Motif ID: UCACAUU

Z-value: 1.033


Mature miRNA associated with seed UCACAUU:

NamemiRBase Accession
mmu-miR-23a MIMAT0000532
mmu-miR-23b MIMAT0000125



Activity profile for motif UCACAUU.

activity profile for motif UCACAUU


Sorted Z-values histogram for motif UCACAUU

Sorted Z-values for motif UCACAUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCACAUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_51971946 26.935 NM_009122
Satb1
special AT-rich sequence binding protein 1
chr17_-_51951378 25.178 NM_001163630
Satb1
special AT-rich sequence binding protein 1
chr17_-_51972514 22.922 NM_001163632
Satb1
special AT-rich sequence binding protein 1
chr17_-_51965912 20.646 NM_001163631
Satb1
special AT-rich sequence binding protein 1
chr11_-_79894401 12.488 NM_018776
Crlf3
cytokine receptor-like factor 3
chr11_+_53583927 12.223 NM_001159396
Irf1
interferon regulatory factor 1
chr9_-_85220730 11.412 NM_001160378
NM_001160379
Fam46a

family with sequence similarity 46, member A

chr5_+_65194749 11.052 NM_008453
Klf3
Kruppel-like factor 3 (basic)
chr10_-_18731766 10.809 NM_001166402
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr8_+_59990639 10.536 NM_008252
Hmgb2
high mobility group box 2
chr8_-_125201971 10.528 NM_001109873
NM_177289
Cbfa2t3

core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)

chr13_-_112599181 10.271 NM_011945
Map3k1
mitogen-activated protein kinase kinase kinase 1
chr1_+_140860285 10.256 NM_001166501
Dennd1b
DENN/MADD domain containing 1B
chr15_+_80541675 10.130 NM_144812
Tnrc6b
trinucleotide repeat containing 6b
chr4_+_129497951 9.782 NM_001164745
Ptp4a2
5830469G19Rik
protein tyrosine phosphatase 4a2
RIKEN cDNA 5830469G19 gene
chr10_-_18735154 9.651 NM_009397
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr3_-_19211000 9.333 NM_001122759
Pde7a
phosphodiesterase 7A
chr8_-_125222837 9.202 NM_009824
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr11_-_100711785 9.087 NM_001113563
Stat5b
signal transducer and activator of transcription 5B
chr4_-_34830178 9.082 NM_013889
Zfp292
zinc finger protein 292
chr15_-_5193681 8.636 NM_001136079
NM_008965
Ptger4

prostaglandin E receptor 4 (subtype EP4)

chr3_-_83844042 8.513 NM_172681
D930015E06Rik
RIKEN cDNA D930015E06 gene
chr16_+_52031661 8.470 NM_001033238
Cblb
Casitas B-lineage lymphoma b
chr3_-_19164956 8.086 NM_008802
Pde7a
phosphodiesterase 7A
chr6_+_15670660 7.852 NM_175088
Mdfic
MyoD family inhibitor domain containing
chr4_+_102262447 7.765 NM_001177981
Pde4b
phosphodiesterase 4B, cAMP specific
chr2_-_104656852 7.751 NM_001123327
Qser1
glutamine and serine rich 1
chr11_+_6446883 7.713 NM_001190343
NM_146014
Ccm2

cerebral cavernous malformation 2 homolog (human)

chr2_-_6805937 7.647 NM_001110228
NM_001160293
NM_010160
Celf2


CUGBP, Elav-like family member 2


chr4_+_102260162 7.421 NM_001177982
Pde4b
phosphodiesterase 4B, cAMP specific
chr15_+_80629020 7.321 NM_177124
Tnrc6b
trinucleotide repeat containing 6b
chr1_+_140864297 7.113 NM_181347
Dennd1b
DENN/MADD domain containing 1B
chr16_+_24393435 7.070 NM_178665
Lpp
LIM domain containing preferred translocation partner in lipoma
chr9_-_116084395 7.066 NM_009371
NM_029575
Tgfbr2

transforming growth factor, beta receptor II

chr19_+_32832002 6.846 NM_008960
Pten
phosphatase and tensin homolog
chr4_+_102242664 6.763 NM_001177980
Pde4b
phosphodiesterase 4B, cAMP specific
chr4_+_129497720 6.707 NM_008974
Ptp4a2
protein tyrosine phosphatase 4a2
chr1_+_134212642 6.688 NM_001195025
NM_028778
Nuak2

