Motif ID: TFDP1.p2

Z-value: 2.625


Transcription factors associated with TFDP1.p2:

Gene SymbolEntrez IDGene Name
Tfdp1 21781 transcription factor Dp 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tfdp1chr8_+_133387410.576.1e-17Click!


Activity profile for motif TFDP1.p2.

activity profile for motif TFDP1.p2


Sorted Z-values histogram for motif TFDP1.p2

Sorted Z-values for motif TFDP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFDP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_27693821 38.790 Hmga1
high mobility group AT-hook 1
chr6_-_47544925 28.650 NM_001146689
NM_007971
Ezh2

enhancer of zeste homolog 2 (Drosophila)

chr15_+_102236709 27.544 NM_013672
Sp1
trans-acting transcription factor 1
chr7_+_73254341 26.809 NM_001081163
Chsy1
chondroitin sulfate synthase 1
chr4_-_133309484 26.332 NM_001080819
Arid1a
AT rich interactive domain 1A (SWI-like)
chr17_+_31701700 26.208 NM_016670
Pknox1
Pbx/knotted 1 homeobox
chr10_+_43198945 25.569 NM_199028
Bend3
BEN domain containing 3
chr7_-_38892432 25.474 NM_007633
Ccne1
cyclin E1
chr16_-_22163035 24.610 Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr7_-_38892348 24.480 Ccne1
cyclin E1
chr17_+_27693518 24.382 NM_001166476
NM_001166477
NM_001025427
NM_001039356
NM_001166535
NM_001166536
NM_001166539
NM_001166540
NM_001166541
NM_001166542
NM_001166543
NM_001166544
NM_001166545
NM_001166546
NM_001166537
NM_016660
Hmga1-rs1

Hmga1













high mobility group AT-hook I, related sequence 1

high mobility group AT-hook 1













chr9_-_88376937 24.203 NM_019666
NM_019796
Syncrip

synaptotagmin binding, cytoplasmic RNA interacting protein

chr11_+_105043195 23.899 Tlk2
tousled-like kinase 2 (Arabidopsis)
chr5_+_65194814 23.150 Klf3
Kruppel-like factor 3 (basic)
chr11_-_106021399 23.088 NM_172397
Limd2
LIM domain containing 2
chr17_+_29627697 23.018 Pim1
proviral integration site 1
chr8_+_86521498 22.426 NM_001081415
Samd1
sterile alpha motif domain containing 1
chr11_-_102178559 21.811 NM_001044383
Ubtf
upstream binding transcription factor, RNA polymerase I
chr2_-_179711350 21.139 NM_001081092
Taf4a
TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr7_-_134169938 20.903 NM_010772
Maz
MYC-associated zinc finger protein (purine-binding transcription factor)
chr2_+_162880370 20.798 NM_008652
Mybl2
myeloblastosis oncogene-like 2
chr7_+_90015842 20.767 NM_175366
Mex3b
mex3 homolog B (C. elegans)
chr16_-_22163264 20.634 NM_183029
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr11_+_3190334 20.020 NM_019574
Patz1
POZ (BTB) and AT hook containing zinc finger 1
chr4_-_133443662 19.858 NM_009097
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr5_-_100407613 19.765 Hnrnpd
heterogeneous nuclear ribonucleoprotein D
chr11_-_106993235 19.569 NM_176850
Bptf
bromodomain PHD finger transcription factor
chr4_+_46463917 19.214 NM_130889
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr11_+_105043224 18.726 Tlk2
tousled-like kinase 2 (Arabidopsis)
chr7_+_16894925 18.717 NM_133234
Bbc3
BCL2 binding component 3
chr1_-_130256055 18.666 NM_008567
Mcm6
minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chr8_+_59990639 18.616 NM_008252
Hmgb2
high mobility group box 2
chr6_+_119429620 18.540 NM_133940
Fbxl14
F-box and leucine-rich repeat protein 14
chr5_-_96590773 18.336 NM_178854
Cnot6l
CCR4-NOT transcription complex, subunit 6-like
chr6_-_148894953 18.316 NM_019643
Fam60a
family with sequence similarity 60, member A
chr5_+_77694506 18.315 NM_011263
Rest
RE1-silencing transcription factor
chr15_-_82730215 17.938 Tbrg3
transforming growth factor beta regulated gene 3
chr11_-_102178941 17.923 Ubtf
upstream binding transcription factor, RNA polymerase I
chr1_-_167932735 17.896 NM_011137
NM_198932
Pou2f1

POU domain, class 2, transcription factor 1

chr3_+_137527448 17.818 NM_016750
H2afz
H2A histone family, member Z
chr9_-_24307580 17.667 NM_172920
Dpy19l1
dpy-19-like 1 (C. elegans)
chr10_+_53316720 17.546 NM_025541
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr17_-_35653683 17.456 NM_001163763
NM_001163764
NM_025674
Tcf19


transcription factor 19


chr7_+_26067559 17.418 Cic
capicua homolog (Drosophila)
chr15_+_102300972 17.389 NM_001103165
NM_001103166
NM_001174073
NM_011042
Pcbp2



poly(rC) binding protein 2



chr13_-_46823191 17.167 NM_175749
Nup153
nucleoporin 153
chr8_-_125075222 17.017 NM_001037298
Fam38a
family with sequence similarity 38, member A
chr12_+_110031520 16.988 NM_009537
Yy1
YY1 transcription factor
chr3_-_83844042 16.714 NM_172681
D930015E06Rik
RIKEN cDNA D930015E06 gene
chr9_+_56924152 16.698 NM_001110350
NM_011378
Sin3a

transcriptional regulator, SIN3A (yeast)

chr4_-_22415277 16.614 NM_008899
Pou3f2
POU domain, class 3, transcription factor 2
chr2_+_127161893 16.580 NM_010090
Dusp2
dual specificity phosphatase 2
chr8_+_107694536 16.501 NM_001161456
NM_001161457
NM_001161458
NM_022309
Cbfb



core binding factor beta



chr17_+_83750246 16.494 NM_001114361
NM_001114362
NM_199466
Eml4


echinoderm microtubule associated protein like 4


chr2_-_154395469 16.310 NM_007891
E2f1
E2F transcription factor 1
chr10_+_127669118 16.279 NM_001136082
NM_001164080
NM_001164081
Timeless


timeless homolog (Drosophila)


chr9_-_103267697 16.155 Cdv3
carnitine deficiency-associated gene expressed in ventricle 3
chrX_-_91368238 16.153 Zfx
zinc finger protein X-linked
chr17_+_29627950 16.070 NM_008842
Pim1
proviral integration site 1
chr16_-_8738377 15.930 NM_001003918
Usp7
ubiquitin specific peptidase 7
chr4_+_129190872 15.892 Marcksl1
MARCKS-like 1
chr18_-_6490848 15.886 NM_027497
Epc1
enhancer of polycomb homolog 1 (Drosophila)
chr13_+_55546643 15.692 NM_001038018
NM_001112711
NM_011938
Grk6


