Motif ID: TFAP4.p2

Z-value: 1.186


Transcription factors associated with TFAP4.p2:

Gene SymbolEntrez IDGene Name
Tcfap4 83383 transcription factor AP4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tcfap4chr16_-_4559511-0.163.2e-02Click!


Activity profile for motif TFAP4.p2.

activity profile for motif TFAP4.p2


Sorted Z-values histogram for motif TFAP4.p2

Sorted Z-values for motif TFAP4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_64820573 12.044 NM_001001488
Atp8b1
ATPase, class I, type 8B, member 1
chr7_-_30017388 11.676 NM_001033525
Kcnk6
potassium inwardly-rectifying channel, subfamily K, member 6
chr8_-_107995282 11.294 NM_026481
Tppp3
tubulin polymerization-promoting protein family member 3
chr8_-_107995252 10.779 Tppp3
tubulin polymerization-promoting protein family member 3
chr14_-_22806999 9.844 Zfp503
zinc finger protein 503
chr9_-_58160769 9.774 Loxl1
lysyl oxidase-like 1
chr10_-_76172218 9.529 Col6a1
collagen, type VI, alpha 1
chr4_+_104829963 9.494 Ppap2b
phosphatidic acid phosphatase type 2B
chr10_-_76576422 9.240 NM_001109991
Col18a1
collagen, type XVIII, alpha 1
chr4_+_104830022 9.065 Ppap2b
phosphatidic acid phosphatase type 2B
chr12_+_76409299 9.038 NM_023275
Rhoj
ras homolog gene family, member J
chr4_+_104829951 9.014 NM_080555
Ppap2b
phosphatidic acid phosphatase type 2B
chr3_+_90345082 8.954 NM_026416
S100a16
S100 calcium binding protein A16
chr11_-_32122236 8.661 Rhbdf1
rhomboid family 1 (Drosophila)
chr8_-_11312729 8.571 NM_009931
Col4a1
collagen, type IV, alpha 1
chr1_-_193141946 8.483 NM_025424
Nenf
neuron derived neurotrophic factor
chr7_+_80885223 8.090 Fam174b
family with sequence similarity 174, member B
chr4_+_104829867 8.016 Ppap2b
phosphatidic acid phosphatase type 2B
chr11_+_69778998 7.822 Cldn7
claudin 7
chr11_+_69778907 7.812 NM_016887
Cldn7
claudin 7
chr7_+_138079669 7.706 NM_019564
Htra1
HtrA serine peptidase 1
chr4_-_117963950 7.676 NM_011213
Ptprf
protein tyrosine phosphatase, receptor type, F
chr8_-_67171481 7.646 Cpe
carboxypeptidase E
chr19_-_24936327 7.543 NM_175013
Pgm5
phosphoglucomutase 5
chr8_-_11312686 7.404 Col4a1
collagen, type IV, alpha 1
chr10_-_94877824 7.345 NM_001168657
Socs2
suppressor of cytokine signaling 2
chr1_+_44608355 7.199 NM_028450
Gulp1
GULP, engulfment adaptor PTB domain containing 1
chr11_+_101192080 7.189 Aoc3
amine oxidase, copper containing 3
chr10_-_94878117 7.150 NM_001168656
Socs2
suppressor of cytokine signaling 2
chr2_-_26459777 6.900 Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr3_-_151929210 6.793 NM_199465
Nexn
nexilin
chr8_-_67171805 6.752 NM_013494
Cpe
carboxypeptidase E
chr2_+_35139479 6.688 Gsn
gelsolin
chr11_-_3427914 6.678 Smtn
smoothelin
chr6_+_4465627 6.565 Col1a2
collagen, type I, alpha 2