NUAK family, SNF1-like kinase, 2

chr6_-_39156706 6.626 NM_001033430
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr10_+_79451332 6.618 NM_007725
Cnn2
calponin 2
chr19_+_37000568 6.577 NM_001080706
Btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, (Mot1 homolog, S. cerevisiae)
chr19_+_56471580 6.362 NM_007611
Casp7
caspase 7
chr11_+_53583515 6.283 NM_001159393
NM_008390
Irf1

interferon regulatory factor 1

chr9_+_30838224 6.271 NM_001115130
NM_172765
Zbtb44

zinc finger and BTB domain containing 44

chr17_+_31701700 6.179 NM_016670
Pknox1
Pbx/knotted 1 homeobox
chr2_-_144096253 6.139 NM_024225
Snx5
sorting nexin 5
chr14_+_99445595 6.126 NM_175265
6720463M24Rik
RIKEN cDNA 6720463M24 gene
chr1_+_39957733 6.013 NM_008696
Map4k4
mitogen-activated protein kinase kinase kinase kinase 4
chr13_-_99696254 5.855 NM_178716
Tnpo1
transportin 1
chr13_+_44826121 5.797 NM_021878
Jarid2
jumonji, AT rich interactive domain 2
chrX_+_82819294 5.715 NM_025729
Tab3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr7_+_87331726 5.683 NM_013659
Sema4b
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr6_+_17413930 5.413 NM_008591
Met
met proto-oncogene
chr16_-_32079317 5.362 NM_177326
Pak2
p21 protein (Cdc42/Rac)-activated kinase 2
chr2_+_160471623 5.330 NM_009408
Top1
topoisomerase (DNA) I
chr11_+_77499638 5.319 NM_001024205
Nufip2
nuclear fragile X mental retardation protein interacting protein 2
chr2_-_7317824 5.212 NM_001110231
Celf2
CUGBP, Elav-like family member 2
chr13_-_99660903 5.158 NM_001048267
Tnpo1
transportin 1
chr18_+_49992650 5.151 NM_001081371
Dmxl1
Dmx-like 1
chr5_+_145928011 5.132 NM_178576
Cpsf4
cleavage and polyadenylation specific factor 4
chr9_-_14556556 5.048 NM_010242
Fut4
fucosyltransferase 4
chr6_+_38383918 5.047 NM_177185
Ubn2
ubinuclein 2
chr16_+_24721940 5.046 NM_001145954
Lpp
LIM domain containing preferred translocation partner in lipoma
chrX_+_17739762 5.034 NM_009483
Kdm6a
4lysine (K)-specific demethylase 6A
chr4_+_15192892 5.011 NM_181401
Tmem64
transmembrane protein 64
chr3_-_51129908 5.006 NM_023502
Elf2
E74-like factor 2
chr12_-_113146259 4.972 NM_011625
Ppp1r13b
protein phosphatase 1, regulatory (inhibitor) subunit 13B
chr16_+_24448176 4.915 NM_001145952
Lpp
LIM domain containing preferred translocation partner in lipoma
chr14_+_15535538 4.865 NM_001033270
Slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr2_+_163899842 4.852 NM_021420
Stk4
serine/threonine kinase 4
chr10_-_36858671 4.796 NM_008538
Marcks
myristoylated alanine rich protein kinase C substrate
chr2_+_153567020 4.736 NM_007896
Mapre1
microtubule-associated protein, RP/EB family, member 1
chr18_+_78135191 4.626 NM_001195633
5430411K18Rik
RIKEN cDNA 5430411K18 gene
chr2_+_103264218 4.606 NM_010125
Elf5
E74-like factor 5
chr1_+_107886982 4.513 NM_001122675
NM_001122676
Zcchc2

zinc finger, CCHC domain containing 2

chr4_+_155186568 4.464 NM_207678
Ccnl2
cyclin L2
chr11_+_45869473 4.354 NM_009616
Adam19
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr2_-_7317513 4.348 NM_001110232
Celf2
CUGBP, Elav-like family member 2
chr15_-_96472600 4.288 NM_001166456
Slc38a1
solute carrier family 38, member 1
chr8_+_47825098 4.268 NM_008391
Irf2
interferon regulatory factor 2
chr15_-_93105514 4.235 NM_001033275
Gxylt1
glucoside xylosyltransferase 1
chr1_+_53353919 4.207 NM_145517
Ormdl1
ORM1-like 1 (S. cerevisiae)
chr1_-_183772442 4.181 NM_133815
Lbr
lamin B receptor
chr5_-_66489416 4.139 NM_139065
Rbm47
RNA binding motif protein 47
chr16_+_45224449 4.106 NM_001037719
NM_177584
Btla