G protein-coupled receptor kinase 6


chr8_+_86479405 15.689 NM_024184
Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr12_+_110031153 15.650 Yy1
YY1 transcription factor
chr7_-_97129012 15.418 Eed
embryonic ectoderm development
chr9_+_100544186 15.369 Stag1
stromal antigen 1
chr4_+_129190877 15.245 Marcksl1
MARCKS-like 1
chr7_+_88138537 15.017 NM_178707
Zfp592
zinc finger protein 592
chr13_+_55546808 14.933 Grk6
G protein-coupled receptor kinase 6
chr7_+_26067197 14.900 NM_001110131
NM_001110132
NM_027882
Cic


capicua homolog (Drosophila)


chrX_-_139401258 14.862 NM_019496
Ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 homolog (human)
chr2_+_156665812 14.845 NM_173396
Tgif2
TGFB-induced factor homeobox 2
chr18_-_46685512 14.793 Fem1c
fem-1 homolog c (C.elegans)
chr13_+_35833181 14.723 NM_001123386
Cdyl
chromodomain protein, Y chromosome-like
chr5_+_65194784 14.610 Klf3
Kruppel-like factor 3 (basic)
chr11_-_95375552 14.535 Nxph3
neurexophilin 3
chr7_-_97129067 14.417 Eed
embryonic ectoderm development
chr7_-_97129450 14.373 NM_021876
Eed
embryonic ectoderm development
chr17_-_24388262 14.327 NM_007634
Ccnf
cyclin F
chr2_-_154394864 14.316 E2f1
E2F transcription factor 1
chr19_+_36484237 14.285 Pcgf5
polycomb group ring finger 5
chrX_-_91368427 14.272 Zfx
zinc finger protein X-linked
chr2_-_18919637 14.232 NM_008845
Pip4k2a
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr4_-_83132289 14.207 NM_133948
Psip1
PC4 and SFRS1 interacting protein 1
chrX_+_156065141 14.154 NM_001135727
Sh3kbp1
SH3-domain kinase binding protein 1
chr17_+_56443710 14.151 NM_001111078
NM_001111080
Uhrf1

ubiquitin-like, containing PHD and RING finger domains, 1

chr11_-_62462024 14.007 NM_198861
BC046404
cDNA sequence BC046404
chr5_-_144493077 13.941 NM_029749
Usp42
ubiquitin specific peptidase 42
chr17_+_56443766 13.882 Uhrf1
ubiquitin-like, containing PHD and RING finger domains, 1
chr18_+_56867378 13.754 NM_010721
Lmnb1
lamin B1
chr1_-_90598670 13.674 NM_177305
Arl4c
ADP-ribosylation factor-like 4C
chr14_-_32643594 13.648 NM_001024604
Ankrd28
ankyrin repeat domain 28
chr4_+_129190824 13.604 NM_010807
Marcksl1
MARCKS-like 1
chr5_-_96590868 13.565 NM_144910
Cnot6l
CCR4-NOT transcription complex, subunit 6-like
chr13_+_118009486 13.557 Emb
embigin
chr2_-_72817311 13.557 NM_001098425
Sp3
trans-acting transcription factor 3
chr11_-_97048933 13.541 Kpnb1
karyopherin (importin) beta 1
chr4_+_11118855 13.532 NM_009830
Ccne2
cyclin E2
chr11_-_51670897 13.530 NM_199299
Phf15
PHD finger protein 15
chr2_+_72314235 13.425 NM_025866
Cdca7
cell division cycle associated 7
chr6_+_29997972 13.418 NM_001164226
NM_001164227
NM_001164228
NM_001164230
NM_010938
Nrf1




nuclear respiratory factor 1




chr11_+_117710532 13.400 NM_001012273
NM_009689
Birc5

baculoviral IAP repeat-containing 5

chr13_-_69672716 13.394 NM_001169131
NM_198600
Papd7

PAP associated domain containing 7

chr5_-_138613028 13.390 NM_008568
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr14_-_31832165 13.380 Gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr2_-_154395076 13.274 E2f1
E2F transcription factor 1
chr14_-_52634206 13.232 Zfp219
zinc finger protein 219
chr8_-_124431581 13.196 NM_011404
Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr6_-_98978185 13.082 NM_001197322
Foxp1
forkhead box P1
chr19_+_47142217 13.058 NM_177342
Taf5
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr4_-_133189327 12.980 NM_001017968
Zdhhc18
zinc finger, DHHC domain containing 18
chr14_-_121778143 12.947 Stk24
serine/threonine kinase 24 (STE20 homolog, yeast)
chr8_+_13338741 12.920 Tfdp1
transcription factor Dp 1
chr5_+_125921949 12.863 Bri3bp
Bri3 binding protein
chr2_+_71227270 12.812 NM_026115
Hat1
histone aminotransferase 1
chr3_+_137527575 12.761 H2afz
H2A histone family, member Z
chr1_+_59970358 12.719 Fam117b
family with sequence similarity 117, member B
chr5_-_100468240 12.703 NM_016690
Hnrpdl
heterogeneous nuclear ribonucleoprotein D-like
chr13_-_21845695 12.680 NM_178183
Hist1h2ak
histone cluster 1, H2ak
chr3_+_30993952 12.675 NM_001039090
NM_011386
Skil

SKI-like

chr18_+_83080270 12.647 NM_183033
Zfp516
zinc finger protein 516
chr11_-_95375878 12.647 NM_130858
Nxph3
neurexophilin 3
chrX_+_20002875 12.641 Phf16
PHD finger protein 16
chr10_-_90634236 12.547 NM_001080129
NM_001080130
NM_001080131
NM_001080132
NM_001080134
NM_011605
Tmpo





thymopoietin





chr6_-_100237390 12.465 Rybp
RING1 and YY1 binding protein
chr11_+_97524725 12.286 NM_139311
Mllt6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr3_-_36470904 12.267 NM_009828
Ccna2
cyclin A2
chr12_+_77471173 12.255 NM_178744
Zbtb1
zinc finger and BTB domain containing 1
chr2_+_3630729 12.240 NM_025626
Fam107b
family with sequence similarity 107, member B
chr17_-_57170896 12.197 NM_010613
Khsrp
KH-type splicing regulatory protein
chr4_+_11118500 12.172 NM_001037134
Ccne2
cyclin E2
chr10_+_127669154 12.130 Timeless
timeless homolog (Drosophila)
chr13_-_48966134 12.047 Phf2
PHD finger protein 2
chr19_+_7049639 12.006 Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr11_-_102157904 11.958 NM_001098836
NM_001098837
Atxn7l3

ataxin 7-like 3

chr4_+_124334876 11.957 NM_011141
Pou3f1
POU domain, class 3, transcription factor 1
chr12_+_77471506 11.919 Zbtb1
zinc finger and BTB domain containing 1
chr2_+_29921953 11.868 Set
SET nuclear oncogene
chr11_-_115397455 11.860 NM_133354
Sumo2
SMT3 suppressor of mif two 3 homolog 2 (yeast)
chr16_+_94791713 11.822 NM_007890
Dyrk1a
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a
chr5_+_115879617 11.815 NM_008629
Msi1
Musashi homolog 1(Drosophila)
chr1_+_89749844 11.761 NM_177646
Dgkd
diacylglycerol kinase, delta
chr5_+_65194627 11.677 Klf3
Kruppel-like factor 3 (basic)
chr7_-_56136965 11.626 E2f8
E2F transcription factor 8
chr5_-_66089061 11.606 NM_001081321
Pds5a
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr18_+_75527015 11.591 NM_001042660
Smad7
MAD homolog 7 (Drosophila)
chr17_+_88840048 11.583 NM_180974
Foxn2
forkhead box N2
chr10_-_20880559 11.359 NM_001198914
NM_010848
Myb

myeloblastosis oncogene

chr2_-_152223710 11.358 NM_011438
Sox12
SRY-box containing gene 12
chr2_-_169956719 11.356 NM_001033299
Zfp217
zinc finger protein 217
chr10_-_116018526 11.310 NM_001037846
NM_001037847
NM_001037848
NM_028082
Cnot2



