Motif ID: TP53.p2

Z-value: 0.678


Transcription factors associated with TP53.p2:

Gene SymbolEntrez IDGene Name
Trp53 22059 transformation related protein 53

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Trp53chr11_+_69393851-0.138.3e-02Click!


Activity profile for motif TP53.p2.

activity profile for motif TP53.p2


Sorted Z-values histogram for motif TP53.p2

Sorted Z-values for motif TP53.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TP53.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_148478321 10.175 Dffa
DNA fragmentation factor, alpha subunit
chr4_+_148478238 9.257 NM_001025296
NM_010044
 Dffa

DNA fragmentation factor, alpha subunit

chr9_-_123760992 9.173 NM_001110253
 Fyco1
FYVE and coiled-coil domain containing 1
chr9_-_123760686 7.035 NM_148925
 Fyco1
FYVE and coiled-coil domain containing 1
chr11_-_106163120 4.781 NM_008117
 Gh
growth hormone
chr4_+_148478290 4.779 Dffa
DNA fragmentation factor, alpha subunit
chr1_-_21952022 4.128 NM_001160139
NM_023872
 Kcnq5

potassium voltage-gated channel, subfamily Q, member 5

chr8_-_86265035 4.033 NM_001163029
NM_001163030
NM_001163031
NM_011925
 Cd97



CD97 antigen



chr6_-_115708978 3.830 Tmem40
transmembrane protein 40
chr11_-_40568710 3.795 NM_009831
 Ccng1
cyclin G1
chr9_-_34983552 3.284 NM_027030
 Dcps
decapping enzyme, scavenger
chr7_-_148068161 2.889 NM_022433
 Sirt3
sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae)
chr7_+_109416314 2.700 NM_009287
 Stim1
stromal interaction molecule 1
chr6_-_115709004 2.616 NM_144805
 Tmem40
transmembrane protein 40
chr1_-_17087821 2.612 NM_020604
 Jph1
junctophilin 1
chr1_-_17087915 2.571 Jph1
junctophilin 1
chr11_+_60351159 2.555 NM_172943
 Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr1_-_21951497 2.547 Kcnq5
potassium voltage-gated channel, subfamily Q, member 5
chr12_+_77471173 2.465 NM_178744
 Zbtb1
zinc finger and BTB domain containing 1
chr16_-_4523061 2.367 Srl
sarcalumenin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
1.75 4.34e-02 GO:0006464 protein modification process
1.73 4.47e-02 GO:0043412 macromolecule modification
1.33 1.22e-02 GO:0044238 primary metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
2.32 1.36e-02 GO:0015630 microtubule cytoskeleton
1.27 2.05e-03 GO:0005737 cytoplasm
1.22 1.33e-02 GO:0043226 organelle
1.18 1.56e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
Enrichment   P-value GO Accession GO Term
2.69 7.77e-03 GO:0004674 protein serine/threonine kinase activity
2.25 4.28e-02 GO:0004672 protein kinase activity
2.23 2.49e-03 GO:0016301 kinase activity
2.07 5.14e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.79 1.11e-02 GO:0030554 adenyl nucleotide binding
1.79 1.22e-02 GO:0005524 ATP binding
1.76 1.93e-02 GO:0032559 adenyl ribonucleotide binding
1.65 3.94e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.64 4.05e-02 GO:0017076 purine nucleotide binding
1.57 4.89e-02 GO:0000166 nucleotide binding
1.53 1.66e-03 GO:0046872 metal ion binding
1.51 2.74e-03 GO:0043169 cation binding
1.50 3.20e-03 GO:0043167 ion binding
1.35 1.38e-02 GO:0003824 catalytic activity