chr10_-_116719183 6.565 NM_017372
Lyz2
lysozyme 2
chr2_-_26459710 6.534 NM_026212
Agpat2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr6_+_56782073 6.519 Fkbp9
FK506 binding protein 9
chr1_-_195099209 6.423 G0s2
G0/G1 switch gene 2
chr10_-_116719364 6.409 Lyz2
lysozyme 2
chr7_+_35905996 6.396 Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr14_+_70009282 6.374 NM_033325
Loxl2
lysyl oxidase-like 2
chr11_+_61298923 6.356 NM_029568
Mfap4
microfibrillar-associated protein 4
chr14_-_22806631 6.352 Zfp503
zinc finger protein 503
chr6_+_43215604 6.170 NM_133674
Arhgef5
Rho guanine nucleotide exchange factor (GEF) 5
chr18_-_53577625 5.989 NM_008908
Ppic
peptidylprolyl isomerase C
chrX_-_109812258 5.926 NM_181579
Pof1b
premature ovarian failure 1B
chr2_+_155207542 5.869 Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr19_-_40588193 5.869 Sorbs1
sorbin and SH3 domain containing 1
chr9_-_58160063 5.766 Loxl1
lysyl oxidase-like 1
chr4_-_43536296 5.757 Tpm2
tropomyosin 2, beta
chr4_+_140976693 5.745 NM_013868
Hspb7
heat shock protein family, member 7 (cardiovascular)
chr2_-_165981138 5.732 NM_028072
Sulf2
sulfatase 2
chr2_+_32731648 5.700 NM_146119
Fam129b
family with sequence similarity 129, member B
chr3_+_104591946 5.689 NM_007484
Rhoc
ras homolog gene family, member C
chr13_+_56710896 5.656 NM_009369
Tgfbi
transforming growth factor, beta induced
chr9_+_50561315 5.596 Cryab
crystallin, alpha B
chr16_+_14705932 5.558 NM_011415
Snai2
snail homolog 2 (Drosophila)
chr19_-_40588235 5.505 Sorbs1
sorbin and SH3 domain containing 1
chr9_+_53192102 5.497 NM_212445
Kdelc2
KDEL (Lys-Asp-Glu-Leu) containing 2
chr2_-_165981085 5.465 Sulf2
sulfatase 2
chr10_-_116729893 5.440 NM_013590
Lyz1
lysozyme 1
chr11_-_7113899 5.430 NM_008343
Igfbp3
insulin-like growth factor binding protein 3
chr2_+_145611851 5.408 NM_028724
Rin2
Ras and Rab interactor 2
chr19_-_40588219 5.391 NM_178362
Sorbs1
sorbin and SH3 domain containing 1
chr15_-_58046380 5.374 Fbxo32
F-box protein 32
chr13_+_23776066 5.337 NM_023422
Hist1h2bc
histone cluster 1, H2bc
chr16_+_45094196 5.309 Ccdc80
coiled-coil domain containing 80
chr3_+_104591955 5.276 Rhoc
ras homolog gene family, member C
chr12_-_103057112 5.267 Fbln5
fibulin 5
chr8_-_64069935 5.236 Palld
palladin, cytoskeletal associated protein
chr11_-_68200284 5.212 NM_008744
Ntn1
netrin 1
chr14_+_34736772 5.212 NM_145741
Gdf10
growth differentiation factor 10
chr10_+_87322774 5.192 Igf1
insulin-like growth factor 1
chr18_+_20716598 5.160 NM_007883
Dsg2
desmoglein 2
chr13_-_23802696 5.153 Hfe
hemochromatosis
chr19_-_40588297 5.128 NM_009166
Sorbs1
sorbin and SH3 domain containing 1
chr8_-_42459932 5.100 NM_019734
Asah1
N-acylsphingosine amidohydrolase 1
chr18_+_60963495 5.083 NM_001042605
NM_010545
Cd74

CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

chr17_-_25218058 5.031 NM_001001183
Tmem204
transmembrane protein 204
chr7_-_26601526 4.998 NM_028775
Cyp2s1
cytochrome P450, family 2, subfamily s, polypeptide 1
chr9_+_50560862 4.924 NM_009964
Cryab
crystallin, alpha B
chr4_-_11313886 4.857 NM_194055
Esrp1
epithelial splicing regulatory protein 1
chr4_-_42393043 4.848 NM_011335
NM_001193668
NM_001193666
NM_023052
Ccl21b
Gm10591
Gm13304
Ccl21a
Ccl21c
chemokine (C-C motif) ligand 21B (leucine)
predicted gene 10591
predicted gene 13304
chemokine (C-C motif) ligand 21A (serine)
chemokine (C-C motif) ligand 21C (leucine)
chr14_+_34736806 4.764 Gdf10
growth differentiation factor 10
chr13_+_56711111 4.756 Tgfbi
transforming growth factor, beta induced
chr10_+_69707847 4.683 Slc16a9
solute carrier family 16 (monocarboxylic acid transporters), member 9
chr16_+_45094214 4.667 Ccdc80
coiled-coil domain containing 80
chr8_-_67171692 4.660 Cpe
carboxypeptidase E
chr7_-_139346304 4.654 Cpxm2
carboxypeptidase X 2 (M14 family)
chr15_+_34167780 4.642 NM_033521
Laptm4b
lysosomal-associated protein transmembrane 4B
chr9_+_50561121 4.628 Cryab
crystallin, alpha B
chr4_-_136448748 4.597 NM_007574
C1qc
complement component 1, q subcomponent, C chain
chr5_-_50450152 4.577 NM_133911
Gpr125
G protein-coupled receptor 125
chr8_-_75876420 4.525 NM_010687
Large
like-glycosyltransferase
chr2_+_102390226 4.481 Pamr1
peptidase domain containing associated with muscle regeneration 1
chr3_+_27837540 4.478 NM_001164056
Pld1
phospholipase D1
chr9_+_43942734 4.431 NM_023061
Mcam
melanoma cell adhesion molecule
chr2_+_33071451 4.411 NM_011923
Angptl2
angiopoietin-like 2
chr2_+_102390177 4.332 NM_173749
Pamr1
peptidase domain containing associated with muscle regeneration 1
chr7_-_149763600 4.322 H19
H19 fetal liver mRNA
chr10_+_79353597 4.306 NM_013459
Cfd
complement factor D (adipsin)
chr1_-_155179844 4.296 NM_010683
Lamc1
laminin, gamma 1
chr2_-_181406313 4.294 NM_009236
Sox18
SRY-box containing gene 18
chr6_-_125444695 4.259 Cd9
CD9 antigen
chr9_+_65478364 4.254 NM_028030
Rbpms2
RNA binding protein with multiple splicing 2
chr8_+_128519001 4.229 NM_008430
Kcnk1
potassium channel, subfamily K, member 1
chr4_-_43536259 4.221 NM_009416
Tpm2
tropomyosin 2, beta
chr1_+_91351435 4.215 Agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr7_+_3290587 4.213 Myadm
myeloid-associated differentiation marker
chr1_-_195099285 4.204 NM_008059
G0s2
G0/G1 switch gene 2
chr7_-_26588561 4.170 Cyp2s1
cytochrome P450, family 2, subfamily s, polypeptide 1
chr19_+_44368557 4.161 Scd2
stearoyl-Coenzyme A desaturase 2
chr7_-_135039020 4.160 NM_178600
Vkorc1
vitamin K epoxide reductase complex, subunit 1
chr15_-_76447278 4.135 NM_028064
Slc39a4
solute carrier family 39 (zinc transporter), member 4
chr8_-_94325138 4.126 NM_008393
Irx3
Iroquois related homeobox 3 (Drosophila)
chr7_-_20282950 4.082 Apoe
apolipoprotein E
chr17_-_57367499 4.067 C3
complement component 3
chr6_-_39068241 4.056 Parp12
poly (ADP-ribose) polymerase family, member 12
chr9_+_50561381 4.019 Cryab
crystallin, alpha B
chr7_-_148086285 3.987 Cox8b
cytochrome c oxidase, subunit VIIIb
chr7_+_29618812 3.982 NM_010706
Lgals4
Lgals6
lectin, galactose binding, soluble 4
lectin, galactose binding, soluble 6
chr9_+_23027519 3.922 NM_028472
Bmper
BMP-binding endothelial regulator
chr9_+_50561092 3.914 Cryab
crystallin, alpha B
chr19_+_44368578 3.890 Scd2
stearoyl-Coenzyme A desaturase 2
chr2_+_35122282 3.882 Gsn
gelsolin
chr11_+_76015590 3.877 Fam57a
family with sequence similarity 57, member A
chr12_-_103056971 3.858 Fbln5
fibulin 5
chr16_+_15887375 3.846 NM_007679
Cebpd
CCAAT/enhancer binding protein (C/EBP), delta
chr11_-_118216591 3.834 Timp2
tissue inhibitor of metalloproteinase 2
chr6_+_88674821 3.821 Mgll
monoglyceride lipase
chr6_-_39068340 3.821 NM_172893
Parp12
poly (ADP-ribose) polymerase family, member 12
chr19_+_44368576 3.729 Scd2
stearoyl-Coenzyme A desaturase 2
chr2_-_165980462 3.726 Sulf2
sulfatase 2
chr2_-_76511070 3.682 NM_010222
Fkbp7
FK506 binding protein 7
chr17_-_57367542 3.678 NM_009778
C3
complement component 3
chr19_+_38470458 3.666 NM_175507
Tmem20
transmembrane protein 20
chr7_+_148661329 3.665 Tspan4
tetraspanin 4
chr8_+_128519295 3.657 Kcnk1
potassium channel, subfamily K, member 1
chr5_+_35384200 3.653 NM_019447
Hgfac
hepatocyte growth factor activator
chr15_+_101242832 3.632 NM_033073
Krt7
keratin 7
chr7_+_3290516 3.613 NM_016969
NM_001093765
Myadm

