Motif ID: UAAUGCU

Z-value: 0.621


Mature miRNA associated with seed UAAUGCU:

NamemiRBase Accession
mmu-miR-155 MIMAT0000165



Activity profile for motif UAAUGCU.

activity profile for motif UAAUGCU


Sorted Z-values histogram for motif UAAUGCU

Sorted Z-values for motif UAAUGCU



Network of associatons between targets according to the STRING database.



First level regulatory network of UAAUGCU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_135728188 8.258 NM_177733
E2f2
E2F transcription factor 2
chr10_-_20880559 7.288 NM_001198914
NM_010848
Myb

myeloblastosis oncogene

chr1_+_9788206 7.102 NM_133220
NM_177547
Sgk3

serum/glucocorticoid regulated kinase 3

chr1_+_9838330 6.764 NM_001037759
Sgk3
serum/glucocorticoid regulated kinase 3
chr9_+_32503600 6.632 NM_001038642
NM_011808
Ets1

E26 avian leukemia oncogene 1, 5' domain

chr19_+_12535268 6.579 NM_010821
Mpeg1
macrophage expressed gene 1
chr2_-_160192799 6.008 NM_010658
Mafb
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)
chr13_+_44826121 5.338 NM_021878
Jarid2
jumonji, AT rich interactive domain 2
chr6_-_39156706 5.203 NM_001033430
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr15_-_66663390 5.180 NM_001029841
Sla
src-like adaptor
chr11_+_70246079 4.909 NM_145429
Arrb2
arrestin, beta 2
chr4_+_11083585 4.861 NM_021897
Trp53inp1
transformation related protein 53 inducible nuclear protein 1
chr5_-_141476549 4.856 NM_175362
Card11
caspase recruitment domain family, member 11
chr17_-_51971946 4.725 NM_009122
Satb1
special AT-rich sequence binding protein 1
chr11_-_46202942 4.692 NM_010583
Itk
IL2-inducible T-cell kinase
chr15_+_102236709 4.641 NM_013672
Sp1
trans-acting transcription factor 1
chr15_-_66644127 4.510 NM_009192
Sla
src-like adaptor
chr19_-_11340591 4.487 NM_007641
Ms4a1
membrane-spanning 4-domains, subfamily A, member 1
chr17_-_51951378 4.370 NM_001163630
Satb1
special AT-rich sequence binding protein 1
chr19_-_4397075 3.974 NM_001001984
Kdm2a
lysine (K)-specific demethylase 2A
chr17_-_51972514 3.889 NM_001163632
Satb1
special AT-rich sequence binding protein 1
chr1_+_89516886 3.833 NM_001110192
NM_001110193
NM_010566
Inpp5d


inositol polyphosphate-5-phosphatase D


chr16_+_87699143 3.665 NM_007520
Bach1
BTB and CNC homology 1
chr17_-_51965912 3.472 NM_001163631
Satb1
special AT-rich sequence binding protein 1
chr19_+_5637459 3.396 NM_009045
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr11_-_103128675 3.236 NM_016896
Map3k14
mitogen-activated protein kinase kinase kinase 14
chr15_+_96117952 3.098 NM_175251
Arid2
AT rich interactive domain 2 (ARID, RFX-like)
chr9_-_107980133 3.052 NM_032543
Rnf123
ring finger protein 123
chr19_+_29441927 3.004 NM_021893
Cd274
CD274 antigen
chr1_-_133176085 2.983 NM_019777
Ikbke
inhibitor of kappaB kinase epsilon
chr4_-_3865501 2.932 NM_019969
Plag1
pleiomorphic adenoma gene 1
chr3_-_19211000 2.919 NM_001122759
Pde7a
phosphodiesterase 7A
chr1_+_64579358 2.687 NM_001037726
NM_009952
NM_133828
Creb1


