NM_027727
Dym
dymeclin
chr11_-_21471829 3.247 NM_008618
Mdh1
malate dehydrogenase 1, NAD (soluble)
chr11_+_95528269 3.235 NM_008831
Phb
prohibitin
chr8_+_113443764 3.202 NM_009179
St3gal2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr7_+_24919177 3.197 NM_019941
Zfp235
zinc finger protein 235
chr7_+_24897332 3.189 NM_021307
Zfp112
zinc finger protein 112
chr5_-_5514729 3.186 Cldn12
claudin 12
chr7_-_25101619 3.164 NM_009568
Zfp94
zinc finger protein 94
chr1_-_75250520 3.033 Ptprn
protein tyrosine phosphatase, receptor type, N
chr7_-_149361909 3.004 NM_027844
Krtap5-2
keratin associated protein 5-2
chr2_-_127410404 2.961 NM_001111029
NM_028141
Zfp661

zinc finger protein 661

chr7_-_135605026 2.959 NM_009383
Tial1
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr7_+_150255257 2.876 NM_001115085
NM_020285
NM_138631
Tssc4


tumor-suppressing subchromosomal transferable fragment 4


chr6_-_128374893 2.836 NM_133927
Itfg2
integrin alpha FG-GAP repeat containing 2
chr7_+_24866915 2.821 NM_001045486
Zfp180
zinc finger protein 180
chr5_-_5514787 2.792 NM_001193660
NM_001193659
NM_001193661
NM_022890
Cldn12



claudin 12



chr18_+_75178449 2.776 Dym
dymeclin
chr4_-_74924159 2.699 NM_025849
3110001D03Rik
RIKEN cDNA 3110001D03 gene
chr1_-_78440233 2.658 Farsb
phenylalanyl-tRNA synthetase, beta subunit
chr11_+_69867893 2.549 Asgr1
asialoglycoprotein receptor 1
chr6_-_128374944 2.531 Itfg2
integrin alpha FG-GAP repeat containing 2
chr2_+_177910053 2.480 NM_001177791
Phactr3
phosphatase and actin regulator 3
chr7_+_30601080 2.477 NM_001145880
NM_146185
Zfp790

zinc finger protein 790

chr7_+_25039812 2.455 NM_018791
Zfp108
zinc finger protein 108
chr15_-_11329372 2.433 Tars
threonyl-tRNA synthetase
chr4_+_49534088 2.425 NM_145547
Zfp189
zinc finger protein 189
chr18_-_33623069 2.350 NM_001109990
D0H4S114
DNA segment, human D4S114
chr2_-_113669229 2.339 Scg5
secretogranin V
chr11_+_78312784 2.239 Vtn
vitronectin
chr16_-_18812064 2.218 NM_009862
Cdc45
cell division cycle 45 homolog (S. cerevisiae)
chr8_+_96561180 2.167 Ogfod1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr1_-_172487240 2.122 NM_027528
Nos1ap
nitric oxide synthase 1 (neuronal) adaptor protein
chr15_-_11329374 2.073 Tars
threonyl-tRNA synthetase
chr9_-_122775060 2.036 NM_173364
Zfp445
zinc finger protein 445
chr7_-_112730004 2.034 NM_009685
Apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1
chr8_+_93837422 2.024 NM_011936
Fto
fat mass and obesity associated
chr15_-_11329379 2.001 Tars
threonyl-tRNA synthetase
chr15_-_11329310 1.872 Tars
threonyl-tRNA synthetase
chr15_-_11329385 1.801 NM_033074
Tars
threonyl-tRNA synthetase
chr13_-_111070225 1.738 Rab3c
RAB3C, member RAS oncogene family
chr9_+_35367050 1.698 NM_023292
Pus3
pseudouridine synthase 3
chr5_+_53225301 1.690 NM_024213
Anapc4
anaphase promoting complex subunit 4
chr7_-_110401018 1.672 NM_001001559
Dub2a
deubiquitinating enzyme 2a
chr8_+_73988823 1.655 NM_053162
Mrpl34
mitochondrial ribosomal protein L34
chr7_-_13639862 1.650 NM_145819
Mzf1
myeloid zinc finger 1
chr14_+_31699648 1.635 NM_001159299
NM_018746
Itih4