B and T lymphocyte associated

chr5_-_66542161 3.992 NM_178446
Rbm47
RNA binding motif protein 47
chr15_-_96472392 3.919 NM_134086
Slc38a1
solute carrier family 38, member 1
chr10_+_53316720 3.909 NM_025541
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr16_-_64786146 3.899 NM_028059
Zfp654
zinc finger protein 654
chr18_+_36720238 3.877 NM_175375
Ankhd1
ankyrin repeat and KH domain containing 1
chr5_-_66543123 3.778 NM_001127382
Rbm47
RNA binding motif protein 47
chr2_-_33286793 3.774 NM_001085507
Zbtb34
zinc finger and BTB domain containing 34
chr7_+_130267398 3.769 NM_144925
Tnrc6a
trinucleotide repeat containing 6a
chr13_-_104710374 3.673 NM_001005868
NM_021563
Erbb2ip

Erbb2 interacting protein

chr19_-_41922577 3.606 NM_177603
Frat2
frequently rearranged in advanced T-cell lymphomas 2
chr2_-_84265422 3.562 NM_018782
Calcrl
calcitonin receptor-like
chr18_+_73732352 3.557 NM_001039214
Mex3c
mex3 homolog C (C. elegans)
chr1_-_140516239 3.518 NM_021605
Nek7
NIMA (never in mitosis gene a)-related expressed kinase 7
chr14_+_26513611 3.487 NM_134084
Ppif
peptidylprolyl isomerase F (cyclophilin F)
chr8_+_108160437 3.479 NM_181322
Ctcf
CCCTC-binding factor
chr12_+_84973146 3.399 NM_027349
AA645497
Rbm25
expressed sequence AA645497
RNA binding motif protein 25
chr2_-_7002344 3.394 NM_001110229
NM_001110230
NM_001160292
Celf2


CUGBP, Elav-like family member 2


chr15_-_96473193 3.389 NM_001166458
Slc38a1
solute carrier family 38, member 1
chr15_+_84753817 3.350 NM_016714
Nup50
nucleoporin 50
chrX_-_45816308 3.330 NM_019680
Elf4
E74-like factor 4 (ets domain transcription factor)
chr5_+_142877419 3.315 NM_199068
Foxk1
forkhead box K1
chr11_-_106781995 3.269 NM_025481
Smurf2
SMAD specific E3 ubiquitin protein ligase 2
chr18_-_89063572 3.207 NM_018821
Socs6
suppressor of cytokine signaling 6
chr14_+_57506630 3.204 NM_029498
Zmym2
zinc finger, MYM-type 2
chr7_-_123182257 3.170 NM_001025559
Sox6
SRY-box containing gene 6
chr13_-_8870975 3.153 NM_001039388
Wdr37
WD repeat domain 37
chr1_-_13364092 3.140 NM_001077695
NM_008678
Ncoa2

nuclear receptor coactivator 2

chr7_+_105851755 3.090 NM_028410
Prkrir
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr14_-_75347637 3.074 NM_001033439
Lrch1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr5_+_30890386 3.053 NM_010608
Kcnk3
potassium channel, subfamily K, member 3
chr2_+_103252254 3.030 NM_001145813
Elf5
E74-like factor 5
chr11_-_74983756 3.002 NM_010430
Hic1
hypermethylated in cancer 1
chr12_+_112088488 2.963 NM_028365
Zfp839
zinc finger protein 839
chr15_-_82742536 2.958 NM_001114140
NM_013836
Tcf20

transcription factor 20

chr15_-_58046428 2.919 NM_026346
Fbxo32
F-box protein 32
chr17_-_44873596 2.913 NM_001145920
Runx2
runt related transcription factor 2
chr14_+_31832323 2.913 NM_001081251
Pbrm1
polybromo 1
chr9_-_96918641 2.877 NM_145134
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr5_+_124889925 2.859 NM_030241
Setd8
SET domain containing (lysine methyltransferase) 8
chr10_-_90634236 2.848 NM_001080129
NM_001080130
NM_001080131
NM_001080132
NM_001080134
NM_011605
Tmpo





