• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: TP53.p2

Z-value: 0.678

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_148478321	10.175		Dffa	DNA fragmentation factor, alpha subunit
chr4_+_148478238	9.257	NM_001025296 NM_010044	Dffa	DNA fragmentation factor, alpha subunit
chr9_-_123760992	9.173	NM_001110253	Fyco1	FYVE and coiled-coil domain containing 1
chr9_-_123760686	7.035	NM_148925	Fyco1	FYVE and coiled-coil domain containing 1
chr11_-_106163120	4.781	NM_008117	Gh	growth hormone
chr4_+_148478290	4.779		Dffa	DNA fragmentation factor, alpha subunit
chr1_-_21952022	4.128	NM_001160139 NM_023872	Kcnq5	potassium voltage-gated channel, subfamily Q, member 5
chr8_-_86265035	4.033	NM_001163029 NM_001163030 NM_001163031 NM_011925	Cd97	CD97 antigen
chr6_-_115708978	3.830		Tmem40	transmembrane protein 40
chr11_-_40568710	3.795	NM_009831	Ccng1	cyclin G1
chr9_-_34983552	3.284	NM_027030	Dcps	decapping enzyme, scavenger
chr7_-_148068161	2.889	NM_022433	Sirt3	sirtuin 3 (silent mating type information regulation 2, homolog) 3 (S. cerevisiae)
chr7_+_109416314	2.700	NM_009287	Stim1	stromal interaction molecule 1
chr6_-_115709004	2.616	NM_144805	Tmem40	transmembrane protein 40
chr1_-_17087821	2.612	NM_020604	Jph1	junctophilin 1
chr1_-_17087915	2.571		Jph1	junctophilin 1
chr11_+_60351159	2.555	NM_172943	Alkbh5	alkB, alkylation repair homolog 5 (E. coli)
chr1_-_21951497	2.547		Kcnq5	potassium voltage-gated channel, subfamily Q, member 5
chr12_+_77471173	2.465	NM_178744	Zbtb1	zinc finger and BTB domain containing 1
chr16_-_4523061	2.367		Srl	sarcalumenin
chr11_-_78959855	2.297	NM_013571	Ksr1	kinase suppressor of ras 1
chr11_-_78959969	2.293		Ksr1	kinase suppressor of ras 1
chr4_+_124419115	2.284	NM_008385	Inpp5b	inositol polyphosphate-5-phosphatase B
chr6_-_136610399	2.237	NM_025806	Plbd1	phospholipase B domain containing 1
chr12_+_113858217	2.235	NM_007421	Adssl1	adenylosuccinate synthetase like 1
chr16_-_10542689	2.224		Dexi	dexamethasone-induced transcript
chr11_-_40568524	2.040		Ccng1	cyclin G1
chr14_-_73725546	2.036		Rb1	retinoblastoma 1
chr14_-_73725576	2.032	NM_009029	Rb1	retinoblastoma 1
chr6_-_136610311	1.977		Plbd1	phospholipase B domain containing 1
chr11_-_109334909	1.962	NM_001029842	Slc16a6	solute carrier family 16 (monocarboxylic acid transporters), member 6
chr2_-_154900160	1.913		Ahcy	S-adenosylhomocysteine hydrolase
chr12_+_107248419	1.854	NM_001029843 NM_001029844 NM_011705	Vrk1	vaccinia related kinase 1
chr16_-_10543121	1.818	NM_021428	Dexi	dexamethasone-induced transcript
chr2_-_154900188	1.762	NM_016661	Ahcy	S-adenosylhomocysteine hydrolase
chr2_-_25877230	1.757	NM_133835	Ubac1	ubiquitin associated domain containing 1
chr4_-_106850812	1.649	NM_025617	2210012G02Rik	RIKEN cDNA 2210012G02 gene
chr9_-_121825422	1.641	NM_010012	Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1
chr12_+_107248496	1.628		Vrk1	vaccinia related kinase 1
chr2_-_154900132	1.597		Ahcy	S-adenosylhomocysteine hydrolase
chr17_-_31992708	1.582	NM_010831	Sik1	salt inducible kinase 1
chrX_-_35988248	1.575		C1galt1c1	C1GALT1-specific chaperone 1
chr12_-_105094033	1.549		Serpina1a	serine (or cysteine) peptidase inhibitor, clade A, member 1A