cAMP responsive element binding protein 1


chr8_+_28087807 2.643 NM_001101502
NM_001110508
Zfp703

zinc finger protein 703

chr5_-_66489416 2.601 NM_139065
Rbm47
RNA binding motif protein 47
chr15_-_27611236 2.548 NM_198301
Fam105a
family with sequence similarity 105, member A
chr13_+_75844906 2.494 NM_138953
Ell2
elongation factor RNA polymerase II 2
chr18_-_82862111 2.396 NM_177832
Zfp236
zinc finger protein 236
chr15_-_50721552 2.384 NM_032000
Trps1
trichorhinophalangeal syndrome I (human)
chr10_-_13043959 2.312 NM_001033257
NM_001195096
Phactr2

phosphatase and actin regulator 2

chr3_+_87329497 2.303 NM_001083318
NM_012051
Etv3

ets variant gene 3

chr2_+_131088210 2.281 NM_153501
Pank2
pantothenate kinase 2
chr5_-_66542161 2.281 NM_178446
Rbm47
RNA binding motif protein 47
chr4_+_97248556 2.260 NM_001122952
Nfia
D130039L10Rik
nuclear factor I/A
RIKEN cDNA D130039L10 gene
chr12_+_72116953 2.234 NM_001081195
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr5_-_66543123 2.216 NM_001127382
Rbm47
RNA binding motif protein 47
chr2_+_92024338 2.213 NM_138755
Phf21a
PHD finger protein 21A
chr3_-_19164956 2.149 NM_008802
Pde7a
phosphodiesterase 7A
chr18_+_61265225 2.136 NM_001037859
Csf1r
colony stimulating factor 1 receptor
chr10_-_13108775 2.090 NM_001195066
Phactr2
phosphatase and actin regulator 2
chr2_+_90936845 2.035 NM_011355
Sfpi1
SFFV proviral integration 1
chr5_+_142877419 1.998 NM_199068
Foxk1
forkhead box K1
chr2_-_90420626 1.994 NM_008982
Ptprj
protein tyrosine phosphatase, receptor type, J
chr7_+_90015842 1.981 NM_175366
Mex3b
mex3 homolog B (C. elegans)
chr7_+_97278722 1.956 NM_146194
Picalm
phosphatidylinositol binding clathrin assembly protein
chr10_-_13194201 1.940 NM_001195065
Phactr2
phosphatase and actin regulator 2
chr10_-_7675872 1.874 NM_138667
Tab2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr18_+_44540137 1.856 NM_027490
Dcp2
DCP2 decapping enzyme homolog (S. cerevisiae)
chr3_+_151873407 1.835 NM_057172
Fubp1
far upstream element (FUSE) binding protein 1
chr6_+_8459595 1.823 NM_133236
Glcci1
glucocorticoid induced transcript 1
chr19_-_14672472 1.800 NM_011600
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr9_+_107790457 1.793 NM_028369
Mon1a
MON1 homolog A (yeast)
chr1_+_193730645 1.757 NM_009579
Slc30a1
solute carrier family 30 (zinc transporter), member 1
chr10_+_79611013 1.756 NM_021565
Midn
midnolin
chr9_+_96159123 1.739 NM_001184709
Tfdp2
transcription factor Dp 2
chr2_-_72817311 1.700 NM_001098425
Sp3
trans-acting transcription factor 3
chr11_+_95610380 1.694 NM_201609
Zfp652
zinc finger protein 652
chr9_+_106270889 1.572 NM_153459
Dusp7
dual specificity phosphatase 7
chr1_+_61685397 1.562 NM_001081050
Pard3b
par-3 partitioning defective 3 homolog B (C. elegans)
chr11_-_5344795 1.544 NM_001080924
Znrf3
zinc and ring finger 3
chr4_-_66065499 1.458 NM_019514
NM_207109
Astn2

astrotactin 2

chr19_+_43764161 1.445 NM_053103
Entpd7
ectonucleoside triphosphate diphosphohydrolase 7
chr15_+_59480204 1.422 NM_144549
Trib1
tribbles homolog 1 (Drosophila)
chrX_-_71330931 1.401 NM_010788
NM_001081979
Mecp2