thymopoietin





chr3_-_115710131 2.830 NM_023214
Slc30a7
solute carrier family 30 (zinc transporter), member 7
chr8_+_36650839 2.738 NM_001081279
Mfhas1
malignant fibrous histiocytoma amplified sequence 1
chr15_+_59480204 2.725 NM_144549
Trib1
tribbles homolog 1 (Drosophila)
chr3_-_95622554 2.715 NM_001081293
Rprd2
regulation of nuclear pre-mRNA domain containing 2
chr4_+_48137778 2.586 NM_026343
Stx17
syntaxin 17
chr7_-_19895354 2.556 NM_008036
Fosb
FBJ osteosarcoma oncogene B
chr12_-_85749901 2.541 NM_001026214
NM_007647
Entpd5

ectonucleoside triphosphate diphosphohydrolase 5

chr2_-_33323966 2.512 NM_001025594
NM_027947
Zbtb43

zinc finger and BTB domain containing 43

chr5_+_104183148 2.508 NM_133919
Aff1
AF4/FMR2 family, member 1
chr11_+_66984528 2.505 NM_001039545
Myh2
myosin, heavy polypeptide 2, skeletal muscle, adult
chr17_-_44951745 2.427 NM_001146038
NM_009820
Runx2

runt related transcription factor 2

chrX_+_98449866 2.383 NM_018789
Foxo4
forkhead box O4
chr8_-_118230771 2.360 NM_001025577
Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr6_+_86354212 2.351 NM_001164078
NM_001164079
NM_011585
Tia1


cytotoxic granule-associated RNA binding protein 1


chr7_-_121261292 2.333 NM_025846
Rras2
related RAS viral (r-ras) oncogene homolog 2
chr11_-_100683830 2.332 NM_011489
Stat5b
signal transducer and activator of transcription 5B
chr4_-_6917628 2.296 NM_145711
Tox
thymocyte selection-associated high mobility group box
chr14_-_21000972 2.277 NM_021542
Kcnk5
potassium channel, subfamily K, member 5
chr11_+_117515548 2.266 NM_198022
Tnrc6c
trinucleotide repeat containing 6C
chr14_+_14845004 2.255 NM_139227
Atxn7
ataxin 7
chr5_+_97426665 2.237 NM_080708
Bmp2k
BMP2 inducible kinase
chr10_+_19654195 2.187 NM_008580
Map3k5
mitogen-activated protein kinase kinase kinase 5
chr5_+_104183591 2.144 NM_001080798
Aff1
AF4/FMR2 family, member 1
chr6_-_119988624 2.136 NM_001185020
NM_001185021
NM_198703
Wnk1


WNK lysine deficient protein kinase 1


chr2_+_164286416 2.122 NM_025575
Sys1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr19_-_4305954 2.121 NM_130863
Adrbk1
adrenergic receptor kinase, beta 1
chr6_+_83065466 2.119 NM_020619
Mogs
mannosyl-oligosaccharide glucosidase
chr1_-_63160764 2.115 NM_001081436
NM_001114609
Ino80d

INO80 complex subunit D

chr14_-_67627598 2.114 NM_009761
Bnip3l
BCL2/adenovirus E1B interacting protein 3-like
chr8_-_63433528 2.111 NM_173876
Clcn3
chloride channel 3
chr11_+_87476588 2.103 NM_172448
Rnf43
ring finger protein 43
chr11_-_84642465 2.088 NM_177564
Dhrs11
dehydrogenase/reductase (SDR family) member 11
chr6_-_83391623 2.062 NM_183138
Tet3
tet oncogene family member 3
chr17_-_31992708 2.050 NM_010831
Sik1
salt inducible kinase 1
chr2_+_119500777 1.992 NM_030112
Rtf1
Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr10_-_44178474 1.990 NM_007548
Prdm1
PR domain containing 1, with ZNF domain
chr3_-_89716963 1.951 NM_010559
Il6ra
interleukin 6 receptor, alpha
chr4_+_101927543 1.935 NM_019840
Pde4b
phosphodiesterase 4B, cAMP specific
chr12_-_76697166 1.875 NM_012024
Ppp2r5e
protein phosphatase 2, regulatory subunit B (B56), epsilon isoform
chr10_+_89207730 1.864 NM_029166
Uhrf1bp1l
UHRF1 (ICBP90) binding protein 1-like
chr5_-_107718503 1.860 NM_011578
Tgfbr3
transforming growth factor, beta receptor III
chr11_+_29072836 1.856 NM_134034
Smek2
SMEK homolog 2, suppressor of mek1 (Dictyostelium)
chr10_+_5958432 1.844 NM_001033466
Zbtb2
zinc finger and BTB domain containing 2
chr9_+_118387306 1.805 NM_001164789
NM_010136
Eomes