inter alpha-trypsin inhibitor, heavy chain 4

chr19_+_36908682 1.623 NM_001163635
Tnks2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr2_+_51893618 1.606 NM_009398
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr18_-_78006524 1.582 Haus1
HAUS augmin-like complex, subunit 1
chr15_-_44259378 1.572 Nudcd1
NudC domain containing 1
chrX_-_7829333 1.559 NM_133991
Ftsj1
FtsJ homolog 1 (E. coli)
chr18_-_78006491 1.557 NM_146089
Haus1
HAUS augmin-like complex, subunit 1
chr11_-_99712918 1.551 NM_001013823
Krtap4-16
keratin associated protein 4-16
chr14_-_55585407 1.542 Myh6
myosin, heavy polypeptide 6, cardiac muscle, alpha
chr2_-_102026486 1.477 NM_178886
Ldlrad3
low density lipoprotein receptor class A domain containing 3
chr5_-_86947601 1.461 NM_177162
9930032O22Rik
RIKEN cDNA 9930032O22 gene
chr16_-_91619237 1.458 NM_001099738
NM_138664
Dnajc28

DnaJ (Hsp40) homolog, subfamily C, member 28

chr11_-_50655047 1.457 NM_173387
Zfp879
zinc figer protein 879
chr8_-_85297983 1.429 NM_145600
Zfp330
zinc finger protein 330
chr9_+_26807281 1.414 Thyn1
thymocyte nuclear protein 1
chr11_-_120657647 1.381 NM_026824
Dus1l
dihydrouridine synthase 1-like (S. cerevisiae)
chr4_-_24778203 1.380 NM_001033531
NM_001163020
Klhl32

kelch-like 32 (Drosophila)

chr18_-_33623287 1.348 NM_053078
D0H4S114
DNA segment, human D4S114
chr8_+_96561162 1.318 Ogfod1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr6_+_13821522 1.311 1110019D14Rik
RIKEN cDNA 1110019D14 gene
chr8_+_24145593 1.296 Ank1
ankyrin 1, erythroid
chr17_-_85463965 1.284


chr11_+_50872758 1.275 NM_009329
Zfp354a
zinc finger protein 354A
chr8_-_112132522 1.253 NM_020046
Dhodh
dihydroorotate dehydrogenase
chr15_-_97816006 1.251 Col2a1
collagen, type II, alpha 1
chr6_-_89545534 1.242 NM_001167736
NM_025351
Chchd6

coiled-coil-helix-coiled-coil-helix domain containing 6

chr16_-_22657283 1.233 NM_138650
Dgkg
diacylglycerol kinase, gamma
chr8_+_107800370 1.224 Nol3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr8_-_112132276 1.186 Dhodh
dihydroorotate dehydrogenase
chr16_+_10545479 1.186 NM_177562
Clec16a
C-type lectin domain family 16, member A
chr7_+_30768973 1.172 NM_001033355
NM_001167872
NM_001167873
Zfp568


zinc finger protein 568


chr15_-_77759356 1.163 NM_019913
Txn2
thioredoxin 2
chr18_+_37179802 1.149 NM_138663
Pcdha12
protocadherin alpha 12
chr1_-_38851746 1.138 Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr2_+_120229988 1.129 Ganc
glucosidase, alpha; neutral C
chr14_-_55585412 1.119 NM_001164171
NM_010856
Myh6

myosin, heavy polypeptide 6, cardiac muscle, alpha

chr13_-_67856070 1.117 NM_001001130
Zfp85-rs1
zinc finger protein 85, related sequence 1
chr16_-_22657245 1.108 Dgkg
diacylglycerol kinase, gamma
chr9_+_19426528 1.108 NM_172918
Zfp317
zinc finger protein 317
chr3_+_96962693 1.107 NM_019800
Acp6
acid phosphatase 6, lysophosphatidic
chr10_+_127691166 1.093 NM_133996
Apon
apolipoprotein N
chr3_+_82830071 1.092 NM_001111048
NM_010196
Fga