chr9_-_121825407	1.538		Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1
chr17_+_3326513	1.519	NM_001122998	Tiam2	T-cell lymphoma invasion and metastasis 2
chr1_+_54307526	1.495	NM_030025	Ccdc150	coiled-coil domain containing 150
chr19_-_47212695	1.482	NM_133746	Calhm2	calcium homeostasis modulator 2
chr11_-_5442157	1.391	NM_134033	Ccdc117	coiled-coil domain containing 117
chr11_-_12364754	1.381		Cobl	cordon-bleu
chr7_+_107855164	1.366		Fam168a	family with sequence similarity 168, member A
chr2_-_163223660	1.359	NM_021566	Jph2	junctophilin 2
chr8_+_97876182	1.344	NM_008609	Mmp15	matrix metallopeptidase 15
chr3_+_79395257	1.334		Ppid	peptidylprolyl isomerase D (cyclophilin D)
chr3_+_79395280	1.314	NM_026352	Ppid	peptidylprolyl isomerase D (cyclophilin D)
chr13_-_61037960	1.309	NM_007796	Ctla2a	cytotoxic T lymphocyte-associated protein 2 alpha
chr9_+_72833379	1.245		Ccpg1	cell cycle progression 1
chr15_-_77585658	1.240	NM_001081970	Apol8	apolipoprotein L 8
chr6_+_142705178	1.195	NM_009908	Cmas	cytidine monophospho-N-acetylneuraminic acid synthetase
chr17_+_36131397	1.182		A930015D03Rik	RIKEN cDNA A930015D03 gene
chr18_+_66618186	1.177	NM_021451	Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1
chr8_+_75095914	1.170	NM_144534	Nwd1 Tmem38a	NACHT and WD repeat domain containing 1 transmembrane protein 38A
chr2_+_118489457	1.168		Pak6	p21 protein (Cdc42/Rac)-activated kinase 6
chr7_+_16894925	1.155	NM_133234	Bbc3	BCL2 binding component 3
chr4_+_155336386	1.129	NM_026125	Fam132a	family with sequence similarity 132, member A
chr8_+_96910392	1.090	NM_022331	Herpud1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr5_-_108416027	1.080	NM_026062	Fam69a	family with sequence similarity 69, member A
chr4_-_43512476	1.055	NM_001013377	E130306D19Rik	RIKEN cDNA E130306D19 gene
chr18_-_20160536	1.052	NM_007882	Dsc3	desmocollin 3
chr7_+_17428258	1.052		Prkd2	protein kinase D2
chr4_+_106851234	1.044	NM_029565	Tmem59	transmembrane protein 59
chr17_+_87682206	1.039	NM_028639	Ttc7	tetratricopeptide repeat domain 7
chr11_-_53520771	1.029		Rad50	RAD50 homolog (S. cerevisiae)
chr2_-_104334610	1.027	NM_001145824 NM_010434	Hipk3	homeodomain interacting protein kinase 3
chr9_+_72833327	1.026	NM_001114328 NM_028181	Ccpg1	cell cycle progression 1
chr12_-_71203819	1.009	NM_001081453	Nin	ninein
chr15_+_80808238	1.004		Sgsm3	small G protein signaling modulator 3
chr2_-_91864276	0.988	NM_011957	Creb3l1	cAMP responsive element binding protein 3-like 1
chr18_+_57514370	0.971	NM_028447	Prrc1	proline-rich coiled-coil 1
chr7_-_26022753	0.969	NM_001031667	Gsk3a	glycogen synthase kinase 3 alpha
chr9_+_51573434	0.967	NM_175535	Arhgap20	Rho GTPase activating protein 20
chr6_-_116411041	0.966	NM_009662	Alox5	arachidonate 5-lipoxygenase
chr12_+_3365295	0.946		Kif3c	kinesin family member 3C
chr6_+_66986637	0.945		E230016M11Rik	RIKEN cDNA E230016M11 gene
chr7_-_35437859	0.943	NM_146188	Kctd15	potassium channel tetramerisation domain containing 15
chr8_-_118230828	0.916		Maf	avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr12_+_84861415	0.909	NM_030246	Dcaf4	DDB1 and CUL4 associated factor 4