myeloid-associated differentiation marker

chr2_-_13977502 3.583 Ptpla
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a
chr17_+_15080188 3.574 NM_001083880
NM_001083881
NM_001083882
NM_026451
1600012H06Rik



RIKEN cDNA 1600012H06 gene



chr16_+_45094383 3.567 Ccdc80
coiled-coil domain containing 80
chr18_+_58038278 3.563 NM_009194
Slc12a2
solute carrier family 12, member 2
chr10_-_27336648 3.559 NM_008481
Lama2
laminin, alpha 2
chr6_-_39067918 3.555 Parp12
poly (ADP-ribose) polymerase family, member 12
chr4_-_134828503 3.555 NM_013885
Clic4
chloride intracellular channel 4 (mitochondrial)
chr5_+_17080553 3.496 NM_013657
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr14_-_31981750 3.482 Stab1
stabilin 1
chr10_-_60610398 3.463 NM_009163
Sgpl1
sphingosine phosphate lyase 1
chr4_-_57155985 3.462 Epb4.1l4b
erythrocyte protein band 4.1-like 4b
chr1_+_91351373 3.457 NM_001037136
NM_178119
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chrX_+_165233030 3.456 NM_009707
Arhgap6
Rho GTPase activating protein 6
chr3_-_88351996 3.449 NM_016899
Rab25
RAB25, member RAS oncogene family
chr14_+_33669941 3.428 NM_178791
E130203B14Rik
RIKEN cDNA E130203B14 gene
chr8_+_28370796 3.414 NM_007918
Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
chr2_+_16277963 3.406 Plxdc2
plexin domain containing 2
chrX_-_147241307 3.400 Maged2
melanoma antigen, family D, 2
chr15_+_34236408 3.389 NM_016762
Matn2
matrilin 2
chr8_+_71404491 3.337 Lpl
lipoprotein lipase
chr1_-_51972718 3.332 Myo1b
myosin IB
chr16_+_93683426 3.300 NM_173047
Cbr3
carbonyl reductase 3
chr15_-_100467247 3.294 NM_174992
NM_001033872
Smagp

small cell adhesion glycoprotein

chr14_+_33670038 3.282 E130203B14Rik
RIKEN cDNA E130203B14 gene
chr7_-_28118628 3.279 NM_001113549
Ltbp4
latent transforming growth factor beta binding protein 4
chr4_-_136438225 3.276 C1qb
complement component 1, q subcomponent, beta polypeptide
chr13_-_3803547 3.275 NM_027416
Calml3
calmodulin-like 3
chr10_+_76721977 3.269 NM_030262
Pofut2
protein O-fucosyltransferase 2
chr18_+_12492494 3.268 NM_010680
Lama3
laminin, alpha 3
chr7_+_96552871 3.255 NM_008055
Fzd4
frizzled homolog 4 (Drosophila)
chr9_-_63868311 3.225 Smad6
MAD homolog 6 (Drosophila)
chr17_-_23877115 3.208 NM_023824
Paqr4
progestin and adipoQ receptor family member IV
chr7_-_118923483 3.201 NM_173739
Galntl4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4
chrX_-_137077133 3.179 Tsc22d3
TSC22 domain family, member 3
chr10_+_23943322 3.179 NM_021509
Moxd1
monooxygenase, DBH-like 1
chr7_-_133606617 3.171 Atp2a1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr2_-_104334599 3.166