eomesodermin homolog (Xenopus laevis)

chr3_-_105604199 1.801 NM_145541
Rap1a
RAS-related protein-1a
chr11_-_40568710 1.792 NM_009831
Ccng1
cyclin G1
chr9_+_100978450 1.786 NM_001100451
Msl2
male-specific lethal 2 homolog (Drosophila)
chr18_-_57134974 1.756 NM_029909
C330018D20Rik
RIKEN cDNA C330018D20 gene
chr6_+_124254668 1.749 NM_001170395
NM_053094
Cd163

CD163 antigen

chr18_+_54021746 1.738 NM_152809
Csnk1g3
casein kinase 1, gamma 3
chr19_+_41904459 1.730 NM_008043
Frat1
frequently rearranged in advanced T-cell lymphomas
chr5_-_124875921 1.730 NM_001081203
Sbno1
sno, strawberry notch homolog 1 (Drosophila)
chr3_+_103718042 1.717 NM_172684
Rsbn1
rosbin, round spermatid basic protein 1
chr17_+_78599556 1.713 NM_015800
Crim1
cysteine rich transmembrane BMP regulator 1 (chordin like)
chr16_+_44139908 1.692 NM_028108
Naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr6_+_119429620 1.671 NM_133940
Fbxl14
F-box and leucine-rich repeat protein 14
chr2_-_28771940 1.667 NM_019446
NM_001164186
Barhl1

BarH-like 1 (Drosophila)

chr1_-_157820378 1.664 NM_001039184
Cep350
centrosomal protein 350
chr19_-_47538898 1.636 NM_001164717
NM_008018
Sh3pxd2a

SH3 and PX domains 2A

chr1_-_57028171 1.555 NM_139146
Satb2
special AT-rich sequence binding protein 2
chr14_-_70559239 1.555 NM_001004155
NM_001112735
9930012K11Rik

RIKEN cDNA 9930012K11 gene

chr2_-_70663453 1.543 NM_172664
Tlk1
tousled-like kinase 1
chr5_+_123526279 1.540 NM_001039723
Tmem120b
transmembrane protein 120B
chr11_+_93747419 1.537 NM_134012
Mbtd1
mbt domain containing 1
chr18_+_5591869 1.537 NM_011546
Zeb1
zinc finger E-box binding homeobox 1
chr4_-_115612507 1.530 NM_001025567
NM_130865
Dmbx1

diencephalon/mesencephalon homeobox 1

chr4_-_133523750 1.496 NM_016957
Hmgn2
high mobility group nucleosomal binding domain 2
chr10_-_62801726 1.496 NM_001159590
NM_019812
NM_001159589
Sirt1


sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)


chr4_+_105988790 1.462 NM_183225
Usp24
ubiquitin specific peptidase 24
chrX_+_21292025 1.460 NM_020049
Slc6a14
solute carrier family 6 (neurotransmitter transporter), member 14
chr11_-_50105794 1.453 NM_175334
Maml1
mastermind like 1 (Drosophila)
chr1_+_191552133 1.451 NM_008976
Ptpn14
protein tyrosine phosphatase, non-receptor type 14
chr8_-_108734817 1.412 NM_001007567
Slc7a6os
solute carrier family 7, member 6 opposite strand
chr13_-_46060325 1.403 NM_009124
Atxn1
ataxin 1
chr3_+_3508029 1.402 NM_013920
Hnf4g
hepatocyte nuclear factor 4, gamma