chr11_-_116099404	0.905	NM_025276	Evpl	envoplakin
chr15_+_80808194	0.905	NM_134091	Sgsm3	small G protein signaling modulator 3
chr3_-_135354500	0.884	NM_008689	Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
chr4_+_155336456	0.870		Fam132a	family with sequence similarity 132, member A
chr2_+_25098448	0.866	NM_176834	Rnf208	ring finger protein 208
chr2_-_180655611	0.863	NM_173761	Ythdf1	YTH domain family 1
chr2_-_25877064	0.860		Ubac1	ubiquitin associated domain containing 1
chr2_-_104334599	0.849
chr10_-_34138271	0.848	NM_176968	Nt5dc1	5'-nucleotidase domain containing 1
chr10_+_110601745	0.842	NM_001003717 NM_175489	Osbpl8	oxysterol binding protein-like 8
chr11_-_59104252	0.842	NM_009522	Wnt3a	wingless-related MMTV integration site 3A
chr4_+_62069853	0.842		Prpf4	PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr2_+_91096984	0.823		Pacsin3	protein kinase C and casein kinase substrate in neurons 3
chr7_+_107855215	0.818	NM_178764	Fam168a	family with sequence similarity 168, member A
chr10_-_128002987	0.789	NM_011119	Pa2g4	proliferation-associated 2G4
chr8_+_3493117	0.785	NM_080461	Zfp358	zinc finger protein 358
chr4_-_57156022	0.781	NM_019427	Epb4.1l4b	erythrocyte protein band 4.1-like 4b
chr15_-_37890703	0.781	NM_199476	Rrm2b	ribonucleotide reductase M2 B (TP53 inducible)
chr14_-_55613384	0.777	NM_080728	Myh7	myosin, heavy polypeptide 7, cardiac muscle, beta
chr13_+_44826121	0.751	NM_021878	Jarid2	jumonji, AT rich interactive domain 2
chr1_+_132613903	0.746	NM_178691	Yod1	YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae)
chr3_-_135354151	0.736		Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
chr17_-_33897428	0.732	NM_008997	Rab11b	RAB11B, member RAS oncogene family
chr15_-_78136047	0.730		Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr18_+_4634926	0.713	NM_001081963	9430020K01Rik	RIKEN cDNA 9430020K01 gene
chr12_+_3365147	0.702		Kif3c	kinesin family member 3C
chr6_-_99616745	0.700	NM_025829	Eif4e3	eukaryotic translation initiation factor 4E member 3
chr9_+_65193874	0.697	NM_016688	Pdcd7	programmed cell death 7
chr4_+_62069801	0.685	NM_027297	Prpf4	PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr7_+_134388553	0.685		Zfp771	zinc finger protein 771
chr11_-_63735652	0.668	NM_018805	Hs3st3b1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr4_-_118846799	0.658	NM_001145936	Zfp691	zinc finger protein 691
chr10_-_128002991	0.650		Pa2g4	proliferation-associated 2G4
chr17_+_74927634	0.644	NM_007566	Birc6	baculoviral IAP repeat-containing 6
chr11_+_78075242	0.643	NM_001002004	2610507B11Rik	RIKEN cDNA 2610507B11 gene
chr7_-_145589409	0.643	NM_183289	Tcerg1l	transcription elongation regulator 1-like
chr19_+_6401701	0.636		Rasgrp2	RAS, guanyl releasing protein 2
chr7_+_140050907	0.629	NM_198017	Fam175b	family with sequence similarity 175, member B
chr7_+_86956134	0.629		Mesp2	mesoderm posterior 2
chr4_+_140977621	0.626		Hspb7	heat shock protein family, member 7 (cardiovascular)
chr10_+_121078708	0.618	NM_177335	D930020B18Rik	RIKEN cDNA D930020B18 gene
chr16_-_13730474	0.617	NM_011987	Pla2g10	phospholipase A2, group X
chr8_-_23763885	0.610	NM_011130	Polb	polymerase (DNA directed), beta
