Motif ID: TLX2.p2

Z-value: 1.566


Transcription factors associated with TLX2.p2:

Gene SymbolEntrez IDGene Name
Tlx2 21909 T-cell leukemia, homeobox 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Tlx2chr6_-_83020092-0.163.4e-02Click!


Activity profile for motif TLX2.p2.

activity profile for motif TLX2.p2


Sorted Z-values histogram for motif TLX2.p2

Sorted Z-values for motif TLX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_45401303 20.578 Col3a1
collagen, type III, alpha 1
chr1_+_45401659 18.753 Col3a1
collagen, type III, alpha 1
chr1_-_45559866 12.765 Col5a2
collagen, type V, alpha 2
chr1_-_45559904 12.359 Col5a2
collagen, type V, alpha 2
chr7_+_134355216 12.239 Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr7_+_134355120 12.132 NM_016754
Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr16_-_56886260 11.869 NM_019631
Tmem45a
transmembrane protein 45a
chr1_-_45559700 11.389 Col5a2
collagen, type V, alpha 2
chr10_+_79451332 11.341 NM_007725
Cnn2
calponin 2
chr10_+_97028456 11.041 Lum
lumican
chr10_+_79451369 10.508 Cnn2
calponin 2
chr11_-_78798332 10.477 NM_001159301
NM_010708
Lgals9

lectin, galactose binding, soluble 9

chr3_-_92819586 10.322 NM_028798
Crct1
cysteine-rich C-terminal 1
chr1_-_92740348 10.264 Col6a3
collagen, type VI, alpha 3
chr9_-_45743950 10.151 Tagln
transgelin
chr3_+_54165028 10.012 NM_001198765
NM_001198766
NM_015784
Postn


periostin, osteoblast specific factor


chr3_+_90472990 9.688 NM_013650
S100a8
S100 calcium binding protein A8 (calgranulin A)
chr9_-_66880619 9.335 Tpm1
tropomyosin 1, alpha
chr8_+_95351212 9.185 NM_008610
Mmp2
matrix metallopeptidase 2
chr9_-_45744036 9.028 NM_011526
Tagln
transgelin
chr7_-_149762919 9.004 H19
H19 fetal liver mRNA
chr1_-_45560001 8.889 NM_007737
Col5a2
collagen, type V, alpha 2
chr8_+_95376459 8.740 Mmp2
matrix metallopeptidase 2
chr10_+_97028409 8.118 Lum
lumican
chr3_+_90407688 8.013 NM_011311
S100a4
S100 calcium binding protein A4
chr1_+_45368443 8.011 Col3a1
collagen, type III, alpha 1
chr3_+_92483168 7.861 NM_028622
Lce1c
late cornified envelope 1C
chr2_-_84614976 7.731 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr3_-_92474213 7.590 NM_028625
Lce1a2
late cornified envelope 1A2
chr6_-_124586102 7.582 NM_173864
Gm5077
predicted gene 5077
chr15_+_54577256 7.549 NM_010930
Nov
nephroblastoma overexpressed gene
chr2_-_84614960 7.422 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr12_+_25393083 7.373 NM_009104
Rrm2
ribonucleotide reductase M2
chr8_-_26212588 7.321 Plekha2
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr9_-_21935019 7.109 NM_007388
Acp5
acid phosphatase 5, tartrate resistant
chr7_-_133606586 7.100 NM_007504
Atp2a1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr1_-_45460310 7.071 Col5a2
collagen, type V, alpha 2
chr19_-_34329804 7.036 NM_007392
Acta2
actin, alpha 2, smooth muscle, aorta
chr7_-_125629996 6.956 Itpripl2
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr7_-_133606617 6.840 Atp2a1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr3_+_93123668 6.839 NM_133698
Hrnr
hornerin
chrX_+_156146532 6.542 NM_021389
Sh3kbp1
SH3-domain kinase binding protein 1
chr1_-_45982242 6.315 NM_016917
Slc40a1
solute carrier family 40 (iron-regulated transporter), member 1
chr6_+_122463595 6.299 Mfap5
microfibrillar associated protein 5
chr6_+_4471231 6.281 Col1a2
collagen, type I, alpha 2
chr8_+_11443165 6.267 Col4a2
collagen, type IV, alpha 2
chr8_-_64238843 6.168 Palld
palladin, cytoskeletal associated protein
chr13_-_74946095 6.164 Cast
calpastatin
chr1_+_45368382 6.141 NM_009930
Col3a1
collagen, type III, alpha 1
chr16_-_45844409 6.120 NM_153412
Phldb2
pleckstrin homology-like domain, family B, member 2
chr6_+_135015679 6.105 NM_181444
Gprc5a
G protein-coupled receptor, family C, group 5, member A
chr8_-_64238814 6.102 Palld
palladin, cytoskeletal associated protein
chr4_-_63707849 6.026 Tnc
tenascin C
chr19_-_5924796 5.983 Cdc42ep2
CDC42 effector protein (Rho GTPase binding) 2
chr7_-_53176582 5.895 NM_010129
Emp3
epithelial membrane protein 3
chr3_-_92452189 5.748 NM_025984
Lce1a1
late cornified envelope 1A1
chr2_-_164182009 5.717 Slpi
secretory leukocyte peptidase inhibitor
chr11_-_83391984 5.695 Ccl9
chemokine (C-C motif) ligand 9
chr6_-_136890189 5.684 NM_007486
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr16_-_10314010 5.674 NM_007929
Emp2
epithelial membrane protein 2
chr16_-_10313963 5.651 Emp2
epithelial membrane protein 2
chr3_-_92582820 5.592 NM_029667
Lce1i
late cornified envelope 1I
chr1_-_71699671 5.402 NM_010233
Fn1
fibronectin 1
chr6_+_122463663 5.322 NM_015776
Mfap5
microfibrillar associated protein 5
chr3_+_92120626 5.307 NM_011469
Sprr2b
small proline-rich protein 2B
chr6_+_117118552 5.259 NM_001012477
NM_013655
NM_021704
Cxcl12