methyl CpG binding protein 2

chr2_+_92025639 1.377 NM_001109691
Phf21a
PHD finger protein 21A
chr12_+_33638809 1.358 NM_013635
Sypl
synaptophysin-like protein
chr13_+_112476313 1.358 NM_172593
Mier3
mesoderm induction early response 1, family member 3
chr3_-_115417932 1.356 NM_007901
S1pr1
sphingosine-1-phosphate receptor 1
chr2_-_103143352 1.345 NM_007914
Ehf
ets homologous factor
chr7_-_85992096 1.323 NM_029585
Det1
de-etiolated homolog 1 (Arabidopsis)
chr2_-_72818502 1.319 NM_001018042
Sp3
trans-acting transcription factor 3
chr1_+_179374783 1.276 NM_001012330
Zfp238
zinc finger protein 238
chr17_+_26852581 1.248 NM_029870
A930001N09Rik
RIKEN cDNA A930001N09 gene
chr13_+_83643032 1.209 NM_001170537
NM_025282
Mef2c

myocyte enhancer factor 2C

chr4_+_97444312 1.189 NM_001122953
NM_010905
Nfia

nuclear factor I/A

chr1_+_60965868 1.188 NM_009843
Ctla4
cytotoxic T-lymphocyte-associated protein 4
chr17_+_87362450 1.185 NM_145491
Rhoq
ras homolog gene family, member Q
chr12_+_33639034 1.184 NM_198710
Sypl
synaptophysin-like protein
chr5_-_36826896 1.165 NM_001170454
Tada2b
transcriptional adaptor 2B
chr19_+_40969176 1.148 NM_028319
E130314M14Rik
Zfp518a
RIKEN cDNA E130314M14 gene
zinc finger protein 518A
chr11_-_103273956 1.136 NM_183034
Plekhm1
pleckstrin homology domain containing, family M (with RUN domain) member 1
chr4_+_6292817 1.132 NM_001098227
NM_016807
Sdcbp

syndecan binding protein

chr8_-_82581887 1.126 NM_020259
Hhip
Hedgehog-interacting protein
chr11_-_86621130 1.114 NM_026191
Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr6_+_122503826 1.090 NM_009645
Aicda
activation-induced cytidine deaminase
chr12_-_60320438 1.063 NM_001033156
Fbxo33
F-box protein 33
chr14_-_40286236 1.063 NM_001190187
NM_001190188
NM_008734
Nrg3


neuregulin 3


chr18_-_67884185 1.060 NM_001127177
NM_008977
Ptpn2

protein tyrosine phosphatase, non-receptor type 2

chr2_+_75497282 1.056 NM_053263
NM_146130
NM_198090
Hnrnpa3


Gm6793
heterogeneous nuclear ribonucleoprotein A3


heterogeneous nuclear ribonucleoprotein A3 pseudogene
chr8_-_89409079 1.037 NM_030563
N4bp1
NEDD4 binding protein 1
chr11_-_104303565 1.018 NM_001081045
1700081L11Rik
RIKEN cDNA 1700081L11 gene
chr6_-_145198693 1.003 NM_021284
Kras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
chr11_+_93747419 1.002 NM_134012
Mbtd1
mbt domain containing 1
chr11_+_87881747 0.990 NM_016686
Vezf1
vascular endothelial zinc finger 1
chr3_-_37131486 0.968 NM_021782
Il21
interleukin 21
chr18_-_89063572 0.961 NM_018821
Socs6
suppressor of cytokine signaling 6
chr12_+_112404645 0.951 NM_001048206
NM_011632
Traf3

