Motif ID: UGUGCUU

Z-value: 2.907


Mature miRNA associated with seed UGUGCUU:

NamemiRBase Accession
mmu-miR-218 MIMAT0000663



Activity profile for motif UGUGCUU.

activity profile for motif UGUGCUU


Sorted Z-values histogram for motif UGUGCUU

Sorted Z-values for motif UGUGCUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UGUGCUU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_8913619 81.232 NM_010316
 Gng3
guanine nucleotide binding protein (G protein), gamma 3
chr6_+_114232618 76.637 NM_178703
 Slc6a1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr2_-_52532100 68.260 NM_001037099
 Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr2_-_52414072 67.797 NM_146123
 Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr3_+_95985065 60.757 NM_022030
 Sv2a
synaptic vesicle glycoprotein 2 a
chr1_-_25886551 59.332 NM_175642
 Bai3
brain-specific angiogenesis inhibitor 3
chr2_-_32702729 59.000 NM_009295
NM_001113569
 Stxbp1

syntaxin binding protein 1

chr3_-_117063793 58.432 NM_177664
 D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr7_+_64845887 55.740 NM_001038701
 Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr8_+_98226914 53.043 NM_001195006
NM_145602
 Ndrg4

N-myc downstream regulated gene 4

chr2_+_102498839 52.433 NM_001077514
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr11_+_42233258 50.961 NM_008070
 Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr5_+_27375738 49.475 NM_207282
 Dpp6
dipeptidylpeptidase 6
chr6_+_21166108 48.656 NM_019697
 Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr5_-_21850490 48.231 NM_011261
 Reln
reelin
chrX_+_140127827 48.081 NM_001195046
NM_001195047
 Pak3

p21 protein (Cdc42/Rac)-activated kinase 3

chr10_+_4424140 47.240 NM_001161822
NM_019958
 Rgs17

regulator of G-protein signaling 17

chr2_-_127347102 47.009 NM_019789
 Kcnip3
Kv channel interacting protein 3, calsenilin
chr15_+_30102306 46.132 NM_008729
 Ctnnd2
catenin (cadherin associated protein), delta 2
chr5_+_19413335 45.652 NM_001170745
NM_015823
 Magi2

membrane associated guanylate kinase, WW and PDZ domain containing 2


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 66 entries
Enrichment   P-value GO Accession GO Term
27.89 6.52e-03 GO:0048172 regulation of short-term neuronal synaptic plasticity
9.99 2.44e-04 GO:0007269 neurotransmitter secretion
9.76 3.13e-02 GO:0050805 negative regulation of synaptic transmission
8.14 2.34e-02 GO:0048489 synaptic vesicle transport
6.98 4.64e-05 GO:0006836 neurotransmitter transport
6.46 1.10e-02 GO:0007156 homophilic cell adhesion
6.42 3.73e-03 GO:0001505 regulation of neurotransmitter levels
5.82 4.06e-04 GO:0003001 generation of a signal involved in cell-cell signaling
5.82 4.06e-04 GO:0023061 signal release
5.79 1.54e-04 GO:0006887 exocytosis
4.58 1.02e-04 GO:0050804 regulation of synaptic transmission
4.54 8.43e-07 GO:0007268 synaptic transmission
4.51 2.20e-06 GO:0048812 neuron projection morphogenesis
4.50 2.62e-05 GO:0007409 axonogenesis
4.48 6.29e-05 GO:0051969 regulation of transmission of nerve impulse
4.21 3.49e-03 GO:0016311 dephosphorylation
4.12 2.35e-04 GO:0031644 regulation of neurological system process
4.10 1.22e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
4.05 9.69e-07 GO:0019226 transmission of nerve impulse
4.05 9.69e-07 GO:0035637 multicellular organismal signaling

Gene overrepresentation in compartment category:

Showing 1 to 20 of 43 entries
Enrichment   P-value GO Accession GO Term
17.75 1.10e-02 GO:0030673 axolemma
14.17 1.68e-06 GO:0044304 main axon
10.98 1.94e-05 GO:0042734 presynaptic membrane
10.10 4.87e-03 GO:0030672 synaptic vesicle membrane
9.39 3.49e-02 GO:0032589 neuron projection membrane
8.49 8.18e-04 GO:0043195 terminal button
6.66 4.77e-08 GO:0033267 axon part
6.10 5.96e-07 GO:0019717 synaptosome
6.02 3.79e-03 GO:0043197 dendritic spine
5.86 4.73e-03 GO:0044309 neuron spine
5.63 4.06e-12 GO:0030424 axon
5.43 1.11e-14 GO:0044456 synapse part
5.23 1.18e-02 GO:0044306 neuron projection terminus
5.01 4.16e-02 GO:0043679 axon terminus
4.71 4.21e-16 GO:0045202 synapse
4.70 1.17e-02 GO:0034703 cation channel complex
4.55 2.51e-04 GO:0045211 postsynaptic membrane
4.44 4.24e-02 GO:0008021 synaptic vesicle
4.28 2.43e-07 GO:0030425 dendrite
4.05 1.48e-13 GO:0043005 neuron projection

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
Enrichment   P-value GO Accession GO Term
16.27 2.18e-02 GO:0005248 voltage-gated sodium channel activity
10.10 6.53e-03 GO:0005272 sodium channel activity
4.10 2.35e-02 GO:0022843 voltage-gated cation channel activity
3.69 9.07e-05 GO:0022836 gated channel activity
3.53 2.59e-02 GO:0005244 voltage-gated ion channel activity
3.53 2.59e-02 GO:0022832 voltage-gated channel activity
3.50 1.32e-03 GO:0005261 cation channel activity
3.21 1.67e-04 GO:0005216 ion channel activity
3.17 1.23e-04 GO:0015267 channel activity
3.16 1.29e-04 GO:0022803 passive transmembrane transporter activity
3.14 2.47e-04 GO:0022838 substrate-specific channel activity
2.56 2.54e-02 GO:0060589 nucleoside-triphosphatase regulator activity
2.51 4.77e-02 GO:0030695 GTPase regulator activity
2.34 4.48e-02 GO:0008324 cation transmembrane transporter activity
2.18 2.27e-02 GO:0015075 ion transmembrane transporter activity
2.03 4.90e-02 GO:0022891 substrate-specific transmembrane transporter activity
1.44 2.69e-05 GO:0005515 protein binding
1.23 2.38e-04 GO:0005488 binding