chemokine (C-X-C motif) ligand 12


chr9_+_110921791 5.231 NM_008522
Ltf
lactotransferrin
chr7_-_56103405 5.178 NM_001198841
Csrp3
cysteine and glycine-rich protein 3
chr18_-_52688607 5.170 Lox
lysyl oxidase
chr10_-_90545046 5.160 Apaf1
apoptotic peptidase activating factor 1
chr3_+_90318894 5.059 S100a13
S100 calcium binding protein A13
chr4_+_118104028 5.038 Elovl1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr11_-_54798601 5.007


chr10_-_117261663 4.954 Rap1b
RAS related protein 1b
chr12_+_114378688 4.925 Crip2
cysteine rich protein 2
chr3_-_92524255 4.906 NM_026394
Lce1f
late cornified envelope 1F
chr3_+_90318850 4.904 S100a13
S100 calcium binding protein A13
chr7_-_56103389 4.887 Csrp3
cysteine and glycine-rich protein 3
chr17_-_35973192 4.875 Tubb5
tubulin, beta 5
chr11_+_82930294 4.805 NM_011407
Slfn1
schlafen 1
chr11_-_75841236 4.752 NM_029658
Fam101b
family with sequence similarity 101, member B
chr2_+_164595447 4.728 Ube2c
ubiquitin-conjugating enzyme E2C
chr14_+_34899165 4.725 NM_013473
Anxa8
annexin A8
chr16_+_24721940 4.678 NM_001145954
Lpp
LIM domain containing preferred translocation partner in lipoma
chr7_+_135390325 4.658 NM_009365
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr5_+_17080553 4.641 NM_013657
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr10_+_79321979 4.632 Ptbp1
polypyrimidine tract binding protein 1
chr9_+_7764067 4.620 NM_133739
Tmem123
transmembrane protein 123
chr11_+_45869506 4.600 Adam19
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr19_-_46119403 4.556 Ldb1
LIM domain binding 1
chr11_+_61298923 4.504 NM_029568
Mfap4
microfibrillar-associated protein 4
chr2_+_164595415 4.499 NM_026785
Ube2c
ubiquitin-conjugating enzyme E2C
chr12_+_8778260 4.476 Sdc1
syndecan 1
chr17_+_34400152 4.468 NM_207105
H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr5_-_138312923 4.411 NM_001024932
Pilrb2
paired immunoglobin-like type 2 receptor beta 2
chr11_-_106576380 4.380 Pecam1
platelet/endothelial cell adhesion molecule 1
chr11_+_104469313 4.377 NM_016780
Itgb3
integrin beta 3
chr7_-_51787440 4.373 NM_019866
Spib
Spi-B transcription factor (Spi-1/PU.1 related)
chr17_-_12888210 4.364 Igf2r
insulin-like growth factor 2 receptor
chr9_+_62705890 4.352 NM_001102468
NM_138304
Calml4