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.76 6.23e-23 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.71 1.51e-22 GO:0010556 regulation of macromolecule biosynthetic process
2.67 1.91e-22 GO:0010468 regulation of gene expression
2.37 3.40e-22 GO:0080090 regulation of primary metabolic process
2.40 4.08e-22 GO:0060255 regulation of macromolecule metabolic process
2.80 6.21e-22 GO:0051252 regulation of RNA metabolic process
2.10 9.84e-22 GO:0044260 cellular macromolecule metabolic process
2.60 1.46e-21 GO:0009889 regulation of biosynthetic process
2.61 1.67e-21 GO:0031326 regulation of cellular biosynthetic process
2.32 7.60e-21 GO:0031323 regulation of cellular metabolic process
2.58 1.16e-20 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.75 2.27e-20 GO:0006355 regulation of transcription, DNA-dependent
2.56 2.87e-20 GO:0051171 regulation of nitrogen compound metabolic process
2.18 5.95e-20 GO:0019222 regulation of metabolic process
1.95 6.19e-19 GO:0043170 macromolecule metabolic process
2.97 6.25e-18 GO:0006351 transcription, DNA-dependent
2.97 7.05e-18 GO:0032774 RNA biosynthetic process
2.57 9.25e-17 GO:0016070 RNA metabolic process
2.41 2.23e-15 GO:0010467 gene expression
2.36 2.87e-15 GO:0090304 nucleic acid metabolic process
1.70 9.08e-14 GO:0044237 cellular metabolic process
2.39 9.74e-14 GO:0009059 macromolecule biosynthetic process
1.68 1.52e-13 GO:0044238 primary metabolic process
2.38 1.68e-13 GO:0034645 cellular macromolecule biosynthetic process
2.13 2.26e-13 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.45 2.70e-13 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.57 6.63e-12 GO:0008152 metabolic process
1.97 4.99e-11 GO:0034641 cellular nitrogen compound metabolic process
1.95 5.37e-11 GO:0006807 nitrogen compound metabolic process
2.47 2.14e-09 GO:0006464 protein modification process
3.25 2.39e-09 GO:0010628 positive regulation of gene expression
2.42 2.50e-09 GO:0043412 macromolecule modification
1.98 3.28e-09 GO:0044249 cellular biosynthetic process
1.96 3.48e-09 GO:0009058 biosynthetic process
2.69 3.98e-09 GO:0010604 positive regulation of macromolecule metabolic process
2.22 4.36e-09 GO:0048523 negative regulation of cellular process
2.15 4.42e-09 GO:0048519 negative regulation of biological process
2.38 6.43e-09 GO:0048513 organ development
3.31 7.34e-09 GO:0045893 positive regulation of transcription, DNA-dependent
1.98 1.04e-08 GO:0007275 multicellular organismal development
3.26 1.20e-08 GO:0051254 positive regulation of RNA metabolic process
2.09 3.19e-08 GO:0048731 system development
3.24 8.15e-08 GO:0010558 negative regulation of macromolecule biosynthetic process
2.03 9.25e-08 GO:0048522 positive regulation of cellular process
3.29 9.31e-08 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.48 1.08e-07 GO:0009893 positive regulation of metabolic process
1.87 1.16e-07 GO:0032502 developmental process
3.14 1.23e-07 GO:0009890 negative regulation of biosynthetic process
1.45 1.25e-07 GO:0050794 regulation of cellular process
2.96 1.69e-07 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.27 2.07e-07 GO:0010629 negative regulation of gene expression
3.14 2.19e-07 GO:0031327 negative regulation of cellular biosynthetic process
1.42 2.26e-07 GO:0050789 regulation of biological process
2.91 2.67e-07 GO:0010557 positive regulation of macromolecule biosynthetic process
2.71 2.97e-07 GO:0009892 negative regulation of metabolic process
1.94 3.01e-07 GO:0048518 positive regulation of biological process
2.88 3.74e-07 GO:0051173 positive regulation of nitrogen compound metabolic process
1.94 6.41e-07 GO:0048856 anatomical structure development
2.75 6.68e-07 GO:0010605 negative regulation of macromolecule metabolic process
2.05 7.66e-07 GO:0044267 cellular protein metabolic process
9.77 8.54e-07 GO:0048704 embryonic skeletal system morphogenesis
3.14 1.12e-06 GO:0006468 protein phosphorylation
2.70 1.83e-06 GO:0031324 negative regulation of cellular metabolic process
3.36 1.83e-06 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.42 1.91e-06 GO:0031325 positive regulation of cellular metabolic process
3.80 2.30e-06 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
8.11 2.40e-06 GO:0048706 embryonic skeletal system development
2.71 2.53e-06 GO:0031328 positive regulation of cellular biosynthetic process
2.66 4.62e-06 GO:0009891 positive regulation of biosynthetic process
1.37 5.12e-06 GO:0065007 biological regulation
2.81 8.83e-06 GO:0009790 embryo development
3.15 8.91e-06 GO:0045892 negative regulation of transcription, DNA-dependent
2.99 1.13e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.10 1.29e-05 GO:0051253 negative regulation of RNA metabolic process
2.95 1.67e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
4.92 1.74e-05 GO:0071900 regulation of protein serine/threonine kinase activity
5.74 2.80e-05 GO:0048705 skeletal system morphogenesis
2.73 2.99e-05 GO:0016310 phosphorylation
3.46 5.97e-05 GO:0048598 embryonic morphogenesis
2.96 6.39e-05 GO:0042325 regulation of phosphorylation
1.81 7.37e-05 GO:0019538 protein metabolic process
2.46 9.37e-05 GO:0006796 phosphate metabolic process
2.46 9.93e-05 GO:0006793 phosphorus metabolic process
2.21 1.01e-04 GO:0009653 anatomical structure morphogenesis
3.84 1.12e-04 GO:0016568 chromatin modification
4.11 1.47e-04 GO:0001501 skeletal system development
1.23 1.49e-04 GO:0009987 cellular process
2.85 1.51e-04 GO:0019220 regulation of phosphate metabolic process
2.85 1.51e-04 GO:0051174 regulation of phosphorus metabolic process
2.28 1.95e-04 GO:0009966 regulation of signal transduction
3.65 2.63e-04 GO:0007243 intracellular protein kinase cascade
3.65 2.63e-04 GO:0023014 signal transduction via phosphorylation event
3.51 2.90e-04 GO:0045859 regulation of protein kinase activity
2.94 3.30e-04 GO:0001932 regulation of protein phosphorylation
3.46 3.69e-04 GO:0009968 negative regulation of signal transduction
3.58 3.76e-04 GO:0002520 immune system development
3.31 4.63e-04 GO:0051338 regulation of transferase activity
9.44 5.23e-04 GO:0018105 peptidyl-serine phosphorylation
2.39 6.10e-04 GO:0032268 regulation of cellular protein metabolic process
1.90 6.36e-04 GO:0030154 cell differentiation
3.31 8.10e-04 GO:0043549 regulation of kinase activity
3.03 8.12e-04 GO:0043009 chordate embryonic development
1.87 8.31e-04 GO:0048869 cellular developmental process
3.79 1.05e-03 GO:0048568 embryonic organ development
2.98 1.07e-03 GO:0009792 embryo development ending in birth or egg hatching
3.34 1.18e-03 GO:0006325 chromatin organization
12.56 1.39e-03 GO:0048701 embryonic cranial skeleton morphogenesis
2.93 1.51e-03 GO:0072358 cardiovascular system development
2.93 1.51e-03 GO:0072359 circulatory system development
3.17 1.70e-03 GO:0023057 negative regulation of signaling
3.16 1.77e-03 GO:0010648 negative regulation of cell communication
2.49 2.08e-03 GO:0045595 regulation of cell differentiation
2.24 2.33e-03 GO:0051246 regulation of protein metabolic process
4.41 2.36e-03 GO:0048562 embryonic organ morphogenesis
3.42 2.61e-03 GO:0048534 hemopoietic or lymphoid organ development
3.17 2.85e-03 GO:0045597 positive regulation of cell differentiation
7.58 3.56e-03 GO:0018209 peptidyl-serine modification
2.33 4.25e-03 GO:0009888 tissue development
1.98 6.36e-03 GO:0023051 regulation of signaling
2.42 7.93e-03 GO:0031399 regulation of protein modification process
4.55 8.35e-03 GO:0043405 regulation of MAP kinase activity
2.79 8.74e-03 GO:0048585 negative regulation of response to stimulus
2.78 9.38e-03 GO:0051276 chromosome organization
4.87 9.38e-03 GO:0071902 positive regulation of protein serine/threonine kinase activity
1.88 1.19e-02 GO:0048583 regulation of response to stimulus
3.19 1.28e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
2.33 1.57e-02 GO:0044093 positive regulation of molecular function
3.53 1.89e-02 GO:0061061 muscle structure development
7.18 1.96e-02 GO:0016458 gene silencing
2.11 2.02e-02 GO:0050793 regulation of developmental process
3.28 2.64e-02 GO:0030097 hemopoiesis
4.06 2.82e-02 GO:0000165 MAPKKK cascade
3.25 3.01e-02 GO:0001568 blood vessel development
41.70 3.06e-02 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway
3.95 3.78e-02 GO:0043010 camera-type eye development
2.44 3.87e-02 GO:0006915 apoptosis
5.06 3.96e-02 GO:0043406 positive regulation of MAP kinase activity
3.49 4.01e-02 GO:0048514 blood vessel morphogenesis
7.63 4.50e-02 GO:0001649 osteoblast differentiation
2.91 4.61e-02 GO:0007389 pattern specification process
3.27 4.82e-02 GO:0051347 positive regulation of transferase activity

