Motif ID: TCF4_dimer.p2

Z-value: 2.224


Transcription factors associated with TCF4_dimer.p2:

Gene SymbolEntrez IDGene Name
Tcf4 21413 transcription factor 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tcf4chr18_+_698435880.295.5e-05Click!


Activity profile for motif TCF4_dimer.p2.

activity profile for motif TCF4_dimer.p2


Sorted Z-values histogram for motif TCF4_dimer.p2

Sorted Z-values for motif TCF4_dimer.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TCF4_dimer.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_107806887 28.736 NM_001163183
NM_001163184
NM_001163185
Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr7_-_51780003 27.214 NM_146189
Mybpc2
myosin binding protein C, fast-type
chr15_+_81641832 27.027 NM_017376
Tef
thyrotroph embryonic factor
chr19_+_7131270 25.989 Macrod1
MACRO domain containing 1
chr15_+_81641869 25.880 Tef
thyrotroph embryonic factor
chr2_-_52194317 24.690 NM_010889
Neb
nebulin
chr7_-_30066642 24.230 Spint2
serine protease inhibitor, Kunitz type 2
chr19_+_7131234 23.909 NM_134147
Macrod1
MACRO domain containing 1
chr7_-_30066867 23.210 Spint2
serine protease inhibitor, Kunitz type 2
chr15_+_54402914 23.129 NM_178920
Mal2
mal, T-cell differentiation protein 2
chr7_-_30066910 22.104 NM_001082548
NM_011464
Spint2

serine protease inhibitor, Kunitz type 2

chr15_+_54402988 21.689 Mal2
mal, T-cell differentiation protein 2
chr3_-_126701367 21.618 NM_178655
Ank2
ankyrin 2, brain
chrX_+_162676903 21.529 Gpm6b
glycoprotein m6b
chrX_+_162676870 21.270 NM_001177961
NM_001177962
NM_023122
Gpm6b


glycoprotein m6b


chr19_+_20676453 20.860 NM_013467
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr4_+_84851330 19.271 NM_019535
Sh3gl2
SH3-domain GRB2-like 2
chr3_-_97571863 19.028 Pde4dip
phosphodiesterase 4D interacting protein (myomegalin)
chr15_+_99548011 18.977 Gpd1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr2_-_170232008 18.864 Bcas1
breast carcinoma amplified sequence 1
chr19_+_7131325 18.724 Macrod1
MACRO domain containing 1
chr6_+_48487648 18.653 Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
chr6_+_48487567 18.623 NM_133764
Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
chr18_+_82753560 18.284 Mbp
myelin basic protein
chr4_-_43536259 18.195 NM_009416
Tpm2
tropomyosin 2, beta
chr15_+_99548019 17.894 NM_010271
Gpd1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr16_-_31314534 17.775 NM_007470
Apod
apolipoprotein D
chr4_-_43536296 17.656 Tpm2
tropomyosin 2, beta
chr8_-_41720091 17.642 NM_001040699
Mtmr7
myotubularin related protein 7
chr7_+_149627709 17.453 Tnni2
troponin I, skeletal, fast 2