TNF receptor-associated factor 3

chr11_+_20443168 0.945 NM_021372
Sertad2
SERTA domain containing 2
chr16_+_94085504 0.943 NM_011377
Sim2
single-minded homolog 2 (Drosophila)
chr15_-_88564636 0.939 NM_001033274
Brd1
bromodomain containing 1
chr19_+_46697882 0.933 NM_001177813
D19Wsu162e
DNA segment, Chr 19, Wayne State University 162, expressed
chr7_-_54263783 0.930 NM_175318
Spty2d1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr11_+_77499638 0.922 NM_001024205
Nufip2
nuclear fragile X mental retardation protein interacting protein 2
chr9_+_96096690 0.920 NM_001184706
NM_001184708
NM_178667
Tfdp2


transcription factor Dp 2


chr19_+_46673553 0.915 NM_001177812
NM_146099
D19Wsu162e

DNA segment, Chr 19, Wayne State University 162, expressed

chr3_-_68930928 0.902 NM_008467
Kpna4
karyopherin (importin) alpha 4
chr1_+_179375951 0.843 NM_013915
Zfp238
zinc finger protein 238
chr4_+_98062481 0.814 NM_001005784
NM_172696
Inadl

InaD-like (Drosophila)

chr12_+_66137309 0.792 NM_177806
Prpf39
PRP39 pre-mRNA processing factor 39 homolog (yeast)
chr5_-_68238654 0.791 NM_001038999
NM_009727
Atp8a1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr15_+_80541675 0.791 NM_144812
Tnrc6b
trinucleotide repeat containing 6b
chr13_+_37980739 0.776 NM_001177869
Rreb1
ras responsive element binding protein 1
chr2_+_173902521 0.767 NM_001102423
NM_001102424
NM_001102425
NM_172675
Stx16



syntaxin 16



chr10_+_57857120 0.763 NM_001193303
Lims1
LIM and senescent cell antigen-like domains 1
chr10_+_87321789 0.761 NM_001111275
NM_010512
Igf1

insulin-like growth factor 1

chr10_+_57786213 0.750 NM_026148
Lims1
LIM and senescent cell antigen-like domains 1
chr6_+_29809595 0.750 NM_001171001
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr19_+_53218486 0.749 NM_013758
Add3
adducin 3 (gamma)
chr9_-_70351520 0.748 NM_033604
Rnf111
ring finger 111
chr16_-_21694608 0.745 NM_001001881
2510009E07Rik
RIKEN cDNA 2510009E07 gene
chr10_-_29082247 0.742 NM_001110196
NM_001110197
NM_001110198
NM_026518
Rnf146



ring finger protein 146



chr8_-_25549415 0.738 NM_026931
1810011O10Rik
RIKEN cDNA 1810011O10 gene
chr7_-_127039189 0.736 NM_001163703
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr1_-_182743632 0.735 NM_008210
H3f3a
H3 histone, family 3A
chr8_-_129117310 0.727 NM_001164598
Irf2bp2
interferon regulatory factor 2 binding protein 2
chr16_-_91044623 0.724 NM_026110
Gcfc1
GC-rich sequence DNA-binding factor 1
chr7_-_127038916 0.699 NM_173408
Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr7_-_123182257 0.691 NM_001025559
Sox6
SRY-box containing gene 6
chr3_+_61168428 0.686 NM_028712
Rap2b
RAP2B, member of RAS oncogene family
chr10_+_13686174 0.665 NM_010437
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr19_-_21547072 0.659 NM_010266
Gda
guanine deaminase
chr1_+_87690003 0.645 NM_133781
Cab39
calcium binding protein 39
chr11_+_20991321 0.642 NM_023324
Peli1
pellino 1
chr8_-_112261607 0.636 NM_001080930
Atxn1l
ataxin 1-like
chr9_+_21420612 0.632 NM_001174078
NM_001174079
NM_011417
Smarca4