calmodulin-like 4

chr1_-_132359220 4.345 Cd55
CD55 antigen
chr7_-_133512962 4.340 NM_010689
Lat
linker for activation of T cells
chr9_-_70269326 4.333 NM_007630
Ccnb2
cyclin B2
chr17_-_57367499 4.294 C3
complement component 3
chr3_+_87752614 4.277 NM_007759
Crabp2
cellular retinoic acid binding protein II
chr7_+_135390456 4.277 Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr2_-_72817058 4.273 Sp3
trans-acting transcription factor 3
chr8_-_64238879 4.271 Palld
palladin, cytoskeletal associated protein
chr6_-_99216494 4.258 NM_001197321
Foxp1
forkhead box P1
chr11_+_61298978 4.256 Mfap4
microfibrillar-associated protein 4
chr10_+_97028134 4.246 NM_008524
Lum
lumican
chr11_+_67013553 4.220 NM_030679
Myh1
myosin, heavy polypeptide 1, skeletal muscle, adult
chr16_-_36334417 4.202 NM_001001332
BC117090
cDNA sequence BC1179090
chrX_+_98644459 4.192 Itgb1bp2
integrin beta 1 binding protein 2
chr11_+_68970573 4.187 NM_009659
Alox12b
arachidonate 12-lipoxygenase, 12R type
chr5_+_8056508 4.170 NM_001080974
Sri
sorcin
chr18_+_60535680 4.158 NM_001146275
NM_021792
Iigp1

interferon inducible GTPase 1

chr2_+_33071451 4.147 NM_011923
Angptl2
angiopoietin-like 2
chr16_-_10313924 4.145 Emp2
epithelial membrane protein 2
chr10_-_111434231 4.140 Glipr1
GLI pathogenesis-related 1 (glioma)
chr16_-_45844343 4.131 Phldb2
pleckstrin homology-like domain, family B, member 2
chr11_+_68970595 4.129 Alox12b
arachidonate 12-lipoxygenase, 12R type
chr10_+_92951804 4.128 Hal
histidine ammonia lyase
chr13_-_93564652 4.123 NM_011582
Thbs4
thrombospondin 4
chr1_+_133535033 4.106 Ctse
cathepsin E
chr3_-_88307024 4.095 Lmna
lamin A
chr11_-_54846882 4.072 NM_001110211
NM_013472
Anxa6