chr19_-_7008874	0.609	NM_008431	Kcnk4	potassium channel, subfamily K, member 4
chr15_-_78633301	0.599	NM_130859	Card10	caspase recruitment domain family, member 10
chr19_-_45734544	0.599	NM_013907	Fbxw4	F-box and WD-40 domain protein 4
chr4_-_57155985	0.592		Epb4.1l4b	erythrocyte protein band 4.1-like 4b
chr18_+_82644510	0.591	NM_001025245 NM_010777	Mbp	myelin basic protein
chr4_+_151460980	0.590		Plekhg5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr17_+_50648736	0.580	NM_013880	Plcl2	phospholipase C-like 2
chr4_+_154338216	0.570	NM_172990	Pank4	pantothenate kinase 4
chr17_+_29227908	0.569	NM_001111099	Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)
chr14_+_57021419	0.567	NM_001033043	Rnf17	ring finger protein 17
chr1_+_195128163	0.567	NM_008484	Lamb3	laminin, beta 3
chr12_+_10397567	0.563	NM_023697	Rdh14	retinol dehydrogenase 14 (all-trans and 9-cis)
chr15_+_84847570	0.558	NM_023478	Upk3a	uroplakin 3A
chr11_-_86807216	0.555	NM_001005341	Ypel2	yippee-like 2 (Drosophila)
chr3_+_32716447	0.553	NM_001013024	Usp13	ubiquitin specific peptidase 13 (isopeptidase T-3)
chr19_-_34953614	0.552		Pank1	pantothenate kinase 1
chr13_-_60998747	0.552	NM_001145801 NM_007797	Ctla2b	cytotoxic T lymphocyte-associated protein 2 beta
chr13_-_53472732	0.544		Sptlc1	serine palmitoyltransferase, long chain base subunit 1
chr11_-_80593259	0.538	NM_177390	Myo1d	myosin ID
chr9_-_66823199	0.536	NM_030717	Lactb	lactamase, beta
chrX_-_35988178	0.535		C1galt1c1	C1GALT1-specific chaperone 1
chr9_-_36604816	0.527		Ei24	etoposide induced 2.4 mRNA
chr4_-_118293009	0.525	NM_026789	Wdr65	WD repeat domain 65
chr7_+_17428413	0.524	NM_178900	Prkd2	protein kinase D2
chr3_+_40698182	0.522	NM_026622	3110057O12Rik	RIKEN cDNA 3110057O12 gene
chr17_+_25325344	0.518	NM_001197024	Unkl	unkempt-like (Drosophila)
chr7_-_20043842	0.515	NM_172279	Mark4	MAP/microtubule affinity-regulating kinase 4
chr5_+_108561892	0.508	NM_028481	Ccdc18	coiled-coil domain containing 18
chr14_+_34899165	0.504	NM_013473	Anxa8	annexin A8
chr9_-_36604652	0.499	NM_007915	Ei24	etoposide induced 2.4 mRNA
chr9_-_57493393	0.497		Csk	c-src tyrosine kinase
chr7_+_6124083	0.489	NM_001146024 NM_028316	Zfp444	zinc finger protein 444
chr7_+_51640108	0.487		Syt3	synaptotagmin III
chr13_-_35085906	0.474		Peci	peroxisomal delta3, delta2-enoyl-Coenzyme A isomerase
chr4_-_49533914	0.473	NM_178603	Mrpl50	mitochondrial ribosomal protein L50
chr9_-_121614076	0.470	NM_001164562 NM_178677	Sec22c	SEC22 vesicle trafficking protein homolog C (S. cerevisiae)
chr9_-_69989285	0.468	NM_029784	Fam81a	family with sequence similarity 81, member A
chr11_+_60351469	0.467		Alkbh5	alkB, alkylation repair homolog 5 (E. coli)
chr1_-_138157449	0.467	NM_001101516	Gpr25	G protein-coupled receptor 25
chr4_+_140977613	0.465		Hspb7	heat shock protein family, member 7 (cardiovascular)
chr9_-_22272737	0.457	NM_018739	rp9	retinitis pigmentosa 9 (human)
chr13_+_38436987	0.454		Bmp6	bone morphogenetic protein 6
chr2_-_170322575	0.450	NM_009996	Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1
chrX_-_35988279	0.448	NM_021550	C1galt1c1	C1GALT1-specific chaperone 1
chrX_+_71422597	0.446	NM_031379	Tktl1	transketolase-like 1
