Motif ID: TBP.p2

Z-value: 3.761


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
Tbp 21374 TATA box binding protein

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tbpchr17_+_15636851-0.473.5e-11Click!


Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_101834741 90.409 Krt8
keratin 8
chr15_-_101834744 82.053 Krt8
keratin 8
chr15_-_101834713 76.831 Krt8
keratin 8
chr15_-_101834746 76.731 NM_031170
 Krt8
keratin 8
chr5_+_136363810 67.050 Hspb1
heat shock protein 1
chr11_+_94797565 60.869 NM_007742
 Col1a1
collagen, type I, alpha 1
chr6_+_4455686 58.562 NM_007743
 Col1a2
collagen, type I, alpha 2
chr6_+_55286292 56.840 NM_007472
 Aqp1
aquaporin 1
chr6_-_136824323 52.886 NM_008597
 Mgp
matrix Gla protein
chr10_+_43298969 51.325 NM_009846
 Cd24a
CD24a antigen
chr8_-_126418628 50.392 NM_009606
 Acta1
actin, alpha 1, skeletal muscle
chr7_-_106501620 47.612 Serpinh1
serine (or cysteine) peptidase inhibitor, clade H, member 1
chr16_-_14291427 47.527 NM_001161775
NM_013607
 Myh11

myosin, heavy polypeptide 11, smooth muscle

chr9_+_50561315 44.935 Cryab
crystallin, alpha B
chr3_-_10208575 44.036 NM_024406
 Fabp4
fatty acid binding protein 4, adipocyte
chr6_-_136824277 43.869 Mgp
matrix Gla protein
chr17_-_57367499 42.904 C3
complement component 3
chr7_-_150646883 42.255 NM_001161624
NM_009876
 Cdkn1c

cyclin-dependent kinase inhibitor 1C (P57)

chr3_+_14863507 40.907 NM_007606
 Car3
carbonic anhydrase 3
chr7_-_110976438 40.385 Hbb-b1
hemoglobin, beta adult major chain

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 59 entries
Enrichment   P-value GO Accession GO Term
22.32 2.61e-02 GO:0006030 chitin metabolic process
22.32 2.61e-02 GO:0006032 chitin catabolic process
22.32 2.61e-02 GO:0044241 lipid digestion
16.74 1.30e-03 GO:0015669 gas transport
13.95 3.16e-02 GO:0045109 intermediate filament organization
12.18 1.08e-02 GO:0046470 phosphatidylcholine metabolic process
12.02 1.97e-03 GO:0031424 keratinization
12.02 1.97e-03 GO:0045103 intermediate filament-based process
10.72 2.42e-02 GO:0045104 intermediate filament cytoskeleton organization
9.92 7.27e-05 GO:0007586 digestion
8.68 2.06e-02 GO:0044236 multicellular organismal metabolic process
8.12 8.33e-03 GO:0007589 body fluid secretion
7.77 1.18e-02 GO:0042542 response to hydrogen peroxide
6.38 1.70e-02 GO:0043627 response to estrogen stimulus
6.28 1.94e-02 GO:0019748 secondary metabolic process
5.43 1.28e-03 GO:0006936 muscle contraction
5.23 1.31e-02 GO:0001890 placenta development
4.72 6.28e-03 GO:0003012 muscle system process
4.08 1.66e-03 GO:0010035 response to inorganic substance
4.03 3.52e-02 GO:0050878 regulation of body fluid levels

Gene overrepresentation in compartment category:

Showing 1 to 20 of 33 entries
Enrichment   P-value GO Accession GO Term
33.49 9.74e-03 GO:0031983 vesicle lumen
22.32 4.71e-02 GO:0031430 M band
11.16 8.59e-05 GO:0045095 keratin filament
8.37 1.49e-02 GO:0032994 protein-lipid complex
8.37 1.49e-02 GO:0034358 plasma lipoprotein particle
8.12 1.14e-03 GO:0032432 actin filament bundle
8.12 1.79e-02 GO:0005793 ER-Golgi intermediate compartment
7.77 1.62e-03 GO:0016528 sarcoplasm
7.77 1.62e-03 GO:0042641 actomyosin
7.62 6.92e-03 GO:0001725 stress fiber
7.44 8.15e-03 GO:0016529 sarcoplasmic reticulum
6.87 3.76e-04 GO:0031674 I band
6.62 5.53e-03 GO:0030018 Z disc
6.38 2.73e-06 GO:0044449 contractile fiber part
6.31 2.94e-05 GO:0030017 sarcomere
6.12 5.55e-07 GO:0043292 contractile fiber
5.88 8.51e-06 GO:0030016 myofibril
5.68 4.77e-02 GO:0016459 myosin complex
5.62 2.07e-06 GO:0005882 intermediate filament
5.12 5.65e-32 GO:0005615 extracellular space

Gene overrepresentation in function category:

Showing 1 to 17 of 17 entries
Enrichment   P-value GO Accession GO Term
23.39 5.50e-11 GO:0005212 structural constituent of eye lens
17.86 1.43e-02 GO:0015250 water channel activity
17.86 1.43e-02 GO:0019841 retinol binding
16.24 2.21e-02 GO:0005372 water transmembrane transporter activity
13.86 2.67e-06 GO:0005200 structural constituent of cytoskeleton
10.63 2.55e-02 GO:0001968 fibronectin binding
10.15 3.24e-02 GO:0005520 insulin-like growth factor binding
7.44 1.13e-02 GO:0043498 cell surface binding
6.60 2.33e-07 GO:0005179 hormone activity
5.32 4.29e-18 GO:0005198 structural molecule activity
4.44 1.07e-03 GO:0008083 growth factor activity
4.17 2.44e-05 GO:0005529 sugar binding
3.70 1.29e-07 GO:0030246 carbohydrate binding
3.47 1.72e-02 GO:0005125 cytokine activity
2.41 9.13e-07 GO:0005102 receptor binding
1.41 6.02e-05 GO:0005515 protein binding
1.18 1.27e-02 GO:0005488 binding