Motif ID: UCACAGU

Z-value: 0.566


Mature miRNA associated with seed UCACAGU:

NamemiRBase Accession
mmu-miR-27a MIMAT0000537
mmu-miR-27b MIMAT0000126



Activity profile for motif UCACAGU.

activity profile for motif UCACAGU


Sorted Z-values histogram for motif UCACAGU

Sorted Z-values for motif UCACAGU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCACAGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_33623069 5.659 NM_001109990
D0H4S114
DNA segment, human D4S114
chr18_-_33623287 5.524 NM_053078
D0H4S114
DNA segment, human D4S114
chr7_+_121558695 5.314 NM_011055
Pde3b
phosphodiesterase 3B, cGMP-inhibited
chr18_-_33623400 5.114 NM_001109989
D0H4S114
DNA segment, human D4S114
chr5_-_107718503 5.047 NM_011578
Tgfbr3
transforming growth factor, beta receptor III
chr18_-_33623668 5.047 NM_001109988
D0H4S114
DNA segment, human D4S114
chr2_+_167906462 4.536 NM_021409
Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr9_+_72510153 4.482 NM_010890
Nedd4
neural precursor cell expressed, developmentally down-regulated 4
chr16_+_33684551 4.321 NM_175256
Heg1
HEG homolog 1 (zebrafish)
chr10_-_53795556 4.094 NM_008548
Man1a
mannosidase 1, alpha
chr8_-_25549415 3.895 NM_026931
1810011O10Rik
RIKEN cDNA 1810011O10 gene
chr3_+_52072251 3.699 NM_019739
Foxo1
forkhead box O1
chr1_-_82287990 3.691 NM_010570
Irs1
insulin receptor substrate 1
chr16_+_44173356 3.467 NM_001029889
Gm608
predicted gene 608
chr15_-_98438063 3.456 NM_007405
Adcy6
adenylate cyclase 6
chr3_-_129035406 3.442 NM_007934
Enpep
glutamyl aminopeptidase
chrX_+_104451216 3.304 NM_001177781
NM_001033251
Gpr174

G protein-coupled receptor 174

chr5_-_21850490 3.198 NM_011261
Reln
reelin
chr8_+_24521967 3.101 NM_013834
Sfrp1
secreted frizzled-related protein 1
chr12_-_16596573 3.017 NM_001130412
NM_015763
NM_172950
Lpin1


lipin 1


chr9_+_65478364 2.968 NM_028030
Rbpms2
RNA binding protein with multiple splicing 2
chr17_-_80114299 2.927 NM_009994
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
chr15_+_85565935 2.907 NM_001113418
Ppara
peroxisome proliferator activated receptor alpha
chr1_-_135975681 2.907 NM_007570
Btg2
B-cell translocation gene 2, anti-proliferative
chr1_+_153602492 2.896 NM_001039644
Edem3
ER degradation enhancer, mannosidase alpha-like 3
chrX_+_104479684 2.864 NM_001177782
Gpr174
G protein-coupled receptor 174
chr4_-_57314708 2.790 NM_011207
Ptpn3
protein tyrosine phosphatase, non-receptor type 3
chr15_+_85566122 2.745 NM_011144
Ppara
peroxisome proliferator activated receptor alpha
chr16_-_46010510 2.691 NM_001134480
Plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr4_-_104782444 2.651 NM_178143
Prkaa2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr15_+_54402914 2.615 NM_178920
Mal2
mal, T-cell differentiation protein 2
chr3_+_52845429 2.564 NM_175386
Lhfp
lipoma HMGIC fusion partner
chr5_-_108416027 2.522 NM_026062
Fam69a
family with sequence similarity 69, member A
chr9_+_95459990 2.505 NM_198414
Paqr9
progestin and adipoQ receptor family member IX
chr11_+_49607656 2.499 NM_013529
Gfpt2
glutamine fructose-6-phosphate transaminase 2
chr16_+_90386629 2.497 NM_015755
Hunk
hormonally upregulated Neu-associated kinase
chr13_-_34437042 2.465 NM_001033167
Slc22a23
solute carrier family 22, member 23
chr4_-_131631226 2.452 NM_001128607
Epb4.1
erythrocyte protein band 4.1
chr12_-_27100112 2.450 NM_001081977
NM_080563
Rnf144a