chr4_-_150379857	0.441		Per3	period homolog 3 (Drosophila)
chr2_+_72123858	0.440		B230120H23Rik	RIKEN cDNA B230120H23 gene
chr12_+_3365102	0.440	NM_008445	Kif3c	kinesin family member 3C
chr18_-_67884185	0.440	NM_001127177 NM_008977	Ptpn2	protein tyrosine phosphatase, non-receptor type 2
chr5_-_135164426	0.439	NM_010717	Limk1	LIM-domain containing, protein kinase
chr18_+_82644535	0.435		Mbp	myelin basic protein
chr9_+_100978450	0.433	NM_001100451	Msl2	male-specific lethal 2 homolog (Drosophila)
chr13_-_53472719	0.432	NM_009269	Sptlc1	serine palmitoyltransferase, long chain base subunit 1
chr6_-_142519807	0.427	NM_008428	Kcnj8	potassium inwardly-rectifying channel, subfamily J, member 8
chr3_+_28680248	0.420		Eif5a2	eukaryotic translation initiation factor 5A2
chr7_-_112885071	0.419		Rrp8	ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr10_+_93103715	0.411	NM_021320	Ntn4	netrin 4
chr4_-_62069611	0.411	NM_139291	Cdc26	cell division cycle 26
chr7_-_35174519	0.406	NM_025948	Lsm14a	LSM14 homolog A (SCD6, S. cerevisiae)
chr4_-_115612507	0.405	NM_001025567 NM_130865	Dmbx1	diencephalon/mesencephalon homeobox 1
chr5_-_30399962	0.402	NM_021288	Tyms	thymidylate synthase
chr8_-_109572384	0.397	NM_026513	Pdf	peptide deformylase (mitochondrial)
chr4_-_141279303	0.391	NM_001017966	Ddi2	DNA-damage inducible protein 2
chr6_+_90554873	0.386	NM_027868	Slc41a3	solute carrier family 41, member 3
chr17_+_56904233	0.378		Dus3l	dihydrouridine synthase 3-like (S. cerevisiae)
chr9_+_32503600	0.377	NM_001038642 NM_011808	Ets1	E26 avian leukemia oncogene 1, 5' domain
chr11_-_53520811	0.375	NM_009012	Rad50	RAD50 homolog (S. cerevisiae)
chr4_-_133801438	0.375	NM_024215	Zfp593	zinc finger protein 593
chr4_+_132567420	0.372	NM_146155	Ahdc1	AT hook, DNA binding motif, containing 1
chr4_-_153471168	0.368	NM_001126330 NM_001126331	Trp73	transformation related protein 73
chr14_-_21167291	0.361	NM_027475	Ecd	ecdysoneless homolog (Drosophila)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.33	1.22e-02	GO:0044238	primary metabolic process
1.75	4.34e-02	GO:0006464	protein modification process
1.73	4.47e-02	GO:0043412	macromolecule modification

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.27	2.05e-03	GO:0005737	cytoplasm
1.22	1.33e-02	GO:0043226	organelle
2.32	1.36e-02	GO:0015630	microtubule cytoskeleton
1.18	1.56e-02	GO:0005622	intracellular

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.53	1.66e-03	GO:0046872	metal ion binding
2.23	2.49e-03	GO:0016301	kinase activity
1.51	2.74e-03	GO:0043169	cation binding
1.50	3.20e-03	GO:0043167	ion binding
2.07	5.14e-03	GO:0016772	transferase activity, transferring phosphorus-containing groups
2.69	7.77e-03	GO:0004674	protein serine/threonine kinase activity
1.79	1.11e-02	GO:0030554	adenyl nucleotide binding
1.79	1.22e-02	GO:0005524	ATP binding
1.35	1.38e-02	GO:0003824	catalytic activity
1.76	1.93e-02	GO:0032559	adenyl ribonucleotide binding
1.65	3.94e-02	GO:0035639	purine ribonucleoside triphosphate binding
1.64	4.05e-02	GO:0017076	purine nucleotide binding
2.25	4.28e-02	GO:0004672	protein kinase activity
1.57	4.89e-02	GO:0000166	nucleotide binding