CCR4-NOT transcription complex, subunit 2



chr16_+_93832365 11.251 NM_001045529
Morc3
microrchidia 3
chr10_-_90545406 11.232 Apaf1
apoptotic peptidase activating factor 1
chr3_-_36470845 11.225 Ccna2
cyclin A2
chr17_-_26206487 11.206 Rab11fip3
RAB11 family interacting protein 3 (class II)
chr19_+_6085096 11.130 NM_026410
Cdca5
cell division cycle associated 5
chr1_+_168931547 11.102 NM_001160261
NM_001160262
NM_175461
Fam78b


family with sequence similarity 78, member B


chr19_-_4306221 11.017 Adrbk1
adrenergic receptor kinase, beta 1
chr10_+_40069255 10.985 Cdk19
cyclin-dependent kinase 19
chr15_-_77672472 10.967 NM_022410
Myh9
myosin, heavy polypeptide 9, non-muscle
chr11_+_69810424 10.956 Phf23
PHD finger protein 23
chr13_-_112599181 10.926 NM_011945
Map3k1
mitogen-activated protein kinase kinase kinase 1
chr2_-_162486634 10.921 Ptprt
protein tyrosine phosphatase, receptor type, T
chr1_+_43502790 10.877 Nck2
non-catalytic region of tyrosine kinase adaptor protein 2
chr14_-_121778399 10.847 NM_145465
Stk24
serine/threonine kinase 24 (STE20 homolog, yeast)
chr11_-_5344795 10.813 NM_001080924
Znrf3
zinc and ring finger 3
chr9_-_82868992 10.752 Phip
pleckstrin homology domain interacting protein
chr8_-_124431559 10.683 Slc7a5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr7_-_109398578 10.682 NM_019566
Rhog
ras homolog gene family, member G
chr2_+_146047656 10.662 NM_016889
Insm1
insulinoma-associated 1
chr10_-_126971614 10.654 NM_183297
Nxph4
neurexophilin 4
chr1_+_138521477 10.621 NM_001160251
NM_177643
Zfp281

zinc finger protein 281

chr18_-_67884185 10.601 NM_001127177
NM_008977
Ptpn2

protein tyrosine phosphatase, non-receptor type 2

chr7_-_26035683 10.597 NM_010155
Erf
Ets2 repressor factor
chr3_-_135354500 10.568 NM_008689
Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
chr13_-_99696254 10.543 NM_178716
Tnpo1
transportin 1
chr4_-_131817388 10.502 NM_001122992
NM_020273
Gmeb1

glucocorticoid modulatory element binding protein 1

chr15_-_36538484 10.430 Pabpc1
poly(A) binding protein, cytoplasmic 1
chr17_+_66132694 10.392 NM_001114131
NM_146081
Ppp4r1

protein phosphatase 4, regulatory subunit 1

chr6_-_91066809 10.387 NM_018815
Nup210
nucleoporin 210
chr4_-_154596628 10.370 NM_011385
Ski
ski sarcoma viral oncogene homolog (avian)
chr12_-_81361302 10.330 NM_134156
Actn1
actinin, alpha 1
chr11_+_69810948 10.315 Phf23
PHD finger protein 23
chr12_+_3806955 10.307 NM_007872
Dnmt3a
DNA methyltransferase 3A
chr19_+_7049425 10.306 NM_008889
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr11_-_96976562 10.263 NM_019507
Tbx21
T-box 21
chr17_-_32525894 10.242 NM_011717
Wiz
widely-interspaced zinc finger motifs
chr4_+_32702401 10.215 NM_001122978
NM_011997
Casp8ap2

caspase 8 associated protein 2

chr4_-_59562054 10.171 NM_144904
NM_178164
Rod1

ROD1 regulator of differentiation 1 (S. pombe)

