Motif ID: TFCP2.p2

Z-value: 2.914


Transcription factors associated with TFCP2.p2:

Gene SymbolEntrez IDGene Name
Tcfcp2 21422 transcription factor CP2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tcfcp2chr15_-_1003823540.321.2e-05Click!


Activity profile for motif TFCP2.p2.

activity profile for motif TFCP2.p2


Sorted Z-values histogram for motif TFCP2.p2

Sorted Z-values for motif TFCP2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFCP2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_81361077 59.218 Actn1
actinin, alpha 1
chr11_-_100275977 42.953 Leprel4
leprecan-like 4
chr11_-_100276112 40.888 NM_176830
 Leprel4
leprecan-like 4
chr7_-_106501584 39.556 Serpinh1
serine (or cysteine) peptidase inhibitor, clade H, member 1
chr7_-_106501642 37.564 NM_001111043
NM_001111044
NM_009825
 Serpinh1


serine (or cysteine) peptidase inhibitor, clade H, member 1


chr7_-_106501620 34.828 Serpinh1
serine (or cysteine) peptidase inhibitor, clade H, member 1
chr16_+_37777075 34.158 NM_008047
 Fstl1
follistatin-like 1
chr19_+_10116079 33.493 Fads3
fatty acid desaturase 3
chr12_-_81361302 30.501 NM_134156
 Actn1
actinin, alpha 1
chr1_-_82287990 29.805 NM_010570
 Irs1
insulin receptor substrate 1
chr11_+_29593657 28.983 NM_194051
 Rtn4
reticulon 4
chr16_-_85173851 28.736 App
amyloid beta (A4) precursor protein
chr4_-_55545211 28.536 Klf4
Kruppel-like factor 4 (gut)
chrX_-_49518428 28.421 Gpc4
glypican 4
chr9_-_58160063 28.036 Loxl1
lysyl oxidase-like 1
chr16_-_85173918 27.089 App
amyloid beta (A4) precursor protein
chr16_-_85173944 26.839 NM_001198823
NM_001198824
NM_001198825
NM_001198826
NM_007471
 App




amyloid beta (A4) precursor protein




chr3_+_104591946 26.597 NM_007484
 Rhoc
ras homolog gene family, member C
chr16_-_85173930 26.541 App
amyloid beta (A4) precursor protein
chr7_-_149763980 25.931 H19
H19 fetal liver mRNA

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 293 entries
Enrichment   P-value GO Accession GO Term
5.51 5.31e-03 GO:0061383 trabecula morphogenesis
5.29 2.96e-02 GO:0060343 trabecula formation
4.41 4.53e-03 GO:0010717 regulation of epithelial to mesenchymal transition
3.98 8.31e-03 GO:0070848 response to growth factor stimulus
3.78 8.15e-03 GO:0050673 epithelial cell proliferation
3.13 1.01e-04 GO:0048660 regulation of smooth muscle cell proliferation
3.07 9.83e-06 GO:0050679 positive regulation of epithelial cell proliferation
3.05 1.83e-02 GO:0001936 regulation of endothelial cell proliferation
2.94 4.71e-07 GO:0030198 extracellular matrix organization
2.94 3.90e-03 GO:0034330 cell junction organization
2.94 1.14e-02 GO:0043627 response to estrogen stimulus
2.88 3.28e-09 GO:0050678 regulation of epithelial cell proliferation
2.84 3.15e-10 GO:0001525 angiogenesis
2.76 2.15e-08 GO:0060537 muscle tissue development
2.74 7.43e-09 GO:0043062 extracellular structure organization
2.71 3.04e-03 GO:0051291 protein heterooligomerization
2.68 1.80e-06 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.68 1.80e-06 GO:0022604 regulation of cell morphogenesis
2.67 5.45e-15 GO:0001568 blood vessel development
2.67 1.74e-03 GO:0030879 mammary gland development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 81 entries
Enrichment   P-value GO Accession GO Term
6.62 2.46e-02 GO:0005915 zonula adherens
4.10 1.81e-03 GO:0009925 basal plasma membrane
3.63 4.34e-03 GO:0045178 basal part of cell
3.47 4.55e-09 GO:0030055 cell-substrate junction
3.40 6.47e-08 GO:0005924 cell-substrate adherens junction
3.35 3.76e-07 GO:0005925 focal adhesion
3.26 2.78e-03 GO:0005913 cell-cell adherens junction
3.26 2.78e-03 GO:0042641 actomyosin
3.23 1.14e-02 GO:0001725 stress fiber
3.21 6.66e-03 GO:0032432 actin filament bundle
3.01 3.25e-09 GO:0005912 adherens junction
2.94 6.40e-05 GO:0005604 basement membrane
2.82 2.45e-08 GO:0070161 anchoring junction
2.79 1.67e-06 GO:0044420 extracellular matrix part
2.55 3.28e-10 GO:0016323 basolateral plasma membrane
2.51 1.11e-02 GO:0030426 growth cone
2.48 2.70e-03 GO:0016327 apicolateral plasma membrane
2.42 2.10e-02 GO:0030427 site of polarized growth
2.40 1.41e-11 GO:0048471 perinuclear region of cytoplasm
2.39 1.17e-10 GO:0015629 actin cytoskeleton

Gene overrepresentation in function category:

Showing 1 to 20 of 41 entries
Enrichment   P-value GO Accession GO Term
5.88 7.61e-03 GO:0048407 platelet-derived growth factor binding
4.41 4.93e-02 GO:0031418 L-ascorbic acid binding
4.20 3.23e-02 GO:0001968 fibronectin binding
3.65 3.09e-02 GO:0005201 extracellular matrix structural constituent
2.94 3.95e-02 GO:0051219 phosphoprotein binding
2.86 6.19e-06 GO:0019838 growth factor binding
2.66 3.87e-02 GO:0005178 integrin binding
2.11 5.72e-13 GO:0008092 cytoskeletal protein binding
2.09 1.42e-07 GO:0005525 GTP binding
2.06 2.18e-06 GO:0003779 actin binding
2.04 2.57e-07 GO:0019001 guanyl nucleotide binding
2.04 2.57e-07 GO:0032561 guanyl ribonucleotide binding
2.03 1.25e-02 GO:0008022 protein C-terminus binding
2.00 1.71e-04 GO:0019901 protein kinase binding
1.91 1.57e-04 GO:0019900 kinase binding
1.87 1.05e-05 GO:0005198 structural molecule activity
1.87 1.17e-03 GO:0046982 protein heterodimerization activity
1.84 2.20e-07 GO:0019904 protein domain specific binding
1.79 1.73e-10 GO:0042802 identical protein binding
1.79 4.71e-04 GO:0032403 protein complex binding