chrX_+_147778717 3.134 NM_198105
Fam120c
family with sequence similarity 120, member C
chr1_-_52557130 3.123 NM_008667
Nab1
Ngfi-A binding protein 1
chr15_+_38908403 3.078 NM_026778
Cthrc1
collagen triple helix repeat containing 1
chr15_+_34167908 3.074 Laptm4b
lysosomal-associated protein transmembrane 4B
chr14_+_70008874 3.051 Loxl2
lysyl oxidase-like 2
chr17_+_29455821 3.044 NM_023734
Pi16
peptidase inhibitor 16
chr7_-_133606586 3.039 NM_007504
Atp2a1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr7_+_148661138 3.034 NM_053082
Tspan4
tetraspanin 4
chr11_-_3831515 3.022 Tcn2
transcobalamin 2
chr2_-_80421054 3.019 NM_016965
Nckap1
NCK-associated protein 1
chr9_-_58160966 3.018 NM_010729
Loxl1
lysyl oxidase-like 1
chr17_-_33918179 3.017 Angptl4
angiopoietin-like 4
chr17_-_28697643 3.005 NM_025469
Clps
colipase, pancreatic
chr19_-_36811090 3.001 NM_016854
Ppp1r3c
protein phosphatase 1, regulatory (inhibitor) subunit 3C
chrX_-_151650799 2.971 Sat1
spermidine/spermine N1-acetyl transferase 1
chr1_+_72871060 2.966 NM_008342
Igfbp2
insulin-like growth factor binding protein 2
chr7_+_96552955 2.959 Fzd4
frizzled homolog 4 (Drosophila)
chr10_+_115738429 2.952 NM_029928
Ptprb
protein tyrosine phosphatase, receptor type, B
chr9_-_108166059 2.945 NM_010017
Dag1
dystroglycan 1
chr2_-_6134008 2.936 NM_024208
Echdc3
enoyl Coenzyme A hydratase domain containing 3
chr10_+_12810593 2.935 NM_009538
Plagl1
pleiomorphic adenoma gene-like 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.69 3.09e-09 GO:0009966 regulation of signal transduction
1.54 7.65e-08 GO:0048583 regulation of response to stimulus
2.02 1.06e-07 GO:0072358 cardiovascular system development
2.02 1.06e-07 GO:0072359 circulatory system development
1.42 1.88e-07 GO:0048731 system development
1.67 1.89e-07 GO:0010646 regulation of cell communication
1.56 2.54e-07 GO:0023051 regulation of signaling
1.99 9.98e-07 GO:0005975 carbohydrate metabolic process
1.35 1.18e-06 GO:0007275 multicellular organismal development
1.36 1.57e-06 GO:0048518 positive regulation of biological process
2.11 1.64e-06 GO:0009968 negative regulation of signal transduction
1.33 1.85e-06 GO:0051179 localization
2.12 2.53e-06 GO:0044262 cellular carbohydrate metabolic process
1.32 3.96e-06 GO:0032502 developmental process
1.68 4.96e-06 GO:0009888 tissue development
1.36 7.01e-06 GO:0048856 anatomical structure development
1.40 1.02e-05 GO:0048523 negative regulation of cellular process
2.75 1.09e-05 GO:0019216 regulation of lipid metabolic process
1.98 1.80e-05 GO:0010648 negative regulation of cell communication
2.13 1.85e-05 GO:0001944 vasculature development
2.17 2.59e-05 GO:0001568 blood vessel development
1.96 3.67e-05 GO:0023057 negative regulation of signaling
1.35 4.07e-05 GO:0048522 positive regulation of cellular process
1.77 4.84e-05 GO:0022610 biological adhesion
1.45 5.30e-05 GO:0044281 small molecule metabolic process
1.17 5.91e-05 GO:0008152 metabolic process
1.77 6.28e-05 GO:0007155 cell adhesion
1.88 6.45e-05 GO:0009967 positive regulation of signal transduction