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.14 1.23e-26 GO:0005634 nucleus
1.66 7.32e-21 GO:0043231 intracellular membrane-bounded organelle
1.65 1.00e-20 GO:0043227 membrane-bounded organelle
1.57 1.01e-19 GO:0043229 intracellular organelle
1.57 1.61e-19 GO:0043226 organelle
1.47 7.08e-19 GO:0044424 intracellular part
1.45 3.44e-18 GO:0005622 intracellular
2.47 2.95e-11 GO:0044428 nuclear part
3.00 2.37e-10 GO:0005654 nucleoplasm
2.58 3.86e-10 GO:0031981 nuclear lumen
3.42 2.25e-09 GO:0044451 nucleoplasm part
2.34 8.08e-09 GO:0070013 intracellular organelle lumen
2.33 8.76e-09 GO:0043233 organelle lumen
2.29 2.12e-08 GO:0031974 membrane-enclosed lumen
1.17 1.68e-06 GO:0005623 cell
1.17 1.68e-06 GO:0044464 cell part
1.52 4.34e-04 GO:0044446 intracellular organelle part
3.47 5.36e-04 GO:0005667 transcription factor complex
1.51 6.10e-04 GO:0044422 organelle part
1.31 6.41e-04 GO:0005737 cytoplasm
13.08 3.71e-02 GO:0005637 nuclear inner membrane
4.00 3.86e-02 GO:0016604 nuclear body