chr7_+_19876447 17.295 NM_001025364
Rtn2
reticulon 2 (Z-band associated protein)
chr9_+_69137694 17.019 Rora
RAR-related orphan receptor alpha
chr8_-_48374715 16.980 Stox2
storkhead box 2
chr16_+_91270319 16.660 Olig1
oligodendrocyte transcription factor 1
chr6_-_23789048 16.655 Cadps2
Ca2+-dependent activator protein for secretion 2
chr17_-_57226987 16.604 NM_009451
Tubb4
tubulin, beta 4
chr15_-_98637560 16.582 Ddn
dendrin
chr14_-_7859962 16.429 NM_001164727
Gm10406
predicted gene 10406
chr7_-_31912022 16.166 Scn1b
sodium channel, voltage-gated, type I, beta
chr1_+_179372452 15.462 Zfp238
zinc finger protein 238
chr7_+_149628285 15.413 NM_009405
Tnni2
troponin I, skeletal, fast 2
chr9_-_41932371 15.211 NM_011436
Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr9_-_41932195 14.974 Sorl1
sortilin-related receptor, LDLR class A repeats-containing
chr11_-_72303293 14.950 NM_153060
Spns2
spinster homolog 2 (Drosophila)
chr10_-_6979959 14.930 Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr16_+_6349108 14.887 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr9_+_69137659 14.831 Rora
RAR-related orphan receptor alpha
chr18_-_62071451 14.625 NM_198649
Ablim3
actin binding LIM protein family, member 3
chr11_+_82724754 14.598 NM_178680
Unc45b
unc-45 homolog B (C. elegans)
chr18_+_44493726 14.463 NM_001033621
Myot
myotilin
chr2_+_157387284 14.326 Nnat
neuronatin
chr4_-_133053867 14.305 Trnp1
TMF1-regulated nuclear protein 1
chr15_-_34608840 14.092 Nipal2
NIPA-like domain containing 2
chr15_+_34167908 13.939 Laptm4b
lysosomal-associated protein transmembrane 4B
chr18_+_45719732 13.921 NM_080465
Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr3_-_55987612 13.878 NM_030595
Nbea
neurobeachin
chr14_-_71035662 13.858 Epb4.9
erythrocyte protein band 4.9
chr19_+_25484006 13.850 Kank1
KN motif and ankyrin repeat domains 1
chr16_+_5885447 13.841 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr12_-_36769054 13.712 NM_025359
Tspan13
tetraspanin 13
chr3_-_97571843 13.525 Pde4dip
phosphodiesterase 4D interacting protein (myomegalin)
chr8_+_24249481 13.482 Ank1
ankyrin 1, erythroid
chr18_-_62071494 13.390 NM_001164491
Ablim3
actin binding LIM protein family, member 3
chr16_+_7069927 13.345 NM_183188
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr12_+_109572514 13.182 NM_010010
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr11_-_53293580 13.014 Ankrd43
ankyrin repeat domain 43
chr9_+_121686724 12.951 NM_028202
Kbtbd5
kelch repeat and BTB (POZ) domain containing 5
chr1_-_72921098 12.864 Igfbp5
insulin-like growth factor binding protein 5
chr15_+_97962651 12.840