1.99 6.79e-05 GO:0010627 regulation of intracellular protein kinase cascade
1.67 8.85e-05 GO:0048584 positive regulation of response to stimulus
1.41 1.08e-04 GO:0065008 regulation of biological quality
1.84 1.29e-04 GO:0048585 negative regulation of response to stimulus
1.81 1.35e-04 GO:0023056 positive regulation of signaling
1.80 2.11e-04 GO:0010647 positive regulation of cell communication
1.32 2.19e-04 GO:0006810 transport
1.34 2.85e-04 GO:0048519 negative regulation of biological process
2.03 3.12e-04 GO:0051270 regulation of cellular component movement
2.08 3.66e-04 GO:0030334 regulation of cell migration
1.31 3.69e-04 GO:0051234 establishment of localization
1.40 3.86e-04 GO:0048513 organ development
2.62 5.88e-04 GO:0019318 hexose metabolic process
2.05 5.93e-04 GO:2000145 regulation of cell motility
1.60 7.95e-04 GO:0006629 lipid metabolic process
2.40 8.78e-04 GO:0005996 monosaccharide metabolic process
1.90 9.05e-04 GO:0006066 alcohol metabolic process
1.61 1.07e-03 GO:0055114 oxidation-reduction process
1.97 1.14e-03 GO:0040012 regulation of locomotion
1.57 1.17e-03 GO:2000026 regulation of multicellular organismal development
1.44 1.52e-03 GO:0009653 anatomical structure morphogenesis
3.31 1.62e-03 GO:0046890 regulation of lipid biosynthetic process
1.51 1.81e-03 GO:0050793 regulation of developmental process
2.02 2.88e-03 GO:0001501 skeletal system development
2.25 3.48e-03 GO:0009100 glycoprotein metabolic process
1.28 3.78e-03 GO:0019538 protein metabolic process
2.01 4.27e-03 GO:0031329 regulation of cellular catabolic process
2.06 5.10e-03 GO:0048514 blood vessel morphogenesis
2.03 5.27e-03 GO:0010740 positive regulation of intracellular protein kinase cascade
1.80 5.69e-03 GO:0060429 epithelium development
1.81 6.18e-03 GO:0045597 positive regulation of cell differentiation
1.35 7.87e-03 GO:0042221 response to chemical stimulus
3.18 1.08e-02 GO:0019217 regulation of fatty acid metabolic process
1.32 1.13e-02 GO:0048869 cellular developmental process
4.22 1.15e-02 GO:0046320 regulation of fatty acid oxidation
1.32 1.16e-02 GO:0030154 cell differentiation
1.43 1.20e-02 GO:0033036 macromolecule localization
1.70 1.53e-02 GO:0071310 cellular response to organic substance
3.50 1.61e-02 GO:0019218 regulation of steroid metabolic process
1.15 2.23e-02 GO:0044238 primary metabolic process
2.14 2.73e-02 GO:0051272 positive regulation of cellular component movement
2.45 2.80e-02 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.44 2.81e-02 GO:0010033 response to organic substance
1.78 2.98e-02 GO:0009725 response to hormone stimulus
2.49 3.10e-02 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
1.15 3.30e-02 GO:0044237 cellular metabolic process
4.87 3.39e-02 GO:0010812 negative regulation of cell-substrate adhesion
2.95 3.64e-02 GO:0034330 cell junction organization
1.20 3.90e-02 GO:0019222 regulation of metabolic process
1.63 3.96e-02 GO:0051094 positive regulation of developmental process
2.00 4.14e-02 GO:0001558 regulation of cell growth
1.44 4.19e-02 GO:0032879 regulation of localization