chr11_+_118884275 10.166 NM_007623
Cbx2
chromobox homolog 2 (Drosophila Pc class)
chr17_-_48061354 10.162 Foxp4
forkhead box P4
chr19_+_36422888 10.145 Pcgf5
polycomb group ring finger 5
chr11_+_85124739 10.141 NM_016910
Ppm1d
protein phosphatase 1D magnesium-dependent, delta isoform
chr3_-_107135939 10.063 NM_001045807
Rbm15
RNA binding motif protein 15
chr17_-_32421603 10.040 Brd4
bromodomain containing 4
chr2_+_154617083 10.039 Raly
a
hnRNP-associated with lethal yellow
nonagouti
chr4_+_107474842 9.981 NM_001080926
Lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr1_-_54983211 9.980 NM_001081433
Ankrd44
ankyrin repeat domain 44
chr14_-_40286109 9.967 Nrg3
neuregulin 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.53 6.17e-110 GO:0044260 cellular macromolecule metabolic process
1.42 2.83e-103 GO:0044237 cellular metabolic process
1.61 2.17e-100 GO:0031323 regulation of cellular metabolic process
1.61 1.15e-98 GO:0080090 regulation of primary metabolic process
1.70 3.59e-94 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.69 1.84e-93 GO:0051171 regulation of nitrogen compound metabolic process
1.72 6.19e-93 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.54 9.03e-93 GO:0019222 regulation of metabolic process
1.46 1.42e-92 GO:0043170 macromolecule metabolic process
1.39 4.74e-92 GO:0044238 primary metabolic process
1.69 3.69e-91 GO:0010468 regulation of gene expression
1.59 9.30e-90 GO:0060255 regulation of macromolecule metabolic process
1.70 5.44e-89 GO:0010556 regulation of macromolecule biosynthetic process
1.73 3.29e-88 GO:0051252 regulation of RNA metabolic process
1.67 8.85e-87 GO:0031326 regulation of cellular biosynthetic process
1.73 2.43e-86 GO:0006355 regulation of transcription, DNA-dependent
1.66 2.19e-85 GO:0009889 regulation of biosynthetic process
1.33 3.57e-83 GO:0008152 metabolic process
1.57 6.56e-78 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.61 1.26e-72 GO:0090304 nucleic acid metabolic process
1.51 3.78e-71 GO:0034641 cellular nitrogen compound metabolic process
1.50 6.63e-70 GO:0006807 nitrogen compound metabolic process
1.64 4.79e-66 GO:0016070 RNA metabolic process
1.62 1.33e-65 GO:0034645 cellular macromolecule biosynthetic process
1.62 1.40e-65 GO:0009059 macromolecule biosynthetic process
1.75 2.83e-65 GO:0032774 RNA biosynthetic process
1.75 7.23e-65 GO:0006351 transcription, DNA-dependent
1.52 1.20e-61 GO:0044249 cellular biosynthetic process
1.51 3.20e-60 GO:0009058 biosynthetic process
1.57 3.12e-59 GO:0010467 gene expression
1.46 9.97e-52 GO:0032502 developmental process
1.47 5.01e-48 GO:0007275 multicellular organismal development
1.53 2.57e-47 GO:0048731 system development
1.49 6.66e-46 GO:0048856 anatomical structure development
1.45 2.07e-42 GO:0016043 cellular component organization
1.53 2.77e-41 GO:0071842 cellular component organization at cellular level
1.43 6.24e-40 GO:0071840 cellular component organization or biogenesis
1.14 1.08e-39 GO:0009987 cellular process
1.80 3.89e-39 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.50 7.35e-39 GO:0071841 cellular component organization or biogenesis at cellular level
1.50 2.09e-38 GO:0044267 cellular protein metabolic process
1.51 2.99e-38 GO:0048523 negative regulation of cellular process
1.59 3.15e-38 GO:0006464 protein modification process
1.52 1.87e-36 GO:0048869 cellular developmental process
1.56 2.30e-36 GO:0043412 macromolecule modification
1.52 2.89e-36 GO:0030154 cell differentiation
1.45 5.28e-36 GO:0048522 positive regulation of cellular process
1.47 5.60e-36 GO:0048519 negative regulation of biological process
1.42 2.70e-35 GO:0048518 positive regulation of biological process
1.53 1.81e-33 GO:0048513 organ development
1.73 1.98e-32 GO:0031324 negative regulation of cellular metabolic process
1.80 7.17e-32 GO:0009790 embryo development
1.65 1.24e-31 GO:0007399 nervous system development
1.82 2.08e-31 GO:0051254 positive regulation of RNA metabolic process
1.82 2.45e-31 GO:0045893 positive regulation of transcription, DNA-dependent
1.85 1.58e-30 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.61 1.79e-30 GO:0010604 positive regulation of macromolecule metabolic process
1.70 2.06e-30 GO:0010605 negative regulation of macromolecule metabolic process
1.77 2.56e-30 GO:0010628 positive regulation of gene expression
1.67 3.44e-30 GO:0009892 negative regulation of metabolic process
1.59 3.57e-30 GO:0009653 anatomical structure morphogenesis
1.57 1.00e-29 GO:0009893 positive regulation of metabolic process
1.59 1.09e-29 GO:0031325 positive regulation of cellular metabolic process
1.82 1.80e-29 GO:0010558 negative regulation of macromolecule biosynthetic process
1.80 1.81e-29 GO:0031327 negative regulation of cellular biosynthetic process
1.74 3.75e-29 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.56 8.55e-29 GO:0006996 organelle organization
1.72 9.49e-29 GO:0010557 positive regulation of macromolecule biosynthetic process
1.72 9.78e-29 GO:0051173 positive regulation of nitrogen compound metabolic process
1.83 9.97e-29 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.78 1.07e-28 GO:0009890 negative regulation of biosynthetic process
1.82 1.62e-28 GO:0051172 negative regulation of nitrogen compound metabolic process
1.68 2.48e-28 GO:0009891 positive regulation of biosynthetic process
1.69 2.49e-28 GO:0031328 positive regulation of cellular biosynthetic process
1.87 3.22e-28 GO:0051253 negative regulation of RNA metabolic process
1.87 7.28e-28 GO:0045892 negative regulation of transcription, DNA-dependent
1.96 1.77e-27 GO:0051276 chromosome organization
1.38 8.34e-27 GO:0019538 protein metabolic process
1.80 5.65e-26 GO:0010629 negative regulation of gene expression
2.08 9.48e-26 GO:0006325 chromatin organization
2.15 2.89e-25 GO:0016568 chromatin modification
1.89 3.47e-23 GO:0043009 chordate embryonic development
1.65 3.51e-23 GO:0009888 tissue development
1.88 5.79e-23 GO:0009792 embryo development ending in birth or egg hatching
1.67 3.44e-22 GO:0022008 neurogenesis
1.65 7.22e-22 GO:0048468 cell development
1.68 3.19e-21 GO:0048699 generation of neurons
1.78 1.47e-20 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.72 2.22e-19 GO:0009887 organ morphogenesis
1.55 4.89e-19 GO:0050793 regulation of developmental process
1.62 5.46e-19 GO:0007049 cell cycle
1.55 1.02e-18 GO:0006796 phosphate metabolic process
1.50 1.06e-18 GO:0009966 regulation of signal transduction
1.55 1.58e-18 GO:0006793 phosphorus metabolic process
1.96 1.27e-17 GO:0035295 tube development
1.90 1.71e-17 GO:0007389 pattern specification process
1.82 7.72e-17 GO:0048598 embryonic morphogenesis
1.58 1.10e-16 GO:0051128 regulation of cellular component organization
1.15 1.16e-16 GO:0050794 regulation of cellular process
1.43 1.16e-16 GO:0023051 regulation of signaling
1.83 4.65e-16 GO:0032583 regulation of gene-specific transcription
2.22 5.04e-16 GO:0016569 covalent chromatin modification
2.21 1.49e-15 GO:0016570 histone modification
1.14 2.00e-15 GO:0050789 regulation of biological process
1.79 3.99e-15 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.96 5.60e-15 GO:0018193 peptidyl-amino acid modification
1.53 1.06e-14 GO:2000026 regulation of multicellular organismal development
1.50 1.14e-14 GO:0032268 regulation of cellular protein metabolic process
1.56 1.42e-14 GO:0045595 regulation of cell differentiation
1.69 1.72e-14 GO:0030182 neuron differentiation
1.96 1.78e-14 GO:0001501 skeletal system development
1.98 2.22e-14 GO:0003002 regionalization
1.25 2.35e-14 GO:0051179 localization
1.13 2.82e-14 GO:0065007 biological regulation
1.86 3.57e-14 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.39 3.59e-14 GO:0065009 regulation of molecular function
1.93 4.86e-14 GO:0048568 embryonic organ development
1.52 3.43e-13 GO:0016310 phosphorylation
1.86 4.12e-13 GO:0070647 protein modification by small protein conjugation or removal
1.71 8.94e-13 GO:0007417 central nervous system development
2.21 1.75e-12 GO:0048705 skeletal system morphogenesis
1.65 2.10e-12 GO:0072358 cardiovascular system development
1.65 2.10e-12 GO:0072359 circulatory system development
1.67 2.86e-12 GO:0032989 cellular component morphogenesis