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4


chr8_+_108424267 0.623 NM_173432
Pskh1
protein serine kinase H1
chr19_-_41338400 0.610 NM_133352
Tm9sf3
transmembrane 9 superfamily member 3
chr3_-_142544883 0.602 NM_178654
Pkn2
protein kinase N2
chr1_+_135260143 0.588 NM_175443
Etnk2
ethanolamine kinase 2
chr18_-_84758848 0.587 NM_001033341
Zfp407
zinc finger protein 407
chr15_+_80629020 0.586 NM_177124
Tnrc6b
trinucleotide repeat containing 6b
chrX_+_19941606 0.582 NM_133669
Rp2h
retinitis pigmentosa 2 homolog (human)
chr16_+_45158927 0.581 NM_026402
Atg3
autophagy-related 3 (yeast)
chr4_+_137150067 0.579 NM_130879
Usp48
ubiquitin specific peptidase 48
chr5_-_9161670 0.570 NM_001110327
NM_011806
Dmtf1

cyclin D binding myb-like transcription factor 1

chr15_+_6658368 0.566 NM_030168
Rictor
RPTOR independent companion of MTOR, complex 2
chrX_+_45694534 0.563 NM_178782
Bcorl1
BCL6 co-repressor-like 1
chr19_+_53217238 0.552 NM_001164100
Add3
adducin 3 (gamma)
chr13_+_91600662 0.531 NM_024186
NM_024272
Ssbp2

single-stranded DNA binding protein 2

chr19_-_60656627 0.525 NM_001172096
NM_001172097
NM_030197
2700078E11Rik


RIKEN cDNA 2700078E11 gene


chr4_-_154596628 0.516 NM_011385
Ski
ski sarcoma viral oncogene homolog (avian)
chr11_+_20531941 0.515 NM_001038625
Sertad2
SERTA domain containing 2
chr9_+_121551833 0.508 NM_011703
Vipr1
vasoactive intestinal peptide receptor 1
chr19_+_55969810 0.502 NM_001142924
Tcf7l2
transcription factor 7-like 2, T-cell specific, HMG-box
chr19_+_55816299 0.489 NM_001142918
NM_001142919
NM_001142920
NM_001142921
NM_001142922
NM_001142923
NM_009333
Tcf7l2






transcription factor 7-like 2, T-cell specific, HMG-box






chr5_-_28793627 0.479 NM_009170
Shh
sonic hedgehog
chr6_-_119988624 0.477 NM_001185020
NM_001185021
NM_198703
Wnk1


WNK lysine deficient protein kinase 1


chr12_-_101963226 0.472 NM_153587
Rps6ka5
ribosomal protein S6 kinase, polypeptide 5
chr4_-_147462051 0.470 NM_009642
Agtrap
angiotensin II, type I receptor-associated protein
chr18_+_61715202 0.466 NM_146087
Csnk1a1
casein kinase 1, alpha 1
chr1_-_39634096 0.461 NM_001033135
Rnf149
ring finger protein 149
chr2_+_92061718 0.453 NM_001109690
Phf21a
PHD finger protein 21A
chr9_+_70526702 0.437 NM_007399
Adam10
a disintegrin and metallopeptidase domain 10
chr6_+_115881925 0.429 NM_145383
Rho
rhodopsin
chr10_+_57834201 0.427 NM_201242
Lims1
LIM and senescent cell antigen-like domains 1
chr8_+_121918768 0.424 NM_019966
Mlycd
malonyl-CoA decarboxylase
chr8_+_109817355 0.423 NM_018823
NM_133957
Nfat5

nuclear factor of activated T-cells 5

chr13_+_56804370 0.418 NM_008541
NM_001164041
Smad5

MAD homolog 5 (Drosophila)