chr4_+_95634005 12.797 NM_030014
Hook1
hook homolog 1 (Drosophila)
chr5_+_31418984 12.796 NM_021447
Trim54
tripartite motif-containing 54
chr16_+_7069971 12.788 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_+_31167731 12.717 Mapre3
microtubule-associated protein, RP/EB family, member 3
chr11_+_31900378 12.715 NM_008741
Nsg2
neuron specific gene family member 2
chr12_-_36768992 12.654 Tspan13
tetraspanin 13
chr3_+_90341208 12.628 S100a16
S100 calcium binding protein A16
chr4_+_42963222 12.545 Dnajb5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr8_-_113917651 12.531 NM_178086
Fa2h
fatty acid 2-hydroxylase
chr1_-_75215798 12.288 NM_009447
Tuba4a
tubulin, alpha 4A
chr17_+_43938905 12.262 Rcan2
regulator of calcineurin 2
chr11_-_53293696 12.200 NM_183173
Ankrd43
ankyrin repeat domain 43
chr10_+_19868725 12.198 NM_001198635
NM_008635
Mtap7

microtubule-associated protein 7

chr8_+_12915892 12.158 NM_178076
Mcf2l
mcf.2 transforming sequence-like
chr13_+_46513668 12.111 NM_001081425
Rbm24
RNA binding motif protein 24
chrX_+_98644445 12.049 NM_013712
Itgb1bp2
integrin beta 1 binding protein 2
chr14_-_55531726 11.998 NM_021551
Slc22a17
solute carrier family 22 (organic cation transporter), member 17
chr18_+_45719464 11.889 Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr14_-_56519012 11.849 NM_001082975
Sdr39u1
short chain dehydrogenase/reductase family 39U, member 1
chr15_-_98638230 11.816 Ddn
dendrin
chr4_+_84851029 11.815 Sh3gl2
SH3-domain GRB2-like 2
chr3_-_57651409 11.814 Pfn2
profilin 2
chr5_-_68238603 11.748 Atp8a1
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr8_+_86424565 11.707 Lphn1
latrophilin 1
chr11_-_69419330 11.653 Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr18_+_45719101 11.647 Kcnn2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr9_-_86775282 11.433 Snap91
synaptosomal-associated protein 91
chrX_+_98644459 11.366 Itgb1bp2
integrin beta 1 binding protein 2
chr9_-_35365985 11.326 NM_013932
Ddx25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr11_-_74424353 11.296 Rap1gap2
RAP1 GTPase activating protein 2
chr8_-_48374755 11.281 NM_001114311
Stox2
storkhead box 2
chr13_-_49243351 11.258 NM_029361
Wnk2
WNK lysine deficient protein kinase 2
chr9_-_121701480 11.194 NM_029095
Hhatl
hedgehog acyltransferase-like
chr3_+_108163704 11.159 Sort1
sortilin 1
chr3_-_57651621 11.092 NM_019410
Pfn2
profilin 2
chr15_-_76881097 11.018 NM_013593
Mb
myoglobin
chr16_+_18777032 10.999 Cldn5
claudin 5
chr17_+_43938887 10.977 Rcan2
regulator of calcineurin 2
chrX_-_56387565 10.962 NM_010200
Fgf13
fibroblast growth factor 13
chr16_-_45724720 10.878 Tagln3
transgelin 3
chr2_-_76820599 10.749 NM_011652
NM_028004
Ttn

titin

chr17_+_44090222 10.662 Rcan2
regulator of calcineurin 2
chr10_-_18463500 10.652 NM_001033258
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr6_-_23789259 10.635 NM_153163
Cadps2
Ca2+-dependent activator protein for secretion 2
chr8_+_121918768 10.627 NM_019966
Mlycd
malonyl-CoA decarboxylase
chr9_-_86775154 10.613 NM_013669
Snap91
synaptosomal-associated protein 91
chr11_+_68505416 10.582 NM_175260
Myh10
myosin, heavy polypeptide 10, non-muscle
chr1_-_79855229 10.522 NM_009255
Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr18_+_82754377 10.463 Mbp
myelin basic protein
chr19_-_45890238 10.436 NM_030716
NM_145703
NM_145704
Kcnip2


Kv channel-interacting protein 2


chr7_-_31230577 10.435 NM_007467
Aplp1
amyloid beta (A4) precursor-like protein 1
chr18_-_43059156 10.433 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr15_-_58046428 10.416 NM_026346
Fbxo32
F-box protein 32
chr4_-_154735351 10.395 NM_008860
Prkcz
protein kinase C, zeta
chr18_-_60783889 10.273 Synpo
synaptopodin
chr19_-_37281951 10.271 Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr17_+_44090139 10.265 NM_030598
Rcan2
regulator of calcineurin 2
chr1_-_79855177 10.250 Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr9_-_44607274 10.246 NM_027865
Tmem25
transmembrane protein 25
chr7_+_4071087 10.163 NM_001001454
NM_001109765
NM_021324
Ttyh1


tweety homolog 1 (Drosophila)


chr15_-_101543318 10.157 NM_027011
Krt5
keratin 5
chr1_+_137949360 10.088 NM_001081023
NM_014193
Cacna1s

calcium channel, voltage-dependent, L type, alpha 1S subunit

chr9_+_53109774 10.024 NM_176846
Exph5
exophilin 5
chr17_+_44090341 10.024 Rcan2
regulator of calcineurin 2
chr7_-_31230463 9.985 Aplp1
amyloid beta (A4) precursor-like protein 1
chr4_-_132848450 9.979