1.35 6.03e-12 GO:0048583 regulation of response to stimulus
1.69 1.07e-11 GO:0000902 cell morphogenesis
1.43 1.17e-11 GO:0035556 intracellular signal transduction
1.71 1.31e-11 GO:0060429 epithelium development
1.96 1.37e-11 GO:0035239 tube morphogenesis
1.43 1.49e-11 GO:0051246 regulation of protein metabolic process
1.47 1.50e-11 GO:0042127 regulation of cell proliferation
1.82 1.69e-11 GO:0001701 in utero embryonic development
1.67 1.86e-11 GO:0051726 regulation of cell cycle
1.43 3.75e-11 GO:0010941 regulation of cell death
1.63 3.79e-11 GO:0006259 DNA metabolic process
1.54 3.95e-11 GO:0033554 cellular response to stress
1.69 5.37e-11 GO:0048666 neuron development
1.74 5.64e-11 GO:0007167 enzyme linked receptor protein signaling pathway
1.42 6.26e-11 GO:0010646 regulation of cell communication
1.52 8.61e-11 GO:0006468 protein phosphorylation
1.43 1.41e-10 GO:0043067 regulation of programmed cell death
1.92 1.72e-10 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.43 2.03e-10 GO:0042981 regulation of apoptosis
1.60 2.37e-10 GO:0048646 anatomical structure formation involved in morphogenesis
1.70 3.35e-10 GO:0048729 tissue morphogenesis
1.86 5.69e-10 GO:0010608 posttranscriptional regulation of gene expression
1.67 5.99e-10 GO:0060284 regulation of cell development
1.73 6.72e-10 GO:0007420 brain development
1.80 7.01e-10 GO:0002009 morphogenesis of an epithelium
1.76 7.56e-10 GO:0032990 cell part morphogenesis
1.65 7.67e-10 GO:0010648 negative regulation of cell communication
1.38 8.42e-10 GO:0033036 macromolecule localization
1.76 9.70e-10 GO:0000904 cell morphogenesis involved in differentiation
1.66 1.02e-09 GO:0006974 response to DNA damage stimulus
1.48 1.13e-09 GO:0031399 regulation of protein modification process
1.65 1.29e-09 GO:0023057 negative regulation of signaling
2.12 1.67e-09 GO:0060541 respiratory system development
2.38 2.00e-09 GO:0048706 embryonic skeletal system development
1.68 2.26e-09 GO:0051960 regulation of nervous system development
1.67 2.27e-09 GO:0009968 negative regulation of signal transduction
1.81 2.50e-09 GO:0032446 protein modification by small protein conjugation
2.52 3.24e-09 GO:0006473 protein acetylation
2.40 3.26e-09 GO:0043543 protein acylation
1.76 3.77e-09 GO:0033043 regulation of organelle organization
1.99 4.06e-09 GO:0060562 epithelial tube morphogenesis
1.74 4.16e-09 GO:0048858 cell projection morphogenesis
1.72 4.62e-09 GO:0031175 neuron projection development
1.32 4.65e-09 GO:0051239 regulation of multicellular organismal process
1.58 5.21e-09 GO:0030030 cell projection organization
1.88 5.63e-09 GO:0030900 forebrain development
1.85 6.94e-09 GO:0043193 positive regulation of gene-specific transcription
1.94 7.21e-09 GO:0048562 embryonic organ morphogenesis
2.30 9.71e-09 GO:0018205 peptidyl-lysine modification
1.80 1.07e-08 GO:0048812 neuron projection morphogenesis
2.27 1.33e-08 GO:0030326 embryonic limb morphogenesis
2.27 1.33e-08 GO:0035113 embryonic appendage morphogenesis
1.70 1.40e-08 GO:0001944 vasculature development
1.35 1.66e-08 GO:0050790 regulation of catalytic activity
1.81 3.01e-08 GO:0016567 protein ubiquitination
1.38 4.77e-08 GO:0051641 cellular localization
1.38 5.58e-08 GO:0008104 protein localization
1.67 7.19e-08 GO:0050767 regulation of neurogenesis
1.74 7.86e-08 GO:0031329 regulation of cellular catabolic process
1.62 8.27e-08 GO:0000278 mitotic cell cycle
2.09 8.96e-08 GO:0030323 respiratory tube development
1.66 9.29e-08 GO:0051130 positive regulation of cellular component organization
1.67 9.37e-08 GO:0009894 regulation of catabolic process
2.51 1.02e-07 GO:0016573 histone acetylation
1.74 1.04e-07 GO:0006511 ubiquitin-dependent protein catabolic process
1.21 1.13e-07 GO:0051234 establishment of localization
2.09 1.19e-07 GO:0030324 lung development
1.66 1.21e-07 GO:0051301 cell division
1.88 1.50e-07 GO:0009952 anterior/posterior pattern formation
2.46 1.65e-07 GO:0018394 peptidyl-lysine acetylation
1.75 1.67e-07 GO:0061061 muscle structure development
1.69 2.04e-07 GO:0001568 blood vessel development
2.08 2.52e-07 GO:0048736 appendage development
2.08 2.52e-07 GO:0060173 limb development
2.51 3.20e-07 GO:0014031 mesenchymal cell development
1.21 3.28e-07 GO:0006810 transport
2.32 3.28e-07 GO:0060485 mesenchyme development
1.57 3.30e-07 GO:0022403 cell cycle phase
1.71 3.35e-07 GO:0007507 heart development
1.48 3.70e-07 GO:0022402 cell cycle process
2.44 4.09e-07 GO:0006475 internal protein amino acid acetylation
2.44 4.09e-07 GO:0018393 internal peptidyl-lysine acetylation
2.08 4.46e-07 GO:0035107 appendage morphogenesis
2.08 4.46e-07 GO:0035108 limb morphogenesis
1.87 5.07e-07 GO:0007346 regulation of mitotic cell cycle
1.70 5.81e-07 GO:0019941 modification-dependent protein catabolic process
2.39 6.22e-07 GO:0048704 embryonic skeletal system morphogenesis
1.50 6.92e-07 GO:0051094 positive regulation of developmental process
1.62 7.00e-07 GO:0022603 regulation of anatomical structure morphogenesis
2.34 7.08e-07 GO:0009953 dorsal/ventral pattern formation
1.41 7.62e-07 GO:0044093 positive regulation of molecular function
1.86 9.62e-07 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
2.88 9.65e-07 GO:0043966 histone H3 acetylation
1.69 1.00e-06 GO:0007264 small GTPase mediated signal transduction
1.69 1.01e-06 GO:0043632 modification-dependent macromolecule catabolic process
2.36 1.17e-06 GO:0048762 mesenchymal cell differentiation
1.51 1.22e-06 GO:0048585 negative regulation of response to stimulus
1.91 2.06e-06 GO:0001763 morphogenesis of a branching structure
1.76 2.32e-06 GO:0007409 axonogenesis
1.44 2.34e-06 GO:0042325 regulation of phosphorylation
1.43 2.37e-06 GO:0019220 regulation of phosphate metabolic process
1.43 2.37e-06 GO:0051174 regulation of phosphorus metabolic process
1.66 2.94e-06 GO:0051603 proteolysis involved in cellular protein catabolic process
1.79 3.42e-06 GO:0032582 negative regulation of gene-specific transcription
1.83 4.51e-06 GO:0007548 sex differentiation
1.89 5.30e-06 GO:0006260 DNA replication
1.62 5.83e-06 GO:0030163 protein catabolic process
1.58 6.05e-06 GO:0016071 mRNA metabolic process
2.06 6.21e-06 GO:0021915 neural tube development
1.64 8.18e-06 GO:0006281 DNA repair
1.70 8.30e-06 GO:0048514 blood vessel morphogenesis
1.63 1.05e-05 GO:0044257 cellular protein catabolic process
1.44 1.30e-05 GO:0001932 regulation of protein phosphorylation
1.60 1.51e-05 GO:0051098 regulation of binding
1.92 1.71e-05 GO:0061138 morphogenesis of a branching epithelium
1.58 1.83e-05 GO:0008283 cell proliferation
1.95 1.86e-05 GO:0043087 regulation of GTPase activity
1.59 1.87e-05 GO:0003006 developmental process involved in reproduction
2.04 2.30e-05 GO:0016331 morphogenesis of embryonic epithelium
1.56 2.48e-05 GO:0007423 sensory organ development
1.94 2.76e-05 GO:0033124 regulation of GTP catabolic process
1.52 2.96e-05 GO:0045597 positive regulation of cell differentiation
1.63 3.05e-05 GO:0045664 regulation of neuron differentiation
1.64 3.13e-05 GO:0051248 negative regulation of protein metabolic process
1.67 3.20e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.59 3.21e-05 GO:0045596 negative regulation of cell differentiation
1.94 3.68e-05 GO:0048754 branching morphogenesis of a tube
2.09 3.87e-05 GO:2000027 regulation of organ morphogenesis
1.70 4.07e-05 GO:0048732 gland development
1.50 4.33e-05 GO:0040008 regulation of growth
1.42 5.00e-05 GO:0040011 locomotion
1.79 5.20e-05 GO:0048608 reproductive structure development
1.40 5.24e-05 GO:0043085 positive regulation of catalytic activity
2.35 5.69e-05 GO:0060348 bone development
1.49 5.88e-05 GO:0051247 positive regulation of protein metabolic process
2.54 6.10e-05 GO:0060349 bone morphogenesis
1.99 6.24e-05 GO:0021537 telencephalon development
1.23 6.40e-05 GO:0065008 regulation of biological quality
1.78 9.09e-05 GO:0016055 Wnt receptor signaling pathway
2.10 9.11e-05 GO:0035148 tube formation
1.87 1.00e-04 GO:0010720 positive regulation of cell development
1.91 1.06e-04 GO:0008406 gonad development
1.51 1.06e-04 GO:0007610 behavior
1.79 1.16e-04 GO:0007517 muscle organ development
1.39 1.18e-04 GO:0007154 cell communication