fibrinogen alpha chain

chr5_+_53225253 1.070 Anapc4
anaphase promoting complex subunit 4
chr12_+_89599244 1.033 NM_028105
Adck1
aarF domain containing kinase 1
chr5_+_110539283 0.996 Zfp605
zinc finger protein 605
chr18_+_42435006 0.969 NM_172626
Rbm27
RNA binding motif protein 27
chr5_+_111032523 0.932 NM_001122639
Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr7_+_30880094 0.932 NM_011981
Zfp260
zinc finger protein 260
chr3_+_152009483 0.923 Usp33
ubiquitin specific peptidase 33
chr5_+_110539110 0.901 NM_001163996
Zfp605
zinc finger protein 605
chr17_+_85025803 0.901 Dync2li1
dynein cytoplasmic 2 light intermediate chain 1
chr19_-_10278231 0.899 NM_007999
Fen1
flap structure specific endonuclease 1
chr8_-_87211726 0.883 NM_025788
Nacc1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr2_+_152673699 0.881 NM_001141975
NM_001141976
NM_001141977
NM_001141978
NM_028109
Tpx2




TPX2, microtubule-associated protein homolog (Xenopus laevis)




chr5_-_23929349 0.873 Cdk5
cyclin-dependent kinase 5
chr7_+_112005496 0.858 NM_007887
Dub1
deubiquitinating enzyme 1
chr3_-_90294832 0.856 NM_133854
Snapin
SNAP-associated protein
chr10_-_126959397 0.837 Shmt2
serine hydroxymethyltransferase 2 (mitochondrial)
chr8_+_73920737 0.823 NM_026636
5430437P03Rik
RIKEN cDNA 5430437P03 gene
chr3_+_152009436 0.818 NM_001076676
NM_133247
Usp33

ubiquitin specific peptidase 33

chr11_+_49016828 0.814 NM_001024846
NM_009562
Zfp62

zinc finger protein 62

chr1_+_120218417 0.813 NM_026472
Mki67ip
Mki67 (FHA domain) interacting nucleolar phosphoprotein
chr1_+_79772668 0.813 Mrpl44
mitochondrial ribosomal protein L44
chr13_-_67710581 0.809 AA987161
expressed sequence AA987161
chr3_-_92242684 0.807 NM_009265
Sprr1b
small proline-rich protein 1B
chr5_-_115934305 0.794 NM_001167691
NM_133760
Sirt4

sirtuin 4 (silent mating type information regulation 2 homolog) 4 (S. cerevisiae)

chr15_+_57743727 0.791 NM_001081396
NM_001167679
Wdr67

WD repeat domain 67

chr3_-_10440061 0.776 NM_001127191
NM_029068
Snx16

sorting nexin 16

chr6_-_33010151 0.774 NM_025336
Chchd3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr10_+_79606611 0.773 Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr8_-_96560811 0.765 NM_026623
Nudt21
nudix (nucleoside diphosphate linked moiety X)-type motif 21
chr17_+_56749361 0.763


chr3_-_95708543 0.760 NM_011797
Car14
carbonic anhydrase 14
chr18_-_42421635 0.758 NM_134137
Lars
leucyl-tRNA synthetase
chr16_-_18811669 0.754 NM_001161623
Cdc45
cell division cycle 45 homolog (S. cerevisiae)
chr15_+_76875584 0.752 NM_028010
Apol6
apolipoprotein L 6
chr13_-_67585160 0.747 NM_001076791
Zfp874b
zinc finger protein 874b
chr17_-_24769539 0.734 Tsc2
tuberous sclerosis 2
chr7_+_53039094 0.731 Lmtk3
lemur tyrosine kinase 3
chr13_-_67182447 0.728 NM_001012448
Zfp708
zinc finger protein 708
chr5_+_31829709 0.721 Slc4a1ap
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr9_+_26807258 0.718 NM_144543
Thyn1
thymocyte nuclear protein 1
chr6_+_38331516 0.709 NM_153600
Ttc26
tetratricopeptide repeat domain 26
chr7_-_28764157 0.707 NM_001081021
Zfp780b
zinc finger protein 780B
chr1_+_59741800 0.706 NM_018868
Nop58
NOP58 ribonucleoprotein homolog (yeast)
chr10_+_40069113 0.692 NM_001168304
NM_198164
Cdk19