chr4_-_11313886 9.974 NM_194055
Esrp1
epithelial splicing regulatory protein 1
chr7_+_52955153 9.899 NM_009800
Car11
carbonic anhydrase 11
chr16_-_44333103 9.883 Sidt1
SID1 transmembrane family, member 1
chr4_-_133054355 9.881 NM_001081156
Trnp1
TMF1-regulated nuclear protein 1
chr1_-_79855209 9.865 Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr11_-_72303447 9.862 Spns2
spinster homolog 2 (Drosophila)
chr10_-_6979627 9.842 Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr3_-_108339375 9.840 NM_001033304
5330417C22Rik
RIKEN cDNA 5330417C22 gene
chr12_+_80130149 9.818 NM_181073
Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr3_+_14863507 9.800 NM_007606
Car3
carbonic anhydrase 3
chr1_-_72920776 9.789 Igfbp5
insulin-like growth factor binding protein 5
chr7_-_82453166 9.785 Sv2b
synaptic vesicle glycoprotein 2 b
chr17_-_26338106 9.742 Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr17_-_48571942 9.693 Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr17_+_43938789 9.690 NM_207649
Rcan2
regulator of calcineurin 2
chr18_-_33623400 9.634 NM_001109989
D0H4S114
DNA segment, human D4S114
chr4_-_151235861 9.580 NM_001081557
NM_001195565
Camta1

calmodulin binding transcription activator 1

chr11_+_68505616 9.563 Myh10
myosin, heavy polypeptide 10, non-muscle
chr5_-_52957466 9.551 Lgi2
leucine-rich repeat LGI family, member 2
chr12_+_91050912 9.488 Nrxn3
neurexin III
chrX_-_70905384 9.451 Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr7_+_137836057 9.444 NM_021314
Tacc2
transforming, acidic coiled-coil containing protein 2
chrX_-_70905062 9.344 NM_012040
Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr6_+_7505070 9.332 NM_009311
Tac1
tachykinin 1
chr13_+_97841524 9.331 NM_001100458
Fam169a
family with sequence similarity 169, member A
chr11_-_55223449 9.297 Sparc
secreted acidic cysteine rich glycoprotein
chr3_-_97628441 9.294 NM_001110163
Pde4dip
phosphodiesterase 4D interacting protein (myomegalin)
chr12_-_77811119 9.288 Spnb1
spectrin beta 1
chr7_-_112788821 9.271 NM_029802
Arfip2
ADP-ribosylation factor interacting protein 2
chr19_-_5349326 9.119 Cst6
cystatin E/M
chr16_-_28753276 9.117 NM_010199
Fgf12
fibroblast growth factor 12
chr18_+_25224729 9.077 Fhod3
formin homology 2 domain containing 3
chr7_+_137836116 9.057 Tacc2
transforming, acidic coiled-coil containing protein 2
chr9_+_110666191 9.046 Myl3
myosin, light polypeptide 3
chr18_-_33623287 8.999 NM_053078
D0H4S114
DNA segment, human D4S114
chr17_+_87153083 8.979 NM_010137
Epas1
endothelial PAS domain protein 1
chr11_+_101017307 8.967 Tubg2
tubulin, gamma 2
chr4_+_41774206 8.936 NM_011335
NM_001193668
NM_001193666
NM_023052
Ccl21b
Gm10591
Gm13304
Ccl21a
Ccl21c
chemokine (C-C motif) ligand 21B (leucine)
predicted gene 10591
predicted gene 13304
chemokine (C-C motif) ligand 21A (serine)
chemokine (C-C motif) ligand 21C (leucine)
chr1_+_75356906 8.935 Des
desmin
chr11_+_68505612 8.931 Myh10
myosin, heavy polypeptide 10, non-muscle
chr7_+_134094045 8.911 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr16_+_18776936 8.833 NM_013805
Cldn5
claudin 5
chr11_+_68901989 8.817 Vamp2
vesicle-associated membrane protein 2
chr16_-_45724422 8.776 NM_019754
Tagln3
transgelin 3
chr19_-_37281762 8.769 NM_198300
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr18_-_43058544 8.734 NM_027531
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr4_-_75779379 8.733 NM_001014288
Ptprd
protein tyrosine phosphatase, receptor type, D
chr15_-_78633301 8.719 NM_130859
Card10
caspase recruitment domain family, member 10
chr1_+_75356913 8.714 NM_010043
Des
desmin
chr14_+_70857227 8.697 NM_145981
Phyhip
phytanoyl-CoA hydroxylase interacting protein
chr18_+_61123204 8.692 NM_009792
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr17_-_48572043 8.669 NM_009694
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr15_+_97923019 8.655 NM_001163488
Pfkm
phosphofructokinase, muscle
chr19_-_5349573 8.628 NM_028623
Cst6
cystatin E/M
chr7_+_28856254 8.626 NM_001122603
Fcgbp
Fc fragment of IgG binding protein
chr16_+_18776955 8.609 Cldn5
claudin 5
chr9_+_110666178 8.571 NM_010859
Myl3
myosin, light polypeptide 3
chr16_+_43619057 8.565 Zbtb20
zinc finger and BTB domain containing 20
chr7_+_19996439 8.531 NM_007710
Ckm
creatine kinase, muscle
chr3_+_7366586 8.523 NM_008862
Pkia
protein kinase inhibitor, alpha
chr2_+_69508174 8.507 NM_001081087
Kbtbd10
kelch repeat and BTB (POZ) domain containing 10
chr13_-_92016479 8.491 NM_198415
Ckmt2
creatine kinase, mitochondrial 2
chr3_+_94928435 8.484 NM_016712
Tmod4
tropomodulin 4
chr7_+_133920438 8.476 NM_025347
NM_026875
Ypel3