ring finger protein 144A

chr16_+_11066390 2.434 NM_009223
Snn
stannin
chrX_+_135448968 2.430 NM_013724
Nrk
Nik related kinase
chr17_+_25325344 2.426 NM_001197024
Unkl
unkempt-like (Drosophila)
chr4_-_131604821 2.345 NM_001128606
Epb4.1
erythrocyte protein band 4.1
chr15_+_7090525 2.254 NM_013584
Lifr
leukemia inhibitory factor receptor
chr13_+_30841105 2.241 NM_013674
Irf4
interferon regulatory factor 4
chr11_+_90110701 2.212 NM_026178
Mmd
monocyte to macrophage differentiation-associated
chr1_+_19202046 2.185 NM_001025305
Tcfap2b
transcription factor AP-2 beta
chrX_+_69208336 2.180 NM_001081135
Prrg3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr17_+_4995073 2.159 NM_001085355
Arid1b
AT rich interactive domain 1B (SWI-like)
chr9_-_58884114 2.136 NM_001042752
NM_008684
Neo1

neogenin

chr17_+_26852581 2.101 NM_029870
A930001N09Rik
RIKEN cDNA A930001N09 gene
chr17_-_31992708 2.085 NM_010831
Sik1
salt inducible kinase 1
chr19_-_34952377 2.040 NM_023792
Pank1
pantothenate kinase 1
chr11_+_53164267 2.022 NM_033565
Aff4
AF4/FMR2 family, member 4
chr2_+_179777187 1.984 NM_178750
Ss18l1
synovial sarcoma translocation gene on chromosome 18-like 1
chr13_+_55311142 1.983 NM_008739
Nsd1
nuclear receptor-binding SET-domain protein 1
chr14_+_73637697 1.980 NM_175116
Lpar6
lysophosphatidic acid receptor 6
chr5_+_75552144 1.960 NM_001083316
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr8_+_106625524 1.951 NM_009868
Cdh5
cadherin 5
chr9_-_43047862 1.943 NM_178644
Oaf
OAF homolog (Drosophila)
chr6_+_34659440 1.934 NM_145575
Cald1
caldesmon 1
chr2_-_32306938 1.908 NM_001164357
NM_146118
Slc25a25

solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25

chrX_+_82819294 1.888 NM_025729
Tab3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr11_-_86807216 1.887 NM_001005341
Ypel2
yippee-like 2 (Drosophila)
chr17_+_14416508 1.885 NM_022315
Smoc2
SPARC related modular calcium binding 2
chr5_+_73882264 1.875 NM_001190733
NM_178896
Dcun1d4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chr6_+_17413930 1.822 NM_008591
Met
met proto-oncogene
chr18_-_34166859 1.817 NM_013512
Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr2_-_103143352 1.798 NM_007914
Ehf
ets homologous factor
chr16_-_4789869 1.788 NM_025670
5730403B10Rik
RIKEN cDNA 5730403B10 gene
chrX_-_130696466 1.745 NM_183319
Xkrx
X Kell blood group precursor related X linked
chr7_+_119822831 1.727 NM_001166584
NM_009346
Tead1

TEA domain family member 1

chr2_-_9800211 1.723 NM_008091
Gata3
GATA binding protein 3
chr17_+_25359526 1.715 NM_028789
Unkl
unkempt-like (Drosophila)
chr11_-_74983756 1.711 NM_010430
Hic1
hypermethylated in cancer 1
chr4_+_137418151 1.708 NM_199307
Ece1
endothelin converting enzyme 1
chr16_-_44028057 1.708 NM_001172107
Gramd1c
GRAM domain containing 1C
chr4_-_106850812 1.706 NM_025617
2210012G02Rik
RIKEN cDNA 2210012G02 gene
chr5_+_36235967 1.688 NM_027373
Afap1
actin filament associated protein 1
chr5_+_151476361 1.687 NM_175310
Pds5b
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr7_+_89484203 1.677 NM_001190374
Adamtsl3
ADAMTS-like 3
chr4_+_62876389 1.656 NM_025685
Col27a1
collagen, type XXVII, alpha 1
chr3_-_86978431 1.650 NM_001170985
NM_130867
Kirrel

kin of IRRE like (Drosophila)