annexin A6

chr19_-_57290515 4.062 NM_178688
Ablim1
actin-binding LIM protein 1
chr13_-_74945368 4.039 NM_009817
Cast
calpastatin
chr8_-_109927080 4.038 NM_008706
Nqo1
NAD(P)H dehydrogenase, quinone 1
chr7_+_108534039 4.031 NM_027180
Arap1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr11_-_20731016 4.028 NM_173752
1110067D22Rik
RIKEN cDNA 1110067D22 gene
chr3_-_92568947 4.021 NM_026335
Lce1h
late cornified envelope 1H
chr8_+_83017933 3.989 NM_010369
Gypa
glycophorin A
chr1_+_78813482 3.982 NM_021342
Kcne4
potassium voltage-gated channel, Isk-related subfamily, gene 4
chr6_+_29409404 3.978 Flnc
filamin C, gamma
chr1_-_132359292 3.971 NM_010016
Cd55
CD55 antigen
chr19_-_11340591 3.967 NM_007641
Ms4a1
membrane-spanning 4-domains, subfamily A, member 1
chr3_-_142058569 3.962 Pdlim5
PDZ and LIM domain 5
chr19_-_9162377 3.962 NM_011681
Scgb1a1
secretoglobin, family 1A, member 1 (uteroglobin)
chr16_+_49855786 3.957 Cd47
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr6_+_35202672 3.917 1810058I24Rik
RIKEN cDNA 1810058I24 gene
chr10_+_41196119 3.916 NM_001164433
NM_138315
Mical1

microtubule associated monoxygenase, calponin and LIM domain containing 1

chr5_+_93696645 3.890 Ccng2
cyclin G2
chr15_-_67008433 3.887 NM_009177
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr7_+_149628285 3.882 NM_009405
Tnni2
troponin I, skeletal, fast 2
chr12_+_112680868 3.863 Tnfaip2
tumor necrosis factor, alpha-induced protein 2
chr7_+_3655919 3.851 Rps9
ribosomal protein S9
chrX_+_93291377 3.846 NM_010833
Msn
moesin
chr17_+_35331446 3.796 NM_008518
Ltb
lymphotoxin B
chrX_+_33428784 3.793 NM_001009947
Dock11
dedicator of cytokinesis 11
chr13_+_3553690 3.790 Gdi2
guanosine diphosphate (GDP) dissociation inhibitor 2
chr5_+_93696566 3.755 NM_007635
Ccng2
cyclin G2
chr2_-_140497116 3.748 Flrt3
fibronectin leucine rich transmembrane protein 3
chr6_-_115758729 3.745 NM_172086
Rpl32
ribosomal protein L32
chr9_-_71440061 3.741 NM_001033208
Gcom1
GRINL1A complex locus
chr11_+_43287820 3.739 NM_026979
C1qtnf2
C1q and tumor necrosis factor related protein 2
chr8_+_70018744 3.738 NM_001168577
NM_010874
Nat2

N-acetyltransferase 2 (arylamine N-acetyltransferase)

chr19_-_5726221 3.737 NM_001114595
NM_001114596
NM_001114597
NM_053252
Ehbp1l1



EH domain binding protein 1-like 1



chr10_+_115254308 3.722 NM_001168679
NM_001168680
NM_146010
Tspan8


tetraspanin 8


chr15_-_34372832 3.717 NM_009083
NM_001163485
Rpl30

ribosomal protein L30

chr16_+_96422285 3.716 Sh3bgr
SH3-binding domain glutamic acid-rich protein
chr3_-_36374572 3.715 Anxa5
annexin A5
chr15_-_5193681 3.691 NM_001136079
NM_008965
Ptger4

prostaglandin E receptor 4 (subtype EP4)

chr5_-_138277390 3.684 Pilra
paired immunoglobin-like type 2 receptor alpha
chr11_+_43287798 3.673 C1qtnf2
C1q and tumor necrosis factor related protein 2
chr2_-_119980210 3.672 Ehd4
EH-domain containing 4
chrX_+_98644445 3.667 NM_013712
Itgb1bp2
integrin beta 1 binding protein 2
chr15_+_78813524 3.662 Triobp
TRIO and F-actin binding protein
chr17_-_7997838 3.649 NM_001081416
Fndc1
fibronectin type III domain containing 1
chr12_+_8778152 3.647 Sdc1
syndecan 1
chr4_+_118100682 3.631 NM_001039175
NM_019422
Elovl1

elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1

chr17_-_57367542 3.610 NM_009778
C3
complement component 3
chr3_-_142058595 3.609 NM_001190852
NM_001190853
NM_001190854
NM_001190855
NM_001190856
NM_019808
NM_019809
Pdlim5