yippee-like 3 (Drosophila)

chr1_-_66991580 8.462 Myl1
myosin, light polypeptide 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.29 6.03e-18 GO:0051179 localization
1.30 1.30e-15 GO:0006810 transport
1.30 3.67e-15 GO:0051234 establishment of localization
1.28 8.88e-14 GO:0048856 anatomical structure development
1.30 3.61e-13 GO:0048731 system development
1.25 6.78e-13 GO:0032502 developmental process
1.25 6.18e-12 GO:0007275 multicellular organismal development
1.40 1.86e-10 GO:0007399 nervous system development
1.27 1.77e-08 GO:0048869 cellular developmental process
1.27 2.39e-08 GO:0030154 cell differentiation
1.42 1.25e-07 GO:0048468 cell development
1.53 1.98e-07 GO:0030182 neuron differentiation
1.41 7.00e-07 GO:0006811 ion transport
1.58 7.25e-07 GO:0048666 neuron development
1.41 1.60e-06 GO:0048699 generation of neurons
1.47 2.45e-06 GO:0006812 cation transport
1.65 2.54e-06 GO:0032990 cell part morphogenesis
1.26 2.60e-06 GO:0065008 regulation of biological quality
1.66 2.74e-06 GO:0048858 cell projection morphogenesis
1.51 3.68e-06 GO:0030030 cell projection organization
1.39 4.61e-06 GO:0022008 neurogenesis
1.70 8.18e-06 GO:0048812 neuron projection morphogenesis
1.61 9.45e-06 GO:0031175 neuron projection development
1.29 1.18e-05 GO:0009653 anatomical structure morphogenesis
1.27 1.35e-05 GO:0051239 regulation of multicellular organismal process
1.53 2.73e-05 GO:0007267 cell-cell signaling
1.36 3.82e-05 GO:0051128 regulation of cellular component organization
1.58 4.38e-05 GO:0019226 transmission of nerve impulse
1.58 4.38e-05 GO:0035637 multicellular organismal signaling
1.41 4.56e-05 GO:0007154 cell communication
1.24 7.53e-05 GO:0048513 organ development
1.64 7.77e-05 GO:0007268 synaptic transmission
1.26 1.11e-04 GO:0023051 regulation of signaling
1.38 1.12e-04 GO:0055085 transmembrane transport
1.46 1.18e-04 GO:0030001 metal ion transport
1.51 1.38e-04 GO:0044057 regulation of system process
1.46 1.68e-04 GO:0032989 cellular component morphogenesis
1.64 2.77e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.82 3.04e-04 GO:0006813 potassium ion transport
1.67 3.60e-04 GO:0007409 axonogenesis
1.24 6.89e-04 GO:0065009 regulation of molecular function
2.64 7.13e-04 GO:0006941 striated muscle contraction
1.49 7.59e-04 GO:0007610 behavior
1.60 7.66e-04 GO:0061061 muscle structure development
1.23 9.49e-04 GO:0044281 small molecule metabolic process
1.87 9.60e-04 GO:0003012 muscle system process
1.46 1.43e-03 GO:0009719 response to endogenous stimulus
1.92 1.58e-03 GO:0006936 muscle contraction
1.44 1.68e-03 GO:0000902 cell morphogenesis
1.16 1.72e-03 GO:0016043 cellular component organization
1.53 1.87e-03 GO:0015672 monovalent inorganic cation transport
1.33 2.55e-03 GO:0051049 regulation of transport
1.28 2.69e-03 GO:0035556 intracellular signal transduction
1.27 3.98e-03 GO:0032879 regulation of localization
1.43 4.23e-03 GO:0006873 cellular ion homeostasis
1.42 4.70e-03 GO:0055082 cellular chemical homeostasis
1.36 5.00e-03 GO:0048878 chemical homeostasis
1.29 5.85e-03 GO:2000026 regulation of multicellular organismal development
1.68 6.51e-03 GO:0051493 regulation of cytoskeleton organization
1.25 6.68e-03 GO:0050790 regulation of catalytic activity
1.69 6.92e-03 GO:0007517 muscle organ development
1.18 8.83e-03 GO:0071842 cellular component organization at cellular level
