Motif ID: TFAP2B.p2

Z-value: 1.363


Transcription factors associated with TFAP2B.p2:

Gene SymbolEntrez IDGene Name
Tcfap2b 21419 transcription factor AP-2 beta

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tcfap2bchr1_+_19198994-0.366.0e-07Click!


Activity profile for motif TFAP2B.p2.

activity profile for motif TFAP2B.p2


Sorted Z-values histogram for motif TFAP2B.p2

Sorted Z-values for motif TFAP2B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP2B.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_28061156 32.911 NM_001038612
NM_019498
 Olfm1

olfactomedin 1

chr11_+_77306825 18.693 NM_001004144
 Git1
G protein-coupled receptor kinase-interactor 1
chr9_-_107134182 18.479 NM_153413
 Dock3
dedicator of cyto-kinesis 3
chr5_+_88994386 16.070 Rufy3
RUN and FYVE domain containing 3
chr8_-_126957835 14.783 NM_171824
 Pgbd5
piggyBac transposable element derived 5
chr19_-_5098486 14.215 Cnih2
cornichon homolog 2 (Drosophila)
chr6_+_117961386 13.672 Rasgef1a
RasGEF domain family, member 1A
chr4_+_129662284 13.625 NM_173071
 Bai2
brain-specific angiogenesis inhibitor 2
chr5_-_5380077 12.546 NM_011074
 Cdk14
cyclin-dependent kinase 14
chr1_-_134287712 12.354 NM_178874
 Tmcc2
transmembrane and coiled-coil domains 2
chr5_+_34339258 12.117 Nat8l
N-acetyltransferase 8-like
chr2_-_165060352 11.707 Cdh22
cadherin 22
chr14_-_13655558 11.518 Cadps
Ca2+-dependent secretion activator
chr17_+_69506165 11.033 Epb4.1l3
erythrocyte protein band 4.1-like 3
chr19_-_5098381 11.028 NM_009920
 Cnih2
cornichon homolog 2 (Drosophila)
chr1_+_63319842 10.913 NM_028673
 Zdbf2
zinc finger, DBF-type containing 2
chr10_-_115910578 10.865 NM_021452
 Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr5_+_34339351 10.674 Nat8l
N-acetyltransferase 8-like
chr16_-_18629938 10.670 NM_213614
 Sept5
septin 5
chr12_+_109792949 10.410 Evl
Ena-vasodilator stimulated phosphoprotein

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 219 entries
Enrichment   P-value GO Accession GO Term
2.75 4.81e-02 GO:0021766 hippocampus development
2.66 1.10e-02 GO:0050885 neuromuscular process controlling balance
2.63 2.90e-05 GO:0017157 regulation of exocytosis
2.59 1.80e-02 GO:0007269 neurotransmitter secretion
2.59 2.96e-02 GO:0045685 regulation of glial cell differentiation
2.41 1.18e-03 GO:0021543 pallium development
2.40 3.93e-02 GO:0014013 regulation of gliogenesis
2.38 8.89e-05 GO:0007018 microtubule-based movement
2.35 6.15e-06 GO:0031346 positive regulation of cell projection organization
2.24 3.80e-02 GO:0032886 regulation of microtubule-based process
2.19 2.96e-02 GO:0050905 neuromuscular process
2.15 2.61e-05 GO:0033124 regulation of GTP catabolic process
2.13 3.42e-04 GO:0050769 positive regulation of neurogenesis
2.12 5.71e-05 GO:0043087 regulation of GTPase activity
2.11 8.16e-03 GO:0006836 neurotransmitter transport
2.10 1.86e-08 GO:0031344 regulation of cell projection organization
2.10 6.64e-07 GO:0006605 protein targeting
2.05 3.47e-06 GO:0010975 regulation of neuron projection development
2.05 4.33e-02 GO:0050770 regulation of axonogenesis
2.04 5.23e-03 GO:0032318 regulation of Ras GTPase activity

Gene overrepresentation in compartment category:

Showing 1 to 20 of 90 entries
Enrichment   P-value GO Accession GO Term
3.11 4.27e-02 GO:0019005 SCF ubiquitin ligase complex
2.87 5.36e-04 GO:0043198 dendritic shaft
2.76 1.20e-02 GO:0008287 protein serine/threonine phosphatase complex
2.73 2.69e-03 GO:0000118 histone deacetylase complex
2.50 9.45e-04 GO:0030665 clathrin coated vesicle membrane
2.47 3.05e-02 GO:0042734 presynaptic membrane
2.42 4.15e-05 GO:0044309 neuron spine
2.42 6.75e-05 GO:0043197 dendritic spine
2.42 1.73e-02 GO:0005905 coated pit
2.35 3.26e-05 GO:0030427 site of polarized growth
2.26 1.63e-04 GO:0005802 trans-Golgi network
2.25 6.12e-08 GO:0019717 synaptosome
2.25 1.95e-05 GO:0008021 synaptic vesicle
2.24 4.22e-04 GO:0030426 growth cone
2.22 2.74e-17 GO:0030425 dendrite
2.22 3.18e-03 GO:0030662 coated vesicle membrane
2.19 8.48e-04 GO:0014069 postsynaptic density
2.18 1.35e-03 GO:0016585 chromatin remodeling complex
2.18 2.10e-02 GO:0030117 membrane coat
2.18 2.10e-02 GO:0048475 coated membrane

Gene overrepresentation in function category:

Showing 1 to 20 of 83 entries
Enrichment   P-value GO Accession GO Term
2.85 1.20e-02 GO:0019003 GDP binding
2.75 1.27e-02 GO:0015179 L-amino acid transmembrane transporter activity
2.59 4.68e-06 GO:0008565 protein transporter activity
2.59 7.85e-03 GO:0000149 SNARE binding
2.19 4.05e-06 GO:0005516 calmodulin binding
2.11 3.61e-09 GO:0019787 small conjugating protein ligase activity
2.10 6.24e-03 GO:0019887 protein kinase regulator activity
2.09 5.13e-05 GO:0051020 GTPase binding
2.09 1.80e-02 GO:0015081 sodium ion transmembrane transporter activity
2.08 4.20e-04 GO:0031267 small GTPase binding
2.07 8.49e-08 GO:0004842 ubiquitin-protein ligase activity
2.04 1.79e-02 GO:0005099 Ras GTPase activator activity
2.02 3.28e-10 GO:0005083 small GTPase regulator activity
2.02 5.66e-09 GO:0016881 acid-amino acid ligase activity
2.00 5.23e-03 GO:0017016 Ras GTPase binding
1.92 6.97e-14 GO:0060589 nucleoside-triphosphatase regulator activity
1.92 2.47e-04 GO:0003924 GTPase activity
1.91 3.46e-13 GO:0030695 GTPase regulator activity
1.91 2.48e-06 GO:0005096 GTPase activator activity
1.90 2.60e-03 GO:0022843 voltage-gated cation channel activity