PDZ and LIM domain 5






chr17_-_45730551 3.609 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr18_+_20469364 3.596 NM_010079
Dsg1a
desmoglein 1 alpha
chr9_+_46036788 3.590 Apoa1
apolipoprotein A-I
chr15_+_81977766 3.587 Srebf2
sterol regulatory element binding factor 2
chr16_+_14163414 3.571 Nde1
nuclear distribution gene E homolog 1 (A nidulans)
chr12_+_112680869 3.571 NM_009396
Tnfaip2
tumor necrosis factor, alpha-induced protein 2
chr2_-_140497204 3.569 NM_001172160
NM_178382
Flrt3

fibronectin leucine rich transmembrane protein 3

chr19_-_4190836 3.565 NM_178650
Tbc1d10c
TBC1 domain family, member 10c
chr9_-_110649625 3.556 NM_011199
Pth1r
parathyroid hormone 1 receptor
chr3_-_36374562 3.555 Anxa5
annexin A5
chr7_+_3293008 3.545 NM_001093766
Myadm
myeloid-associated differentiation marker
chr7_+_50663608 3.541 NM_172900
Siglecg
sialic acid binding Ig-like lectin G
chr11_+_109512220 3.502 NM_021880
Prkar1a
protein kinase, cAMP dependent regulatory, type I, alpha
chr2_-_140497183 3.499 Flrt3
fibronectin leucine rich transmembrane protein 3
chr6_-_87285690 3.489 NM_054041
Antxr1
anthrax toxin receptor 1
chr17_+_35576081 3.473 NM_001198560
NM_001198561
NM_010394
H2-Q9
H2-Q7


histocompatibility 2, Q region locus 9
histocompatibility 2, Q region locus 7


chr7_-_141416778 3.469 NM_007400
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr17_-_45724536 3.469 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr9_-_45012097 3.456 NM_145403
Tmprss4
transmembrane protease, serine 4
chr2_-_73367455 3.436 NM_153138
Wipf1
WAS/WASL interacting protein family, member 1
chr3_-_36374517 3.433 Anxa5
annexin A5
chr3_+_159502646 3.431 NM_026582
Wls
wntless homolog (Drosophila)
chr5_-_17341534 3.429 Cd36
CD36 antigen
chr9_+_46036703 3.418 NM_009692
Apoa1
apolipoprotein A-I
chr14_-_56407622 3.411 NM_001164107
NM_001164108
NM_019955
Ripk3