chr3_+_9250566 1.623 NM_177660
Zbtb10
zinc finger and BTB domain containing 10
chr17_+_74154180 1.616 NM_020578
Ehd3
EH-domain containing 3
chr4_+_97444312 1.601 NM_001122953
NM_010905
Nfia

nuclear factor I/A

chr2_+_27532692 1.600 NM_011305
Rxra
retinoid X receptor alpha
chr7_-_77505248 1.588 NM_009697
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr1_+_162836541 1.586 NM_001024952
Rc3h1
RING CCCH (C3H) domains 1
chr3_+_152058937 1.586 NM_001080755
Zzz3
zinc finger, ZZ domain containing 3
chr14_-_26588341 1.571 NM_001101433
Zcchc24
zinc finger, CCHC domain containing 24
chr15_+_89330287 1.553 NM_021423
Shank3
SH3/ankyrin domain gene 3
chr9_-_65756482 1.546 NM_019797
Trip4
thyroid hormone receptor interactor 4
chr3_+_152059620 1.528 NM_198416
Zzz3
zinc finger, ZZ domain containing 3
chr13_+_24730516 1.502 NM_001080381
NM_029679
Fam65b

family with sequence similarity 65, member B

chr7_+_96552871 1.499 NM_008055
Fzd4
frizzled homolog 4 (Drosophila)
chr7_+_133415982 1.490 NM_145587
Sbk1
SH3-binding kinase 1
chr4_-_131628011 1.487 NM_183428
Epb4.1
erythrocyte protein band 4.1
chr9_-_104165221 1.474 NM_001163026
Dnajc13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr19_-_34953810 1.468 NM_001114339
Pank1
pantothenate kinase 1
chr11_-_78510874 1.465 NM_008702
Nlk
nemo like kinase
chr9_+_57787915 1.464 NM_011352
Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr18_+_51277551 1.458 NM_001081224
Prr16
proline rich 16
chr17_+_73267643 1.457 NM_029999
Lbh
limb-bud and heart
chr1_+_19198994 1.453 NM_009334
Tcfap2b
transcription factor AP-2 beta
chr5_-_73647856 1.427 NM_028194
Fryl
furry homolog-like (Drosophila)
chr10_+_120802099 1.408 NM_029364
Gns
glucosamine (N-acetyl)-6-sulfatase
chr19_-_34329804 1.408 NM_007392
Acta2
actin, alpha 2, smooth muscle, aorta
chr18_-_39078304 1.403 NM_010197
Fgf1
fibroblast growth factor 1
chr1_+_88199795 1.388 NM_145222
B3gnt7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr3_+_131748252 1.388 NM_020265
Dkk2
dickkopf homolog 2 (Xenopus laevis)
chr17_+_28938070 1.379 NM_001081315
Brpf3
bromodomain and PHD finger containing, 3
chr1_+_95700522 1.377 NM_025454
Ing5
inhibitor of growth family, member 5
chr2_+_25036276 1.373 NM_025980
Nrarp
Notch-regulated ankyrin repeat protein
chr10_-_78054639 1.368 NM_027875
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr2_+_119151519 1.367 NM_019454
Dll4
delta-like 4 (Drosophila)
chr18_+_84257471 1.354 NM_146090
Zadh2
zinc binding alcohol dehydrogenase, domain containing 2
chr16_-_35490849 1.349 NM_028295
Pdia5
protein disulfide isomerase associated 5
chr19_+_46673553 1.346 NM_001177812
NM_146099
D19Wsu162e

DNA segment, Chr 19, Wayne State University 162, expressed

chr7_+_127821093 1.345 NM_001164580
BC030336
cDNA sequence BC030336
chr16_-_44016471 1.326 NM_153528
Gramd1c
GRAM domain containing 1C
chr5_-_25004598 1.318 NM_001081383
Mll3
myeloid/lymphoid or mixed-lineage leukemia 3
chr2_+_18598644 1.310 NM_007552
Bmi1
Bmi1 polycomb ring finger oncogene
chr6_-_116143380 1.308 NM_177412
Tmcc1
transmembrane and coiled coil domains 1
chr5_+_73872293 1.304 NM_001190734
Dcun1d4
DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)
chr11_-_88579517 1.302 NM_054043
Msi2
Musashi homolog 2 (Drosophila)
chr1_-_160887568 1.300 NM_001085376
Pappa2
pappalysin 2
chr13_+_37980739 1.295 NM_001177869
Rreb1
ras responsive element binding protein 1
chr15_-_38008565 1.294 NM_001081359
NM_001112721
Ubr5