1.26 9.17e-03 GO:0010646 regulation of cell communication
1.39 1.35e-02 GO:0050801 ion homeostasis
1.60 1.54e-02 GO:0031344 regulation of cell projection organization
1.36 1.64e-02 GO:0019725 cellular homeostasis
1.90 1.99e-02 GO:0006836 neurotransmitter transport
1.17 2.28e-02 GO:0048523 negative regulation of cellular process
1.15 2.36e-02 GO:0048522 positive regulation of cellular process
1.25 2.37e-02 GO:0050793 regulation of developmental process
1.23 2.91e-02 GO:0009966 regulation of signal transduction
1.55 3.81e-02 GO:0071495 cellular response to endogenous stimulus
1.62 3.84e-02 GO:0042391 regulation of membrane potential
1.15 4.52e-02 GO:0048519 negative regulation of biological process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.19 4.09e-31 GO:0005737 cytoplasm
1.12 2.05e-22 GO:0005622 intracellular
1.12 5.13e-21 GO:0044424 intracellular part
1.81 7.22e-19 GO:0045202 synapse
1.25 1.53e-16 GO:0071944 cell periphery
1.24 9.47e-16 GO:0005886 plasma membrane
1.19 1.32e-15 GO:0044444 cytoplasmic part
1.63 2.37e-13 GO:0043005 neuron projection
1.44 1.00e-12 GO:0042995 cell projection
1.79 4.44e-12 GO:0044456 synapse part
1.32 7.72e-12 GO:0044459 plasma membrane part
1.57 8.60e-12 GO:0030054 cell junction
1.10 9.81e-09 GO:0043229 intracellular organelle
1.09 1.57e-08 GO:0043226 organelle
1.39 3.26e-08 GO:0005626 insoluble fraction
1.74 6.69e-08 GO:0030424 axon
1.33 1.79e-07 GO:0000267 cell fraction
1.38 3.05e-07 GO:0005624 membrane fraction
1.56 3.60e-07 GO:0044463 cell projection part
2.47 5.98e-07 GO:0031674 I band
2.19 1.36e-06 GO:0030017 sarcomere
1.65 1.71e-06 GO:0030425 dendrite
1.60 2.63e-06 GO:0043025 neuronal cell body
2.02 4.97e-06 GO:0030016 myofibril
1.81 5.21e-06 GO:0034702 ion channel complex
1.27 5.72e-06 GO:0005856 cytoskeleton
1.96 9.02e-06 GO:0043292 contractile fiber
2.08 9.72e-06 GO:0008021 synaptic vesicle
1.04 1.27e-05 GO:0005623 cell
1.04 1.27e-05 GO:0044464 cell part
1.55 1.93e-05 GO:0044297 cell body
2.00 3.65e-05 GO:0044449 contractile fiber part
1.34 9.34e-05 GO:0031982 vesicle
1.35 1.22e-04 GO:0031410 cytoplasmic vesicle
2.36 1.30e-04 GO:0030018 Z disc
1.84 1.44e-04 GO:0033267 axon part
2.57 2.08e-04 GO:0042734 presynaptic membrane
1.97 2.66e-04 GO:0016327 apicolateral plasma membrane
1.58 8.22e-04 GO:0005911 cell-cell junction
1.93 1.05e-03 GO:0043296 apical junction complex
1.98 1.24e-03 GO:0005923 tight junction
1.98 1.24e-03 GO:0070160 occluding junction
1.72 1.51e-03 GO:0030136 clathrin-coated vesicle
1.86 1.63e-03 GO:0034703 cation channel complex
1.36 1.76e-03 GO:0031988 membrane-bounded vesicle
1.73 2.84e-03 GO:0019717 synaptosome
1.07 3.94e-03 GO:0043227 membrane-bounded organelle
1.98 4.47e-03 GO:0044309 neuron spine
1.35 4.51e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.64 4.52e-03 GO:0030135 coated vesicle
1.07 4.64e-03 GO:0043231 intracellular membrane-bounded organelle
1.48 4.75e-03 GO:0015629 actin cytoskeleton
1.22 5.18e-03 GO:0031090 organelle membrane
2.03 5.34e-03 GO:0008076 voltage-gated potassium channel complex
2.03 5.34e-03 GO:0034705 potassium channel complex
1.97 6.16e-03 GO:0043197 dendritic spine
2.52 8.37e-03 GO:0044304 main axon
1.43 1.02e-02 GO:0031012 extracellular matrix
1.25 1.02e-02 GO:0005794 Golgi apparatus
1.25 1.10e-02 GO:0044430 cytoskeletal part
1.17 1.38e-02 GO:0005576 extracellular region
1.41 4.28e-02 GO:0048471 perinuclear region of cytoplasm