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.28 1.34e-13 GO:0003676 nucleic acid binding
1.39 1.64e-12 GO:0005488 binding
3.65 2.05e-12 GO:0001071 nucleic acid binding transcription factor activity
3.65 2.05e-12 GO:0003700 sequence-specific DNA binding transcription factor activity
3.30 8.40e-12 GO:0030528 transcription regulator activity
2.46 4.58e-11 GO:0003677 DNA binding
5.15 1.42e-10 GO:0016564 transcription repressor activity
3.52 1.38e-09 GO:0043565 sequence-specific DNA binding
3.73 1.36e-06 GO:0004674 protein serine/threonine kinase activity
4.26 1.56e-06 GO:0019900 kinase binding
4.65 1.56e-06 GO:0019901 protein kinase binding
3.14 5.49e-06 GO:0004672 protein kinase activity
2.64 9.55e-06 GO:0019899 enzyme binding
2.22 1.36e-05 GO:0008270 zinc ion binding
1.67 2.88e-05 GO:0046872 metal ion binding
1.65 5.05e-05 GO:0043169 cation binding
1.64 6.02e-05 GO:0043167 ion binding
2.71 9.48e-05 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.51 1.56e-04 GO:0016301 kinase activity
1.42 3.52e-04 GO:0005515 protein binding
3.37 6.54e-04 GO:0016563 transcription activator activity
1.89 7.77e-04 GO:0016740 transferase activity
4.11 1.13e-03 GO:0003682 chromatin binding
1.89 1.45e-03 GO:0046914 transition metal ion binding
2.22 1.90e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
8.28 5.16e-03 GO:0004702 receptor signaling protein serine/threonine kinase activity
13.90 6.05e-03 GO:0004709 MAP kinase kinase kinase activity
5.16 1.68e-02 GO:0016566 specific transcriptional repressor activity
5.85 1.74e-02 GO:0005057 receptor signaling protein activity
3.44 3.08e-02 GO:0000975 regulatory region DNA binding
3.44 3.08e-02 GO:0001067 regulatory region nucleic acid binding
3.44 3.08e-02 GO:0044212 transcription regulatory region DNA binding