ubiquitin protein ligase E3 component n-recognin 5

chr8_-_125201971 1.290 NM_001109873
NM_177289
Cbfa2t3

core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)

chr2_-_39046224 1.285 NM_178778
Scai
suppressor of cancer cell invasion
chr5_+_75548309 1.272 NM_011058
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr19_+_3851772 1.264 NM_001025566
NM_013490
Chka

choline kinase alpha

chr11_-_74981653 1.260 NM_001098203
Hic1
hypermethylated in cancer 1
chr8_-_105308910 1.259 NM_009866
Cdh11
cadherin 11
chr1_+_61034757 1.258 NM_017480
Icos
inducible T-cell co-stimulator
chr4_+_97248556 1.250 NM_001122952
Nfia
D130039L10Rik
nuclear factor I/A
RIKEN cDNA D130039L10 gene
chr5_-_144493077 1.249 NM_029749
Usp42
ubiquitin specific peptidase 42
chr6_-_52154455 1.238 NM_010453
Hoxa5
homeobox A5
chr4_+_21774729 1.220 NM_025669
Sfrs18
serine/arginine-rich splicing factor 18
chr16_-_4523051 1.213 NM_175347
Srl
sarcalumenin
chr14_+_18493380 1.213 NM_001113417
Thrb
thyroid hormone receptor beta
chr11_+_79153388 1.212 NM_010897
Nf1
neurofibromatosis 1
chr4_+_125781197 1.194 NM_001145827
NM_028800
Stk40

serine/threonine kinase 40

chr1_-_138850206 1.193 NM_001159769
Nr5a2
nuclear receptor subfamily 5, group A, member 2
chr13_-_46823191 1.191 NM_175749
Nup153
nucleoporin 153
chr8_+_24085309 1.189 NM_001110783
Ank1
ankyrin 1, erythroid
chr15_-_57907967 1.181 NM_001042438
NM_009572
Zhx1

zinc fingers and homeoboxes 1

chr18_-_61336629 1.179 NM_178277
NM_134134
Hmgxb3

HMG box domain containing 3

chr13_+_112476313 1.162 NM_172593
Mier3
mesoderm induction early response 1, family member 3
chr11_-_20731016 1.161 NM_173752
1110067D22Rik
RIKEN cDNA 1110067D22 gene
chr2_+_32390780 1.161 NM_153560
Fam102a
family with sequence similarity 102, member A
chr4_-_148001104 1.150 NM_001003898
NM_001003899
NM_001008545
NM_001008546
NM_145556
Tardbp




TAR DNA binding protein




chr15_-_96886327 1.139 NM_027052
Slc38a4
solute carrier family 38, member 4
chr17_+_71533317 1.135 NM_022882
Lpin2
lipin 2
chr17_+_87153083 1.108 NM_010137
Epas1
endothelial PAS domain protein 1
chr10_-_70700764 1.108 NM_009360
Tfam
transcription factor A, mitochondrial
chr10_+_43198945 1.105 NM_199028
Bend3
BEN domain containing 3
chr9_-_119893775 1.105 NM_153287
Csrnp1
cysteine-serine-rich nuclear protein 1
chr10_+_96079634 1.097 NM_007569
Btg1
B-cell translocation gene 1, anti-proliferative
chr2_-_90910332 1.093 NM_026721
Slc39a13
solute carrier family 39 (metal ion transporter), member 13
chr16_+_52031661 1.091 NM_001033238
Cblb
Casitas B-lineage lymphoma b
chr12_+_71926429 1.080 NM_028127
Frmd6
FERM domain containing 6
chr1_-_69732373 1.072 NM_011770
Ikzf2
IKAROS family zinc finger 2
chr5_-_33196860 1.066 NM_194340
C330019G07Rik
RIKEN cDNA C330019G07 gene
chr11_+_45869473 1.064 NM_009616
Adam19
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr2_-_5635547 1.063 NM_177343
Camk1d
calcium/calmodulin-dependent protein kinase ID
chr14_-_35315715 1.058 NM_009758
Bmpr1a
bone morphogenetic protein receptor, type 1A
chr2_-_37502738 1.052 NM_009261
Strbp
spermatid perinuclear RNA binding protein
chr6_+_86354212 1.047 NM_001164078
NM_001164079
NM_011585
Tia1