1.08 4.49e-02 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.35 2.27e-33 GO:0005737 cytoplasm
1.43 8.56e-27 GO:0044444 cytoplasmic part
1.22 2.82e-23 GO:0005622 intracellular
1.22 1.27e-21 GO:0044424 intracellular part
1.21 7.80e-14 GO:0043226 organelle
1.21 1.00e-13 GO:0043229 intracellular organelle
1.20 3.44e-10 GO:0043227 membrane-bounded organelle
1.20 4.04e-10 GO:0043231 intracellular membrane-bounded organelle
1.77 4.12e-10 GO:0044421 extracellular region part
1.09 1.22e-09 GO:0005623 cell
1.09 1.22e-09 GO:0044464 cell part
1.72 1.59e-09 GO:0005783 endoplasmic reticulum
2.44 4.87e-09 GO:0005773 vacuole
1.50 1.53e-08 GO:0005576 extracellular region
2.49 6.35e-08 GO:0000323 lytic vacuole
2.49 6.35e-08 GO:0005764 lysosome
2.34 6.57e-08 GO:0005578 proteinaceous extracellular matrix
1.60 1.19e-07 GO:0000267 cell fraction
2.22 1.25e-07 GO:0031012 extracellular matrix
1.54 2.71e-06 GO:0031090 organelle membrane
1.43 3.82e-06 GO:0044459 plasma membrane part
1.15 7.83e-06 GO:0016020 membrane
2.29 1.06e-05 GO:0005911 cell-cell junction
1.69 1.10e-05 GO:0005615 extracellular space
2.09 1.60e-05 GO:0044432 endoplasmic reticulum part
2.66 2.24e-05 GO:0070161 anchoring junction
2.74 2.45e-05 GO:0005912 adherens junction
1.56 5.91e-05 GO:0005794 Golgi apparatus
1.25 7.11e-05 GO:0005886 plasma membrane
1.55 1.14e-04 GO:0005626 insoluble fraction
1.24 1.49e-04 GO:0071944 cell periphery
2.08 1.49e-04 GO:0005789 endoplasmic reticulum membrane
2.18 1.73e-04 GO:0016323 basolateral plasma membrane
2.66 3.11e-04 GO:0044420 extracellular matrix part
1.65 3.17e-04 GO:0030054 cell junction
1.40 3.29e-04 GO:0005739 mitochondrion
3.04 3.36e-04 GO:0005604 basement membrane
2.06 4.40e-04 GO:0045177 apical part of cell
1.99 6.05e-04 GO:0042175 nuclear membrane-endoplasmic reticulum network
2.22 6.15e-04 GO:0016324 apical plasma membrane
1.51 1.15e-03 GO:0005624 membrane fraction
1.53 1.83e-03 GO:0012505 endomembrane system
2.65 6.82e-03 GO:0030055 cell-substrate junction
2.71 7.20e-03 GO:0005924 cell-substrate adherens junction
2.57 7.66e-03 GO:0016327 apicolateral plasma membrane
3.26 2.02e-02 GO:0005913 cell-cell adherens junction
2.58 3.76e-02 GO:0005925 focal adhesion
1.68 3.80e-02 GO:0005625 soluble fraction
1.12 4.17e-02 GO:0044425 membrane part
1.58 4.41e-02 GO:0009986 cell surface
1.75 4.91e-02 GO:0015629 actin cytoskeleton

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.35 5.97e-18 GO:0005515 protein binding
1.18 2.37e-14 GO:0005488 binding
1.24 1.03e-06 GO:0003824 catalytic activity
1.54 1.06e-04 GO:0005102 receptor binding
2.76 6.57e-04 GO:0019838 growth factor binding
1.88 7.10e-04 GO:0032403 protein complex binding
1.71 7.62e-04 GO:0019904 protein domain specific binding
1.69 1.60e-03 GO:0008092 cytoskeletal protein binding
1.78 4.57e-03 GO:0030246 carbohydrate binding
1.54 6.72e-03 GO:0016491 oxidoreductase activity
2.74 7.29e-03 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
7.14 3.40e-02 GO:0017166 vinculin binding
2.38 3.69e-02 GO:0016798 hydrolase activity, acting on glycosyl bonds
3.57 4.95e-02 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors