Motif ID: UCACAGU

Z-value: 0.566


Mature miRNA associated with seed UCACAGU:

NamemiRBase Accession
mmu-miR-27a MIMAT0000537
mmu-miR-27b MIMAT0000126



Activity profile for motif UCACAGU.

activity profile for motif UCACAGU


Sorted Z-values histogram for motif UCACAGU

Sorted Z-values for motif UCACAGU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCACAGU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_33623069 5.659 NM_001109990
 D0H4S114
DNA segment, human D4S114
chr18_-_33623287 5.524 NM_053078
 D0H4S114
DNA segment, human D4S114
chr7_+_121558695 5.314 NM_011055
 Pde3b
phosphodiesterase 3B, cGMP-inhibited
chr18_-_33623400 5.114 NM_001109989
 D0H4S114
DNA segment, human D4S114
chr5_-_107718503 5.047 NM_011578
 Tgfbr3
transforming growth factor, beta receptor III
chr18_-_33623668 5.047 NM_001109988
 D0H4S114
DNA segment, human D4S114
chr2_+_167906462 4.536 NM_021409
 Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr9_+_72510153 4.482 NM_010890
 Nedd4
neural precursor cell expressed, developmentally down-regulated 4
chr16_+_33684551 4.321 NM_175256
 Heg1
HEG homolog 1 (zebrafish)
chr10_-_53795556 4.094 NM_008548
 Man1a
mannosidase 1, alpha
chr8_-_25549415 3.895 NM_026931
 1810011O10Rik
RIKEN cDNA 1810011O10 gene
chr3_+_52072251 3.699 NM_019739
 Foxo1
forkhead box O1
chr1_-_82287990 3.691 NM_010570
 Irs1
insulin receptor substrate 1
chr16_+_44173356 3.467 NM_001029889
 Gm608
predicted gene 608
chr15_-_98438063 3.456 NM_007405
 Adcy6
adenylate cyclase 6
chr3_-_129035406 3.442 NM_007934
 Enpep
glutamyl aminopeptidase
chrX_+_104451216 3.304 NM_001177781
NM_001033251
 Gpr174

G protein-coupled receptor 174

chr5_-_21850490 3.198 NM_011261
 Reln
reelin
chr8_+_24521967 3.101 NM_013834
 Sfrp1
secreted frizzled-related protein 1
chr12_-_16596573 3.017 NM_001130412
NM_015763
NM_172950
 Lpin1


lipin 1



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 143 entries
Enrichment   P-value GO Accession GO Term
39.77 2.63e-02 GO:0090245 axis elongation involved in somitogenesis
10.71 4.38e-03 GO:0018210 peptidyl-threonine modification
7.31 5.19e-03 GO:0043401 steroid hormone mediated signaling pathway
6.03 9.10e-03 GO:0032869 cellular response to insulin stimulus
5.85 1.20e-02 GO:0071383 cellular response to steroid hormone stimulus
4.81 2.90e-02 GO:0032868 response to insulin stimulus
4.66 3.95e-02 GO:2000027 regulation of organ morphogenesis
4.08 1.86e-04 GO:0032870 cellular response to hormone stimulus
4.08 3.45e-03 GO:0050678 regulation of epithelial cell proliferation
3.94 1.63e-04 GO:0071495 cellular response to endogenous stimulus
3.76 5.21e-03 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
3.71 1.07e-12 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.47 4.26e-15 GO:0051254 positive regulation of RNA metabolic process
3.47 8.31e-15 GO:0045893 positive regulation of transcription, DNA-dependent
3.36 7.35e-03 GO:0043193 positive regulation of gene-specific transcription
3.32 3.09e-05 GO:0007167 enzyme linked receptor protein signaling pathway
3.29 4.78e-17 GO:0006357 regulation of transcription from RNA polymerase II promoter
3.29 3.76e-14 GO:0010628 positive regulation of gene expression
3.28 1.12e-03 GO:0018193 peptidyl-amino acid modification
3.25 1.49e-04 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
Enrichment   P-value GO Accession GO Term
2.87 2.49e-03 GO:0005667 transcription factor complex
2.81 7.04e-08 GO:0044451 nucleoplasm part
2.25 1.97e-02 GO:0045202 synapse
2.18 1.98e-05 GO:0005654 nucleoplasm
1.93 4.01e-05 GO:0031981 nuclear lumen
1.77 3.90e-04 GO:0070013 intracellular organelle lumen
1.77 4.17e-04 GO:0043233 organelle lumen
1.76 2.27e-04 GO:0044428 nuclear part
1.76 4.40e-04 GO:0031974 membrane-enclosed lumen
1.66 8.47e-13 GO:0005634 nucleus
1.45 2.51e-02 GO:0043234 protein complex
1.40 1.01e-10 GO:0043231 intracellular membrane-bounded organelle
1.40 1.33e-10 GO:0043227 membrane-bounded organelle
1.37 9.76e-03 GO:0044422 organelle part
1.36 1.42e-02 GO:0044446 intracellular organelle part
1.35 1.82e-14 GO:0005622 intracellular
1.35 3.69e-14 GO:0044424 intracellular part
1.35 9.22e-10 GO:0043229 intracellular organelle
1.34 1.37e-09 GO:0043226 organelle
1.31 4.26e-06 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 20 of 37 entries
Enrichment   P-value GO Accession GO Term
7.96 3.14e-02 GO:0035591 signaling adaptor activity
7.16 1.34e-03 GO:0003707 steroid hormone receptor activity
7.02 1.59e-03 GO:0004879 ligand-dependent nuclear receptor activity
5.45 4.97e-03 GO:0019199 transmembrane receptor protein kinase activity
4.77 3.86e-02 GO:0060090 binding, bridging
3.37 8.49e-04 GO:0003712 transcription cofactor activity
3.36 9.06e-04 GO:0000989 transcription factor binding transcription factor activity
3.32 1.10e-03 GO:0000988 protein binding transcription factor activity
3.26 3.04e-05 GO:0016563 transcription activator activity
3.23 1.45e-02 GO:0010843 promoter binding
3.10 1.15e-11 GO:0001071 nucleic acid binding transcription factor activity
3.10 1.15e-11 GO:0003700 sequence-specific DNA binding transcription factor activity
3.09 4.06e-04 GO:0008134 transcription factor binding
3.03 3.11e-02 GO:0000975 regulatory region DNA binding
3.03 3.11e-02 GO:0001067 regulatory region nucleic acid binding
3.03 3.11e-02 GO:0044212 transcription regulatory region DNA binding
2.85 2.52e-02 GO:0019901 protein kinase binding
2.83 2.18e-06 GO:0004672 protein kinase activity
2.77 4.34e-07 GO:0043565 sequence-specific DNA binding
2.77 4.92e-04 GO:0004674 protein serine/threonine kinase activity