cytotoxic granule-associated RNA binding protein 1


chr11_+_72861327 1.036 NM_025818
1200014J11Rik
RIKEN cDNA 1200014J11 gene
chr9_-_36954858 1.029 NM_148950
Pknox2
Pbx/knotted 1 homeobox 2
chr4_-_122638401 1.026 NM_029662
Mfsd2a
major facilitator superfamily domain containing 2A
chr18_+_32322742 1.014 NM_011946
Map3k2
mitogen-activated protein kinase kinase kinase 2
chr9_-_36954842 1.008 NM_001029838
Pknox2
Pbx/knotted 1 homeobox 2
chr11_-_103128675 1.006 NM_016896
Map3k14
mitogen-activated protein kinase kinase kinase 14
chr16_+_33185137 1.005 NM_176840
Osbpl11
oxysterol binding protein-like 11
chr18_+_24364442 1.003 NM_001160404
Galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr8_+_24168730 0.989 NM_031158
Ank1
ankyrin 1, erythroid
chr17_+_47767638 0.988 NM_198421
Usp49
ubiquitin specific peptidase 49
chr2_-_79969095 0.988 NM_016744
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr9_+_102620096 0.985 NM_019764
Amotl2
angiomotin-like 2
chr12_+_82960953 0.979 NM_018814
Pcnx
pecanex homolog (Drosophila)
chr9_-_106691395 0.973 NM_030730
Rad54l2
RAD54 like 2 (S. cerevisiae)
chr11_+_93747419 0.972 NM_134012
Mbtd1
mbt domain containing 1
chr19_+_53217238 0.969 NM_001164100
Add3
adducin 3 (gamma)
chr5_+_97426665 0.967 NM_080708
Bmp2k
BMP2 inducible kinase
chr1_-_107253245 0.957 NM_001160368
NM_178779
Rnf152

ring finger protein 152

chr9_+_13632152 0.947 NM_176836
Fam76b
family with sequence similarity 76, member B
chr5_-_110877489 0.939 NM_001142642
Fbrsl1
fibrosin-like 1
chr12_-_70825850 0.937 NM_145443
L2hgdh
L-2-hydroxyglutarate dehydrogenase
chr19_+_8831563 0.928 NM_016813
Nxf1
nuclear RNA export factor 1 homolog (S. cerevisiae)
chr6_+_14851348 0.925 NM_053242
Foxp2
forkhead box P2
chr7_+_119902897 0.922 NM_001166585
Tead1
TEA domain family member 1
chr13_-_64376186 0.918 NM_172587
Cdc14b
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr16_+_77013880 0.903 NM_013918
Usp25
ubiquitin specific peptidase 25
chr4_-_82151180 0.900 NM_001113209
NM_001113210
NM_008687
Nfib