receptor-interacting serine-threonine kinase 3


chrX_+_71516128 3.388 NM_052835
Rpl10
ribosomal protein 10

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.58 8.93e-13 GO:0048518 positive regulation of biological process
1.59 1.72e-11 GO:0048522 positive regulation of cellular process
2.03 8.84e-11 GO:0002376 immune system process
1.70 2.40e-09 GO:0048583 regulation of response to stimulus
1.26 2.81e-09 GO:0008152 metabolic process
4.58 9.98e-09 GO:0006414 translational elongation
1.30 1.90e-07 GO:0043170 macromolecule metabolic process
1.26 2.40e-07 GO:0044238 primary metabolic process
1.88 2.82e-07 GO:0009888 tissue development
1.49 3.32e-07 GO:0048731 system development
1.45 6.66e-07 GO:0048856 anatomical structure development
1.25 6.69e-07 GO:0044237 cellular metabolic process
1.58 8.00e-07 GO:0048513 organ development
1.42 1.05e-06 GO:0071840 cellular component organization or biogenesis
1.43 1.24e-06 GO:0016043 cellular component organization
2.02 3.15e-06 GO:0002682 regulation of immune system process
1.38 7.54e-06 GO:0032502 developmental process
1.13 8.63e-06 GO:0009987 cellular process
1.39 9.63e-06 GO:0007275 multicellular organismal development
1.42 1.08e-05 GO:0019538 protein metabolic process
1.85 1.46e-05 GO:0048584 positive regulation of response to stimulus
1.65 3.12e-05 GO:0009966 regulation of signal transduction
2.03 3.52e-05 GO:0072358 cardiovascular system development
2.03 3.52e-05 GO:0072359 circulatory system development
1.28 7.40e-05 GO:0044260 cellular macromolecule metabolic process
1.42 8.33e-05 GO:0048519 negative regulation of biological process
1.47 3.49e-04 GO:0065008 regulation of biological quality
1.69 3.96e-04 GO:0042127 regulation of cell proliferation
1.56 4.18e-04 GO:0031325 positive regulation of cellular metabolic process
2.08 6.43e-04 GO:0009611 response to wounding
1.71 6.77e-04 GO:0051128 regulation of cellular component organization
1.55 7.34e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.33 7.47e-04 GO:0009058 biosynthetic process
1.91 8.41e-04 GO:0008284 positive regulation of cell proliferation
1.39 1.63e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.51 1.82e-03 GO:0009893 positive regulation of metabolic process
1.92 1.91e-03 GO:0009967 positive regulation of signal transduction
1.46 2.91e-03 GO:0006950 response to stress
2.15 4.33e-03 GO:0001568 blood vessel development
1.38 4.59e-03 GO:0071842 cellular component organization at cellular level
1.38 4.72e-03 GO:0048523 negative regulation of cellular process
1.31 5.27e-03 GO:0044249 cellular biosynthetic process
4.99 5.39e-03 GO:0048002 antigen processing and presentation of peptide antigen
1.93 5.56e-03 GO:0051247 positive regulation of protein metabolic process
1.26 5.93e-03 GO:0019222 regulation of metabolic process
2.06 6.39e-03 GO:0048534 hemopoietic or lymphoid organ development
1.94 6.82e-03 GO:0032270 positive regulation of cellular protein metabolic process
2.07 7.57e-03 GO:0001944 vasculature development
2.12 8.81e-03 GO:0033043 regulation of organelle organization
1.47 9.17e-03 GO:0023051 regulation of signaling
1.48 1.02e-02 GO:0009653 anatomical structure morphogenesis
1.27 1.02e-02 GO:0031323 regulation of cellular metabolic process
2.00 1.13e-02 GO:0002520 immune system development
1.35 1.41e-02 GO:0044267 cellular protein metabolic process
4.60 1.44e-02 GO:0010464 regulation of mesenchymal cell proliferation
1.32 1.50e-02 GO:0010467 gene expression
2.11 1.60e-02 GO:0006412 translation
2.50 1.63e-02 GO:0007517 muscle organ development
1.53 1.77e-02 GO:0010646 regulation of cell communication
1.98 1.85e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.14 1.89e-02 GO:0065007 biological regulation
3.92 1.97e-02 GO:0019882 antigen processing and presentation
2.14 2.62e-02 GO:0061061 muscle structure development
1.43 2.69e-02 GO:0051239 regulation of multicellular organismal process
1.26 2.87e-02 GO:0080090 regulation of primary metabolic process
1.89 3.02e-02 GO:0002684 positive regulation of immune system process
1.26 3.36e-02 GO:0060255 regulation of macromolecule metabolic process
1.39 3.41e-02 GO:0042221 response to chemical stimulus
1.75 3.64e-02 GO:0010647 positive regulation of cell communication
4.58 3.75e-02 GO:0002053 positive regulation of mesenchymal cell proliferation
2.48 4.21e-02 GO:0042060 wound healing
1.74 4.36e-02 GO:0023056 positive regulation of signaling
1.56 4.37e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
2.02 4.48e-02 GO:0030097 hemopoiesis
2.94 4.83e-02 GO:0034504 protein localization to nucleus
1.88 4.98e-02 GO:0006955 immune response
1.88 4.98e-02 GO:0010627 regulation of intracellular protein kinase cascade