1.49 1.36e-04 GO:0032270 positive regulation of cellular protein metabolic process
1.48 1.40e-04 GO:0044265 cellular macromolecule catabolic process
1.90 1.41e-04 GO:0007411 axon guidance
1.52 1.54e-04 GO:0008285 negative regulation of cell proliferation
1.34 1.62e-04 GO:0045184 establishment of protein localization
1.40 1.66e-04 GO:0046907 intracellular transport
1.47 1.71e-04 GO:0006928 cellular component movement
1.44 1.88e-04 GO:0009057 macromolecule catabolic process
1.62 1.89e-04 GO:0032269 negative regulation of cellular protein metabolic process
1.33 1.91e-04 GO:0051649 establishment of localization in cell
1.50 2.06e-04 GO:0016477 cell migration
1.82 2.26e-04 GO:0030811 regulation of nucleotide catabolic process
1.82 2.26e-04 GO:0033121 regulation of purine nucleotide catabolic process
1.82 2.26e-04 GO:0045137 development of primary sexual characteristics
1.33 2.38e-04 GO:0022607 cellular component assembly
2.56 2.39e-04 GO:0014033 neural crest cell differentiation
2.30 3.18e-04 GO:0014020 primary neural tube formation
1.95 3.35e-04 GO:0051216 cartilage development
2.09 3.44e-04 GO:0001838 embryonic epithelial tube formation
2.09 3.44e-04 GO:0072175 epithelial tube formation
1.58 3.53e-04 GO:0040007 growth
1.52 3.58e-04 GO:0007243 intracellular protein kinase cascade
1.52 3.58e-04 GO:0023014 signal transduction via phosphorylation event
2.38 3.76e-04 GO:0018105 peptidyl-serine phosphorylation
1.51 4.07e-04 GO:0002520 immune system development
1.61 4.08e-04 GO:0051101 regulation of DNA binding
1.54 4.96e-04 GO:0034621 cellular macromolecular complex subunit organization
1.81 5.28e-04 GO:0006417 regulation of translation
1.97 5.34e-04 GO:0051329 interphase of mitotic cell cycle
2.21 5.62e-04 GO:0018209 peptidyl-serine modification
1.65 5.83e-04 GO:0046578 regulation of Ras protein signal transduction
1.41 6.10e-04 GO:0010942 positive regulation of cell death
2.04 6.40e-04 GO:0040029 regulation of gene expression, epigenetic
2.79 6.61e-04 GO:0048701 embryonic cranial skeleton morphogenesis
1.60 6.68e-04 GO:0051056 regulation of small GTPase mediated signal transduction
1.57 7.11e-04 GO:0008380 RNA splicing
1.87 9.26e-04 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.73 9.29e-04 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
1.47 9.33e-04 GO:0051093 negative regulation of developmental process
1.33 9.39e-04 GO:0015031 protein transport
1.55 9.89e-04 GO:0006397 mRNA processing
1.36 1.04e-03 GO:0043933 macromolecular complex subunit organization
1.77 1.08e-03 GO:0048589 developmental growth
1.75 1.15e-03 GO:0001655 urogenital system development
1.45 1.35e-03 GO:0043549 regulation of kinase activity
1.44 1.46e-03 GO:0048870 cell motility
1.44 1.46e-03 GO:0051674 localization of cell
1.28 1.52e-03 GO:0044085 cellular component biogenesis
1.41 1.68e-03 GO:0060548 negative regulation of cell death
1.55 1.70e-03 GO:0034622 cellular macromolecular complex assembly
1.91 1.73e-03 GO:0051325 interphase
1.38 1.80e-03 GO:0071844 cellular component assembly at cellular level
2.52 1.98e-03 GO:0014032 neural crest cell development
1.54 2.10e-03 GO:0006140 regulation of nucleotide metabolic process
1.91 2.31e-03 GO:0043414 macromolecule methylation
1.85 2.34e-03 GO:0006470 protein dephosphorylation
2.88 2.34e-03 GO:0018210 peptidyl-threonine modification
1.78 2.34e-03 GO:0050890 cognition
1.37 2.36e-03 GO:0065003 macromolecular complex assembly
1.40 2.43e-03 GO:0043068 positive regulation of programmed cell death
1.60 2.59e-03 GO:0010564 regulation of cell cycle process
1.35 2.63e-03 GO:0012501 programmed cell death
1.38 2.70e-03 GO:0023056 positive regulation of signaling
1.46 2.70e-03 GO:0045859 regulation of protein kinase activity
1.68 2.90e-03 GO:0045165 cell fate commitment
1.38 2.98e-03 GO:0008284 positive regulation of cell proliferation
2.08 3.08e-03 GO:0006479 protein methylation
2.08 3.08e-03 GO:0008213 protein alkylation
2.12 3.41e-03 GO:0001892 embryonic placenta development
1.41 3.55e-03 GO:0043066 negative regulation of apoptosis
1.39 3.64e-03 GO:0043065 positive regulation of apoptosis
1.63 3.67e-03 GO:0033365 protein localization to organelle
1.35 3.69e-03 GO:0006915 apoptosis
1.93 3.76e-03 GO:0001890 placenta development
1.68 3.79e-03 GO:0051493 regulation of cytoskeleton organization
2.21 3.85e-03 GO:0001843 neural tube closure
1.33 3.87e-03 GO:0008219 cell death
1.33 3.95e-03 GO:0016265 death
1.39 4.21e-03 GO:0009967 positive regulation of signal transduction
1.59 4.22e-03 GO:0071900 regulation of protein serine/threonine kinase activity
1.47 4.29e-03 GO:0000279 M phase
1.60 4.30e-03 GO:0071495 cellular response to endogenous stimulus
1.61 4.45e-03 GO:0044087 regulation of cellular component biogenesis
1.89 4.48e-03 GO:0021953 central nervous system neuron differentiation
1.37 4.62e-03 GO:0010647 positive regulation of cell communication
1.44 5.17e-03 GO:0010627 regulation of intracellular protein kinase cascade
1.40 5.38e-03 GO:0043069 negative regulation of programmed cell death
1.56 5.92e-03 GO:0030029 actin filament-based process
1.62 6.00e-03 GO:0032870 cellular response to hormone stimulus
2.38 6.05e-03 GO:0061351 neural precursor cell proliferation
2.12 6.06e-03 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
2.12 6.06e-03 GO:0060070 canonical Wnt receptor signaling pathway
2.17 6.49e-03 GO:0060606 tube closure
1.57 6.53e-03 GO:0090046 regulation of transcription regulator activity
1.78 6.94e-03 GO:0003007 heart morphogenesis
1.77 7.18e-03 GO:0007611 learning or memory
1.95 8.14e-03 GO:0060538 skeletal muscle organ development
1.71 8.15e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.71 8.15e-03 GO:0022604 regulation of cell morphogenesis
1.87 8.60e-03 GO:0046777 protein autophosphorylation
2.31 8.60e-03 GO:0016571 histone methylation
1.99 8.64e-03 GO:0055123 digestive system development
2.05 8.67e-03 GO:0021543 pallium development
1.81 1.08e-02 GO:0001822 kidney development
1.80 1.13e-02 GO:0072001 renal system development
2.62 1.18e-02 GO:0060350 endochondral bone morphogenesis
1.20 1.20e-02 GO:0044281 small molecule metabolic process
1.45 1.24e-02 GO:0048534 hemopoietic or lymphoid organ development
1.83 1.30e-02 GO:0030534 adult behavior
1.40 1.30e-02 GO:0051338 regulation of transferase activity
1.62 1.37e-02 GO:0001525 angiogenesis
1.63 1.38e-02 GO:0016311 dephosphorylation
1.45 1.42e-02 GO:0031401 positive regulation of protein modification process
2.14 1.43e-02 GO:0042476 odontogenesis
1.81 1.44e-02 GO:0051100 negative regulation of binding
1.79 1.50e-02 GO:0050769 positive regulation of neurogenesis
2.20 1.51e-02 GO:0061008 hepaticobiliary system development
1.55 1.57e-02 GO:0000087 M phase of mitotic cell cycle
1.64 1.85e-02 GO:0060537 muscle tissue development
1.80 1.91e-02 GO:0032318 regulation of Ras GTPase activity
1.55 2.06e-02 GO:0000280 nuclear division
1.55 2.06e-02 GO:0007067 mitosis
2.00 2.07e-02 GO:0001841 neural tube formation
1.92 2.15e-02 GO:0007519 skeletal muscle tissue development
1.85 2.17e-02 GO:0009791 post-embryonic development
1.39 2.27e-02 GO:0009719 response to endogenous stimulus
1.73 2.29e-02 GO:0010638 positive regulation of organelle organization
3.20 2.30e-02 GO:0042481 regulation of odontogenesis
1.97 2.34e-02 GO:0007612 learning
1.80 2.53e-02 GO:0071375 cellular response to peptide hormone stimulus
1.77 2.73e-02 GO:0030278 regulation of ossification
2.07 2.77e-02 GO:0001657 ureteric bud development
1.64 3.14e-02 GO:0050678 regulation of epithelial cell proliferation
2.58 3.14e-02 GO:0001837 epithelial to mesenchymal transition
1.70 3.14e-02 GO:0043583 ear development
1.54 3.25e-02 GO:0030036 actin cytoskeleton organization
1.54 3.35e-02 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity
2.16 3.37e-02 GO:0001889 liver development
1.88 3.39e-02 GO:0043392 negative regulation of DNA binding
1.52 3.62e-02 GO:0048285 organelle fission
1.44 3.67e-02 GO:0040012 regulation of locomotion
1.73 3.90e-02 GO:0032259 methylation
2.43 4.04e-02 GO:0035137 hindlimb morphogenesis
1.64 4.11e-02 GO:0042692 muscle cell differentiation
3.58 4.76e-02 GO:0071897 DNA biosynthetic process
1.60 4.86e-02 GO:0010975 regulation of neuron projection development
1.60 4.86e-02 GO:0042391 regulation of membrane potential