nuclear factor I/B


chr7_-_77511607 0.899 NM_183261
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr2_-_120796395 0.898 NM_009461
Ubr1
ubiquitin protein ligase E3 component n-recognin 1
chr16_+_92058498 0.895 NM_080456
NM_017391
Mrps6
Slc5a3
mitochondrial ribosomal protein S6
solute carrier family 5 (inositol transporters), member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.48 6.99e-22 GO:0051252 regulation of RNA metabolic process
2.34 7.18e-22 GO:0031326 regulation of cellular biosynthetic process
2.33 8.92e-22 GO:0009889 regulation of biosynthetic process
2.12 9.66e-22 GO:0031323 regulation of cellular metabolic process
2.12 1.18e-21 GO:0080090 regulation of primary metabolic process
2.15 1.40e-21 GO:0060255 regulation of macromolecule metabolic process
2.41 1.47e-21 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.35 1.65e-21 GO:0010468 regulation of gene expression
2.48 3.28e-21 GO:0006355 regulation of transcription, DNA-dependent
2.30 9.75e-21 GO:0051171 regulation of nitrogen compound metabolic process
2.31 1.00e-20 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.35 1.73e-20 GO:0010556 regulation of macromolecule biosynthetic process
1.98 1.01e-19 GO:0019222 regulation of metabolic process
2.61 1.34e-17 GO:0006351 transcription, DNA-dependent
2.61 1.54e-17 GO:0032774 RNA biosynthetic process
3.29 4.78e-17 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.77 3.05e-15 GO:0044260 cellular macromolecule metabolic process
3.17 4.02e-15 GO:0031328 positive regulation of cellular biosynthetic process
3.47 4.26e-15 GO:0051254 positive regulation of RNA metabolic process
3.47 8.31e-15 GO:0045893 positive regulation of transcription, DNA-dependent
3.11 1.18e-14 GO:0009891 positive regulation of biosynthetic process
3.22 1.80e-14 GO:0010557 positive regulation of macromolecule biosynthetic process
3.19 3.12e-14 GO:0051173 positive regulation of nitrogen compound metabolic process
3.22 3.28e-14 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.72 3.32e-14 GO:0031325 positive regulation of cellular metabolic process
2.74 3.52e-14 GO:0010604 positive regulation of macromolecule metabolic process
3.29 3.76e-14 GO:0010628 positive regulation of gene expression
2.65 4.76e-14 GO:0009893 positive regulation of metabolic process
1.69 5.81e-14 GO:0043170 macromolecule metabolic process
2.11 2.30e-13 GO:0048522 positive regulation of cellular process
2.04 2.48e-13 GO:0048518 positive regulation of biological process
2.13 5.30e-13 GO:0034645 cellular macromolecule biosynthetic process
2.11 9.94e-13 GO:0009059 macromolecule biosynthetic process
3.71 1.07e-12 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.07 2.20e-11 GO:0016070 RNA metabolic process
1.85 3.70e-10 GO:0044249 cellular biosynthetic process
1.82 7.09e-10 GO:0009058 biosynthetic process
1.49 8.22e-10 GO:0044238 primary metabolic process
1.91 1.02e-09 GO:0090304 nucleic acid metabolic process
1.50 1.12e-09 GO:0044237 cellular metabolic process
1.91 4.85e-09 GO:0010467 gene expression
1.77 1.05e-08 GO:0032502 developmental process
1.80 2.43e-08 GO:0007275 multicellular organismal development
1.84 3.74e-08 GO:0048856 anatomical structure development
1.74 7.29e-08 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.88 1.05e-07 GO:0048731 system development
2.10 1.47e-07 GO:0006464 protein modification process
2.03 6.73e-07 GO:0043412 macromolecule modification
2.01 7.66e-07 GO:0048513 organ development
1.36 9.51e-07 GO:0050794 regulation of cellular process
1.38 1.23e-06 GO:0008152 metabolic process
1.87 2.36e-06 GO:0048523 negative regulation of cellular process
2.64 2.47e-06 GO:0031327 negative regulation of cellular biosynthetic process
2.82 2.65e-06 GO:0051253 negative regulation of RNA metabolic process
1.61 3.24e-06 GO:0006807 nitrogen compound metabolic process
1.62 3.92e-06 GO:0034641 cellular nitrogen compound metabolic process
2.58 5.28e-06 GO:0009890 negative regulation of biosynthetic process
2.98 6.11e-06 GO:0072358 cardiovascular system development
2.98 6.11e-06 GO:0072359 circulatory system development
3.20 7.54e-06 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.33 8.22e-06 GO:0050789 regulation of biological process
2.65 1.19e-05 GO:0010629 negative regulation of gene expression
2.63 1.42e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.73 1.69e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.31 1.75e-05 GO:0065007 biological regulation
2.60 2.04e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.59 2.22e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