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.31 2.07e-17 GO:0005737 cytoplasm
1.22 6.55e-17 GO:0005622 intracellular
1.23 9.28e-17 GO:0044424 intracellular part
1.24 1.26e-13 GO:0043226 organelle
1.36 2.02e-13 GO:0044444 cytoplasmic part
1.24 3.49e-13 GO:0043229 intracellular organelle
1.43 1.50e-12 GO:0044422 organelle part
1.40 8.21e-11 GO:0044446 intracellular organelle part
1.45 4.56e-10 GO:0032991 macromolecular complex
1.51 9.03e-09 GO:0043228 non-membrane-bounded organelle
1.51 9.03e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.86 1.34e-08 GO:0044421 extracellular region part
1.21 1.63e-08 GO:0043227 membrane-bounded organelle
1.66 2.27e-08 GO:0005829 cytosol
1.21 3.25e-08 GO:0043231 intracellular membrane-bounded organelle
1.10 1.74e-07 GO:0005623 cell
1.10 1.74e-07 GO:0044464 cell part
1.53 1.40e-06 GO:0005576 extracellular region
1.40 3.71e-06 GO:0043234 protein complex
2.93 4.80e-06 GO:0005840 ribosome
1.82 1.70e-05 GO:0005615 extracellular space
1.96 1.23e-04 GO:0009986 cell surface
3.01 3.88e-04 GO:0044445 cytosolic part
2.18 6.38e-04 GO:0015629 actin cytoskeleton
1.46 1.03e-03 GO:0005856 cytoskeleton
1.42 1.23e-03 GO:0031974 membrane-enclosed lumen
2.03 1.90e-03 GO:0031012 extracellular matrix
1.42 1.99e-03 GO:0070013 intracellular organelle lumen
2.10 2.05e-03 GO:0005578 proteinaceous extracellular matrix
1.41 2.21e-03 GO:0043233 organelle lumen
1.62 2.77e-03 GO:0012505 endomembrane system
5.96 2.99e-03 GO:0042611 MHC protein complex
2.25 4.20e-03 GO:0009897 external side of plasma membrane
2.70 4.49e-03 GO:0043292 contractile fiber
4.03 4.56e-03 GO:0022626 cytosolic ribosome
1.80 5.01e-03 GO:0030529 ribonucleoprotein complex
1.52 5.63e-03 GO:0005654 nucleoplasm
1.37 6.00e-03 GO:0044459 plasma membrane part
1.20 6.63e-03 GO:0005634 nucleus
1.24 9.00e-03 GO:0071944 cell periphery
1.37 9.76e-03 GO:0044428 nuclear part
1.41 1.06e-02 GO:0031981 nuclear lumen
2.77 1.11e-02 GO:0044449 contractile fiber part
3.71 1.19e-02 GO:0015935 small ribosomal subunit
1.52 1.38e-02 GO:0005626 insoluble fraction
5.04 1.46e-02 GO:0005581 collagen
2.85 1.90e-02 GO:0030017 sarcomere
1.43 2.74e-02 GO:0000267 cell fraction
2.32 2.81e-02 GO:0000139 Golgi membrane
3.91 2.93e-02 GO:0001725 stress fiber

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.44 1.45e-20 GO:0005515 protein binding
1.24 8.50e-19 GO:0005488 binding
1.66 4.34e-05 GO:0005102 receptor binding
3.24 4.68e-05 GO:0003735 structural constituent of ribosome
2.11 5.24e-05 GO:0005198 structural molecule activity
1.90 2.40e-04 GO:0008092 cytoskeletal protein binding
2.14 9.28e-04 GO:0003779 actin binding