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.33 5.64e-179 GO:0005622 intracellular
1.33 2.29e-173 GO:0044424 intracellular part
1.37 7.68e-152 GO:0043226 organelle
1.37 6.62e-151 GO:0043229 intracellular organelle
1.39 4.96e-144 GO:0043227 membrane-bounded organelle
1.39 4.90e-143 GO:0043231 intracellular membrane-bounded organelle
1.56 1.90e-134 GO:0005634 nucleus
1.29 1.91e-73 GO:0005737 cytoplasm
1.13 1.08e-64 GO:0005623 cell
1.13 1.08e-64 GO:0044464 cell part
1.44 2.48e-64 GO:0044446 intracellular organelle part
1.43 8.38e-63 GO:0044422 organelle part
1.69 1.03e-57 GO:0044428 nuclear part
1.74 1.25e-52 GO:0031981 nuclear lumen
1.66 1.82e-51 GO:0031974 membrane-enclosed lumen
1.67 2.18e-51 GO:0043233 organelle lumen
1.67 2.21e-51 GO:0070013 intracellular organelle lumen
1.85 1.04e-46 GO:0005654 nucleoplasm
1.44 1.09e-39 GO:0043234 protein complex
1.38 1.98e-37 GO:0032991 macromolecular complex
1.88 4.43e-33 GO:0044451 nucleoplasm part
1.24 3.06e-27 GO:0044444 cytoplasmic part
1.36 4.64e-22 GO:0043228 non-membrane-bounded organelle
1.36 4.64e-22 GO:0043232 intracellular non-membrane-bounded organelle
1.73 5.92e-15 GO:0005694 chromosome
1.76 8.33e-15 GO:0044427 chromosomal part
1.38 5.59e-14 GO:0005829 cytosol
2.62 4.49e-12 GO:0016585 chromatin remodeling complex
1.78 2.29e-11 GO:0005667 transcription factor complex
1.94 7.46e-11 GO:0000228 nuclear chromosome
1.93 8.26e-11 GO:0000785 chromatin
2.00 1.16e-10 GO:0044454 nuclear chromosome part
1.33 1.72e-10 GO:0005856 cytoskeleton
2.27 9.40e-09 GO:0000790 nuclear chromatin
1.35 1.66e-08 GO:0042995 cell projection
1.49 3.51e-08 GO:0015630 microtubule cytoskeleton
1.37 3.82e-08 GO:0005794 Golgi apparatus
1.37 1.32e-07 GO:0044430 cytoskeletal part
2.50 1.40e-07 GO:0000792 heterochromatin
1.46 3.00e-07 GO:0043005 neuron projection
2.65 1.78e-06 GO:0017053 transcriptional repressor complex
1.47 2.90e-06 GO:0045202 synapse
2.40 5.37e-06 GO:0034708 methyltransferase complex
2.40 5.37e-06 GO:0035097 histone methyltransferase complex
2.34 6.09e-06 GO:0000123 histone acetyltransferase complex
2.69 2.15e-05 GO:0005720 nuclear heterochromatin
1.51 2.26e-05 GO:0005730 nucleolus
1.33 4.07e-05 GO:0012505 endomembrane system
1.36 1.30e-04 GO:0030054 cell junction
1.78 1.85e-04 GO:0016604 nuclear body
1.44 1.93e-04 GO:0044463 cell projection part
1.35 2.25e-04 GO:0031975 envelope
1.35 2.63e-04 GO:0031967 organelle envelope
1.53 3.25e-04 GO:0015629 actin cytoskeleton
2.33 3.86e-04 GO:0016363 nuclear matrix
2.49 6.98e-04 GO:0000118 histone deacetylase complex
1.53 7.80e-04 GO:0030424 axon
1.52 9.27e-04 GO:0005874 microtubule
2.58 1.34e-03 GO:0008287 protein serine/threonine phosphatase complex
2.10 2.41e-03 GO:0034399 nuclear periphery
1.48 2.47e-03 GO:0030425 dendrite
1.57 2.68e-03 GO:0005813 centrosome
1.22 2.84e-03 GO:0031090 organelle membrane
1.42 2.93e-03 GO:0005625 soluble fraction
2.86 3.02e-03 GO:0000803 sex chromosome
1.53 4.35e-03 GO:0005815 microtubule organizing center
1.46 5.10e-03 GO:0044431 Golgi apparatus part
1.19 7.15e-03 GO:0005739 mitochondrion
1.41 8.69e-03 GO:0044297 cell body
2.81 8.73e-03 GO:0001739 sex chromatin
1.42 9.39e-03 GO:0043025 neuronal cell body
2.90 9.73e-03 GO:0031519 PcG protein complex
1.68 9.83e-03 GO:0005912 adherens junction
1.71 1.65e-02 GO:0005819 spindle
1.21 1.66e-02 GO:0000267 cell fraction
1.62 2.10e-02 GO:0070161 anchoring junction
2.76 2.48e-02 GO:0019005 SCF ubiquitin ligase complex
1.80 3.13e-02 GO:0014069 postsynaptic density
2.34 3.33e-02 GO:0005657 replication fork
1.78 4.33e-02 GO:0030427 site of polarized growth
1.60 4.55e-02 GO:0000775 chromosome, centromeric region