2.55 2.27e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
2.25 2.86e-05 GO:0050793 regulation of developmental process
1.76 2.89e-05 GO:0048519 negative regulation of biological process
3.32 3.09e-05 GO:0007167 enzyme linked receptor protein signaling pathway
2.05 3.57e-05 GO:0009653 anatomical structure morphogenesis
2.55 5.18e-05 GO:0006468 protein phosphorylation
2.31 5.80e-05 GO:0042127 regulation of cell proliferation
2.23 8.96e-05 GO:0031324 negative regulation of cellular metabolic process
2.17 9.08e-05 GO:0009892 negative regulation of metabolic process
1.81 9.39e-05 GO:0030154 cell differentiation
2.22 1.03e-04 GO:0010605 negative regulation of macromolecule metabolic process
2.31 1.13e-04 GO:2000026 regulation of multicellular organismal development
3.25 1.49e-04 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
3.94 1.63e-04 GO:0071495 cellular response to endogenous stimulus
1.74 1.75e-04 GO:0044267 cellular protein metabolic process
4.08 1.86e-04 GO:0032870 cellular response to hormone stimulus
2.37 1.87e-04 GO:0045595 regulation of cell differentiation
2.18 1.89e-04 GO:0006796 phosphate metabolic process
2.18 2.02e-04 GO:0006793 phosphorus metabolic process
1.76 3.42e-04 GO:0048869 cellular developmental process
2.94 4.02e-04 GO:0032583 regulation of gene-specific transcription
2.75 4.46e-04 GO:0009967 positive regulation of signal transduction
2.02 5.41e-04 GO:0009966 regulation of signal transduction
1.91 5.64e-04 GO:0023051 regulation of signaling
2.26 7.27e-04 GO:0016310 phosphorylation
3.10 1.07e-03 GO:0035295 tube development
3.28 1.12e-03 GO:0018193 peptidyl-amino acid modification
2.04 1.93e-03 GO:0051246 regulation of protein metabolic process
1.18 2.64e-03 GO:0009987 cellular process
2.01 2.73e-03 GO:0010646 regulation of cell communication
3.01 2.94e-03 GO:0001944 vasculature development
2.51 3.22e-03 GO:0010647 positive regulation of cell communication
1.83 3.30e-03 GO:0051239 regulation of multicellular organismal process
2.23 3.44e-03 GO:0031399 regulation of protein modification process
4.08 3.45e-03 GO:0050678 regulation of epithelial cell proliferation
2.50 3.65e-03 GO:0023056 positive regulation of signaling
2.06 3.88e-03 GO:0032268 regulation of cellular protein metabolic process
10.71 4.38e-03 GO:0018210 peptidyl-threonine modification
3.09 5.15e-03 GO:0030334 regulation of cell migration
7.31 5.19e-03 GO:0043401 steroid hormone mediated signaling pathway
3.76 5.21e-03 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.77 5.69e-03 GO:0048583 regulation of response to stimulus
2.18 6.30e-03 GO:0048584 positive regulation of response to stimulus
1.56 6.43e-03 GO:0019538 protein metabolic process
3.05 6.47e-03 GO:2000145 regulation of cell motility
2.94 7.14e-03 GO:0051270 regulation of cellular component movement
3.36 7.35e-03 GO:0043193 positive regulation of gene-specific transcription
2.55 7.45e-03 GO:0071310 cellular response to organic substance
1.90 8.73e-03 GO:0007399 nervous system development
2.91 8.82e-03 GO:0040012 regulation of locomotion
2.43 8.91e-03 GO:0051094 positive regulation of developmental process
6.03 9.10e-03 GO:0032869 cellular response to insulin stimulus
2.68 9.45e-03 GO:0045597 positive regulation of cell differentiation
2.09 9.99e-03 GO:0048468 cell development
5.85 1.20e-02 GO:0071383 cellular response to steroid hormone stimulus
2.23 1.48e-02 GO:0019220 regulation of phosphate metabolic process
2.23 1.48e-02 GO:0051174 regulation of phosphorus metabolic process
2.25 1.66e-02 GO:0042325 regulation of phosphorylation
2.32 1.67e-02 GO:0001932 regulation of protein phosphorylation
2.87 1.71e-02 GO:0045596 negative regulation of cell differentiation
2.06 2.27e-02 GO:0009790 embryo development
39.77 2.63e-02 GO:0090245 axis elongation involved in somitogenesis
2.87 2.69e-02 GO:0001568 blood vessel development
2.71 2.77e-02 GO:0022603 regulation of anatomical structure morphogenesis
4.81 2.90e-02 GO:0032868 response to insulin stimulus
3.17 2.91e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.63 2.93e-02 GO:0007389 pattern specification process
1.93 3.16e-02 GO:0042981 regulation of apoptosis
2.56 3.17e-02 GO:0060284 regulation of cell development
2.93 3.25e-02 GO:0007507 heart development
2.61 3.35e-02 GO:0006325 chromatin organization
4.66 3.95e-02 GO:2000027 regulation of organ morphogenesis
1.91 4.22e-02 GO:0043067 regulation of programmed cell death
2.57 4.36e-02 GO:0051093 negative regulation of developmental process
1.48 4.48e-02 GO:0016043 cellular component organization
1.89 4.67e-02 GO:0032879 regulation of localization