cyclin-dependent kinase 19

chr5_-_104340164 0.687 NM_178741
Klhl8
kelch-like 8 (Drosophila)
chr8_+_96561135 0.682 Ogfod1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr4_+_140256449 0.677 Rcc2
regulator of chromosome condensation 2
chr5_+_151755181 0.673 NM_013823
Kl
klotho
chr4_-_41450064 0.665 NM_001085515
AI464131
expressed sequence AI464131
chr17_+_24769624 0.653 NM_008743
Nthl1
nth (endonuclease III)-like 1 (E.coli)
chr15_+_44259636 0.651 NM_175009
Eny2
enhancer of yellow 2 homolog (Drosophila)
chr15_+_79963548 0.651 NM_025609
Tab1
TGF-beta activated kinase 1/MAP3K7 binding protein 1
chr5_-_31829101 0.634 NM_028150
Supt7l
suppressor of Ty 7 (S. cerevisiae)-like
chr12_+_89598984 0.633 Adck1
aarF domain containing kinase 1
chr15_+_44455984 0.612 Ebag9
estrogen receptor-binding fragment-associated gene 9
chr13_-_67476668 0.600 NM_001001186
Zfp456
zinc finger protein 456
chr7_+_53039273 0.596 NM_001005511
Lmtk3
lemur tyrosine kinase 3
chr4_-_116794923 0.595 Btbd19
BTB (POZ) domain containing 19
chr11_+_70461024 0.595 NM_027445
Rnf167
ring finger protein 167
chr8_-_107850154 0.592 NM_177449
Lrrc29
leucine rich repeat containing 29
chr10_+_31033188 0.592 NM_027168
Hddc2
HD domain containing 2
chr7_-_7089433 0.590 NM_029584
Zfp773
zinc finger protein 773
chr13_-_67370003 0.585 NM_001001152
Zfp458
zinc finger protein 458
chr9_+_74918979 0.579 NM_010864
Myo5a
myosin VA
chr11_-_47192793 0.563 NM_011891
Sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr9_+_21400165 0.560


chr18_-_32071556 0.559 NM_026006
Sft2d3
SFT2 domain containing 3
chr7_-_30638635 0.554 NM_173738
Zfp940
zinc finger protein 940
chr17_+_56396215 0.550 NM_010192
Fem1a
feminization 1 homolog a (C. elegans)
chr16_+_29209780 0.540 NM_013751
Hrasls
HRAS-like suppressor
chr5_-_31829057 0.539 Supt7l
suppressor of Ty 7 (S. cerevisiae)-like
chr8_-_108282498 0.538 NM_027469
Gfod2
glucose-fructose oxidoreductase domain containing 2
chr6_-_148719426 0.514 Ipo8
importin 8
chr14_-_66452720 0.513 NM_028039
Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr8_+_90661746 0.505 NM_172757
Heatr3
HEAT repeat containing 3
chr10_+_40069255 0.503 Cdk19
cyclin-dependent kinase 19
chr7_+_107621474 0.503 NM_009464
Ucp3
uncoupling protein 3 (mitochondrial, proton carrier)
chr8_+_107800316 0.498 NM_030152
Nol3
nucleolar protein 3 (apoptosis repressor with CARD domain)
chr4_+_131399376 0.497 NM_025297
Mecr
mitochondrial trans-2-enoyl-CoA reductase
chr7_+_3581586 0.491 NM_001159714
NM_027328
Prpf31

PRP31 pre-mRNA processing factor 31 homolog (yeast)


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.67 8.14e-04 GO:0043169 cation binding
1.67 9.30e-04 GO:0043167 ion binding
1.67 1.06e-03 GO:0046872 metal ion binding