chr2_-_75542552 0.413 NM_010902
Nfe2l2
nuclear factor, erythroid derived 2, like 2
chr3_+_41367304 0.399 NM_172303
Phf17
PHD finger protein 17
chr4_+_21703416 0.386 NM_152825
Usp45
ubiquitin specific petidase 45
chr2_-_163896796 0.382 NM_025996
Tomm34
translocase of outer mitochondrial membrane 34
chr2_-_60560659 0.376 NM_001159564
Itgb6
integrin beta 6
chr5_-_73647856 0.370 NM_028194
Fryl
furry homolog-like (Drosophila)
chr3_+_89324085 0.369 NM_080466
Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr3_+_41367672 0.368 NM_001130185
Phf17
PHD finger protein 17
chr19_+_6276885 0.358 NM_010119
Ehd1
EH-domain containing 1
chr4_+_43591606 0.349 NM_172866
Rgp1
RGP1 retrograde golgi transport homolog (S. cerevisiae)
chr6_-_88396477 0.335 NM_023060
Eefsec
eukaryotic elongation factor, selenocysteine-tRNA-specific
chr19_+_6047024 0.326 NM_001164709
Syvn1
synovial apoptosis inhibitor 1, synoviolin
chr13_-_12554004 0.312 NM_001199043
NM_018886
Lgals8

lectin, galactose binding, soluble 8

chr14_+_57506630 0.302 NM_029498
Zmym2
zinc finger, MYM-type 2
chr5_+_93522440 0.301 NM_001009818
Sept11
septin 11
chr12_-_52792851 0.299 NM_001172098
NM_052973
Strn3

striatin, calmodulin binding protein 3

chr7_-_74517624 0.299 NM_001033713
Mef2a
myocyte enhancer factor 2A
chr7_-_123174560 0.297 NM_001025560
Sox6
SRY-box containing gene 6
chr9_+_7628229 0.296 NM_013903
Mmp20
matrix metallopeptidase 20 (enamelysin)
chr3_+_41368801 0.273 NM_001130186
Phf17
PHD finger protein 17
chr19_+_53214934 0.271 NM_001164099
NM_001164101
Add3

adducin 3 (gamma)

chr9_+_96159666 0.262 NM_001184710
NM_001184711
Tfdp2

transcription factor Dp 2


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.30 7.75e-18 GO:0006355 regulation of transcription, DNA-dependent
3.13 1.02e-17 GO:0010556 regulation of macromolecule biosynthetic process
3.24 2.40e-17 GO:0051252 regulation of RNA metabolic process
2.66 3.74e-17 GO:0031323 regulation of cellular metabolic process
3.12 4.86e-17 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.95 2.77e-16 GO:0031326 regulation of cellular biosynthetic process
2.99 2.91e-16 GO:0010468 regulation of gene expression
2.92 5.81e-16 GO:0009889 regulation of biosynthetic process
2.65 6.46e-16 GO:0060255 regulation of macromolecule metabolic process
2.59 1.48e-15 GO:0080090 regulation of primary metabolic process
2.90 3.35e-15 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.86 6.02e-15 GO:0051171 regulation of nitrogen compound metabolic process
3.52 1.15e-14 GO:0006351 transcription, DNA-dependent
3.51 1.25e-14 GO:0032774 RNA biosynthetic process
2.38 3.55e-14 GO:0019222 regulation of metabolic process
2.21 1.25e-13 GO:0044260 cellular macromolecule metabolic process
2.85 6.38e-12 GO:0016070 RNA metabolic process
2.03 1.39e-11 GO:0043170 macromolecule metabolic process
1.86 3.39e-11 GO:0044237 cellular metabolic process
2.65 1.21e-10 GO:0010467 gene expression
2.65 9.54e-10 GO:0034645 cellular macromolecule biosynthetic process
2.63 1.36e-09 GO:0009059 macromolecule biosynthetic process
2.48 3.74e-09 GO:0090304 nucleic acid metabolic process
4.30 6.67e-09 GO:0051254 positive regulation of RNA metabolic process
2.29 9.00e-09 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.22 2.35e-08 GO:0045893 positive regulation of transcription, DNA-dependent
4.00 4.03e-08 GO:0010628 positive regulation of gene expression
1.66 4.22e-08 GO:0008152 metabolic process
3.87 4.44e-08 GO:0010557 positive regulation of macromolecule biosynthetic process
3.25 4.94e-08 GO:0010604 positive regulation of macromolecule metabolic process
3.71 6.30e-08 GO:0031328 positive regulation of cellular biosynthetic process
1.73 6.62e-08 GO:0044238 primary metabolic process
3.19 8.59e-08 GO:0031325 positive regulation of cellular metabolic process
3.65 9.96e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.13 1.03e-07 GO:0034641 cellular nitrogen compound metabolic process
3.64 1.05e-07 GO:0009891 positive regulation of biosynthetic process
2.24 1.15e-07 GO:0044249 cellular biosynthetic process
3.81 1.43e-07 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.07 1.46e-07 GO:0009893 positive regulation of metabolic process
1.60 2.22e-07 GO:0050794 regulation of cellular process
3.71 2.64e-07 GO:0051173 positive regulation of nitrogen compound metabolic process
2.08 3.40e-07 GO:0006807 nitrogen compound metabolic process
2.18 3.99e-07 GO:0009058 biosynthetic process
13.62 4.83e-07 GO:0002224 toll-like receptor signaling pathway
12.69 1.05e-06 GO:0002221 pattern recognition receptor signaling pathway
12.41 1.34e-06 GO:0002758 innate immune response-activating signal transduction
9.36 1.43e-06 GO:0045088 regulation of innate immune response
12.14 1.70e-06 GO:0002218 activation of innate immune response
1.54 1.72e-06 GO:0050789 regulation of biological process
2.46 1.85e-06 GO:0048523 negative regulation of cellular process
10.33 2.02e-06 GO:0045089 positive regulation of innate immune response
3.48 2.39e-06 GO:0002376 immune system process
4.23 2.65e-06 GO:0002682 regulation of immune system process
2.22 2.92e-06 GO:0048518 positive regulation of biological process
4.96 4.45e-06 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
14.28 1.25e-05 GO:0002756 MyD88-independent toll-like receptor signaling pathway
2.29 1.34e-05 GO:0048519 negative regulation of biological process
8.71 1.43e-05 GO:0002757 immune response-activating signal transduction
4.01 1.62e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.49 1.66e-05 GO:0065007 biological regulation
3.70 1.76e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
8.46 1.96e-05 GO:0002764 immune response-regulating signaling pathway
3.95 2.15e-05 GO:0051253 negative regulation of RNA metabolic process
3.77 2.50e-05 GO:0010629 negative regulation of gene expression
13.06 2.81e-05 GO:0002755 MyD88-dependent toll-like receptor signaling pathway
2.20 3.19e-05 GO:0048522 positive regulation of cellular process
3.17 3.67e-05 GO:0010605 negative regulation of macromolecule metabolic process
3.50 5.31e-05 GO:0009890 negative regulation of biosynthetic process
3.47 6.22e-05 GO:0048584 positive regulation of response to stimulus
7.57 6.82e-05 GO:0031349 positive regulation of defense response
3.90 1.12e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.59 1.20e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
7.13 1.32e-04 GO:0002253 activation of immune response
3.44 1.38e-04 GO:0031327 negative regulation of cellular biosynthetic process
3.55 1.49e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
3.54 1.58e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
4.96 1.69e-04 GO:0050776 regulation of immune response
2.93 1.99e-04 GO:0009892 negative regulation of metabolic process
4.48 2.92e-04 GO:0002684 positive regulation of immune system process
5.87 3.77e-04 GO:0043193 positive regulation of gene-specific transcription
2.96 4.33e-04 GO:0031324 negative regulation of cellular metabolic process
2.43 5.51e-04 GO:0048583 regulation of response to stimulus
5.35 1.08e-03 GO:0050778 positive regulation of immune response
6.21 1.76e-03 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
4.15 1.79e-03 GO:0032583 regulation of gene-specific transcription
4.95 2.57e-03 GO:0031347 regulation of defense response
1.28 2.79e-03 GO:0009987 cellular process
5.04 5.25e-03 GO:0051101 regulation of DNA binding
2.20 5.39e-03 GO:0048513 organ development
2.23 8.01e-03 GO:0006464 protein modification process
11.95 1.06e-02 GO:0030218 erythrocyte differentiation
4.25 1.34e-02 GO:0051098 regulation of binding
1.78 1.38e-02 GO:0032502 developmental process
15.38 1.69e-02 GO:0051897 positive regulation of protein kinase B signaling cascade
4.14 1.75e-02 GO:0016568 chromatin modification
3.85 1.90e-02 GO:0009968 negative regulation of signal transduction
2.12 2.23e-02 GO:0043412 macromolecule modification
10.33 2.50e-02 GO:0034101 erythrocyte homeostasis
3.99 2.58e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.95 2.68e-02 GO:0044267 cellular protein metabolic process
1.79 2.78e-02 GO:0007275 multicellular organismal development
3.86 3.62e-02 GO:0002520 immune system development
4.44 4.24e-02 GO:0061061 muscle structure development
2.60 4.25e-02 GO:0042127 regulation of cell proliferation
9.37 4.36e-02 GO:0048863 stem cell differentiation
3.52 4.97e-02 GO:0023057 negative regulation of signaling