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.35 1.82e-14 GO:0005622 intracellular
1.35 3.69e-14 GO:0044424 intracellular part
1.66 8.47e-13 GO:0005634 nucleus
1.40 1.01e-10 GO:0043231 intracellular membrane-bounded organelle
1.40 1.33e-10 GO:0043227 membrane-bounded organelle
1.35 9.22e-10 GO:0043229 intracellular organelle
1.34 1.37e-09 GO:0043226 organelle
1.17 1.37e-08 GO:0005623 cell
1.17 1.37e-08 GO:0044464 cell part
2.81 7.04e-08 GO:0044451 nucleoplasm part
1.31 4.26e-06 GO:0005737 cytoplasm
2.18 1.98e-05 GO:0005654 nucleoplasm
1.93 4.01e-05 GO:0031981 nuclear lumen
1.76 2.27e-04 GO:0044428 nuclear part
1.77 3.90e-04 GO:0070013 intracellular organelle lumen
1.77 4.17e-04 GO:0043233 organelle lumen
1.76 4.40e-04 GO:0031974 membrane-enclosed lumen
2.87 2.49e-03 GO:0005667 transcription factor complex
1.37 9.76e-03 GO:0044422 organelle part
1.36 1.42e-02 GO:0044446 intracellular organelle part
2.25 1.97e-02 GO:0045202 synapse
1.45 2.51e-02 GO:0043234 protein complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.36 2.65e-15 GO:0005488 binding
3.10 1.15e-11 GO:0001071 nucleic acid binding transcription factor activity
3.10 1.15e-11 GO:0003700 sequence-specific DNA binding transcription factor activity
2.44 2.91e-11 GO:0008270 zinc ion binding
1.75 1.31e-09 GO:0046872 metal ion binding
1.74 1.52e-09 GO:0043169 cation binding
1.73 2.00e-09 GO:0043167 ion binding
2.14 7.55e-09 GO:0046914 transition metal ion binding
2.07 1.42e-08 GO:0003677 DNA binding
2.58 1.89e-08 GO:0030528 transcription regulator activity
1.45 4.30e-07 GO:0005515 protein binding
2.77 4.34e-07 GO:0043565 sequence-specific DNA binding
2.83 2.18e-06 GO:0004672 protein kinase activity
2.60 4.04e-06 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.71 5.73e-06 GO:0003676 nucleic acid binding
3.26 3.04e-05 GO:0016563 transcription activator activity
2.31 6.16e-05 GO:0016301 kinase activity
3.09 4.06e-04 GO:0008134 transcription factor binding
2.77 4.92e-04 GO:0004674 protein serine/threonine kinase activity
3.37 8.49e-04 GO:0003712 transcription cofactor activity
3.36 9.06e-04 GO:0000989 transcription factor binding transcription factor activity
3.32 1.10e-03 GO:0000988 protein binding transcription factor activity
7.16 1.34e-03 GO:0003707 steroid hormone receptor activity
7.02 1.59e-03 GO:0004879 ligand-dependent nuclear receptor activity
2.03 1.70e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
2.08 1.83e-03 GO:0019899 enzyme binding
1.71 2.03e-03 GO:0016740 transferase activity
5.45 4.97e-03 GO:0019199 transmembrane receptor protein kinase activity
3.23 1.45e-02 GO:0010843 promoter binding
2.85 2.52e-02 GO:0019901 protein kinase binding
2.01 2.71e-02 GO:0046983 protein dimerization activity
2.65 2.81e-02 GO:0019900 kinase binding
3.03 3.11e-02 GO:0000975 regulatory region DNA binding
3.03 3.11e-02 GO:0001067 regulatory region nucleic acid binding
3.03 3.11e-02 GO:0044212 transcription regulatory region DNA binding
7.96 3.14e-02 GO:0035591 signaling adaptor activity
4.77 3.86e-02 GO:0060090 binding, bridging