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.20 3.14e-19 GO:0005515 protein binding
1.11 1.29e-17 GO:0005488 binding
1.66 3.98e-13 GO:0008092 cytoskeletal protein binding
1.38 8.39e-09 GO:0005215 transporter activity
2.18 9.96e-09 GO:0005516 calmodulin binding
1.42 1.05e-08 GO:0022857 transmembrane transporter activity
1.44 2.69e-08 GO:0022891 substrate-specific transmembrane transporter activity
1.46 5.47e-08 GO:0015075 ion transmembrane transporter activity
1.53 2.18e-07 GO:0008324 cation transmembrane transporter activity
1.38 3.05e-07 GO:0022892 substrate-specific transporter activity
1.48 3.57e-06 GO:0005509 calcium ion binding
1.62 5.43e-06 GO:0003779 actin binding
1.56 5.82e-06 GO:0005216 ion channel activity
1.54 7.55e-06 GO:0022803 passive transmembrane transporter activity
1.55 7.78e-06 GO:0022838 substrate-specific channel activity
1.53 1.18e-05 GO:0015267 channel activity
1.61 2.54e-05 GO:0022836 gated channel activity
1.74 1.02e-04 GO:0005244 voltage-gated ion channel activity
1.74 1.02e-04 GO:0022832 voltage-gated channel activity
1.61 1.63e-04 GO:0005261 cation channel activity
1.31 3.99e-04 GO:0030234 enzyme regulator activity
1.83 9.24e-04 GO:0005267 potassium channel activity
1.14 1.45e-03 GO:0046872 metal ion binding
1.13 2.08e-03 GO:0043169 cation binding
1.13 2.11e-03 GO:0043167 ion binding
2.25 2.33e-03 GO:0016247 channel regulator activity
1.76 3.07e-03 GO:0022843 voltage-gated cation channel activity
2.57 5.99e-03 GO:0035254 glutamate receptor binding
1.40 8.52e-03 GO:0008289 lipid binding
3.03 9.74e-03 GO:0015459 potassium channel regulator activity
1.40 1.21e-02 GO:0030695 GTPase regulator activity
1.39 1.51e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.26 1.77e-02 GO:0019899 enzyme binding
1.29 1.87e-02 GO:0046983 protein dimerization activity
1.83 2.69e-02 GO:0005249 voltage-gated potassium channel activity
1.47 3.58e-02 GO:0005083 small GTPase regulator activity