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.23 8.14e-17 GO:0005634 nucleus
1.48 9.23e-11 GO:0044424 intracellular part
1.45 7.17e-10 GO:0005622 intracellular
4.37 5.92e-09 GO:0044451 nucleoplasm part
1.58 1.13e-08 GO:0043231 intracellular membrane-bounded organelle
1.58 1.32e-08 GO:0043227 membrane-bounded organelle
3.01 1.63e-08 GO:0031981 nuclear lumen
3.47 4.04e-08 GO:0005654 nucleoplasm
2.70 5.93e-08 GO:0044428 nuclear part
2.68 3.39e-07 GO:0070013 intracellular organelle lumen
2.67 3.58e-07 GO:0043233 organelle lumen
1.47 4.43e-07 GO:0043229 intracellular organelle
1.47 5.46e-07 GO:0043226 organelle
2.62 6.54e-07 GO:0031974 membrane-enclosed lumen
4.66 2.35e-04 GO:0005667 transcription factor complex
1.18 9.70e-04 GO:0005623 cell
1.18 9.70e-04 GO:0044464 cell part
7.33 5.55e-03 GO:0000790 nuclear chromatin
1.77 7.18e-03 GO:0043234 protein complex
1.57 1.37e-02 GO:0044446 intracellular organelle part
1.65 1.61e-02 GO:0032991 macromolecular complex
1.54 2.37e-02 GO:0044422 organelle part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.51 6.99e-12 GO:0005488 binding
4.44 1.90e-10 GO:0001071 nucleic acid binding transcription factor activity
4.44 1.90e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
3.94 1.00e-09 GO:0030528 transcription regulator activity
2.70 8.59e-08 GO:0003677 DNA binding
2.96 1.98e-07 GO:0008270 zinc ion binding
2.27 4.25e-07 GO:0003676 nucleic acid binding
1.68 4.08e-06 GO:0005515 protein binding
5.23 4.83e-06 GO:0016563 transcription activator activity
2.54 8.38e-06 GO:0046914 transition metal ion binding
5.19 1.39e-05 GO:0016564 transcription repressor activity
3.37 1.91e-04 GO:0043565 sequence-specific DNA binding
4.60 3.82e-04 GO:0008134 transcription factor binding
1.80 4.88e-04 GO:0043167 ion binding
1.79 6.58e-04 GO:0046872 metal ion binding
1.77 9.48e-04 GO:0043169 cation binding
2.84 1.04e-03 GO:0019899 enzyme binding
4.86 1.19e-03 GO:0019901 protein kinase binding
4.40 1.43e-03 GO:0019900 kinase binding
4.51 2.98e-02 GO:0003682 chromatin binding
7.17 3.07e-02 GO:0031625 ubiquitin protein ligase binding