Motif ID: XBP1.p3

Z-value: 3.573


Transcription factors associated with XBP1.p3:

Gene SymbolEntrez IDGene Name
Xbp1 22433 X-box binding protein 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Xbp1chr11_+_54209200.611.2e-19Click!


Activity profile for motif XBP1.p3.

activity profile for motif XBP1.p3


Sorted Z-values histogram for motif XBP1.p3

Sorted Z-values for motif XBP1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of XBP1.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_122970332 123.980 NM_027135
Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr7_-_52347489 96.985 NM_026555
Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr18_-_52689185 94.344 Lox
lysyl oxidase
chr3_-_27609279 84.821 NM_173182
Fndc3b
fibronectin type III domain containing 3B
chr7_+_123647881 65.040 NM_001130479
NM_016773
Nucb2

nucleobindin 2

chr10_+_90545834 62.540 Ikbip
IKBKB interacting protein
chr6_+_4455686 61.498 NM_007743
Col1a2
collagen, type I, alpha 2
chr4_-_11313886 60.625 NM_194055
Esrp1
epithelial splicing regulatory protein 1
chr7_-_52347012 58.529 Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr15_+_31154137 57.432 NM_146057
Dap
death-associated protein
chr18_-_52689279 56.836 NM_010728
Lox
lysyl oxidase
chr18_-_52689504 54.397 Lox
lysyl oxidase
chr2_-_143836838 54.137 NM_024281
NM_133626
Rrbp1

ribosome binding protein 1

chr10_+_90545782 53.500 NM_026166
NM_027078
Ikbip

IKBKB interacting protein

chr13_-_38619746 53.482 Txndc5
thioredoxin domain containing 5
chr13_-_38620109 53.147 Txndc5
thioredoxin domain containing 5
chr15_+_79346819 53.075 NM_134090
Kdelr3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr10_-_83996516 52.640 Ckap4
cytoskeleton-associated protein 4
chr13_-_38620304 52.194 Txndc5
thioredoxin domain containing 5
chr13_-_38620307 47.776 NM_145367
Txndc5
thioredoxin domain containing 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 53 entries
Enrichment   P-value GO Accession GO Term
55.00 6.63e-03 GO:0006042 glucosamine biosynthetic process
47.14 2.64e-07 GO:0006047 UDP-N-acetylglucosamine metabolic process
41.25 2.62e-02 GO:0071569 protein ufmylation
22.00 2.30e-02 GO:0048200 Golgi transport vesicle coating
22.00 2.30e-02 GO:0048205 COPI coating of Golgi vesicle
20.00 3.56e-02 GO:0048194 Golgi vesicle budding
19.41 4.01e-04 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
19.41 4.01e-04 GO:0009225 nucleotide-sugar metabolic process
18.33 5.54e-03 GO:0070972 protein localization in endoplasmic reticulum
17.37 8.52e-04 GO:0006041 glucosamine metabolic process
17.37 8.52e-04 GO:0006044 N-acetylglucosamine metabolic process
16.18 1.11e-02 GO:0006901 vesicle coating
13.75 2.65e-02 GO:0006900 membrane budding
12.69 6.49e-03 GO:0030433 ER-associated protein catabolic process
12.22 8.22e-03 GO:0006040 amino sugar metabolic process
11.38 1.28e-02 GO:0006488 dolichol-linked oligosaccharide biosynthetic process
10.76 1.32e-04 GO:0006487 protein N-linked glycosylation
9.17 4.71e-02 GO:0009312 oligosaccharide biosynthetic process
8.98 2.87e-03 GO:0009311 oligosaccharide metabolic process
8.92 1.72e-09 GO:0048193 Golgi vesicle transport

Gene overrepresentation in compartment category:

Showing 1 to 20 of 39 entries
Enrichment   P-value GO Accession GO Term
33.00 1.23e-02 GO:0005797 Golgi medial cisterna
27.50 2.43e-02 GO:0005786 signal recognition particle, endoplasmic reticulum targeting
27.50 2.43e-02 GO:0048500 signal recognition particle
22.92 2.92e-04 GO:0030663 COPI coated vesicle membrane
20.00 6.80e-03 GO:0030126 COPI vesicle coat
18.33 1.06e-03 GO:0030137 COPI-coated vesicle
11.38 2.44e-03 GO:0030120 vesicle coat
10.58 1.97e-02 GO:0030660 Golgi-associated vesicle membrane
8.75 2.81e-03 GO:0005788 endoplasmic reticulum lumen
8.75 2.81e-03 GO:0005798 Golgi-associated vesicle
7.10 3.35e-03 GO:0030117 membrane coat
7.10 3.35e-03 GO:0048475 coated membrane
6.31 1.23e-07 GO:0000139 Golgi membrane
6.29 8.24e-03 GO:0030662 coated vesicle membrane
5.14 7.82e-10 GO:0044431 Golgi apparatus part
4.38 1.57e-27 GO:0005783 endoplasmic reticulum
4.18 1.84e-06 GO:0044432 endoplasmic reticulum part
3.86 3.05e-02 GO:0030659 cytoplasmic vesicle membrane
3.82 1.69e-02 GO:0012506 vesicle membrane
3.74 4.02e-02 GO:0044433 cytoplasmic vesicle part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
4.96 3.97e-03 GO:0016853 isomerase activity
1.23 8.08e-04 GO:0005488 binding