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.26 1.19e-103 GO:0005488 binding
1.35 7.72e-63 GO:0005515 protein binding
1.56 6.03e-59 GO:0003676 nucleic acid binding
1.66 2.31e-52 GO:0003677 DNA binding
1.81 3.81e-38 GO:0030528 transcription regulator activity
1.85 6.62e-30 GO:0043565 sequence-specific DNA binding
1.79 1.12e-29 GO:0001071 nucleic acid binding transcription factor activity
1.79 1.12e-29 GO:0003700 sequence-specific DNA binding transcription factor activity
1.43 5.92e-28 GO:0000166 nucleotide binding
1.50 2.13e-22 GO:0008270 zinc ion binding
2.25 7.03e-19 GO:0003682 chromatin binding
1.20 3.36e-17 GO:0003824 catalytic activity
1.38 5.14e-17 GO:0016740 transferase activity
1.94 1.58e-16 GO:0008134 transcription factor binding
1.37 3.51e-16 GO:0035639 purine ribonucleoside triphosphate binding
1.36 4.09e-16 GO:0032553 ribonucleotide binding
1.38 4.68e-16 GO:0046914 transition metal ion binding
1.55 4.70e-16 GO:0019899 enzyme binding
1.36 5.79e-16 GO:0032555 purine ribonucleotide binding
1.36 5.96e-16 GO:0017076 purine nucleotide binding
1.24 3.44e-15 GO:0043169 cation binding
1.24 3.90e-15 GO:0043167 ion binding
1.24 4.05e-15 GO:0046872 metal ion binding
1.67 1.66e-14 GO:0019904 protein domain specific binding
1.85 1.68e-14 GO:0016563 transcription activator activity
1.49 2.98e-14 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.84 3.10e-13 GO:0016564 transcription repressor activity
1.95 6.74e-13 GO:0000988 protein binding transcription factor activity
1.94 1.78e-12 GO:0000989 transcription factor binding transcription factor activity
1.94 3.52e-12 GO:0003712 transcription cofactor activity
1.48 1.32e-11 GO:0016301 kinase activity
1.53 1.37e-11 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.34 6.80e-11 GO:0032559 adenyl ribonucleotide binding
1.34 6.95e-11 GO:0030554 adenyl nucleotide binding
1.34 9.30e-11 GO:0005524 ATP binding
1.65 2.49e-10 GO:0004674 protein serine/threonine kinase activity
1.76 3.19e-10 GO:0019900 kinase binding
1.54 6.24e-10 GO:0004672 protein kinase activity
1.80 2.01e-09 GO:0019901 protein kinase binding
1.87 3.31e-09 GO:0000975 regulatory region DNA binding
1.87 3.31e-09 GO:0001067 regulatory region nucleic acid binding
1.87 3.31e-09 GO:0044212 transcription regulatory region DNA binding
1.43 6.12e-09 GO:0042802 identical protein binding
1.86 3.49e-08 GO:0010843 promoter binding
1.58 7.59e-08 GO:0016874 ligase activity
1.77 2.52e-07 GO:0016881 acid-amino acid ligase activity
2.20 4.52e-07 GO:0003714 transcription corepressor activity
1.80 6.18e-07 GO:0019787 small conjugating protein ligase activity
1.78 1.17e-06 GO:0043566 structure-specific DNA binding
1.94 1.22e-06 GO:0003713 transcription coactivator activity
2.31 1.27e-06 GO:0042393 histone binding
1.40 1.37e-06 GO:0046983 protein dimerization activity
1.67 3.61e-06 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.45 6.05e-06 GO:0008092 cytoskeletal protein binding
1.38 7.94e-06 GO:0003723 RNA binding
1.76 1.09e-05 GO:0004842 ubiquitin-protein ligase activity
1.99 1.18e-04 GO:0016566 specific transcriptional repressor activity
1.46 1.28e-04 GO:0060589 nucleoside-triphosphatase regulator activity
1.74 1.31e-04 GO:0008022 protein C-terminus binding
1.95 4.75e-04 GO:0051427 hormone receptor binding
1.73 5.18e-04 GO:0004721 phosphoprotein phosphatase activity
1.81 6.85e-04 GO:0051020 GTPase binding
1.44 8.30e-04 GO:0030695 GTPase regulator activity
1.56 8.80e-04 GO:0016791 phosphatase activity
1.91 1.03e-03 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
1.53 1.90e-03 GO:0005083 small GTPase regulator activity
1.70 3.53e-03 GO:0003702 RNA polymerase II transcription factor activity
2.79 4.85e-03 GO:0035064 methylated histone residue binding
1.42 5.04e-03 GO:0032403 protein complex binding
1.92 5.36e-03 GO:0035257 nuclear hormone receptor binding
1.47 7.27e-03 GO:0046982 protein heterodimerization activity
1.90 1.05e-02 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
1.75 1.23e-02 GO:0031267 small GTPase binding
1.42 1.25e-02 GO:0005525 GTP binding
2.46 1.28e-02 GO:0034061 DNA polymerase activity
1.35 1.33e-02 GO:0042803 protein homodimerization activity
1.65 1.76e-02 GO:0003690 double-stranded DNA binding
1.62 2.19e-02 GO:0000287 magnesium ion binding
1.75 2.77e-02 GO:0017016 Ras GTPase binding
2.08 2.97e-02 GO:0042826 histone deacetylase binding
1.79 3.33e-02 GO:0047485 protein N-terminus binding
2.44 4.11e-02 GO:0003887 DNA-directed DNA polymerase activity
1.81 4.25e-02 GO:0031625 ubiquitin protein ligase binding